TreeWAS – Variant ID: rs41291798

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	1.000
E10.9 Without complications	0.000	1.000
K90.0 Coeliac disease	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	1.000
E10-E14 Diabetes mellitus	0.000	1.000
J30-J39 Other diseases of upper respiratory tract	0.000	1.000
Chapter X Diseases of the respiratory system	0.000	1.000
J33 Nasal polyp	0.000	1.000
E11 Non-insulin-dependent diabetes mellitus	0.000	1.000
G35 Multiple sclerosis	0.001	0.999
Chapter IV Endocrine, nutritional and metabolic diseases	0.001	0.999
E10.3 With ophthalmic complications	0.001	0.999
J32 Chronic sinusitis	0.001	0.999
E11.9 Without complications	0.001	0.999
# Top node	0.002	0.998
G35-G37 Demyelinating diseases of the central nervous system	0.002	0.998
J32.9 Chronic sinusitis, unspecified	0.002	0.998
Chapter VI Diseases of the nervous system	0.004	0.996
J33.9 Nasal polyp, unspecified	0.006	0.994
E10.1 With ketoacidosis	0.008	0.992
Chapter XII Diseases of the skin and subcutaneous tissue	0.014	0.986
L00-L08 Infections of the skin and subcutaneous tissue	0.015	0.985
J33.8 Other polyp of sinus	0.020	0.980
E10.4 With neurological complications	0.020	0.980
L02 Cutaneous abscess, furuncle and carbuncle	0.021	0.979
J33.0 Polyp of nasal cavity	0.022	0.978
K90 Intestinal malabsorption	0.024	0.976
J40-J47 Chronic lower respiratory diseases	0.025	0.975
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.025	0.975
M06 Other rheumatoid arthritis	0.028	0.972
J90-J94 Other diseases of pleura	0.032	0.968
L03 Cellulitis	0.034	0.966
J44 Other chronic obstructive pulmonary disease	0.038	0.962
L03.1 Cellulitis of other parts of limb	0.038	0.962
K90-K93 Other diseases of the digestive system	0.040	0.960
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.045	0.955
Chapter XI Diseases of the digestive system	0.048	0.952
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.050	0.950
Chapter I Certain infectious and parasitic diseases	0.059	0.941
B95-B98 Bacterial, viral and other infectious agents	0.062	0.938
J93 Pneumothorax	0.064	0.936
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.066	0.934
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.068	0.932
E16 Other disorders of pancreatic internal secretion	0.076	0.924
M05-M14 Inflammatory polyarthropathies	0.078	0.922
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.078	0.922
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.087	0.913
E11.5 With peripheral circulatory complications	0.090	0.910
E16.2 Hypoglycaemia, unspecified	0.096	0.904
M05 Seropositive rheumatoid arthritis	0.099	0.901
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.099	0.901
K70-K77 Diseases of liver	0.101	0.899
J47 Bronchiectasis	0.103	0.897
L40-L45 Papulosquamous disorders	0.105	0.895
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.106	0.894
M05.9 Seropositive rheumatoid arthritis, unspecified	0.114	0.886
E50-E64 Other nutritional deficiencies	0.115	0.885
J93.9 Pneumothorax, unspecified	0.117	0.883
J44.8 Other specified chronic obstructive pulmonary disease	0.121	0.879
M06.0 Seronegative rheumatoid arthritis	0.122	0.878
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.122	0.878
J00-J06 Acute upper respiratory infections	0.125	0.875
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.126	0.874
L43 Lichen planus	0.131	0.869
J32.4 Chronic pansinusitis	0.134	0.866
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.141	0.859
K76 Other diseases of liver	0.144	0.856
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.148	0.852
L43.9 Lichen planus, unspecified	0.149	0.851
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.152	0.848
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.154	0.846
E11.1 With ketoacidosis	0.161	0.839
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.163	0.837
G80-G83 Cerebral palsy and other paralytic syndromes	0.164	0.836
K76.8 Other specified diseases of liver	0.166	0.834
J39 Other diseases of upper respiratory tract	0.170	0.830
K35-K38 Diseases of appendix	0.170	0.830
Chapter XXII Codes for special purposes	0.172	0.828
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.173	0.827
B15-B19 Viral hepatitis	0.174	0.826
J90 Pleural effusion, not elsewhere classified	0.174	0.826
E40-E46 Malnutrition	0.177	0.823
E14 Unspecified diabetes mellitus	0.178	0.822
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.178	0.822
G37 Other demyelinating diseases of central nervous system	0.182	0.818
G70-G73 Diseases of myoneural junction and muscle	0.182	0.818
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.183	0.817
J93.1 Other spontaneous pneumothorax	0.188	0.811
E11.0 With coma	0.192	0.808
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.193	0.807
J00 Acute nasopharyngitis [common cold]	0.194	0.806
E11.3 With ophthalmic complications	0.195	0.805
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.197	0.803
K74 Fibrosis and cirrhosis of liver	0.198	0.802
J32.8 Other chronic sinusitis	0.198	0.802
J37 Chronic laryngitis and laryngotracheitis	0.200	0.800
J60-J70 Lung diseases due to external agents	0.200	0.800
E13 Other specified diabetes mellitus	0.201	0.799
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.206	0.794
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.209	0.791
K37 Unspecified appendicitis	0.209	0.791
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.211	0.789
J94 Other pleural conditions	0.218	0.782
J46 Status asthmaticus	0.221	0.779
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.227	0.773
L50-L54 Urticaria and erythema	0.228	0.772
E53 Deficiency of other B group vitamins	0.228	0.772
L03.8 Cellulitis of other sites	0.233	0.767
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.234	0.766
E70-E90 Metabolic disorders	0.236	0.764
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.243	0.757
G81 Hemiplegia	0.243	0.757
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.244	0.756
J32.2 Chronic ethmoidal sinusitis	0.244	0.756
J36 Peritonsillar abscess	0.248	0.752
J44.9 Chronic obstructive pulmonary disease, unspecified	0.257	0.743
J06 Acute upper respiratory infections of multiple and unspecified sites	0.261	0.739
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.262	0.738
G70 Myasthenia gravis and other myoneural disorders	0.264	0.736
J95-J99 Other diseases of the respiratory system	0.265	0.735
K74.3 Primary biliary cirrhosis	0.269	0.731
E83 Disorders of mineral metabolism	0.273	0.727
E11.4 With neurological complications	0.274	0.726
E14.3 With ophthalmic complications	0.279	0.721
B18 Chronic viral hepatitis	0.279	0.721
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.280	0.720
K76.0 Fatty (change of) liver, not elsewhere classified	0.280	0.720
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.281	0.718
M06.98 Rheumatoid arthritis, unspecified (Other)	0.283	0.717
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.283	0.717
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.283	0.717
E10.8 With unspecified complications	0.283	0.717
E10.7 With multiple complications	0.283	0.717
E10.6 With other specified complications	0.283	0.717
E10.5 With peripheral circulatory complications	0.283	0.717
E10.2 With renal complications	0.283	0.717
E10.0 With coma	0.283	0.717
E12 Malnutrition-related diabetes mellitus	0.283	0.717
J33.1 Polypoid sinus degeneration	0.283	0.717
E11.7 With multiple complications	0.283	0.717
J32.3 Chronic sphenoidal sinusitis	0.283	0.716
J32.1 Chronic frontal sinusitis	0.283	0.716
E83.1 Disorders of iron metabolism	0.284	0.716
Chapter XVI Certain conditions originating in the perinatal period	0.284	0.716
G36 Other acute disseminated demyelination	0.285	0.715
J91 Pleural effusion in conditions classified elsewhere	0.286	0.714
L08 Other local infections of skin and subcutaneous tissue	0.286	0.714
E11.6 With other specified complications	0.288	0.712
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.289	0.711
G37.9 Demyelinating disease of central nervous system, unspecified	0.289	0.711
L04 Acute lymphadenitis	0.293	0.706
L01 Impetigo	0.293	0.706
L00 Staphylococcal scalded skin syndrome	0.293	0.706
B20-B24 Human immunodeficiency virus [HIV] disease	0.295	0.705
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.297	0.703
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.298	0.702
K90.8 Other intestinal malabsorption	0.300	0.700
K90.3 Pancreatic steatorrhoea	0.300	0.700
K90.2 Blind loop syndrome, not elsewhere classified	0.300	0.700
K90.1 Tropical sprue	0.300	0.700
G81.9 Hemiplegia, unspecified	0.300	0.700
J41 Simple and mucopurulent chronic bronchitis	0.301	0.699
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.301	0.699
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.302	0.698
J09-J18 Influenza and pneumonia	0.302	0.698
M06.8 Other specified rheumatoid arthritis	0.303	0.697
M06.3 Rheumatoid nodule	0.303	0.697
M06.2 Rheumatoid bursitis	0.303	0.697
M06.1 Adult-onset Still's disease	0.303	0.697
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.303	0.697
J39.2 Other diseases of pharynx	0.303	0.697
E46 Unspecified protein-energy malnutrition	0.303	0.697
J93.8 Other pneumothorax	0.304	0.695
E53.8 Deficiency of other specified B group vitamins	0.310	0.690
E11.8 With unspecified complications	0.311	0.689
K93 Disorders of other digestive organs in diseases classified elsewhere	0.311	0.688
J32.0 Chronic maxillary sinusitis	0.313	0.687
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.313	0.687
E15 Nondiabetic hypoglycaemic coma	0.315	0.685
K72 Hepatic failure, not elsewhere classified	0.317	0.683
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.317	0.683
E61 Deficiency of other nutrient elements	0.318	0.682
M14 Arthropathies in other diseases classified elsewhere	0.321	0.679
A80-A89 Viral infections of the central nervous system	0.322	0.678
G70.0 Myasthenia gravis	0.323	0.677
B50-B64 Protozoal diseases	0.325	0.675
B85-B89 Pediculosis, acariasis and other infestations	0.326	0.674
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.326	0.674
A75-A79 Rickettsioses	0.326	0.674
A70-A74 Other diseases caused by chlamydiae	0.326	0.674
A20-A28 Certain zoonotic bacterial diseases	0.326	0.674
J93.0 Spontaneous tension pneumothorax	0.329	0.671
L03.0 Cellulitis of finger and toe	0.335	0.665
E55 Vitamin D deficiency	0.337	0.663
K73 Chronic hepatitis, not elsewhere classified	0.337	0.663
E16.9 Disorder of pancreatic internal secretion, unspecified	0.337	0.663
E16.8 Other specified disorders of pancreatic internal secretion	0.337	0.663
E16.4 Abnormal secretion of gastrin	0.337	0.663
E16.3 Increased secretion of glucagon	0.337	0.663
E16.0 Drug-induced hypoglycaemia without coma	0.337	0.663
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.337	0.663
M11 Other crystal arthropathies	0.338	0.662
M09 Juvenile arthritis in diseases classified elsewhere	0.339	0.661
M08 Juvenile arthritis	0.339	0.661
L10-L14 Bullous disorders	0.341	0.659
J37.0 Chronic laryngitis	0.344	0.656
G30-G32 Other degenerative diseases of the nervous system	0.345	0.655
E13.9 Without complications	0.345	0.655
M06.4 Inflammatory polyarthropathy	0.345	0.654
G00-G09 Inflammatory diseases of the central nervous system	0.346	0.654
B90-B94 Sequelae of infectious and parasitic diseases	0.346	0.654
E87 Other disorders of fluid, electrolyte and acid-base balance	0.348	0.652
G11 Hereditary ataxia	0.353	0.647
M05.8 Other seropositive rheumatoid arthritis	0.354	0.646
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.354	0.646
M05.2 Rheumatoid vasculitis	0.354	0.646
M05.1 Rheumatoid lung disease	0.354	0.646
M05.0 Felty's syndrome	0.354	0.646
K36 Other appendicitis	0.354	0.646
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.354	0.646
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.354	0.646
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.354	0.646
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.355	0.645
K77 Liver disorders in diseases classified elsewhere	0.355	0.644
K71 Toxic liver disease	0.355	0.644
K91.4 Colostomy and enterostomy malfunction	0.357	0.643
J31.0 Chronic rhinitis	0.358	0.642
G12 Spinal muscular atrophy and related syndromes	0.358	0.642
G83 Other paralytic syndromes	0.358	0.641
L44 Other papulosquamous disorders	0.359	0.641
L41 Parapsoriasis	0.359	0.641
L45 Papulosquamous disorders in diseases classified elsewhere	0.359	0.641
L42 Pityriasis rosea	0.359	0.641
J06.9 Acute upper respiratory infection, unspecified	0.360	0.640
A65-A69 Other spirochaetal diseases	0.360	0.640
J80-J84 Other respiratory diseases principally affecting the interstitium	0.360	0.640
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.360	0.639
J30 Vasomotor and allergic rhinitis	0.361	0.639
L53 Other erythematous conditions	0.362	0.638
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.362	0.638
J04 Acute laryngitis and tracheitis	0.362	0.638
B65-B83 Helminthiases	0.363	0.637
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.364	0.635
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.364	0.635
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.364	0.635
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.364	0.635
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.364	0.635
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.364	0.635
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.364	0.635
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.364	0.635
E64 Sequelae of malnutrition and other nutritional deficiencies	0.365	0.635
E63 Other nutritional deficiencies	0.365	0.635
E56 Other vitamin deficiencies	0.365	0.635
E51 Thiamine deficiency	0.365	0.635
E50 Vitamin A deficiency	0.365	0.635
E60 Dietary zinc deficiency	0.365	0.635
E59 Dietary selenium deficiency	0.365	0.635
E58 Dietary calcium deficiency	0.365	0.635
E54 Ascorbic acid deficiency	0.365	0.635
E52 Niacin deficiency [pellagra]	0.365	0.635
E16.1 Other hypoglycaemia	0.365	0.634
B17 Other acute viral hepatitis	0.367	0.633
B18.2 Chronic viral hepatitis C	0.369	0.631
K65-K67 Diseases of peritoneum	0.370	0.630
J69 Pneumonitis due to solids and liquids	0.370	0.630
M06.08 Seronegative rheumatoid arthritis (Other)	0.370	0.630
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.370	0.630
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.370	0.630
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.370	0.630
M06.04 Seronegative rheumatoid arthritis (Hand)	0.370	0.630
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.370	0.630
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.370	0.630
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.370	0.630
E87.1 Hypo-osmolality and hyponatraemia	0.371	0.629
J35 Chronic diseases of tonsils and adenoids	0.371	0.629
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.373	0.627
L43.8 Other lichen planus	0.377	0.623
L43.3 Subacute (active) lichen planus	0.377	0.623
L43.2 Lichenoid drug reaction	0.377	0.623
L43.1 Bullous lichen planus	0.377	0.623
L43.0 Hypertrophic lichen planus	0.377	0.623
A50-A64 Infections with a predominantly sexual mode of transmission	0.378	0.622
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.378	0.622
E73 Lactose intolerance	0.378	0.622
B16 Acute hepatitis B	0.379	0.620
J94.2 Haemothorax	0.380	0.620
B99-B99 Other infectious diseases	0.381	0.619
K74.5 Biliary cirrhosis, unspecified	0.381	0.619
J39.8 Other specified diseases of upper respiratory tract	0.384	0.616
K76.7 Hepatorenal syndrome	0.386	0.614
K76.5 Hepatic veno-occlusive disease	0.386	0.614
K76.4 Peliosis hepatis	0.386	0.614
K76.3 Infarction of liver	0.386	0.614
K76.2 Central haemorrhagic necrosis of liver	0.386	0.614
K76.1 Chronic passive congestion of liver	0.386	0.614
L08.8 Other specified local infections of skin and subcutaneous tissue	0.387	0.613
J01 Acute sinusitis	0.387	0.613
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.388	0.612
K91.9 Postprocedural disorder of digestive system, unspecified	0.392	0.608
K91.5 Postcholecystectomy syndrome	0.392	0.608
K91.2 Postsurgical malabsorption, not elsewhere classified	0.392	0.608
A15-A19 Tuberculosis	0.393	0.607
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.394	0.606
M12 Other specific arthropathies	0.394	0.606
J31.2 Chronic pharyngitis	0.396	0.604
J94.8 Other specified pleural conditions	0.399	0.601
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.399	0.601
K91.1 Postgastric surgery syndromes	0.402	0.598
J39.9 Disease of upper respiratory tract, unspecified	0.405	0.595
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified	0.405	0.595
J39.1 Other abscess of pharynx	0.405	0.595
J39.0 Retropharyngeal and parapharyngeal abscess	0.405	0.595
J10 Influenza due to identified influenza virus	0.405	0.595
U88 Agent resistant to multiple antibiotics	0.407	0.593
M00-M03 Infectious arthropathies	0.407	0.593
G83.4 Cauda equina syndrome	0.407	0.593
B19 Unspecified viral hepatitis	0.407	0.592
B02 Zoster [herpes zoster]	0.408	0.592
E44 Protein-energy malnutrition of moderate and mild degree	0.410	0.590
E45 Retarded development following protein-energy malnutrition	0.410	0.590
E43 Unspecified severe protein-energy malnutrition	0.410	0.590
E42 Marasmic kwashiorkor	0.410	0.590
E41 Nutritional marasmus	0.410	0.590
E40 Kwashiorkor	0.410	0.590
E14.8 With unspecified complications	0.410	0.590
E14.7 With multiple complications	0.410	0.590
E14.6 With other specified complications	0.410	0.590
E14.5 With peripheral circulatory complications	0.410	0.590
E14.4 With neurological complications	0.410	0.590
E14.2 Withrenal complications	0.410	0.590
E14.1 With ketoacidosis	0.410	0.590
E14.0 With coma	0.410	0.590
L05 Pilonidal cyst	0.411	0.589
J20-J22 Other acute lower respiratory infections	0.412	0.588
J40 Bronchitis, not specified as acute or chronic	0.412	0.588
G37.8 Other specified demyelinating diseases of central nervous system	0.413	0.587
G37.5 Concentric sclerosis [Balo]	0.413	0.587
G37.4 Subacute necrotising myelitis	0.413	0.587
G37.2 Central pontine myelinolysis	0.413	0.587
G37.1 Central demyelination of corpus callosum	0.413	0.587
G37.0 Diffuse sclerosis	0.413	0.587
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.413	0.586
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere	0.414	0.586
G14 Postpolio syndrome	0.414	0.586
G10 Huntington's disease	0.414	0.586
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.415	0.585
B25-B34 Other viral diseases	0.416	0.584
L03.3 Cellulitis of trunk	0.417	0.583
L03.9 Cellulitis, unspecified	0.418	0.582
J95 Postprocedural respiratory disorders, not elsewhere classified	0.421	0.579
J31.1 Chronic nasopharyngitis	0.424	0.576
B15 Acute hepatitis A	0.424	0.576
K74.4 Secondary biliary cirrhosis	0.425	0.575
K74.2 Hepatic fibrosis with hepatic sclerosis	0.425	0.575
K74.1 Hepatic sclerosis	0.425	0.575
G40-G47 Episodic and paroxysmal disorders	0.425	0.575
J43 Emphysema	0.425	0.575
J70 Respiratory conditions due to other external agents	0.427	0.573
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.427	0.573
J66 Airway disease due to specific organic dust	0.427	0.573
J63 Pneumoconiosis due to other inorganic dusts	0.427	0.573
J62 Pneumoconiosis due to dust containing silica	0.427	0.573
J65 Pneumoconiosis associated with tuberculosis	0.427	0.573
J64 Unspecified pneumoconiosis	0.427	0.573
J60 Coalworker's pneumoconiosis	0.427	0.573
J37.1 Chronic laryngotracheitis	0.427	0.573
E13.8 With unspecified complications	0.427	0.573
E13.7 With multiple complications	0.427	0.573
E13.6 With other specified complications	0.427	0.573
E13.5 With peripheral circulatory complications	0.427	0.573
E13.4 With neurological complications	0.427	0.573
E13.3 With ophthalmic complications	0.427	0.573
E13.2 With renal complications	0.427	0.573
E13.1 With ketoacidosis	0.427	0.573
E13.0 With coma	0.427	0.573
B00 Herpesviral [herpes simplex] infections	0.428	0.572
J67 Hypersensitivity pneumonitis due to organic dust	0.432	0.568
E87.0 Hyperosmolality and hypernatraemia	0.432	0.568
J14 Pneumonia due to Haemophilus influenzae	0.436	0.564
E74 Other disorders of carbohydrate metabolism	0.438	0.562
J94.9 Pleural condition, unspecified	0.439	0.561
J94.1 Fibrothorax	0.439	0.561
J94.0 Chylous effusion	0.439	0.561
L53.9 Erythematous condition, unspecified	0.444	0.556
K74.6 Other and unspecified cirrhosis of liver	0.444	0.556
G72 Other myopathies	0.444	0.556
G82 Paraplegia and tetraplegia	0.445	0.555
L54 Erythema in diseases classified elsewhere	0.446	0.553
L52 Erythema nodosum	0.446	0.553
E53.9 Vitamin B deficiency, unspecified	0.447	0.553
E53.1 Pyridoxine deficiency	0.447	0.553
E53.0 Riboflavin deficiency	0.447	0.553
J42 Unspecified chronic bronchitis	0.447	0.552
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.448	0.552
K74.0 Hepatic fibrosis	0.449	0.551
B18.1 Chronic viral hepatitis B without delta-agent	0.449	0.551
E89.3 Postprocedural hypopituitarism	0.449	0.551
G45 Transient cerebral ischaemic attacks and related syndromes	0.450	0.550
E84 Cystic fibrosis	0.452	0.547
E79 Disorders of purine and pyrimidine metabolism	0.452	0.547
E77 Disorders of glycoprotein metabolism	0.452	0.547
E76 Disorders of glycosaminoglycan metabolism	0.452	0.547
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.452	0.547
E72 Other disorders of amino-acid metabolism	0.452	0.547
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.452	0.547
E70 Disorders of aromatic amino-acid metabolism	0.452	0.547
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.452	0.547
B97 Viral agents as the cause of diseases classified to other chapters	0.453	0.547
K91.3 Postoperative intestinal obstruction	0.453	0.547
K90.9 Intestinal malabsorption, unspecified	0.453	0.546
M10 Gout	0.455	0.545
K38 Other diseases of appendix	0.456	0.544
G81.1 Spastic hemiplegia	0.457	0.542
G81.0 Flaccid hemiplegia	0.457	0.542
L50 Urticaria	0.458	0.542
K72.9 Hepatic failure, unspecified	0.458	0.542
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.458	0.541
J35.8 Other chronic diseases of tonsils and adenoids	0.463	0.537
E61.1 Iron deficiency	0.463	0.536
B24 Unspecified human immunodeficiency virus [HIV] disease	0.464	0.535
L51 Erythema multiforme	0.466	0.534
K91.0 Vomiting following gastro-intestinal surgery	0.468	0.531
J06.8 Other acute upper respiratory infections of multiple sites	0.470	0.529
J06.0 Acute laryngopharyngitis	0.470	0.529
G45.9 Transient cerebral ischaemic attack, unspecified	0.471	0.529
E14.9 Without complications	0.471	0.529
G70.9 Myoneural disorder, unspecified	0.472	0.527
G70.8 Other specified myoneural disorders	0.472	0.527
G70.2 Congenital and developmental myasthenia	0.472	0.527
G70.1 Toxic myoneural disorders	0.472	0.527
J96 Respiratory failure, not elsewhere classified	0.473	0.527
A87 Viral meningitis	0.473	0.527
G11.9 Hereditary ataxia, unspecified	0.474	0.526
U89 Agent resistant to other and unspecified antibiotics	0.474	0.526
G63 Polyneuropathy in diseases classified elsewhere	0.476	0.524
E83.9 Disorder of mineral metabolism, unspecified	0.478	0.521
E83.8 Other disorders of mineral metabolism	0.478	0.521
E83.2 Disorders of zinc metabolism	0.478	0.521
E83.0 Disorders of copper metabolism	0.478	0.521
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.479	0.521
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.480	0.520
E73.9 Lactose intolerance, unspecified	0.480	0.520
J13 Pneumonia due to Streptococcus pneumoniae	0.480	0.520
B18.9 Chronic viral hepatitis, unspecified	0.483	0.517
B18.8 Other chronic viral hepatitis	0.483	0.517
B18.0 Chronic viral hepatitis B with delta-agent	0.483	0.517
E89.2 Postprocedural hypoparathyroidism	0.483	0.517
G12.2 Motor neuron disease	0.484	0.516
E12.9 Without complications	0.486	0.514
E12.8 With unspecified complications	0.486	0.514
E12.7 With multiple complications	0.486	0.514
E12.6 With other specified complications	0.486	0.514
E12.5 With peripheral circulatory complications	0.486	0.514
E12.4 With neurological complications	0.486	0.514
E12.3 With ophthalmic complications	0.486	0.514
E12.2 With renal complications	0.486	0.514
E12.1 With ketoacidosis	0.486	0.514
E12.0 With coma	0.486	0.514
P90-P96 Other disorders originating in the perinatal period	0.487	0.513
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.487	0.513
P75-P78 Digestive system disorders of fetus and newborn	0.487	0.513
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.487	0.513
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.487	0.513
P35-P39 Infections specific to the perinatal period	0.487	0.513
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.487	0.513
P10-P15 Birth trauma	0.487	0.513
P05-P08 Disorders related to length of gestation and fetal growth	0.487	0.513
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.487	0.513
G36.9 Acute disseminated demyelination, unspecified	0.487	0.513
G36.8 Other specified acute disseminated demyelination	0.487	0.513
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.487	0.513
G36.0 Neuromyelitis optica [Devic]	0.487	0.513
L08.1 Erythrasma	0.488	0.512
L08.0 Pyoderma	0.488	0.512
J03 Acute tonsillitis	0.488	0.511
M07 Psoriatic and enteropathic arthropathies	0.489	0.510
J85 Abscess of lung and mediastinum	0.490	0.510
E88 Other metabolic disorders	0.490	0.510
B02.9 Zoster without complication	0.490	0.510
J69.0 Pneumonitis due to food and vomit	0.491	0.509
J99 Respiratory disorders in diseases classified elsewhere	0.491	0.508
U80 Agent resistant to penicillin and related antibiotics	0.492	0.508
L01.1 Impetiginisation of other dermatoses	0.493	0.507
L01.0 Impetigo [any organism] [any site]	0.493	0.507
L04.9 Acute lymphadenitis, unspecified	0.493	0.507
L04.8 Acute lymphadenitis of other sites	0.493	0.507
L04.3 Acute lymphadenitis of lower limb	0.493	0.507
L04.2 Acute lymphadenitis of upper limb	0.493	0.507
L04.1 Acute lymphadenitis of trunk	0.493	0.507
L04.0 Acute lymphadenitis of face, head and neck	0.493	0.507
B23 Human immunodeficiency virus [HIV] disease resulting in other conditions	0.495	0.505
B22 Human immunodeficiency virus [HIV] disease resulting in other specified diseases	0.495	0.505
B21 Human immunodeficiency virus [HIV] disease resulting in malignant neoplasms	0.495	0.505
B20 Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases	0.495	0.505
J86 Pyothorax	0.496	0.504
M14.6 Neuropathic arthropathy	0.496	0.504
E55.9 Vitamin D deficiency, unspecified	0.496	0.504
G71 Primary disorders of muscles	0.498	0.502

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations