TreeWAS – Variant ID: rs4325129

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E16.2 Hypoglycaemia, unspecified	0.000	0.973	0.027
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.973	0.027
I08.0 Disorders of both mitral and aortic valves	0.000	0.975	0.025
I08 Multiple valve diseases	0.000	0.975	0.025
L81.4 Other melanin hyperpigmentation	0.023	0.977	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.980	0.020
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.981	0.019
I08.9 Multiple valve disease, unspecified	0.000	0.982	0.018
Q61 Cystic kidney disease	0.000	0.985	0.015
Q61.2 Polycystic kidney, adult type	0.000	0.985	0.015
Q61.3 Polycystic kidney, unspecified	0.000	0.986	0.014
I08.8 Other multiple valve diseases	0.000	0.986	0.014
Z01.7 Laboratory examination	0.014	0.986	0.000
Q61.0 Congenital single renal cyst	0.000	0.986	0.014
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.012	0.988	0.000
Z01.8 Other specified special examinations	0.011	0.989	0.000
Q61.8 Other cystic kidney diseases	0.000	0.989	0.011
Q61.4 Renal dysplasia	0.000	0.989	0.011
Q61.1 Polycystic kidney, infantile type	0.000	0.989	0.011
Q61.5 Medullary cystic kidney	0.000	0.989	0.011
E16 Other disorders of pancreatic internal secretion	0.000	0.989	0.011
Z01.4 Gynaecological examination (general)(routine)	0.011	0.989	0.000
Z01.5 Diagnostic skin and sensitisation tests	0.010	0.990	0.000
Q61.9 Cystic kidney disease, unspecified	0.000	0.990	0.010
Z01.9 Special examination, unspecified	0.010	0.990	0.000
L81 Other disorders of pigmentation	0.010	0.990	0.000
Z01.3 Examination of blood pressure	0.009	0.991	0.000
Z01.1 Examination of ears and hearing	0.009	0.991	0.000
Z01.0 Examination of eyes and vision	0.009	0.991	0.000
Q60-Q64 Congenital malformations of the urinary system	0.000	0.991	0.009
M77.12 Lateral epicondylitis (Upper arm)	0.000	0.991	0.009
L81.9 Disorder of pigmentation, unspecified	0.008	0.992	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.992	0.008
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.992	0.008
E16.4 Abnormal secretion of gastrin	0.000	0.992	0.008
E16.3 Increased secretion of glucagon	0.000	0.992	0.008
Z01.2 Dental examination	0.008	0.992	0.000
K04.7 Periapical abscess without sinus	0.008	0.992	0.000
L81.0 Postinflammatory hyperpigmentation	0.007	0.992	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.000	0.992	0.008
E16.1 Other hypoglycaemia	0.000	0.993	0.007
L81.7 Pigmented purpuric dermatosis	0.007	0.993	0.000
L81.6 Other disorders of diminished melanin formation	0.007	0.993	0.000
L81.5 Leukoderma, not elsewhere classified	0.007	0.993	0.000
L81.3 Cafe au lait spots	0.007	0.993	0.000
L81.1 Chloasma	0.007	0.993	0.000
L81.2 Freckles	0.007	0.993	0.000
S82.60 Fracture of lateral malleolus (closed)	0.000	0.993	0.007
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.993	0.007
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.000	0.993	0.007
Q60.0 Renal agenesis, unilateral	0.000	0.993	0.006
Q60.2 Renal agenesis, unspecified	0.000	0.994	0.006
J38.1 Polyp of vocal cord and larynx	0.006	0.994	0.000
Q63 Other congenital malformations of kidney	0.000	0.994	0.006
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.994	0.006
Q64 Other congenital malformations of urinary system	0.000	0.994	0.006
Q60.6 Potter's syndrome	0.000	0.994	0.006
Q60.5 Renal hypoplasia, unspecified	0.000	0.994	0.006
Q60.4 Renal hypoplasia, bilateral	0.000	0.994	0.006
Q60.3 Renal hypoplasia, unilateral	0.000	0.994	0.006
Q60.1 Renal agenesis, bilateral	0.000	0.994	0.006
Q63.1 Lobulated, fused and horseshoe kidney	0.000	0.994	0.006
G80.9 Infantile cerebral palsy, unspecified	0.006	0.994	0.000
Q62.5 Duplication of ureter	0.000	0.995	0.005
Z01.6 Radiological examination, not elsewhere classified	0.005	0.995	0.000
H61.0 Perichondritis of external ear	0.000	0.995	0.005
I61.9 Intracerebral haemorrhage, unspecified	0.005	0.995	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.005	0.995	0.000
I61 Intracerebral haemorrhage	0.005	0.995	0.000
Q62.8 Other congenital malformations of ureter	0.000	0.995	0.005
Q62.7 Congenital vesico-uretero-renal reflux	0.000	0.995	0.005
Q62.6 Malposition of ureter	0.000	0.995	0.005
Q62.4 Agenesis of ureter	0.000	0.995	0.005
Q62.3 Other obstructive defects of renal pelvis and ureter	0.000	0.995	0.005
Q62.2 Congenital megaloureter	0.000	0.995	0.005
Q62.1 Atresia and stenosis of ureter	0.000	0.995	0.005
Q62.0 Congenital hydronephrosis	0.000	0.995	0.005
Q63.9 Congenital malformation of kidney, unspecified	0.000	0.995	0.005
Q63.8 Other specified congenital malformations of kidney	0.000	0.995	0.005
Q63.3 Hyperplastic and giant kidney	0.000	0.995	0.005
L81.8 Other specified disorders of pigmentation	0.004	0.995	0.000
M77.1 Lateral epicondylitis	0.000	0.995	0.005
Q64.9 Congenital malformation of urinary system, unspecified	0.000	0.995	0.004
Q64.8 Other specified congenital malformations of urinary system	0.000	0.995	0.004
Q64.7 Other congenital malformations of bladder and urethra	0.000	0.995	0.004
Q64.6 Congenital diverticulum of bladder	0.000	0.995	0.004
Q64.5 Congenital absence of bladder and urethra	0.000	0.995	0.004
Q64.4 Malformation of urachus	0.000	0.995	0.004
Q64.2 Congenital posterior urethral valves	0.000	0.995	0.004
Q64.1 Exstrophy of urinary bladder	0.000	0.995	0.004
Q64.0 Epispadias	0.000	0.995	0.004
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.005	0.995	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.005	0.995	0.000
Q63.2 Ectopic kidney	0.000	0.995	0.004
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.995	0.004
G80 Infantile cerebral palsy	0.004	0.995	0.000
G83 Other paralytic syndromes	0.004	0.996	0.000
K04.8 Radicular cyst	0.004	0.996	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.000	0.996	0.004
I61.3 Intracerebral haemorrhage in brain stem	0.004	0.996	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.004	0.996	0.000
Z42.1 Follow-up care involving plastic surgery of breast	0.000	0.996	0.004
K04 Diseases of pulp and periapical tissues	0.004	0.996	0.000
L83 Acanthosis nigricans	0.004	0.996	0.000
M54.12 Radiculopathy (Cervical region)	0.000	0.996	0.004
G83.9 Paralytic syndrome, unspecified	0.004	0.996	0.000
I05-I09 Chronic rheumatic heart diseases	0.000	0.996	0.004
G80-G83 Cerebral palsy and other paralytic syndromes	0.004	0.996	0.000
G83.4 Cauda equina syndrome	0.004	0.996	0.000
I61.8 Other intracerebral haemorrhage	0.004	0.996	0.000
S91.3 Open wound of other parts of foot	0.000	0.996	0.004
G83.3 Monoplegia, unspecified	0.004	0.996	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.004	0.996	0.000
G83.2 Monoplegia of upper limb	0.004	0.996	0.000
G83.1 Monoplegia of lower limb	0.004	0.996	0.000
M77.19 Lateral epicondylitis (Site unspecified)	0.000	0.996	0.003
M77.18 Lateral epicondylitis-Other	0.000	0.996	0.003
M77.17 Lateral epicondylitis-Ankle/Foot	0.000	0.996	0.003
M77.16 Lateral epicondylitis (Lower leg)	0.000	0.996	0.003
M77.15 Lateral epicondylitis (Pelvic region and thigh)	0.000	0.996	0.003
M77.14 Lateral epicondylitis-Hand	0.000	0.996	0.003
M77.13 Lateral epicondylitis-Forearm	0.000	0.996	0.003
M77.11 Lateral epicondylitis-Shldr region	0.000	0.996	0.003
M77.10 Lateral epicondylitis (Multiple sites)	0.000	0.996	0.003
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.996	0.004
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.000	0.996	0.004
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.003	0.996	0.000
T42.1 Iminostilbenes	0.000	0.996	0.004
E15 Nondiabetic hypoglycaemic coma	0.000	0.996	0.003
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.996	0.004
G80.4 Ataxic cerebral palsy	0.003	0.996	0.000
G80.3 Dyskinetic cerebral palsy	0.003	0.996	0.000
G80.2 Infantile hemiplegia	0.003	0.996	0.000
G80.1 Spastic diplegia	0.003	0.996	0.000
G80.8 Other infantile cerebral palsy	0.003	0.997	0.000
G83.5 Locked-in syndrome	0.003	0.997	0.000
G83.0 Diplegia of upper limbs	0.003	0.997	0.000
K83.0 Cholangitis	0.003	0.997	0.000
K04.0 Pulpitis	0.003	0.997	0.000
S82.6 Fracture of lateral malleolus	0.000	0.997	0.003
G82 Paraplegia and tetraplegia	0.003	0.997	0.000
K04.6 Periapical abscess with sinus	0.003	0.997	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.000	0.997	0.003
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.997	0.003
I07 Rheumatic tricuspid valve diseases	0.000	0.997	0.003
G80.0 Spastic cerebral palsy	0.003	0.997	0.000
K04.3 Abnormal hard tissue formation in pulp	0.003	0.997	0.000
K04.2 Pulp degeneration	0.003	0.997	0.000
K04.1 Necrosis of pulp	0.003	0.997	0.000
G82.4 Spastic tetraplegia	0.003	0.997	0.000
G83.8 Other specified paralytic syndromes	0.003	0.997	0.000
G81 Hemiplegia	0.003	0.997	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.003	0.997	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.000	0.997	0.003
H61 Other disorders of external ear	0.000	0.997	0.003
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.997	0.003
N93.8 Other specified abnormal uterine and vaginal bleeding	0.003	0.997	0.000
Q63.0 Accessory kidney	0.000	0.997	0.003
Z48.9 Surgical follow-up care, unspecified	0.003	0.997	0.000
K83.8 Other specified diseases of biliary tract	0.003	0.997	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.997	0.003
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.997	0.003
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.997	0.003
H61.3 Acquired stenosis of external ear canal	0.000	0.997	0.003
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.997	0.003
K08.8 Other specified disorders of teeth and supporting structures	0.003	0.997	0.000
G81.9 Hemiplegia, unspecified	0.003	0.997	0.000
H43.8 Other disorders of vitreous body	0.000	0.997	0.003
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.997	0.003
I09 Other rheumatic heart diseases	0.000	0.997	0.003
K83 Other diseases of biliary tract	0.003	0.997	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.997	0.003
S02.10 Fracture of base of skull (closed)	0.003	0.997	0.000
G82.1 Spastic paraplegia	0.003	0.997	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.997	0.003
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.997	0.003
T42.3 Barbiturates	0.000	0.997	0.003
T42.2 Succinimides and oxazolidinediones	0.000	0.997	0.003
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.997	0.003
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.997	0.003
I07.1 Tricuspid insufficiency	0.000	0.997	0.003
K83.1 Obstruction of bile duct	0.003	0.997	0.000
H61.8 Other specified disorders of external ear	0.000	0.997	0.003
I06 Rheumatic aortic valve diseases	0.000	0.997	0.002
M43.06 Spondylolysis (Lumbar region)	0.003	0.997	0.000
S82.61 Fracture of lateral malleolus (open)	0.000	0.997	0.003
G82.3 Flaccid tetraplegia	0.003	0.997	0.000
G82.0 Flaccid paraplegia	0.003	0.997	0.000
M43.0 Spondylolysis	0.003	0.997	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
T42.4 Benzodiazepines	0.000	0.997	0.003
I07.9 Tricuspid valve disease, unspecified	0.000	0.997	0.002
I07.8 Other tricuspid valve diseases	0.000	0.997	0.002
