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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4486004
log Bayes Factor = 23.5502
Chromosome 6   position 26,167,710  (GRCh37) Explore rs4486004 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
C85.1 B-cell lymphoma, unspecified
0.000 0.357 0.643
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.441 0.559
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.500 0.500
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.509 0.491
C81 Hodgkin's disease
0.000 0.523 0.477
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.526 0.474
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.539 0.461
C81.9 Hodgkin's disease, unspecified
0.000 0.556 0.444
C88 Malignant immunoproliferative diseases
0.000 0.572 0.428
C81.1 Nodular sclerosis
0.000 0.593 0.407
C85.0 Lymphosarcoma
0.000 0.599 0.401
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.599 0.401
C82.2 Large cell, follicular
0.000 0.604 0.396
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.624 0.376
C88.0 Waldenstrom's macroglobulinaemia
0.000 0.629 0.371
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.638 0.362
C82.3 Follicular lymphoma grade IIIa
0.000 0.640 0.360
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.641 0.358
C94 Other leukaemias of specified cell type
0.000 0.641 0.358
C93 Monocytic leukaemia
0.000 0.641 0.358
C86 Other specified types of T/NK-cell lymphoma
0.000 0.641 0.358
C82.0 Small cleaved cell, follicular
0.000 0.647 0.353
C82.6 Cutaneous follicle centre lymphoma
0.000 0.648 0.352
C82.5 Diffuse follicle centre lymphoma
0.000 0.648 0.352
C81.0 Lymphocytic predominance
0.000 0.650 0.350
C81.7 Other Hodgkin's disease
0.000 0.657 0.342
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.657 0.342
C81.3 Lymphocytic depletion
0.000 0.657 0.342
C81.2 Mixed cellularity
0.000 0.657 0.342
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.665 0.335
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.669 0.331
C82.4 Follicular lymphoma grade IIIb
0.000 0.672 0.328
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.683 0.317
C88.9 Malignant immunoproliferative disease, unspecified
0.000 0.693 0.307
C88.7 Other malignant immunoproliferative diseases
0.000 0.693 0.307
C88.3 Immunoproliferative small intestinal disease
0.000 0.693 0.307
C88.2 Gamma heavy chain disease
0.000 0.693 0.307
C88.1 Alpha heavy chain disease
0.000 0.693 0.307
C95 Leukaemia of unspecified cell type
0.000 0.694 0.306
C92 Myeloid leukaemia
0.000 0.694 0.306
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.732 0.268
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.000 0.741 0.259
C91 Lymphoid leukaemia
0.000 0.743 0.257
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.000 0.743 0.257
C86.5 Angioimmunoblastic T-cell lymphoma
0.000 0.743 0.257
C86.4 Blastic NK-cell lymphoma
0.000 0.743 0.257
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.000 0.743 0.257
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.000 0.743 0.257
C86.1 Hepatosplenic T-cell lymphoma
0.000 0.743 0.257
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.000 0.743 0.257
C93.9 Monocytic leukaemia, unspecified
0.000 0.743 0.257
C93.7 Other monocytic leukaemia
0.000 0.743 0.257
C93.3 Juvenile myelomonocytic leukaemia
0.000 0.743 0.257
C93.2 Subacute monocytic leukaemia
0.000 0.743 0.257
C93.1 Chronic monocytic leukaemia
0.000 0.743 0.257
C93.0 Acute monocytic leukaemia
0.000 0.743 0.257
C94.7 Other specified leukaemias
0.000 0.743 0.257
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.000 0.743 0.257
C94.5 Acute myelofibrosis
0.000 0.743 0.257
C94.4 Acute panmyelosis
0.000 0.743 0.257
C94.3 Mast cell leukaemia
0.000 0.743 0.257
C94.2 Acute megakaryoblastic leukaemia
0.000 0.743 0.257
C94.1 Chronic erythraemia
0.000 0.743 0.257
C94.0 Acute erythraemia and erythroleukaemia
0.000 0.743 0.257
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.743 0.257
C96.8 Histiocytic sarcoma
0.000 0.743 0.257
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.743 0.257
C96.6 Unifocal Langerhans-cell histiocytosis
0.000 0.743 0.257
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.000 0.743 0.257
C96.4 Sarcoma of dendritic cells (accessory cells)
0.000 0.743 0.257
C96.3 True histiocytic lymphoma
0.000 0.743 0.257
