TreeWAS
Search
Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
About
Frequently Asked Questions
Citation
Download association data
for this variant in csv format
Share this page

Variant-specific associations

rs4412193
log Bayes Factor = 46.3174
Chromosome 6   position 26,338,056  (GRCh37) Explore rs4412193 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?
Associations at terminal nodes are shown if p(effect) ≥
Click here to show this figure without filtering.
Click on a node to zoom (except terminal nodes).
Download this figure in format
Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.116 0.884
E10-E14 Diabetes mellitus
0.000 0.131 0.869
E11.2 With renal complications
0.000 0.138 0.862
E10 Insulin-dependent diabetes mellitus
0.000 0.143 0.857
E11.9 Without complications
0.000 0.147 0.853
E11.5 With peripheral circulatory complications
0.000 0.165 0.835
I10 Essential (primary) hypertension
0.000 0.205 0.795
E10.0 With coma
0.000 0.214 0.786
E10.5 With peripheral circulatory complications
0.000 0.221 0.779
E11.4 With neurological complications
0.000 0.256 0.744
E10.1 With ketoacidosis
0.000 0.260 0.740
E83 Disorders of mineral metabolism
0.000 0.269 0.731
E10.3 With ophthalmic complications
0.000 0.272 0.728
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.277 0.723
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.291 0.709
E16 Other disorders of pancreatic internal secretion
0.000 0.301 0.699
E11.3 With ophthalmic complications
0.000 0.303 0.697
E70-E90 Metabolic disorders
0.000 0.306 0.694
E16.2 Hypoglycaemia, unspecified
0.000 0.307 0.693
E11.6 With other specified complications
0.000 0.335 0.664
E10.8 With unspecified complications
0.000 0.343 0.657
E11.1 With ketoacidosis
0.000 0.346 0.654
E40-E46 Malnutrition
0.000 0.351 0.649
E10.2 With renal complications
0.000 0.354 0.646
E11.0 With coma
0.000 0.362 0.638
E11.7 With multiple complications
0.000 0.366 0.633
E12 Malnutrition-related diabetes mellitus
0.000 0.377 0.623
E10.7 With multiple complications
0.000 0.386 0.614
E46 Unspecified protein-energy malnutrition
0.000 0.404 0.596
E14 Unspecified diabetes mellitus
0.000 0.419 0.581
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.425 0.575
E13 Other specified diabetes mellitus
0.000 0.426 0.573
E10.4 With neurological complications
0.000 0.437 0.563
E88 Other metabolic disorders
0.000 0.445 0.555
E10.6 With other specified complications
0.000 0.452 0.548
E73 Lactose intolerance
0.000 0.458 0.542
E84 Cystic fibrosis
0.000 0.459 0.541
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.476 0.524
E83.8 Other disorders of mineral metabolism
0.000 0.476 0.524
E83.2 Disorders of zinc metabolism
0.000 0.476 0.524
E83.0 Disorders of copper metabolism
0.000 0.476 0.524
E79 Disorders of purine and pyrimidine metabolism
0.000 0.487 0.513
E14.3 With ophthalmic complications
0.000 0.487 0.513
E10.9 Without complications
0.000 0.491 0.509
E15 Nondiabetic hypoglycaemic coma
0.000 0.492 0.508
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.498 0.502
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.499 0.501
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.499 0.501
E16.4 Abnormal secretion of gastrin
0.000 0.499 0.501
E16.3 Increased secretion of glucagon
0.000 0.499 0.501
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.502 0.498
E76 Disorders of glycosaminoglycan metabolism
0.000 0.502 0.497
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.502 0.497
E70 Disorders of aromatic amino-acid metabolism
0.000 0.502 0.497
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.502 0.497
E80.4 Gilbert's syndrome
0.000 0.505 0.495
E11.8 With unspecified complications
0.000 0.508 0.491
E16.1 Other hypoglycaemia
0.000 0.511 0.489
E77 Disorders of glycoprotein metabolism
0.000 0.528 0.472
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.535 0.465
E45 Retarded development following protein-energy malnutrition
0.000 0.535 0.465
E43 Unspecified severe protein-energy malnutrition
0.000 0.535 0.465
E42 Marasmic kwashiorkor
0.000 0.535 0.465
E41 Nutritional marasmus
0.000 0.535 0.465
E40 Kwashiorkor
0.000 0.535 0.465
E14.6 With other specified complications
0.000 0.536 0.464
E88.8 Other specified metabolic disorders
0.000 0.543 0.457
E83.3 Disorders of phosphorus metabolism
0.000 0.551 0.449
E12.9 Without complications
0.000 0.553 0.447
E12.8 With unspecified complications
0.000 0.553 0.447
E12.7 With multiple complications
0.000 0.553 0.447
E12.6 With other specified complications
0.000 0.553 0.447
E12.5 With peripheral circulatory complications
0.000 0.553 0.447
E12.4 With neurological complications
0.000 0.553 0.447
E12.3 With ophthalmic complications
0.000 0.553 0.447
E12.2 With renal complications
0.000 0.553 0.447
E12.1 With ketoacidosis
0.000 0.553 0.447
E12.0 With coma
0.000 0.553 0.447
E14.5 With peripheral circulatory complications
0.000 0.560 0.440
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.562 0.438
E72 Other disorders of amino-acid metabolism
0.000 0.562 0.437
E80.2 Other porphyria
0.000 0.566 0.434
E73.9 Lactose intolerance, unspecified
0.000 0.566 0.434
E84.9 Cystic fibrosis, unspecified
0.000 0.568 0.432
E74 Other disorders of carbohydrate metabolism
0.000 0.574 0.426
E14.1 With ketoacidosis
0.000 0.576 0.424
E14.7 With multiple complications
0.000 0.583 0.417
E14.0 With coma
0.000 0.583 0.417
E13.3 With ophthalmic complications
0.000 0.584 0.415
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.588 0.412
E80.5 Crigler-Najjar syndrome
0.000 0.588 0.412
E80.3 Defects of catalase and peroxydase
0.000 0.588 0.412
E80.1 Porphyria cutanea tarda
0.000 0.588 0.412
E80.0 Hereditary erythropoietic porphyria
0.000 0.588 0.412
E83.4 Disorders of magnesium metabolism
0.000 0.588 0.412
E13.8 With unspecified complications
0.000 0.589 0.411
E13.7 With multiple complications
0.000 0.589 0.411
E13.6 With other specified complications
0.000 0.589 0.411
E13.5 With peripheral circulatory complications
0.000 0.589 0.411
E13.4 With neurological complications
0.000 0.589 0.411
E13.2 With renal complications
0.000 0.589 0.411
E13.1 With ketoacidosis
0.000 0.589 0.411
E13.0 With coma
0.000 0.589 0.411
E14.8 With unspecified complications
0.000 0.591 0.408
E88.3 Tumour lysis syndrome
0.000 0.601 0.399
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.604 0.396
E88.9 Metabolic disorder, unspecified
0.000 0.607 0.393
E14.4 With neurological complications
0.000 0.608 0.392
E65-E68 Obesity and other hyperalimentation
0.000 0.610 0.390
E73.8 Other lactose intolerance
0.000 0.611 0.389
E73.1 Secondary lactase deficiency
0.000 0.611 0.389
E73.0 Congenital lactase deficiency
0.000 0.611 0.389
E84.8 Cystic fibrosis with other manifestations
0.000 0.612 0.388
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.612 0.388
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.612 0.388
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.616 0.384
E80.6 Other disorders of bilirubin metabolism
0.000 0.626 0.374
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.632 0.368
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.632 0.368
E79.1 Lesch-Nyhan syndrome
0.000 0.632 0.368
E75.5 Other lipid storage disorders
0.000 0.636 0.364
E75.6 Lipid storage disorder, unspecified
0.000 0.640 0.360
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.640 0.360
E75.3 Sphingolipidosis, unspecified
0.000 0.640 0.360
E75.2 Other sphingolipidosis
0.000 0.640 0.360
E75.1 Other gangliosidosis
0.000 0.640 0.360
E75.0 GM2 gangliosidosis
0.000 0.640 0.360
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.643 0.357
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.643 0.357
E70.3 Albinism
0.000 0.643 0.357
E70.2 Disorders of tyrosine metabolism
0.000 0.643 0.357
E70.1 Other hyperphenylalaninaemias
0.000 0.643 0.357
E70.0 Classical phenylketonuria
0.000 0.643 0.357
E71.3 Disorders of fatty-acid metabolism
0.000 0.643 0.357
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.643 0.357
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.643 0.357
E71.0 Maple-syrup-urine disease
0.000 0.643 0.357
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.643 0.357
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.643 0.357
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.643 0.357
E76.2 Other mucopolysaccharidoses
0.000 0.643 0.357
E76.1 Mucopolysaccharidosis, type II
0.000 0.643 0.357
E76.0 Mucopolysaccharidosis, type I
0.000 0.643 0.357
E13.9 Without complications
0.000 0.644 0.356
E88.2 Lipomatosis, not elsewhere classified
0.000 0.646 0.354
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.661 0.339
E77.1 Defects in glycoprotein degradation
0.000 0.661 0.339
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.661 0.339
E44.1 Mild protein-energy malnutrition
0.000 0.666 0.334
E44.0 Moderate protein-energy malnutrition
0.000 0.666 0.334
E14.2 Withrenal complications
0.000 0.671 0.328
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.686 0.314
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.686 0.314
E72.5 Disorders of glycine metabolism
0.000 0.686 0.314
E72.4 Disorders of ornithine metabolism
0.000 0.686 0.314
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.686 0.314
E72.2 Disorders of urea cycle metabolism
0.000 0.686 0.314
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.686 0.314
E77.8 Other disorders of glycoprotein metabolism
0.000 0.686 0.313
E65 Localised adiposity
0.000 0.689 0.311
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.694 0.305
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.694 0.305
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.694 0.305
E74.2 Disorders of galactose metabolism
0.000 0.694 0.305
E74.1 Disorders of fructose metabolism
0.000 0.694 0.305
E74.0 Glycogen storage disease
0.000 0.705 0.295
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.718 0.282
E67 Other hyperalimentation
0.000 0.720 0.280
E68 Sequelae of hyperalimentation
0.000 0.720 0.280
K90 Intestinal malabsorption
0.000 0.735 0.265
E85 Amyloidosis
0.001 0.743 0.256
E72.0 Disorders of amino-acid transport
0.001 0.746 0.254
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.751 0.249
E89.4 Postprocedural ovarian failure
0.000 0.763 0.237
E83.5 Disorders of calcium metabolism
0.000 0.775 0.225
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.782 0.218
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.785 0.215
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.797 0.202
E89.5 Postprocedural testicular hypofunction
0.000 0.797 0.202
E89.1 Postprocedural hypoinsulinaemia
0.000 0.797 0.202
E67.8 Other specified hyperalimentation
0.000 0.799 0.201
E67.3 Hypervitaminosis D
0.000 0.799 0.201
E67.2 Megavitamin-B6 syndrome
0.000 0.799 0.201
E67.1 Hypercarotenaemia
0.000 0.799 0.201
E67.0 Hypervitaminosis A
0.000 0.799 0.201
K90.3 Pancreatic steatorrhoea
0.000 0.809 0.190
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.809 0.190
K90.1 Tropical sprue
0.000 0.809 0.190
E85.8 Other amyloidosis
0.001 0.810 0.190
E50-E64 Other nutritional deficiencies
0.001 0.812 0.188
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.812 0.188
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.816 0.184
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.816 0.184
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.816 0.184
E00-E07 Disorders of thyroid gland
0.000 0.829 0.171
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.833 0.166
K90.8 Other intestinal malabsorption
0.000 0.837 0.163
E89.2 Postprocedural hypoparathyroidism
0.000 0.846 0.154
K90.9 Intestinal malabsorption, unspecified
0.000 0.850 0.150
I10-I15 Hypertensive diseases
0.000 0.851 0.149
E89.3 Postprocedural hypopituitarism
0.000 0.854 0.146
E85.4 Organ-limited amyloidosis
0.001 0.857 0.142
E56 Other vitamin deficiencies
0.000 0.860 0.140
E64 Sequelae of malnutrition and other nutritional deficiencies
0.001 0.865 0.135
E63 Other nutritional deficiencies
0.001 0.865 0.135
E50 Vitamin A deficiency
0.001 0.865 0.135
E60 Dietary zinc deficiency
0.001 0.865 0.135
E59 Dietary selenium deficiency
0.001 0.865 0.135
E54 Ascorbic acid deficiency
0.001 0.865 0.135
E52 Niacin deficiency [pellagra]
0.001 0.865 0.135
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.865 0.135
E58 Dietary calcium deficiency
0.001 0.868 0.131
E85.3 Secondary systemic amyloidosis
0.001 0.869 0.131
E85.9 Amyloidosis, unspecified
0.001 0.869 0.131
E03 Other hypothyroidism
0.000 0.871 0.129
E51 Thiamine deficiency
0.001 0.872 0.127
E89.0 Postprocedural hypothyroidism
0.000 0.873 0.127
E05.9 Thyrotoxicosis, unspecified
0.000 0.874 0.126
E14.9 Without complications
0.000 0.875 0.125
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.877 0.122
E00 Congenital iodine-deficiency syndrome
0.000 0.877 0.122
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.886 0.114
I11 Hypertensive heart disease
0.000 0.886 0.114
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.890 0.109
I13 Hypertensive heart and renal disease
0.000 0.893 0.107
E56.1 Deficiency of vitamin K
0.000 0.894 0.105
E05.8 Other thyrotoxicosis
0.000 0.895 0.105
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.897 0.103
E56.9 Vitamin deficiency, unspecified
0.000 0.899 0.100
E56.8 Deficiency of other vitamins
0.000 0.899 0.100
E56.0 Deficiency of vitamin E
0.000 0.899 0.100
E86 Volume depletion
0.000 0.900 0.100
E50.9 Vitamin A deficiency, unspecified
0.001 0.903 0.097
E50.8 Other manifestations of vitamin A deficiency
0.001 0.903 0.097
E50.7 Other ocular manifestations of vitamin A deficiency
0.001 0.903 0.097
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.001 0.903 0.097
E50.5 Vitamin A deficiency with night blindness
0.001 0.903 0.097
E50.4 Vitamin A deficiency with keratomalacia
0.001 0.903 0.097
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.001 0.903 0.097
E50.2 Vitamin A deficiency with corneal xerosis
0.001 0.903 0.097
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.001 0.903 0.097
E50.0 Vitamin A deficiency with conjunctival xerosis
0.001 0.903 0.097
E63.9 Nutritional deficiency, unspecified
0.001 0.903 0.097
E63.8 Other specified nutritional deficiencies
0.001 0.903 0.097
E63.1 Imbalance of constituents of food intake
0.001 0.903 0.097
E63.0 Essential fatty acid [EFA] deficiency
0.001 0.903 0.097
E64.9 Sequelae of unspecified nutritional deficiency
0.001 0.903 0.097
E64.8 Sequelae of other nutritional deficiencies
0.001 0.903 0.097
E64.3 Sequelae of rickets
0.001 0.903 0.097
E64.2 Sequelae of vitamin C deficiency
0.001 0.903 0.097
E64.1 Sequelae of vitamin A deficiency
0.001 0.903 0.097
E64.0 Sequelae of protein-energy malnutrition
0.001 0.903 0.097
E06 Thyroiditis
0.000 0.903 0.097
E05.5 Thyroid crisis or storm
0.000 0.903 0.097
E05.4 Thyrotoxicosis factitia
0.000 0.903 0.097
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.903 0.097
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.903 0.097
E03.5 Myxoedema coma
0.000 0.907 0.093
E03.4 Atrophy of thyroid (acquired)
0.000 0.907 0.093
E03.3 Postinfectious hypothyroidism
0.000 0.907 0.093
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.907 0.093
E03.1 Congenital hypothyroidism without goitre
0.000 0.907 0.093
E61 Deficiency of other nutrient elements
0.001 0.907 0.092
E51.9 Thiamine deficiency, unspecified
0.001 0.908 0.091
E51.8 Other manifestations of thiamine deficiency
0.001 0.908 0.091
E51.1 Beriberi
0.001 0.908 0.091
E53 Deficiency of other B group vitamins
0.000 0.909 0.090
E03.8 Other specified hypothyroidism
0.000 0.909 0.090
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.912 0.088
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.912 0.088
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.912 0.088
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.912 0.088
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.912 0.088
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.912 0.088
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.912 0.088
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.912 0.088
E51.2 Wernicke's encephalopathy
0.001 0.915 0.084
E55 Vitamin D deficiency
0.001 0.916 0.083
I15 Secondary hypertension
0.000 0.918 0.082
E06.3 Autoimmune thyroiditis
0.000 0.921 0.079
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.922 0.078
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.923 0.077
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.923 0.077
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.923 0.077
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.925 0.075
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.926 0.073
E06.4 Drug-induced thyroiditis
0.000 0.930 0.070
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.930 0.070
E06.0 Acute thyroiditis
0.000 0.930 0.070
E07 Other disorders of thyroid
0.000 0.930 0.070
E87.5 Hyperkalaemia
0.000 0.930 0.070
E61.9 Deficiency of nutrient element, unspecified
0.001 0.933 0.066
E61.8 Deficiency of other specified nutrient elements
0.001 0.933 0.066
E61.7 Deficiency of multiple nutrient elements
0.001 0.933 0.066
E61.6 Vanadium deficiency
0.001 0.933 0.066
E61.5 Molybdenum deficiency
0.001 0.933 0.066
E61.4 Chromium deficiency
0.001 0.933 0.066
E61.3 Manganese deficiency
0.001 0.933 0.066
E61.0 Copper deficiency
0.001 0.933 0.066
E53.1 Pyridoxine deficiency
0.000 0.935 0.065
E53.0 Riboflavin deficiency
0.000 0.935 0.065
E03.9 Hypothyroidism, unspecified
0.000 0.936 0.064
E20-E35 Disorders of other endocrine glands
0.000 0.936 0.064
E61.2 Magnesium deficiency
0.001 0.938 0.062
E06.5 Other chronic thyroiditis
0.000 0.939 0.061
I15.9 Seconday hypertension, unspecified
0.000 0.939 0.061
E55.0 Rickets, active
0.001 0.940 0.059
I15.8 Other secondary hypertension
0.000 0.941 0.059
E66 Obesity
0.000 0.941 0.059
E53.9 Vitamin B deficiency, unspecified
0.000 0.941 0.058
E06.9 Thyroiditis, unspecified
0.000 0.941 0.059
I15.2 Hypertension secondary to endocrine disorders
0.000 0.942 0.058
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.943 0.057
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.943 0.057
E87.3 Alkalosis
0.000 0.943 0.057
I15.0 Renovascular hypertension
0.000 0.944 0.056
E06.1 Subacute thyroiditis
0.000 0.945 0.055
E87.4 Mixed disorder of acid-base balance
0.000 0.946 0.054
E87.0 Hyperosmolality and hypernatraemia
0.000 0.946 0.054
I83 Varicose veins of lower extremities
0.000 0.948 0.052
E20 Hypoparathyroidism
0.000 0.949 0.051
E07.1 Dyshormogenetic goitre
0.000 0.950 0.050
E07.0 Hypersecretion of calcitonin
0.000 0.950 0.050
E29 Testicular dysfunction
0.000 0.951 0.049
I12 Hypertensive renal disease
0.000 0.952 0.048
E25 Adrenogenital disorders
0.000 0.952 0.048
E78.1 Pure hyperglyceridaemia
0.000 0.953 0.047
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.954 0.046
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.954 0.046
E32 Diseases of thymus
0.000 0.954 0.046
E31 Polyglandular dysfunction
0.000 0.954 0.046
E30 Disorders of puberty, not elsewhere classified
0.000 0.954 0.046
E78.4 Other hyperlipidaemia
0.000 0.955 0.045
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.955 0.044
E78.6 Lipoprotein deficiency
0.000 0.957 0.043
E26 Hyperaldosteronism
0.000 0.957 0.043
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.957 0.043
E66.1 Drug-induced obesity
0.000 0.958 0.042
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.958 0.042
E20.9 Hypoparathyroidism, unspecified
0.000 0.959 0.041
E07.8 Other specified disorders of thyroid
0.000 0.959 0.041
E34 Other endocrine disorders
0.000 0.959 0.041
E78.3 Hyperchylomicronaemia
0.000 0.960 0.040
I15.1 Hypertension secondary to other renal disorders
0.000 0.960 0.039
E29.1 Testicular hypofunction
0.000 0.960 0.040
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.961 0.039
D45 Polycythaemia vera
0.000 0.962 0.037
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.963 0.037
E20.8 Other hypoparathyroidism
0.000 0.963 0.036
E20.1 Pseudohypoparathyroidism
0.000 0.963 0.036
E20.0 Idiopathic hypoparathyroidism
0.000 0.963 0.036
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.964 0.036
E27 Other disorders of adrenal gland
0.000 0.964 0.036
E29.8 Other testicular dysfunction
0.000 0.965 0.035
E29.0 Testicular hyperfunction
0.000 0.965 0.035
E25.9 Adrenogenital disorder, unspecified
0.000 0.966 0.034
E25.8 Other adrenogenital disorders
0.000 0.966 0.034
E53.8 Deficiency of other specified B group vitamins
0.000 0.966 0.034
E61.1 Iron deficiency
0.001 0.967 0.033
E30.9 Disorder of puberty, unspecified
0.000 0.967 0.033
E30.8 Other disorders of puberty
0.000 0.967 0.033
E30.1 Precocious puberty
0.000 0.967 0.033
E30.0 Delayed puberty
0.000 0.967 0.033
E31.9 Polyglandular dysfunction, unspecified
0.000 0.967 0.033
E31.8 Other polyglandular dysfunction
0.000 0.967 0.033
E31.1 Polyglandular hyperfunction
0.000 0.967 0.033
E31.0 Autoimmune polyglandular failure
0.000 0.967 0.033
E32.9 Disease of thymus, unspecified
0.000 0.967 0.033
E32.8 Other diseases of thymus
0.000 0.967 0.033
E32.1 Abscess of thymus
0.000 0.967 0.033
E32.0 Persistent hyperplasia of thymus
0.000 0.967 0.033
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.967 0.033
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.967 0.033
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.967 0.033
E29.9 Testicular dysfunction, unspecified
0.000 0.967 0.033
E34.9 Endocrine disorder, unspecified
0.000 0.967 0.033
E26.9 Hyperaldosteronism, unspecified
0.000 0.967 0.032
E21.2 Other hyperparathyroidism
0.000 0.967 0.032
E78.8 Other disorders of lipoprotein metabolism
0.000 0.968 0.031
R40.0 Somnolence
0.031 0.969 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.969 0.031
E26.8 Other hyperaldosteronism
0.000 0.969 0.031
E26.1 Secondary hyperaldosteronism
0.000 0.969 0.031
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.969 0.031
E21.4 Other specified disorders of parathyroid gland
0.000 0.969 0.031
E28 Ovarian dysfunction
0.000 0.969 0.030
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.970 0.030
E34.5 Androgen resistance syndrome
0.000 0.970 0.029
E34.4 Constitutional tall stature
0.000 0.970 0.029
E34.3 Short stature, not elsewhere classified
0.000 0.970 0.029
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.970 0.029
E34.1 Other hypersecretion of intestinal hormones
0.000 0.970 0.029
E34.8 Other specified endocrine disorders
0.000 0.971 0.029
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.971 0.029
E24 Cushing's syndrome
0.000 0.971 0.029
E78.2 Mixed hyperlipidaemia
0.000 0.972 0.028
E66.0 Obesity due to excess calories
0.000 0.972 0.028
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.972 0.027
E22 Hyperfunction of pituitary gland
0.000 0.972 0.027
E27.1 Primary adrenocortical insufficiency
0.000 0.972 0.028
D46 Myelodysplastic syndromes
0.000 0.974 0.026
D37-D48 Neoplasms of uncertain or unknown behaviour
0.000 0.974 0.026
E26.0 Primary hyperaldosteronism
0.000 0.974 0.026
E27.5 Adrenomedullary hyperfunction
0.000 0.974 0.026
E27.0 Other adrenocortical overactivity
0.000 0.974 0.026
I12.9 Hypertensive renal disease without renal failure
0.000 0.974 0.025
E21.0 Primary hyperparathyroidism
0.000 0.975 0.025
D46.9 Myelodysplastic syndrome, unspecified
0.000 0.975 0.025
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.000 0.976 0.024
E27.2 Addisonian crisis
0.000 0.976 0.023
D46.4 Refractory anaemia, unspecified
0.000 0.977 0.023
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.000 0.977 0.023
D39.1 Ovary
0.000 0.978 0.022
K90-K93 Other diseases of the digestive system
0.000 0.978 0.022
E28.9 Ovarian dysfunction, unspecified
0.000 0.978 0.022
E28.8 Other ovarian dysfunction
0.000 0.978 0.022
E28.1 Androgen excess
0.000 0.978 0.022
E28.0 Oestrogen excess
0.000 0.978 0.022
E22.1 Hyperprolactinaemia
0.000 0.978 0.022
E27.9 Disorder of adrenal gland, unspecified
0.000 0.978 0.022
D46.2 Refractory anaemia with excess of blasts
0.000 0.978 0.021
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.000 0.979 0.021
E24.2 Drug-induced Cushing's syndrome
0.000 0.979 0.021
E27.8 Other specified disorders of adrenal gland
0.000 0.979 0.021
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.979 0.021
E24.3 Ectopic ACTH syndrome
0.000 0.979 0.021
E24.1 Nelson's syndrome
0.000 0.979 0.021
E07.9 Disorder of thyroid, unspecified
0.000 0.979 0.020
E28.3 Primary ovarian failure
0.000 0.980 0.020
D46.7 Other myelodysplastic syndromes
0.000 0.980 0.020
D44.3 Pituitary gland
0.000 0.980 0.020
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.980 0.020
E22.8 Other hyperfunction of pituitary gland
0.000 0.980 0.020
D46.1 Refractory anaemia with sideroblasts
0.000 0.980 0.020
E23 Hypofunction and other disorders of pituitary gland
0.000 0.980 0.020
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
0.000 0.981 0.019
D46.5 Refractory anaemia with multi-lineage dysplasia
0.000 0.981 0.019
D46.3 Refractory anaemia with excess of blasts with transformation
0.000 0.981 0.019
D46.0 Refractory anaemia without sideroblasts, so stated
0.000 0.981 0.019
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.981 0.019
E34.0 Carcinoid syndrome
0.000 0.981 0.018
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.000 0.981 0.019
E24.0 Pituitary-dependent Cushing's disease
0.000 0.981 0.018
L40.5 Arthropathic psoriasis
0.019 0.981 0.000
D37.7 Other digestive organs
0.000 0.982 0.018
D44.7 Aortic body and other paraganglia
0.000 0.982 0.018
D37.3 Appendix
0.000 0.982 0.018
D44.0 Thyroid gland
0.000 0.982 0.018
E24.8 Other Cushing's syndrome
0.000 0.982 0.017
D39.7 Other female genital organs
0.000 0.983 0.017
D39.0 Uterus
0.000 0.983 0.017
D39.9 Female genital organ, unspecified
0.000 0.983 0.017
D39.2 Placenta
0.000 0.983 0.017
E04 Other non-toxic goitre
0.000 0.983 0.017
D37.4 Colon
0.000 0.983 0.017
D44.6 Carotid body
0.000 0.983 0.017
D37.6 Liver, gallbladder and bile ducts
0.000 0.983 0.017
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.983 0.017
D44.5 Pineal gland
0.000 0.984 0.016
D44.2 Parathyroid gland
0.000 0.984 0.016
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.984 0.016
E87.2 Acidosis
0.000 0.984 0.016
E22.0 Acromegaly and pituitary gigantism
0.000 0.984 0.015
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.984 0.016
D44.9 Endocrine gland, unspecified
0.000 0.984 0.016
D37.1 Stomach
0.000 0.984 0.016
D47.3 Essential (haemorrhagic) thrombocythaemia
0.000 0.984 0.016
D44.1 Adrenal gland
0.000 0.984 0.016
D44.4 Craniopharyngeal duct
0.000 0.985 0.015
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.000 0.985 0.015
D37.9 Digestive organ, unspecified
0.000 0.985 0.015
D44.8 Pluriglandular involvement
0.000 0.985 0.015
E24.9 Cushing's syndrome, unspecified
0.000 0.985 0.014
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.000 0.985 0.015
D75.1 Secondary polycythaemia
0.000 0.985 0.015
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.000 0.986 0.014
D47.2 Monoclonal gammopathy
0.000 0.986 0.014
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.986 0.014
E23.1 Drug-induced hypopituitarism
0.000 0.986 0.014
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.000 0.986 0.014
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.000 0.986 0.014
D42.9 Meninges, unspecified
0.000 0.986 0.014
D42.1 Spinal meninges
0.000 0.986 0.014
D42.0 Cerebral meninges
0.000 0.986 0.014
E23.7 Disorder of pituitary gland, unspecified
0.000 0.986 0.013
M07.39 Other psoriatic arthropathies (Site unspecified)
0.013 0.987 0.000
D37.2 Small intestine
0.000 0.987 0.013
D38.5 Other respiratory organs
0.000 0.987 0.013
E21.3 Hyperparathyroidism, unspecified
0.000 0.987 0.013
E04.8 Other specified non-toxic goitre
0.000 0.987 0.012
T51.0 Ethanol
0.000 0.988 0.012
D86.9 Sarcoidosis, unspecified
0.000 0.988 0.012
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.988 0.012
E23.6 Other disorders of pituitary gland
0.000 0.988 0.012
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.988 0.012
K93.1 Megacolon in Chagas' disease
0.000 0.988 0.012
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.988 0.012
D47.4 Osteomyelofibrosis
0.000 0.988 0.012

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

The contents of TreeWAS.org are available under the Creative Commons Attribution 4.0 International License (CC BY 4.0) with attribution (citation) required.

TreeWAS Database © 2019 - 2024 About Frequently Asked Questions Citation Contact Terms & Conditions This website does not use cookies to collect any personal information about you.