TreeWAS – Variant ID: rs4523957

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.055	0.945
M23.2 Derangement of meniscus due to old tear or injury	0.000	0.082	0.918
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.086	0.914
M23 Internal derangement of knee	0.000	0.113	0.887
M23.3 Other meniscus derangements	0.000	0.124	0.876
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.201	0.799
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.000	0.207	0.793
M23.6 Other spontaneous disruption of ligament(s) of knee	0.000	0.208	0.791
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.265	0.735
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.277	0.723
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.278	0.722
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.287	0.713
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.000	0.303	0.697
M23.30 Other meniscus derangements (Multiple sites)	0.000	0.314	0.686
M23.9 Internal derangement of knee, unspecified	0.000	0.318	0.682
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.000	0.341	0.658
M23.4 Loose body in knee	0.000	0.346	0.654
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.000	0.354	0.646
M23.0 Cystic meniscus	0.000	0.357	0.643
M23.37 Other meniscus derangements-Capsular lig	0.000	0.372	0.628
M23.8 Other internal derangements of knee	0.000	0.389	0.611
M23.1 Discoid meniscus (congenital)	0.000	0.392	0.608
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.000	0.413	0.587
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.432	0.567
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.000	0.432	0.567
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.000	0.432	0.567
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.000	0.432	0.567
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.432	0.567
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.432	0.567
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.432	0.567
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.000	0.432	0.567
M23.43 Loose body in knee-Med lig/oth men	0.000	0.434	0.566
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.000	0.473	0.527
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.000	0.474	0.526
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.474	0.526
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.484	0.516
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.000	0.501	0.499
M23.40 Loose body in knee-Mult sites	0.000	0.501	0.498
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.507	0.492
M23.5 Chronic instability of knee	0.000	0.508	0.492
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.509	0.491
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.000	0.511	0.489
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.000	0.511	0.489
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.000	0.511	0.489
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.511	0.489
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.511	0.489
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.000	0.511	0.489
M23.47 Loose body in knee-Capsular lig	0.000	0.531	0.469
M23.45 Loose body in knee-Pst hrn lat men	0.000	0.531	0.469
M23.42 Loose body in knee-Pst lig/hrn men	0.000	0.531	0.469
M23.87 Other internal derangements of knee (Capsular ligament)	0.000	0.538	0.462
M23.07 Cystic meniscus-Capsular lig	0.000	0.539	0.461
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.000	0.539	0.461
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.539	0.461
M23.00 Cystic meniscus (Multiple sites)	0.000	0.539	0.461
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.544	0.456
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.552	0.448
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.000	0.561	0.439
M23.46 Loose body in knee-O/unsp lat men	0.000	0.561	0.439
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.000	0.562	0.438
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.000	0.564	0.436
M23.17 Discoid meniscus (congenital)-Capsular lig	0.000	0.564	0.436
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.000	0.564	0.436
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.564	0.436
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.564	0.436
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.564	0.436
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.564	0.436
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.000	0.564	0.436
M23.44 Loose body in knee-Lat lig/ant men	0.000	0.566	0.433
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.000	0.567	0.433
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.567	0.432
M23.41 Loose body in knee-Ant lig/hrn men	0.000	0.568	0.432
I25.1 Atherosclerotic heart disease	0.000	0.579	0.421
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.592	0.408
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.000	0.592	0.408
M23.49 Loose body in knee-Unspec lig/men	0.000	0.594	0.406
I25 Chronic ischaemic heart disease	0.000	0.602	0.398
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.621	0.379
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.622	0.378
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.000	0.625	0.375
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.628	0.371
M23.50 Chronic instability of knee (Multiple sites)	0.000	0.638	0.362
I25.5 Ischaemic cardiomyopathy	0.000	0.638	0.362
I25.2 Old myocardial infarction	0.000	0.642	0.358
M23.57 Chronic instability of knee (Capsular ligament)	0.000	0.647	0.353
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.000	0.647	0.353
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.647	0.353
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.647	0.353
I25.4 Coronary artery aneurysm	0.000	0.648	0.352
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.654	0.346
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.000	0.670	0.330
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.681	0.318
I25.3 Aneurysm of heart	0.000	0.715	0.285
M23.80 Other internal derangements of knee (Multiple sites)	0.000	0.717	0.283
I25.6 Silent myocardial ischaemia	0.000	0.746	0.254
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.756	0.244
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.000	0.760	0.240
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.766	0.234
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.766	0.233
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.783	0.217
I20-I25 Ischaemic heart diseases	0.000	0.895	0.105
I24 Other acute ischaemic heart diseases	0.000	0.909	0.091
I22 Subsequent myocardial infarction	0.000	0.909	0.091
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.915	0.085
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.920	0.080
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.921	0.079
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.925	0.075
I23 Certain current complications following acute myocardial infarction	0.000	0.928	0.072
I22.8 Subsequent myocardial infarction of other sites	0.000	0.934	0.066
M17.9 Gonarthrosis, unspecified	0.000	0.936	0.064
I24.1 Dressler's syndrome	0.000	0.940	0.060
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.944	0.056
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.948	0.052
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.948	0.052
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.948	0.052
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.948	0.052
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.948	0.052
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.948	0.052
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.949	0.051
I23.8 Other current complications following acute myocardial infarction	0.000	0.950	0.050
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.000	0.953	0.047
I34.0 Mitral (valve) insufficiency	0.041	0.959	0.000
C71 Malignant neoplasm of brain	0.037	0.963	0.000
C71.8 Overlapping lesion of brain	0.034	0.966	0.000
C71.2 Temporal lobe	0.034	0.966	0.000
C71.9 Brain, unspecified	0.034	0.966	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.967	0.033
C71.0 Cerebrum, except lobes and ventricles	0.032	0.967	0.000
C71.1 Frontal lobe	0.032	0.968	0.000
C71.3 Parietal lobe	0.032	0.968	0.000
I21.9 Acute myocardial infarction, unspecified	0.000	0.969	0.031
I21 Acute myocardial infarction	0.000	0.969	0.031
C71.6 Cerebellum	0.027	0.973	0.000
C71.5 Cerebral ventricle	0.027	0.973	0.000
I34 Nonrheumatic mitral valve disorders	0.026	0.974	0.000
K41 Femoral hernia	0.000	0.974	0.026
C71.4 Occipital lobe	0.025	0.975	0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.000	0.975	0.025
C71.7 Brain stem	0.024	0.976	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.023	0.977	0.000
I24.8 Other forms of acute ischaemic heart disease	0.000	0.977	0.023
K73.9 Chronic hepatitis, unspecified	0.000	0.978	0.022
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.978	0.022
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.978	0.022
I34.2 Nonrheumatic mitral (valve) stenosis	0.020	0.980	0.000
I34.1 Mitral (valve) prolapse	0.020	0.980	0.000
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.000	0.980	0.019
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.981	0.019
K41.1 Bilateral femoral hernia, with gangrene	0.000	0.981	0.018
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.000	0.981	0.018
K73 Chronic hepatitis, not elsewhere classified	0.000	0.982	0.018
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.000	0.982	0.018
I34.8 Other nonrheumatic mitral valve disorders	0.017	0.983	0.000
D52.9 Folate deficiency anaemia, unspecified	0.017	0.983	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.016	0.984	0.000
K72 Hepatic failure, not elsewhere classified	0.000	0.984	0.016
K70-K77 Diseases of liver	0.000	0.984	0.016
I21.4 Acute subendocardial myocardial infarction	0.000	0.985	0.015
K75.4 Autoimmune hepatitis	0.000	0.985	0.015
K74.3 Primary biliary cirrhosis	0.000	0.985	0.015
K72.0 Acute and subacute hepatic failure	0.000	0.985	0.015
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.985	0.015
K75 Other inflammatory liver diseases	0.000	0.985	0.015
K72.9 Hepatic failure, unspecified	0.000	0.985	0.015
C69 Malignant neoplasm of eye and adnexa	0.014	0.985	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.986	0.014
M65.9 Synovitis and tenosynovitis, unspecified	0.000	0.987	0.013
K74 Fibrosis and cirrhosis of liver	0.000	0.987	0.013
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.987	0.013
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.987	0.013
I20 Angina pectoris	0.000	0.987	0.013
D86.8 Sarcoidosis of other and combined sites	0.000	0.988	0.012
C69.3 Choroid	0.012	0.988	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.000	0.988	0.012
K75.9 Inflammatory liver disease, unspecified	0.000	0.988	0.012
C69.6 Orbit	0.012	0.988	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.988	0.012
K71 Toxic liver disease	0.000	0.988	0.012
C69.0 Conjunctiva	0.011	0.989	0.000
K77 Liver disorders in diseases classified elsewhere	0.000	0.989	0.011
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.989	0.011
D86 Sarcoidosis	0.000	0.989	0.011
C69.4 Ciliary body	0.011	0.989	0.000
K75.2 Nonspecific reactive hepatitis	0.000	0.989	0.011
K75.1 Phlebitis of portal vein	0.000	0.989	0.011
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.000	0.989	0.011
C69.2 Retina	0.011	0.989	0.000
C69.8 Overlapping lesion of eye and adnexa	0.011	0.989	0.000
C69.5 Lachrymal gland and duct	0.011	0.989	0.000
C69.1 Cornea	0.011	0.989	0.000
C70 Malignant neoplasm of meninges	0.010	0.990	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.010	0.990	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.990	0.010
K74.5 Biliary cirrhosis, unspecified	0.000	0.990	0.010
K72.1 Chronic hepatic failure	0.000	0.990	0.010
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.000	0.990	0.010
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.000	0.990	0.010
K74.4 Secondary biliary cirrhosis	0.000	0.990	0.010
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.990	0.010
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.000	0.990	0.010
C69.9 Eye, unspecified	0.009	0.991	0.000
K74.1 Hepatic sclerosis	0.000	0.991	0.009
I05.9 Mitral valve disease, unspecified	0.009	0.991	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.000	0.991	0.009
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.991	0.009
K75.8 Other specified inflammatory liver diseases	0.000	0.991	0.009
K70 Alcoholic liver disease	0.000	0.991	0.009
K71.9 Toxic liver disease, unspecified	0.000	0.991	0.009
Z92.3 Personal history of irradiation	0.009	0.991	0.000
M17 Gonarthrosis [arthrosis of knee]	0.000	0.991	0.009
K71.8 Toxic liver disease with other disorders of liver	0.000	0.991	0.008
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.991	0.008
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.991	0.008
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.991	0.008
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.991	0.008
K71.2 Toxic liver disease with acute hepatitis	0.000	0.991	0.008
K71.0 Toxic liver disease with cholestasis	0.000	0.991	0.008
D86.0 Sarcoidosis of lung	0.000	0.991	0.009
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.991	0.008
I05 Rheumatic mitral valve diseases	0.008	0.992	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.992	0.008
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.992	0.008
M43.16 Spondylolisthesis (Lumbar region)	0.000	0.992	0.008
I05.1 Rheumatic mitral insufficiency	0.008	0.992	0.000
D86.3 Sarcoidosis of skin	0.000	0.992	0.008
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.000	0.992	0.008
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.992	0.008
K70.3 Alcoholic cirrhosis of liver	0.000	0.992	0.008
K75.0 Abscess of liver	0.000	0.992	0.008
K70.1 Alcoholic hepatitis	0.000	0.992	0.008
C70.9 Meninges, unspecified	0.007	0.992	0.000
C70.1 Spinal meninges	0.007	0.992	0.000
D52 Folate deficiency anaemia	0.008	0.992	0.000
C72.9 Central nervous system, unspecified	0.007	0.992	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.007	0.992	0.000
C72.5 Other and unspecified cranial nerves	0.007	0.992	0.000
C72.4 Acoustic nerve	0.007	0.992	0.000
C72.3 Optic nerve	0.007	0.992	0.000
C72.2 Olfactory nerve	0.007	0.992	0.000
C72.1 Cauda equina	0.007	0.992	0.000
I20.8 Other forms of angina pectoris	0.000	0.992	0.008
M79.67 Pain in limb (Ankle and foot)	0.000	0.992	0.008
I05.0 Mitral stenosis	0.007	0.992	0.000
I20.1 Angina pectoris with documented spasm	0.000	0.992	0.008
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.992	0.007
S82.50 Fracture of medial malleolus (closed)	0.000	0.993	0.007
C15.9 Oesophagus, unspecified	0.000	0.993	0.007
M17.5 Other secondary gonarthrosis	0.000	0.993	0.007
C80.0 Malignant neoplasm, primary site unknown, so stated	0.007	0.993	0.000
M54.56 Low back pain (Lumbar region)	0.007	0.993	0.000
I05.2 Mitral stenosis with insufficiency	0.007	0.993	0.000
D86.1 Sarcoidosis of lymph nodes	0.000	0.993	0.007
I05.8 Other mitral valve diseases	0.006	0.993	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.000	0.993	0.006
C43.3 Malignant melanoma of other and unspecified parts of face	0.007	0.993	0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.006	0.994	0.000
K82.4 Cholesterolosis of gallbladder	0.006	0.994	0.000
C70.0 Cerebral meninges	0.006	0.994	0.000
C72.0 Spinal cord	0.006	0.994	0.000
K74.0 Hepatic fibrosis	0.000	0.994	0.006
M17.4 Other secondary gonarthrosis, bilateral	0.000	0.994	0.006
Z35.1 Supervision of pregnancy with history of abortive outcome	0.000	0.994	0.006
D52.8 Other folate deficiency anaemias	0.006	0.994	0.000
D52.1 Drug-induced folate deficiency anaemia	0.006	0.994	0.000
D52.0 Dietary folate deficiency anaemia	0.006	0.994	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.000	0.994	0.006
K08.3 Retained dental root	0.006	0.994	0.000
R47.0 Dysphasia and aphasia	0.000	0.995	0.005
I67.9 Cerebrovascular disease, unspecified	0.000	0.995	0.005
M17.0 Primary gonarthrosis, bilateral	0.000	0.995	0.005
Z35 Supervision of high-risk pregnancy	0.000	0.995	0.005
M22.4 Chondromalacia patellae	0.000	0.995	0.005
I97.2 Postmastectomy lymphoedema syndrome	0.005	0.995	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.005	0.995	0.000
I51.8 Other ill-defined heart diseases	0.000	0.995	0.005
Z35.0 Supervision of pregnancy with history of infertility	0.000	0.995	0.005
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.000	0.995	0.005
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.005	0.995	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.000	0.995	0.005
M17.3 Other posttraumatic gonarthrosis	0.000	0.995	0.005
Z35.4 Supervision of pregnancy with grand multiparity	0.000	0.995	0.005
M43.1 Spondylolisthesis	0.000	0.995	0.005
I97.1 Other functional disturbances following cardiac surgery	0.005	0.995	0.000
K44 Diaphragmatic hernia	0.004	0.995	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.996	0.004
K70.4 Alcoholic hepatic failure	0.000	0.996	0.004
K70.0 Alcoholic fatty liver	0.000	0.996	0.004
M43.12 Spondylolisthesis (Cervical region)	0.000	0.996	0.004
I67.1 Cerebral aneurysm, nonruptured	0.000	0.996	0.004
Z35.8 Supervision of other high-risk pregnancies	0.000	0.996	0.004
D80-D89 Certain disorders involving the immune mechanism	0.000	0.996	0.004
K44.1 Diaphragmatic hernia with gangrene	0.004	0.996	0.000
I97.0 Postcardiotomy syndrome	0.004	0.996	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.996	0.004
Z35.5 Supervision of elderly primigravida	0.000	0.996	0.004
Z35.7 Supervision of high-risk pregnancy due to social problems	0.000	0.996	0.004
Z35.6 Supervision of very young primigravida	0.000	0.996	0.004
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.000	0.996	0.004
I71 Aortic aneurysm and dissection	0.000	0.996	0.004
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.004	0.996	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.004	0.996	0.000
R94.3 Abnormal results of cardiovascular function studies	0.000	0.996	0.004
K76 Other diseases of liver	0.000	0.996	0.004
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.000	0.996	0.004
M17.1 Other primary gonarthrosis	0.000	0.996	0.004
M43.19 Spondylolisthesis (Site unspecified)	0.000	0.996	0.004
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.996	0.004
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.996	0.004
I97.9 Postprocedural disorder of circulatory system, unspecified	0.004	0.996	0.000
D82 Immunodeficiency associated with other major defects	0.000	0.996	0.004
C15 Malignant neoplasm of oesophagus	0.000	0.996	0.004
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.996	0.004
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.996	0.004
C15.5 Lower third of oesophagus	0.000	0.996	0.004
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.000	0.996	0.004
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.996	0.004
I71.0 Dissection of aorta [any part]	0.000	0.996	0.004
M43.10 Spondylolisthesis (Multiple sites in spine)	0.000	0.996	0.003
D82.1 Di George's syndrome	0.000	0.996	0.003
M20-M25 Other joint disorders	0.000	0.996	0.004
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.000	0.996	0.003
M43.15 Spondylolisthesis (Thoracolumbar region)	0.000	0.996	0.003
M43.13 Spondylolisthesis (Cervicothoracic region)	0.000	0.996	0.003
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.000	0.996	0.003
I07.1 Tricuspid insufficiency	0.000	0.996	0.004
K76.7 Hepatorenal syndrome	0.000	0.996	0.003
M22 Disorders of patella	0.000	0.996	0.003
M43.14 Spondylolisthesis (Thoracic region)	0.000	0.997	0.003
M65 Synovitis and tenosynovitis	0.000	0.997	0.003
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.003	0.997	0.000
M22.3 Other derangements of patella	0.000	0.997	0.003
D84 Other immunodeficiencies	0.000	0.997	0.003
S82.5 Fracture of medial malleolus	0.000	0.997	0.003
D81 Combined immunodeficiencies	0.000	0.997	0.003
M65.2 Calcific tendinitis	0.000	0.997	0.003
D83 Common variable immunodeficiency	0.000	0.997	0.003
M65.3 Trigger finger	0.000	0.997	0.003
M65.34 Trigger finger-Hand	0.000	0.997	0.003
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.997	0.003
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.997	0.003
L29.9 Pruritus, unspecified	0.000	0.997	0.003
D24 Benign neoplasm of breast	0.000	0.997	0.003
I67 Other cerebrovascular diseases	0.000	0.997	0.003
M65.21 Calcific tendinitis (Shoulder region)	0.000	0.997	0.003
C15.1 Thoracic part of oesophagus	0.000	0.997	0.003
K76.5 Hepatic veno-occlusive disease	0.000	0.997	0.003
K76.4 Peliosis hepatis	0.000	0.997	0.003
K76.2 Central haemorrhagic necrosis of liver	0.000	0.997	0.003
K76.1 Chronic passive congestion of liver	0.000	0.997	0.003
D80 Immunodeficiency with predominantly antibody defects	0.000	0.997	0.003
K76.3 Infarction of liver	0.000	0.997	0.003
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.000	0.997	0.003
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.997	0.003
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.997	0.003
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.997	0.003
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.997	0.003
D82.2 Immunodeficiency with short-limbed stature	0.000	0.997	0.003
D82.0 Wiskott-Aldrich syndrome	0.000	0.997	0.003
C15.8 Overlapping lesion of oesophagus	0.000	0.997	0.003
C15.2 Abdominal part of oesophagus	0.000	0.997	0.003
D84.1 Defects in the complement system	0.000	0.997	0.003
K70.9 Alcoholic liver disease, unspecified	0.000	0.997	0.003
O24.9 Diabetes mellitus in pregnancy, unspecified	0.000	0.997	0.003
T91.9 Sequelae of unspecified injury of neck and trunk	0.000	0.997	0.003
M32 Systemic lupus erythematosus	0.000	0.997	0.003
C15.3 Upper third of oesophagus	0.000	0.997	0.003
N76.2 Acute vulvitis	0.000	0.997	0.003
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.997	0.003
M22.1 Recurrent subluxation of patella	0.000	0.997	0.003
O24 Diabetes mellitus in pregnancy	0.000	0.997	0.003
M22.9 Disorder of patella, unspecified	0.000	0.997	0.003
M30 Polyarteritis nodosa and related conditions	0.000	0.997	0.003
R44.3 Hallucinations, unspecified	0.003	0.997	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.997	0.003
H18.4 Corneal degeneration	0.003	0.997	0.000
K76.6 Portal hypertension	0.000	0.997	0.003
I20.0 Unstable angina	0.000	0.997	0.003
H18 Other disorders of cornea	0.003	0.997	0.000
C15.0 Cervical part of oesophagus	0.000	0.997	0.002
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.997	0.002
S82.51 Fracture of medial malleolus (open)	0.000	0.997	0.003
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.997	0.003
D81.9 Combined immunodeficiency, unspecified	0.000	0.997	0.002
D81.8 Other combined immunodeficiencies	0.000	0.997	0.002
D81.7 Major histocompatibility complex class II deficiency	0.000	0.997	0.002
D81.6 Major histocompatibility complex class I deficiency	0.000	0.997	0.002
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.997	0.002
D81.4 Nezelof's syndrome	0.000	0.997	0.002
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.997	0.002
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.997	0.002
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.997	0.002
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.997	0.002
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.000	0.997	0.002
C15.4 Middle third of oesophagus	0.000	0.997	0.003
M65.29 Calcific tendinitis (Site unspecified)	0.000	0.997	0.002
M65.28 Calcific tendinitis (Other)	0.000	0.997	0.002
M65.27 Calcific tendinitis (Ankle and foot)	0.000	0.997	0.002
M65.26 Calcific tendinitis (Lower leg)	0.000	0.997	0.002
M65.25 Calcific tendinitis (Pelvic region and thigh)	0.000	0.997	0.002
M65.24 Calcific tendinitis (Hand)	0.000	0.997	0.002
M65.23 Calcific tendinitis (Forearm)	0.000	0.997	0.002
M65.22 Calcific tendinitis (Upper arm)	0.000	0.997	0.002
M65.20 Calcific tendinitis (Multiple sites)	0.000	0.997	0.002
I69.3 Sequelae of cerebral infarction	0.000	0.997	0.003
M65.38 Trigger finger-Other	0.000	0.997	0.002
M65.37 Trigger finger-Ankle/foot	0.000	0.997	0.002
M65.36 Trigger finger-Lower leg	0.000	0.997	0.002
M65.35 Trigger finger-Pelvic/thigh	0.000	0.997	0.002
M65.33 Trigger finger-Forearm	0.000	0.997	0.002
M65.32 Trigger finger-Upper arm	0.000	0.997	0.002
M65.31 Trigger finger-Shldr region	0.000	0.997	0.002
M65.30 Trigger finger-Mult sites	0.000	0.997	0.002
D83.8 Other common variable immunodeficiencies	0.000	0.997	0.002
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.997	0.002
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.997	0.002
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.997	0.002
S64.4 Injury of digital nerve of other finger	0.003	0.997	0.000
I07 Rheumatic tricuspid valve diseases	0.000	0.997	0.002
H18.2 Other corneal oedema	0.003	0.997	0.000
I67.5 Moyamoya disease	0.000	0.997	0.002
I67.4 Hypertensive encephalopathy	0.000	0.997	0.002
I67.3 Progressive vascular leukoencephalopathy	0.000	0.997	0.002
M65.0 Abscess of tendon sheath	0.000	0.997	0.002
T91.2 Sequelae of other fracture of thorax and pelvis	0.000	0.997	0.002
D83.9 Common variable immunodeficiency, unspecified	0.000	0.997	0.002
D84.9 Immunodeficiency, unspecified	0.000	0.997	0.002
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.997	0.002
M65.1 Other infective (teno)synovitis	0.000	0.997	0.002
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.997	0.002
H18.5 Hereditary corneal dystrophies	0.002	0.997	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.998	0.002
I72.3 Aneurysm of iliac artery	0.000	0.998	0.002
K76.8 Other specified diseases of liver	0.000	0.998	0.002
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.998	0.002
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.998	0.002
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.998	0.002
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.998	0.002
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.998	0.002
T93.0 Sequelae of open wound of lower limb	0.000	0.998	0.002
T91 Sequelae of injuries of neck and trunk	0.000	0.998	0.002
D84.8 Other specified immunodeficiencies	0.000	0.998	0.002
M32.1 Systemic lupus erythematosus with organ or system involvement	0.000	0.998	0.002
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.000	0.998	0.002
M36.3 Arthropathy in other blood disorders	0.000	0.998	0.002
M36.2 Haemophilic arthropathy	0.000	0.998	0.002
M36.1 Arthropathy in neoplastic disease	0.000	0.998	0.002
M36.0 Dermato(poly)myositis in neoplastic disease	0.000	0.998	0.002
C44.1 Skin of eyelid, including canthus	0.002	0.998	0.000
M65.39 Trigger finger-Site unspec	0.000	0.998	0.002
M32.8 Other forms of systemic lupus erythematosus	0.000	0.998	0.002
Y43.1 Antineoplastic antimetabolites	0.000	0.998	0.002
Z30.5 Surveillance of (intra-uterine) contraceptive device	0.002	0.998	0.000
M34 Systemic sclerosis	0.000	0.998	0.002
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.998	0.002
M22.0 Recurrent dislocation of patella	0.000	0.998	0.002
H18.9 Disorder of cornea, unspecified	0.002	0.998	0.000
H18.8 Other specified disorders of cornea	0.002	0.998	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.000	0.998	0.002
T92.1 Sequelae of fracture of arm	0.002	0.998	0.000
C80 Malignant neoplasm without specification of site	0.002	0.998	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.000	0.998	0.002
C34.9 Bronchus or lung, unspecified	0.002	0.998	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.998	0.002
G60.0 Hereditary motor and sensory neuropathy	0.002	0.998	0.000
H18.3 Changes in corneal membranes	0.002	0.998	0.000
H18.0 Corneal pigmentations and deposits	0.002	0.998	0.000
R25.1 Tremor, unspecified	0.000	0.998	0.002
I72 Other aneurysm	0.000	0.998	0.002
M22.10 Recurrent subluxation of patella, unspecified knee	0.000	0.998	0.002
I72.8 Aneurysm of other specified arteries	0.000	0.998	0.002
O24.3 Pre-existing diabetes mellitus, unspecified	0.000	0.998	0.002
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.000	0.998	0.002
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.000	0.998	0.002
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.002	0.998	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.998	0.002
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.000	0.998	0.002
M30.2 Juvenile polyarteritis	0.000	0.998	0.002
M32.0 Drug-induced systemic lupus erythematosus	0.000	0.998	0.002
M47.2 Other spondylosis with radiculopathy	0.002	0.998	0.000
I61 Intracerebral haemorrhage	0.000	0.998	0.002
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.998	0.002
M30.8 Other conditions related to polyarteritis nodosa	0.000	0.998	0.002
R25.3 Fasciculation	0.000	0.998	0.002
W29.9 Unspecified place	0.002	0.998	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.998	0.002
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.998	0.002
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.000	0.998	0.002
I60-I69 Cerebrovascular diseases	0.000	0.998	0.002
H18.1 Bullous keratopathy	0.002	0.998	0.000
S83.2 Tear of meniscus, current	0.000	0.998	0.002
M33 Dermatopolymyositis	0.000	0.998	0.002
H18.6 Keratoconus	0.002	0.998	0.000
M34.0 Progressive systemic sclerosis	0.000	0.998	0.002
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.000	0.998	0.002
I69 Sequelae of cerebrovascular disease	0.000	0.998	0.002
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust	0.000	0.998	0.002
M30.0 Polyarteritis nodosa	0.000	0.998	0.002
Y76.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.002	0.998	0.000
I07.9 Tricuspid valve disease, unspecified	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations