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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4248149
log Bayes Factor = 64.4551
Chromosome 6   position 30,767,627  (GRCh37) Explore rs4248149 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.002 0.998
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.006 0.994
E50-E64 Other nutritional deficiencies
0.000 0.010 0.990
E53 Deficiency of other B group vitamins
0.000 0.018 0.982
E10.3 With ophthalmic complications
0.000 0.023 0.977
E53.8 Deficiency of other specified B group vitamins
0.000 0.023 0.977
L40.0 Psoriasis vulgaris
0.973 0.027 0.000
E10.4 With neurological complications
0.000 0.028 0.972
E10.5 With peripheral circulatory complications
0.000 0.065 0.935
L40.1 Generalised pustular psoriasis
0.874 0.126 0.000
E10.2 With renal complications
0.000 0.184 0.816
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.187 0.813
E10.8 With unspecified complications
0.000 0.191 0.809
E06 Thyroiditis
0.000 0.195 0.805
E10.6 With other specified complications
0.000 0.207 0.792
E55 Vitamin D deficiency
0.000 0.213 0.787
T36-T50 Poisoning by drugs, medicaments and biological substances
0.769 0.231 0.000
E10.0 With coma
0.000 0.236 0.764
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.762 0.238 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.751 0.249 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.749 0.251 0.000
E10.1 With ketoacidosis
0.000 0.251 0.749
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.740 0.260 0.000
L40.8 Other psoriasis
0.738 0.262 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.732 0.268 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.731 0.269 0.000
E04 Other non-toxic goitre
0.000 0.282 0.718
E10.7 With multiple complications
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E05.8 Other thyrotoxicosis
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
T43.2 Other and unspecified antidepressants
0.717 0.283 0.000
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.290 0.709
E63 Other nutritional deficiencies
0.000 0.290 0.709
E56 Other vitamin deficiencies
0.000 0.290 0.709
E51 Thiamine deficiency
0.000 0.290 0.709
E50 Vitamin A deficiency
0.000 0.290 0.709
E60 Dietary zinc deficiency
0.000 0.290 0.709
E59 Dietary selenium deficiency
0.000 0.290 0.709
E58 Dietary calcium deficiency
0.000 0.290 0.709
E54 Ascorbic acid deficiency
0.000 0.290 0.709
E52 Niacin deficiency [pellagra]
0.000 0.290 0.709
E53.9 Vitamin B deficiency, unspecified
0.000 0.296 0.704
E53.1 Pyridoxine deficiency
0.000 0.296 0.704
E53.0 Riboflavin deficiency
0.000 0.296 0.704
E06.3 Autoimmune thyroiditis
0.000 0.302 0.698
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.308 0.692
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.692 0.308 0.000
E07 Other disorders of thyroid
0.000 0.311 0.689
T43.3 Phenothiazine antipsychotics and neuroleptics
0.682 0.318 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.320 0.680
E04.9 Non-toxic goitre, unspecified
0.000 0.327 0.673
T43.0 Tricyclic and tetracyclic antidepressants
0.668 0.332 0.000
E61 Deficiency of other nutrient elements
0.000 0.333 0.667
E13 Other specified diabetes mellitus
0.000 0.338 0.662
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.648 0.352 0.000
E55.9 Vitamin D deficiency, unspecified
0.000 0.358 0.642
E03.1 Congenital hypothyroidism without goitre
0.000 0.361 0.639
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.630 0.370 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.619 0.381 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.608 0.391 0.000
E03.8 Other specified hypothyroidism
0.000 0.392 0.608
T42.4 Benzodiazepines
0.608 0.392 0.000
E40-E46 Malnutrition
0.000 0.407 0.592
E15 Nondiabetic hypoglycaemic coma
0.000 0.417 0.583
T43.6 Psychostimulants with abuse potential
0.579 0.421 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.579 0.421 0.000
E06.5 Other chronic thyroiditis
0.000 0.423 0.577
E06.4 Drug-induced thyroiditis
0.000 0.423 0.577
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.423 0.577
E06.1 Subacute thyroiditis
0.000 0.423 0.577
E06.0 Acute thyroiditis
0.000 0.423 0.577
E16.2 Hypoglycaemia, unspecified
0.000 0.428 0.572
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.569 0.430 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.568 0.432 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.433 0.567
E55.0 Rickets, active
0.000 0.435 0.564
T36 Poisoning by systemic antibiotics
0.557 0.443 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.553 0.447 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.551 0.449 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.551 0.449 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.551 0.449 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.551 0.449 0.000
M07.3 Other psoriatic arthropathies
0.549 0.451 0.000
T43.9 Psychotropic drug, unspecified
0.547 0.453 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.547 0.453 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.547 0.453 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.544 0.456 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.543 0.457 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.541 0.459 0.000
T50.8 Diagnostic agents
0.538 0.461 0.000
T50.7 Analeptics and opioid receptor antagonists
0.538 0.461 0.000
T50.5 Appetite depressants
0.538 0.461 0.000
T50.4 Drugs affecting uric acid metabolism
0.538 0.461 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.538 0.461 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.538 0.461 0.000
T50.1 Loop [high-ceiling] diuretics
0.538 0.461 0.000
T50.0 Mineralocorticoids and their antagonists
0.538 0.461 0.000
K90 Intestinal malabsorption
0.000 0.463 0.537
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.537 0.463 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.537 0.463 0.000
T42.3 Barbiturates
0.537 0.463 0.000
T42.2 Succinimides and oxazolidinediones
0.537 0.463 0.000
T42.0 Hydantoin derivatives
0.537 0.463 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.530 0.470 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.530 0.470 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.530 0.470 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.530 0.470 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.530 0.470 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.530 0.470 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.530 0.470 0.000
T44.0 Anticholinesterase agents
0.530 0.470 0.000
T47.0 Histamine H(2)-receptor antagonists
0.527 0.472 0.000
T39.1 4-Aminophenol derivatives
0.525 0.475 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.482 0.518
E04.8 Other specified non-toxic goitre
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.486 0.513
E12.9 Without complications
0.000 0.487 0.513
E12.8 With unspecified complications
0.000 0.487 0.513
E12.7 With multiple complications
0.000 0.487 0.513
E12.6 With other specified complications
0.000 0.487 0.513
E12.5 With peripheral circulatory complications
0.000 0.487 0.513
E12.4 With neurological complications
0.000 0.487 0.513
E12.3 With ophthalmic complications
0.000 0.487 0.513
E12.2 With renal complications
0.000 0.487 0.513
E12.1 With ketoacidosis
0.000 0.487 0.513
E12.0 With coma
0.000 0.487 0.513
E06.9 Thyroiditis, unspecified
0.000 0.490 0.510
E50.9 Vitamin A deficiency, unspecified
0.000 0.491 0.509
E50.8 Other manifestations of vitamin A deficiency
0.000 0.491 0.509
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.491 0.509
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.491 0.509
E50.5 Vitamin A deficiency with night blindness
0.000 0.491 0.509
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.491 0.509
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.491 0.509
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.491 0.509
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.491 0.509
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.491 0.509
E51.9 Thiamine deficiency, unspecified
0.000 0.491 0.509
E51.8 Other manifestations of thiamine deficiency
0.000 0.491 0.509
E51.2 Wernicke's encephalopathy
0.000 0.491 0.509
E51.1 Beriberi
0.000 0.491 0.509
E56.9 Vitamin deficiency, unspecified
0.000 0.491 0.509
E56.8 Deficiency of other vitamins
0.000 0.491 0.509
E56.1 Deficiency of vitamin K
0.000 0.491 0.509
E56.0 Deficiency of vitamin E
0.000 0.491 0.509
E63.9 Nutritional deficiency, unspecified
0.000 0.491 0.509
E63.8 Other specified nutritional deficiencies
0.000 0.491 0.509
E63.1 Imbalance of constituents of food intake
0.000 0.491 0.509
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.491 0.509
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.491 0.509
E64.8 Sequelae of other nutritional deficiencies
0.000 0.491 0.509
E64.3 Sequelae of rickets
0.000 0.491 0.509
E64.2 Sequelae of vitamin C deficiency
0.000 0.491 0.509
E64.1 Sequelae of vitamin A deficiency
0.000 0.491 0.509
E64.0 Sequelae of protein-energy malnutrition
0.000 0.491 0.509
T43.5 Other and unspecified antipsychotics and neuroleptics
0.502 0.498 0.000
E07.1 Dyshormogenetic goitre
0.000 0.506 0.494
E07.0 Hypersecretion of calcitonin
0.000 0.506 0.494
E65-E68 Obesity and other hyperalimentation
0.000 0.508 0.492
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.512 0.487
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.512 0.487
E16.4 Abnormal secretion of gastrin
0.000 0.512 0.487
E16.3 Increased secretion of glucagon
0.000 0.512 0.487
E16.1 Other hypoglycaemia
0.000 0.516 0.484
T42.1 Iminostilbenes
0.481 0.519 0.000
E61.9 Deficiency of nutrient element, unspecified
0.000 0.522 0.478
E61.8 Deficiency of other specified nutrient elements
0.000 0.522 0.478
E61.7 Deficiency of multiple nutrient elements
0.000 0.522 0.478
E61.6 Vanadium deficiency
0.000 0.522 0.478
E61.5 Molybdenum deficiency
0.000 0.522 0.478
E61.4 Chromium deficiency
0.000 0.522 0.478
E61.3 Manganese deficiency
0.000 0.522 0.478
E61.2 Magnesium deficiency
0.000 0.522 0.478
E61.0 Copper deficiency
0.000 0.522 0.478
E13.8 With unspecified complications
0.000 0.525 0.474
E13.7 With multiple complications
0.000 0.525 0.474
E13.6 With other specified complications
0.000 0.525 0.474
E13.5 With peripheral circulatory complications
0.000 0.525 0.474
E13.4 With neurological complications
0.000 0.525 0.474
E13.3 With ophthalmic complications
0.000 0.525 0.474
E13.2 With renal complications
0.000 0.525 0.474
E13.1 With ketoacidosis
0.000 0.525 0.474
E13.0 With coma
0.000 0.525 0.474
K90.9 Intestinal malabsorption, unspecified
0.000 0.535 0.465
T46.4 Angiotensin-converting-enzyme inhibitors
0.464 0.535 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.461 0.539 0.000
E04.0 Non-toxic diffuse goitre
0.000 0.542 0.458
T47.1 Other antacids and anti-gastric-secretion drugs
0.457 0.543 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.452 0.548 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.452 0.548 0.000
T47.7 Emetics
0.452 0.548 0.000
T47.6 Antidiarrhoeal drugs
0.452 0.548 0.000
T47.5 Digestants
0.452 0.548 0.000
T47.4 Other laxatives
0.452 0.548 0.000
T47.3 Saline and osmotic laxatives
0.452 0.548 0.000
T47.2 Stimulant laxatives
0.452 0.548 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.450 0.550 0.000
T45.0 Antiallergic and antiemetic drugs
0.447 0.553 0.000
E04.1 Non-toxic single thyroid nodule
0.000 0.559 0.441
E61.1 Iron deficiency
0.000 0.564 0.436
T39.0 Salicylates
0.435 0.565 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.434 0.566 0.000
T38.1 Thyroid hormones and substitutes
0.431 0.569 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.575 0.425
E45 Retarded development following protein-energy malnutrition
0.000 0.575 0.425
E43 Unspecified severe protein-energy malnutrition
0.000 0.575 0.425
E42 Marasmic kwashiorkor
0.000 0.575 0.425
E41 Nutritional marasmus
0.000 0.575 0.425
E40 Kwashiorkor
0.000 0.575 0.425
E14 Unspecified diabetes mellitus
0.000 0.578 0.422
E13.9 Without complications
0.000 0.579 0.421
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.415 0.585 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.415 0.585 0.000
T46.7 Peripheral vasodilators
0.415 0.585 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.415 0.585 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.415 0.585 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.415 0.585 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.415 0.585 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.415 0.585 0.000
T38.9 Other and unspecified hormone antagonists
0.408 0.592 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.408 0.592 0.000
T38.7 Androgens and anabolic congeners
0.408 0.592 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.408 0.592 0.000
T38.5 Other oestrogens and progestogens
0.408 0.592 0.000
T38.4 Oral contraceptives
0.408 0.592 0.000
T38.2 Antithyroid drugs
0.408 0.592 0.000
T38.0 Glucocorticoids and synthetic analogues
0.408 0.592 0.000
T39.4 Antirheumatics, not elsewhere classified
0.407 0.592 0.000
T39.2 Pyrazolone derivatives
0.407 0.592 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.407 0.593 0.000
T36.0 Penicillins
0.405 0.594 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.404 0.596 0.000
T36.9 Systemic antibiotic, unspecified
0.399 0.600 0.000
T36.8 Other systemic antibiotics
0.399 0.600 0.000
T36.7 Antifungal antibiotics, systemically used
0.399 0.600 0.000
T36.6 Rifamycins
0.399 0.600 0.000
T36.5 Aminoglycosides
0.399 0.600 0.000
T36.4 Tetracyclines
0.399 0.600 0.000
T36.3 Macrolides
0.399 0.600 0.000
T36.2 Chloramphenicol group
0.399 0.600 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.399 0.600 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.395 0.605 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.395 0.605 0.000
T37.5 Antiviral drugs
0.395 0.605 0.000
T37.4 Anthelminthics
0.395 0.605 0.000
T37.3 Other antiprotozoal drugs
0.395 0.605 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.395 0.605 0.000
T37.1 Antimycobacterial drugs
0.395 0.605 0.000
T37.0 Sulphonamides
0.395 0.605 0.000
T41.5 Therapeutic gases
0.395 0.605 0.000
T41.4 Anaesthetic, unspecified
0.395 0.605 0.000
T41.3 Local anaesthetics
0.395 0.605 0.000
T41.2 Other and unspecified general anaesthetics
0.395 0.605 0.000
T41.1 Intravenous anaesthetics
0.395 0.605 0.000
T41.0 Inhaled anaesthetics
0.395 0.605 0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.395 0.605 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.395 0.605 0.000
T48.5 Anti-common-cold drugs
0.395 0.605 0.000
T48.4 Expectorants
0.395 0.605 0.000
T48.3 Antitussives
0.395 0.605 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.395 0.605 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.395 0.605 0.000
T48.0 Oxytocic drugs
0.395 0.605 0.000
T49.9 Topical agent, unspecified
0.395 0.605 0.000
T49.8 Other topical agents
0.395 0.605 0.000
T49.7 Dental drugs, topically applied
0.395 0.605 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.395 0.605 0.000
T49.5 Ophthalmological drugs and preparations
0.395 0.605 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.395 0.605 0.000
T49.3 Emollients, demulcents and protectants
0.395 0.605 0.000
T49.2 Local astringents and local detergents
0.395 0.605 0.000
T49.1 Antipruritics
0.395 0.605 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.395 0.605 0.000
M07.38 Other psoriatic arthropathies (Other)
0.394 0.606 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.394 0.606 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.394 0.606 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.394 0.606 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.394 0.606 0.000
T46.1 Calcium-channel blockers
0.393 0.606 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.388 0.612 0.000
T45.8 Other primarily systemic and haematological agents
0.388 0.612 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.388 0.612 0.000
T45.6 Fibrinolysis-affecting drugs
0.388 0.612 0.000
T45.4 Iron and its compounds
0.388 0.612 0.000
T45.3 Enzymes, not elsewhere classified
0.388 0.612 0.000
T45.2 Vitamins, not elsewhere classified
0.388 0.612 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.615 0.385
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.615 0.385
K90.1 Tropical sprue
0.000 0.615 0.385
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.636 0.364
T45.1 Antineoplastic and immunosuppressive drugs
0.364 0.636 0.000
N20.0 Calculus of kidney
0.359 0.641 0.000
K90.8 Other intestinal malabsorption
0.000 0.647 0.353
E67 Other hyperalimentation
0.000 0.647 0.352
E68 Sequelae of hyperalimentation
0.000 0.647 0.352
N20 Calculus of kidney and ureter
0.344 0.656 0.000
N20.1 Calculus of ureter
0.334 0.666 0.000
E07.8 Other specified disorders of thyroid
0.001 0.668 0.331
E14.3 With ophthalmic complications
0.000 0.676 0.324
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.320 0.679 0.000
T45.5 Anticoagulants
0.310 0.690 0.000
N20-N23 Urolithiasis
0.305 0.695 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.695 0.305
E44.0 Moderate protein-energy malnutrition
0.000 0.695 0.305
E14.8 With unspecified complications
0.000 0.697 0.303
E14.7 With multiple complications
0.000 0.697 0.303
E14.6 With other specified complications
0.000 0.697 0.303
E14.2 Withrenal complications
0.000 0.697 0.303
E14.0 With coma
0.000 0.697 0.303
N23 Unspecified renal colic
0.302 0.698 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.698 0.301
E14.4 With neurological complications
0.000 0.709 0.291
E20-E35 Disorders of other endocrine glands
0.000 0.710 0.289
E14.5 With peripheral circulatory complications
0.000 0.727 0.273
E14.1 With ketoacidosis
0.000 0.729 0.271
E65 Localised adiposity
0.000 0.730 0.270
E66 Obesity
0.000 0.737 0.263
E67.8 Other specified hyperalimentation
0.000 0.747 0.253
E67.3 Hypervitaminosis D
0.000 0.747 0.253
E67.2 Megavitamin-B6 syndrome
0.000 0.747 0.253
E67.1 Hypercarotenaemia
0.000 0.747 0.253
E67.0 Hypervitaminosis A
0.000 0.747 0.253
E27 Other disorders of adrenal gland
0.000 0.747 0.252
N20.9 Urinary calculus, unspecified
0.240 0.760 0.000
M07 Psoriatic and enteropathic arthropathies
0.239 0.760 0.001
E27.1 Primary adrenocortical insufficiency
0.000 0.761 0.239
E66.8 Other obesity
0.000 0.773 0.227
L40-L45 Papulosquamous disorders
0.223 0.777 0.001
N22 Calculus of urinary tract in diseases classified elsewhere
0.219 0.781 0.000
E24 Cushing's syndrome
0.000 0.790 0.210
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.209 0.790 0.001
E34 Other endocrine disorders
0.000 0.790 0.209
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.792 0.208
E32 Diseases of thymus
0.000 0.792 0.208
E31 Polyglandular dysfunction
0.000 0.792 0.208
E30 Disorders of puberty, not elsewhere classified
0.000 0.792 0.208
E25 Adrenogenital disorders
0.000 0.792 0.208
E04.2 Non-toxic multinodular goitre
0.000 0.797 0.203
E29 Testicular dysfunction
0.000 0.802 0.198
E27.8 Other specified disorders of adrenal gland
0.000 0.805 0.195
E22 Hyperfunction of pituitary gland
0.000 0.805 0.195
E27.2 Addisonian crisis
0.000 0.805 0.195
E28 Ovarian dysfunction
0.000 0.808 0.192
E66.1 Drug-induced obesity
0.000 0.811 0.189
E20 Hypoparathyroidism
0.000 0.813 0.186
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.815 0.185
E27.5 Adrenomedullary hyperfunction
0.000 0.819 0.181
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.819 0.181
E27.0 Other adrenocortical overactivity
0.000 0.819 0.181
N21 Calculus of lower urinary tract
0.173 0.827 0.000
M07.6 Other enteropathic arthropathies
0.171 0.828 0.001
M07.5 Arthropathy in ulcerative colitis
0.171 0.828 0.001
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.171 0.828 0.001
M07.2 Psoriatic spondylitis
0.171 0.828 0.001
M07.1 Arthritis mutilans
0.171 0.828 0.001
M07.0 Distal interphalangeal psoriatic arthropathy
0.171 0.828 0.001
E70-E90 Metabolic disorders
0.000 0.832 0.167
E34.8 Other specified endocrine disorders
0.000 0.833 0.167
E66.0 Obesity due to excess calories
0.000 0.834 0.166
E26 Hyperaldosteronism
0.000 0.835 0.165
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.838 0.162
E28.3 Primary ovarian failure
0.000 0.838 0.161
L44 Other papulosquamous disorders
0.160 0.840 0.001
L41 Parapsoriasis
0.160 0.840 0.001
L45 Papulosquamous disorders in diseases classified elsewhere
0.160 0.840 0.001
E24.9 Cushing's syndrome, unspecified
0.000 0.840 0.160
E89.0 Postprocedural hypothyroidism
0.000 0.840 0.160
N22.8 Calculus of urinary tract in other diseases classified elsewhere
0.157 0.843 0.000
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]
0.157 0.843 0.000
E22.1 Hyperprolactinaemia
0.000 0.845 0.155
E24.8 Other Cushing's syndrome
0.000 0.849 0.151
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.849 0.151
E24.3 Ectopic ACTH syndrome
0.000 0.849 0.151
E24.1 Nelson's syndrome
0.000 0.849 0.151
E24.0 Pituitary-dependent Cushing's disease
0.000 0.849 0.151
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.150 0.849 0.001
T40.8 Lysergide [LSD]
0.150 0.849 0.001
T40.7 Cannabis (derivatives)
0.150 0.849 0.001
T40.5 Cocaine
0.150 0.849 0.001
T40.3 Methadone
0.150 0.849 0.001
T40.1 Heroin
0.150 0.849 0.001
T40.0 Opium
0.150 0.849 0.001
E34.5 Androgen resistance syndrome
0.000 0.850 0.150
E34.4 Constitutional tall stature
0.000 0.850 0.150
E34.3 Short stature, not elsewhere classified
0.000 0.850 0.150
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.850 0.150
E34.1 Other hypersecretion of intestinal hormones
0.000 0.850 0.150
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.850 0.150
E25.9 Adrenogenital disorder, unspecified
0.000 0.851 0.149
E25.8 Other adrenogenital disorders
0.000 0.851 0.149
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.851 0.149
E30.9 Disorder of puberty, unspecified
0.000 0.851 0.149
E30.8 Other disorders of puberty
0.000 0.851 0.149
E30.1 Precocious puberty
0.000 0.851 0.149
E30.0 Delayed puberty
0.000 0.851 0.149
E31.9 Polyglandular dysfunction, unspecified
0.000 0.851 0.149
E31.8 Other polyglandular dysfunction
0.000 0.851 0.149
E31.1 Polyglandular hyperfunction
0.000 0.851 0.149
E31.0 Autoimmune polyglandular failure
0.000 0.851 0.149
E32.9 Disease of thymus, unspecified
0.000 0.851 0.149
E32.8 Other diseases of thymus
0.000 0.851 0.149
E32.1 Abscess of thymus
0.000 0.851 0.149
E32.0 Persistent hyperplasia of thymus
0.000 0.851 0.149
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.851 0.149
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.851 0.149
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.851 0.149
E34.0 Carcinoid syndrome
0.000 0.856 0.144
E24.2 Drug-induced Cushing's syndrome
0.000 0.857 0.143
E29.9 Testicular dysfunction, unspecified
0.000 0.858 0.142
E29.8 Other testicular dysfunction
0.000 0.858 0.142
E29.0 Testicular hyperfunction
0.000 0.858 0.142
L42 Pityriasis rosea
0.141 0.858 0.001
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.860 0.140
E22.8 Other hyperfunction of pituitary gland
0.000 0.860 0.140
E73 Lactose intolerance
0.000 0.861 0.139
T40.6 Other and unspecified narcotics
0.138 0.861 0.001
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.862 0.138
E28.9 Ovarian dysfunction, unspecified
0.000 0.862 0.138
E28.8 Other ovarian dysfunction
0.000 0.862 0.138
E28.1 Androgen excess
0.000 0.862 0.138
E28.0 Oestrogen excess
0.000 0.862 0.138
E34.9 Endocrine disorder, unspecified
0.000 0.862 0.138
E20.8 Other hypoparathyroidism
0.000 0.866 0.134
E20.1 Pseudohypoparathyroidism
0.000 0.866 0.134
E20.0 Idiopathic hypoparathyroidism
0.000 0.866 0.134
J45.9 Asthma, unspecified
0.000 0.866 0.134
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.132 0.867 0.001
E74 Other disorders of carbohydrate metabolism
0.000 0.867 0.133
E14.9 Without complications
0.000 0.867 0.133
E29.1 Testicular hypofunction
0.000 0.868 0.132
E89.2 Postprocedural hypoparathyroidism
0.000 0.869 0.131
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.871 0.129
J45 Asthma
0.000 0.875 0.125
N21.9 Calculus of lower urinary tract, unspecified
0.124 0.875 0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.123 0.876 0.001
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.123 0.876 0.001
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.123 0.876 0.001
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.123 0.876 0.001
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.123 0.876 0.001
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.123 0.876 0.001
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.123 0.876 0.001
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.123 0.876 0.001
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.123 0.876 0.001
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.123 0.876 0.001
M07.19 Arthritis mutilans (Site unspecified)
0.123 0.876 0.001
M07.18 Arthritis mutilans (Other)
0.123 0.876 0.001
M07.17 Arthritis mutilans (Ankle and foot)
0.123 0.876 0.001
M07.16 Arthritis mutilans (Lower leg)
0.123 0.876 0.001
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.123 0.876 0.001
M07.14 Arthritis mutilans (Hand)
0.123 0.876 0.001
M07.13 Arthritis mutilans (Forearm)
0.123 0.876 0.001
M07.12 Arthritis mutilans (Upper arm)
0.123 0.876 0.001
M07.11 Arthritis mutilans (Shoulder region)
0.123 0.876 0.001
M07.10 Arthritis mutilans (Multiple sites)
0.123 0.876 0.001
M07.29 Psoriatic spondylitis (Site unspecified)
0.123 0.876 0.001
M07.28 Psoriatic spondylitis (Other)
0.123 0.876 0.001
M07.27 Psoriatic spondylitis (Ankle and foot)
0.123 0.876 0.001
M07.26 Psoriatic spondylitis (Lower leg)
0.123 0.876 0.001
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.123 0.876 0.001
M07.24 Psoriatic spondylitis (Hand)
0.123 0.876 0.001
M07.23 Psoriatic spondylitis (Forearm)
0.123 0.876 0.001
M07.22 Psoriatic spondylitis (Upper arm)
0.123 0.876 0.001
M07.21 Psoriatic spondylitis (Shoulder region)
0.123 0.876 0.001
M07.20 Psoriatic spondylitis (Multiple sites)
0.123 0.876 0.001
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.123 0.876 0.001
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.123 0.876 0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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