TreeWAS – Variant ID: rs4332037

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E11.9 Without complications	0.000	0.249	0.751
E11 Non-insulin-dependent diabetes mellitus	0.000	0.256	0.744
E11.4 With neurological complications	0.000	0.292	0.708
E11.5 With peripheral circulatory complications	0.000	0.301	0.699
M54 Dorsalgia	0.000	0.330	0.670
M54.3 Sciatica	0.000	0.330	0.670
E11.2 With renal complications	0.000	0.333	0.667
M54.5 Low back pain	0.000	0.343	0.657
M54.39 Sciatica (Site unspecified)	0.000	0.345	0.655
M54.2 Cervicalgia	0.000	0.353	0.647
M54.22 Cervicalgia (Cervical region)	0.000	0.369	0.631
E11.8 With unspecified complications	0.000	0.371	0.629
M54.9 Dorsalgia, unspecified	0.000	0.382	0.618
M54.59 Low back pain (Site unspecified)	0.000	0.385	0.615
M54.56 Low back pain (Lumbar region)	0.000	0.408	0.592
M54.37 Sciatica (Lumbosacral region)	0.000	0.414	0.586
M54.57 Low back pain (Lumbosacral region)	0.000	0.420	0.580
E11.0 With coma	0.000	0.426	0.574
M54.36 Sciatica (Lumbar region)	0.000	0.426	0.574
E11.6 With other specified complications	0.000	0.431	0.569
M54.94 Dorsalgia, unspecified (Thoracic region)	0.000	0.453	0.547
E11.1 With ketoacidosis	0.000	0.455	0.545
E11.7 With multiple complications	0.000	0.467	0.533
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.000	0.485	0.515
M54.50 Low back pain (Multiple sites in spine)	0.000	0.490	0.510
M54.29 Cervicalgia-Site unspe	0.000	0.499	0.501
M54.99 Dorsalgia, unspecified (Site unspecified)	0.000	0.509	0.491
M54.23 Cervicalgia (Cervicothoracic region)	0.000	0.516	0.484
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.000	0.519	0.481
M54.0 Panniculitis affecting regions of neck and back	0.000	0.519	0.481
M54.96 Dorsalgia, unspecified (Lumbar region)	0.000	0.520	0.480
M54.35 Sciatica (Thoracolumbar region)	0.000	0.520	0.480
M54.34 Sciatica-Thoracic	0.000	0.520	0.480
M54.33 Sciatica-Cervicothoracic	0.000	0.520	0.480
M54.32 Sciatica-Cervical	0.000	0.520	0.480
M54.31 Sciatica-Occipit-atl-axl	0.000	0.520	0.480
M54.30 Sciatica (Multiple sites in spine)	0.000	0.520	0.480
M54.54 Low back pain-Thoracic	0.000	0.529	0.471
M54.53 Low back pain-Cervicothoracic	0.000	0.529	0.471
M54.52 Low back pain-Cervical	0.000	0.529	0.471
M54.51 Low back pain-Occipit-atl-axl	0.000	0.529	0.471
M54.28 Cervicalgia-Sacral/sacrococ	0.000	0.536	0.464
M54.27 Cervicalgia-Lumbosacral	0.000	0.536	0.464
M54.26 Cervicalgia-Lumbar	0.000	0.536	0.464
M54.25 Cervicalgia-Thoracolumbar	0.000	0.536	0.464
M54.24 Cervicalgia-Thoracic	0.000	0.536	0.464
M54.20 Cervicalgia-Mult site	0.000	0.536	0.464
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.000	0.536	0.463
M54.1 Radiculopathy	0.000	0.538	0.462
M54.4 Lumbago with sciatica	0.000	0.544	0.456
M54.55 Low back pain (Thoracolumbar region)	0.000	0.547	0.453
M54.8 Other dorsalgia	0.000	0.556	0.444
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.000	0.557	0.443
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.000	0.557	0.443
M54.92 Dorsalgia, unspecified (Cervical region)	0.000	0.560	0.440
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.000	0.575	0.425
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.000	0.597	0.403
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.000	0.609	0.390
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.000	0.611	0.389
M54.12 Radiculopathy (Cervical region)	0.000	0.615	0.385
M54.46 Lumbago with sciatica (Lumbar region)	0.000	0.649	0.350
M54.49 Lumbago with sciatica (Site unspecified)	0.000	0.652	0.348
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)	0.000	0.655	0.345
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)	0.000	0.655	0.345
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)	0.000	0.655	0.345
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)	0.000	0.655	0.345
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)	0.000	0.655	0.345
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)	0.000	0.655	0.345
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)	0.000	0.655	0.345
M54.02 Panniculitis affecting regions of neck and back (Cervical region)	0.000	0.655	0.345
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)	0.000	0.655	0.345
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)	0.000	0.655	0.345
M54.6 Pain in thoracic spine	0.001	0.655	0.344
M54.15 Radiculopathy (Thoracolumbar region)	0.000	0.669	0.331
M54.14 Radiculopathy (Thoracic region)	0.000	0.669	0.331
M54.13 Radiculopathy (Cervicothoracic region)	0.000	0.669	0.331
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.000	0.669	0.331
M54.10 Radiculopathy (Multiple sites in spine)	0.000	0.669	0.331
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.000	0.673	0.327
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.000	0.673	0.327
M54.44 Lumbago with sciatica-Thoracic	0.000	0.673	0.327
M54.43 Lumbago with sciatica-Cervicothoracic	0.000	0.673	0.327
M54.42 Lumbago with sciatica-Cervical	0.000	0.673	0.327
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.000	0.673	0.327
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.000	0.673	0.327
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.000	0.676	0.324
M50-M54 Other dorsopathies	0.000	0.680	0.320
M54.19 Radiculopathy (Site unspecified)	0.000	0.681	0.319
M54.17 Radiculopathy (Lumbosacral region)	0.000	0.681	0.319
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)	0.000	0.682	0.318
M54.87 Other dorsalgia (Lumbosacral region)	0.000	0.682	0.318
M54.85 Other dorsalgia (Thoracolumbar region)	0.000	0.682	0.318
M54.84 Other dorsalgia (Thoracic region)	0.000	0.682	0.318
M54.83 Other dorsalgia (Cervicothoracic region)	0.000	0.682	0.318
M54.82 Other dorsalgia (Cervical region)	0.000	0.682	0.318
M54.81 Other dorsalgia (Occipito-atlanto-axial region)	0.000	0.682	0.318
M54.80 Other dorsalgia (Multiple sites in spine)	0.000	0.682	0.318
M54.89 Other dorsalgia (Site unspecified)	0.000	0.685	0.315
M54.86 Other dorsalgia (Lumbar region)	0.000	0.714	0.285
M53 Other dorsopathies, not elsewhere classified	0.000	0.724	0.276
M50 Cervical disk disorders	0.000	0.744	0.256
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.000	0.745	0.255
M54.69 Pain in thoracic spine-Site unspe	0.001	0.753	0.247
M54.68 Pain in thoracic spine-Sacral/sacrococ	0.001	0.753	0.247
M54.67 Pain in thoracic spine-Lumbosacral	0.001	0.753	0.247
M54.66 Pain in thoracic spine-Lumbar	0.001	0.753	0.247
M54.65 Pain in thoracic spine (Thoracolumbar region)	0.001	0.753	0.247
M54.63 Pain in thoracic spine (Cervicothoracic region)	0.001	0.753	0.247
M54.62 Pain in thoracic spine-Cervical	0.001	0.753	0.247
M54.61 Pain in thoracic spine-Occipit-atl-axl	0.001	0.753	0.247
M54.60 Pain in thoracic spine (Multiple sites in spine)	0.001	0.753	0.247
E11.3 With ophthalmic complications	0.000	0.755	0.245
M50.1 Cervical disk disorder with radiculopathy	0.000	0.760	0.240
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.000	0.760	0.240
M54.47 Lumbago with sciatica (Lumbosacral region)	0.000	0.767	0.233
M50.0 Cervical disk disorder with myelopathy	0.000	0.787	0.213
M53.8 Other specified dorsopathies	0.000	0.802	0.198
M53.2 Spinal instabilities	0.000	0.802	0.198
M53.1 Cervicobrachial syndrome	0.000	0.802	0.198
M53.0 Cervicocranial syndrome	0.000	0.802	0.198
M50.8 Other cervical disk disorders	0.000	0.816	0.184
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns	0.000	0.817	0.183
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac	0.000	0.817	0.183
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar	0.000	0.817	0.183
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol	0.000	0.817	0.183
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic	0.000	0.817	0.183
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot	0.000	0.817	0.183
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical	0.000	0.817	0.183
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-	0.000	0.817	0.183
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit	0.000	0.817	0.183
E10-E14 Diabetes mellitus	0.000	0.826	0.174
M53.9 Dorsopathy, unspecified	0.000	0.836	0.164
M50.9 Cervical disk disorder, unspecified	0.000	0.841	0.159
M50.3 Other cervical disk degeneration	0.000	0.850	0.150
M53.09 Cervicocranial syndrome-Site unspe	0.000	0.858	0.142
M53.08 Cervicocranial syndrome-Sacral/sacrococ	0.000	0.858	0.142
M53.07 Cervicocranial syndrome-Lumbosacral	0.000	0.858	0.142
M53.06 Cervicocranial syndrome-Lumbar	0.000	0.858	0.142
M53.05 Cervicocranial syndrome-Thoracolumbar	0.000	0.858	0.142
M53.04 Cervicocranial syndrome-Thoracic	0.000	0.858	0.142
M53.03 Cervicocranial syndrome (Cervicothoracic region)	0.000	0.858	0.142
M53.02 Cervicocranial syndrome (Cervical region)	0.000	0.858	0.142
M53.01 Cervicocranial syndrome (Occipito-atlanto-axial region)	0.000	0.858	0.142
M53.00 Cervicocranial syndrome (Multiple sites in spine)	0.000	0.858	0.142
M53.19 Cervicobrachial syndrome-Site unspe	0.000	0.858	0.142
M53.18 Cervicobrachial syndrome-Sacral/sacrococ	0.000	0.858	0.142
M53.17 Cervicobrachial syndrome-Lumbosacral	0.000	0.858	0.142
M53.16 Cervicobrachial syndrome-Lumbar	0.000	0.858	0.142
M53.15 Cervicobrachial syndrome-Thoracolumbar	0.000	0.858	0.142
M53.14 Cervicobrachial syndrome-Thoracic	0.000	0.858	0.142
M53.13 Cervicobrachial syndrome (Cervicothoracic region)	0.000	0.858	0.142
M53.12 Cervicobrachial syndrome (Cervical region)	0.000	0.858	0.142
M53.11 Cervicobrachial syndrome (Occipito-atlanto-axial region)	0.000	0.858	0.142
M53.10 Cervicobrachial syndrome (Multiple sites in spine)	0.000	0.858	0.142
M53.29 Spinal instabilities (Site unspecified)	0.000	0.858	0.142
M53.28 Spinal instabilities (Sacral and sacrococcygeal region)	0.000	0.858	0.142
M53.27 Spinal instabilities (Lumbosacral region)	0.000	0.858	0.142
M53.26 Spinal instabilities (Lumbar region)	0.000	0.858	0.142
M53.25 Spinal instabilities (Thoracolumbar region)	0.000	0.858	0.142
M53.24 Spinal instabilities (Thoracic region)	0.000	0.858	0.142
M53.23 Spinal instabilities (Cervicothoracic region)	0.000	0.858	0.142
M53.22 Spinal instabilities (Cervical region)	0.000	0.858	0.142
M53.21 Spinal instabilities (Occipito-atlanto-axial region)	0.000	0.858	0.142
M53.20 Spinal instabilities (Multiple sites in spine)	0.000	0.858	0.142
M53.89 Other specified dorsopathies (Site unspecified)	0.000	0.858	0.142
M53.88 Other specified dorsopathies (Sacral and sacrococcygeal region)	0.000	0.858	0.142
M53.87 Other specified dorsopathies (Lumbosacral region)	0.000	0.858	0.142
M53.86 Other specified dorsopathies (Lumbar region)	0.000	0.858	0.142
M53.85 Other specified dorsopathies (Thoracolumbar region)	0.000	0.858	0.142
M53.84 Other specified dorsopathies (Thoracic region)	0.000	0.858	0.142
M53.83 Other specified dorsopathies (Cervicothoracic region)	0.000	0.858	0.142
M53.82 Other specified dorsopathies (Cervical region)	0.000	0.858	0.142
M53.81 Other specified dorsopathies (Occipito-atlanto-axial region)	0.000	0.858	0.142
M53.80 Other specified dorsopathies (Multiple sites in spine)	0.000	0.858	0.142
E12 Malnutrition-related diabetes mellitus	0.000	0.875	0.125
E10 Insulin-dependent diabetes mellitus	0.000	0.881	0.119
M53.99 Dorsopathy, unspecified (Site unspecified)	0.000	0.882	0.118
M53.98 Dorsopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.882	0.118
M53.97 Dorsopathy, unspecified (Lumbosacral region)	0.000	0.882	0.118
M53.95 Dorsopathy, unspecified (Thoracolumbar region)	0.000	0.882	0.118
M53.94 Dorsopathy, unspecified (Thoracic region)	0.000	0.882	0.118
M53.93 Dorsopathy, unspecified (Cervicothoracic region)	0.000	0.882	0.118
M53.92 Dorsopathy, unspecified (Cervical region)	0.000	0.882	0.118
M53.91 Dorsopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.882	0.118
M53.90 Dorsopathy, unspecified (Multiple sites in spine)	0.000	0.882	0.118
M51 Other intervertebral disk disorders	0.000	0.888	0.112
M54.64 Pain in thoracic spine (Thoracic region)	0.001	0.889	0.110
E13 Other specified diabetes mellitus	0.000	0.889	0.111
M51.8 Other specified intervertebral disk disorders	0.000	0.896	0.104
E10.8 With unspecified complications	0.000	0.897	0.103
E10.0 With coma	0.000	0.897	0.103
E10.5 With peripheral circulatory complications	0.000	0.901	0.099
E12.9 Without complications	0.000	0.910	0.090
E12.8 With unspecified complications	0.000	0.910	0.090
E12.7 With multiple complications	0.000	0.910	0.090
E12.6 With other specified complications	0.000	0.910	0.090
E12.5 With peripheral circulatory complications	0.000	0.910	0.090
E12.4 With neurological complications	0.000	0.910	0.090
E12.3 With ophthalmic complications	0.000	0.910	0.090
E12.2 With renal complications	0.000	0.910	0.090
E12.1 With ketoacidosis	0.000	0.910	0.090
E12.0 With coma	0.000	0.910	0.090
E10.2 With renal complications	0.000	0.913	0.087
M54.16 Radiculopathy (Lumbar region)	0.001	0.914	0.085
E10.7 With multiple complications	0.000	0.914	0.085
M50.2 Other cervical disk displacement	0.000	0.915	0.085
M53.96 Dorsopathy, unspecified (Lumbar region)	0.001	0.916	0.084
E66.9 Obesity, unspecified	0.000	0.918	0.082
E10.6 With other specified complications	0.000	0.918	0.082
M51.3 Other specified intervertebral disk degeneration	0.000	0.919	0.080
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.000	0.919	0.080
E13.8 With unspecified complications	0.000	0.920	0.080
E13.7 With multiple complications	0.000	0.920	0.080
E13.6 With other specified complications	0.000	0.920	0.080
E13.5 With peripheral circulatory complications	0.000	0.920	0.080
E13.4 With neurological complications	0.000	0.920	0.080
E13.3 With ophthalmic complications	0.000	0.920	0.080
E13.2 With renal complications	0.000	0.920	0.080
E13.1 With ketoacidosis	0.000	0.920	0.080
E13.0 With coma	0.000	0.920	0.080
E10.1 With ketoacidosis	0.000	0.920	0.080
E10.3 With ophthalmic complications	0.000	0.926	0.074
E66 Obesity	0.000	0.928	0.072
E10.4 With neurological complications	0.000	0.931	0.069
E65-E68 Obesity and other hyperalimentation	0.000	0.933	0.067
E13.9 Without complications	0.000	0.934	0.066
M51.4 Schmorl's nodes	0.000	0.934	0.066
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.935	0.065
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified	0.000	0.942	0.058
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region	0.000	0.942	0.058
M51.37 Other intervertebral disc degeneration, lumbosacral region	0.000	0.942	0.058
E50-E64 Other nutritional deficiencies	0.000	0.944	0.056
I07.1 Tricuspid insufficiency	0.056	0.944	0.000
E55 Vitamin D deficiency	0.000	0.945	0.055
E55.9 Vitamin D deficiency, unspecified	0.000	0.945	0.055
E66.1 Drug-induced obesity	0.000	0.948	0.051
E66.8 Other obesity	0.000	0.949	0.051
M51.9 Intervertebral disk disorder, unspecified	0.000	0.951	0.049
E67 Other hyperalimentation	0.000	0.952	0.048
E68 Sequelae of hyperalimentation	0.000	0.952	0.048
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.952	0.048
E66.0 Obesity due to excess calories	0.000	0.955	0.045
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.955	0.044
E14 Unspecified diabetes mellitus	0.000	0.956	0.044
E65 Localised adiposity	0.000	0.956	0.044
M51.2 Other specified intervertebral disk displacement	0.000	0.959	0.041
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.960	0.040
E63 Other nutritional deficiencies	0.000	0.960	0.040
E56 Other vitamin deficiencies	0.000	0.960	0.040
E50 Vitamin A deficiency	0.000	0.960	0.040
E60 Dietary zinc deficiency	0.000	0.960	0.040
E59 Dietary selenium deficiency	0.000	0.960	0.040
E58 Dietary calcium deficiency	0.000	0.960	0.040
E54 Ascorbic acid deficiency	0.000	0.960	0.040
E52 Niacin deficiency [pellagra]	0.000	0.960	0.040
E55.0 Rickets, active	0.000	0.960	0.039
E51 Thiamine deficiency	0.000	0.961	0.039
K60.2 Anal fissure, unspecified	0.000	0.961	0.039
E40-E46 Malnutrition	0.000	0.961	0.038
E83.1 Disorders of iron metabolism	0.000	0.962	0.038
K60 Fissure and fistula of anal and rectal regions	0.000	0.962	0.038
K60.1 Chronic anal fissure	0.000	0.964	0.036
E67.8 Other specified hyperalimentation	0.000	0.965	0.035
E67.3 Hypervitaminosis D	0.000	0.965	0.035
E67.2 Megavitamin-B6 syndrome	0.000	0.965	0.035
E67.1 Hypercarotenaemia	0.000	0.965	0.035
E67.0 Hypervitaminosis A	0.000	0.965	0.035
K60.4 Rectal fistula	0.000	0.966	0.034
K60.3 Anal fistula	0.000	0.967	0.033
E14.4 With neurological complications	0.000	0.968	0.032
E15 Nondiabetic hypoglycaemic coma	0.000	0.968	0.032
I07 Rheumatic tricuspid valve diseases	0.032	0.968	0.000
E14.7 With multiple complications	0.000	0.968	0.032
E14.6 With other specified complications	0.000	0.968	0.032
E14.5 With peripheral circulatory complications	0.000	0.968	0.032
E14.1 With ketoacidosis	0.000	0.968	0.032
E14.0 With coma	0.000	0.968	0.032
E53 Deficiency of other B group vitamins	0.000	0.970	0.030
E16 Other disorders of pancreatic internal secretion	0.000	0.970	0.030
E14.8 With unspecified complications	0.000	0.971	0.029
E14.2 Withrenal complications	0.000	0.971	0.029
E50.9 Vitamin A deficiency, unspecified	0.000	0.971	0.029
E50.8 Other manifestations of vitamin A deficiency	0.000	0.971	0.029
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.971	0.029
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.971	0.029
E50.5 Vitamin A deficiency with night blindness	0.000	0.971	0.029
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.971	0.029
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.971	0.029
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.971	0.029
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.971	0.029
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.971	0.029
E56.9 Vitamin deficiency, unspecified	0.000	0.971	0.029
E56.8 Deficiency of other vitamins	0.000	0.971	0.029
E56.1 Deficiency of vitamin K	0.000	0.971	0.029
E56.0 Deficiency of vitamin E	0.000	0.971	0.029
E63.9 Nutritional deficiency, unspecified	0.000	0.971	0.029
E63.8 Other specified nutritional deficiencies	0.000	0.971	0.029
E63.1 Imbalance of constituents of food intake	0.000	0.971	0.029
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.971	0.029
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.971	0.029
E64.8 Sequelae of other nutritional deficiencies	0.000	0.971	0.029
E64.3 Sequelae of rickets	0.000	0.971	0.029
E64.2 Sequelae of vitamin C deficiency	0.000	0.971	0.029
E64.1 Sequelae of vitamin A deficiency	0.000	0.971	0.029
E64.0 Sequelae of protein-energy malnutrition	0.000	0.971	0.029
K60.0 Acute anal fissure	0.000	0.971	0.029
E51.9 Thiamine deficiency, unspecified	0.000	0.972	0.028
E51.8 Other manifestations of thiamine deficiency	0.000	0.972	0.028
E51.1 Beriberi	0.000	0.972	0.028
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.972	0.028
E45 Retarded development following protein-energy malnutrition	0.000	0.972	0.028
E43 Unspecified severe protein-energy malnutrition	0.000	0.972	0.028
E42 Marasmic kwashiorkor	0.000	0.972	0.028
E41 Nutritional marasmus	0.000	0.972	0.028
E40 Kwashiorkor	0.000	0.972	0.028
E61 Deficiency of other nutrient elements	0.000	0.972	0.027
E51.2 Wernicke's encephalopathy	0.000	0.972	0.027
K60.5 Anorectal fistula	0.000	0.973	0.027
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.001	0.974	0.025
E16.1 Other hypoglycaemia	0.000	0.975	0.024
I07.9 Tricuspid valve disease, unspecified	0.023	0.977	0.000
I07.8 Other tricuspid valve diseases	0.023	0.977	0.000
I07.2 Tricuspid stenosis with insufficiency	0.023	0.977	0.000
I07.0 Tricuspid stenosis	0.023	0.977	0.000
E83 Disorders of mineral metabolism	0.000	0.977	0.023
E53.1 Pyridoxine deficiency	0.000	0.978	0.022
E53.0 Riboflavin deficiency	0.000	0.978	0.022
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.979	0.021
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.979	0.021
E16.4 Abnormal secretion of gastrin	0.000	0.979	0.021
E16.3 Increased secretion of glucagon	0.000	0.979	0.021
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.979	0.021
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.020	0.980	0.000
E44.1 Mild protein-energy malnutrition	0.000	0.980	0.020
E44.0 Moderate protein-energy malnutrition	0.000	0.980	0.020
E61.9 Deficiency of nutrient element, unspecified	0.000	0.980	0.020
E61.8 Deficiency of other specified nutrient elements	0.000	0.980	0.020
E61.7 Deficiency of multiple nutrient elements	0.000	0.980	0.020
E61.6 Vanadium deficiency	0.000	0.980	0.020
E61.5 Molybdenum deficiency	0.000	0.980	0.020
E61.4 Chromium deficiency	0.000	0.980	0.020
E61.3 Manganese deficiency	0.000	0.980	0.020
E61.0 Copper deficiency	0.000	0.980	0.020
E70-E90 Metabolic disorders	0.000	0.980	0.020
E46 Unspecified protein-energy malnutrition	0.000	0.981	0.019
Y51 Drugs primarily affecting the autonomic nervous system	0.019	0.981	0.000
E61.2 Magnesium deficiency	0.000	0.981	0.019
D04.3 Skin of other and unspecified parts of face	0.019	0.981	0.000
E83.3 Disorders of phosphorus metabolism	0.000	0.981	0.019
E53.9 Vitamin B deficiency, unspecified	0.000	0.982	0.018
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.018	0.982	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.018	0.982	0.000
E53.8 Deficiency of other specified B group vitamins	0.000	0.983	0.017
Y52 Agents primarily affecting the cardiovascular system	0.017	0.983	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.017	0.983	0.000
Y54.3 Benzothiadiazine derivatives	0.017	0.983	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.983	0.016
E83.8 Other disorders of mineral metabolism	0.000	0.983	0.016
E83.2 Disorders of zinc metabolism	0.000	0.983	0.016
E83.0 Disorders of copper metabolism	0.000	0.983	0.016
I63.9 Cerebral infarction, unspecified	0.000	0.984	0.016
Y49.2 Other and unspecified antidepressants	0.016	0.984	0.000
Y54.7 Agents affecting calcification	0.016	0.984	0.000
Y44 Agents primarily affecting blood constituents	0.016	0.984	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.016	0.984	0.000
E14.3 With ophthalmic complications	0.000	0.984	0.015
E20-E35 Disorders of other endocrine glands	0.000	0.984	0.016
Y41 Other systemic anti-infectives and antiparasitics	0.016	0.984	0.000
E73 Lactose intolerance	0.000	0.985	0.015
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.015	0.985	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.015	0.985	0.000
I05-I09 Chronic rheumatic heart diseases	0.015	0.985	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.015	0.985	0.000
E85 Amyloidosis	0.000	0.985	0.015
Y52.7 Peripheral vasodilators	0.015	0.985	0.000
E84 Cystic fibrosis	0.000	0.985	0.014
E77 Disorders of glycoprotein metabolism	0.000	0.985	0.014
E76 Disorders of glycosaminoglycan metabolism	0.000	0.985	0.014
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.985	0.014
E72 Other disorders of amino-acid metabolism	0.000	0.985	0.014
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.985	0.014
E70 Disorders of aromatic amino-acid metabolism	0.000	0.985	0.014
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.985	0.014
Y46 Antiepileptics and anti-Parkinsonism drugs	0.014	0.986	0.000
E14.9 Without complications	0.000	0.986	0.014
D04 Carcinoma in situ of skin	0.014	0.986	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.014	0.986	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.014	0.986	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.014	0.986	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.014	0.986	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.014	0.986	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.014	0.986	0.000
Y51.0 Anticholinesterase agents	0.014	0.986	0.000
E88 Other metabolic disorders	0.000	0.986	0.014
Y44.2 Anticoagulants	0.014	0.986	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.014	0.986	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.013	0.986	0.000
E74 Other disorders of carbohydrate metabolism	0.000	0.987	0.013
Y59 Other and unspecified vaccines and biological substances	0.013	0.987	0.000
Y58 Bacterial vaccines	0.013	0.987	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.013	0.987	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.013	0.987	0.000
Z95.1 Presence of aortocoronary bypass graft	0.000	0.987	0.013
Y54.5 Other diuretics	0.013	0.987	0.000
E79 Disorders of purine and pyrimidine metabolism	0.000	0.987	0.013
D04.7 Skin of lower limb, including hip	0.013	0.987	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.013	0.987	0.000
Y54.9 Mineral salts, not elsewhere classified	0.013	0.987	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.013	0.987	0.000
Y54.4 Loop [high-ceiling] diuretics	0.013	0.987	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.013	0.987	0.000
Y54.0 Mineralocorticoids	0.013	0.987	0.000
E27 Other disorders of adrenal gland	0.000	0.987	0.013
Y41.0 Sulphonamides	0.013	0.987	0.000
Y43 Primarily systemic agents	0.013	0.987	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.013	0.987	0.000
E16.2 Hypoglycaemia, unspecified	0.000	0.987	0.013
Y47 Sedatives, hypnotics and antianxiety drugs	0.012	0.987	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.012	0.987	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.012	0.987	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.012	0.987	0.000
Y49.9 Psychotropic drug, unspecified	0.012	0.988	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.012	0.988	0.000
Y49.7 Psychostimulants with abuse potential	0.012	0.988	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.012	0.988	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.012	0.988	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.012	0.988	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.012	0.988	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.012	0.988	0.000
E73.9 Lactose intolerance, unspecified	0.000	0.988	0.012
I06 Rheumatic aortic valve diseases	0.012	0.988	0.000
Y54.8 Agents affecting uric acid metabolism	0.012	0.988	0.000
Y48 Anaesthetics and therapeutic gases	0.012	0.988	0.000
E20 Hypoparathyroidism	0.000	0.988	0.012
D04.6 Skin of upper limb, including shoulder	0.012	0.988	0.000
Y44.5 Thrombolytic drugs	0.012	0.988	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.012	0.988	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.012	0.988	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.012	0.988	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.012	0.988	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.988	0.012
D04.4 Skin of scalp and neck	0.012	0.988	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.988	0.012
Y44.9 Other and unspecified agents affecting blood constituents	0.011	0.988	0.000
Y44.7 Plasma substitutes	0.011	0.988	0.000
Y44.6 Natural blood and blood products	0.011	0.988	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.011	0.988	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.011	0.988	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.011	0.988	0.000
I08 Multiple valve diseases	0.012	0.988	0.000
Y46.4 Iminostilbenes	0.011	0.988	0.000
E10.9 Without complications	0.000	0.988	0.012
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.011	0.989	0.000
Y41.5 Antiviral drugs	0.011	0.989	0.000
Y41.4 Anthelminthics	0.011	0.989	0.000
Y41.3 Other antiprotozoal drugs	0.011	0.989	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.011	0.989	0.000
Y41.1 Antimycobacterial drugs	0.011	0.989	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.989	0.011
E32 Diseases of thymus	0.000	0.989	0.011
E31 Polyglandular dysfunction	0.000	0.989	0.011
E30 Disorders of puberty, not elsewhere classified	0.000	0.989	0.011
E85.3 Secondary systemic amyloidosis	0.000	0.989	0.011
E23 Hypofunction and other disorders of pituitary gland	0.000	0.989	0.011
E73.8 Other lactose intolerance	0.000	0.989	0.011
E73.1 Secondary lactase deficiency	0.000	0.989	0.011
E73.0 Congenital lactase deficiency	0.000	0.989	0.011
E29 Testicular dysfunction	0.000	0.989	0.011
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.011	0.989	0.000
I09 Other rheumatic heart diseases	0.011	0.989	0.000
D04.1 Skin of eyelid, including canthus	0.011	0.989	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.989	0.011
Y46.2 Hydantoin derivatives	0.011	0.989	0.000
E26 Hyperaldosteronism	0.000	0.989	0.011
E85.8 Other amyloidosis	0.000	0.989	0.011
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.989	0.011
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.989	0.011
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.989	0.011
E27.1 Primary adrenocortical insufficiency	0.000	0.989	0.011
Y49.5 Other antipsychotics and neuroleptics	0.011	0.989	0.000
E22 Hyperfunction of pituitary gland	0.000	0.989	0.011
E85.4 Organ-limited amyloidosis	0.000	0.989	0.011
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.989	0.010
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.989	0.010
E70.3 Albinism	0.000	0.989	0.010
E70.2 Disorders of tyrosine metabolism	0.000	0.989	0.010
E70.1 Other hyperphenylalaninaemias	0.000	0.989	0.010
E70.0 Classical phenylketonuria	0.000	0.989	0.010
E71.3 Disorders of fatty-acid metabolism	0.000	0.989	0.010
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.989	0.010
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.989	0.010
E71.0 Maple-syrup-urine disease	0.000	0.989	0.010
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.989	0.010
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.989	0.010
E72.5 Disorders of glycine metabolism	0.000	0.989	0.010
E72.4 Disorders of ornithine metabolism	0.000	0.989	0.010
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.989	0.010
E72.2 Disorders of urea cycle metabolism	0.000	0.989	0.010
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.989	0.010
E72.0 Disorders of amino-acid transport	0.000	0.989	0.010

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations