TreeWAS – Variant ID: rs4444878

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I26.9 Pulmonary embolism without mention of acute cor pulmonale	1.000	0.000	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	1.000	0.000	0.000
Z86.7 Personal history of diseases of the circulatory system	1.000	0.000	0.000
Z92.1 Personal history of long-term (current) use of anticoagulants	0.999	0.001	0.000
I80 Phlebitis and thrombophlebitis	0.692	0.308	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.683	0.317	0.000
I26 Pulmonary embolism	0.635	0.365	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.554	0.445	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.432	0.567	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.402	0.598	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.358	0.642	0.000
I27 Other pulmonary heart diseases	0.346	0.654	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.335	0.664	0.000
I28 Other diseases of pulmonary vessels	0.305	0.695	0.000
I27.2 Other secondary pulmonary hypertension	0.292	0.708	0.000
I27.0 Primary pulmonary hypertension	0.284	0.716	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.251	0.749	0.000
I27.1 Kyphoscoliotic heart disease	0.248	0.752	0.000
I27.9 Pulmonary heart disease, unspecified	0.241	0.759	0.000
I27.8 Other specified pulmonary heart diseases	0.239	0.760	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.227	0.773	0.000
I28.1 Aneurysm of pulmonary artery	0.219	0.781	0.000
I28.8 Other specified diseases of pulmonary vessels	0.181	0.818	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.158	0.841	0.001
H73.8 Other specified disorders of tympanic membrane	0.000	0.909	0.091
H73 Other disorders of tympanic membrane	0.000	0.926	0.074
H65-H75 Diseases of middle ear and mastoid	0.000	0.941	0.059
Z50.1 Other physical therapy	0.000	0.943	0.057
H73.1 Chronic myringitis	0.000	0.944	0.056
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.947	0.053
H73.0 Acute myringitis	0.000	0.947	0.053
H71 Cholesteatoma of middle ear	0.000	0.947	0.052
H74 Other disorders of middle ear and mastoid	0.000	0.948	0.052
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.951	0.049
H70 Mastoiditis and related conditions	0.000	0.953	0.047
H65 Nonsuppurative otitis media	0.000	0.955	0.045
H74.4 Polyp of middle ear	0.000	0.956	0.044
H68 Eustachian salpingitis and obstruction	0.000	0.956	0.044
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.958	0.042
H67 Otitis media in diseases classified elsewhere	0.000	0.958	0.042
H74.1 Adhesive middle ear disease	0.000	0.959	0.041
H66 Suppurative and unspecified otitis media	0.000	0.959	0.041
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.960	0.040
H70.9 Mastoiditis, unspecified	0.000	0.962	0.038
H65.0 Acute serous otitis media	0.000	0.962	0.038
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.963	0.037
H65.4 Other chronic nonsuppurative otitis media	0.000	0.963	0.037
H70.8 Other mastoiditis and related conditions	0.000	0.964	0.036
H66.3 Other chronic suppurative otitis media	0.000	0.964	0.036
H70.1 Chronic mastoiditis	0.000	0.965	0.035
H65.1 Other acute nonsuppurative otitis media	0.000	0.965	0.035
H65.2 Chronic serous otitis media	0.000	0.965	0.034
H65.3 Chronic mucoid otitis media	0.000	0.966	0.034
H66.4 Suppurative otitis media, unspecified	0.000	0.966	0.034
H70.2 Petrositis	0.000	0.966	0.034
H68.1 Obstruction of Eustachian tube	0.000	0.966	0.034
H68.0 Eustachian salpingitis	0.000	0.968	0.032
H66.0 Acute suppurative otitis media	0.000	0.968	0.031
H70.0 Acute mastoiditis	0.000	0.969	0.031
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.969	0.031
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.969	0.030
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.969	0.030
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.969	0.030
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.969	0.030
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.969	0.030
H69 Other disorders of Eustachian tube	0.000	0.971	0.029
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.973	0.027
H60 Otitis externa	0.000	0.973	0.027
H72 Perforation of tympanic membrane	0.000	0.974	0.026
H60.1 Cellulitis of external ear	0.000	0.974	0.026
H60.3 Other infective otitis externa	0.000	0.975	0.025
H60.0 Abscess of external ear	0.000	0.975	0.025
H60-H62 Diseases of external ear	0.000	0.976	0.024
Chapter VIII Diseases of the ear and mastoid process	0.000	0.976	0.024
Z50.8 Care involving use of rehabilitation procedures	0.000	0.976	0.024
Z50 Care involving use of rehabilitation procedures	0.000	0.976	0.024
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.977	0.023
Z50.2 Alcohol rehabilitation	0.000	0.977	0.023
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.978	0.021
H60.4 Cholesteatoma of external ear	0.000	0.978	0.021
H69.0 Patulous Eustachian tube	0.000	0.979	0.021
H60.2 Malignant otitis externa	0.000	0.979	0.020
F52.2 Failure of genital response	0.020	0.980	0.000
H60.8 Other otitis externa	0.000	0.981	0.019
E83.3 Disorders of phosphorus metabolism	0.000	0.981	0.019
E83.4 Disorders of magnesium metabolism	0.000	0.981	0.019
H72.2 Other marginal perforations of tympanic membrane	0.000	0.982	0.018
H74.0 Tympanosclerosis	0.000	0.982	0.017
Z50.3 Drug rehabilitation	0.000	0.982	0.018
H62 Disorders of external ear in diseases classified elsewhere	0.000	0.982	0.018
H60.9 Otitis externa, unspecified	0.000	0.982	0.018
H60.5 Acute otitis externa, non-infective	0.000	0.983	0.017
Z50.6 Orthoptic training	0.000	0.983	0.017
E83 Disorders of mineral metabolism	0.000	0.983	0.017
Z50.4 Psychotherapy, not elsewhere classified	0.000	0.983	0.017
H02.6 Xanthelasma of eyelid	0.000	0.983	0.017
H69.8 Other specified disorders of Eustachian tube	0.000	0.984	0.016
H72.1 Attic perforation of tympanic membrane	0.000	0.984	0.016
H69.9 Eustachian tube disorder, unspecified	0.000	0.984	0.016
E83.5 Disorders of calcium metabolism	0.000	0.985	0.015
Z50.0 Cardiac rehabilitation	0.000	0.986	0.014
Q54.9 Hypospadias, unspecified	0.014	0.986	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.000	0.987	0.013
H62.4 Otitis externa in other diseases classified elsewhere	0.000	0.987	0.013
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.000	0.987	0.013
H62.2 Otitis externa in mycoses	0.000	0.987	0.013
H62.1 Otitis externa in viral diseases classified elsewhere	0.000	0.987	0.013
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.000	0.987	0.013
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.987	0.012
E83.8 Other disorders of mineral metabolism	0.000	0.987	0.012
E83.2 Disorders of zinc metabolism	0.000	0.987	0.012
E83.0 Disorders of copper metabolism	0.000	0.987	0.012
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.012	0.988	0.000
H72.0 Central perforation of tympanic membrane	0.000	0.988	0.012
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.989	0.011
F52 Sexual dysfunction, not caused by organic disorder or disease	0.011	0.989	0.000
R82.9 Other and unspecified abnormal finding in urine	0.011	0.989	0.000
Q54 Hypospadias	0.011	0.989	0.000
I81 Portal vein thrombosis	0.011	0.989	0.000
H80-H83 Diseases of inner ear	0.000	0.989	0.011
Q54.0 Hypospadias, balanic	0.011	0.989	0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.000	0.990	0.010
E10.3 With ophthalmic complications	0.010	0.990	0.000
H61 Other disorders of external ear	0.000	0.990	0.010
H72.8 Other perforations of tympanic membrane	0.000	0.990	0.010
I82 Other venous embolism and thrombosis	0.010	0.990	0.000
D47.1 Chronic myeloproliferative disease	0.000	0.991	0.009
H66.9 Otitis media, unspecified	0.000	0.991	0.009
E87.6 Hypokalaemia	0.000	0.991	0.009
Q54.8 Other hypospadias	0.009	0.991	0.000
I88 Nonspecific lymphadenitis	0.009	0.991	0.000
H81.0 Meniere's disease	0.000	0.991	0.009
S01.8 Open wound of other parts of head	0.009	0.991	0.000
E83.1 Disorders of iron metabolism	0.000	0.991	0.009
H61.1 Non-infective disorders of pinna	0.000	0.991	0.009
F52.0 Lack or loss of sexual desire	0.008	0.991	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.008	0.992	0.000
H81 Disorders of vestibular function	0.000	0.992	0.008
D47.4 Osteomyelofibrosis	0.000	0.992	0.008
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.008	0.992	0.000
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.008	0.992	0.000
F52.7 Excessive sexual drive	0.008	0.992	0.000
F52.6 Nonorganic dyspareunia	0.008	0.992	0.000
F52.5 Nonorganic vaginismus	0.008	0.992	0.000
F52.4 Premature ejaculation	0.008	0.992	0.000
F52.3 Orgasmic dysfunction	0.008	0.992	0.000
F52.1 Sexual aversion and lack of sexual enjoyment	0.008	0.992	0.000
I82.0 Budd-Chiari syndrome	0.008	0.992	0.000
Q54.4 Congenital chordee	0.008	0.992	0.000
Q54.3 Hypospadias, perineal	0.008	0.992	0.000
Q54.2 Hypospadias, penoscrotal	0.008	0.992	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.992	0.008
H82 Vertiginous syndromes in diseases classified elsewhere	0.000	0.992	0.008
H61.3 Acquired stenosis of external ear canal	0.000	0.992	0.008
I82.3 Embolism and thrombosis of renal vein	0.007	0.992	0.000
I82.1 Thrombophlebitis migrans	0.007	0.993	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.993	0.007
H81.8 Other disorders of vestibular function	0.000	0.993	0.007
Q54.1 Hypospadias, penile	0.007	0.993	0.000
H61.8 Other specified disorders of external ear	0.000	0.993	0.007
I82.9 Embolism and thrombosis of unspecified vein	0.007	0.993	0.000
I82.2 Embolism and thrombosis of vena cava	0.007	0.993	0.000
I82.8 Embolism and thrombosis of other specified veins	0.007	0.993	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.007	0.993	0.000
R82 Other abnormal findings in urine	0.007	0.993	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.006	0.993	0.000
I88.0 Nonspecific mesenteric lymphadenitis	0.006	0.993	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.006	0.994	0.000
I87 Other disorders of veins	0.006	0.994	0.000
H81.4 Vertigo of central origin	0.000	0.994	0.006
H61.9 Disorder of external ear, unspecified	0.000	0.994	0.006
I88.8 Other nonspecific lymphadenitis	0.006	0.994	0.000
Chapter IX Diseases of the circulatory system	0.006	0.994	0.000
R82.7 Abnormal findings on microbiological examination of urine	0.006	0.994	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.000	0.994	0.006
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.000	0.994	0.006
I86 Varicose veins of other sites	0.006	0.994	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.994	0.006
R82.4 Acetonuria	0.006	0.994	0.000
H81.2 Vestibular neuronitis	0.000	0.994	0.006
I85 Oesophageal varices	0.006	0.994	0.000
H80 Otosclerosis	0.000	0.994	0.005
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.994	0.005
C51-C58 Malignant neoplasms of female genital organs	0.005	0.995	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.995	0.005
H81.3 Other peripheral vertigo	0.000	0.995	0.005
C56 Malignant neoplasm of ovary	0.005	0.995	0.000
D43.2 Brain, unspecified	0.000	0.995	0.005
I00-I02 Acute rheumatic fever	0.005	0.995	0.000
H61.2 Impacted cerumen	0.000	0.995	0.005
I63.8 Other cerebral infarction	0.005	0.995	0.000
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source	0.005	0.995	0.000
R82.3 Haemoglobinuria	0.005	0.995	0.000
R82.2 Biliuria	0.005	0.995	0.000
R82.0 Chyluria	0.005	0.995	0.000
Q38.7 Pharyngeal pouch	0.000	0.995	0.005
C52 Malignant neoplasm of vagina	0.005	0.995	0.000
I87.0 Postphlebitic syndrome	0.005	0.995	0.000
I87.9 Disorder of vein, unspecified	0.005	0.995	0.000
I87.8 Other specified disorders of veins	0.005	0.995	0.000
H81.9 Disorder of vestibular function, unspecified	0.000	0.995	0.005
I87.2 Venous insufficiency (chronic) (peripheral)	0.005	0.995	0.000
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.005	0.995	0.000
C53 Malignant neoplasm of cervix uteri	0.005	0.995	0.000
I86.2 Pelvic varices	0.005	0.995	0.000
D47.2 Monoclonal gammopathy	0.000	0.995	0.005
I63 Cerebral infarction	0.005	0.995	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.000	0.995	0.005
I86.0 Sublingual varices	0.004	0.995	0.000
C57 Malignant neoplasm of other and unspecified female genital organs	0.004	0.995	0.000
H81.1 Benign paroxysmal vertigo	0.000	0.995	0.004
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.004	0.995	0.000
D68.5 Primary Thrombophilia	0.004	0.995	0.000
R82.1 Myoglobinuria	0.004	0.996	0.000
I00 Rheumatic fever without mention of heart involvement	0.004	0.996	0.000
I86.3 Vulval varices	0.004	0.996	0.000
G30.9 Alzheimer's disease, unspecified	0.000	0.996	0.004
Z92 Personal history of medical treatment	0.004	0.996	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.004	0.996	0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.000	0.996	0.004
H80.8 Other otosclerosis	0.000	0.996	0.004
H80.2 Cochlear otosclerosis	0.000	0.996	0.004
H80.1 Otosclerosis involving oval window, obliterative	0.000	0.996	0.004
H80.0 Otosclerosis involving oval window, nonobliterative	0.000	0.996	0.004
C53.0 Endocervix	0.004	0.996	0.000
C58 Malignant neoplasm of placenta	0.004	0.996	0.000
I86.4 Gastric varices	0.004	0.996	0.000
G30 Alzheimer's disease	0.000	0.996	0.004
I02 Rheumatic chorea	0.004	0.996	0.000
I01 Rheumatic fever with heart involvement	0.004	0.996	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.004	0.996	0.000
D43.1 Brain, infratentorial	0.000	0.996	0.004
D43.0 Brain, supratentorial	0.000	0.996	0.004
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.000	0.996	0.004
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.004	0.996	0.000
D68.2 Hereditary deficiency of other clotting factors	0.004	0.996	0.000
C57.0 Fallopian tube	0.004	0.996	0.000
C57.8 Overlapping lesion of female genital organs	0.004	0.996	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.004	0.996	0.000
D44.3 Pituitary gland	0.000	0.996	0.004
Z92.5 Personal history of rehabilitation measures	0.004	0.996	0.000
D43.4 Spinal cord	0.000	0.996	0.004
C54 Malignant neoplasm of corpus uteri	0.004	0.996	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.004	0.996	0.000
C53.9 Cervix uteri, unspecified	0.004	0.996	0.000
C53.8 Overlapping lesion of cervix uteri	0.004	0.996	0.000
C53.1 Exocervix	0.004	0.996	0.000
I86.8 Varicose veins of other specified sites	0.004	0.996	0.000
G30.8 Other Alzheimer's disease	0.000	0.996	0.004
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.004	0.996	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.004	0.996	0.000
Z50.5 Speech therapy	0.000	0.996	0.003
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.000	0.996	0.004
D43.9 Central nervous system, unspecified	0.000	0.996	0.003
D43.7 Other parts of central nervous system	0.000	0.996	0.003
D43.3 Cranial nerves	0.000	0.996	0.003
S13.4 Sprain and strain of cervical spine	0.004	0.996	0.000
H83 Other diseases of inner ear	0.000	0.996	0.003
I86.1 Scrotal varices	0.004	0.996	0.000
G30.0 Alzheimer's disease with early onset	0.000	0.996	0.003
C57.7 Other specified female genital organs	0.003	0.996	0.000
C57.4 Uterine adnexa, unspecified	0.003	0.996	0.000
C57.3 Parametrium	0.003	0.996	0.000
C57.2 Round ligament	0.003	0.996	0.000
C57.1 Broad ligament	0.003	0.996	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.004	0.996	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.000	0.997	0.003
B18.1 Chronic viral hepatitis B without delta-agent	0.003	0.997	0.000
Z92.9 Personal history of medical treatment, unspecified	0.003	0.997	0.000
H04.1 Other disorders of lachrymal gland	0.000	0.997	0.003
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.003	0.997	0.000
R82.8 Abnormal findings on cytological and histological examination of urine	0.003	0.997	0.000
C51 Malignant neoplasm of vulva	0.003	0.997	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
Q24.5 Malformation of coronary vessels	0.003	0.997	0.000
Q24 Other congenital malformations of heart	0.003	0.997	0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.003	0.997	0.000
G30.1 Alzheimer's disease with late onset	0.000	0.997	0.003
C57.9 Female genital organ, unspecified	0.003	0.997	0.000
S12.2 Fracture of other specified cervical vertebra	0.003	0.997	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.003	0.997	0.000
D44.4 Craniopharyngeal duct	0.000	0.997	0.003
D44.0 Thyroid gland	0.000	0.997	0.003
I01.9 Acute rheumatic heart disease, unspecified	0.003	0.997	0.000
I01.8 Other acute rheumatic heart disease	0.003	0.997	0.000
I01.2 Acute rheumatic myocarditis	0.003	0.997	0.000
I01.1 Acute rheumatic endocarditis	0.003	0.997	0.000
I01.0 Acute rheumatic pericarditis	0.003	0.997	0.000
I02.9 Rheumatic chorea without heart involvement	0.003	0.997	0.000
I02.0 Rheumatic chorea with heart involvement	0.003	0.997	0.000
F51 Nonorganic sleep disorders	0.003	0.997	0.000
Q50-Q56 Congenital malformations of genital organs	0.003	0.997	0.000
Q24.8 Other specified congenital malformations of heart	0.003	0.997	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.003	0.997	0.000
C54.9 Corpus uteri, unspecified	0.003	0.997	0.000
I85.9 Oesophageal varices without bleeding	0.003	0.997	0.000
G31.0 Circumscribed brain atrophy	0.000	0.997	0.003
H95.1 Other disorders following mastoidectomy	0.000	0.997	0.003
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors	0.003	0.997	0.000
F55 Abuse of non-dependence-producing substances	0.003	0.997	0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere	0.003	0.997	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.003	0.997	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.003	0.997	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.003	0.997	0.000
C54.8 Overlapping lesion of corpus uteri	0.003	0.997	0.000
C54.3 Fundus uteri	0.003	0.997	0.000
C54.2 Myometrium	0.003	0.997	0.000
C54.0 Isthmus uteri	0.003	0.997	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.003	0.997	0.000
D44.8 Pluriglandular involvement	0.000	0.997	0.003
D44.9 Endocrine gland, unspecified	0.000	0.997	0.003
D44.5 Pineal gland	0.000	0.997	0.003
D44.2 Parathyroid gland	0.000	0.997	0.003
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.003	0.997	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.000	0.997	0.003
H83.3 Noise effects on inner ear	0.000	0.997	0.003
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.003	0.997	0.000
H83.2 Labyrinthine dysfunction	0.000	0.997	0.003
H83.1 Labyrinthine fistula	0.000	0.997	0.003
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.000	0.997	0.003
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.000	0.997	0.003
H90-H95 Other disorders of ear	0.000	0.997	0.003
F53.0 Mild mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.003	0.997	0.000
I85.0 Oesophageal varices with bleeding	0.003	0.997	0.000
Q24.6 Congenital heart block	0.003	0.997	0.000
D44.7 Aortic body and other paraganglia	0.000	0.997	0.003
O47.9 False labour, unspecified	0.003	0.997	0.000
T45.0 Antiallergic and antiemetic drugs	0.003	0.997	0.000
D38.1 Trachea, bronchus and lung	0.000	0.997	0.003
K05.6 Periodontal disease, unspecified	0.003	0.997	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.001	0.997	0.002
Q24.0 Dextrocardia	0.003	0.997	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.003	0.997	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.997	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.997	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.003	0.997	0.000
T44.0 Anticholinesterase agents	0.003	0.997	0.000
D44.6 Carotid body	0.000	0.997	0.003
G31.2 Degeneration of nervous system due to alcohol	0.000	0.997	0.003
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.000	0.997	0.003
F51.0 Nonorganic insomnia	0.003	0.997	0.000
H83.9 Disease of inner ear, unspecified	0.000	0.997	0.003
R81 Glycosuria	0.003	0.997	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.003	0.997	0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
F51.4 Sleep terrors [night terrors]	0.002	0.997	0.000
G30-G32 Other degenerative diseases of the nervous system	0.000	0.997	0.003
Q21.0 Ventricular septal defect	0.003	0.997	0.000
T36.0 Penicillins	0.003	0.997	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.997	0.003
Q52 Other congenital malformations of female genitalia	0.003	0.997	0.000
C51.8 Overlapping lesion of vulva	0.002	0.997	0.000
C51.2 Clitoris	0.002	0.997	0.000
C51.1 Labium minus	0.002	0.997	0.000
D41.0 Kidney	0.000	0.997	0.003
Q24.4 Congenital subaortic stenosis	0.002	0.997	0.000
Q24.3 Pulmonary infundibular stenosis	0.002	0.997	0.000
Q24.2 Cor triatriatum	0.002	0.997	0.000
Q24.1 Levocardia	0.002	0.997	0.000
C51.0 Labium majus	0.002	0.997	0.000
F53.9 Puerperal mental disorder, unspecified	0.002	0.997	0.000
F53.8 Other mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.002	0.997	0.000
F53.1 Severe mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.002	0.997	0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.000	0.997	0.003
Z92.4 Personal history of major surgery, not elsewhere classified	0.003	0.997	0.000
Q55 Other congenital malformations of male genital organs	0.002	0.997	0.000
I12.9 Hypertensive renal disease without renal failure	0.003	0.997	0.000
S12 Fracture of neck	0.003	0.997	0.000
S12.21 Fracture of other specified cervical vertebra (open)	0.002	0.997	0.000
H61.0 Perichondritis of external ear	0.000	0.997	0.002
D46 Myelodysplastic syndromes	0.000	0.997	0.003
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.002	0.997	0.000
D44.1 Adrenal gland	0.000	0.997	0.002
D48.1 Connective and other soft tissue	0.000	0.997	0.003
O90.8 Other complications of the puerperium, not elsewhere classified	0.003	0.997	0.000
F51.9 Nonorganic sleep disorder, unspecified	0.002	0.997	0.000
F51.8 Other nonorganic sleep disorders	0.002	0.997	0.000
F51.2 Nonorganic disorder of the sleep-wake schedule	0.002	0.997	0.000
F51.1 Nonorganic hypersomnia	0.002	0.997	0.000
S13.1 Dislocation of cervical vertebra	0.002	0.997	0.000
H34.2 Other retinal artery occlusions	0.002	0.997	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.002	0.997	0.000
O90.1 Disruption of perineal obstetric wound	0.002	0.998	0.000
U89.8 Agent resistant to other single specified antibiotic	0.000	0.998	0.002
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.000	0.998	0.002
I06.0 Rheumatic aortic stenosis	0.002	0.998	0.000
I05-I09 Chronic rheumatic heart diseases	0.002	0.998	0.000
S12.7 Multiple fractures of cervical spine	0.002	0.998	0.000
Q21 Congenital malformations of cardiac septa	0.002	0.998	0.000
I06 Rheumatic aortic valve diseases	0.002	0.998	0.000
D40.1 Testis	0.000	0.998	0.002
Q38.1 Ankyloglossia	0.000	0.998	0.002
R45.2 Unhappiness	0.000	0.998	0.002
S13.5 Sprain and strain of thyroid region	0.002	0.998	0.000
S13.3 Multiple dislocations of neck	0.002	0.998	0.000
S13.2 Dislocation of other and unspecified parts of neck	0.002	0.998	0.000
S13.0 Traumatic rupture of cervical intervertebral disk	0.002	0.998	0.000
T82.1 Mechanical complication of cardiac electronic device	0.002	0.998	0.000
D38.5 Other respiratory organs	0.000	0.998	0.002
F51.3 Sleepwalking [somnambulism]	0.002	0.998	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.002	0.998	0.000
C18.1 Appendix	0.002	0.998	0.000
D38.6 Respiratory organ, unspecified	0.000	0.998	0.002
D38.4 Thymus	0.000	0.998	0.002
D38.2 Pleura	0.000	0.998	0.002
D40.0 Prostate	0.000	0.998	0.002
H83.8 Other specified diseases of inner ear	0.000	0.998	0.002
H95.8 Other postprocedural disorders of ear and mastoid process	0.000	0.998	0.002
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.000	0.998	0.002
Q52.4 Other congenital malformations of vagina	0.002	0.998	0.000
D40.9 Male genital organ, unspecified	0.000	0.998	0.002
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.998	0.002
H94 Other disorders of ear in diseases classified elsewhere	0.000	0.998	0.002
M96.0 Pseudarthrosis after fusion or arthrodesis	0.000	0.998	0.002
N97.9 Female infertility, unspecified	0.000	0.998	0.002
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.002	0.998	0.000
D40.7 Other male genital organs	0.000	0.998	0.002
Q38.8 Other congenital malformations of pharynx	0.001	0.998	0.002
Q38.5 Congenital malformations of palate, not elsewhere classified	0.001	0.998	0.002
Q38.4 Congenital malformations of salivary glands and ducts	0.001	0.998	0.002
Q38.3 Other congenital malformations of tongue	0.001	0.998	0.002
Q38.2 Macroglossia	0.001	0.998	0.002
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.000	0.998	0.002
I09 Other rheumatic heart diseases	0.002	0.998	0.000
Q52.5 Fusion of labia	0.002	0.998	0.000
D42.9 Meninges, unspecified	0.000	0.998	0.002
D42.1 Spinal meninges	0.000	0.998	0.002
D42.0 Cerebral meninges	0.000	0.998	0.002
D48.7 Other specified sites	0.000	0.998	0.002
F51.5 Nightmares	0.002	0.998	0.000
Q83.1 Accessory breast	0.002	0.998	0.000
E87.5 Hyperkalaemia	0.000	0.998	0.002
G44.2 Tension-type headache	0.002	0.998	0.000
H34.8 Other retinal vascular occlusions	0.002	0.998	0.000
Q38.6 Other congenital malformations of mouth	0.001	0.998	0.002
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.000	0.998	0.002
Q55.2 Other congenital malformations of testis and scrotum	0.002	0.998	0.000
D38.3 Mediastinum	0.000	0.998	0.002
I09.9 Rheumatic heart disease, unspecified	0.002	0.998	0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.000	0.998	0.002
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.998	0.002
N32.3 Diverticulum of bladder	0.002	0.998	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.002	0.998	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.002	0.998	0.000
Q52.7 Other congenital malformations of vulva	0.002	0.998	0.000
Q52.6 Congenital malformation of clitoris	0.002	0.998	0.000
Q52.3 Imperforate hymen	0.002	0.998	0.000
Q52.2 Congenital rectovaginal fistula	0.002	0.998	0.000
Q52.0 Congenital absence of vagina	0.002	0.998	0.000
R74.8 Abnormal levels of other serum enzymes	0.000	0.998	0.002
S12.1 Fracture of second cervical vertebra	0.002	0.998	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.000	0.998	0.002
C54.1 Endometrium	0.002	0.998	0.000
I87.1 Compression of vein	0.002	0.998	0.001
D46.1 Refractory anaemia with sideroblasts	0.000	0.998	0.002
Q21.8 Other congenital malformations of cardiac septa	0.002	0.998	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.001	0.998	0.001
S52.80 Fracture of other parts of forearm (closed)	0.002	0.998	0.000
Z92.0 Personal history of contraception	0.002	0.998	0.000
O82.0 Delivery by elective Caesarean section	0.000	0.998	0.002
Q55.9 Congenital malformation of male genital organ, unspecified	0.002	0.998	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.002	0.998	0.000
Q55.6 Other congenital malformations of penis	0.002	0.998	0.000
Q55.5 Congenital absence and aplasia of penis	0.002	0.998	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.002	0.998	0.000
Q55.3 Atresia of vas deferens	0.002	0.998	0.000
Q55.1 Hypoplasia of testis and scrotum	0.002	0.998	0.000
Q55.0 Absence and aplasia of testis	0.002	0.998	0.000
S12.8 Fracture of other parts of neck	0.002	0.998	0.000
W55.8 Other specified place	0.002	0.998	0.000
I83 Varicose veins of lower extremities	0.002	0.998	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.000	0.998	0.002
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.000	0.998	0.002
D46.5 Refractory anaemia with multi-lineage dysplasia	0.000	0.998	0.002
D46.3 Refractory anaemia with excess of blasts with transformation	0.000	0.998	0.002
D46.0 Refractory anaemia without sideroblasts, so stated	0.000	0.998	0.002
G82.1 Spastic paraplegia	0.000	0.998	0.002
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.002	0.998	0.000
T36 Poisoning by systemic antibiotics	0.002	0.998	0.000
D41.2 Ureter	0.000	0.998	0.002
D46.2 Refractory anaemia with excess of blasts	0.000	0.998	0.002
G70.9 Myoneural disorder, unspecified	0.002	0.998	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.002	0.998	0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.998	0.002
Q52.1 Doubling of vagina	0.002	0.998	0.000
I10-I15 Hypertensive diseases	0.002	0.998	0.000
Q56.4 Indeterminate sex, unspecified	0.002	0.998	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.002	0.998	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.002	0.998	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.002	0.998	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.002	0.998	0.000
Q89.2 Congenital malformations of other endocrine glands	0.002	0.998	0.000
V89.9 Person injured in unspecified vehicle accident	0.000	0.998	0.002
D66 Hereditary factor VIII deficiency	0.000	0.998	0.002
O90 Complications of the puerperium, not elsewhere classified	0.002	0.998	0.000
M47.86 Other spondylosis (Lumbar region)	0.000	0.998	0.002
D41.9 Urinary organ, unspecified	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations