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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs438999
log Bayes Factor = 25.9671
Chromosome 6   position 31,928,306  (GRCh37) Explore rs438999 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.003 0.997
E10.3 With ophthalmic complications
0.000 0.008 0.992
E11 Non-insulin-dependent diabetes mellitus
0.000 0.020 0.980
E05.9 Thyrotoxicosis, unspecified
0.000 0.028 0.972
E11.3 With ophthalmic complications
0.000 0.045 0.955
E10.1 With ketoacidosis
0.000 0.047 0.953
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.059 0.941
E65-E68 Obesity and other hyperalimentation
0.000 0.059 0.941
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.068 0.932
E66 Obesity
0.000 0.103 0.897
E66.8 Other obesity
0.000 0.110 0.890
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.116 0.884
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.134 0.866
E10.5 With peripheral circulatory complications
0.000 0.134 0.866
E11.9 Without complications
0.000 0.144 0.856
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.150 0.850
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.159 0.841
E11.5 With peripheral circulatory complications
0.000 0.184 0.816
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.192 0.808
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.199 0.801
M06 Other rheumatoid arthritis
0.000 0.218 0.782
E10.4 With neurological complications
0.000 0.221 0.779
E06 Thyroiditis
0.000 0.227 0.773
E10.2 With renal complications
0.000 0.233 0.767
E11.2 With renal complications
0.000 0.237 0.763
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.259 0.741
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E05.8 Other thyrotoxicosis
0.000 0.285 0.715
E05.5 Thyroid crisis or storm
0.000 0.285 0.715
E05.4 Thyrotoxicosis factitia
0.000 0.285 0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.285 0.715
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.285 0.715
M06.0 Seronegative rheumatoid arthritis
0.000 0.296 0.704
E11.7 With multiple complications
0.000 0.297 0.703
E13 Other specified diabetes mellitus
0.000 0.297 0.703
E11.0 With coma
0.000 0.299 0.701
E65 Localised adiposity
0.000 0.306 0.693
E11.6 With other specified complications
0.000 0.318 0.682
E50-E64 Other nutritional deficiencies
0.000 0.319 0.681
E67 Other hyperalimentation
0.000 0.325 0.675
E68 Sequelae of hyperalimentation
0.000 0.325 0.675
E10.8 With unspecified complications
0.000 0.333 0.667
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.349 0.650
E66.1 Drug-induced obesity
0.000 0.357 0.643
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.369 0.630
E11.8 With unspecified complications
0.000 0.379 0.621
E06.3 Autoimmune thyroiditis
0.000 0.382 0.618
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.383 0.617
E40-E46 Malnutrition
0.000 0.385 0.615
E11.1 With ketoacidosis
0.000 0.385 0.615
E14 Unspecified diabetes mellitus
0.000 0.391 0.609
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.392 0.608
E66.0 Obesity due to excess calories
0.000 0.395 0.605
M06.3 Rheumatoid nodule
0.000 0.401 0.598
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.411 0.588
E11.4 With neurological complications
0.000 0.418 0.582
M06.8 Other specified rheumatoid arthritis
0.000 0.439 0.560
M06.2 Rheumatoid bursitis
0.000 0.439 0.560
M06.1 Adult-onset Still's disease
0.000 0.439 0.560
E06.5 Other chronic thyroiditis
0.000 0.446 0.554
E06.4 Drug-induced thyroiditis
0.000 0.446 0.554
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.446 0.554
E06.1 Subacute thyroiditis
0.000 0.446 0.554
E06.0 Acute thyroiditis
0.000 0.446 0.554
E06.9 Thyroiditis, unspecified
0.000 0.456 0.544
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.495 0.505
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.495 0.505
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.495 0.505
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.495 0.505
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.495 0.505
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.495 0.505
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.495 0.505
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.495 0.505
E13.8 With unspecified complications
0.000 0.496 0.504
E13.7 With multiple complications
0.000 0.496 0.504
E13.6 With other specified complications
0.000 0.496 0.504
E13.5 With peripheral circulatory complications
0.000 0.496 0.504
E13.4 With neurological complications
0.000 0.496 0.504
E13.3 With ophthalmic complications
0.000 0.496 0.504
E13.2 With renal complications
0.000 0.496 0.504
E13.1 With ketoacidosis
0.000 0.496 0.504
E13.0 With coma
0.000 0.496 0.504
M06.4 Inflammatory polyarthropathy
0.000 0.498 0.502
E13.9 Without complications
0.000 0.510 0.490
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.511 0.489
E63 Other nutritional deficiencies
0.000 0.511 0.489
E56 Other vitamin deficiencies
0.000 0.511 0.489
E51 Thiamine deficiency
0.000 0.511 0.489
E50 Vitamin A deficiency
0.000 0.511 0.489
E60 Dietary zinc deficiency
0.000 0.511 0.489
E59 Dietary selenium deficiency
0.000 0.511 0.489
E58 Dietary calcium deficiency
0.000 0.511 0.489
E54 Ascorbic acid deficiency
0.000 0.511 0.489
E52 Niacin deficiency [pellagra]
0.000 0.511 0.489
E03.8 Other specified hypothyroidism
0.001 0.512 0.488
E67.8 Other specified hyperalimentation
0.000 0.516 0.484
E67.3 Hypervitaminosis D
0.000 0.516 0.484
E67.2 Megavitamin-B6 syndrome
0.000 0.516 0.484
E67.1 Hypercarotenaemia
0.000 0.516 0.484
E67.0 Hypervitaminosis A
0.000 0.516 0.484
E61 Deficiency of other nutrient elements
0.000 0.520 0.479
E53 Deficiency of other B group vitamins
0.000 0.523 0.477
E55 Vitamin D deficiency
0.000 0.523 0.477
E07 Other disorders of thyroid
0.000 0.530 0.469
M06.34 Rheumatoid nodule (Hand)
0.000 0.533 0.467
E15 Nondiabetic hypoglycaemic coma
0.000 0.533 0.466
E20-E35 Disorders of other endocrine glands
0.000 0.540 0.460
E14.3 With ophthalmic complications
0.000 0.550 0.450
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.559 0.441
E45 Retarded development following protein-energy malnutrition
0.000 0.559 0.441
E43 Unspecified severe protein-energy malnutrition
0.000 0.559 0.441
E42 Marasmic kwashiorkor
0.000 0.559 0.441
E41 Nutritional marasmus
0.000 0.559 0.441
E40 Kwashiorkor
0.000 0.559 0.441
E14.8 With unspecified complications
0.000 0.563 0.436
E14.7 With multiple complications
0.000 0.563 0.436
E14.6 With other specified complications
0.000 0.563 0.436
E14.5 With peripheral circulatory complications
0.000 0.563 0.436
E14.4 With neurological complications
0.000 0.563 0.436
E14.1 With ketoacidosis
0.000 0.563 0.436
E14.0 With coma
0.000 0.563 0.436
E04 Other non-toxic goitre
0.000 0.564 0.436
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.571 0.429
M06.38 Rheumatoid nodule (Other)
0.000 0.571 0.429
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.571 0.429
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.571 0.429
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.571 0.429
M06.33 Rheumatoid nodule (Forearm)
0.000 0.571 0.429
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.571 0.429
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.571 0.429
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.571 0.429
E27 Other disorders of adrenal gland
0.000 0.578 0.422
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.598 0.402
M06.18 Adult-onset Still's disease (Other)
0.000 0.598 0.402
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.598 0.402
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.598 0.402
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.598 0.402
M06.14 Adult-onset Still's disease (Hand)
0.000 0.598 0.402
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.598 0.402
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.598 0.402
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.598 0.402
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.598 0.402
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.598 0.402
M06.28 Rheumatoid bursitis (Other)
0.000 0.598 0.402
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.598 0.402
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.598 0.402
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.598 0.402
M06.24 Rheumatoid bursitis (Hand)
0.000 0.598 0.402
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.598 0.402
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.598 0.402
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.598 0.402
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.598 0.402
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.598 0.402
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.598 0.402
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.598 0.402
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.598 0.402
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.598 0.402
