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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs422951
log Bayes Factor = 141.828
Chromosome 6   position 32,188,383  (GRCh37) Explore rs422951 on Ensembl!
Variant rs422951 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E11.9 Without complications
1.000 0.000 0.000
G35 Multiple sclerosis
0.000 0.000 1.000
E20-E35 Disorders of other endocrine glands
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.999 0.001 0.000
E10.3 With ophthalmic complications
0.997 0.003 0.000
E03 Other hypothyroidism
0.997 0.003 0.000
E03.9 Hypothyroidism, unspecified
0.995 0.005 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.986 0.014 0.000
E10.1 With ketoacidosis
0.985 0.015 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.984 0.016 0.000
E27 Other disorders of adrenal gland
0.981 0.019 0.000
E21.3 Hyperparathyroidism, unspecified
0.978 0.022 0.000
E16 Other disorders of pancreatic internal secretion
0.973 0.027 0.000
E16.2 Hypoglycaemia, unspecified
0.958 0.042 0.000
E11.3 With ophthalmic complications
0.954 0.046 0.000
E13 Other specified diabetes mellitus
0.954 0.046 0.000
E14 Unspecified diabetes mellitus
0.950 0.050 0.000
E11.2 With renal complications
0.950 0.050 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.061 0.939
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.067 0.933
E13.9 Without complications
0.929 0.071 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.072 0.928
M06 Other rheumatoid arthritis
0.000 0.087 0.913
E24 Cushing's syndrome
0.911 0.089 0.000
E11.1 With ketoacidosis
0.902 0.098 0.000
E10.2 With renal complications
0.898 0.102 0.000
E27.1 Primary adrenocortical insufficiency
0.896 0.104 0.000
E14.3 With ophthalmic complications
0.894 0.106 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.892 0.108 0.000
E23 Hypofunction and other disorders of pituitary gland
0.881 0.119 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.874 0.126 0.000
N00-N08 Glomerular diseases
0.871 0.129 0.000
N05 Unspecified nephritic syndrome
0.867 0.133 0.000
N04 Nephrotic syndrome
0.866 0.134 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.859 0.141 0.000
K90 Intestinal malabsorption
0.857 0.143 0.000
M06.0 Seronegative rheumatoid arthritis
0.000 0.149 0.851
M06.3 Rheumatoid nodule
0.000 0.151 0.849
N04.9 Unspecified
0.849 0.151 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.844 0.156 0.000
L40.0 Psoriasis vulgaris
0.835 0.165 0.000
L40.1 Generalised pustular psoriasis
0.834 0.166 0.000
E14.8 With unspecified complications
0.833 0.167 0.000
K90.9 Intestinal malabsorption, unspecified
0.826 0.174 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.824 0.176 0.000
L40.4 Guttate psoriasis
0.823 0.177 0.000
E24.2 Drug-induced Cushing's syndrome
0.817 0.183 0.000
N05.2 Diffuse membranous glomerulonephritis
0.815 0.185 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.190 0.810
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.192 0.808
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.198 0.802
E10.0 With coma
0.801 0.199 0.000
E28 Ovarian dysfunction
0.800 0.200 0.000
M06.34 Rheumatoid nodule (Hand)
0.000 0.209 0.791
E14.5 With peripheral circulatory complications
0.788 0.212 0.000
E11.7 With multiple complications
0.787 0.213 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.785 0.215 0.000
E10.5 With peripheral circulatory complications
0.779 0.221 0.000
E23.7 Disorder of pituitary gland, unspecified
0.779 0.221 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.777 0.223 0.000
E10.7 With multiple complications
0.771 0.228 0.000
G37 Other demyelinating diseases of central nervous system
0.000 0.230 0.770
N05.9 Unspecified
0.770 0.230 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.231 0.769
E10.6 With other specified complications
0.766 0.234 0.000
E20 Hypoparathyroidism
0.765 0.235 0.000
E23.6 Other disorders of pituitary gland
0.765 0.235 0.000
E24.0 Pituitary-dependent Cushing's disease
0.762 0.238 0.000
E31 Polyglandular dysfunction
0.757 0.243 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.757 0.243 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.248 0.752
N04.2 Diffuse membranous glomerulonephritis
0.751 0.249 0.000
E07 Other disorders of thyroid
0.748 0.251 0.000
E27.9 Disorder of adrenal gland, unspecified
0.747 0.253 0.000
E10.4 With neurological complications
0.737 0.263 0.000
N05.1 Focal and segmental glomerular lesions
0.736 0.264 0.000
E21.4 Other specified disorders of parathyroid gland
0.728 0.272 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.272 0.728
E11.6 With other specified complications
0.726 0.274 0.000
L40.3 Pustulosis palmaris et plantaris
0.721 0.278 0.000
E16.1 Other hypoglycaemia
0.718 0.282 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.718 0.282 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.717 0.283 0.000
E32 Diseases of thymus
0.717 0.283 0.000
E30 Disorders of puberty, not elsewhere classified
0.717 0.283 0.000
E03.5 Myxoedema coma
0.715 0.285 0.000
E03.4 Atrophy of thyroid (acquired)
0.715 0.285 0.000
E03.3 Postinfectious hypothyroidism
0.715 0.285 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.715 0.285 0.000
E23.2 Diabetes insipidus
0.709 0.291 0.000
E21.2 Other hyperparathyroidism
0.707 0.292 0.000
E15 Nondiabetic hypoglycaemic coma
0.706 0.294 0.000
E29 Testicular dysfunction
0.705 0.295 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.297 0.703
E27.5 Adrenomedullary hyperfunction
0.703 0.297 0.000
E27.0 Other adrenocortical overactivity
0.703 0.297 0.000
E10.8 With unspecified complications
0.702 0.298 0.000
E14.1 With ketoacidosis
0.700 0.300 0.000
N03 Chronic nephritic syndrome
0.699 0.301 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.698 0.302 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.698 0.302 0.000
E16.4 Abnormal secretion of gastrin
0.698 0.302 0.000
E16.3 Increased secretion of glucagon
0.698 0.302 0.000
N04.1 Focal and segmental glomerular lesions
0.696 0.304 0.000
L40.8 Other psoriasis
0.695 0.304 0.000
E14.4 With neurological complications
0.691 0.309 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.691 0.309 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.313 0.687
E03.1 Congenital hypothyroidism without goitre
0.687 0.313 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.315 0.685
E13.8 With unspecified complications
0.684 0.316 0.000
E13.7 With multiple complications
0.684 0.316 0.000
E13.6 With other specified complications
0.684 0.316 0.000
E13.5 With peripheral circulatory complications
0.684 0.316 0.000
E13.4 With neurological complications
0.684 0.316 0.000
E13.2 With renal complications
0.684 0.316 0.000
E13.1 With ketoacidosis
0.684 0.316 0.000
E13.0 With coma
0.684 0.316 0.000
N04.8 Other
0.682 0.318 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.681 0.319 0.000
E14.7 With multiple complications
0.681 0.319 0.000
E14.0 With coma
0.681 0.319 0.000
E03.8 Other specified hypothyroidism
0.678 0.322 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.677 0.322 0.000
E65-E68 Obesity and other hyperalimentation
0.675 0.325 0.000
E27.2 Addisonian crisis
0.674 0.326 0.000
E14.6 With other specified complications
0.672 0.328 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.332 0.668
E11.5 With peripheral circulatory complications
0.668 0.332 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.333 0.667
E14.2 Withrenal complications
0.666 0.334 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.663 0.337 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.340 0.660
E11.0 With coma
0.657 0.343 0.000
M06.4 Inflammatory polyarthropathy
0.000 0.343 0.657
M06.8 Other specified rheumatoid arthritis
0.000 0.346 0.654
M06.2 Rheumatoid bursitis
0.000 0.346 0.654
M06.1 Adult-onset Still's disease
0.000 0.346 0.654
E24.8 Other Cushing's syndrome
0.653 0.346 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.653 0.346 0.000
E24.3 Ectopic ACTH syndrome
0.653 0.346 0.000
E24.1 Nelson's syndrome
0.653 0.346 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.648 0.352 0.000
N05.8 Other
0.644 0.356 0.000
K90.8 Other intestinal malabsorption
0.643 0.357 0.000
E26 Hyperaldosteronism
0.640 0.360 0.000
E05.8 Other thyrotoxicosis
0.639 0.361 0.000
E07.8 Other specified disorders of thyroid
0.634 0.366 0.000
N02 Recurrent and persistent haematuria
0.633 0.367 0.000
E28.3 Primary ovarian failure
0.632 0.368 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.631 0.368 0.000
E23.1 Drug-induced hypopituitarism
0.631 0.368 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.369 0.631
E40-E46 Malnutrition
0.630 0.369 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.374 0.626
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.625 0.375 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.624 0.375 0.000
N06 Isolated proteinuria with specified morphological lesion
0.624 0.375 0.000
N01 Rapidly progressive nephritic syndrome
0.624 0.375 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.377 0.623
N05.6 Dense deposit disease
0.621 0.378 0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.621 0.378 0.000
N05.0 Minor glomerular abnormality
0.621 0.378 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.621 0.379 0.000
N04.6 Dense deposit disease
0.621 0.379 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.621 0.379 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.621 0.379 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.621 0.379 0.000
N04.0 Minor glomerular abnormality
0.621 0.379 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.380 0.620
N03.1 Focal and segmental glomerular lesions
0.617 0.383 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.616 0.384 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.616 0.384 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.616 0.384 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.616 0.384 0.000
K90.3 Pancreatic steatorrhoea
0.614 0.385 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.614 0.385 0.000
K90.1 Tropical sprue
0.614 0.385 0.000
E24.9 Cushing's syndrome, unspecified
0.613 0.387 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.390 0.610
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.390 0.610
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.390 0.610
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.391 0.609
M06.38 Rheumatoid nodule (Other)
0.000 0.391 0.609
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.391 0.609
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.391 0.609
M06.33 Rheumatoid nodule (Forearm)
0.000 0.391 0.609
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.391 0.609
E28.2 Polycystic ovarian syndrome
0.608 0.392 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.394 0.605
N02.2 Diffuse membranous glomerulonephritis
0.604 0.396 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.398 0.601
E27.8 Other specified disorders of adrenal gland
0.599 0.401 0.000
E13.3 With ophthalmic complications
0.598 0.402 0.000
M05-M14 Inflammatory polyarthropathies
0.021 0.403 0.575
E20.9 Hypoparathyroidism, unspecified
0.596 0.404 0.000
E25 Adrenogenital disorders
0.593 0.406 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.001 0.409 0.590
M05 Seropositive rheumatoid arthritis
0.009 0.410 0.581
N00 Acute nephritic syndrome
0.587 0.413 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.414 0.586
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.584 0.416 0.000
E31.0 Autoimmune polyglandular failure
0.583 0.417 0.000
N05.7 Diffuse crescentic glomerulonephritis
0.582 0.418 0.000
G36 Other acute disseminated demyelination
0.000 0.420 0.579
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.422 0.577
E28.9 Ovarian dysfunction, unspecified
0.574 0.426 0.000
E28.8 Other ovarian dysfunction
0.574 0.426 0.000
E28.1 Androgen excess
0.574 0.426 0.000
E28.0 Oestrogen excess
0.574 0.426 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.433 0.567
E06 Thyroiditis
0.565 0.435 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.436 0.564
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.438 0.562
E11.8 With unspecified complications
0.561 0.439 0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis
0.557 0.443 0.000
N03.8 Other
0.556 0.444 0.000
G37.5 Concentric sclerosis [Balo]
0.000 0.448 0.552
G37.4 Subacute necrotising myelitis
0.000 0.448 0.552
G37.2 Central pontine myelinolysis
0.000 0.448 0.552
G37.1 Central demyelination of corpus callosum
0.000 0.448 0.552
G37.0 Diffuse sclerosis
0.000 0.448 0.552
E20.8 Other hypoparathyroidism
0.548 0.452 0.000
E20.1 Pseudohypoparathyroidism
0.548 0.452 0.000
E20.0 Idiopathic hypoparathyroidism
0.548 0.452 0.000
E31.9 Polyglandular dysfunction, unspecified
0.543 0.457 0.000
E31.8 Other polyglandular dysfunction
0.543 0.457 0.000
E31.1 Polyglandular hyperfunction
0.543 0.457 0.000
E22 Hyperfunction of pituitary gland
0.542 0.458 0.000
E34 Other endocrine disorders
0.542 0.458 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.461 0.539
E07.1 Dyshormogenetic goitre
0.537 0.463 0.000
E07.0 Hypersecretion of calcitonin
0.537 0.463 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.467 0.533
E83.1 Disorders of iron metabolism
0.000 0.471 0.529
L40-L45 Papulosquamous disorders
0.517 0.483 0.000
E65 Localised adiposity
0.514 0.486 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E30.9 Disorder of puberty, unspecified
0.514 0.486 0.000
E30.8 Other disorders of puberty
0.514 0.486 0.000
E30.1 Precocious puberty
0.514 0.486 0.000
E30.0 Delayed puberty
0.514 0.486 0.000
E32.9 Disease of thymus, unspecified
0.514 0.486 0.000
E32.8 Other diseases of thymus
0.514 0.486 0.000
E32.1 Abscess of thymus
0.514 0.486 0.000
E32.0 Persistent hyperplasia of thymus
0.514 0.486 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.514 0.486 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.514 0.486 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.514 0.486 0.000
E29.9 Testicular dysfunction, unspecified
0.506 0.494 0.000
E29.8 Other testicular dysfunction
0.506 0.494 0.000
E29.0 Testicular hyperfunction
0.506 0.494 0.000
N02.3 Diffuse mesangial proliferative glomerulonephritis
0.503 0.497 0.000
N03.7 Diffuse crescentic glomerulonephritis
0.501 0.499 0.000
N03.6 Dense deposit disease
0.501 0.499 0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis
0.501 0.499 0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis
0.501 0.499 0.000
N03.2 Diffuse membranous glomerulonephritis
0.501 0.499 0.000
N03.0 Minor glomerular abnormality
0.501 0.499 0.000
E21.0 Primary hyperparathyroidism
0.497 0.503 0.000
E29.1 Testicular hypofunction
0.494 0.506 0.000
E50-E64 Other nutritional deficiencies
0.489 0.511 0.000
E67 Other hyperalimentation
0.484 0.516 0.000
E68 Sequelae of hyperalimentation
0.484 0.516 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.529 0.471
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.529 0.471
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.529 0.471
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.529 0.471
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.529 0.471
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.529 0.471
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.529 0.471
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.531 0.469
M06.18 Adult-onset Still's disease (Other)
0.000 0.531 0.469
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.531 0.469
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.531 0.469
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.531 0.469
M06.14 Adult-onset Still's disease (Hand)
0.000 0.531 0.469
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.531 0.469
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.531 0.469
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.531 0.469
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.531 0.469
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.531 0.469
M06.28 Rheumatoid bursitis (Other)
0.000 0.531 0.469
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.531 0.469
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.531 0.469
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.531 0.469
M06.24 Rheumatoid bursitis (Hand)
0.000 0.531 0.469
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.531 0.469
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.531 0.469
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.531 0.469
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.531 0.469
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.531 0.469
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.531 0.469
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.531 0.469
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.531 0.469
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.531 0.469
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.531 0.469
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.531 0.469
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.531 0.469
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.531 0.469
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.531 0.469
E22.1 Hyperprolactinaemia
0.463 0.537 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.538 0.461
E26.8 Other hyperaldosteronism
0.459 0.541 0.000
E26.1 Secondary hyperaldosteronism
0.459 0.541 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.001 0.542 0.457
N02.7 Diffuse crescentic glomerulonephritis
0.454 0.546 0.000
N02.6 Dense deposit disease
0.454 0.546 0.000
N02.5 Diffuse mesangiocapillary glomerulonephritis
0.454 0.546 0.000
N02.4 Diffuse endocapillary proliferative glomerulonephritis
0.454 0.546 0.000
N02.1 Focal and segmental glomerular lesions
0.454 0.546 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.452 0.548 0.000
E45 Retarded development following protein-energy malnutrition
0.452 0.548 0.000
E43 Unspecified severe protein-energy malnutrition
0.452 0.548 0.000
E42 Marasmic kwashiorkor
0.452 0.548 0.000
E41 Nutritional marasmus
0.452 0.548 0.000
E40 Kwashiorkor
0.452 0.548 0.000
N01.9 Unspecified
0.448 0.552 0.000
N01.8 Other
0.448 0.552 0.000
N01.7 Diffuse crescentic glomerulonephritis
0.448 0.552 0.000
N01.6 Dense deposit disease
0.448 0.552 0.000
N01.5 Diffuse mesangiocapillary glomerulonephritis
0.448 0.552 0.000
N01.4 Diffuse endocapillary proliferative glomerulonephritis
0.448 0.552 0.000
N01.3 Diffuse mesangial proliferative glomerulonephritis
0.448 0.552 0.000
N01.2 Diffuse membranous glomerulonephritis
0.448 0.552 0.000
N01.1 Focal and segmental glomerular lesions
0.448 0.552 0.000
N01.0 Minor glomerular abnormality
0.448 0.552 0.000
N06.9 Unspecified
0.448 0.552 0.000
N06.8 Other
0.448 0.552 0.000
N06.7 Diffuse crescentic glomerulonephritis
0.448 0.552 0.000
N06.6 Dense deposit disease
0.448 0.552 0.000
N06.5 Diffuse mesangiocapillary glomerulonephritis
0.448 0.552 0.000
N06.4 Diffuse endocapillary proliferative glomerulonephritis
0.448 0.552 0.000
N06.3 Diffuse mesangial proliferative glomerulonephritis
0.448 0.552 0.000
N06.2 Diffuse membranous glomerulonephritis
0.448 0.552 0.000
N06.1 Focal and segmental glomerular lesions
0.448 0.552 0.000
N06.0 Minor glomerular abnormality
0.448 0.552 0.000
N07.9 Unspecified
0.448 0.552 0.000
N07.8 Other
0.448 0.552 0.000
N07.7 Diffuse crescentic glomerulonephritis
0.448 0.552 0.000
N07.6 Dense deposit disease
0.448 0.552 0.000
N07.5 Diffuse mesangiocapillary glomerulonephritis
0.448 0.552 0.000
N07.4 Diffuse endocapillary proliferative glomerulonephritis
0.448 0.552 0.000
N07.3 Diffuse mesangial proliferative glomerulonephritis
0.448 0.552 0.000
N07.2 Diffuse membranous glomerulonephritis
0.448 0.552 0.000
N07.1 Focal and segmental glomerular lesions
0.448 0.552 0.000
N07.0 Minor glomerular abnormality
0.448 0.552 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.001 0.563 0.437
L43 Lichen planus
0.437 0.563 0.000
E26.0 Primary hyperaldosteronism
0.429 0.571 0.000
M05.1 Rheumatoid lung disease
0.006 0.571 0.423
M09 Juvenile arthritis in diseases classified elsewhere
0.015 0.572 0.413
E25.9 Adrenogenital disorder, unspecified
0.425 0.574 0.000
E25.8 Other adrenogenital disorders
0.425 0.574 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.001 0.576 0.423
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.001 0.576 0.423
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.001 0.576 0.423
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.006 0.577 0.417
M05.0 Felty's syndrome
0.006 0.577 0.417
M08 Juvenile arthritis
0.015 0.577 0.407
N00.8 Other
0.421 0.579 0.000
N00.7 Diffuse crescentic glomerulonephritis
0.421 0.579 0.000
N00.6 Dense deposit disease
0.421 0.579 0.000
N00.5 Diffuse mesangiocapillary glomerulonephritis
0.421 0.579 0.000
N00.4 Diffuse endocapillary proliferative glomerulonephritis
0.421 0.579 0.000
N00.3 Diffuse mesangial proliferative glomerulonephritis
0.421 0.579 0.000
N00.2 Diffuse membranous glomerulonephritis
0.421 0.579 0.000
N00.1 Focal and segmental glomerular lesions
0.421 0.579 0.000
N00.0 Minor glomerular abnormality
0.421 0.579 0.000
M05.8 Other seropositive rheumatoid arthritis
0.006 0.580 0.414
E26.9 Hyperaldosteronism, unspecified
0.419 0.581 0.000
M12 Other specific arthropathies
0.014 0.581 0.405
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.001 0.581 0.418
E06.9 Thyroiditis, unspecified
0.418 0.582 0.000
G36.9 Acute disseminated demyelination, unspecified
0.000 0.584 0.415
G36.8 Other specified acute disseminated demyelination
0.000 0.584 0.415
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.584 0.415
G36.0 Neuromyelitis optica [Devic]
0.000 0.584 0.415
M05.2 Rheumatoid vasculitis
0.006 0.584 0.409
E07.9 Disorder of thyroid, unspecified
0.415 0.585 0.000
E34.8 Other specified endocrine disorders
0.415 0.585 0.000
N02.0 Minor glomerular abnormality
0.415 0.585 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.001 0.588 0.411
E06.4 Drug-induced thyroiditis
0.405 0.595 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.405 0.595 0.000
E06.0 Acute thyroiditis
0.405 0.595 0.000
L44 Other papulosquamous disorders
0.400 0.600 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.001 0.602 0.398
M07 Psoriatic and enteropathic arthropathies
0.153 0.603 0.245
E66 Obesity
0.397 0.603 0.000
E06.5 Other chronic thyroiditis
0.390 0.609 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.389 0.611 0.000
E22.8 Other hyperfunction of pituitary gland
0.389 0.611 0.000
E34.5 Androgen resistance syndrome
0.388 0.611 0.000
E34.4 Constitutional tall stature
0.388 0.611 0.000
E34.3 Short stature, not elsewhere classified
0.388 0.611 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.388 0.611 0.000
E34.1 Other hypersecretion of intestinal hormones
0.388 0.611 0.000
E06.1 Subacute thyroiditis
0.386 0.614 0.000
N00.9 Unspecified
0.383 0.616 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.619 0.381
E51 Thiamine deficiency
0.375 0.625 0.000
L43.9 Lichen planus, unspecified
0.373 0.627 0.000
L41 Parapsoriasis
0.370 0.629 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.370 0.629 0.000
E46 Unspecified protein-energy malnutrition
0.365 0.634 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.351 0.649 0.000
E63 Other nutritional deficiencies
0.351 0.649 0.000
E50 Vitamin A deficiency
0.351 0.649 0.000
E60 Dietary zinc deficiency
0.351 0.649 0.000
E59 Dietary selenium deficiency
0.351 0.649 0.000
E54 Ascorbic acid deficiency
0.351 0.649 0.000
E52 Niacin deficiency [pellagra]
0.351 0.649 0.000
E34.0 Carcinoid syndrome
0.347 0.652 0.000
E67.8 Other specified hyperalimentation
0.347 0.653 0.000
E67.3 Hypervitaminosis D
0.347 0.653 0.000
E67.2 Megavitamin-B6 syndrome
0.347 0.653 0.000
E67.1 Hypercarotenaemia
0.347 0.653 0.000
E67.0 Hypervitaminosis A
0.347 0.653 0.000
M07.3 Other psoriatic arthropathies
0.336 0.657 0.008
E56 Other vitamin deficiencies
0.342 0.658 0.000
E58 Dietary calcium deficiency
0.340 0.660 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.339 0.661 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.334 0.666 0.000
E53 Deficiency of other B group vitamins
0.334 0.666 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.330 0.669 0.001
M14 Arthropathies in other diseases classified elsewhere
0.016 0.669 0.314
E11.4 With neurological complications
0.329 0.671 0.000
E66.8 Other obesity
0.325 0.675 0.000
E44.1 Mild protein-energy malnutrition
0.324 0.676 0.000
E44.0 Moderate protein-energy malnutrition
0.324 0.676 0.000
L43.8 Other lichen planus
0.319 0.680 0.000
L43.0 Hypertrophic lichen planus
0.319 0.681 0.000
L44.0 Pityriasis rubra pilaris
0.316 0.684 0.000
M12.3 Palindromic rheumatism
0.009 0.685 0.306
M05.19 Rheumatoid lung disease (Site unspecified)
0.004 0.686 0.310
L43.3 Subacute (active) lichen planus
0.313 0.687 0.000
L43.2 Lichenoid drug reaction
0.313 0.687 0.000
L43.1 Bullous lichen planus
0.313 0.687 0.000
M05.18 Rheumatoid lung disease (Other)
0.005 0.692 0.303
M05.17 Rheumatoid lung disease (Ankle and foot)
0.005 0.692 0.303
M05.16 Rheumatoid lung disease (Lower leg)
0.005 0.692 0.303
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.005 0.692 0.303
M05.14 Rheumatoid lung disease (Hand)
0.005 0.692 0.303
M05.13 Rheumatoid lung disease (Forearm)
0.005 0.692 0.303
M05.12 Rheumatoid lung disease (Upper arm)
0.005 0.692 0.303
M05.11 Rheumatoid lung disease (Shoulder region)
0.005 0.692 0.303
M05.10 Rheumatoid lung disease (Multiple sites)
0.005 0.692 0.303
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.011 0.693 0.296
M09.2 Juvenile arthritis in ulcerative colitis
0.011 0.693 0.296
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.011 0.693 0.296
M09.0 Juvenile arthritis in psoriasis
0.011 0.693 0.296
M05.09 Felty's syndrome (Site unspecified)
0.005 0.697 0.299
M05.08 Felty's syndrome (Other)
0.005 0.697 0.299
M05.07 Felty's syndrome (Ankle and foot)
0.005 0.697 0.299
M05.06 Felty's syndrome (Lower leg)
0.005 0.697 0.299
M05.05 Felty's syndrome (Pelvic region and thigh)
0.005 0.697 0.299
M05.04 Felty's syndrome (Hand)
0.005 0.697 0.299
M05.03 Felty's syndrome (Forearm)
0.005 0.697 0.299
M05.02 Felty's syndrome (Upper arm)
0.005 0.697 0.299
M05.01 Felty's syndrome (Shoulder region)
0.005 0.697 0.299
M05.00 Felty's syndrome (Multiple sites)
0.005 0.697 0.299
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.005 0.697 0.299
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.005 0.697 0.299

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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