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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs411326
log Bayes Factor = 37.4161
Chromosome 6   position 32,211,317  (GRCh37) Explore rs411326 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.004 0.996
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.959 0.041 0.000
L40.5 Arthropathic psoriasis
0.956 0.044 0.000
L40 Psoriasis
0.943 0.057 0.000
L40.9 Psoriasis, unspecified
0.942 0.058 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.938 0.062 0.000
D86.9 Sarcoidosis, unspecified
0.000 0.091 0.909
K51.9 Ulcerative colitis, unspecified
0.000 0.093 0.907
D86 Sarcoidosis
0.000 0.096 0.904
D50 Iron deficiency anaemia
0.000 0.101 0.899
D50-D53 Nutritional anaemias
0.000 0.107 0.893
D80-D89 Certain disorders involving the immune mechanism
0.000 0.113 0.887
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.115 0.885
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.116 0.884
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.124 0.876
D50.8 Other iron deficiency anaemias
0.000 0.125 0.875
C82.0 Small cleaved cell, follicular
0.872 0.128 0.000
E50-E64 Other nutritional deficiencies
0.000 0.129 0.871
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.145 0.855
E06 Thyroiditis
0.000 0.149 0.851
C82.1 Mixed small cleaved and large cell, follicular
0.848 0.152 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.159 0.841
E27 Other disorders of adrenal gland
0.000 0.163 0.837
E55 Vitamin D deficiency
0.000 0.163 0.837
D50.9 Iron deficiency anaemia, unspecified
0.000 0.165 0.835
E20-E35 Disorders of other endocrine glands
0.000 0.169 0.831
E07 Other disorders of thyroid
0.000 0.174 0.826
E55.9 Vitamin D deficiency, unspecified
0.000 0.187 0.813
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.813 0.187 0.000
D86.0 Sarcoidosis of lung
0.000 0.191 0.809
E53 Deficiency of other B group vitamins
0.000 0.202 0.798
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.206 0.794
D86.1 Sarcoidosis of lymph nodes
0.000 0.210 0.790
D68 Other coagulation defects
0.000 0.213 0.787
K51 Ulcerative colitis
0.000 0.231 0.769
C82.3 Follicular lymphoma grade IIIa
0.767 0.233 0.000
C82.2 Large cell, follicular
0.766 0.234 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.258 0.742
E53.8 Deficiency of other specified B group vitamins
0.000 0.260 0.740
D52 Folate deficiency anaemia
0.000 0.262 0.738
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E06.3 Autoimmune thyroiditis
0.000 0.284 0.716
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.288 0.712
K51.5 Mucosal proctocolitis
0.000 0.290 0.710
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.292 0.708
E07.8 Other specified disorders of thyroid
0.000 0.292 0.707
D68.5 Primary Thrombophilia
0.000 0.293 0.707
L40.4 Guttate psoriasis
0.707 0.293 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.296 0.704
D69 Purpura and other haemorrhagic conditions
0.000 0.303 0.697
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.315 0.685
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.000 0.323 0.677
L40.2 Acrodermatitis continua
0.676 0.324 0.000
C82.6 Cutaneous follicle centre lymphoma
0.672 0.328 0.000
C82.5 Diffuse follicle centre lymphoma
0.672 0.328 0.000
C82.4 Follicular lymphoma grade IIIb
0.672 0.328 0.000
E06.9 Thyroiditis, unspecified
0.000 0.332 0.668
D53 Other nutritional anaemias
0.000 0.340 0.660
D86.8 Sarcoidosis of other and combined sites
0.000 0.341 0.659
D66 Hereditary factor VIII deficiency
0.000 0.342 0.658
D51 Vitamin B12 deficiency anaemia
0.000 0.356 0.644
D50.1 Sideropenic dysphagia
0.000 0.356 0.644
E58 Dietary calcium deficiency
0.000 0.359 0.641
L40.1 Generalised pustular psoriasis
0.640 0.360 0.000
D82 Immunodeficiency associated with other major defects
0.000 0.364 0.636
D81 Combined immunodeficiencies
0.000 0.364 0.636
K51.8 Other ulcerative colitis
0.000 0.365 0.635
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.370 0.630
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.371 0.629
K90 Intestinal malabsorption
0.000 0.371 0.629
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.372 0.628
D68.0 Von Willebrand's disease
0.000 0.372 0.628
E51 Thiamine deficiency
0.000 0.373 0.627
D52.9 Folate deficiency anaemia, unspecified
0.000 0.373 0.627
D68.8 Other specified coagulation defects
0.000 0.375 0.625
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.375 0.624
E63 Other nutritional deficiencies
0.000 0.375 0.624
E56 Other vitamin deficiencies
0.000 0.375 0.624
E50 Vitamin A deficiency
0.000 0.375 0.624
E60 Dietary zinc deficiency
0.000 0.375 0.624
E59 Dietary selenium deficiency
0.000 0.375 0.624
E54 Ascorbic acid deficiency
0.000 0.375 0.624
E52 Niacin deficiency [pellagra]
0.000 0.375 0.624
L40.3 Pustulosis palmaris et plantaris
0.618 0.382 0.000
E61 Deficiency of other nutrient elements
0.000 0.383 0.617
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.386 0.614
D67 Hereditary factor IX deficiency
0.000 0.387 0.613
E06.4 Drug-induced thyroiditis
0.000 0.390 0.610
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.390 0.610
E06.1 Subacute thyroiditis
0.000 0.390 0.610
E06.0 Acute thyroiditis
0.000 0.390 0.610
E27.2 Addisonian crisis
0.000 0.390 0.610
E03.8 Other specified hypothyroidism
0.000 0.390 0.610
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.392 0.608
E06.5 Other chronic thyroiditis
0.000 0.399 0.601
E27.5 Adrenomedullary hyperfunction
0.000 0.400 0.600
E27.0 Other adrenocortical overactivity
0.000 0.400 0.600
E55.0 Rickets, active
0.000 0.400 0.600
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.404 0.596
E32 Diseases of thymus
0.000 0.404 0.596
E31 Polyglandular dysfunction
0.000 0.404 0.596
E30 Disorders of puberty, not elsewhere classified
0.000 0.404 0.596
E53.9 Vitamin B deficiency, unspecified
0.000 0.405 0.595
E05.8 Other thyrotoxicosis
0.000 0.406 0.594
E07.1 Dyshormogenetic goitre
0.000 0.408 0.592
E07.0 Hypersecretion of calcitonin
0.000 0.408 0.592
L40.8 Other psoriasis
0.589 0.410 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.417 0.583
E20 Hypoparathyroidism
0.000 0.418 0.582
D68.2 Hereditary deficiency of other clotting factors
0.000 0.418 0.582
D83 Common variable immunodeficiency
0.000 0.418 0.582
D68.1 Hereditary factor XI deficiency
0.000 0.418 0.582
E07.9 Disorder of thyroid, unspecified
0.000 0.419 0.581
E25 Adrenogenital disorders
0.000 0.425 0.575
E53.1 Pyridoxine deficiency
0.000 0.428 0.572
E53.0 Riboflavin deficiency
0.000 0.428 0.572
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.431 0.569
E29 Testicular dysfunction
0.000 0.434 0.566
D68.4 Acquired coagulation factor deficiency
0.000 0.436 0.564
D69.5 Secondary thrombocytopenia
0.000 0.437 0.563
D69.4 Other primary thrombocytopenia
0.000 0.446 0.554
L40-L45 Papulosquamous disorders
0.552 0.448 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.448 0.552
E10-E14 Diabetes mellitus
0.000 0.449 0.551
E16 Other disorders of pancreatic internal secretion
0.000 0.458 0.542
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.461 0.539
D52.8 Other folate deficiency anaemias
0.000 0.471 0.529
D52.1 Drug-induced folate deficiency anaemia
0.000 0.471 0.529
D52.0 Dietary folate deficiency anaemia
0.000 0.471 0.529
E10 Insulin-dependent diabetes mellitus
0.000 0.476 0.524
E34 Other endocrine disorders
0.000 0.479 0.521
D86.3 Sarcoidosis of skin
0.000 0.479 0.520
D69.0 Allergic purpura
0.000 0.482 0.518
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E61.2 Magnesium deficiency
0.000 0.490 0.510
D55-D59 Haemolytic anaemias
0.000 0.494 0.506
D84 Other immunodeficiencies
0.000 0.496 0.504
E28 Ovarian dysfunction
0.000 0.496 0.504
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.498 0.502
E10.9 Without complications
0.000 0.500 0.500
D69.8 Other specified haemorrhagic conditions
0.000 0.500 0.499
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.502 0.498
D69.9 Haemorrhagic condition, unspecified
0.000 0.503 0.497
D53.9 Nutritional anaemia, unspecified
0.000 0.506 0.494
E15 Nondiabetic hypoglycaemic coma
0.000 0.509 0.491
D69.2 Other nonthrombocytopenic purpura
0.000 0.514 0.486
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.514 0.486
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.517 0.483
E40-E46 Malnutrition
0.000 0.518 0.482
D68.6 Other Thrombophilia
0.000 0.523 0.477
D53.8 Other specified nutritional anaemias
0.000 0.526 0.473
D53.2 Scorbutic anaemia
0.000 0.526 0.473
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.526 0.473
D53.0 Protein deficiency anaemia
0.000 0.526 0.473
E27.9 Disorder of adrenal gland, unspecified
0.000 0.532 0.468
L43 Lichen planus
0.463 0.537 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.538 0.462
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.538 0.462
D51.2 Transcobalamin II deficiency
0.000 0.538 0.462
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.538 0.462
D81.9 Combined immunodeficiency, unspecified
0.000 0.544 0.456
D81.8 Other combined immunodeficiencies
0.000 0.544 0.456
D81.7 Major histocompatibility complex class II deficiency
0.000 0.544 0.456
D81.6 Major histocompatibility complex class I deficiency
0.000 0.544 0.456
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.544 0.456
D81.4 Nezelof's syndrome
0.000 0.544 0.456
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.544 0.456
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.544 0.456
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.544 0.456
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.544 0.456
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.544 0.456
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.544 0.456
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.544 0.456
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.544 0.456
D82.2 Immunodeficiency with short-limbed stature
0.000 0.544 0.456
D82.1 Di George's syndrome
0.000 0.544 0.456
D82.0 Wiskott-Aldrich syndrome
0.000 0.544 0.456
E51.2 Wernicke's encephalopathy
0.000 0.547 0.453
D89.3 Immune reconstitution syndrome
0.000 0.548 0.452
K90.3 Pancreatic steatorrhoea
0.000 0.549 0.451
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.549 0.451
K90.1 Tropical sprue
0.000 0.549 0.451
E51.9 Thiamine deficiency, unspecified
0.000 0.550 0.450
E51.8 Other manifestations of thiamine deficiency
0.000 0.550 0.450
E51.1 Beriberi
0.000 0.550 0.450
E24 Cushing's syndrome
0.000 0.552 0.448
L40.0 Psoriasis vulgaris
0.448 0.552 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.552 0.448
E50.8 Other manifestations of vitamin A deficiency
0.000 0.552 0.448
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.552 0.448
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.552 0.448
E50.5 Vitamin A deficiency with night blindness
0.000 0.552 0.448
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.552 0.448
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.552 0.448
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.552 0.448
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.552 0.448
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.552 0.448
E56.9 Vitamin deficiency, unspecified
0.000 0.552 0.448
E56.8 Deficiency of other vitamins
0.000 0.552 0.448
E56.1 Deficiency of vitamin K
0.000 0.552 0.448
E56.0 Deficiency of vitamin E
0.000 0.552 0.448
E63.9 Nutritional deficiency, unspecified
0.000 0.552 0.448
E63.8 Other specified nutritional deficiencies
0.000 0.552 0.448
E63.1 Imbalance of constituents of food intake
0.000 0.552 0.448
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.552 0.448
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.552 0.448
E64.8 Sequelae of other nutritional deficiencies
0.000 0.552 0.448
E64.3 Sequelae of rickets
0.000 0.552 0.448
E64.2 Sequelae of vitamin C deficiency
0.000 0.552 0.448
E64.1 Sequelae of vitamin A deficiency
0.000 0.552 0.448
E64.0 Sequelae of protein-energy malnutrition
0.000 0.552 0.448
E26 Hyperaldosteronism
0.000 0.552 0.447
E61.9 Deficiency of nutrient element, unspecified
0.000 0.557 0.442
E61.8 Deficiency of other specified nutrient elements
0.000 0.557 0.442
E61.7 Deficiency of multiple nutrient elements
0.000 0.557 0.442
E61.6 Vanadium deficiency
0.000 0.557 0.442
E61.5 Molybdenum deficiency
0.000 0.557 0.442
E61.4 Chromium deficiency
0.000 0.557 0.442
E61.3 Manganese deficiency
0.000 0.557 0.442
E61.0 Copper deficiency
0.000 0.557 0.442
E10.2 With renal complications
0.000 0.560 0.440
E16.2 Hypoglycaemia, unspecified
0.000 0.561 0.439
D69.1 Qualitative platelet defects
0.000 0.562 0.438
E10.1 With ketoacidosis
0.000 0.566 0.434
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.569 0.430
E65-E68 Obesity and other hyperalimentation
0.000 0.572 0.427
E30.9 Disorder of puberty, unspecified
0.000 0.573 0.427
E30.8 Other disorders of puberty
0.000 0.573 0.427
E30.1 Precocious puberty
0.000 0.573 0.427
E30.0 Delayed puberty
0.000 0.573 0.427
E31.9 Polyglandular dysfunction, unspecified
0.000 0.573 0.427
E31.8 Other polyglandular dysfunction
0.000 0.573 0.427
E31.1 Polyglandular hyperfunction
0.000 0.573 0.427
E31.0 Autoimmune polyglandular failure
0.000 0.573 0.427
E32.9 Disease of thymus, unspecified
0.000 0.573 0.427
E32.8 Other diseases of thymus
0.000 0.573 0.427
E32.1 Abscess of thymus
0.000 0.573 0.427
E32.0 Persistent hyperplasia of thymus
0.000 0.573 0.427
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.573 0.427
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.573 0.427
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.573 0.427
D89.1 Cryoglobulinaemia
0.000 0.581 0.419
E21.0 Primary hyperparathyroidism
0.000 0.581 0.419
E20.8 Other hypoparathyroidism
0.000 0.582 0.417
E20.1 Pseudohypoparathyroidism
0.000 0.582 0.417
E20.0 Idiopathic hypoparathyroidism
0.000 0.582 0.417
D83.8 Other common variable immunodeficiencies
0.000 0.583 0.417
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.583 0.417
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.583 0.417
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.583 0.417
D69.6 Thrombocytopenia, unspecified
0.000 0.583 0.417
E25.9 Adrenogenital disorder, unspecified
0.000 0.588 0.412
E25.8 Other adrenogenital disorders
0.000 0.588 0.412
L42 Pityriasis rosea
0.412 0.588 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.588 0.412
E10.3 With ophthalmic complications
0.000 0.593 0.407
E29.9 Testicular dysfunction, unspecified
0.000 0.594 0.406
E29.8 Other testicular dysfunction
0.000 0.594 0.406
E29.0 Testicular hyperfunction
0.000 0.594 0.406
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.595 0.405
E20.9 Hypoparathyroidism, unspecified
0.000 0.596 0.404
E28.3 Primary ovarian failure
0.000 0.599 0.401
L43.9 Lichen planus, unspecified
0.397 0.603 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.603 0.397
L44 Other papulosquamous disorders
0.396 0.604 0.000
L41 Parapsoriasis
0.396 0.604 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.396 0.604 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.605 0.395
E34.9 Endocrine disorder, unspecified
0.000 0.605 0.395
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.609 0.391
L43.0 Hypertrophic lichen planus
0.389 0.611 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.611 0.389
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.611 0.389
E16.4 Abnormal secretion of gastrin
0.000 0.611 0.389
E16.3 Increased secretion of glucagon
0.000 0.611 0.389
E10.0 With coma
0.000 0.612 0.387
E22 Hyperfunction of pituitary gland
0.000 0.618 0.382
E34.0 Carcinoid syndrome
0.000 0.619 0.381
D59 Acquired haemolytic anaemia
0.000 0.620 0.380
D80 Immunodeficiency with predominantly antibody defects
0.000 0.622 0.377
E10.7 With multiple complications
0.000 0.624 0.376
E29.1 Testicular hypofunction
0.000 0.624 0.376
D60-D64 Aplastic and other anaemias
0.000 0.625 0.375
E34.5 Androgen resistance syndrome
0.000 0.626 0.373
E34.4 Constitutional tall stature
0.000 0.626 0.373
E34.3 Short stature, not elsewhere classified
0.000 0.626 0.373
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.626 0.373
E34.1 Other hypersecretion of intestinal hormones
0.000 0.626 0.373
K90.8 Other intestinal malabsorption
0.000 0.627 0.372
E16.1 Other hypoglycaemia
0.000 0.636 0.364
D83.9 Common variable immunodeficiency, unspecified
0.000 0.636 0.363
D55 Anaemia due to enzyme disorders
0.000 0.637 0.363
D84.1 Defects in the complement system
0.000 0.637 0.363
E23 Hypofunction and other disorders of pituitary gland
0.000 0.637 0.363
D84.8 Other specified immunodeficiencies
0.000 0.638 0.361
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.638 0.361
E28.9 Ovarian dysfunction, unspecified
0.000 0.639 0.361
E28.8 Other ovarian dysfunction
0.000 0.639 0.361
E28.1 Androgen excess
0.000 0.639 0.361
E28.0 Oestrogen excess
0.000 0.639 0.361
E10.4 With neurological complications
0.000 0.642 0.358
E14 Unspecified diabetes mellitus
0.000 0.646 0.354
E10.5 With peripheral circulatory complications
0.000 0.648 0.352
E27.8 Other specified disorders of adrenal gland
0.001 0.651 0.348
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.651 0.349
E21.4 Other specified disorders of parathyroid gland
0.000 0.651 0.348
E21.2 Other hyperparathyroidism
0.000 0.651 0.348
K51.4 Pseudopolyposis of colon
0.000 0.654 0.346
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.654 0.345
E45 Retarded development following protein-energy malnutrition
0.000 0.654 0.345
E43 Unspecified severe protein-energy malnutrition
0.000 0.654 0.345
E42 Marasmic kwashiorkor
0.000 0.654 0.345
E41 Nutritional marasmus
0.000 0.654 0.345
E40 Kwashiorkor
0.000 0.654 0.345
D56 Thalassaemia
0.000 0.657 0.343
D68.9 Coagulation defect, unspecified
0.000 0.659 0.341
D57 Sickle-cell disorders
0.000 0.662 0.338
E10.6 With other specified complications
0.000 0.663 0.336
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.664 0.336
L43.3 Subacute (active) lichen planus
0.332 0.668 0.000
L43.2 Lichenoid drug reaction
0.332 0.668 0.000
L43.1 Bullous lichen planus
0.332 0.668 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.669 0.331
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.676 0.324
E24.8 Other Cushing's syndrome
0.000 0.678 0.321
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.678 0.321
E24.3 Ectopic ACTH syndrome
0.000 0.678 0.321
E24.1 Nelson's syndrome
0.000 0.678 0.321
E26.8 Other hyperaldosteronism
0.000 0.679 0.321
E26.1 Secondary hyperaldosteronism
0.000 0.679 0.321
E61.1 Iron deficiency
0.000 0.680 0.320
E14.3 With ophthalmic complications
0.000 0.681 0.319
E24.2 Drug-induced Cushing's syndrome
0.000 0.682 0.318
D64 Other anaemias
0.000 0.690 0.310
E65 Localised adiposity
0.000 0.692 0.308
E67 Other hyperalimentation
0.000 0.693 0.307
E68 Sequelae of hyperalimentation
0.000 0.693 0.307
E26.9 Hyperaldosteronism, unspecified
0.000 0.703 0.297
D59.1 Other autoimmune haemolytic anaemias
0.000 0.705 0.295
E24.0 Pituitary-dependent Cushing's disease
0.000 0.708 0.292
L41.9 Parapsoriasis, unspecified
0.284 0.716 0.000
L41.8 Other parapsoriasis
0.284 0.716 0.000
L41.5 Retiform parapsoriasis
0.284 0.716 0.000
L41.4 Large plaque parapsoriasis
0.284 0.716 0.000
L41.3 Small plaque parapsoriasis
0.284 0.716 0.000
L41.2 Lymphomatoid papulosis
0.284 0.716 0.000
L41.1 Pityriasis lichenoides chronica
0.284 0.716 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.284 0.716 0.000
L44.9 Papulosquamous disorder, unspecified
0.284 0.716 0.000
L44.8 Other specified papulosquamous disorders
0.284 0.716 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.284 0.716 0.000
L44.3 Lichen ruber moniliformis
0.284 0.716 0.000
L44.2 Lichen striatus
0.284 0.716 0.000
L44.1 Lichen nitidus
0.284 0.716 0.000
L44.0 Pityriasis rubra pilaris
0.284 0.716 0.000
E12.9 Without complications
0.000 0.716 0.283
E12.8 With unspecified complications
0.000 0.716 0.283
E12.7 With multiple complications
0.000 0.716 0.283
E12.6 With other specified complications
0.000 0.716 0.283
E12.5 With peripheral circulatory complications
0.000 0.716 0.283
E12.4 With neurological complications
0.000 0.716 0.283
E12.3 With ophthalmic complications
0.000 0.716 0.283
E12.2 With renal complications
0.000 0.716 0.283
E12.1 With ketoacidosis
0.000 0.716 0.283
E12.0 With coma
0.000 0.716 0.283
E14.1 With ketoacidosis
0.000 0.720 0.280
D58 Other hereditary haemolytic anaemias
0.000 0.724 0.276
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.726 0.274
E22.8 Other hyperfunction of pituitary gland
0.000 0.726 0.274
D59.8 Other acquired haemolytic anaemias
0.000 0.727 0.273
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.727 0.273
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.727 0.273
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.727 0.273
D59.3 Haemolytic-uraemic syndrome
0.000 0.727 0.273
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.727 0.273
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.727 0.273
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.729 0.271
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.729 0.271
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.729 0.271
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.729 0.271
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.729 0.271
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.731 0.269
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.733 0.266
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.739 0.260
D55.8 Other anaemias due to enzyme disorders
0.000 0.739 0.260
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.739 0.260
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.739 0.260
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.739 0.260
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.739 0.260
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.740 0.260
E23.1 Drug-induced hypopituitarism
0.000 0.740 0.260
D56.1 Beta thalassaemia
0.000 0.742 0.258
D64.8 Other specified anaemias
0.000 0.743 0.257
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.744 0.256
E14.2 Withrenal complications
0.000 0.744 0.256
E23.6 Other disorders of pituitary gland
0.000 0.745 0.255
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.746 0.254
E14.7 With multiple complications
0.000 0.746 0.254
E14.0 With coma
0.000 0.746 0.254
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.748 0.251
E04 Other non-toxic goitre
0.000 0.751 0.249
E23.7 Disorder of pituitary gland, unspecified
0.000 0.752 0.248
E44.1 Mild protein-energy malnutrition
0.000 0.752 0.248
E44.0 Moderate protein-energy malnutrition
0.000 0.752 0.248
M35.3 Polymyalgia rheumatica
0.000 0.752 0.248
E34.8 Other specified endocrine disorders
0.001 0.753 0.247
E13 Other specified diabetes mellitus
0.001 0.753 0.246
E14.8 With unspecified complications
0.000 0.754 0.246
D56.9 Thalassaemia, unspecified
0.000 0.754 0.246
D56.8 Other thalassaemias
0.000 0.754 0.246
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.000 0.754 0.246
D56.2 Delta-beta thalassaemia
0.000 0.754 0.246
D56.0 Alpha thalassaemia
0.000 0.754 0.246
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.756 0.244
D57.8 Other sickle-cell disorders
0.000 0.757 0.242
D57.3 Sickle-cell trait
0.000 0.757 0.242
D57.2 Double heterozygous sickling disorders
0.000 0.757 0.242
D57.0 Sickle-cell anaemia with crisis
0.000 0.757 0.242
L43.8 Other lichen planus
0.242 0.758 0.000
E10.8 With unspecified complications
0.001 0.759 0.241
E14.4 With neurological complications
0.000 0.759 0.241
E14.6 With other specified complications
0.000 0.760 0.240
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.762 0.238
D64.9 Anaemia, unspecified
0.000 0.766 0.234
G36 Other acute disseminated demyelination
0.000 0.768 0.232
E24.9 Cushing's syndrome, unspecified
0.000 0.768 0.231
E22.0 Acromegaly and pituitary gigantism
0.000 0.770 0.229
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.001 0.772 0.227
D84.9 Immunodeficiency, unspecified
0.001 0.774 0.226
D64.4 Congenital dyserythropoietic anaemia
0.000 0.778 0.222
D64.3 Other sideroblastic anaemias
0.000 0.778 0.222
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.778 0.222
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.778 0.222
D64.0 Hereditary sideroblastic anaemia
0.000 0.778 0.222
E67.8 Other specified hyperalimentation
0.000 0.780 0.220
E67.3 Hypervitaminosis D
0.000 0.780 0.220
E67.2 Megavitamin-B6 syndrome
0.000 0.780 0.220
E67.1 Hypercarotenaemia
0.000 0.780 0.220
E67.0 Hypervitaminosis A
0.000 0.780 0.220
D57.1 Sickle-cell anaemia without crisis
0.000 0.782 0.217
E26.0 Primary hyperaldosteronism
0.001 0.784 0.215
E23.2 Diabetes insipidus
0.000 0.785 0.214
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.789 0.211
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.789 0.211
E70-E90 Metabolic disorders
0.000 0.789 0.211
D56.3 Thalassaemia trait
0.000 0.790 0.210
D61 Other aplastic anaemias
0.000 0.795 0.205
E86 Volume depletion
0.000 0.796 0.204
E14.5 With peripheral circulatory complications
0.000 0.797 0.203
G37 Other demyelinating diseases of central nervous system
0.000 0.798 0.202
E22.1 Hyperprolactinaemia
0.000 0.798 0.202
D58.8 Other specified hereditary haemolytic anaemias
0.000 0.802 0.198
D58.1 Hereditary elliptocytosis
0.000 0.802 0.198
D58.0 Hereditary spherocytosis
0.000 0.802 0.198
E46 Unspecified protein-energy malnutrition
0.000 0.806 0.194
D60.9 Acquired pure red cell aplasia, unspecified
0.000 0.807 0.193
D60.8 Other acquired pure red cell aplasias
0.000 0.807 0.193
D60.1 Transient acquired pure red cell aplasia
0.000 0.807 0.193
D60.0 Chronic acquired pure red cell aplasia
0.000 0.807 0.193
D76.3 Other histiocytosis syndromes
0.000 0.808 0.192
D62 Acute posthaemorrhagic anaemia
0.000 0.808 0.192
K51.2 Ulcerative (chronic) proctitis
0.000 0.810 0.190
E28.2 Polycystic ovarian syndrome
0.000 0.820 0.179
E04.8 Other specified non-toxic goitre
0.000 0.821 0.179
E13.8 With unspecified complications
0.001 0.823 0.176
E13.7 With multiple complications
0.001 0.823 0.176
E13.6 With other specified complications
0.001 0.823 0.176
E13.5 With peripheral circulatory complications
0.001 0.823 0.176
E13.4 With neurological complications
0.001 0.823 0.176
E13.2 With renal complications
0.001 0.823 0.176
E13.1 With ketoacidosis
0.001 0.823 0.176
E13.0 With coma
0.001 0.823 0.176
D58.2 Other haemoglobinopathies
0.001 0.829 0.171
D74 Methaemoglobinaemia
0.000 0.829 0.171
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.829 0.171
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.829 0.171
E73 Lactose intolerance
0.000 0.831 0.169

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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