I07.2 Tricuspid stenosis with insufficiency	0.000	0.997	0.002
I07.0 Tricuspid stenosis	0.000	0.997	0.002
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
C69.3 Choroid	0.000	0.997	0.003
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.997	0.002
T46.1 Calcium-channel blockers	0.000	0.997	0.003
G81.0 Flaccid hemiplegia	0.002	0.997	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.997	0.003
G82.5 Tetraplegia, unspecified	0.002	0.997	0.000
H61.1 Non-infective disorders of pinna	0.000	0.997	0.002
K83.3 Fistula of bile duct	0.002	0.997	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.002
T40.6 Other and unspecified narcotics	0.000	0.997	0.002
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.997	0.002
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.997	0.002
C48.2 Peritoneum, unspecified	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.002
M43.09 Spondylolysis (Site unspecified)	0.002	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.998	0.002
M54.1 Radiculopathy	0.000	0.998	0.002
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.998	0.002
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.998	0.002
T47.7 Emetics	0.000	0.998	0.002
T47.6 Antidiarrhoeal drugs	0.000	0.998	0.002
T47.5 Digestants	0.000	0.998	0.002
T47.4 Other laxatives	0.000	0.998	0.002
T47.3 Saline and osmotic laxatives	0.000	0.998	0.002
T47.2 Stimulant laxatives	0.000	0.998	0.002
T47.0 Histamine H(2)-receptor antagonists	0.000	0.998	0.002
T50.7 Analeptics and opioid receptor antagonists	0.000	0.998	0.002
T50.5 Appetite depressants	0.000	0.998	0.002
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.998	0.002
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.998	0.002
T50.1 Loop [high-ceiling] diuretics	0.000	0.998	0.002
T50.0 Mineralocorticoids and their antagonists	0.000	0.998	0.002
M43.16 Spondylolisthesis (Lumbar region)	0.002	0.998	0.000
K04.5 Chronic apical periodontitis	0.002	0.998	0.000
T38.9 Other and unspecified hormone antagonists	0.000	0.998	0.002
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.998	0.002
T38.7 Androgens and anabolic congeners	0.000	0.998	0.002
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.998	0.002
T38.5 Other oestrogens and progestogens	0.000	0.998	0.002
T38.4 Oral contraceptives	0.000	0.998	0.002
T38.2 Antithyroid drugs	0.000	0.998	0.002
T38.1 Thyroid hormones and substitutes	0.000	0.998	0.002
T38.0 Glucocorticoids and synthetic analogues	0.000	0.998	0.002
T42.0 Hydantoin derivatives	0.000	0.998	0.002
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.998	0.002
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
M43.02 Spondylolysis (Cervical region)	0.002	0.998	0.000
T50.4 Drugs affecting uric acid metabolism	0.000	0.998	0.002
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.998	0.002
M54.16 Radiculopathy (Lumbar region)	0.000	0.998	0.002
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.998	0.002
T36 Poisoning by systemic antibiotics	0.000	0.998	0.002
G82.2 Paraplegia, unspecified	0.002	0.998	0.000
I09.8 Other specified rheumatic heart diseases	0.000	0.998	0.002
I09.2 Chronic rheumatic pericarditis	0.000	0.998	0.002
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.998	0.002
I09.0 Rheumatic myocarditis	0.000	0.998	0.002
K83.5 Biliary cyst	0.002	0.998	0.000
K83.4 Spasm of sphincter of Oddi	0.002	0.998	0.000
K83.2 Perforation of bile duct	0.002	0.998	0.000
Z85.3 Personal history of malignant neoplasm of breast	0.000	0.998	0.002
H52.3 Anisometropia and aniseikonia	0.000	0.998	0.002
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.998	0.002
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.998	0.002
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.998	0.002
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.998	0.002
T44.0 Anticholinesterase agents	0.000	0.998	0.002
M54.17 Radiculopathy (Lumbosacral region)	0.000	0.998	0.002
K04.4 Acute apical periodontitis of pulpal origin	0.002	0.998	0.000
M43 Other deforming dorsopathies	0.002	0.998	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.002	0.998	0.000
M43.1 Spondylolisthesis	0.002	0.998	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.998	0.002
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.998	0.002
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.998	0.002
T46.7 Peripheral vasodilators	0.000	0.998	0.002
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.998	0.002
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.998	0.002
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.998	0.002
H61.9 Disorder of external ear, unspecified	0.000	0.998	0.002
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.998	0.002
I06.8 Other rheumatic aortic valve diseases	0.000	0.998	0.002
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.998	0.002
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
H61.2 Impacted cerumen	0.000	0.998	0.002
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.002	0.998	0.000
M43.08 Spondylolysis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M43.07 Spondylolysis (Lumbosacral region)	0.002	0.998	0.000
M43.05 Spondylolysis (Thoracolumbar region)	0.002	0.998	0.000
M43.04 Spondylolysis (Thoracic region)	0.002	0.998	0.000
M43.03 Spondylolysis (Cervicothoracic region)	0.002	0.998	0.000
M43.01 Spondylolysis (Occipito-atlanto-axial region)	0.002	0.998	0.000
M43.00 Spondylolysis (Multiple sites in spine)	0.002	0.998	0.000
D37.7 Other digestive organs	0.002	0.998	0.000
G81.1 Spastic hemiplegia	0.002	0.998	0.000
S80.0 Contusion of knee	0.000	0.998	0.002
I60 Subarachnoid haemorrhage	0.002	0.998	0.000
M43.2 Other fusion of spine	0.002	0.998	0.000
I06.1 Rheumatic aortic insufficiency	0.000	0.998	0.002
T45.2 Vitamins, not elsewhere classified	0.000	0.998	0.002
T50.8 Diagnostic agents	0.000	0.998	0.002
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.002	0.998	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.998	0.002
T40.8 Lysergide [LSD]	0.000	0.998	0.002
T40.7 Cannabis (derivatives)	0.000	0.998	0.002
T40.5 Cocaine	0.000	0.998	0.002
T40.3 Methadone	0.000	0.998	0.002
T40.1 Heroin	0.000	0.998	0.002
T40.0 Opium	0.000	0.998	0.002
Z29.1 Prophylactic immunotherapy	0.002	0.998	0.000
J95.8 Other postprocedural respiratory disorders	0.002	0.998	0.000
M43.6 Torticollis	0.002	0.998	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
T41.5 Therapeutic gases	0.000	0.998	0.002
T41.4 Anaesthetic, unspecified	0.000	0.998	0.002
T41.3 Local anaesthetics	0.000	0.998	0.002
T41.2 Other and unspecified general anaesthetics	0.000	0.998	0.002
T41.1 Intravenous anaesthetics	0.000	0.998	0.002
T41.0 Inhaled anaesthetics	0.000	0.998	0.002
T49.9 Topical agent, unspecified	0.000	0.998	0.002
T49.8 Other topical agents	0.000	0.998	0.002
T49.7 Dental drugs, topically applied	0.000	0.998	0.002
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.998	0.002
T49.5 Ophthalmological drugs and preparations	0.000	0.998	0.002
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.998	0.002
T49.3 Emollients, demulcents and protectants	0.000	0.998	0.002
T49.2 Local astringents and local detergents	0.000	0.998	0.002
T49.1 Antipruritics	0.000	0.998	0.002
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.998	0.002
M43.29 Other fusion of spine (Site unspecified)	0.002	0.998	0.000
Z29.2 Other prophylactic chemotherapy	0.002	0.998	0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.002	0.998	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.998	0.002
T37.5 Antiviral drugs	0.000	0.998	0.002
T37.4 Anthelminthics	0.000	0.998	0.002
T37.3 Other antiprotozoal drugs	0.000	0.998	0.002
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.998	0.002
T37.1 Antimycobacterial drugs	0.000	0.998	0.002
T37.0 Sulphonamides	0.000	0.998	0.002
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.998	0.002
M54.15 Radiculopathy (Thoracolumbar region)	0.000	0.998	0.002
M54.13 Radiculopathy (Cervicothoracic region)	0.000	0.998	0.002
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.000	0.998	0.002
M54.10 Radiculopathy (Multiple sites in spine)	0.000	0.998	0.002
T45.5 Anticoagulants	0.000	0.998	0.002
I09.9 Rheumatic heart disease, unspecified	0.000	0.998	0.002
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.002	0.998	0.000
T40.4 Other synthetic narcotics	0.000	0.998	0.002
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.998	0.002
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.998	0.002
T48.5 Anti-common-cold drugs	0.000	0.998	0.002
T48.4 Expectorants	0.000	0.998	0.002
T48.3 Antitussives	0.000	0.998	0.002
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.998	0.002
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.998	0.002
T48.0 Oxytocic drugs	0.000	0.998	0.002
M54.14 Radiculopathy (Thoracic region)	0.000	0.998	0.002
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.000	0.998	0.002
Z39.0 Care and examination immediately after delivery	0.000	0.998	0.002
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.998	0.002
E22 Hyperfunction of pituitary gland	0.000	0.998	0.002
T36.9 Systemic antibiotic, unspecified	0.000	0.998	0.002
T36.8 Other systemic antibiotics	0.000	0.998	0.002
T36.7 Antifungal antibiotics, systemically used	0.000	0.998	0.002
T36.6 Rifamycins	0.000	0.998	0.002
T36.5 Aminoglycosides	0.000	0.998	0.002
T36.3 Macrolides	0.000	0.998	0.002
T36.2 Chloramphenicol group	0.000	0.998	0.002
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.998	0.002
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.998	0.002
T45.8 Other primarily systemic and haematological agents	0.000	0.998	0.002
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.998	0.002
T45.6 Fibrinolysis-affecting drugs	0.000	0.998	0.002
T45.4 Iron and its compounds	0.000	0.998	0.002
T45.3 Enzymes, not elsewhere classified	0.000	0.998	0.002
M43.62 Torticollis-Cervical	0.002	0.998	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.998	0.002
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
I06.0 Rheumatic aortic stenosis	0.000	0.998	0.001
M43.9 Deforming dorsopathy, unspecified	0.002	0.998	0.000
M43.8 Other specified deforming dorsopathies	0.002	0.998	0.000
M43.5 Other recurrent vertebral subluxation	0.002	0.998	0.000
M43.4 Other recurrent atlantoaxial subluxation	0.002	0.998	0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy	0.002	0.998	0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M43.15 Spondylolisthesis (Thoracolumbar region)	0.002	0.998	0.000
M43.14 Spondylolisthesis (Thoracic region)	0.002	0.998	0.000
M43.13 Spondylolisthesis (Cervicothoracic region)	0.002	0.998	0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.002	0.998	0.000
M43.10 Spondylolisthesis (Multiple sites in spine)	0.002	0.998	0.000
T36.0 Penicillins	0.000	0.998	0.002
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.998	0.002
T39.4 Antirheumatics, not elsewhere classified	0.000	0.998	0.002
T39.2 Pyrazolone derivatives	0.000	0.998	0.002
M77 Other enthesopathies	0.000	0.998	0.002
I60.8 Other subarachnoid haemorrhage	0.002	0.998	0.000
L43.9 Lichen planus, unspecified	0.002	0.998	0.000
M43.12 Spondylolisthesis (Cervical region)	0.002	0.998	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.000	0.998	0.002
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.998	0.002
K83.9 Disease of biliary tract, unspecified	0.002	0.998	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.998	0.002
T85.4 Mechanical complication of breast prosthesis and implant	0.000	0.998	0.002
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
M43.17 Spondylolisthesis (Lumbosacral region)	0.002	0.998	0.000
M54.19 Radiculopathy (Site unspecified)	0.000	0.998	0.002
I60.5 Subarachnoid haemorrhage from vertebral artery	0.002	0.998	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.002	0.998	0.000
M77.0 Medial epicondylitis	0.000	0.998	0.002
M77.02 Medial epicondylitis (Upper arm)	0.000	0.998	0.002
M22.4 Chondromalacia patellae	0.000	0.998	0.002
M43.28 Other fusion of spine (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M43.27 Other fusion of spine (Lumbosacral region)	0.002	0.998	0.000
M43.26 Other fusion of spine (Lumbar region)	0.002	0.998	0.000
M43.25 Other fusion of spine (Thoracolumbar region)	0.002	0.998	0.000
M43.24 Other fusion of spine (Thoracic region)	0.002	0.998	0.000
M43.23 Other fusion of spine (Cervicothoracic region)	0.002	0.998	0.000
M43.22 Other fusion of spine (Cervical region)	0.002	0.998	0.000
M43.21 Other fusion of spine (Occipito-atlanto-axial region)	0.002	0.998	0.000
M43.20 Other fusion of spine (Multiple sites in spine)	0.002	0.998	0.000
T36.4 Tetracyclines	0.000	0.998	0.002
M43.69 Torticollis-Site unspe	0.002	0.998	0.000
M43.68 Torticollis-Sacral/sacrococ	0.002	0.998	0.000
M43.67 Torticollis-Lumbosacral	0.002	0.998	0.000
M43.66 Torticollis-Lumbar	0.002	0.998	0.000
M43.65 Torticollis-Thoracolumbar	0.002	0.998	0.000
M43.64 Torticollis-Thoracic	0.002	0.998	0.000
M43.63 Torticollis-Cervicothoracic	0.002	0.998	0.000
M43.61 Torticollis-Occipit-atl-axl	0.002	0.998	0.000
M43.60 Torticollis-Mult site	0.002	0.998	0.000
Z39.1 Care and examination of lactating mother	0.000	0.998	0.002
M43.19 Spondylolisthesis (Site unspecified)	0.002	0.998	0.000
S02.60 Fracture of mandible (closed)	0.002	0.998	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.000	0.998	0.002
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.998	0.002
T39.1 4-Aminophenol derivatives	0.000	0.998	0.002
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.998	0.002
M77.4 Metatarsalgia	0.000	0.998	0.002
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
Z29.8 Other specified prophylactic measures	0.002	0.998	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.000	0.998	0.002
Z29 Need for other prophylactic measures	0.002	0.998	0.000
T40.2 Other opioids	0.000	0.998	0.002
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.998	0.001
E22.8 Other hyperfunction of pituitary gland	0.000	0.998	0.001
H65.4 Other chronic nonsuppurative otitis media	0.000	0.998	0.002
I60.4 Subarachnoid haemorrhage from basilar artery	0.002	0.998	0.000
J92.0 Pleural plaque with presence of asbestos	0.000	0.998	0.002
S02.1 Fracture of base of skull	0.002	0.998	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.998	0.002
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.002	0.998	0.000
T45.0 Antiallergic and antiemetic drugs	0.000	0.998	0.002
M43.39 Recurrent atlantoaxial subluxation with myelopathy (Site unspecified)	0.001	0.998	0.000
M43.38 Recurrent atlantoaxial subluxation with myelopathy (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M43.37 Recurrent atlantoaxial subluxation with myelopathy (Lumbosacral region)	0.001	0.998	0.000
M43.36 Recurrent atlantoaxial subluxation with myelopathy (Lumbar region)	0.001	0.998	0.000
M43.35 Recurrent atlantoaxial subluxation with myelopathy (Thoracolumbar region)	0.001	0.998	0.000
M43.34 Recurrent atlantoaxial subluxation with myelopathy (Thoracic region)	0.001	0.998	0.000
M43.33 Recurrent atlantoaxial subluxation with myelopathy (Cervicothoracic region)	0.001	0.998	0.000
M43.32 Recurrent atlantoaxial subluxation with myelopathy (Cervical region)	0.001	0.998	0.000
M43.31 Recurrent atlantoaxial subluxation with myelopathy (Occipito-atlanto-axial region)	0.001	0.998	0.000
M43.30 Recurrent atlantoaxial subluxation with myelopathy (Multiple sites in spine)	0.001	0.998	0.000
M43.49 Other recurrent atlantoaxial subluxation-Site unspe	0.001	0.998	0.000
M43.48 Other recurrent atlantoaxial subluxation-Sacral/sacrococ	0.001	0.998	0.000
M43.47 Other recurrent atlantoaxial subluxation-Lumbosacral	0.001	0.998	0.000
M43.46 Other recurrent atlantoaxial subluxation-Lumbar	0.001	0.998	0.000
M43.45 Other recurrent atlantoaxial subluxation-Thoracolumbar	0.001	0.998	0.000
M43.44 Other recurrent atlantoaxial subluxation-Thoracic	0.001	0.998	0.000
M43.43 Other recurrent atlantoaxial subluxation-Cervicothoracic	0.001	0.998	0.000
M43.42 Other recurrent atlantoaxial subluxation-Cervical	0.001	0.998	0.000
M43.41 Other recurrent atlantoaxial subluxation-Occipit-atl-axl	0.001	0.998	0.000
M43.40 Other recurrent atlantoaxial subluxation-Mult site	0.001	0.998	0.000
M43.59 Other recurrent vertebral subluxation (Site unspecified)	0.001	0.998	0.000
M43.58 Other recurrent vertebral subluxation (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M43.57 Other recurrent vertebral subluxation (Lumbosacral region)	0.001	0.998	0.000
M43.56 Other recurrent vertebral subluxation (Lumbar region)	0.001	0.998	0.000
M43.55 Other recurrent vertebral subluxation (Thoracolumbar region)	0.001	0.998	0.000
M43.54 Other recurrent vertebral subluxation (Thoracic region)	0.001	0.998	0.000
M43.53 Other recurrent vertebral subluxation (Cervicothoracic region)	0.001	0.998	0.000
M43.52 Other recurrent vertebral subluxation (Cervical region)	0.001	0.998	0.000
M43.51 Other recurrent vertebral subluxation-Occipit-atl-axl	0.001	0.998	0.000
M43.50 Other recurrent vertebral subluxation (Multiple sites in spine)	0.001	0.998	0.000
M43.89 Other specified deforming dorsopathies (Site unspecified)	0.001	0.998	0.000
M43.88 Other specified deforming dorsopathies (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M43.87 Other specified deforming dorsopathies (Lumbosacral region)	0.001	0.998	0.000
M43.86 Other specified deforming dorsopathies (Lumbar region)	0.001	0.998	0.000
M43.85 Other specified deforming dorsopathies (Thoracolumbar region)	0.001	0.998	0.000
M43.84 Other specified deforming dorsopathies (Thoracic region)	0.001	0.998	0.000
M43.83 Other specified deforming dorsopathies (Cervicothoracic region)	0.001	0.998	0.000
M43.82 Other specified deforming dorsopathies (Cervical region)	0.001	0.998	0.000
M43.81 Other specified deforming dorsopathies (Occipito-atlanto-axial region)	0.001	0.998	0.000
M43.80 Other specified deforming dorsopathies (Multiple sites in spine)	0.001	0.998	0.000
M43.99 Deforming dorsopathy, unspecified (Site unspecified)	0.001	0.998	0.000
M43.98 Deforming dorsopathy, unspecified (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M43.97 Deforming dorsopathy, unspecified (Lumbosacral region)	0.001	0.998	0.000
M43.96 Deforming dorsopathy, unspecified (Lumbar region)	0.001	0.998	0.000
M43.95 Deforming dorsopathy, unspecified (Thoracolumbar region)	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations