TreeWAS – Variant ID: rs4129601

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I50.9 Heart failure, unspecified	0.241	0.759	0.000
I50 Heart failure	0.241	0.759	0.000
I50.0 Congestive heart failure	0.240	0.760	0.000
I50.1 Left ventricular failure	0.227	0.773	0.000
E10.3 With ophthalmic complications	0.017	0.983	0.000
E10 Insulin-dependent diabetes mellitus	0.016	0.984	0.000
E10.1 With ketoacidosis	0.015	0.985	0.000
E10.4 With neurological complications	0.014	0.986	0.000
E10-E14 Diabetes mellitus	0.013	0.987	0.000
E10.8 With unspecified complications	0.012	0.988	0.000
E10.7 With multiple complications	0.012	0.988	0.000
E10.6 With other specified complications	0.012	0.988	0.000
E10.5 With peripheral circulatory complications	0.012	0.988	0.000
E10.2 With renal complications	0.012	0.988	0.000
E10.0 With coma	0.012	0.988	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.011	0.989	0.000
E14 Unspecified diabetes mellitus	0.011	0.989	0.000
E10.9 Without complications	0.010	0.990	0.000
E87.7 Fluid overload	0.010	0.990	0.000
E13 Other specified diabetes mellitus	0.010	0.990	0.000
E12 Malnutrition-related diabetes mellitus	0.010	0.990	0.000
E50-E64 Other nutritional deficiencies	0.010	0.990	0.000
E20-E35 Disorders of other endocrine glands	0.009	0.990	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.010	0.990	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.009	0.991	0.000
E40-E46 Malnutrition	0.009	0.991	0.000
E70-E90 Metabolic disorders	0.009	0.991	0.000
E11 Non-insulin-dependent diabetes mellitus	0.009	0.991	0.000
E61 Deficiency of other nutrient elements	0.009	0.991	0.000
I30-I52 Other forms of heart disease	0.009	0.991	0.000
E14.3 With ophthalmic complications	0.008	0.991	0.000
E14.9 Without complications	0.008	0.992	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.008	0.992	0.000
E55 Vitamin D deficiency	0.008	0.992	0.000
E87.6 Hypokalaemia	0.008	0.992	0.000
E61.1 Iron deficiency	0.008	0.992	0.000
E14.8 With unspecified complications	0.008	0.992	0.000
E14.7 With multiple complications	0.008	0.992	0.000
E14.6 With other specified complications	0.008	0.992	0.000
E14.5 With peripheral circulatory complications	0.008	0.992	0.000
E14.4 With neurological complications	0.008	0.992	0.000
E14.2 Withrenal complications	0.008	0.992	0.000
E14.1 With ketoacidosis	0.008	0.992	0.000
E14.0 With coma	0.008	0.992	0.000
E87.0 Hyperosmolality and hypernatraemia	0.008	0.992	0.000
E16 Other disorders of pancreatic internal secretion	0.008	0.992	0.000
E46 Unspecified protein-energy malnutrition	0.008	0.992	0.000
E22 Hyperfunction of pituitary gland	0.008	0.992	0.000
E65-E68 Obesity and other hyperalimentation	0.008	0.992	0.000
E87.2 Acidosis	0.008	0.992	0.000
E21.3 Hyperparathyroidism, unspecified	0.007	0.993	0.000
I42 Cardiomyopathy	0.007	0.993	0.000
E12.9 Without complications	0.007	0.993	0.000
E12.8 With unspecified complications	0.007	0.993	0.000
E12.7 With multiple complications	0.007	0.993	0.000
E12.6 With other specified complications	0.007	0.993	0.000
E12.5 With peripheral circulatory complications	0.007	0.993	0.000
E12.4 With neurological complications	0.007	0.993	0.000
E12.3 With ophthalmic complications	0.007	0.993	0.000
E12.2 With renal complications	0.007	0.993	0.000
E12.1 With ketoacidosis	0.007	0.993	0.000
E12.0 With coma	0.007	0.993	0.000
E13.9 Without complications	0.007	0.993	0.000
E13.8 With unspecified complications	0.007	0.993	0.000
E13.7 With multiple complications	0.007	0.993	0.000
E13.6 With other specified complications	0.007	0.993	0.000
E13.5 With peripheral circulatory complications	0.007	0.993	0.000
E13.4 With neurological complications	0.007	0.993	0.000
E13.3 With ophthalmic complications	0.007	0.993	0.000
E13.2 With renal complications	0.007	0.993	0.000
E13.1 With ketoacidosis	0.007	0.993	0.000
E13.0 With coma	0.007	0.993	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.007	0.993	0.000
E63 Other nutritional deficiencies	0.007	0.993	0.000
E56 Other vitamin deficiencies	0.007	0.993	0.000
E51 Thiamine deficiency	0.007	0.993	0.000
E50 Vitamin A deficiency	0.007	0.993	0.000
E60 Dietary zinc deficiency	0.007	0.993	0.000
E59 Dietary selenium deficiency	0.007	0.993	0.000
E58 Dietary calcium deficiency	0.007	0.993	0.000
E54 Ascorbic acid deficiency	0.007	0.993	0.000
E52 Niacin deficiency [pellagra]	0.007	0.993	0.000
E11.5 With peripheral circulatory complications	0.007	0.993	0.000
E28 Ovarian dysfunction	0.007	0.993	0.000
E55.9 Vitamin D deficiency, unspecified	0.007	0.993	0.000
E11.4 With neurological complications	0.007	0.993	0.000
E27 Other disorders of adrenal gland	0.007	0.993	0.000
I44 Atrioventricular and left bundle-branch block	0.007	0.993	0.000
E87.3 Alkalosis	0.007	0.993	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.007	0.993	0.000
E34 Other endocrine disorders	0.007	0.993	0.000
E32 Diseases of thymus	0.007	0.993	0.000
E31 Polyglandular dysfunction	0.007	0.993	0.000
E30 Disorders of puberty, not elsewhere classified	0.007	0.993	0.000
E29 Testicular dysfunction	0.007	0.993	0.000
E26 Hyperaldosteronism	0.007	0.993	0.000
E25 Adrenogenital disorders	0.007	0.993	0.000
E24 Cushing's syndrome	0.007	0.993	0.000
E20 Hypoparathyroidism	0.007	0.993	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.007	0.993	0.000
E87.4 Mixed disorder of acid-base balance	0.007	0.993	0.000
E11.6 With other specified complications	0.007	0.993	0.000
E11.3 With ophthalmic complications	0.007	0.993	0.000
E16.2 Hypoglycaemia, unspecified	0.007	0.993	0.000
E86 Volume depletion	0.007	0.993	0.000
I36 Nonrheumatic tricuspid valve disorders	0.007	0.993	0.000
E15 Nondiabetic hypoglycaemic coma	0.007	0.993	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.007	0.993	0.000
E45 Retarded development following protein-energy malnutrition	0.007	0.993	0.000
E43 Unspecified severe protein-energy malnutrition	0.007	0.993	0.000
E42 Marasmic kwashiorkor	0.007	0.993	0.000
E41 Nutritional marasmus	0.007	0.993	0.000
E40 Kwashiorkor	0.007	0.993	0.000
I30 Acute pericarditis	0.007	0.993	0.000
E85 Amyloidosis	0.007	0.993	0.000
E84 Cystic fibrosis	0.007	0.993	0.000
E79 Disorders of purine and pyrimidine metabolism	0.007	0.993	0.000
E77 Disorders of glycoprotein metabolism	0.007	0.993	0.000
E76 Disorders of glycosaminoglycan metabolism	0.007	0.993	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.007	0.993	0.000
E74 Other disorders of carbohydrate metabolism	0.007	0.993	0.000
E73 Lactose intolerance	0.007	0.993	0.000
E72 Other disorders of amino-acid metabolism	0.007	0.993	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.007	0.993	0.000
E70 Disorders of aromatic amino-acid metabolism	0.007	0.993	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.007	0.993	0.000
E83 Disorders of mineral metabolism	0.007	0.993	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.007	0.993	0.000
E11.8 With unspecified complications	0.006	0.993	0.000
E11.7 With multiple complications	0.006	0.993	0.000
E11.1 With ketoacidosis	0.006	0.993	0.000
E11.0 With coma	0.006	0.993	0.000
E61.9 Deficiency of nutrient element, unspecified	0.006	0.993	0.000
E61.8 Deficiency of other specified nutrient elements	0.006	0.993	0.000
E61.7 Deficiency of multiple nutrient elements	0.006	0.993	0.000
E61.6 Vanadium deficiency	0.006	0.993	0.000
E61.5 Molybdenum deficiency	0.006	0.993	0.000
E61.4 Chromium deficiency	0.006	0.993	0.000
E61.3 Manganese deficiency	0.006	0.993	0.000
E61.2 Magnesium deficiency	0.006	0.993	0.000
E61.0 Copper deficiency	0.006	0.993	0.000
E65 Localised adiposity	0.007	0.993	0.000
E00-E07 Disorders of thyroid gland	0.007	0.993	0.000
I52 Other heart disorders in diseases classified elsewhere	0.006	0.993	0.000
I48 Atrial fibrillation and flutter	0.006	0.993	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.006	0.993	0.000
I41 Myocarditis in diseases classified elsewhere	0.006	0.993	0.000
I40 Acute myocarditis	0.006	0.993	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.006	0.993	0.000
I37 Pulmonary valve disorders	0.006	0.993	0.000
I32 Pericarditis in diseases classified elsewhere	0.006	0.993	0.000
E23 Hypofunction and other disorders of pituitary gland	0.006	0.994	0.000
E53 Deficiency of other B group vitamins	0.006	0.994	0.000
I46 Cardiac arrest	0.006	0.994	0.000
E11.2 With renal complications	0.006	0.994	0.000
I49 Other cardiac arrhythmias	0.006	0.994	0.000
O63.1 Prolonged second stage (of labour)	0.006	0.994	0.000
E21.0 Primary hyperparathyroidism	0.006	0.994	0.000
E22.0 Acromegaly and pituitary gigantism	0.006	0.994	0.000
I42.9 Cardiomyopathy, unspecified	0.006	0.994	0.000
I44.7 Left bundle-branch block, unspecified	0.006	0.994	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.006	0.994	0.000
E21.4 Other specified disorders of parathyroid gland	0.006	0.994	0.000
E21.2 Other hyperparathyroidism	0.006	0.994	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.006	0.994	0.000
E55.0 Rickets, active	0.006	0.994	0.000
O63 Long labour	0.006	0.994	0.000
I44.6 Other and unspecified fascicular block	0.006	0.994	0.000
E83.1 Disorders of iron metabolism	0.006	0.994	0.000
I33 Acute and subacute endocarditis	0.006	0.994	0.000
I49.0 Ventricular fibrillation and flutter	0.006	0.994	0.000
E88 Other metabolic disorders	0.006	0.994	0.000
E27.1 Primary adrenocortical insufficiency	0.006	0.994	0.000
I44.3 Other and unspecified atrioventricular block	0.006	0.994	0.000
I47 Paroxysmal tachycardia	0.006	0.994	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.006	0.994	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.006	0.994	0.000
E16.4 Abnormal secretion of gastrin	0.006	0.994	0.000
E16.3 Increased secretion of glucagon	0.006	0.994	0.000
E16.1 Other hypoglycaemia	0.006	0.994	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.006	0.994	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.006	0.994	0.000
O60-O75 Complications of labour and delivery	0.006	0.994	0.000
I42.0 Dilated cardiomyopathy	0.006	0.994	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.006	0.994	0.000
E22.8 Other hyperfunction of pituitary gland	0.006	0.994	0.000
E22.1 Hyperprolactinaemia	0.006	0.994	0.000
E67 Other hyperalimentation	0.006	0.994	0.000
E68 Sequelae of hyperalimentation	0.006	0.994	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.006	0.994	0.000
E28.2 Polycystic ovarian syndrome	0.005	0.994	0.000
I44.1 Atrioventricular block, second degree	0.006	0.994	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.005	0.994	0.000
I42.8 Other cardiomyopathies	0.005	0.994	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.005	0.994	0.000
I42.6 Alcoholic cardiomyopathy	0.005	0.994	0.000
I42.5 Other restrictive cardiomyopathy	0.005	0.994	0.000
I42.4 Endocardial fibroelastosis	0.005	0.994	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.005	0.994	0.000
I42.2 Other hypertrophic cardiomyopathy	0.005	0.994	0.000
E50.9 Vitamin A deficiency, unspecified	0.005	0.994	0.000
E50.8 Other manifestations of vitamin A deficiency	0.005	0.994	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.005	0.994	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.005	0.994	0.000
E50.5 Vitamin A deficiency with night blindness	0.005	0.994	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.005	0.994	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.005	0.994	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.005	0.994	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.005	0.994	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.005	0.994	0.000
E51.9 Thiamine deficiency, unspecified	0.005	0.994	0.000
E51.8 Other manifestations of thiamine deficiency	0.005	0.994	0.000
E51.2 Wernicke's encephalopathy	0.005	0.994	0.000
E51.1 Beriberi	0.005	0.994	0.000
E56.9 Vitamin deficiency, unspecified	0.005	0.994	0.000
E56.8 Deficiency of other vitamins	0.005	0.994	0.000
E56.1 Deficiency of vitamin K	0.005	0.994	0.000
E56.0 Deficiency of vitamin E	0.005	0.994	0.000
E63.9 Nutritional deficiency, unspecified	0.005	0.994	0.000
E63.8 Other specified nutritional deficiencies	0.005	0.994	0.000
E63.1 Imbalance of constituents of food intake	0.005	0.994	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.005	0.994	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.005	0.994	0.000
E64.8 Sequelae of other nutritional deficiencies	0.005	0.994	0.000
E64.3 Sequelae of rickets	0.005	0.994	0.000
E64.2 Sequelae of vitamin C deficiency	0.005	0.994	0.000
E64.1 Sequelae of vitamin A deficiency	0.005	0.994	0.000
E64.0 Sequelae of protein-energy malnutrition	0.005	0.994	0.000
E28.9 Ovarian dysfunction, unspecified	0.005	0.994	0.000
E28.8 Other ovarian dysfunction	0.005	0.994	0.000
E28.3 Primary ovarian failure	0.005	0.994	0.000
E28.1 Androgen excess	0.005	0.994	0.000
E28.0 Oestrogen excess	0.005	0.994	0.000
E27.9 Disorder of adrenal gland, unspecified	0.005	0.995	0.000
E27.8 Other specified disorders of adrenal gland	0.005	0.995	0.000
E27.5 Adrenomedullary hyperfunction	0.005	0.995	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.005	0.995	0.000
E27.2 Addisonian crisis	0.005	0.995	0.000
E27.0 Other adrenocortical overactivity	0.005	0.995	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.005	0.995	0.000
I44.5 Left posterior fascicular block	0.005	0.995	0.000
I44.4 Left anterior fascicular block	0.005	0.995	0.000
I30.9 Acute pericarditis, unspecified	0.005	0.995	0.000
I38 Endocarditis, valve unspecified	0.005	0.995	0.000
E20.9 Hypoparathyroidism, unspecified	0.005	0.995	0.000
E20.8 Other hypoparathyroidism	0.005	0.995	0.000
E20.1 Pseudohypoparathyroidism	0.005	0.995	0.000
E20.0 Idiopathic hypoparathyroidism	0.005	0.995	0.000
E24.9 Cushing's syndrome, unspecified	0.005	0.995	0.000
E24.8 Other Cushing's syndrome	0.005	0.995	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.005	0.995	0.000
E24.3 Ectopic ACTH syndrome	0.005	0.995	0.000
E24.2 Drug-induced Cushing's syndrome	0.005	0.995	0.000
E24.1 Nelson's syndrome	0.005	0.995	0.000
E24.0 Pituitary-dependent Cushing's disease	0.005	0.995	0.000
E25.9 Adrenogenital disorder, unspecified	0.005	0.995	0.000
E25.8 Other adrenogenital disorders	0.005	0.995	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.005	0.995	0.000
E26.9 Hyperaldosteronism, unspecified	0.005	0.995	0.000
E26.8 Other hyperaldosteronism	0.005	0.995	0.000
E26.1 Secondary hyperaldosteronism	0.005	0.995	0.000
E26.0 Primary hyperaldosteronism	0.005	0.995	0.000
E29.9 Testicular dysfunction, unspecified	0.005	0.995	0.000
E29.8 Other testicular dysfunction	0.005	0.995	0.000
E29.1 Testicular hypofunction	0.005	0.995	0.000
E29.0 Testicular hyperfunction	0.005	0.995	0.000
E30.9 Disorder of puberty, unspecified	0.005	0.995	0.000
E30.8 Other disorders of puberty	0.005	0.995	0.000
E30.1 Precocious puberty	0.005	0.995	0.000
E30.0 Delayed puberty	0.005	0.995	0.000
E31.9 Polyglandular dysfunction, unspecified	0.005	0.995	0.000
E31.8 Other polyglandular dysfunction	0.005	0.995	0.000
E31.1 Polyglandular hyperfunction	0.005	0.995	0.000
E31.0 Autoimmune polyglandular failure	0.005	0.995	0.000
E32.9 Disease of thymus, unspecified	0.005	0.995	0.000
E32.8 Other diseases of thymus	0.005	0.995	0.000
E32.1 Abscess of thymus	0.005	0.995	0.000
E32.0 Persistent hyperplasia of thymus	0.005	0.995	0.000
E34.9 Endocrine disorder, unspecified	0.005	0.995	0.000
E34.8 Other specified endocrine disorders	0.005	0.995	0.000
E34.5 Androgen resistance syndrome	0.005	0.995	0.000
E34.4 Constitutional tall stature	0.005	0.995	0.000
E34.3 Short stature, not elsewhere classified	0.005	0.995	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.005	0.995	0.000
E34.1 Other hypersecretion of intestinal hormones	0.005	0.995	0.000
E34.0 Carcinoid syndrome	0.005	0.995	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.005	0.995	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.005	0.995	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.005	0.995	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.005	0.995	0.000
I49.4 Other and unspecified premature depolarisation	0.005	0.995	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.005	0.995	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.005	0.995	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.005	0.995	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.005	0.995	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.005	0.995	0.000
E44.1 Mild protein-energy malnutrition	0.005	0.995	0.000
E44.0 Moderate protein-energy malnutrition	0.005	0.995	0.000
I30.8 Other forms of acute pericarditis	0.005	0.995	0.000
I30.1 Infective pericarditis	0.005	0.995	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.005	0.995	0.000
I45 Other conduction disorders	0.005	0.995	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.005	0.995	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.005	0.995	0.000
E70.3 Albinism	0.005	0.995	0.000
E70.2 Disorders of tyrosine metabolism	0.005	0.995	0.000
E70.1 Other hyperphenylalaninaemias	0.005	0.995	0.000
E70.0 Classical phenylketonuria	0.005	0.995	0.000
E71.3 Disorders of fatty-acid metabolism	0.005	0.995	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.005	0.995	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.005	0.995	0.000
E71.0 Maple-syrup-urine disease	0.005	0.995	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.005	0.995	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.005	0.995	0.000
E72.5 Disorders of glycine metabolism	0.005	0.995	0.000
E72.4 Disorders of ornithine metabolism	0.005	0.995	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.005	0.995	0.000
E72.2 Disorders of urea cycle metabolism	0.005	0.995	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.005	0.995	0.000
E72.0 Disorders of amino-acid transport	0.005	0.995	0.000
E73.9 Lactose intolerance, unspecified	0.005	0.995	0.000
E73.8 Other lactose intolerance	0.005	0.995	0.000
E73.1 Secondary lactase deficiency	0.005	0.995	0.000
E73.0 Congenital lactase deficiency	0.005	0.995	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.005	0.995	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.005	0.995	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.005	0.995	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.005	0.995	0.000
E74.2 Disorders of galactose metabolism	0.005	0.995	0.000
E74.1 Disorders of fructose metabolism	0.005	0.995	0.000
E74.0 Glycogen storage disease	0.005	0.995	0.000
E75.6 Lipid storage disorder, unspecified	0.005	0.995	0.000
E75.5 Other lipid storage disorders	0.005	0.995	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.005	0.995	0.000
E75.3 Sphingolipidosis, unspecified	0.005	0.995	0.000
E75.2 Other sphingolipidosis	0.005	0.995	0.000
E75.1 Other gangliosidosis	0.005	0.995	0.000
E75.0 GM2 gangliosidosis	0.005	0.995	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.005	0.995	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.005	0.995	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.005	0.995	0.000
E76.2 Other mucopolysaccharidoses	0.005	0.995	0.000
E76.1 Mucopolysaccharidosis, type II	0.005	0.995	0.000
E76.0 Mucopolysaccharidosis, type I	0.005	0.995	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.005	0.995	0.000
E77.8 Other disorders of glycoprotein metabolism	0.005	0.995	0.000
E77.1 Defects in glycoprotein degradation	0.005	0.995	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.005	0.995	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.005	0.995	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.005	0.995	0.000
E79.1 Lesch-Nyhan syndrome	0.005	0.995	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.005	0.995	0.000
E84.9 Cystic fibrosis, unspecified	0.005	0.995	0.000
E84.8 Cystic fibrosis with other manifestations	0.005	0.995	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.005	0.995	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.005	0.995	0.000
E85.9 Amyloidosis, unspecified	0.005	0.995	0.000
E85.8 Other amyloidosis	0.005	0.995	0.000
E85.4 Organ-limited amyloidosis	0.005	0.995	0.000
E85.3 Secondary systemic amyloidosis	0.005	0.995	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.005	0.995	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.005	0.995	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.005	0.995	0.000
O63.9 Long labour, unspecified	0.005	0.995	0.000
O63.0 Prolonged first stage (of labour)	0.005	0.995	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.005	0.995	0.000
E83.8 Other disorders of mineral metabolism	0.005	0.995	0.000
E83.2 Disorders of zinc metabolism	0.005	0.995	0.000
E83.0 Disorders of copper metabolism	0.005	0.995	0.000
O66 Other obstructed labour	0.005	0.995	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.005	0.995	0.000
E80.6 Other disorders of bilirubin metabolism	0.005	0.995	0.000
E80.5 Crigler-Najjar syndrome	0.005	0.995	0.000
E80.3 Defects of catalase and peroxydase	0.005	0.995	0.000
E80.2 Other porphyria	0.005	0.995	0.000
E80.1 Porphyria cutanea tarda	0.005	0.995	0.000
E80.0 Hereditary erythropoietic porphyria	0.005	0.995	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.005	0.995	0.000
E05.9 Thyrotoxicosis, unspecified	0.005	0.995	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.005	0.995	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.005	0.995	0.000
E00 Congenital iodine-deficiency syndrome	0.005	0.995	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.005	0.995	0.000
E80.4 Gilbert's syndrome	0.005	0.995	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.005	0.995	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.005	0.995	0.000
I37.9 Pulmonary valve disorder, unspecified	0.005	0.995	0.000
I37.8 Other pulmonary valve disorders	0.005	0.995	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.005	0.995	0.000
I37.1 Pulmonary valve insufficiency	0.005	0.995	0.000
I37.0 Pulmonary valve stenosis	0.005	0.995	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.005	0.995	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.005	0.995	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.005	0.995	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.005	0.995	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.005	0.995	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.005	0.995	0.000
I40.9 Acute myocarditis, unspecified	0.005	0.995	0.000
I40.8 Other acute myocarditis	0.005	0.995	0.000
I40.1 Isolated myocarditis	0.005	0.995	0.000
I40.0 Infective myocarditis	0.005	0.995	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.005	0.995	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.005	0.995	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.005	0.995	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.005	0.995	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.005	0.995	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.005	0.995	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.005	0.995	0.000
I48.4 Atypical atrial flutter	0.005	0.995	0.000
I48.3 Typical atrial flutter	0.005	0.995	0.000
I48.2 Chronic atrial fibrillation	0.005	0.995	0.000
I48.1 Persistent atrial fibrillation	0.005	0.995	0.000
I48.0 Paroxysmal atrial fibrillation	0.005	0.995	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.005	0.995	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.005	0.995	0.000
I31 Other diseases of pericardium	0.005	0.995	0.000
O72 Postpartum haemorrhage	0.005	0.995	0.000
E23.7 Disorder of pituitary gland, unspecified	0.005	0.995	0.000
E23.6 Other disorders of pituitary gland	0.005	0.995	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.005	0.995	0.000
E23.2 Diabetes insipidus	0.005	0.995	0.000
E23.1 Drug-induced hypopituitarism	0.005	0.995	0.000
I44.2 Atrioventricular block, complete	0.005	0.995	0.000
I46.9 Cardiac arrest, unspecified	0.005	0.995	0.000
E53.9 Vitamin B deficiency, unspecified	0.005	0.995	0.000
E53.1 Pyridoxine deficiency	0.005	0.995	0.000
E53.0 Riboflavin deficiency	0.005	0.995	0.000
I46.1 Sudden cardiac death, so described	0.005	0.995	0.000
I73.9 Peripheral vascular disease, unspecified	0.000	0.995	0.005
O68 Labour and delivery complicated by foetal stress [distress]	0.005	0.995	0.000
I49.1 Atrial premature depolarisation	0.005	0.995	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.005	0.995	0.000
I49.2 Junctional premature depolarisation	0.005	0.995	0.000
I46.0 Cardiac arrest with successful resuscitation	0.005	0.995	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.005	0.995	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.005	0.995	0.000
E06 Thyroiditis	0.005	0.995	0.000
I33.9 Acute endocarditis, unspecified	0.004	0.995	0.000
I49.5 Sick sinus syndrome	0.005	0.995	0.000
E87.5 Hyperkalaemia	0.004	0.995	0.000
H25.1 Senile nuclear cataract	0.005	0.995	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.004	0.995	0.000
O61 Failed induction of labour	0.005	0.995	0.000
E83.3 Disorders of phosphorus metabolism	0.004	0.995	0.000
O64.1 Obstructed labour due to breech presentation	0.004	0.995	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.004	0.995	0.000
E88.9 Metabolic disorder, unspecified	0.004	0.995	0.000
E88.8 Other specified metabolic disorders	0.004	0.995	0.000
E88.3 Tumour lysis syndrome	0.004	0.995	0.000
E88.2 Lipomatosis, not elsewhere classified	0.004	0.995	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.004	0.995	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.004	0.995	0.000
I47.0 Reentry ventricular arrhythmia	0.004	0.995	0.000
I47.2 Ventricular tachycardia	0.004	0.995	0.000
E07 Other disorders of thyroid	0.004	0.995	0.000
E83.5 Disorders of calcium metabolism	0.004	0.996	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.004	0.996	0.000
E03 Other hypothyroidism	0.004	0.996	0.000
O74 Complications of anaesthesia during labour and delivery	0.004	0.996	0.000
O71 Other obstetric trauma	0.004	0.996	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.004	0.996	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.004	0.996	0.000
O62 Abnormalities of forces of labour	0.004	0.996	0.000
O60 Preterm delivery	0.004	0.996	0.000
E83.4 Disorders of magnesium metabolism	0.004	0.996	0.000
E67.8 Other specified hyperalimentation	0.004	0.996	0.000
E67.3 Hypervitaminosis D	0.004	0.996	0.000
E67.2 Megavitamin-B6 syndrome	0.004	0.996	0.000
E67.1 Hypercarotenaemia	0.004	0.996	0.000
E67.0 Hypervitaminosis A	0.004	0.996	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.004	0.996	0.000
E05.8 Other thyrotoxicosis	0.004	0.996	0.000
E05.5 Thyroid crisis or storm	0.004	0.996	0.000
E05.4 Thyrotoxicosis factitia	0.004	0.996	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.004	0.996	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.004	0.996	0.000
I33.0 Acute and subacute infective endocarditis	0.004	0.996	0.000
E23.0 Hypopituitarism	0.004	0.996	0.000
O73 Retained placenta and membranes, without haemorrhage	0.004	0.996	0.000
I49.3 Ventricular premature depolarisation	0.004	0.996	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.004	0.996	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.004	0.996	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.004	0.996	0.000
I49.8 Other specified cardiac arrhythmias	0.004	0.996	0.000
I45.5 Other specified heart block	0.004	0.996	0.000
O72.0 Third-stage haemorrhage	0.004	0.996	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.004	0.996	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.004	0.996	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.004	0.996	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.004	0.996	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.004	0.996	0.000
E89.5 Postprocedural testicular hypofunction	0.004	0.996	0.000
E89.4 Postprocedural ovarian failure	0.004	0.996	0.000
E89.3 Postprocedural hypopituitarism	0.004	0.996	0.000
E89.2 Postprocedural hypoparathyroidism	0.004	0.996	0.000
E89.1 Postprocedural hypoinsulinaemia	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations