TreeWAS – Variant ID: rs4425311

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.999	0.001
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.998	0.002
T40.2 Other opioids	0.997	0.003
T85 Complications of other internal prosthetic devices, implants and grafts	0.984	0.016
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.980	0.020
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.976	0.024
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.971	0.029
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.951	0.049
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.949	0.051
S90-S99 Injuries to the ankle and foot	0.945	0.055
T42.4 Benzodiazepines	0.929	0.071
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.927	0.073
T51 Toxic effect of alcohol	0.926	0.074
S80-S89 Injuries to the knee and lower leg	0.913	0.087
T51.0 Ethanol	0.912	0.088
S20-S29 Injuries to the thorax	0.912	0.088
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.893	0.107
T20-T25 Burns and corrosions of external body surface, specified by site	0.887	0.113
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.870	0.130
T84.1 Mechanical complication of internal fixation device of bones of limb	0.868	0.132
S22 Fracture of rib(s), sternum and thoracic spine	0.858	0.142
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.857	0.143
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.852	0.148
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.851	0.149
T43.2 Other and unspecified antidepressants	0.847	0.153
T42.1 Iminostilbenes	0.843	0.157
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.837	0.162
S90 Superficial injury of ankle and foot	0.834	0.166
T15-T19 Effects of foreign body entering through natural orifice	0.833	0.167
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.833	0.167
T46 Poisoning by agents primarily affecting the cardiovascular system	0.832	0.168
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.818	0.182
S10-S19 Injuries to the neck	0.813	0.187
S92 Fracture of foot, except ankle	0.813	0.187
T43.0 Tricyclic and tetracyclic antidepressants	0.805	0.195
T82.0 Mechanical complication of heart valve prosthesis	0.805	0.195
S22.4 Multiple fractures of ribs	0.804	0.196
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.795	0.205
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.794	0.206
T82.4 Mechanical complication of vascular dialysis catheter	0.791	0.209
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.786	0.214
T86 Failure and rejection of transplanted organs and tissues	0.780	0.220
T50.9 Other and unspecified drugs, medicaments and biological substances	0.777	0.223
S50-S59 Injuries to the elbow and forearm	0.777	0.223
S22.0 Fracture of thoracic vertebra	0.771	0.229
T83.1 Mechanical complication of other urinary devices and implants	0.769	0.231
T00-T07 Injuries involving multiple body regions	0.769	0.231
T36 Poisoning by systemic antibiotics	0.768	0.231
S22.40 Multiple fractures of ribs (closed)	0.765	0.235
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.764	0.236
T43.5 Other and unspecified antipsychotics and neuroleptics	0.764	0.236
T83.3 Mechanical complication of intra-uterine contraceptive device	0.761	0.239
S89 Other and unspecified injuries of lower leg	0.759	0.241
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.757	0.243
T85.4 Mechanical complication of breast prosthesis and implant	0.756	0.243
T39.0 Salicylates	0.753	0.247
S80 Superficial injury of lower leg	0.751	0.249
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.751	0.249
S91 Open wound of ankle and foot	0.749	0.251
S90.9 Superficial injury of ankle and foot, unspecified	0.749	0.251
T79-T79 Certain early complications of trauma	0.749	0.251
T85.2 Mechanical complication of intraocular lens	0.747	0.253
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.746	0.254
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.745	0.255
T84.3 Mechanical complication of other bone devices, implants and grafts	0.740	0.260
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.739	0.260
T21 Burn and corrosion of trunk	0.735	0.265
S81 Open wound of lower leg	0.732	0.268
T80 Complications following infusion, transfusion and therapeutic injection	0.726	0.274
T39.1 4-Aminophenol derivatives	0.723	0.277
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.723	0.277
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.722	0.278
T47.1 Other antacids and anti-gastric-secretion drugs	0.721	0.279
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.720	0.280
S92.3 Fracture of metatarsal bone	0.720	0.280
T46.1 Calcium-channel blockers	0.717	0.283
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.717	0.283
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.717	0.283
T41 Poisoning by anaesthetics and therapeutic gases	0.717	0.283
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T56 Toxic effect of metals	0.716	0.283
S86 Injury of muscle and tendon at lower leg level	0.716	0.284
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.715	0.284
T40.8 Lysergide [LSD]	0.715	0.284
T40.7 Cannabis (derivatives)	0.715	0.284
T40.5 Cocaine	0.715	0.284
T40.3 Methadone	0.715	0.284
T40.1 Heroin	0.715	0.284
T40.0 Opium	0.715	0.284
T16 Foreign body in ear	0.713	0.287
S22.00 Fracture of thoracic vertebra (closed)	0.710	0.290
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.706	0.294
T88 Other complications of surgical and medical care, not elsewhere classified	0.705	0.295
T40.6 Other and unspecified narcotics	0.703	0.297
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.703	0.297
T84.2 Mechanical complication of internal fixation device of other bones	0.701	0.299
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.700	0.300
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.700	0.300
T42.5 Mixed antiepileptics, not elsewhere classified	0.700	0.300
T42.3 Barbiturates	0.700	0.300
T42.2 Succinimides and oxazolidinediones	0.700	0.300
T42.0 Hydantoin derivatives	0.700	0.300
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.699	0.301
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.699	0.301
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.694	0.306
T40.4 Other synthetic narcotics	0.693	0.307
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.692	0.308
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.688	0.312
T43.3 Phenothiazine antipsychotics and neuroleptics	0.685	0.315
S99 Other and unspecified injuries of ankle and foot	0.683	0.317
T65 Toxic effect of other and unspecified substances	0.682	0.318
T62 Toxic effect of other noxious substances eaten as food	0.682	0.318
T61 Toxic effect of noxious substances eaten as seafood	0.682	0.318
T60 Toxic effect of pesticides	0.682	0.318
T57 Toxic effect of other inorganic substances	0.682	0.318
T54 Toxic effect of corrosive substances	0.682	0.318
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.682	0.318
T52 Toxic effect of organic solvents	0.682	0.318
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.682	0.318
T55 Toxic effect of soaps and detergents	0.682	0.318
T43.9 Psychotropic drug, unspecified	0.680	0.320
T43.8 Other psychotropic drugs, not elsewhere classified	0.680	0.320
T43.6 Psychostimulants with abuse potential	0.680	0.320
T43.4 Butyrophenone and thioxanthene neuroleptics	0.680	0.320
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.680	0.320
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.678	0.322
S98 Traumatic amputation of ankle and foot	0.677	0.323
S97 Crushing injury of ankle and foot	0.677	0.323
S96 Injury of muscle and tendon at ankle and foot level	0.677	0.323
S95 Injury of blood vessels at ankle and foot level	0.677	0.323
S94 Injury of nerves at ankle and foot level	0.677	0.323
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.673	0.327
T59 Toxic effect of other gases, fumes and vapours	0.668	0.332
S27 Injury of other and unspecified intrathoracic organs	0.666	0.334
T20 Burn and corrosion of head and neck	0.666	0.334
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.665	0.335
T51.8 Other alcohols	0.664	0.336
T51.3 Fusel oil	0.664	0.336
T51.2 2-Propanol	0.664	0.336
T51.1 Methanol	0.664	0.336
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.659	0.341
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.655	0.345
S88 Traumatic amputation of lower leg	0.654	0.346
S87 Crushing injury of lower leg	0.654	0.346
S85 Injury of blood vessels at lower leg level	0.654	0.346
S84 Injury of nerves at lower leg level	0.654	0.346
S92.30 Fracture of metatarsal bone (closed)	0.654	0.346
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.654	0.346
S26 Injury of heart	0.654	0.346
S25 Injury of blood vessels of thorax	0.654	0.346
S24 Injury of nerves and spinal cord at thorax level	0.654	0.346
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.654	0.346
S21 Open wound of thorax	0.654	0.346
S89.9 Unspecified injury of lower leg	0.649	0.351
T23 Burn and corrosion of wrist and hand	0.648	0.352
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.646	0.353
S11 Open wound of neck	0.645	0.355
S80.9 Superficial injury of lower leg, unspecified	0.644	0.356
S20 Superficial injury of thorax	0.644	0.356
S90.3 Contusion of other and unspecified parts of foot	0.643	0.357
S12 Fracture of neck	0.642	0.358
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.640	0.360
T39.4 Antirheumatics, not elsewhere classified	0.640	0.360
T39.2 Pyrazolone derivatives	0.640	0.360
T25 Burn and corrosion of ankle and foot	0.636	0.364
T63 Toxic effect of contact with venomous animals	0.632	0.368
S82 Fracture of lower leg, including ankle	0.632	0.368
T21.0 Burn of unspecified degree of trunk	0.627	0.373
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.626	0.374
S81.8 Open wound of other parts of lower leg	0.625	0.375
T17 Foreign body in respiratory tract	0.624	0.376
T50.8 Diagnostic agents	0.624	0.376
T50.7 Analeptics and opioid receptor antagonists	0.624	0.376
T50.6 Antidotes and chelating agents, not elsewhere classified	0.624	0.376
T50.5 Appetite depressants	0.624	0.376
T50.4 Drugs affecting uric acid metabolism	0.624	0.376
T50.3 Electrolytic, caloric and water-balance agents	0.624	0.376
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.624	0.376
T50.1 Loop [high-ceiling] diuretics	0.624	0.376
T50.0 Mineralocorticoids and their antagonists	0.624	0.376
S91.1 Open wound of toe(s) without damage to nail	0.623	0.377
S70-S79 Injuries to the hip and thigh	0.622	0.378
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.621	0.379
T86.1 Kidney transplant failure and rejection	0.619	0.381
S22.9 Fracture of bony thorax, part unspecified	0.615	0.385
S22.8 Fracture of other parts of bony thorax	0.615	0.385
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.611	0.389
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.611	0.389
T83.2 Mechanical complication of graft of urinary organ	0.611	0.389
S92.7 Multiple fractures of foot	0.609	0.391
S51 Open wound of forearm	0.609	0.391
T58 Toxic effect of carbon monoxide	0.608	0.391
S92.5 Fracture of other toe	0.608	0.392
S29 Other and unspecified injuries of thorax	0.607	0.393
T36.0 Penicillins	0.603	0.397
T00 Superficial injuries involving multiple body regions	0.601	0.399
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.601	0.399
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.600	0.399
T47.8 Other agents primarily affecting the gastro-intestinal system	0.600	0.399
T47.7 Emetics	0.600	0.399
T47.6 Antidiarrhoeal drugs	0.600	0.399
T47.5 Digestants	0.600	0.399
T47.4 Other laxatives	0.600	0.399
T47.3 Saline and osmotic laxatives	0.600	0.399
T47.2 Stimulant laxatives	0.600	0.399
T47.0 Histamine H(2)-receptor antagonists	0.600	0.399
T46.4 Angiotensin-converting-enzyme inhibitors	0.600	0.400
S90.7 Multiple superficial injuries of ankle and foot	0.598	0.402
S90.2 Contusion of toe(s) with damage to nail	0.598	0.402
S90.1 Contusion of toe(s) without damage to nail	0.598	0.402
S90.0 Contusion of ankle	0.598	0.402
T19 Foreign body in genito-urinary tract	0.597	0.402
T15 Foreign body on external eye	0.597	0.402
S92.1 Fracture of talus	0.597	0.402
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.597	0.403
T46.8 Antivaricose drugs, including sclerosing agents	0.597	0.403
T46.7 Peripheral vasodilators	0.597	0.403
T46.5 Other antihypertensive drugs, not elsewhere classified	0.597	0.403
T46.3 Coronary vasodilators, not elsewhere classified	0.597	0.403
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.597	0.403
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.597	0.403
S50 Superficial injury of forearm	0.593	0.407
S92.4 Fracture of great toe	0.590	0.410
T38.9 Other and unspecified hormone antagonists	0.587	0.413
T38.8 Other and unspecified hormones and their synthetic substitutes	0.587	0.413
T38.7 Androgens and anabolic congeners	0.587	0.413
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.587	0.413
T38.5 Other oestrogens and progestogens	0.587	0.413
T38.4 Oral contraceptives	0.587	0.413
T38.2 Antithyroid drugs	0.587	0.413
T38.1 Thyroid hormones and substitutes	0.587	0.413
T38.0 Glucocorticoids and synthetic analogues	0.587	0.413
T82.1 Mechanical complication of cardiac electronic device	0.583	0.417
S17 Crushing injury of neck	0.583	0.417
S15 Injury of blood vessels at neck level	0.583	0.417
S18 Traumatic amputation at neck level	0.583	0.417
S16 Injury of muscle and tendon at neck level	0.583	0.417
S92.9 Fracture of foot, unspecified	0.583	0.417
T51.9 Alcohol, unspecified	0.582	0.417
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.582	0.418
S22.5 Flail chest	0.581	0.419
T87 Complications peculiar to reattachment and amputation	0.581	0.419
S22.1 Multiple fractures of thoracic spine	0.579	0.420
S22.41 Multiple fractures of ribs (open)	0.576	0.424
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.575	0.424
S86.8 Injury of other muscles and tendons at lower leg level	0.575	0.424
T45.0 Antiallergic and antiemetic drugs	0.571	0.429
T86.0 Bone-marrow transplant rejection	0.570	0.430
T79 Certain early complications of trauma, not elsewhere classified	0.570	0.430
T18 Foreign body in alimentary tract	0.569	0.431
S82.3 Fracture of lower end of tibia	0.567	0.433
S80.0 Contusion of knee	0.567	0.433
T88.7 Unspecified adverse effect of drug or medicament	0.566	0.434
S10 Superficial injury of neck	0.565	0.435
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.563	0.437
S22.2 Fracture of sternum	0.563	0.437
S81.0 Open wound of knee	0.562	0.438
T66-T78 Other and unspecified effects of external causes	0.562	0.438
T82.3 Mechanical complication of other vascular grafts	0.559	0.440
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.559	0.441
T86.4 Liver transplant failure and rejection	0.559	0.441
T86.3 Heart-lung transplant failure and rejection	0.559	0.441
T86.2 Heart transplant failure and rejection	0.559	0.441
S90.8 Other superficial injuries of ankle and foot	0.558	0.442
S59 Other and unspecified injuries of forearm	0.557	0.443
S58 Traumatic amputation of forearm	0.557	0.443
S57 Crushing injury of forearm	0.557	0.443
S55 Injury of blood vessels at forearm level	0.557	0.443
S54 Injury of nerves at forearm level	0.557	0.443
S56 Injury of muscle and tendon at forearm level	0.555	0.445
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.555	0.445
T02 Fractures involving multiple body regions	0.554	0.446
S22.01 Fracture of thoracic vertebra (open)	0.553	0.447
T86.8 Failure and rejection of other transplanted organs and tissues	0.552	0.448
S14 Injury of nerves and spinal cord at neck level	0.551	0.449
T06 Other injuries involving multiple body regions, not elsewhere classified	0.551	0.449
T05 Traumatic amputations involving multiple body regions	0.551	0.449
T04 Crushing injuries involving multiple body regions	0.551	0.449
T03 Dislocations, sprains and strains involving multiple body regions	0.551	0.449
T01 Open wounds involving multiple body regions	0.551	0.449
T07 Unspecified multiple injuries	0.551	0.449
T36.9 Systemic antibiotic, unspecified	0.551	0.449
T36.8 Other systemic antibiotics	0.551	0.449
T36.7 Antifungal antibiotics, systemically used	0.551	0.449
T36.6 Rifamycins	0.551	0.449
T36.5 Aminoglycosides	0.551	0.449
T36.4 Tetracyclines	0.551	0.449
T36.3 Macrolides	0.551	0.449
T36.2 Chloramphenicol group	0.551	0.449
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.551	0.449
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.551	0.449
S22.3 Fracture of rib	0.549	0.451
T56.8 Other metals	0.548	0.452
T80.2 Infections following infusion, transfusion and therapeutic injection	0.545	0.455
S92.0 Fracture of calcaneus	0.545	0.455
S89.8 Other specified injuries of lower leg	0.544	0.456
S89.7 Multiple injuries of lower leg	0.544	0.456
S89.1 Other specified injuries of lower leg	0.544	0.456
S89.0 Multiple injuries of lower leg	0.544	0.456
T45.1 Antineoplastic and immunosuppressive drugs	0.540	0.460
S80.7 Multiple superficial injuries of lower leg	0.538	0.461
T45.9 Primarily systemic and haematological agent, unspecified	0.538	0.462
T45.8 Other primarily systemic and haematological agents	0.538	0.462
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.538	0.462
T45.6 Fibrinolysis-affecting drugs	0.538	0.462
T45.5 Anticoagulants	0.538	0.462
T45.4 Iron and its compounds	0.538	0.462
T45.3 Enzymes, not elsewhere classified	0.538	0.462
T45.2 Vitamins, not elsewhere classified	0.538	0.462
S91.7 Multiple open wounds of ankle and foot	0.537	0.463
S91.2 Open wound of toe(s) with damage to nail	0.537	0.463
S91.0 Open wound of ankle	0.537	0.463
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.535	0.465
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.534	0.466
S27.1 Traumatic haemothorax	0.534	0.466
S92.2 Fracture of other tarsal bone(s)	0.533	0.467
S80.1 Contusion of other and unspecified parts of lower leg	0.530	0.470
T21.7 Corrosion of third degree of trunk	0.527	0.473
T21.6 Corrosion of second degree of trunk	0.527	0.473
T21.5 Corrosion of first degree of trunk	0.527	0.473
T21.4 Corrosion of unspecified degree of trunk	0.527	0.473
T21.3 Burn of third degree of trunk	0.527	0.473
T21.2 Burn of second degree of trunk	0.527	0.473
T21.1 Burn of first degree of trunk	0.527	0.473
S81.7 Multiple open wounds of lower leg	0.525	0.475
S11.9 Open wound of neck, part unspecified	0.524	0.476
S82.1 Fracture of upper end of tibia	0.523	0.477
S93.0 Dislocation of ankle joint	0.522	0.477
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.521	0.479
T80.6 Other serum reactions	0.521	0.479
T80.5 Anaphylactic shock due to serum	0.521	0.479
T80.4 Rh incompatibility reaction	0.521	0.479
T80.3 ABO incompatibility reaction	0.521	0.479
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.521	0.479
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.521	0.479
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.518	0.482
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.518	0.482
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.518	0.482
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.518	0.482
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.518	0.482
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.518	0.482
T44.1 Other parasympathomimetics [cholinergics]	0.518	0.482
T44.0 Anticholinesterase agents	0.518	0.482
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.516	0.483
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.516	0.483
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.516	0.483
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.516	0.483
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.516	0.483
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.516	0.483
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.516	0.483
S92.31 Fracture of metatarsal bone (open)	0.516	0.484
S13.4 Sprain and strain of cervical spine	0.516	0.484
S82.30 Fracture of lower end of tibia (closed)	0.515	0.485
S91.3 Open wound of other parts of foot	0.514	0.486
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.514	0.486
T37.8 Other specified systemic anti-infectives and antiparasitics	0.514	0.486
T37.5 Antiviral drugs	0.514	0.486
T37.4 Anthelminthics	0.514	0.486
T37.3 Other antiprotozoal drugs	0.514	0.486
T37.2 Antimalarials and drugs acting on other blood protozoa	0.514	0.486
T37.1 Antimycobacterial drugs	0.514	0.486
T37.0 Sulphonamides	0.514	0.486
T41.5 Therapeutic gases	0.514	0.486
T41.4 Anaesthetic, unspecified	0.514	0.486
T41.3 Local anaesthetics	0.514	0.486
T41.2 Other and unspecified general anaesthetics	0.514	0.486
T41.1 Intravenous anaesthetics	0.514	0.486
T41.0 Inhaled anaesthetics	0.514	0.486
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.514	0.486
T48.6 Antiasthmatics, not elsewhere classified	0.514	0.486
T48.5 Anti-common-cold drugs	0.514	0.486
T48.4 Expectorants	0.514	0.486
T48.3 Antitussives	0.514	0.486
T48.2 Other and unspecified agents primarily acting on muscles	0.514	0.486
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.514	0.486
T48.0 Oxytocic drugs	0.514	0.486
T49.9 Topical agent, unspecified	0.514	0.486
T49.8 Other topical agents	0.514	0.486
T49.7 Dental drugs, topically applied	0.514	0.486
T49.6 Otorhinolaryngological drugs and preparations	0.514	0.486
T49.5 Ophthalmological drugs and preparations	0.514	0.486
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.514	0.486
T49.3 Emollients, demulcents and protectants	0.514	0.486
T49.2 Local astringents and local detergents	0.514	0.486
T49.1 Antipruritics	0.514	0.486
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.514	0.486
T28 Burn and corrosion of other internal organs	0.514	0.486
T27 Burn and corrosion of respiratory tract	0.514	0.486
T26 Burn and corrosion confined to eye and adnexa	0.514	0.486
T35 Frostbite involving multiple body regions and unspecified frostbite	0.514	0.486
T34 Frostbite with tissue necrosis	0.514	0.486
T33 Superficial frostbite	0.514	0.486
T56.9 Metal, unspecified	0.514	0.486
T56.7 Beryllium and its compounds	0.514	0.486
T56.6 Tin and its compounds	0.514	0.486
T56.5 Zinc and its compounds	0.514	0.486
T56.4 Copper and its compounds	0.514	0.486
T56.3 Cadmium and its compounds	0.514	0.486
T56.2 Chromium and its compounds	0.514	0.486
T56.1 Mercury and its compounds	0.514	0.486
T56.0 Lead and its compounds	0.514	0.486
S86.0 Injury of Achilles tendon	0.513	0.486
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.513	0.486
S86.7 Injury of multiple muscles and tendons at lower leg level	0.513	0.486
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.513	0.486
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.513	0.486
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.513	0.486
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.510	0.490
S20.8 Superficial injuries of other and unspecified parts of thorax	0.509	0.491
T20.2 Burn of second degree of head and neck	0.508	0.492
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.505	0.495
T88.9 Complication of surgical and medical care, unspecified	0.505	0.495
T88.5 Other complications of anaesthesia	0.505	0.495
T88.3 Malignant hyperthermia due to anaesthesis	0.505	0.495
T88.2 Shock due to anaesthesia	0.505	0.495
T88.1 Other complications following immunisation, not elsewhere classified	0.505	0.495
T88.0 Infection following immunisation	0.505	0.495
S52 Fracture of forearm	0.504	0.496
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.504	0.496
T17.2 Foreign body in pharynx	0.500	0.500
S27.2 Traumatic heamopneumothorax	0.498	0.502
S12.2 Fracture of other specified cervical vertebra	0.497	0.503
S99.9 Unspecified injury of ankle and foot	0.496	0.504
S80.8 Other superficial injuries of lower leg	0.495	0.505
S12.1 Fracture of second cervical vertebra	0.495	0.505
T83.0 Mechanical complication of urinary (indwelling) catheter	0.494	0.506
S51.7 Multiple open wounds of forearm	0.491	0.509
S20.3 Other superficial injuries of front wall of thorax	0.490	0.509
S99.8 Other specified injuries of ankle and foot	0.490	0.510
S99.7 Multiple injuries of ankle and foot	0.490	0.510
T52.9 Organic solvent, unspecified	0.489	0.511
T52.8 Other organic solvents	0.489	0.511
T52.4 Ketones	0.489	0.511
T52.3 Glycols	0.489	0.511
T52.2 Homologues of benzene	0.489	0.511
T52.1 Benzene	0.489	0.511
T52.0 Petroleum products	0.489	0.511
T53.9 Halogen derivative of aliphatic and aromatic hydrocarbons, unspecified	0.489	0.511
T53.7 Other halogen derivatives of aromatic hydrocarbons	0.489	0.511
T53.6 Other halogen derivatives of aliphatic hydrocarbons	0.489	0.511
T53.5 Chlorofluorocarbons	0.489	0.511
T53.4 Dichloromethane	0.489	0.511
T53.3 Tetrachloroethylene	0.489	0.511
T53.2 Trichloroethylene	0.489	0.511
T53.1 Chloroform	0.489	0.511
T53.0 Carbon tetrachloride	0.489	0.511
T54.9 Corrosive substance, unspecified	0.489	0.511
T54.3 Corrosive alkalis and alklali-like substances	0.489	0.511
T54.2 Corrosive acids and acid-like substances	0.489	0.511
T54.1 Other corrosive organic compounds	0.489	0.511
T54.0 Phenol and phenol homologues	0.489	0.511
T57.9 Inorganic substance, unspecified	0.489	0.511
T57.8 Other specified inorganic substances	0.489	0.511
T57.3 Hydrogen cyanide	0.489	0.511
T57.2 Manganese and its compounds	0.489	0.511
T57.1 Phosphorus and its compounds	0.489	0.511
T57.0 Arsenic and its compounds	0.489	0.511
T60.9 Pesticide, unspecified	0.489	0.511
T60.8 Other pesticides	0.489	0.511
T60.4 Rodenticides	0.489	0.511
T60.3 Herbicides and fungicides	0.489	0.511
T60.2 Other insecticides	0.489	0.511
T60.1 Halogenated insecticides	0.489	0.511
T60.0 Organophosphate and carbamate insecticides	0.489	0.511
T61.9 Toxic effect of unspecified seafood	0.489	0.511
T61.8 Toxic effect of other seafoods	0.489	0.511
T61.2 Other fish and shellfish poisoning	0.489	0.511
T61.1 Scombroid fish poisoning	0.489	0.511
T61.0 Ciguatera fish poisoning	0.489	0.511
T62.9 Noxious substance eaten as food, unspecified	0.489	0.511
T62.8 Other specified noxious substances eaten as food	0.489	0.511
T62.2 Other ingested (parts of) plant(s)	0.489	0.511
T62.1 Ingested berries	0.489	0.511
T62.0 Ingested mushrooms	0.489	0.511
T65.9 Toxic effect of unspecified substance	0.489	0.511
T65.8 Toxic effect of other specified substances	0.489	0.511
T65.6 Paints and dyes, not elsewhere classified	0.489	0.511
T65.5 Nitroglycerin and other nitric acids and esters	0.489	0.511
T65.4 Carbon disulphide	0.489	0.511
T65.3 Nitroderivatives and aminoderivatives of benzene and its homologues	0.489	0.511
T65.2 Tobacco and nicotine	0.489	0.511
T65.1 Strychnine and its salts	0.489	0.511
T65.0 Cyanides	0.489	0.511
S00-S09 Injuries to the head	0.489	0.511
S13.5 Sprain and strain of thyroid region	0.486	0.514
S13.3 Multiple dislocations of neck	0.486	0.514
S13.2 Dislocation of other and unspecified parts of neck	0.486	0.514
S13.1 Dislocation of cervical vertebra	0.486	0.514
S13.0 Traumatic rupture of cervical intervertebral disk	0.486	0.514
S94.9 Injury of unspecified nerve at ankle and foot level	0.485	0.514
S94.8 Injury of other nerves at ankle and foot level	0.485	0.514
S94.7 Injury of multiple nerves at ankle and foot level	0.485	0.514
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.485	0.514
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.485	0.514
S94.1 Injury of medial plantar nerve	0.485	0.514
S94.0 Injury of lateral plantar nerve	0.485	0.514

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations