TreeWAS – Variant ID: rs4458523

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E11.9 Without complications	1.000	0.000	0.000
E11 Non-insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
E14 Unspecified diabetes mellitus	1.000	0.000	0.000
E11.3 With ophthalmic complications	0.997	0.003	0.000
E14.9 Without complications	0.996	0.004	0.000
E14.3 With ophthalmic complications	0.990	0.010	0.000
E10.1 With ketoacidosis	0.964	0.036	0.000
E11.1 With ketoacidosis	0.940	0.060	0.000
E10.8 With unspecified complications	0.933	0.067	0.000
E10.5 With peripheral circulatory complications	0.907	0.093	0.000
E11.2 With renal complications	0.905	0.095	0.000
E10.3 With ophthalmic complications	0.896	0.104	0.000
E10.2 With renal complications	0.885	0.115	0.000
E10.0 With coma	0.871	0.129	0.000
E10.6 With other specified complications	0.847	0.153	0.000
E14.6 With other specified complications	0.811	0.189	0.000
E14.4 With neurological complications	0.796	0.204	0.000
E13 Other specified diabetes mellitus	0.792	0.208	0.000
E11.6 With other specified complications	0.788	0.212	0.000
E14.8 With unspecified complications	0.769	0.231	0.000
E14.5 With peripheral circulatory complications	0.740	0.260	0.000
E11.5 With peripheral circulatory complications	0.733	0.267	0.000
E10.7 With multiple complications	0.730	0.270	0.000
E14.0 With coma	0.727	0.273	0.000
E14.1 With ketoacidosis	0.719	0.281	0.000
E11.7 With multiple complications	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
E14.7 With multiple complications	0.717	0.283	0.000
E14.2 Withrenal complications	0.698	0.302	0.000
E11.8 With unspecified complications	0.663	0.337	0.000
E11.4 With neurological complications	0.646	0.354	0.000
H36.0 Diabetic retinopathy	0.639	0.361	0.000
E13.3 With ophthalmic complications	0.616	0.384	0.000
E13.9 Without complications	0.601	0.399	0.000
E13.8 With unspecified complications	0.567	0.432	0.000
E13.7 With multiple complications	0.567	0.432	0.000
E13.6 With other specified complications	0.567	0.432	0.000
E13.5 With peripheral circulatory complications	0.567	0.432	0.000
E13.4 With neurological complications	0.567	0.432	0.000
E13.2 With renal complications	0.567	0.432	0.000
E13.1 With ketoacidosis	0.567	0.432	0.000
E13.0 With coma	0.567	0.432	0.000
E11.0 With coma	0.566	0.434	0.000
E12.9 Without complications	0.514	0.486	0.000
E12.8 With unspecified complications	0.514	0.486	0.000
E12.7 With multiple complications	0.514	0.486	0.000
E12.6 With other specified complications	0.514	0.486	0.000
E12.5 With peripheral circulatory complications	0.514	0.486	0.000
E12.4 With neurological complications	0.514	0.486	0.000
E12.3 With ophthalmic complications	0.514	0.486	0.000
E12.2 With renal complications	0.514	0.486	0.000
E12.1 With ketoacidosis	0.514	0.486	0.000
E12.0 With coma	0.514	0.486	0.000
E10.4 With neurological complications	0.505	0.495	0.000
H36 Retinal disorders in diseases classified elsewhere	0.297	0.703	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.213	0.787	0.000
H30-H36 Disorders of choroid and retina	0.051	0.949	0.000
H34 Retinal vascular occlusions	0.050	0.950	0.000
H34.8 Other retinal vascular occlusions	0.043	0.957	0.000
H34.1 Central retinal artery occlusion	0.042	0.958	0.000
H34.2 Other retinal artery occlusions	0.041	0.959	0.000
H34.9 Retinal vascular occlusion, unspecified	0.038	0.962	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.037	0.963	0.000
H34.0 Transient retinal artery occlusion	0.036	0.964	0.000
H30 Chorioretinal inflammation	0.033	0.967	0.000
H31 Other disorders of choroid	0.030	0.969	0.000
I42.9 Cardiomyopathy, unspecified	0.030	0.970	0.000
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.027	0.973	0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.027	0.973	0.000
H30.2 Posterior cyclitis	0.025	0.975	0.000
H30.8 Other chorioretinal inflammations	0.024	0.976	0.000
H30.1 Disseminated chorioretinal inflammation	0.024	0.976	0.000
H30.0 Focal chorioretinal inflammation	0.024	0.976	0.000
H31.8 Other specified disorders of choroid	0.024	0.976	0.000
H31.1 Choroidal degeneration	0.023	0.977	0.000
H31.4 Choroidal detachment	0.022	0.978	0.000
H31.2 Hereditary choroidal dystrophy	0.022	0.978	0.000
H31.3 Choroidal haemorrhage and rupture	0.021	0.978	0.000
H31.9 Disorder of choroid, unspecified	0.020	0.980	0.000
H30.9 Chorioretinal inflammation, unspecified	0.018	0.981	0.000
C71 Malignant neoplasm of brain	0.018	0.982	0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.018	0.982	0.000
C71.9 Brain, unspecified	0.018	0.982	0.000
C71.1 Frontal lobe	0.018	0.982	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.017	0.983	0.000
C71.2 Temporal lobe	0.016	0.984	0.000
C71.8 Overlapping lesion of brain	0.016	0.984	0.000
C71.4 Occipital lobe	0.015	0.985	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.014	0.986	0.000
H31.0 Chorioretinal scars	0.013	0.986	0.000
C71.3 Parietal lobe	0.013	0.986	0.000
C71.6 Cerebellum	0.013	0.987	0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.000	0.987	0.013
C71.7 Brain stem	0.012	0.987	0.000
C71.0 Cerebrum, except lobes and ventricles	0.012	0.987	0.000
C71.5 Cerebral ventricle	0.012	0.988	0.000
E16 Other disorders of pancreatic internal secretion	0.012	0.988	0.000
E20-E35 Disorders of other endocrine glands	0.012	0.988	0.000
N60.8 Other benign mammary dysplasias	0.012	0.988	0.000
H26.8 Other specified cataract	0.000	0.989	0.011
E16.2 Hypoglycaemia, unspecified	0.011	0.989	0.000
E15 Nondiabetic hypoglycaemic coma	0.010	0.990	0.000
E34 Other endocrine disorders	0.010	0.990	0.000
E40-E46 Malnutrition	0.010	0.990	0.000
E32 Diseases of thymus	0.010	0.990	0.000
E16.1 Other hypoglycaemia	0.010	0.990	0.000
E25 Adrenogenital disorders	0.009	0.991	0.000
E65-E68 Obesity and other hyperalimentation	0.009	0.991	0.000
E26 Hyperaldosteronism	0.009	0.991	0.000
E23 Hypofunction and other disorders of pituitary gland	0.009	0.991	0.000
E34.0 Carcinoid syndrome	0.009	0.991	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.009	0.991	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.009	0.991	0.000
E16.4 Abnormal secretion of gastrin	0.009	0.991	0.000
E16.3 Increased secretion of glucagon	0.009	0.991	0.000
G31.8 Other specified degenerative diseases of nervous system	0.000	0.991	0.009
H33 Retinal detachments and breaks	0.009	0.991	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.009	0.991	0.000
E30 Disorders of puberty, not elsewhere classified	0.009	0.991	0.000
E29 Testicular dysfunction	0.009	0.991	0.000
E31 Polyglandular dysfunction	0.009	0.991	0.000
E22 Hyperfunction of pituitary gland	0.009	0.991	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.008	0.991	0.000
E34.9 Endocrine disorder, unspecified	0.008	0.992	0.000
E24 Cushing's syndrome	0.008	0.992	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.000	0.992	0.008
E32.8 Other diseases of thymus	0.008	0.992	0.000
E27 Other disorders of adrenal gland	0.008	0.992	0.000
H33.1 Retinoschisis and retinal cysts	0.008	0.992	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.000	0.992	0.008
E65 Localised adiposity	0.008	0.992	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.008	0.992	0.000
E20 Hypoparathyroidism	0.008	0.992	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.008	0.992	0.000
R94.5 Abnormal results of liver function studies	0.008	0.992	0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.008	0.992	0.000
E34.5 Androgen resistance syndrome	0.007	0.992	0.000
E34.4 Constitutional tall stature	0.007	0.992	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.007	0.992	0.000
E34.1 Other hypersecretion of intestinal hormones	0.007	0.992	0.000
L27 Dermatitis due to substances taken internally	0.000	0.992	0.008
E32.9 Disease of thymus, unspecified	0.007	0.992	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.007	0.993	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.007	0.993	0.000
E45 Retarded development following protein-energy malnutrition	0.007	0.993	0.000
E43 Unspecified severe protein-energy malnutrition	0.007	0.993	0.000
E42 Marasmic kwashiorkor	0.007	0.993	0.000
E41 Nutritional marasmus	0.007	0.993	0.000
E40 Kwashiorkor	0.007	0.993	0.000
E26.9 Hyperaldosteronism, unspecified	0.007	0.993	0.000
E32.1 Abscess of thymus	0.007	0.993	0.000
E32.0 Persistent hyperplasia of thymus	0.007	0.993	0.000
E34.3 Short stature, not elsewhere classified	0.007	0.993	0.000
E22.1 Hyperprolactinaemia	0.007	0.993	0.000
E25.9 Adrenogenital disorder, unspecified	0.007	0.993	0.000
E25.8 Other adrenogenital disorders	0.007	0.993	0.000
E67 Other hyperalimentation	0.007	0.993	0.000
E68 Sequelae of hyperalimentation	0.007	0.993	0.000
E22.0 Acromegaly and pituitary gigantism	0.007	0.993	0.000
E34.8 Other specified endocrine disorders	0.007	0.993	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.007	0.993	0.000
E29.1 Testicular hypofunction	0.007	0.993	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.007	0.993	0.000
E26.8 Other hyperaldosteronism	0.007	0.993	0.000
E26.1 Secondary hyperaldosteronism	0.007	0.993	0.000
E23.1 Drug-induced hypopituitarism	0.007	0.993	0.000
E23.7 Disorder of pituitary gland, unspecified	0.007	0.993	0.000
E23.0 Hypopituitarism	0.007	0.993	0.000
E23.2 Diabetes insipidus	0.007	0.993	0.000
E28 Ovarian dysfunction	0.007	0.993	0.000
E24.9 Cushing's syndrome, unspecified	0.007	0.993	0.000
E30.9 Disorder of puberty, unspecified	0.006	0.993	0.000
E30.8 Other disorders of puberty	0.006	0.993	0.000
E30.1 Precocious puberty	0.006	0.993	0.000
E30.0 Delayed puberty	0.006	0.993	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.006	0.993	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.006	0.993	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.006	0.993	0.000
E24.0 Pituitary-dependent Cushing's disease	0.006	0.993	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.006	0.993	0.000
E29.8 Other testicular dysfunction	0.006	0.993	0.000
E29.0 Testicular hyperfunction	0.006	0.993	0.000
E31.9 Polyglandular dysfunction, unspecified	0.006	0.993	0.000
E31.8 Other polyglandular dysfunction	0.006	0.993	0.000
E31.1 Polyglandular hyperfunction	0.006	0.993	0.000
E26.0 Primary hyperaldosteronism	0.006	0.993	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.006	0.994	0.000
E22.8 Other hyperfunction of pituitary gland	0.006	0.994	0.000
E27.2 Addisonian crisis	0.006	0.994	0.000
E31.0 Autoimmune polyglandular failure	0.006	0.994	0.000
E23.6 Other disorders of pituitary gland	0.006	0.994	0.000
L27.2 Dermatitis due to ingested food	0.000	0.994	0.006
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.006	0.994	0.000
E24.3 Ectopic ACTH syndrome	0.006	0.994	0.000
E24.1 Nelson's syndrome	0.006	0.994	0.000
E27.5 Adrenomedullary hyperfunction	0.006	0.994	0.000
E27.0 Other adrenocortical overactivity	0.006	0.994	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.006	0.994	0.000
E29.9 Testicular dysfunction, unspecified	0.006	0.994	0.000
G31.0 Circumscribed brain atrophy	0.000	0.994	0.006
C70 Malignant neoplasm of meninges	0.006	0.994	0.000
C69 Malignant neoplasm of eye and adnexa	0.006	0.994	0.000
E20.8 Other hypoparathyroidism	0.006	0.994	0.000
E20.1 Pseudohypoparathyroidism	0.006	0.994	0.000
E20.0 Idiopathic hypoparathyroidism	0.006	0.994	0.000
E24.8 Other Cushing's syndrome	0.006	0.994	0.000
H33.0 Retinal detachment with retinal break	0.006	0.994	0.000
L27.9 Dermatitis due to unspecified substance taken internally	0.000	0.994	0.006
L27.8 Dermatitis due to other substances taken internally	0.000	0.994	0.006
E24.2 Drug-induced Cushing's syndrome	0.006	0.994	0.000
M24.02 Loose body in joint (Upper arm)	0.006	0.994	0.000
E44.1 Mild protein-energy malnutrition	0.005	0.994	0.000
E44.0 Moderate protein-energy malnutrition	0.005	0.994	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.005	0.994	0.000
N60.3 Fibrosclerosis of breast	0.006	0.994	0.000
E27.8 Other specified disorders of adrenal gland	0.005	0.995	0.000
E27.9 Disorder of adrenal gland, unspecified	0.005	0.995	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.995	0.005
E67.8 Other specified hyperalimentation	0.005	0.995	0.000
E67.3 Hypervitaminosis D	0.005	0.995	0.000
E67.2 Megavitamin-B6 syndrome	0.005	0.995	0.000
E67.1 Hypercarotenaemia	0.005	0.995	0.000
E67.0 Hypervitaminosis A	0.005	0.995	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.995	0.005
M24.01 Loose body in joint (Shoulder region)	0.005	0.995	0.000
E21.0 Primary hyperparathyroidism	0.005	0.995	0.000
C69.9 Eye, unspecified	0.005	0.995	0.000
L98.8 Other specified disorders of skin and subcutaneous tissue	0.000	0.995	0.005
E46 Unspecified protein-energy malnutrition	0.005	0.995	0.000
E28.9 Ovarian dysfunction, unspecified	0.005	0.995	0.000
E28.8 Other ovarian dysfunction	0.005	0.995	0.000
E28.1 Androgen excess	0.005	0.995	0.000
E28.0 Oestrogen excess	0.005	0.995	0.000
H73.8 Other specified disorders of tympanic membrane	0.005	0.995	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.005	0.995	0.000
E21.4 Other specified disorders of parathyroid gland	0.005	0.995	0.000
N60 Benign mammary dysplasia	0.005	0.995	0.000
N60.1 Diffuse cystic mastopathy	0.005	0.995	0.000
C72.0 Spinal cord	0.005	0.995	0.000
R94 Abnormal results of function studies	0.005	0.995	0.000
C69.3 Choroid	0.005	0.995	0.000
C69.4 Ciliary body	0.005	0.995	0.000
E20.9 Hypoparathyroidism, unspecified	0.004	0.995	0.000
C72.9 Central nervous system, unspecified	0.004	0.995	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.004	0.995	0.000
C72.5 Other and unspecified cranial nerves	0.004	0.995	0.000
C72.4 Acoustic nerve	0.004	0.995	0.000
C72.3 Optic nerve	0.004	0.995	0.000
C72.2 Olfactory nerve	0.004	0.995	0.000
C72.1 Cauda equina	0.004	0.995	0.000
E21.2 Other hyperparathyroidism	0.004	0.995	0.000
E27.1 Primary adrenocortical insufficiency	0.005	0.995	0.000
M24.0 Loose body in joint	0.005	0.995	0.000
C70.9 Meninges, unspecified	0.004	0.995	0.000
C70.1 Spinal meninges	0.004	0.995	0.000
R94.2 Abnormal results of pulmonary function studies	0.005	0.995	0.000
H73 Other disorders of tympanic membrane	0.005	0.995	0.000
C70.0 Cerebral meninges	0.004	0.995	0.000
H33.4 Traction detachment of retina	0.004	0.995	0.000
C69.8 Overlapping lesion of eye and adnexa	0.004	0.995	0.000
C69.5 Lachrymal gland and duct	0.004	0.995	0.000
C69.1 Cornea	0.004	0.995	0.000
Z90.2 Acquired absence of lung [part of]	0.005	0.995	0.000
J39.8 Other specified diseases of upper respiratory tract	0.000	0.996	0.004
D75.1 Secondary polycythaemia	0.004	0.996	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.004	0.996	0.000
R94.0 Abnormal results of function studies of central nervous system	0.004	0.996	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.004	0.996	0.000
H65-H75 Diseases of middle ear and mastoid	0.004	0.996	0.000
C69.2 Retina	0.004	0.996	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.004	0.996	0.000
E28.3 Primary ovarian failure	0.004	0.996	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.996	0.004
C69.0 Conjunctiva	0.004	0.996	0.000
R94.4 Abnormal results of kidney function studies	0.004	0.996	0.000
H33.2 Serous retinal detachment	0.004	0.996	0.000
H71 Cholesteatoma of middle ear	0.004	0.996	0.000
H74 Other disorders of middle ear and mastoid	0.004	0.996	0.000
E21.3 Hyperparathyroidism, unspecified	0.004	0.996	0.000
E28.2 Polycystic ovarian syndrome	0.004	0.996	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.004	0.996	0.000
C69.6 Orbit	0.004	0.996	0.000
H72.1 Attic perforation of tympanic membrane	0.004	0.996	0.000
H72 Perforation of tympanic membrane	0.004	0.996	0.000
R94.6 Abnormal results of thyroid function studies	0.004	0.996	0.000
M24.06 Loose body in joint-Lower leg	0.004	0.996	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.000	0.996	0.004
M24.05 Loose body in joint (Pelvic region and thigh)	0.004	0.996	0.000
H66.3 Other chronic suppurative otitis media	0.004	0.996	0.000
K72.9 Hepatic failure, unspecified	0.004	0.996	0.000
N81.5 Vaginal enterocele	0.000	0.996	0.004
N70.1 Chronic salpingitis and oophoritis	0.000	0.996	0.004
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.003	0.996	0.000
M24.04 Loose body in joint (Hand)	0.003	0.996	0.000
M24.09 Loose body in joint (Site unspecified)	0.003	0.996	0.000
M24.08 Loose body in joint (Other)	0.003	0.996	0.000
M24.03 Loose body in joint (Forearm)	0.003	0.996	0.000
M24.00 Loose body in joint (Multiple sites)	0.003	0.996	0.000
K75.4 Autoimmune hepatitis	0.004	0.996	0.000
H65.3 Chronic mucoid otitis media	0.004	0.996	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.003	0.996	0.000
N60.9 Benign mammary dysplasia, unspecified	0.003	0.996	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.004	0.996	0.000
H66 Suppurative and unspecified otitis media	0.003	0.996	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.003	0.997	0.000
H70 Mastoiditis and related conditions	0.003	0.997	0.000
R94.8 Abnormal results of function studies of other organs and systems	0.003	0.997	0.000
H33.5 Other retinal detachments	0.003	0.997	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.003	0.997	0.000
M81.4 Drug-induced osteoporosis	0.000	0.997	0.003
E50-E64 Other nutritional deficiencies	0.003	0.997	0.000
K31.5 Obstruction of duodenum	0.000	0.997	0.003
H73.0 Acute myringitis	0.003	0.997	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.997	0.003
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.003	0.997	0.000
H67 Otitis media in diseases classified elsewhere	0.003	0.997	0.000
E00-E07 Disorders of thyroid gland	0.003	0.997	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.000	0.997	0.003
H72.9 Perforation of tympanic membrane, unspecified	0.003	0.997	0.000
H72.2 Other marginal perforations of tympanic membrane	0.003	0.997	0.000
H73.1 Chronic myringitis	0.003	0.997	0.000
H68 Eustachian salpingitis and obstruction	0.003	0.997	0.000
M24.07 Loose body in joint (Ankle and foot)	0.003	0.997	0.000
R94.3 Abnormal results of cardiovascular function studies	0.003	0.997	0.000
V18.1 Passenger injured in nontraffic accident	0.003	0.997	0.000
V18.3 Person injured while boarding or alighting	0.003	0.997	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.000	0.997	0.003
H72.8 Other perforations of tympanic membrane	0.003	0.997	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.003	0.997	0.000
H65 Nonsuppurative otitis media	0.003	0.997	0.000
N60.4 Mammary duct ectasia	0.003	0.997	0.000
R94.7 Abnormal results of other endocrine function studies	0.003	0.997	0.000
H74.1 Adhesive middle ear disease	0.003	0.997	0.000
F22.0 Delusional disorder	0.003	0.997	0.000
H70.0 Acute mastoiditis	0.003	0.997	0.000
H74.0 Tympanosclerosis	0.003	0.997	0.000
H66.9 Otitis media, unspecified	0.003	0.997	0.000
H70.1 Chronic mastoiditis	0.003	0.997	0.000
Q61.2 Polycystic kidney, adult type	0.000	0.997	0.003
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.003	0.997	0.000
V18.9 Unspecified pedal cyclist injured in traffic accident	0.003	0.997	0.000
V18.4 Driver injured in traffic accident	0.003	0.997	0.000
E51 Thiamine deficiency	0.003	0.997	0.000
M79.62 Pain in limb (Upper arm)	0.000	0.997	0.003
E05.8 Other thyrotoxicosis	0.003	0.997	0.000
H70.2 Petrositis	0.003	0.997	0.000
E63 Other nutritional deficiencies	0.002	0.997	0.000
Q61 Cystic kidney disease	0.000	0.997	0.003
M81.48 Drug-induced osteoporosis (Other)	0.000	0.997	0.003
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.000	0.997	0.003
M81.46 Drug-induced osteoporosis (Lower leg)	0.000	0.997	0.003
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.000	0.997	0.003
M81.44 Drug-induced osteoporosis (Hand)	0.000	0.997	0.003
M81.43 Drug-induced osteoporosis (Forearm)	0.000	0.997	0.003
M81.42 Drug-induced osteoporosis (Upper arm)	0.000	0.997	0.003
M81.41 Drug-induced osteoporosis (Shoulder region)	0.000	0.997	0.003
C45.9 Mesothelioma, unspecified	0.003	0.997	0.000
H33.3 Retinal breaks without detachment	0.003	0.997	0.000
M24.54 Contracture of joint (Hand)	0.000	0.997	0.003
H70.9 Mastoiditis, unspecified	0.003	0.997	0.000
H70.8 Other mastoiditis and related conditions	0.003	0.997	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.002	0.997	0.000
E50 Vitamin A deficiency	0.002	0.997	0.000
E60 Dietary zinc deficiency	0.002	0.997	0.000
E59 Dietary selenium deficiency	0.002	0.997	0.000
E52 Niacin deficiency [pellagra]	0.002	0.997	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.003	0.997	0.000
Q61.0 Congenital single renal cyst	0.000	0.997	0.003
V18.5 Passenger injured in traffic accident	0.003	0.997	0.000
Q61.3 Polycystic kidney, unspecified	0.000	0.997	0.003
H66.2 Chronic atticoantral suppurative otitis media	0.002	0.997	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.002	0.997	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.002	0.997	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.002	0.997	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.002	0.997	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.002	0.997	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.003	0.997	0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.003	0.997	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.002	0.997	0.000
E00 Congenital iodine-deficiency syndrome	0.002	0.997	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.003	0.997	0.000
C02.9 Tongue, unspecified	0.000	0.997	0.003
H66.1 Chronic tubotympanic suppurative otitis media	0.002	0.997	0.000
H68.0 Eustachian salpingitis	0.002	0.997	0.000
Q64 Other congenital malformations of urinary system	0.000	0.997	0.003
G61.8 Other inflammatory polyneuropathies	0.000	0.997	0.003
H65.1 Other acute nonsuppurative otitis media	0.002	0.997	0.000
E56 Other vitamin deficiencies	0.002	0.997	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.003	0.997	0.000
M54.49 Lumbago with sciatica (Site unspecified)	0.000	0.997	0.003
H68.1 Obstruction of Eustachian tube	0.002	0.997	0.000
E54 Ascorbic acid deficiency	0.002	0.997	0.000
H53.0 Amblyopia ex anopsia	0.000	0.997	0.002
K75.9 Inflammatory liver disease, unspecified	0.002	0.997	0.000
G31.2 Degeneration of nervous system due to alcohol	0.000	0.998	0.002
Q63 Other congenital malformations of kidney	0.000	0.998	0.002
E51.2 Wernicke's encephalopathy	0.002	0.998	0.000
K75.0 Abscess of liver	0.002	0.998	0.000
H66.4 Suppurative otitis media, unspecified	0.002	0.998	0.000
K75 Other inflammatory liver diseases	0.002	0.998	0.000
E58 Dietary calcium deficiency	0.002	0.998	0.000
H66.0 Acute suppurative otitis media	0.002	0.998	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.002	0.998	0.000
E63.9 Nutritional deficiency, unspecified	0.002	0.998	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.002	0.998	0.000
Y84.2 Radiological procedure and radiotherapy	0.000	0.998	0.002
V18.49 Pedal cyclist injured in noncollision transport accident; driver injured in traffic accident ; during unspecified activity	0.002	0.998	0.000
V18.99 Pedal cyclist injured in noncollision transport accident; unspecified pedal cyclist injured in traffic accident; during unspecified activity	0.002	0.998	0.000
E51.9 Thiamine deficiency, unspecified	0.002	0.998	0.000
E51.8 Other manifestations of thiamine deficiency	0.002	0.998	0.000
E51.1 Beriberi	0.002	0.998	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.998	0.002
S62.51 Fracture of thumb (open)	0.002	0.998	0.000
E63.8 Other specified nutritional deficiencies	0.002	0.998	0.000
E63.1 Imbalance of constituents of food intake	0.002	0.998	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.002	0.998	0.000
E06 Thyroiditis	0.002	0.998	0.000
K26.3 Acute without haemorrhage or perforation	0.002	0.998	0.000
Q61.8 Other cystic kidney diseases	0.000	0.998	0.002
Q61.5 Medullary cystic kidney	0.000	0.998	0.002
Q61.1 Polycystic kidney, infantile type	0.000	0.998	0.002
Q64.4 Malformation of urachus	0.000	0.998	0.002
E50.9 Vitamin A deficiency, unspecified	0.002	0.998	0.000
E50.8 Other manifestations of vitamin A deficiency	0.002	0.998	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.002	0.998	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.002	0.998	0.000
E50.5 Vitamin A deficiency with night blindness	0.002	0.998	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.002	0.998	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.002	0.998	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.002	0.998	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.002	0.998	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.002	0.998	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.002	0.998	0.000
E64.8 Sequelae of other nutritional deficiencies	0.002	0.998	0.000
E64.3 Sequelae of rickets	0.002	0.998	0.000
E64.2 Sequelae of vitamin C deficiency	0.002	0.998	0.000
E64.1 Sequelae of vitamin A deficiency	0.002	0.998	0.000
E64.0 Sequelae of protein-energy malnutrition	0.002	0.998	0.000
O34.1 Maternal care for tumour of corpus uteri	0.000	0.998	0.002
G30-G32 Other degenerative diseases of the nervous system	0.000	0.998	0.002
E05.5 Thyroid crisis or storm	0.002	0.998	0.000
E05.4 Thyrotoxicosis factitia	0.002	0.998	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.002	0.998	0.000
Q60-Q64 Congenital malformations of the urinary system	0.000	0.998	0.002
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.002	0.998	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.002	0.998	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.002	0.998	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.002	0.998	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.002	0.998	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.002	0.998	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.002	0.998	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.002	0.998	0.000
H65.0 Acute serous otitis media	0.002	0.998	0.000
L30.8 Other specified dermatitis	0.000	0.998	0.002
M22.3 Other derangements of patella	0.000	0.998	0.002
Q64.9 Congenital malformation of urinary system, unspecified	0.000	0.998	0.002
Q64.8 Other specified congenital malformations of urinary system	0.000	0.998	0.002
Q64.6 Congenital diverticulum of bladder	0.000	0.998	0.002
Q64.5 Congenital absence of bladder and urethra	0.000	0.998	0.002
Q64.2 Congenital posterior urethral valves	0.000	0.998	0.002
Q64.1 Exstrophy of urinary bladder	0.000	0.998	0.002
Q64.0 Epispadias	0.000	0.998	0.002
E56.9 Vitamin deficiency, unspecified	0.002	0.998	0.000
E56.8 Deficiency of other vitamins	0.002	0.998	0.000
E56.0 Deficiency of vitamin E	0.002	0.998	0.000
Q61.9 Cystic kidney disease, unspecified	0.000	0.998	0.002
H65.4 Other chronic nonsuppurative otitis media	0.002	0.998	0.000
M54.4 Lumbago with sciatica	0.000	0.998	0.002
Q63.2 Ectopic kidney	0.000	0.998	0.002
K72 Hepatic failure, not elsewhere classified	0.002	0.998	0.000
A04.8 Other specified bacterial intestinal infections	0.002	0.998	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.002	0.998	0.000
E06.3 Autoimmune thyroiditis	0.002	0.998	0.000
H72.0 Central perforation of tympanic membrane	0.002	0.998	0.000
Q63.3 Hyperplastic and giant kidney	0.000	0.998	0.002
Q64.7 Other congenital malformations of bladder and urethra	0.000	0.998	0.002
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.000	0.998	0.002
K75.2 Nonspecific reactive hepatitis	0.002	0.998	0.000
K75.1 Phlebitis of portal vein	0.002	0.998	0.000
H69 Other disorders of Eustachian tube	0.002	0.998	0.000
J11.1 Influenza with other respiratory manifestations, virus not identified	0.000	0.998	0.002
E86 Volume depletion	0.002	0.998	0.000
E56.1 Deficiency of vitamin K	0.002	0.998	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.000	0.998	0.002
H74.4 Polyp of middle ear	0.002	0.998	0.000
L20 Atopic dermatitis	0.000	0.998	0.002
M24.56 Contracture of joint (Lower leg)	0.000	0.998	0.002
D86.8 Sarcoidosis of other and combined sites	0.000	0.998	0.002
C01 Malignant neoplasm of base of tongue	0.000	0.998	0.002
E61 Deficiency of other nutrient elements	0.002	0.998	0.000
L30 Other dermatitis	0.000	0.998	0.002
I37.1 Pulmonary valve insufficiency	0.002	0.998	0.000
Q61.4 Renal dysplasia	0.000	0.998	0.002
E55 Vitamin D deficiency	0.001	0.998	0.001
D86.1 Sarcoidosis of lymph nodes	0.000	0.998	0.002
G60.0 Hereditary motor and sensory neuropathy	0.000	0.998	0.002
K74.3 Primary biliary cirrhosis	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations