TreeWAS – Variant ID: rs4444235

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.780	0.220	0.000
D12.3 Transverse colon	0.775	0.225	0.000
D12.6 Colon, unspecified	0.773	0.227	0.000
D12.8 Rectum	0.759	0.241	0.000
D12.0 Caecum	0.725	0.275	0.000
D12.5 Sigmoid colon	0.717	0.283	0.000
E11 Non-insulin-dependent diabetes mellitus	0.704	0.296	0.000
E10-E14 Diabetes mellitus	0.689	0.311	0.000
E10 Insulin-dependent diabetes mellitus	0.686	0.314	0.000
E10.3 With ophthalmic complications	0.678	0.322	0.000
D12.9 Anus and anal canal	0.659	0.341	0.000
E11.0 With coma	0.659	0.341	0.000
E11.3 With ophthalmic complications	0.647	0.353	0.000
E11.5 With peripheral circulatory complications	0.644	0.356	0.000
E10.2 With renal complications	0.643	0.357	0.000
E11.2 With renal complications	0.642	0.358	0.000
E11.1 With ketoacidosis	0.630	0.370	0.000
D12.4 Descending colon	0.614	0.386	0.000
E10.5 With peripheral circulatory complications	0.592	0.408	0.000
E11.6 With other specified complications	0.591	0.409	0.000
E13 Other specified diabetes mellitus	0.587	0.413	0.000
E10.6 With other specified complications	0.565	0.435	0.000
E11.4 With neurological complications	0.559	0.441	0.000
E11.7 With multiple complications	0.549	0.451	0.000
E10.4 With neurological complications	0.539	0.461	0.000
E10.7 With multiple complications	0.535	0.465	0.000
E10.0 With coma	0.530	0.470	0.000
D12.1 Appendix	0.509	0.491	0.000
E12 Malnutrition-related diabetes mellitus	0.494	0.506	0.000
E13.9 Without complications	0.492	0.508	0.000
E11.8 With unspecified complications	0.462	0.538	0.000
E13.3 With ophthalmic complications	0.460	0.539	0.000
E14 Unspecified diabetes mellitus	0.445	0.555	0.000
E10.8 With unspecified complications	0.436	0.564	0.000
E13.8 With unspecified complications	0.421	0.579	0.000
E13.7 With multiple complications	0.421	0.579	0.000
E13.6 With other specified complications	0.421	0.579	0.000
E13.5 With peripheral circulatory complications	0.421	0.579	0.000
E13.4 With neurological complications	0.421	0.579	0.000
E13.2 With renal complications	0.421	0.579	0.000
E13.1 With ketoacidosis	0.421	0.579	0.000
E13.0 With coma	0.421	0.579	0.000
E14.6 With other specified complications	0.372	0.628	0.000
E12.9 Without complications	0.354	0.646	0.000
E12.8 With unspecified complications	0.354	0.646	0.000
E12.7 With multiple complications	0.354	0.646	0.000
E12.6 With other specified complications	0.354	0.646	0.000
E12.5 With peripheral circulatory complications	0.354	0.646	0.000
E12.4 With neurological complications	0.354	0.646	0.000
E12.3 With ophthalmic complications	0.354	0.646	0.000
E12.2 With renal complications	0.354	0.646	0.000
E12.1 With ketoacidosis	0.354	0.646	0.000
E12.0 With coma	0.354	0.646	0.000
E14.1 With ketoacidosis	0.328	0.672	0.000
E14.5 With peripheral circulatory complications	0.327	0.673	0.000
E14.7 With multiple complications	0.319	0.681	0.000
E14.0 With coma	0.319	0.681	0.000
E14.3 With ophthalmic complications	0.308	0.692	0.000
E14.4 With neurological complications	0.305	0.694	0.000
E14.8 With unspecified complications	0.301	0.698	0.000
E14.2 Withrenal complications	0.300	0.700	0.000
E14.9 Without complications	0.227	0.773	0.000
E11.9 Without complications	0.152	0.848	0.000
E10.1 With ketoacidosis	0.126	0.873	0.001
D12.2 Ascending colon	0.126	0.874	0.000
D12.7 Rectosigmoid junction	0.095	0.904	0.001
H52.1 Myopia	0.080	0.920	0.000
E10.9 Without complications	0.021	0.979	0.000
N39.8 Other specified disorders of urinary system	0.000	0.982	0.018
H36.0 Diabetic retinopathy	0.017	0.983	0.000
H52 Disorders of refraction and accommodation	0.016	0.984	0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.014	0.986	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.014	0.986	0.000
H52.7 Disorder of refraction, unspecified	0.013	0.987	0.000
H52.4 Presbyopia	0.012	0.988	0.000
H52.6 Other disorders of refraction	0.011	0.988	0.000
H52.5 Disorders of accommodation	0.011	0.988	0.000
T78.2 Anaphylactic shock, unspecified	0.011	0.989	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.010	0.990	0.000
T78 Adverse effects, not elsewhere classified	0.010	0.990	0.000
T78.3 Angioneurotic oedema	0.010	0.990	0.000
L91.8 Other hypertrophic disorders of skin	0.010	0.990	0.000
H49 Paralytic strabismus	0.010	0.990	0.000
H52.3 Anisometropia and aniseikonia	0.010	0.990	0.000
E40-E46 Malnutrition	0.009	0.990	0.000
H49.2 Sixth [abducent] nerve palsy	0.010	0.990	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.009	0.991	0.000
T78.4 Allergy, unspecified	0.009	0.991	0.000
H51 Other disorders of binocular movement	0.008	0.991	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.008	0.992	0.000
H36 Retinal disorders in diseases classified elsewhere	0.008	0.992	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.008	0.992	0.000
E50-E64 Other nutritional deficiencies	0.008	0.992	0.000
E20-E35 Disorders of other endocrine glands	0.008	0.992	0.000
T78.8 Other adverse effects, not elsewhere classified	0.008	0.992	0.000
H49.8 Other paralytic strabismus	0.008	0.992	0.000
E28 Ovarian dysfunction	0.008	0.992	0.000
H49.0 Third [oculomotor] nerve palsy	0.007	0.993	0.000
H49.1 Fourth [trochlear] nerve palsy	0.007	0.993	0.000
H51.9 Disorder of binocular movement, unspecified	0.007	0.993	0.000
T78.9 Adverse effect, unspecified	0.007	0.993	0.000
H49.3 Total (external) ophthalmoplegia	0.007	0.993	0.000
H49.9 Paralytic strabismus, unspecified	0.007	0.993	0.000
E65-E68 Obesity and other hyperalimentation	0.007	0.993	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.007	0.993	0.000
E45 Retarded development following protein-energy malnutrition	0.007	0.993	0.000
E43 Unspecified severe protein-energy malnutrition	0.007	0.993	0.000
E42 Marasmic kwashiorkor	0.007	0.993	0.000
E41 Nutritional marasmus	0.007	0.993	0.000
E40 Kwashiorkor	0.007	0.993	0.000
H49.4 Progressive external ophthalmoplegia	0.007	0.993	0.000
E28.2 Polycystic ovarian syndrome	0.007	0.993	0.000
E23 Hypofunction and other disorders of pituitary gland	0.007	0.993	0.000
E61 Deficiency of other nutrient elements	0.007	0.993	0.000
R82.9 Other and unspecified abnormal finding in urine	0.000	0.993	0.007
E46 Unspecified protein-energy malnutrition	0.007	0.993	0.000
E32 Diseases of thymus	0.006	0.993	0.000
H51.2 Internuclear ophthalmoplegia	0.006	0.993	0.000
E28.3 Primary ovarian failure	0.006	0.994	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.006	0.994	0.000
E23.6 Other disorders of pituitary gland	0.006	0.994	0.000
H51.8 Other specified disorders of binocular movement	0.006	0.994	0.000
H51.1 Convergence insufficiency and excess	0.006	0.994	0.000
H51.0 Palsy of conjugate gaze	0.006	0.994	0.000
E34 Other endocrine disorders	0.006	0.994	0.000
E26 Hyperaldosteronism	0.006	0.994	0.000
R09.2 Respiratory arrest	0.000	0.994	0.006
H36.8 Other retinal disorders in diseases classified elsewhere	0.006	0.994	0.000
E15 Nondiabetic hypoglycaemic coma	0.006	0.994	0.000
E31 Polyglandular dysfunction	0.006	0.994	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.006	0.994	0.000
E63 Other nutritional deficiencies	0.006	0.994	0.000
E50 Vitamin A deficiency	0.006	0.994	0.000
E60 Dietary zinc deficiency	0.006	0.994	0.000
E59 Dietary selenium deficiency	0.006	0.994	0.000
E52 Niacin deficiency [pellagra]	0.006	0.994	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.006	0.994	0.000
E30 Disorders of puberty, not elsewhere classified	0.006	0.994	0.000
E27 Other disorders of adrenal gland	0.006	0.994	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.006	0.994	0.000
E51 Thiamine deficiency	0.006	0.994	0.000
E56 Other vitamin deficiencies	0.006	0.994	0.000
E65 Localised adiposity	0.006	0.994	0.000
E55 Vitamin D deficiency	0.006	0.994	0.000
O47.0 False labour before 37 completed weeks of gestation	0.000	0.994	0.006
E58 Dietary calcium deficiency	0.006	0.994	0.000
E28.9 Ovarian dysfunction, unspecified	0.006	0.994	0.000
E28.8 Other ovarian dysfunction	0.006	0.994	0.000
E28.1 Androgen excess	0.006	0.994	0.000
E28.0 Oestrogen excess	0.006	0.994	0.000
E34.0 Carcinoid syndrome	0.006	0.994	0.000
E61.2 Magnesium deficiency	0.006	0.994	0.000
E00-E07 Disorders of thyroid gland	0.006	0.994	0.000
E54 Ascorbic acid deficiency	0.005	0.994	0.000
E67 Other hyperalimentation	0.005	0.995	0.000
E68 Sequelae of hyperalimentation	0.005	0.995	0.000
E06.3 Autoimmune thyroiditis	0.005	0.995	0.000
H52.2 Astigmatism	0.005	0.995	0.000
E25 Adrenogenital disorders	0.005	0.995	0.000
E61.1 Iron deficiency	0.005	0.995	0.000
E06 Thyroiditis	0.005	0.995	0.000
E27.8 Other specified disorders of adrenal gland	0.005	0.995	0.000
E44.1 Mild protein-energy malnutrition	0.005	0.995	0.000
E44.0 Moderate protein-energy malnutrition	0.005	0.995	0.000
E32.8 Other diseases of thymus	0.005	0.995	0.000
E21.0 Primary hyperparathyroidism	0.005	0.995	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.005	0.995	0.000
E23.1 Drug-induced hypopituitarism	0.005	0.995	0.000
E61.9 Deficiency of nutrient element, unspecified	0.005	0.995	0.000
E61.8 Deficiency of other specified nutrient elements	0.005	0.995	0.000
E61.7 Deficiency of multiple nutrient elements	0.005	0.995	0.000
E61.6 Vanadium deficiency	0.005	0.995	0.000
E61.5 Molybdenum deficiency	0.005	0.995	0.000
E61.4 Chromium deficiency	0.005	0.995	0.000
E61.3 Manganese deficiency	0.005	0.995	0.000
E61.0 Copper deficiency	0.005	0.995	0.000
E23.0 Hypopituitarism	0.005	0.995	0.000
E23.2 Diabetes insipidus	0.005	0.995	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.005	0.995	0.000
E53 Deficiency of other B group vitamins	0.005	0.995	0.000
E21.4 Other specified disorders of parathyroid gland	0.005	0.995	0.000
E20 Hypoparathyroidism	0.005	0.995	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.005	0.995	0.000
E26.0 Primary hyperaldosteronism	0.005	0.995	0.000
E32.9 Disease of thymus, unspecified	0.005	0.995	0.000
E32.1 Abscess of thymus	0.005	0.995	0.000
E32.0 Persistent hyperplasia of thymus	0.005	0.995	0.000
J92.9 Pleural plaque without asbestos	0.000	0.995	0.005
E34.5 Androgen resistance syndrome	0.005	0.995	0.000
E34.4 Constitutional tall stature	0.005	0.995	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.005	0.995	0.000
E34.1 Other hypersecretion of intestinal hormones	0.005	0.995	0.000
E26.9 Hyperaldosteronism, unspecified	0.005	0.995	0.000
E26.8 Other hyperaldosteronism	0.005	0.995	0.000
E26.1 Secondary hyperaldosteronism	0.005	0.995	0.000
E27.9 Disorder of adrenal gland, unspecified	0.005	0.995	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.005	0.995	0.000
E31.0 Autoimmune polyglandular failure	0.005	0.995	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.005	0.995	0.000
E31.9 Polyglandular dysfunction, unspecified	0.005	0.995	0.000
E31.8 Other polyglandular dysfunction	0.005	0.995	0.000
E31.1 Polyglandular hyperfunction	0.005	0.995	0.000
E34.3 Short stature, not elsewhere classified	0.005	0.995	0.000
E50.9 Vitamin A deficiency, unspecified	0.004	0.995	0.000
E50.8 Other manifestations of vitamin A deficiency	0.004	0.995	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.004	0.995	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.004	0.995	0.000
E50.5 Vitamin A deficiency with night blindness	0.004	0.995	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.004	0.995	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.004	0.995	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.004	0.995	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.004	0.995	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.004	0.995	0.000
E63.9 Nutritional deficiency, unspecified	0.004	0.995	0.000
E63.8 Other specified nutritional deficiencies	0.004	0.995	0.000
E63.1 Imbalance of constituents of food intake	0.004	0.995	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.004	0.995	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.004	0.995	0.000
E64.8 Sequelae of other nutritional deficiencies	0.004	0.995	0.000
E64.3 Sequelae of rickets	0.004	0.995	0.000
E64.2 Sequelae of vitamin C deficiency	0.004	0.995	0.000
E64.1 Sequelae of vitamin A deficiency	0.004	0.995	0.000
E64.0 Sequelae of protein-energy malnutrition	0.004	0.995	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.005	0.995	0.000
E06.5 Other chronic thyroiditis	0.005	0.995	0.000
E27.5 Adrenomedullary hyperfunction	0.005	0.995	0.000
E27.0 Other adrenocortical overactivity	0.005	0.995	0.000
E30.9 Disorder of puberty, unspecified	0.004	0.995	0.000
E30.8 Other disorders of puberty	0.004	0.995	0.000
E30.1 Precocious puberty	0.004	0.995	0.000
E30.0 Delayed puberty	0.004	0.995	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.004	0.995	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.004	0.995	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.004	0.995	0.000
H72 Perforation of tympanic membrane	0.005	0.995	0.000
E34.8 Other specified endocrine disorders	0.005	0.995	0.000
E51.9 Thiamine deficiency, unspecified	0.004	0.995	0.000
E51.8 Other manifestations of thiamine deficiency	0.004	0.995	0.000
E51.1 Beriberi	0.004	0.995	0.000
E56.9 Vitamin deficiency, unspecified	0.004	0.995	0.000
E56.8 Deficiency of other vitamins	0.004	0.995	0.000
E56.0 Deficiency of vitamin E	0.004	0.995	0.000
E23.7 Disorder of pituitary gland, unspecified	0.004	0.995	0.000
J42 Unspecified chronic bronchitis	0.000	0.995	0.005
S42.30 Fracture of shaft of humerus (closed)	0.000	0.995	0.005
K31.7 Polyp of stomach and duodenum	0.005	0.995	0.000
E29 Testicular dysfunction	0.004	0.995	0.000
E21.2 Other hyperparathyroidism	0.004	0.995	0.000
E51.2 Wernicke's encephalopathy	0.004	0.995	0.000
E24 Cushing's syndrome	0.004	0.995	0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.000	0.995	0.005
E56.1 Deficiency of vitamin K	0.004	0.995	0.000
E55.0 Rickets, active	0.004	0.995	0.000
E16 Other disorders of pancreatic internal secretion	0.004	0.996	0.000
E27.2 Addisonian crisis	0.004	0.996	0.000
H50.8 Other specified strabismus	0.004	0.996	0.000
H72.0 Central perforation of tympanic membrane	0.004	0.996	0.000
E07 Other disorders of thyroid	0.004	0.996	0.000
H50 Other strabismus	0.004	0.996	0.000
E21.3 Hyperparathyroidism, unspecified	0.004	0.996	0.000
E34.9 Endocrine disorder, unspecified	0.004	0.996	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.004	0.996	0.000
E00 Congenital iodine-deficiency syndrome	0.004	0.996	0.000
E04.2 Non-toxic multinodular goitre	0.004	0.996	0.000
H72.1 Attic perforation of tympanic membrane	0.004	0.996	0.000
K70.3 Alcoholic cirrhosis of liver	0.004	0.996	0.000
E67.8 Other specified hyperalimentation	0.004	0.996	0.000
E67.3 Hypervitaminosis D	0.004	0.996	0.000
E67.2 Megavitamin-B6 syndrome	0.004	0.996	0.000
E67.1 Hypercarotenaemia	0.004	0.996	0.000
E67.0 Hypervitaminosis A	0.004	0.996	0.000
J39.8 Other specified diseases of upper respiratory tract	0.004	0.996	0.000
E06.4 Drug-induced thyroiditis	0.004	0.996	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.004	0.996	0.000
E06.0 Acute thyroiditis	0.004	0.996	0.000
E25.9 Adrenogenital disorder, unspecified	0.004	0.996	0.000
E25.8 Other adrenogenital disorders	0.004	0.996	0.000
E55.9 Vitamin D deficiency, unspecified	0.004	0.996	0.000
H72.2 Other marginal perforations of tympanic membrane	0.004	0.996	0.000
E06.1 Subacute thyroiditis	0.004	0.996	0.000
E53.9 Vitamin B deficiency, unspecified	0.004	0.996	0.000
E53.1 Pyridoxine deficiency	0.004	0.996	0.000
E53.0 Riboflavin deficiency	0.004	0.996	0.000
K70.1 Alcoholic hepatitis	0.004	0.996	0.000
E20.8 Other hypoparathyroidism	0.004	0.996	0.000
E20.1 Pseudohypoparathyroidism	0.004	0.996	0.000
E20.0 Idiopathic hypoparathyroidism	0.004	0.996	0.000
H71 Cholesteatoma of middle ear	0.004	0.996	0.000
K70 Alcoholic liver disease	0.004	0.996	0.000
E07.8 Other specified disorders of thyroid	0.004	0.996	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.004	0.996	0.000
H65-H75 Diseases of middle ear and mastoid	0.004	0.996	0.000
E06.9 Thyroiditis, unspecified	0.003	0.996	0.000
E24.0 Pituitary-dependent Cushing's disease	0.003	0.996	0.000
E29.9 Testicular dysfunction, unspecified	0.003	0.996	0.000
E29.8 Other testicular dysfunction	0.003	0.996	0.000
E29.0 Testicular hyperfunction	0.003	0.996	0.000
F01.9 Vascular dementia, unspecified	0.004	0.996	0.000
H50.2 Vertical strabismus	0.003	0.996	0.000
E22 Hyperfunction of pituitary gland	0.003	0.996	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.003	0.996	0.000
E24.3 Ectopic ACTH syndrome	0.003	0.996	0.000
E24.1 Nelson's syndrome	0.003	0.996	0.000
N10 Acute tubulo-interstitial nephritis	0.000	0.996	0.004
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.003	0.996	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.003	0.997	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.003	0.997	0.000
E16.4 Abnormal secretion of gastrin	0.003	0.997	0.000
E16.3 Increased secretion of glucagon	0.003	0.997	0.000
H50.4 Other and unspecified heterotropia	0.003	0.997	0.000
H70 Mastoiditis and related conditions	0.003	0.997	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.003	0.997	0.000
H74.4 Polyp of middle ear	0.003	0.997	0.000
H50.3 Intermittent heterotropia	0.003	0.997	0.000
E07.1 Dyshormogenetic goitre	0.003	0.997	0.000
E07.0 Hypersecretion of calcitonin	0.003	0.997	0.000
E24.9 Cushing's syndrome, unspecified	0.003	0.997	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.003	0.997	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.003	0.997	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.003	0.997	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.003	0.997	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.003	0.997	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.003	0.997	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.003	0.997	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.003	0.997	0.000
K70.4 Alcoholic hepatic failure	0.003	0.997	0.000
Z76.9 Persons encountering health services in unspecified circumstances	0.003	0.997	0.000
E24.8 Other Cushing's syndrome	0.003	0.997	0.000
H74 Other disorders of middle ear and mastoid	0.003	0.997	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.003	0.997	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.003	0.997	0.000
H50.6 Mechanical strabismus	0.003	0.997	0.000
E27.1 Primary adrenocortical insufficiency	0.003	0.997	0.000
K50.1 Crohn's disease of large intestine	0.000	0.997	0.003
E16.1 Other hypoglycaemia	0.003	0.997	0.000
E04 Other non-toxic goitre	0.003	0.997	0.000
H50.5 Heterophoria	0.003	0.997	0.000
C69.3 Choroid	0.003	0.997	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.003	0.997	0.000
H70.0 Acute mastoiditis	0.003	0.997	0.000
H70.9 Mastoiditis, unspecified	0.003	0.997	0.000
H70.1 Chronic mastoiditis	0.003	0.997	0.000
H68 Eustachian salpingitis and obstruction	0.003	0.997	0.000
J92 Pleural plaque	0.000	0.997	0.003
C69.9 Eye, unspecified	0.003	0.997	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.002	0.997	0.000
K70.9 Alcoholic liver disease, unspecified	0.003	0.997	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.003	0.997	0.000
H67 Otitis media in diseases classified elsewhere	0.003	0.997	0.000
I84.5 External haemorrhoids without complication	0.000	0.997	0.003
H69 Other disorders of Eustachian tube	0.003	0.997	0.000
T66-T78 Other and unspecified effects of external causes	0.003	0.997	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.003	0.997	0.000
J92.0 Pleural plaque with presence of asbestos	0.000	0.997	0.003
E22.8 Other hyperfunction of pituitary gland	0.003	0.997	0.000
H54.4 Blindness, one eye	0.003	0.997	0.000
H52.0 Hypermetropia	0.002	0.997	0.001
E07.9 Disorder of thyroid, unspecified	0.003	0.997	0.000
E20.9 Hypoparathyroidism, unspecified	0.002	0.997	0.000
H70.2 Petrositis	0.003	0.997	0.000
J03.9 Acute tonsillitis, unspecified	0.000	0.997	0.003
S82.30 Fracture of lower end of tibia (closed)	0.003	0.997	0.000
H74.0 Tympanosclerosis	0.003	0.997	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.003	0.997	0.000
T91.1 Sequelae of fracture of spine	0.003	0.997	0.000
E03 Other hypothyroidism	0.003	0.997	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.002	0.997	0.000
H74.1 Adhesive middle ear disease	0.002	0.997	0.000
E24.2 Drug-induced Cushing's syndrome	0.002	0.997	0.001
H70.8 Other mastoiditis and related conditions	0.002	0.997	0.000
K70.0 Alcoholic fatty liver	0.002	0.997	0.000
E04.8 Other specified non-toxic goitre	0.002	0.997	0.000
M34.9 Systemic sclerosis, unspecified	0.003	0.997	0.000
C69 Malignant neoplasm of eye and adnexa	0.002	0.997	0.000
H68.1 Obstruction of Eustachian tube	0.002	0.997	0.000
T45.0 Antiallergic and antiemetic drugs	0.000	0.997	0.002
H33 Retinal detachments and breaks	0.003	0.997	0.000
C51.9 Vulva, unspecified	0.002	0.998	0.000
E53.8 Deficiency of other specified B group vitamins	0.002	0.998	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.002	0.998	0.000
T71 Asphyxiation	0.002	0.998	0.000
B25.9 Cytomegaloviral disease, unspecified	0.002	0.998	0.000
E87.2 Acidosis	0.002	0.998	0.000
H33.5 Other retinal detachments	0.002	0.998	0.000
H33.4 Traction detachment of retina	0.002	0.998	0.000
H69.8 Other specified disorders of Eustachian tube	0.002	0.998	0.000
H72.8 Other perforations of tympanic membrane	0.002	0.998	0.000
H66 Suppurative and unspecified otitis media	0.002	0.998	0.000
H68.0 Eustachian salpingitis	0.002	0.998	0.000
K76.6 Portal hypertension	0.002	0.998	0.000
H50.0 Convergent concomitant strabismus	0.002	0.998	0.000
S42.3 Fracture of shaft of humerus	0.000	0.998	0.002
T66 Unspecified effects of radiation	0.002	0.998	0.000
H33.1 Retinoschisis and retinal cysts	0.002	0.998	0.000
E03.1 Congenital hypothyroidism without goitre	0.002	0.998	0.000
E22.1 Hyperprolactinaemia	0.002	0.998	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.002	0.998	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.002	0.998	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.002	0.998	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.002	0.998	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.002	0.998	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
H69.0 Patulous Eustachian tube	0.002	0.998	0.000
T74 Maltreatment syndromes	0.002	0.998	0.000
T73 Effects of other deprivation	0.002	0.998	0.000
T69 Other effects of reduced temperature	0.002	0.998	0.000
T67 Effects of heat and light	0.002	0.998	0.000
H73 Other disorders of tympanic membrane	0.002	0.998	0.000
H33.2 Serous retinal detachment	0.002	0.998	0.000
H33.0 Retinal detachment with retinal break	0.002	0.998	0.000
L28.0 Lichen simplex chronicus	0.000	0.998	0.002
M50.1 Cervical disk disorder with radiculopathy	0.000	0.998	0.002
T91.2 Sequelae of other fracture of thorax and pelvis	0.002	0.998	0.000
Z96.2 Presence of otological and audiological implants	0.002	0.998	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.000	0.998	0.002
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.002	0.998	0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.002	0.998	0.000
H66.4 Suppurative otitis media, unspecified	0.002	0.998	0.000
I44.1 Atrioventricular block, second degree	0.002	0.998	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.002	0.998	0.000
G72.9 Myopathy, unspecified	0.002	0.998	0.000
C69.2 Retina	0.002	0.998	0.000
E03.5 Myxoedema coma	0.002	0.998	0.000
E03.4 Atrophy of thyroid (acquired)	0.002	0.998	0.000
E03.3 Postinfectious hypothyroidism	0.002	0.998	0.000
M14.6 Neuropathic arthropathy	0.002	0.998	0.000
T75 Effects of other external causes	0.002	0.998	0.000
H69.9 Eustachian tube disorder, unspecified	0.002	0.998	0.000
T70 Effects of air pressure and water pressure	0.002	0.998	0.000
H30-H36 Disorders of choroid and retina	0.002	0.998	0.000
E04.0 Non-toxic diffuse goitre	0.002	0.998	0.000
X49.9 Unspecified place	0.002	0.998	0.000
T91 Sequelae of injuries of neck and trunk	0.002	0.998	0.000
C69.0 Conjunctiva	0.002	0.998	0.000
T90.9 Sequelae of unspecified injury of head	0.002	0.998	0.000
C69.8 Overlapping lesion of eye and adnexa	0.002	0.998	0.000
C69.5 Lachrymal gland and duct	0.002	0.998	0.000
C69.4 Ciliary body	0.002	0.998	0.000
C69.1 Cornea	0.002	0.998	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.002	0.998	0.000
H95.1 Other disorders following mastoidectomy	0.002	0.998	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.002	0.998	0.000
S42.31 Fracture of shaft of humerus (open)	0.000	0.998	0.002
H73.9 Disorder of tympanic membrane, unspecified	0.002	0.998	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.002	0.998	0.000
H66.0 Acute suppurative otitis media	0.002	0.998	0.000
S02.60 Fracture of mandible (closed)	0.002	0.998	0.000
H73.1 Chronic myringitis	0.002	0.998	0.000
M06.0 Seronegative rheumatoid arthritis	0.002	0.998	0.000
C44.4 Skin of scalp and neck	0.002	0.998	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.002	0.998	0.000
R82 Other abnormal findings in urine	0.000	0.998	0.002
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.002	0.998	0.000
H26.9 Cataract, unspecified	0.002	0.998	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.002	0.998	0.000
J05.1 Acute epiglottitis	0.002	0.998	0.000
M67.8 Other specified disorders of synovium and tendon	0.002	0.998	0.000
T67.9 Effects of heat and light, unspecified	0.002	0.998	0.000
T67.8 Other effects of heat and light	0.002	0.998	0.000
T67.7 Heat oedema	0.002	0.998	0.000
T67.6 Heat fatigue, transient	0.002	0.998	0.000
T67.5 Heat exhaustion, unspecified	0.002	0.998	0.000
T67.4 Heat exhaustion due to salt depletion	0.002	0.998	0.000
T67.3 Heat exhaustion, anhydrotic	0.002	0.998	0.000
T67.2 Heat cramp	0.002	0.998	0.000
T67.1 Heat syncope	0.002	0.998	0.000
T67.0 Heatstroke and sunstroke	0.002	0.998	0.000
T69.9 Effect of reduced temperature, unspecified	0.002	0.998	0.000
T69.8 Other specified effects of reduced temperature	0.002	0.998	0.000
T69.1 Chilblains	0.002	0.998	0.000
T69.0 Immersion hand and foot	0.002	0.998	0.000
T73.9 Effect of deprivation, unspecified	0.002	0.998	0.000
T73.8 Other effects of deprivation	0.002	0.998	0.000
T73.3 Exhaustion due to excessive exertion	0.002	0.998	0.000
T73.2 Exhaustion due to exposure	0.002	0.998	0.000
T73.1 Effects of thirst	0.002	0.998	0.000
T73.0 Effects of hunger	0.002	0.998	0.000
T74.9 Maltreatment syndrome, unspecified	0.002	0.998	0.000
T74.8 Other maltreatment syndromes	0.002	0.998	0.000
T74.3 Psychological abuse	0.002	0.998	0.000
T74.2 Sexual abuse	0.002	0.998	0.000
T74.1 Physical abuse	0.002	0.998	0.000
T74.0 Neglect or abandonment	0.002	0.998	0.000
R34 Anuria and oliguria	0.002	0.998	0.000
H73.0 Acute myringitis	0.002	0.998	0.000
E88 Other metabolic disorders	0.002	0.998	0.000
E29.1 Testicular hypofunction	0.002	0.998	0.000
E16.2 Hypoglycaemia, unspecified	0.002	0.998	0.000
E88.2 Lipomatosis, not elsewhere classified	0.002	0.998	0.000
H50.9 Strabismus, unspecified	0.002	0.998	0.000
H66.3 Other chronic suppurative otitis media	0.002	0.998	0.000
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters	0.000	0.998	0.002
H66.1 Chronic tubotympanic suppurative otitis media	0.002	0.998	0.000
B97 Viral agents as the cause of diseases classified to other chapters	0.000	0.998	0.002
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.002	0.998	0.000
A40.0 Septicaemia due to streptococcus, group A	0.002	0.998	0.000
C69.6 Orbit	0.002	0.998	0.000
T75.8 Other specified effects of external causes	0.002	0.998	0.000
T75.3 Motion sickness	0.002	0.998	0.000
T75.2 Effects of vibration	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations