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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4253418
log Bayes Factor = 6.71583
Chromosome 4   position 187,199,497  (GRCh37) Explore rs4253418 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.000 1.000
I26 Pulmonary embolism
0.000 0.046 0.954
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.066 0.934
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.080 0.920
I80 Phlebitis and thrombophlebitis
0.000 0.085 0.915
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.141 0.859
Chapter IX Diseases of the circulatory system
0.000 0.147 0.853
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.159 0.841
I27 Other pulmonary heart diseases
0.000 0.172 0.828
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.235 0.765
I27.0 Primary pulmonary hypertension
0.000 0.255 0.745
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.268 0.732
I30-I52 Other forms of heart disease
0.000 0.270 0.730
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.316 0.684
I05-I09 Chronic rheumatic heart diseases
0.000 0.336 0.664
I28 Other diseases of pulmonary vessels
0.000 0.340 0.660
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.342 0.658
I42 Cardiomyopathy
0.000 0.346 0.654
I47 Paroxysmal tachycardia
0.000 0.352 0.648
I86 Varicose veins of other sites
0.000 0.356 0.644
I85 Oesophageal varices
0.000 0.361 0.639
I87 Other disorders of veins
0.000 0.366 0.634
I27.9 Pulmonary heart disease, unspecified
0.000 0.371 0.629
I47.2 Ventricular tachycardia
0.000 0.377 0.623
I00-I02 Acute rheumatic fever
0.000 0.388 0.612
I27.2 Other secondary pulmonary hypertension
0.000 0.393 0.607
I81 Portal vein thrombosis
0.000 0.396 0.604
I07 Rheumatic tricuspid valve diseases
0.000 0.396 0.604
I27.8 Other specified pulmonary heart diseases
0.000 0.406 0.594
I27.1 Kyphoscoliotic heart disease
0.000 0.406 0.594
I30 Acute pericarditis
0.000 0.413 0.587
I44 Atrioventricular and left bundle-branch block
0.000 0.416 0.584
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.417 0.583
I31 Other diseases of pericardium
0.000 0.432 0.568
I89.0 Lymphoedema, not elsewhere classified
0.000 0.432 0.567
I33 Acute and subacute endocarditis
0.000 0.433 0.567
I36 Nonrheumatic tricuspid valve disorders
0.000 0.435 0.565
I07.1 Tricuspid insufficiency
0.000 0.440 0.560
I88 Nonspecific lymphadenitis
0.000 0.442 0.558
I86.4 Gastric varices
0.000 0.444 0.556
I82 Other venous embolism and thrombosis
0.000 0.447 0.553
I38 Endocarditis, valve unspecified
0.000 0.448 0.552
I42.9 Cardiomyopathy, unspecified
0.000 0.453 0.547
I60-I69 Cerebrovascular diseases
0.000 0.469 0.531
I44.2 Atrioventricular block, complete
0.000 0.472 0.528
I42.0 Dilated cardiomyopathy
0.000 0.474 0.526
I37 Pulmonary valve disorders
0.000 0.476 0.524
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.476 0.524
I42.2 Other hypertrophic cardiomyopathy
0.000 0.477 0.523
I52 Other heart disorders in diseases classified elsewhere
0.000 0.477 0.523
I48 Atrial fibrillation and flutter
0.000 0.477 0.523
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.477 0.523
I41 Myocarditis in diseases classified elsewhere
0.000 0.477 0.523
I40 Acute myocarditis
0.000 0.477 0.523
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.477 0.523
I32 Pericarditis in diseases classified elsewhere
0.000 0.477 0.523
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.489 0.511
I46 Cardiac arrest
0.000 0.496 0.504
I45 Other conduction disorders
0.000 0.502 0.498
I85.0 Oesophageal varices with bleeding
0.000 0.504 0.496
I49 Other cardiac arrhythmias
0.000 0.513 0.487
I30.9 Acute pericarditis, unspecified
0.000 0.515 0.485
I63 Cerebral infarction
0.000 0.515 0.485
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.516 0.483
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.517 0.482
I09 Other rheumatic heart diseases
0.000 0.523 0.476
I06 Rheumatic aortic valve diseases
0.000 0.523 0.476
I42.8 Other cardiomyopathies
0.000 0.524 0.476
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.527 0.473
I28.8 Other specified diseases of pulmonary vessels
0.000 0.527 0.473
I28.1 Aneurysm of pulmonary artery
0.000 0.527 0.473
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.527 0.473
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.528 0.472
I89.1 Lymphangitis
0.000 0.530 0.470
I31.3 Pericardial effusion (noninflammatory)
0.000 0.530 0.470
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.531 0.469
I42.6 Alcoholic cardiomyopathy
0.000 0.531 0.469
I42.5 Other restrictive cardiomyopathy
0.000 0.531 0.469
I42.4 Endocardial fibroelastosis
0.000 0.531 0.469
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.531 0.469
I86.8 Varicose veins of other specified sites
0.000 0.538 0.462
I86.3 Vulval varices
0.000 0.538 0.462
I86.2 Pelvic varices
0.000 0.538 0.462
I86.0 Sublingual varices
0.000 0.538 0.462
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.541 0.459
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.544 0.456
I87.9 Disorder of vein, unspecified
0.000 0.545 0.455
I87.0 Postphlebitic syndrome
0.000 0.545 0.455
I33.0 Acute and subacute infective endocarditis
0.000 0.549 0.451
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.552 0.447
I34 Nonrheumatic mitral valve disorders
0.000 0.557 0.443
I85.9 Oesophageal varices without bleeding
0.000 0.560 0.440
I02 Rheumatic chorea
0.000 0.561 0.439
I01 Rheumatic fever with heart involvement
0.000 0.561 0.439
I00 Rheumatic fever without mention of heart involvement
0.000 0.561 0.439
I82.8 Embolism and thrombosis of other specified veins
0.000 0.562 0.438
I44.3 Other and unspecified atrioventricular block
0.000 0.563 0.437
I87.1 Compression of vein
0.000 0.563 0.436
I07.9 Tricuspid valve disease, unspecified
0.000 0.567 0.433
I07.8 Other tricuspid valve diseases
0.000 0.567 0.433
I07.2 Tricuspid stenosis with insufficiency
0.000 0.567 0.433
I07.0 Tricuspid stenosis
0.000 0.567 0.433
I47.0 Reentry ventricular arrhythmia
0.000 0.573 0.427
I83 Varicose veins of lower extremities
0.000 0.573 0.426
I44.0 Atrioventricular block, first degree
0.000 0.575 0.425
I30.8 Other forms of acute pericarditis
0.000 0.579 0.421
I30.1 Infective pericarditis
0.000 0.579 0.421
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.579 0.421
I44.5 Left posterior fascicular block
0.000 0.581 0.419
I44.4 Left anterior fascicular block
0.000 0.581 0.419
I45.6 Preexcitation syndrome
0.000 0.582 0.418
I69 Sequelae of cerebrovascular disease
0.000 0.582 0.418
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.585 0.415
I63.8 Other cerebral infarction
0.000 0.587 0.413
I49.9 Cardiac arrhythmia, unspecified
0.000 0.591 0.409
I31.8 Other specified diseases of pericardium
0.000 0.592 0.407
I31.2 Haemopericardium, not elsewhere classified
0.000 0.592 0.407
I31.1 Chronic constrictive pericarditis
0.000 0.592 0.407
I31.0 Chronic adhesive pericarditis
0.000 0.592 0.407
I33.9 Acute endocarditis, unspecified
0.000 0.593 0.407
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.595 0.405
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.595 0.405
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.595 0.405
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.595 0.405
I88.8 Other nonspecific lymphadenitis
0.000 0.600 0.400
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.600 0.400
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.600 0.400
I49.5 Sick sinus syndrome
0.000 0.600 0.400
I05 Rheumatic mitral valve diseases
0.000 0.600 0.399
I87.8 Other specified disorders of veins
0.000 0.603 0.397
I82.3 Embolism and thrombosis of renal vein
0.000 0.604 0.396
I82.1 Thrombophlebitis migrans
0.000 0.604 0.396
I82.0 Budd-Chiari syndrome
0.000 0.604 0.396
I49.8 Other specified cardiac arrhythmias
0.000 0.609 0.391
I44.7 Left bundle-branch block, unspecified
0.000 0.610 0.390
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.613 0.387
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.614 0.386
I45.9 Conduction disorder, unspecified
0.000 0.614 0.386
I51 Complications and ill-defined descriptions of heart disease
0.000 0.618 0.382
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.619 0.381
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.619 0.381
I31.9 Disease of pericardium, unspecified
0.000 0.621 0.379
I37.1 Pulmonary valve insufficiency
0.000 0.624 0.376
I37.9 Pulmonary valve disorder, unspecified
0.000 0.624 0.375
I37.8 Other pulmonary valve disorders
0.000 0.624 0.375
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.624 0.375
I37.0 Pulmonary valve stenosis
0.000 0.624 0.375
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.625 0.375
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.625 0.375
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.625 0.375
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.625 0.375
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.625 0.375
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.625 0.375
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.625 0.375
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.625 0.375
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.625 0.375
I40.9 Acute myocarditis, unspecified
0.000 0.625 0.375
I40.8 Other acute myocarditis
0.000 0.625 0.375
I40.1 Isolated myocarditis
0.000 0.625 0.375
I40.0 Infective myocarditis
0.000 0.625 0.375
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.625 0.375
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.625 0.375
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.625 0.375
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.625 0.375
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.625 0.375
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.625 0.375
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.625 0.375
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.625 0.375
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.625 0.375
I48.4 Atypical atrial flutter
0.000 0.625 0.375
I48.3 Typical atrial flutter
0.000 0.625 0.375
I48.2 Chronic atrial fibrillation
0.000 0.625 0.375
I48.1 Persistent atrial fibrillation
0.000 0.625 0.375
I48.0 Paroxysmal atrial fibrillation
0.000 0.625 0.375
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.625 0.375
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.625 0.375
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.625 0.375
I44.1 Atrioventricular block, second degree
0.000 0.626 0.374
I46.0 Cardiac arrest with successful resuscitation
0.000 0.629 0.370
I95 Hypotension
0.000 0.631 0.369
I08 Multiple valve diseases
0.000 0.632 0.368
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.635 0.365
I46.1 Sudden cardiac death, so described
0.000 0.638 0.361
I45.3 Trifascicular block
0.000 0.642 0.358
I45.8 Other specified conduction disorders
0.000 0.643 0.357
I45.4 Nonspecific intraventricular block
0.000 0.643 0.357
I45.0 Right fascicular block
0.000 0.643 0.357
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.647 0.353
I61 Intracerebral haemorrhage
0.000 0.648 0.352
I49.2 Junctional premature depolarisation
0.000 0.651 0.349
I44.6 Other and unspecified fascicular block
0.000 0.652 0.348
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.652 0.348
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.652 0.348
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.652 0.348
I51.9 Heart disease, unspecified
0.000 0.654 0.345
I99 Other and unspecified disorders of circulatory system
0.000 0.655 0.345
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.656 0.344
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.657 0.343
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.658 0.342
I69.3 Sequelae of cerebral infarction
0.000 0.658 0.342
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.658 0.342
I06.8 Other rheumatic aortic valve diseases
0.000 0.658 0.342
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.658 0.342
I06.1 Rheumatic aortic insufficiency
0.000 0.658 0.342
I06.0 Rheumatic aortic stenosis
0.000 0.658 0.342
I09.9 Rheumatic heart disease, unspecified
0.000 0.658 0.342
I09.8 Other specified rheumatic heart diseases
0.000 0.658 0.342
I09.2 Chronic rheumatic pericarditis
0.000 0.658 0.342
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.658 0.342
I09.0 Rheumatic myocarditis
0.000 0.658 0.342
I45.2 Bifascicular block
0.000 0.660 0.340
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.665 0.335
I45.5 Other specified heart block
0.000 0.667 0.333
I46.9 Cardiac arrest, unspecified
0.000 0.668 0.332
I50 Heart failure
0.000 0.670 0.330
I63.9 Cerebral infarction, unspecified
0.000 0.671 0.329
I82.2 Embolism and thrombosis of vena cava
0.000 0.671 0.328
I62 Other nontraumatic intracranial haemorrhage
0.000 0.673 0.327
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.673 0.327
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.673 0.327
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.673 0.327
I86.1 Scrotal varices
0.000 0.673 0.326
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.677 0.322
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.682 0.317
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.682 0.317
I74 Arterial embolism and thrombosis
0.000 0.683 0.317
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.685 0.315
I01.8 Other acute rheumatic heart disease
0.000 0.685 0.315
I01.2 Acute rheumatic myocarditis
0.000 0.685 0.315
I01.1 Acute rheumatic endocarditis
0.000 0.685 0.315
I01.0 Acute rheumatic pericarditis
0.000 0.685 0.315
I02.9 Rheumatic chorea without heart involvement
0.000 0.685 0.315
I02.0 Rheumatic chorea with heart involvement
0.000 0.685 0.315
I95.2 Hypotension due to drugs
0.000 0.685 0.314
I34.0 Mitral (valve) insufficiency
0.000 0.686 0.314
I71 Aortic aneurysm and dissection
0.000 0.690 0.310
I49.1 Atrial premature depolarisation
0.000 0.692 0.308
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.694 0.306
I34.1 Mitral (valve) prolapse
0.000 0.694 0.306
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.700 0.300
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.700 0.300
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.700 0.300
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.702 0.298
I95.1 Orthostatic hypotension
0.000 0.704 0.296
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.706 0.294
I49.4 Other and unspecified premature depolarisation
0.000 0.709 0.291
I05.8 Other mitral valve diseases
0.000 0.713 0.286
I05.2 Mitral stenosis with insufficiency
0.000 0.713 0.286
I05.1 Rheumatic mitral insufficiency
0.000 0.713 0.286
I49.0 Ventricular fibrillation and flutter
0.000 0.725 0.275
I51.5 Myocardial degeneration
0.000 0.726 0.274
I51.4 Myocarditis, unspecified
0.000 0.726 0.274
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.726 0.274
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.726 0.274
I51.0 Cardiac septal defect, acquired
0.000 0.726 0.274
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.727 0.273
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.727 0.273
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.727 0.273
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.727 0.273
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.727 0.273
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.727 0.273
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.727 0.273
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.727 0.273
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.727 0.273
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.727 0.273
I68.0 Cerebral amyloid angiopathy
0.000 0.727 0.273
I05.0 Mitral stenosis
0.000 0.728 0.272
I35 Nonrheumatic aortic valve disorders
0.000 0.730 0.270
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.730 0.269
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.735 0.265
I95.0 Idiopathic hypotension
0.000 0.735 0.265
I70 Atherosclerosis
0.000 0.735 0.264
I08.9 Multiple valve disease, unspecified
0.000 0.736 0.264
I73 Other peripheral vascular diseases
0.000 0.738 0.262
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.739 0.261
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.740 0.259
I72 Other aneurysm
0.000 0.743 0.257
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.745 0.255
I61.8 Other intracerebral haemorrhage
0.000 0.748 0.252
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.748 0.252
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.748 0.252
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.748 0.252
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.748 0.252
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.748 0.252
I50.9 Heart failure, unspecified
0.000 0.748 0.252
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.750 0.250
I10-I15 Hypertensive diseases
0.000 0.750 0.249
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.754 0.246
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.754 0.245
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.754 0.245
I97.0 Postcardiotomy syndrome
0.000 0.754 0.245
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.754 0.245
I47.1 Supraventricular tachycardia
0.000 0.755 0.245
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.757 0.243
I49.3 Ventricular premature depolarisation
0.000 0.758 0.242
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.758 0.241
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.760 0.240
I97.1 Other functional disturbances following cardiac surgery
0.000 0.760 0.240
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.765 0.235
I62.1 Nontraumatic extradural haemorrhage
0.000 0.765 0.235
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.766 0.234
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.766 0.234
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.766 0.234
I65.1 Occlusion and stenosis of basilar artery
0.000 0.766 0.234
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.766 0.234
I74.5 Embolism and thrombosis of iliac artery
0.000 0.766 0.234
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.769 0.231
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.769 0.231
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.769 0.231
I98.0 Cardiovascular syphilis
0.000 0.769 0.231
I05.9 Mitral valve disease, unspecified
0.000 0.769 0.231
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.771 0.228
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.772 0.228
I74.8 Embolism and thrombosis of other arteries
0.000 0.772 0.228
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.772 0.228
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.772 0.228
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.772 0.228
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.773 0.227
I08.8 Other multiple valve diseases
0.000 0.775 0.224
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.777 0.223
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.777 0.223
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.777 0.223
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.777 0.223
I71.0 Dissection of aorta [any part]
0.000 0.780 0.220
I60 Subarachnoid haemorrhage
0.000 0.784 0.216
I45.1 Other and unspecified right bundle-branch block
0.000 0.784 0.216
I50.0 Congestive heart failure
0.000 0.788 0.212
I51.6 Cardiovascular disease, unspecified
0.000 0.789 0.211
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.789 0.211
I95.8 Other hypotension
0.000 0.793 0.207
I70.0 Atherosclerosis of aorta
0.000 0.795 0.204
I08.0 Disorders of both mitral and aortic valves
0.000 0.796 0.203
I51.7 Cardiomegaly
0.000 0.798 0.202
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.806 0.193
I79.1 Aortitis in diseases classified elsewhere
0.000 0.806 0.193
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.806 0.193
I35.8 Other aortic valve disorders
0.000 0.809 0.191
I95.9 Hypotension, unspecified
0.000 0.809 0.191
I70.9 Generalised and unspecified atherosclerosis
0.000 0.810 0.190
I70.8 Atherosclerosis of other arteries
0.000 0.810 0.190
I35.9 Aortic valve disorder, unspecified
0.000 0.810 0.190
I73.0 Raynaud's syndrome
0.000 0.811 0.189
I73.8 Other specified peripheral vascular diseases
0.000 0.812 0.188
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.812 0.188
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.812 0.187
I72.3 Aneurysm of iliac artery
0.000 0.813 0.187
I72.0 Aneurysm of carotid artery
0.000 0.813 0.187
I78 Diseases of capillaries
0.000 0.814 0.185
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.815 0.185
I72.9 Aneurysm of unspecified site
0.000 0.815 0.184
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.815 0.184
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.815 0.184
I72.2 Aneurysm of renal artery
0.000 0.815 0.184
I72.1 Aneurysm of artery of upper extremity
0.000 0.815 0.184
I72.8 Aneurysm of other specified arteries
0.000 0.815 0.184
I35.1 Aortic (valve) insufficiency
0.000 0.817 0.183
I11 Hypertensive heart disease
0.000 0.817 0.183
I65.2 Occlusion and stenosis of carotid artery
0.000 0.820 0.180
I13 Hypertensive heart and renal disease
0.000 0.821 0.179
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.822 0.178
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.822 0.178
I15 Secondary hypertension
0.000 0.824 0.176
I51.8 Other ill-defined heart diseases
0.000 0.827 0.173
I73.9 Peripheral vascular disease, unspecified
0.000 0.830 0.170
I70.1 Atherosclerosis of renal artery
0.000 0.830 0.169
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.833 0.167
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.838 0.162
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.838 0.162
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.838 0.162
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.843 0.157
I72.4 Aneurysm of artery of lower extremity
0.000 0.843 0.156
I60.8 Other subarachnoid haemorrhage
0.000 0.845 0.155
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.845 0.155
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.845 0.155
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.845 0.155
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.845 0.155
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.853 0.147
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.854 0.146
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.860 0.140
I77 Other disorders of arteries and arterioles
0.000 0.861 0.139
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.001 0.861 0.138
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.864 0.136
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.864 0.136
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.864 0.136
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.864 0.136
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.864 0.136
I78.9 Disease of capillaries, unspecified
0.000 0.867 0.133
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.867 0.133
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.868 0.131
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.871 0.128
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.871 0.128
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.871 0.128
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.871 0.128
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.872 0.128
I15.9 Seconday hypertension, unspecified
0.000 0.873 0.126
I15.8 Other secondary hypertension
0.000 0.873 0.126
I15.2 Hypertension secondary to endocrine disorders
0.000 0.873 0.126
I15.0 Renovascular hypertension
0.000 0.873 0.126
I15.1 Hypertension secondary to other renal disorders
0.000 0.876 0.124
I12 Hypertensive renal disease
0.000 0.877 0.123
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.001 0.877 0.122
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.878 0.121
Z92.1 Personal history of long-term (current) use of anticoagulants
0.000 0.881 0.119
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.883 0.116
I60.4 Subarachnoid haemorrhage from basilar artery
0.001 0.888 0.111
I35.0 Aortic (valve) stenosis
0.000 0.889 0.111
I78.8 Other diseases of capillaries
0.001 0.893 0.107
I70.10 Atherosclerosis of renal artery (without gangrene)
0.001 0.898 0.101
I77.8 Other specified disorders of arteries and arterioles
0.000 0.899 0.100
I77.5 Necrosis of artery
0.000 0.900 0.100
I77.4 Coeliac artery compression syndrome
0.000 0.900 0.100
I77.3 Arterial fibromuscular dysplasia
0.000 0.900 0.100
I77.2 Rupture of artery
0.000 0.900 0.100
I77.0 Arteriovenous fistula, acquired
0.000 0.900 0.100
I78.1 Naevus, nonneoplastic
0.000 0.911 0.089
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.915 0.084
I67 Other cerebrovascular diseases
0.000 0.919 0.081
I12.0 Hypertensive renal disease with renal failure
0.000 0.920 0.080
I77.1 Stricture of artery
0.000 0.931 0.069
I77.6 Arteritis, unspecified
0.001 0.932 0.067
K08.8 Other specified disorders of teeth and supporting structures
0.066 0.934 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.065 0.935 0.000
K08 Other disorders of teeth and supporting structures
0.064 0.935 0.000
K09 Cysts of oral region, not elsewhere classified
0.062 0.938 0.000
K12 Stomatitis and related lesions
0.061 0.939 0.000
I50.1 Left ventricular failure
0.000 0.940 0.060
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.941 0.058
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.941 0.058
I67.5 Moyamoya disease
0.000 0.941 0.058
I67.4 Hypertensive encephalopathy
0.000 0.941 0.058
I67.3 Progressive vascular leukoencephalopathy
0.000 0.941 0.058
K14 Diseases of tongue
0.058 0.942 0.000
K09.0 Developmental odontogenic cysts
0.058 0.942 0.000
K12.1 Other forms of stomatitis
0.057 0.943 0.000
K08.3 Retained dental root
0.056 0.944 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.944 0.055
K07 Dentofacial anomalies [including malocclusion]
0.054 0.946 0.000
K11 Diseases of salivary glands
0.053 0.947 0.000
K14.8 Other diseases of tongue
0.053 0.947 0.000
K12.3 Oral mucositis (ulcerative)
0.053 0.947 0.000
K09.2 Other cysts of jaw
0.052 0.947 0.000
K00 Disorders of tooth development and eruption
0.052 0.948 0.000
K01 Embedded and impacted teeth
0.052 0.948 0.000
I12.9 Hypertensive renal disease without renal failure
0.001 0.950 0.049
K05 Gingivitis and periodontal diseases
0.049 0.951 0.000
K11.5 Sialolithiasis
0.048 0.952 0.000
K07.3 Anomalies of tooth position
0.047 0.953 0.000
K09.8 Other cysts of oral region, not elsewhere classified
0.047 0.953 0.000
K03 Other diseases of hard tissues of teeth
0.047 0.953 0.000
K12.0 Recurrent oral aphthae
0.046 0.953 0.000
K08.2 Atrophy of edentulous alveolar ridge
0.046 0.953 0.000
K08.0 Exfoliation of teeth due to systemic causes
0.046 0.953 0.000
K09.9 Cyst of oral region, unspecified
0.045 0.955 0.000
K09.1 Developmental (nonodontogenic) cysts of oral region
0.045 0.955 0.000
K14.9 Disease of tongue, unspecified
0.045 0.955 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.044 0.956 0.000
K00.9 Disorder of tooth development, unspecified
0.043 0.957 0.000
I67.2 Cerebral atherosclerosis
0.001 0.957 0.043
K14.0 Glossitis
0.043 0.957 0.000
K08.9 Disorder of teeth and supporting structures, unspecified
0.042 0.958 0.000
K01.1 Impacted teeth
0.042 0.958 0.000
K14.6 Glossodynia
0.042 0.958 0.000
K14.5 Plicated tongue
0.042 0.958 0.000
K14.4 Atrophy of tongue papillae
0.042 0.958 0.000
K14.3 Hypertrophy of tongue papillae
0.042 0.958 0.000
K14.2 Median rhomboid glossitis
0.042 0.958 0.000
K14.1 Geographic tongue
0.042 0.958 0.000
K13 Other diseases of lip and oral mucosa
0.042 0.958 0.000
I67.8 Other specified cerebrovascular diseases
0.000 0.958 0.041
I67.1 Cerebral aneurysm, nonruptured
0.001 0.958 0.041
K07.1 Anomalies of jaw-cranial base relationship
0.041 0.959 0.000
K05.1 Chronic gingivitis
0.039 0.961 0.000
K04 Diseases of pulp and periapical tissues
0.039 0.961 0.000
K07.9 Dentofacial anomaly, unspecified
0.039 0.961 0.000
K07.8 Other dentofacial anomalies
0.039 0.961 0.000
K07.5 Dentofacial functional abnormalities
0.039 0.961 0.000
K07.4 Malocclusion, unspecified
0.039 0.961 0.000
K07.2 Anomalies of dental arch relationship
0.039 0.961 0.000
K07.0 Major anomalies of jaw size
0.039 0.961 0.000
K11.7 Disturbances of salivary secretion
0.038 0.962 0.000
K11.6 Mucocele of salivary gland
0.038 0.962 0.000
K11.4 Fistula of salivary gland
0.038 0.962 0.000
K11.3 Abscess of salivary gland
0.038 0.962 0.000
K11.0 Atrophy of salivary gland
0.038 0.962 0.000
K11.1 Hypertrophy of salivary gland
0.038 0.962 0.000
K11.2 Sialoadenitis
0.038 0.962 0.000
K11.9 Disease of salivary gland, unspecified
0.038 0.962 0.000
K00.8 Other disorders of tooth development
0.037 0.962 0.000
K00.7 Teething syndrome
0.037 0.962 0.000
K00.5 Hereditary disturbances in tooth structure, not elsewhere classified
0.037 0.962 0.000
K00.4 Disturbances in tooth formation
0.037 0.962 0.000
K00.3 Mottled teeth
0.037 0.962 0.000
K00.2 Abnormalities of size and form of teeth
0.037 0.962 0.000
K00.1 Supernumerary teeth
0.037 0.962 0.000
K00.0 Anodontia
0.037 0.962 0.000
K01.0 Embedded teeth
0.037 0.963 0.000
K00.6 Disturbances in tooth eruption
0.037 0.963 0.000
K12.2 Cellulitis and abscess of mouth
0.037 0.963 0.000
K05.3 Chronic periodontitis
0.036 0.964 0.000
K05.2 Acute periodontitis
0.035 0.965 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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