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.598 0.402
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.598 0.402
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.598 0.402
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.598 0.402
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.598 0.402
E16 Other disorders of pancreatic internal secretion
0.000 0.599 0.401
E14.9 Without complications
0.000 0.603 0.397
E27.1 Primary adrenocortical insufficiency
0.000 0.629 0.371
E14.2 Withrenal complications
0.000 0.639 0.361
E20 Hypoparathyroidism
0.000 0.639 0.361
M05-M14 Inflammatory polyarthropathies
0.003 0.640 0.357
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.640 0.360
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.640 0.360
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.640 0.360
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.640 0.360
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.640 0.360
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.640 0.360
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.640 0.360
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.640 0.360
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.640 0.360
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.641 0.359
E27.8 Other specified disorders of adrenal gland
0.000 0.645 0.355
E50.9 Vitamin A deficiency, unspecified
0.000 0.649 0.350
E50.8 Other manifestations of vitamin A deficiency
0.000 0.649 0.350
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.649 0.350
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.649 0.350
E50.5 Vitamin A deficiency with night blindness
0.000 0.649 0.350
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.649 0.350
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.649 0.350
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.649 0.350
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.649 0.350
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.649 0.350
E51.9 Thiamine deficiency, unspecified
0.000 0.649 0.350
E51.8 Other manifestations of thiamine deficiency
0.000 0.649 0.350
E51.2 Wernicke's encephalopathy
0.000 0.649 0.350
E51.1 Beriberi
0.000 0.649 0.350
E56.9 Vitamin deficiency, unspecified
0.000 0.649 0.350
E56.8 Deficiency of other vitamins
0.000 0.649 0.350
E56.1 Deficiency of vitamin K
0.000 0.649 0.350
E56.0 Deficiency of vitamin E
0.000 0.649 0.350
E63.9 Nutritional deficiency, unspecified
0.000 0.649 0.350
E63.8 Other specified nutritional deficiencies
0.000 0.649 0.350
E63.1 Imbalance of constituents of food intake
0.000 0.649 0.350
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.649 0.350
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.649 0.350
E64.8 Sequelae of other nutritional deficiencies
0.000 0.649 0.350
E64.3 Sequelae of rickets
0.000 0.649 0.350
E64.2 Sequelae of vitamin C deficiency
0.000 0.649 0.350
E64.1 Sequelae of vitamin A deficiency
0.000 0.649 0.350
E64.0 Sequelae of protein-energy malnutrition
0.000 0.649 0.350
E53.8 Deficiency of other specified B group vitamins
0.000 0.651 0.349
E04.0 Non-toxic diffuse goitre
0.000 0.655 0.345
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.655 0.345
E61.9 Deficiency of nutrient element, unspecified
0.000 0.656 0.344
E61.8 Deficiency of other specified nutrient elements
0.000 0.656 0.344
E61.7 Deficiency of multiple nutrient elements
0.000 0.656 0.344
E61.6 Vanadium deficiency
0.000 0.656 0.344
E61.5 Molybdenum deficiency
0.000 0.656 0.344
E61.4 Chromium deficiency
0.000 0.656 0.344
E61.3 Manganese deficiency
0.000 0.656 0.344
E61.2 Magnesium deficiency
0.000 0.656 0.344
E61.0 Copper deficiency
0.000 0.656 0.344
E53.1 Pyridoxine deficiency
0.000 0.658 0.342
E53.0 Riboflavin deficiency
0.000 0.658 0.342
E55.0 Rickets, active
0.000 0.658 0.342
E46 Unspecified protein-energy malnutrition
0.000 0.661 0.339
E07.1 Dyshormogenetic goitre
0.000 0.663 0.337
E07.0 Hypersecretion of calcitonin
0.000 0.663 0.337
E61.1 Iron deficiency
0.000 0.665 0.335
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.670 0.330
E32 Diseases of thymus
0.000 0.670 0.330
E31 Polyglandular dysfunction
0.000 0.670 0.330
E30 Disorders of puberty, not elsewhere classified
0.000 0.670 0.330
E55.9 Vitamin D deficiency, unspecified
0.000 0.670 0.330
E04.2 Non-toxic multinodular goitre
0.000 0.673 0.327
E53.9 Vitamin B deficiency, unspecified
0.000 0.678 0.322
E27.2 Addisonian crisis
0.000 0.681 0.319
E22 Hyperfunction of pituitary gland
0.000 0.681 0.318
M05 Seropositive rheumatoid arthritis
0.002 0.683 0.315
E44.1 Mild protein-energy malnutrition
0.000 0.684 0.316
E44.0 Moderate protein-energy malnutrition
0.000 0.684 0.316
E04.8 Other specified non-toxic goitre
0.000 0.687 0.313
L40.9 Psoriasis, unspecified
0.000 0.688 0.312
L40 Psoriasis
0.000 0.688 0.312
L40.5 Arthropathic psoriasis
0.000 0.688 0.312
E07.8 Other specified disorders of thyroid
0.001 0.694 0.306
M07 Psoriatic and enteropathic arthropathies
0.002 0.696 0.302
E27.5 Adrenomedullary hyperfunction
0.000 0.697 0.302
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.697 0.302
E27.0 Other adrenocortical overactivity
0.000 0.697 0.302
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.001 0.699 0.301
E28 Ovarian dysfunction
0.000 0.702 0.298
E21.3 Hyperparathyroidism, unspecified
0.000 0.705 0.295
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.710 0.290
E20.9 Hypoparathyroidism, unspecified
0.000 0.710 0.290
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.713 0.287
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.713 0.287
E16.4 Abnormal secretion of gastrin
0.000 0.713 0.287
E16.3 Increased secretion of glucagon
0.000 0.713 0.287
E26 Hyperaldosteronism
0.000 0.713 0.286
M05.9 Seropositive rheumatoid arthritis, unspecified
0.001 0.714 0.285
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.718 0.282
E24 Cushing's syndrome
0.000 0.730 0.269
E16.1 Other hypoglycaemia
0.000 0.734 0.266
E25 Adrenogenital disorders
0.001 0.736 0.263
M07.3 Other psoriatic arthropathies
0.001 0.737 0.263
L40.0 Psoriasis vulgaris
0.000 0.738 0.262
E29 Testicular dysfunction
0.000 0.738 0.261
E20.8 Other hypoparathyroidism
0.000 0.741 0.259
E20.1 Pseudohypoparathyroidism
0.000 0.741 0.259
E20.0 Idiopathic hypoparathyroidism
0.000 0.741 0.259
M12 Other specific arthropathies
0.002 0.741 0.256
M09 Juvenile arthritis in diseases classified elsewhere
0.002 0.741 0.256
M08 Juvenile arthritis
0.002 0.741 0.256
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.743 0.257
E21.4 Other specified disorders of parathyroid gland
0.000 0.743 0.257
E21.2 Other hyperparathyroidism
0.000 0.743 0.257
M14 Arthropathies in other diseases classified elsewhere
0.002 0.746 0.252
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.746 0.254
E22.1 Hyperprolactinaemia
0.000 0.751 0.249
E23 Hypofunction and other disorders of pituitary gland
0.000 0.752 0.248
E16.2 Hypoglycaemia, unspecified
0.000 0.754 0.246
M11 Other crystal arthropathies
0.002 0.761 0.236
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.762 0.238
E30.9 Disorder of puberty, unspecified
0.000 0.763 0.236
E30.8 Other disorders of puberty
0.000 0.763 0.236
E30.1 Precocious puberty
0.000 0.763 0.236
E30.0 Delayed puberty
0.000 0.763 0.236
E31.9 Polyglandular dysfunction, unspecified
0.000 0.763 0.236
E31.8 Other polyglandular dysfunction
0.000 0.763 0.236
E31.1 Polyglandular hyperfunction
0.000 0.763 0.236
E31.0 Autoimmune polyglandular failure
0.000 0.763 0.236
E32.9 Disease of thymus, unspecified
0.000 0.763 0.236
E32.8 Other diseases of thymus
0.000 0.763 0.236
E32.1 Abscess of thymus
0.000 0.763 0.236
E32.0 Persistent hyperplasia of thymus
0.000 0.763 0.236
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.763 0.236
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.763 0.236
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.763 0.236
E34 Other endocrine disorders
0.000 0.764 0.235
L40.8 Other psoriasis
0.000 0.770 0.230
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.771 0.228
E22.8 Other hyperfunction of pituitary gland
0.000 0.771 0.228
M05.8 Other seropositive rheumatoid arthritis
0.001 0.772 0.226
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.001 0.772 0.226
M05.2 Rheumatoid vasculitis
0.001 0.772 0.226
M05.1 Rheumatoid lung disease
0.001 0.772 0.226
M05.0 Felty's syndrome
0.001 0.772 0.226
L40.4 Guttate psoriasis
0.000 0.776 0.224
L40.3 Pustulosis palmaris et plantaris
0.000 0.776 0.224
L40.2 Acrodermatitis continua
0.000 0.776 0.224
L40.1 Generalised pustular psoriasis
0.000 0.776 0.224
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.780 0.220
M07.6 Other enteropathic arthropathies
0.001 0.782 0.217
M07.5 Arthropathy in ulcerative colitis
0.001 0.782 0.217
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.001 0.782 0.217
M07.2 Psoriatic spondylitis
0.001 0.782 0.217
M07.1 Arthritis mutilans
0.001 0.782 0.217
M07.0 Distal interphalangeal psoriatic arthropathy
0.001 0.782 0.217
E27.9 Disorder of adrenal gland, unspecified
0.000 0.785 0.214
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.786 0.213
E28.9 Ovarian dysfunction, unspecified
0.000 0.786 0.213
E28.8 Other ovarian dysfunction
0.000 0.786 0.213
E28.3 Primary ovarian failure
0.000 0.786 0.213
E28.1 Androgen excess
0.000 0.786 0.213
E28.0 Oestrogen excess
0.000 0.786 0.213
E22.0 Acromegaly and pituitary gigantism
0.000 0.789 0.211
S61.0 Open wound of finger(s) without damage to nail
0.209 0.791 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.791 0.208
E26.9 Hyperaldosteronism, unspecified
0.000 0.794 0.205
E26.8 Other hyperaldosteronism
0.000 0.794 0.205
E26.1 Secondary hyperaldosteronism
0.000 0.794 0.205
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.001 0.795 0.205
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.001 0.795 0.205
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.001 0.795 0.205
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.001 0.795 0.205
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.001 0.795 0.205
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.001 0.795 0.205
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.001 0.795 0.205
E21.0 Primary hyperparathyroidism
0.000 0.795 0.205
M10 Gout
0.002 0.806 0.192
E24.8 Other Cushing's syndrome
0.000 0.807 0.193
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.807 0.193
E24.3 Ectopic ACTH syndrome
0.000 0.807 0.193
E24.2 Drug-induced Cushing's syndrome
0.000 0.807 0.193
E24.1 Nelson's syndrome
0.000 0.807 0.193
E24.0 Pituitary-dependent Cushing's disease
0.000 0.807 0.193
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.001 0.807 0.193
L40-L45 Papulosquamous disorders
0.000 0.809 0.191
E25.9 Adrenogenital disorder, unspecified
0.001 0.811 0.189
E25.8 Other adrenogenital disorders
0.001 0.811 0.189
M07.38 Other psoriatic arthropathies (Other)
0.001 0.811 0.188
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.001 0.811 0.188
M07.36 Other psoriatic arthropathies (Lower leg)
0.001 0.811 0.188
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.001 0.811 0.188
M07.34 Other psoriatic arthropathies (Hand)
0.001 0.811 0.188
M07.33 Other psoriatic arthropathies (Forearm)
0.001 0.811 0.188
M07.32 Other psoriatic arthropathies (Upper arm)
0.001 0.811 0.188
M07.31 Other psoriatic arthropathies (Shoulder region)
0.001 0.811 0.188
E29.9 Testicular dysfunction, unspecified
0.000 0.812 0.187
E29.8 Other testicular dysfunction
0.000 0.812 0.187
E29.0 Testicular hyperfunction
0.000 0.812 0.187
E04.1 Non-toxic single thyroid nodule
0.000 0.813 0.187
M08.9 Juvenile arthritis, unspecified
0.002 0.814 0.184
M08.8 Other juvenile arthritis
0.002 0.814 0.184
M08.4 Pauciarticular juvenile arthritis
0.002 0.814 0.184
M08.3 Juvenile polyarthritis (seronegative)
0.002 0.814 0.184
M08.2 Juvenile arthritis with systemic onset
0.002 0.814 0.184
M08.1 Juvenile ankylosing spondylitis
0.002 0.814 0.184
M08.0 Juvenile rheumatoid arthritis
0.002 0.814 0.184
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.002 0.814 0.184
M09.2 Juvenile arthritis in ulcerative colitis
0.002 0.814 0.184
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.002 0.814 0.184
M09.0 Juvenile arthritis in psoriasis
0.002 0.814 0.184
M12.8 Other specific arthropathies, not elsewhere classified
0.002 0.814 0.184
M12.5 Traumatic arthropathy
0.002 0.814 0.184
M12.4 Intermittent hydrarthrosis
0.002 0.814 0.184
M12.3 Palindromic rheumatism
0.002 0.814 0.184
M12.2 Villonodular synovitis (pigmented)
0.002 0.814 0.184
M12.1 Kaschin-Beck disease
0.002 0.814 0.184
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.002 0.814 0.184
M14.8 Arthropathies in other specified diseases classified elsewhere
0.002 0.818 0.181
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.002 0.818 0.181
M14.4 Arthropathy in amyloidosis
0.002 0.818 0.181
M14.3 Lipoid dermatoarthritis
0.002 0.818 0.181
M14.2 Diabetic arthropathy
0.002 0.818 0.181
M14.1 Crystal arthropathy in other metabolic disorders
0.002 0.818 0.181
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.002 0.818 0.181
E28.2 Polycystic ovarian syndrome
0.000 0.818 0.181
E23.7 Disorder of pituitary gland, unspecified
0.000 0.821 0.179
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.822 0.178
E23.1 Drug-induced hypopituitarism
0.000 0.822 0.178
M14.6 Neuropathic arthropathy
0.002 0.822 0.176
E23.2 Diabetes insipidus
0.000 0.827 0.172
M11.9 Crystal arthropathy, unspecified
0.002 0.829 0.170
M11.8 Other specified crystal arthropathies
0.002 0.829 0.170
M11.1 Familial chondrocalcinosis
0.002 0.829 0.170
M11.0 Hydroxyapatite deposition disease
0.002 0.829 0.170
E34.5 Androgen resistance syndrome
0.000 0.831 0.169
E34.4 Constitutional tall stature
0.000 0.831 0.169
E34.3 Short stature, not elsewhere classified
0.000 0.831 0.169
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.831 0.169
E34.1 Other hypersecretion of intestinal hormones
0.000 0.831 0.169
M05.09 Felty's syndrome (Site unspecified)
0.001 0.837 0.162
M05.08 Felty's syndrome (Other)
0.001 0.837 0.162
M05.07 Felty's syndrome (Ankle and foot)
0.001 0.837 0.162
M05.06 Felty's syndrome (Lower leg)
0.001 0.837 0.162
M05.05 Felty's syndrome (Pelvic region and thigh)
0.001 0.837 0.162
M05.04 Felty's syndrome (Hand)
0.001 0.837 0.162
M05.03 Felty's syndrome (Forearm)
0.001 0.837 0.162
M05.02 Felty's syndrome (Upper arm)
0.001 0.837 0.162
M05.01 Felty's syndrome (Shoulder region)
0.001 0.837 0.162
M05.00 Felty's syndrome (Multiple sites)
0.001 0.837 0.162
M05.19 Rheumatoid lung disease (Site unspecified)
0.001 0.837 0.162
M05.18 Rheumatoid lung disease (Other)
0.001 0.837 0.162
M05.17 Rheumatoid lung disease (Ankle and foot)
0.001 0.837 0.162
M05.16 Rheumatoid lung disease (Lower leg)
0.001 0.837 0.162
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.001 0.837 0.162
M05.14 Rheumatoid lung disease (Hand)
0.001 0.837 0.162
M05.13 Rheumatoid lung disease (Forearm)
0.001 0.837 0.162
M05.12 Rheumatoid lung disease (Upper arm)
0.001 0.837 0.162
M05.11 Rheumatoid lung disease (Shoulder region)
0.001 0.837 0.162
M05.10 Rheumatoid lung disease (Multiple sites)
0.001 0.837 0.162
M05.29 Rheumatoid vasculitis (Site unspecified)
0.001 0.837 0.162
M05.28 Rheumatoid vasculitis (Other)
0.001 0.837 0.162
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.001 0.837 0.162
M05.26 Rheumatoid vasculitis (Lower leg)
0.001 0.837 0.162
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.001 0.837 0.162
M05.24 Rheumatoid vasculitis (Hand)
0.001 0.837 0.162
M05.23 Rheumatoid vasculitis (Forearm)
0.001 0.837 0.162
M05.22 Rheumatoid vasculitis (Upper arm)
0.001 0.837 0.162
M05.21 Rheumatoid vasculitis (Shoulder region)
0.001 0.837 0.162
M05.20 Rheumatoid vasculitis (Multiple sites)
0.001 0.837 0.162
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.001 0.837 0.162
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.001 0.837 0.162
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.001 0.837 0.162
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.001 0.837 0.162
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.001 0.837 0.162
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.001 0.837 0.162
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.001 0.837 0.162
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.001 0.837 0.162
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.001 0.837 0.162
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.001 0.837 0.162
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.001 0.837 0.162
M05.88 Other seropositive rheumatoid arthritis (Other)
0.001 0.837 0.162
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.001 0.837 0.162
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.001 0.837 0.162
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.001 0.837 0.162
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.001 0.837 0.162
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.001 0.837 0.162
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.001 0.837 0.162
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.001 0.837 0.162
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.001 0.837 0.162
M13 Other arthritis
0.001 0.837 0.162
E26.0 Primary hyperaldosteronism
0.001 0.837 0.162
E07.9 Disorder of thyroid, unspecified
0.001 0.839 0.160
S61 Open wound of wrist and hand
0.157 0.843 0.000
E23.6 Other disorders of pituitary gland
0.000 0.843 0.156
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.001 0.843 0.155
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.001 0.843 0.155
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.001 0.843 0.155
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.001 0.843 0.155
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.001 0.843 0.155

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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