C96.2 Malignant mast cell tumour
0.000 0.743 0.257
C96.1 Malignant histiocytosis
0.000 0.743 0.257
C96.0 Letterer-Siwe disease
0.000 0.743 0.257
C90 Multiple myeloma and malignant plasma cell neoplasms
0.000 0.753 0.246
C92.1 Chronic myeloid leukaemia
0.000 0.761 0.239
C83.7 Burkitt's tumour
0.000 0.762 0.238
C83.6 Undifferentiated (diffuse)
0.000 0.762 0.238
C83.5 Lymphoblastic (diffuse)
0.000 0.762 0.238
C83.4 Immunoblastic (diffuse)
0.000 0.762 0.238
C83.2 Mixed small and large cell (diffuse)
0.000 0.762 0.238
C83.0 Small cell (diffuse)
0.000 0.764 0.236
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.777 0.222
C95.7 Other leukaemia of unspecified cell type
0.000 0.780 0.219
C95.2 Subacute leukaemia of unspecified cell type
0.000 0.780 0.219
C95.1 Chronic leukaemia of unspecified cell type
0.000 0.780 0.219
C95.0 Acute leukaemia of unspecified cell type
0.000 0.780 0.219
C92.9 Myeloid leukaemia, unspecified
0.000 0.781 0.219
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.000 0.781 0.219
C92.7 Other myeloid leukaemia
0.000 0.781 0.219
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.000 0.781 0.219
C92.5 Acute myelomonocytic leukaemia
0.000 0.781 0.219
C92.3 Myeloid sarcoma
0.000 0.781 0.219
C92.2 Subacute myeloid leukaemia
0.000 0.781 0.219
K90.0 Coeliac disease
0.000 0.784 0.216
C91.9 Lymphoid leukaemia, unspecified
0.000 0.795 0.205
C90.2 Plasmacytoma, extramedullary
0.000 0.803 0.197
C83.1 Small cleaved cell (diffuse)
0.000 0.805 0.195
C91.5 Adult T-cell leukaemia
0.000 0.811 0.188
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.815 0.185
C91.7 Other lymphoid leukaemia
0.000 0.815 0.185
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.815 0.185
C91.3 Prolymphocytic leukaemia
0.000 0.815 0.185
C91.2 Subacute lymphocytic leukaemia
0.000 0.815 0.185
C92.0 Acute myeloid leukaemia
0.000 0.817 0.183
C92.4 Acute promyelocytic leukaemia
0.000 0.820 0.180
C90.1 Plasma cell leukaemia
0.000 0.823 0.177
C91.0 Acute lymphoblastic leukaemia
0.000 0.824 0.176
C83.3 Large cell (diffuse)
0.000 0.825 0.175
C95.9 Leukaemia, unspecified
0.000 0.833 0.167
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.840 0.160
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.840 0.160
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.840 0.160
C84.3 Lymphoepithelioid lymphoma
0.000 0.840 0.160
C84.2 T-zone lymphoma
0.000 0.840 0.160
C84.1 Sezary's diease
0.000 0.840 0.160
C90.3 Solitary plasmacytoma
0.000 0.845 0.154
C91.4 Hairy-cell leukaemia
0.000 0.855 0.145
C84.0 Mycosis fungoides
0.000 0.857 0.142
C84.5 Other and unspecified T-cell lymphomas
0.000 0.858 0.142
C84.8 Cutaneous T-cell lymphoma, unspecified
0.001 0.862 0.138
C84.4 Peripheral T-cell lymphoma
0.000 0.868 0.132
K90 Intestinal malabsorption
0.000 0.870 0.130
E83 Disorders of mineral metabolism
0.000 0.876 0.124
K90.9 Intestinal malabsorption, unspecified
0.000 0.881 0.119
C91.1 Chronic lymphocytic leukaemia
0.000 0.890 0.110
K90.3 Pancreatic steatorrhoea
0.000 0.907 0.093
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.907 0.093
K90.1 Tropical sprue
0.000 0.907 0.093
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.911 0.089
E83.8 Other disorders of mineral metabolism
0.000 0.911 0.089
E83.2 Disorders of zinc metabolism
0.000 0.911 0.089
E83.0 Disorders of copper metabolism
0.000 0.911 0.089
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.911 0.088
E83.4 Disorders of magnesium metabolism
0.000 0.913 0.087
K90.8 Other intestinal malabsorption
0.000 0.929 0.070
E83.3 Disorders of phosphorus metabolism
0.000 0.945 0.055
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.000 0.946 0.054
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.000 0.947 0.053
C90.0 Multiple myeloma
0.000 0.947 0.052
T84.1 Mechanical complication of internal fixation device of bones of limb
0.000 0.948 0.052
T81 Complications of procedures, not elsewhere classified
0.000 0.950 0.050
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.000 0.951 0.049
T81.3 Disruption of operation wound, not elsewhere classified
0.000 0.951 0.049
T84.0 Mechanical complication of internal joint prosthesis
0.000 0.952 0.048
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.000 0.952 0.047
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.000 0.953 0.047
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.000 0.954 0.046
T88 Other complications of surgical and medical care, not elsewhere classified
0.000 0.956 0.044
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.000 0.958 0.042
T86 Failure and rejection of transplanted organs and tissues
0.000 0.958 0.042
T81.8 Other complications of procedures, not elsewhere classified
0.000 0.961 0.039
T86.0 Bone-marrow transplant rejection
0.000 0.961 0.039
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.000 0.961 0.038
T88.5 Other complications of anaesthesia
0.000 0.962 0.038
T85 Complications of other internal prosthetic devices, implants and grafts
0.000 0.962 0.038
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.000 0.962 0.038
T84.3 Mechanical complication of other bone devices, implants and grafts
0.000 0.964 0.036
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.000 0.964 0.036
T81.7 Vascular complications following a procedure, not elsewhere classified
0.000 0.965 0.035
T87 Complications peculiar to reattachment and amputation
0.000 0.966 0.034
T84.2 Mechanical complication of internal fixation device of other bones
0.000 0.966 0.034
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.000 0.966 0.034
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.000 0.967 0.033
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.000 0.967 0.033
M17.9 Gonarthrosis, unspecified
0.000 0.967 0.033
T86.4 Liver transplant failure and rejection
0.000 0.967 0.032
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.000 0.967 0.033
T86.8 Failure and rejection of other transplanted organs and tissues
0.000 0.967 0.032
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.000 0.968 0.032
T88.9 Complication of surgical and medical care, unspecified
0.000 0.968 0.031
T88.3 Malignant hyperthermia due to anaesthesis
0.000 0.968 0.031
T88.2 Shock due to anaesthesia
0.000 0.968 0.031
T88.1 Other complications following immunisation, not elsewhere classified
0.000 0.968 0.031
T88.0 Infection following immunisation
0.000 0.968 0.031
T82.1 Mechanical complication of cardiac electronic device
0.000 0.969 0.031
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.000 0.969 0.031
T86.9 Failure and rejection of unspecified transplanted organ and tissue
0.000 0.970 0.030
T86.3 Heart-lung transplant failure and rejection
0.000 0.970 0.030
T86.2 Heart transplant failure and rejection
0.000 0.970 0.030
T88.7 Unspecified adverse effect of drug or medicament
0.000 0.970 0.030
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.000 0.970 0.030
E83.5 Disorders of calcium metabolism
0.000 0.970 0.030
T87.6 Other and unspecified complications of amputation stump
0.000 0.971 0.029
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.000 0.971 0.029
T85.4 Mechanical complication of breast prosthesis and implant
0.000 0.972 0.028
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.000 0.972 0.028
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.000 0.974 0.026
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.000 0.974 0.026
T83.3 Mechanical complication of intra-uterine contraceptive device
0.000 0.974 0.026
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.000 0.975 0.025
T87.2 Complications of other reattached body part
0.000 0.975 0.025
T87.1 Complications of reattached (part of) lower extremity
0.000 0.975 0.025
T87.0 Complications of reattached (part of) upper extremity
0.000 0.975 0.025
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.000 0.976 0.024
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.000 0.976 0.023
T88.4 Failed or difficult intubation
0.000 0.977 0.023
T83.1 Mechanical complication of other urinary devices and implants
0.000 0.977 0.023
T87.3 Neuroma of amputation stump
0.000 0.977 0.023
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.000 0.977 0.023
T87.5 Necrosis of amputation stump
0.000 0.977 0.022
T83.2 Mechanical complication of graft of urinary organ
0.000 0.978 0.022
T81.9 Unspecified complication of procedure
0.000 0.979 0.021
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.000 0.979 0.021
T82.4 Mechanical complication of vascular dialysis catheter
0.000 0.979 0.021
T87.4 Infection of amputation stump
0.000 0.979 0.020
I10 Essential (primary) hypertension
0.000 0.980 0.020
T85.2 Mechanical complication of intraocular lens
0.000 0.980 0.020
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.000 0.980 0.020
K90-K93 Other diseases of the digestive system
0.000 0.980 0.020
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.000 0.980 0.019
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.000 0.981 0.019
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.000 0.981 0.019
T83.0 Mechanical complication of urinary (indwelling) catheter
0.000 0.982 0.018
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.000 0.983 0.017
T82.0 Mechanical complication of heart valve prosthesis
0.000 0.983 0.017
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.000 0.983 0.017
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.000 0.983 0.017
T82.3 Mechanical complication of other vascular grafts
0.000 0.983 0.016
T86.1 Kidney transplant failure and rejection
0.000 0.984 0.016
T80 Complications following infusion, transfusion and therapeutic injection
0.001 0.984 0.015
E10.1 With ketoacidosis
0.000 0.985 0.015
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.000 0.985 0.015
E10 Insulin-dependent diabetes mellitus
0.000 0.985 0.015
D75.1 Secondary polycythaemia
0.000 0.985 0.015
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.000 0.985 0.014
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.986 0.014
E11.4 With neurological complications
0.000 0.986 0.014
E10.0 With coma
0.000 0.986 0.014
N43.3 Hydrocele, unspecified
0.013 0.987 0.000
E10.5 With peripheral circulatory complications
0.000 0.987 0.013
E80.4 Gilbert's syndrome
0.000 0.987 0.013
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.987 0.012
N28.9 Disorder of kidney and ureter, unspecified
0.000 0.988 0.012
E10.2 With renal complications
0.000 0.988 0.012
E11 Non-insulin-dependent diabetes mellitus
0.000 0.988 0.012
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.000 0.988 0.012
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.988 0.012
T81.4 Infection following a procedure, not elsewhere classified
0.000 0.988 0.012
N28.8 Other specified disorders of kidney and ureter
0.000 0.988 0.012
E11.2 With renal complications
0.000 0.988 0.011
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection
0.001 0.988 0.011
T80.6 Other serum reactions
0.001 0.988 0.011
T80.5 Anaphylactic shock due to serum
0.001 0.988 0.011
T80.4 Rh incompatibility reaction
0.001 0.988 0.011
T80.3 ABO incompatibility reaction
0.001 0.988 0.011
T80.0 Air embolism following infusion, transfusion and therapeutic injection
0.001 0.988 0.011
E10.4 With neurological complications
0.000 0.988 0.011
E10-E14 Diabetes mellitus
0.000 0.988 0.012
E10.8 With unspecified complications
0.000 0.989 0.011
E70-E90 Metabolic disorders
0.000 0.989 0.011
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.989 0.011
N28 Other disorders of kidney and ureter, not elsewhere classified
0.000 0.989 0.011
E10.7 With multiple complications
0.000 0.989 0.011
T80.1 Vascular complications following infusion, transfusion and therapeutic injection
0.001 0.989 0.010
D86.9 Sarcoidosis, unspecified
0.000 0.989 0.011
K91.4 Colostomy and enterostomy malfunction
0.000 0.989 0.011
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.989 0.010
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.989 0.010
K93.1 Megacolon in Chagas' disease
0.000 0.989 0.010
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.989 0.010
E11.5 With peripheral circulatory complications
0.000 0.990 0.010
F32 Depressive episode
0.010 0.990 0.000
F33 Recurrent depressive disorder
0.010 0.990 0.000
F30-F39 Mood [affective] disorders
0.010 0.990 0.000
D86 Sarcoidosis
0.000 0.990 0.010
E80.6 Other disorders of bilirubin metabolism
0.000 0.990 0.010
F32.3 Severe depressive episode with psychotic symptoms
0.010 0.990 0.000
E10.6 With other specified complications
0.000 0.990 0.010
F32.2 Severe depressive episode without psychotic symptoms
0.010 0.990 0.000
E11.0 With coma
0.000 0.991 0.009
F39 Unspecified mood [affective] disorder
0.009 0.991 0.000
F32.0 Mild depressive episode
0.009 0.991 0.000
G43.9 Migraine, unspecified
0.000 0.991 0.009
D86.0 Sarcoidosis of lung
0.000 0.991 0.009
E73 Lactose intolerance
0.000 0.991 0.009
E11.6 With other specified complications
0.000 0.991 0.009
E11.1 With ketoacidosis
0.000 0.991 0.009
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.009 0.991 0.000
E11.7 With multiple complications
0.000 0.991 0.009
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.991 0.009
E80.5 Crigler-Najjar syndrome
0.000 0.991 0.009
E80.3 Defects of catalase and peroxydase
0.000 0.991 0.009
E80.2 Other porphyria
0.000 0.991 0.009
E80.1 Porphyria cutanea tarda
0.000 0.991 0.009
E80.0 Hereditary erythropoietic porphyria
0.000 0.991 0.009
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.009 0.991 0.000
D86.1 Sarcoidosis of lymph nodes
0.000 0.991 0.009
F31 Bipolar affective disorder
0.009 0.991 0.000
F33.9 Recurrent depressive disorder, unspecified
0.009 0.991 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.991 0.009
E74 Other disorders of carbohydrate metabolism
0.000 0.991 0.009
N28.0 Ischaemia and infarction of kidney
0.000 0.991 0.009
D86.8 Sarcoidosis of other and combined sites
0.000 0.991 0.009
E10.3 With ophthalmic complications
0.000 0.991 0.009
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.008 0.991 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.991 0.008
F33.0 Recurrent depressive disorder, current episode mild
0.008 0.992 0.000
K91.1 Postgastric surgery syndromes
0.000 0.992 0.008
E84 Cystic fibrosis
0.000 0.992 0.008
E77 Disorders of glycoprotein metabolism
0.000 0.992 0.008
E76 Disorders of glycosaminoglycan metabolism
0.000 0.992 0.008
E72 Other disorders of amino-acid metabolism
0.000 0.992 0.008
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.992 0.008
E70 Disorders of aromatic amino-acid metabolism
0.000 0.992 0.008
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.992 0.008
F32.1 Moderate depressive episode
0.008 0.992 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.992 0.008
K91.3 Postoperative intestinal obstruction
0.000 0.992 0.008
F33.4 Recurrent depressive disorder, currently in remission
0.008 0.992 0.000
L53.9 Erythematous condition, unspecified
0.000 0.992 0.008
E79 Disorders of purine and pyrimidine metabolism
0.000 0.992 0.008
F32.8 Other depressive episodes
0.008 0.992 0.000
N26 Unspecified contracted kidney
0.000 0.992 0.008
E27 Other disorders of adrenal gland
0.000 0.992 0.008
F34 Persistent mood [affective] disorders
0.008 0.992 0.000
F33.8 Other recurrent depressive disorders
0.008 0.992 0.000
E27.2 Addisonian crisis
0.000 0.992 0.008
E88 Other metabolic disorders
0.000 0.992 0.007
E73.9 Lactose intolerance, unspecified
0.000 0.992 0.007
F38 Other mood [affective] disorders
0.007 0.992 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.993 0.007
N25-N29 Other disorders of kidney and ureter
0.000 0.993 0.007
K91.5 Postcholecystectomy syndrome
0.000 0.993 0.007
G25.8 Other specified extrapyramidal and movement disorders
0.000 0.993 0.007
E13 Other specified diabetes mellitus
0.000 0.993 0.007
D86.3 Sarcoidosis of skin
0.000 0.993 0.007
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.993 0.007
F33.1 Recurrent depressive disorder, current episode moderate
0.007 0.993 0.000
R40.0 Somnolence
0.007 0.993 0.000
H93.1 Tinnitus
0.007 0.993 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.007 0.993 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.007 0.993 0.000
S42.20 Fracture of upper end of humerus (closed)
0.000 0.993 0.007
F31.9 Bipolar affective disorder, unspecified
0.007 0.993 0.000
E11.8 With unspecified complications
0.000 0.993 0.007
E73.8 Other lactose intolerance
0.000 0.993 0.007
E73.1 Secondary lactase deficiency
0.000 0.993 0.007
E73.0 Congenital lactase deficiency
0.000 0.993 0.007
F31.7 Bipolar affective disorder, currently in remission
0.007 0.993 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.993 0.007
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.993 0.007
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.001 0.993 0.006
E11.3 With ophthalmic complications
0.000 0.993 0.007
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.993 0.006
F31.8 Other bipolar affective disorders
0.006 0.993 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.993 0.006
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.993 0.006
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.993 0.006
E74.2 Disorders of galactose metabolism
0.000 0.993 0.006
E74.1 Disorders of fructose metabolism
0.000 0.993 0.006
E74.0 Glycogen storage disease
0.000 0.993 0.006
T80.2 Infections following infusion, transfusion and therapeutic injection
0.001 0.993 0.006
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.993 0.006
F31.0 Bipolar affective disorder, current episode hypomanic
0.006 0.994 0.000
G43 Migraine
0.000 0.994 0.006
E12.9 Without complications
0.000 0.994 0.006
E12.8 With unspecified complications
0.000 0.994 0.006
E12.7 With multiple complications
0.000 0.994 0.006
E12.6 With other specified complications
0.000 0.994 0.006
E12.5 With peripheral circulatory complications
0.000 0.994 0.006
E12.4 With neurological complications
0.000 0.994 0.006
E12.3 With ophthalmic complications
0.000 0.994 0.006
E12.2 With renal complications
0.000 0.994 0.006
E12.1 With ketoacidosis
0.000 0.994 0.006
E12.0 With coma
0.000 0.994 0.006
E10.9 Without complications
0.000 0.994 0.006
F30 Manic episode
0.006 0.994 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.994 0.006
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.994 0.006
E70.3 Albinism
0.000 0.994 0.006
E70.2 Disorders of tyrosine metabolism
0.000 0.994 0.006
E70.1 Other hyperphenylalaninaemias
0.000 0.994 0.006
E70.0 Classical phenylketonuria
0.000 0.994 0.006
E71.3 Disorders of fatty-acid metabolism
0.000 0.994 0.006
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.994 0.006
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.994 0.006
E71.0 Maple-syrup-urine disease
0.000 0.994 0.006
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.994 0.006
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.994 0.006
E72.5 Disorders of glycine metabolism
0.000 0.994 0.006
E72.4 Disorders of ornithine metabolism
0.000 0.994 0.006
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.994 0.006
E72.2 Disorders of urea cycle metabolism
0.000 0.994 0.006
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.994 0.006
E72.0 Disorders of amino-acid transport
0.000 0.994 0.006
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.994 0.006
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.994 0.006
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.994 0.006
E76.2 Other mucopolysaccharidoses
0.000 0.994 0.006
E76.1 Mucopolysaccharidosis, type II
0.000 0.994 0.006
E76.0 Mucopolysaccharidosis, type I
0.000 0.994 0.006
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.994 0.006
E77.8 Other disorders of glycoprotein metabolism
0.000 0.994 0.006
E77.1 Defects in glycoprotein degradation
0.000 0.994 0.006
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.994 0.006
E84.9 Cystic fibrosis, unspecified
0.000 0.994 0.006
E84.8 Cystic fibrosis with other manifestations
0.000 0.994 0.006
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.994 0.006
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.994 0.006
G51.0 Bell's palsy
0.000 0.994 0.006
J38.3 Other diseases of vocal cords
0.000 0.994 0.006
E75.6 Lipid storage disorder, unspecified
0.000 0.994 0.006
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.994 0.006
E75.3 Sphingolipidosis, unspecified
0.000 0.994 0.006
E75.2 Other sphingolipidosis
0.000 0.994 0.006
E75.1 Other gangliosidosis
0.000 0.994 0.006
E75.0 GM2 gangliosidosis
0.000 0.994 0.006
E16 Other disorders of pancreatic internal secretion
0.000 0.994 0.006
F34.1 Dysthymia
0.006 0.994 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.994 0.006
E27.9 Disorder of adrenal gland, unspecified
0.000 0.994 0.006
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.994 0.006
E75.5 Other lipid storage disorders
0.000 0.994 0.006
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.994 0.006
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.994 0.006
E79.1 Lesch-Nyhan syndrome
0.000 0.994 0.006
E27.5 Adrenomedullary hyperfunction
0.000 0.994 0.006
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.994 0.006
E27.0 Other adrenocortical overactivity
0.000 0.994 0.006
F34.9 Persistent mood [affective] disorder, unspecified
0.006 0.994 0.000
F34.8 Other persistent mood [affective] disorders
0.006 0.994 0.000
F34.0 Cyclothymia
0.006 0.994 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.006 0.994 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.994 0.006
E88.8 Other specified metabolic disorders
0.000 0.994 0.006
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.994 0.006
F38.8 Other specified mood [affective] disorders
0.005 0.994 0.000
F38.1 Other recurrent mood [affective] disorders
0.005 0.994 0.000
F38.0 Other single mood [affective] disorders
0.005 0.994 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.006 0.994 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.000 0.994 0.006
E88.3 Tumour lysis syndrome
0.000 0.994 0.005
G43.1 Migraine with aura [classical migraine]
0.000 0.994 0.006
E16.2 Hypoglycaemia, unspecified
0.000 0.994 0.006
G43.8 Other migraine
0.000 0.994 0.005
E13.8 With unspecified complications
0.000 0.994 0.005
E13.7 With multiple complications
0.000 0.994 0.005
E13.6 With other specified complications
0.000 0.994 0.005
E13.5 With peripheral circulatory complications
0.000 0.994 0.005
E13.4 With neurological complications
0.000 0.994 0.005
E13.3 With ophthalmic complications
0.000 0.994 0.005
E13.2 With renal complications
0.000 0.994 0.005
E13.1 With ketoacidosis
0.000 0.994 0.005
E13.0 With coma
0.000 0.994 0.005
M17 Gonarthrosis [arthrosis of knee]
0.000 0.995 0.005
E27.8 Other specified disorders of adrenal gland
0.000 0.995 0.005
M25.46 Effusion of joint (Lower leg)
0.000 0.995 0.005
G25 Other extrapyramidal and movement disorders
0.000 0.995 0.005
N25 Disorders resulting from impaired renal tubular function
0.000 0.995 0.005
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.995 0.005
F30.2 Mania with psychotic symptoms
0.005 0.995 0.000
D80-D89 Certain disorders involving the immune mechanism
0.000 0.995 0.005
E40-E46 Malnutrition
0.000 0.995 0.005
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.995 0.005
N27 Small kidney of unknown cause
0.000 0.995 0.005
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.995 0.005
E89.3 Postprocedural hypopituitarism
0.000 0.995 0.005
E20-E35 Disorders of other endocrine glands
0.000 0.995 0.005
E15 Nondiabetic hypoglycaemic coma
0.000 0.995 0.005
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.005 0.995 0.000
G43.3 Complicated migraine
0.000 0.995 0.005
G43.2 Status migrainosus
0.000 0.995 0.005
M84.1 Nonunion of fracture [pseudarthrosis]
0.005 0.995 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.005 0.995 0.000
F30.1 Mania without psychotic symptoms
0.005 0.995 0.000
E85 Amyloidosis
0.000 0.995 0.004
G25.0 Essential tremor
0.000 0.995 0.005
E88.9 Metabolic disorder, unspecified
0.000 0.995 0.004
F30.8 Other manic episodes
0.005 0.995 0.000
G25.3 Myoclonus
0.000 0.995 0.005
G43.0 Migraine without aura [common migraine]
0.000 0.995 0.005
Z22.3 Carrier of other specified bacterial diseases
0.000 0.995 0.005
J38.4 Oedema of larynx
0.000 0.995 0.005
J18.0 Bronchopneumonia, unspecified
0.000 0.995 0.005
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.995 0.004
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.995 0.004
E16.4 Abnormal secretion of gastrin
0.000 0.995 0.004
E16.3 Increased secretion of glucagon
0.000 0.995 0.004
M17.3 Other posttraumatic gonarthrosis
0.000 0.995 0.004
D84.9 Immunodeficiency, unspecified
0.000 0.996 0.004
D84 Other immunodeficiencies
0.000 0.996 0.004
E16.1 Other hypoglycaemia
0.000 0.996 0.004
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.996 0.004
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.996 0.004
E89.5 Postprocedural testicular hypofunction
0.000 0.996 0.004
E89.4 Postprocedural ovarian failure
0.000 0.996 0.004
E89.1 Postprocedural hypoinsulinaemia
0.000 0.996 0.004
L53 Other erythematous conditions
0.000 0.996 0.004
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.004 0.996 0.000
J38.2 Nodules of vocal cords
0.000 0.996 0.004
H93 Other disorders of ear, not elsewhere classified
0.004 0.996 0.000
N29.8 Other disorders of kidney and ureter in other diseases classified elsewhere
0.000 0.996 0.004
N29.1 Other disorders of kidney and ureter in infectious and parasitic diseases classified elsewhere
0.000 0.996 0.004
N29.0 Late syphilis of kidney
0.000 0.996 0.004
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.004 0.996 0.000
H66.9 Otitis media, unspecified
0.000 0.996 0.004
M17.4 Other secondary gonarthrosis, bilateral
0.000 0.996 0.004
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.004 0.996 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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