TreeWAS – Variant ID: rs4528684

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.119	0.881
M80-M85 Disorders of bone density and structure	0.118	0.882
M70-M79 Other soft tissue disorders	0.117	0.883
M86-M90 Other osteopathies	0.114	0.886
M85 Other disorders of bone density and structure	0.113	0.887
M24 Other specific joint derangements	0.112	0.888
M05-M14 Inflammatory polyarthropathies	0.112	0.888
M06 Other rheumatoid arthritis	0.111	0.889
M72 Fibroblastic disorders	0.110	0.889
M06.9 Rheumatoid arthritis, unspecified	0.110	0.890
M89 Other disorders of bone	0.109	0.891
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.106	0.894
M79 Other soft tissue disorders, not elsewhere classified	0.106	0.894
M20-M25 Other joint disorders	0.106	0.894
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.105	0.895
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.104	0.896
M85.0 Fibrous dysplasia (monostotic)	0.103	0.897
M24.1 Other articular cartilage disorders	0.102	0.898
M24.0 Loose body in joint	0.102	0.898
M06.0 Seronegative rheumatoid arthritis	0.102	0.898
M80 Osteoporosis with pathological fracture	0.100	0.900
M24.5 Contracture of joint	0.100	0.900
M89.8 Other specified disorders of bone	0.099	0.901
M79.7 Fibromyalgia	0.098	0.902
M24.2 Disorder of ligament	0.098	0.902
M00-M03 Infectious arthropathies	0.097	0.903
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.096	0.904
M89.9 Disorder of bone, unspecified	0.096	0.904
M84 Disorders of continuity of bone	0.096	0.904
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.095	0.905
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.095	0.905
M79.2 Neuralgia and neuritis, unspecified	0.095	0.905
M34 Systemic sclerosis	0.095	0.905
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.094	0.906
M05 Seropositive rheumatoid arthritis	0.093	0.907
M70 Soft tissue disorders related to use, overuse and pressure	0.093	0.907
M85.6 Other cyst of bone	0.093	0.907
M85.8 Other specified disorders of bone density and structure	0.093	0.907
M79.79 Fibromyalgia (Site unspecified)	0.092	0.908
M45-M49 Spondylopathies	0.092	0.908
M60-M63 Disorders of muscles	0.092	0.908
M86 Osteomyelitis	0.092	0.908
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.091	0.909
M82 Osteoporosis in diseases classified elsewhere	0.091	0.909
M80.9 Unspecified osteoporosis with pathological fracture	0.091	0.909
M71 Other bursopathies	0.091	0.909
M24.6 Ankylosis of joint	0.090	0.910
M77 Other enthesopathies	0.089	0.911
M79.5 Residual foreign body in soft tissue	0.088	0.912
M24.07 Loose body in joint (Ankle and foot)	0.088	0.912
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.088	0.912
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.087	0.913
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.087	0.913
M24.8 Other specific joint derangements, not elsewhere classified	0.086	0.914
M24.54 Contracture of joint (Hand)	0.086	0.914
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.085	0.914
M24.23 Disorder of ligament (Forearm)	0.085	0.915
M07 Psoriatic and enteropathic arthropathies	0.085	0.915
M24.13 Other articular cartilage disorders (Forearm)	0.085	0.915
M79.9 Soft tissue disorder, unspecified	0.085	0.915
M83 Adult osteomalacia	0.084	0.915
M79.0 Rheumatism, unspecified	0.084	0.916
M24.01 Loose body in joint (Shoulder region)	0.084	0.916
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.084	0.916
M88 Paget's disease of bone [osteitis deformans]	0.084	0.916
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.084	0.916
M40-M43 Deforming dorsopathies	0.084	0.916
M73 Soft tissue disorders in diseases classified elsewhere	0.084	0.916
M79.28 Neuralgia and neuritis, unspecified (Other)	0.083	0.917
M33 Dermatopolymyositis	0.083	0.917
M24.51 Contracture of joint (Shoulder region)	0.082	0.917
M89.87 Other specified disorders of bone (Ankle and foot)	0.082	0.918
M24.16 Other articular cartilage disorders (Lower leg)	0.082	0.918
M72.2 Plantar fascial fibromatosis	0.082	0.918
M76 Enthesopathies of lower limb, excluding foot	0.081	0.919
M85.9 Disorder of bone density and structure, unspecified	0.081	0.919
M85.5 Aneurysmal bone cyst	0.081	0.919
M85.4 Solitary bone cyst	0.081	0.919
M85.3 Osteitis condensans	0.081	0.919
M85.2 Hyperostosis of skull	0.081	0.919
M85.1 Skeletal fluorosis	0.081	0.919
M34.1 CR(E)ST syndrome	0.081	0.919
M89.86 Other specified disorders of bone (Lower leg)	0.081	0.919
M24.9 Joint derangement, unspecified	0.081	0.919
M24.7 Protrusio acetabuli	0.081	0.919
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.081	0.919
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.081	0.919
M00 Pyogenic arthritis	0.080	0.920
M12 Other specific arthropathies	0.080	0.920
M09 Juvenile arthritis in diseases classified elsewhere	0.080	0.920
M08 Juvenile arthritis	0.080	0.920
M77.9 Enthesopathy, unspecified	0.080	0.920
M06.98 Rheumatoid arthritis, unspecified (Other)	0.080	0.920
M06.8 Other specified rheumatoid arthritis	0.080	0.920
M06.2 Rheumatoid bursitis	0.080	0.920
M06.1 Adult-onset Still's disease	0.080	0.920
M05.9 Seropositive rheumatoid arthritis, unspecified	0.080	0.920
M89.5 Osteolysis	0.080	0.920
M90 Osteopathies in diseases classified elsewhere	0.080	0.920
M84.1 Nonunion of fracture [pseudarthrosis]	0.080	0.920
M72.9 Fibroblastic disorder, unspecified	0.079	0.920
M72.8 Other fibroblastic disorders	0.079	0.920
M72.6 Necrotizing fasciitis	0.079	0.920
M72.5 Fasciitis, not elsewhere classified	0.079	0.920
M72.4 Pseudosarcomatous fibromatosis	0.079	0.920
M72.3 Nodular fasciitis	0.079	0.920
M72.1 Knuckle pads	0.079	0.920
M21 Other acquired deformities of limbs	0.079	0.921
M79.4 Hypertrophy of (infrapatellar) fat pad	0.078	0.921
M89.6 Osteopathy after poliomyelitis	0.078	0.922
M89.4 Other hypertrophic osteo-arthropathy	0.078	0.922
M89.3 Hypertrophy of bone	0.078	0.922
M89.2 Other disorders of bone development and growth	0.078	0.922
M89.1 Epiphyseal arrest	0.078	0.922
M89.0 Algoneurodystrophy	0.078	0.922
M24.02 Loose body in joint (Upper arm)	0.078	0.922
M87 Osteonecrosis	0.078	0.922
M60 Myositis	0.078	0.922
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.078	0.922
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.077	0.923
M80.5 Idiopathic osteoporosis with pathological fracture	0.077	0.923
M89.88 Other specified disorders of bone (Other)	0.076	0.923
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec	0.076	0.924
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other	0.076	0.924
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot	0.076	0.924
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg	0.076	0.924
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh	0.076	0.924
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm	0.076	0.924
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm	0.076	0.924
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region	0.076	0.924
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites	0.076	0.924
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.076	0.924
M65-M68 Disorders of synovium and tendon	0.076	0.924
M79.3 Panniculitis, unspecified	0.076	0.924
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.076	0.924
M85.67 Other cyst of bone (Ankle and foot)	0.076	0.924
M34.9 Systemic sclerosis, unspecified	0.075	0.924
M70.5 Other bursitis of knee	0.075	0.924
M79.70 Fibromyalgia (Multiple sites)	0.075	0.924
M06.3 Rheumatoid nodule	0.075	0.925
M91-M94 Chondropathies	0.075	0.925
M11 Other crystal arthropathies	0.075	0.925
M24.21 Disorder of ligament (Shoulder region)	0.075	0.925
M24.11 Other articular cartilage disorders (Shoulder region)	0.075	0.925
M99 Biomechanical lesions, not elsewhere classified	0.074	0.926
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.074	0.926
M85.08 Fibrous dysplasia (monostotic) (Other)	0.074	0.926
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.074	0.926
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.074	0.926
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.074	0.926
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.074	0.926
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.074	0.926
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.074	0.926
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.074	0.926
M22 Disorders of patella	0.074	0.926
M79.09 Rheumatism, unspecified (Site unspecified)	0.074	0.926
M89.98 Disorder of bone, unspecified (Other)	0.074	0.926
M79.1 Myalgia	0.074	0.926
M24.27 Disorder of ligament (Ankle and foot)	0.074	0.926
M71.2 Synovial cyst of popliteal space [Baker]	0.074	0.926
M24.19 Other articular cartilage disorders (Site unspecified)	0.074	0.926
M24.18 Other articular cartilage disorders (Other)	0.074	0.926
M24.14 Other articular cartilage disorders (Hand)	0.074	0.926
M24.12 Other articular cartilage disorders (Upper arm)	0.074	0.926
M24.10 Other articular cartilage disorders (Multiple sites)	0.074	0.926
M32 Systemic lupus erythematosus	0.074	0.926
M45 Ankylosing spondylitis	0.073	0.926
M24.09 Loose body in joint (Site unspecified)	0.073	0.927
M24.08 Loose body in joint (Other)	0.073	0.927
M24.06 Loose body in joint-Lower leg	0.073	0.927
M24.05 Loose body in joint (Pelvic region and thigh)	0.073	0.927
M24.04 Loose body in joint (Hand)	0.073	0.927
M24.03 Loose body in joint (Forearm)	0.073	0.927
M24.00 Loose body in joint (Multiple sites)	0.073	0.927
M34.8 Other forms of systemic sclerosis	0.073	0.927
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.073	0.927
M06.08 Seronegative rheumatoid arthritis (Other)	0.073	0.927
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.073	0.927
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.073	0.927
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.073	0.927
M06.04 Seronegative rheumatoid arthritis (Hand)	0.073	0.927
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.073	0.927
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.073	0.927
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.073	0.927
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.073	0.927
M24.66 Ankylosis of joint (Lower leg)	0.073	0.927
M86.6 Other chronic osteomyelitis	0.073	0.927
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.072	0.928
M82.1 Osteoporosis in endocrine disorders	0.072	0.928
M80.8 Other osteoporosis with pathological fracture	0.072	0.928
M80.4 Drug-induced osteoporosis with pathological fracture	0.072	0.928
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.072	0.928
M80.2 Osteoporosis of disuse with pathological fracture	0.072	0.928
M24.59 Contracture of joint (Site unspecified)	0.072	0.928
M24.58 Contracture of joint (Other)	0.072	0.928
M24.57 Contracture of joint (Ankle and foot)	0.072	0.928
M24.56 Contracture of joint (Lower leg)	0.072	0.928
M24.55 Contracture of joint (Pelvic region and thigh)	0.072	0.928
M24.53 Contracture of joint (Forearm)	0.072	0.928
M24.52 Contracture of joint (Upper arm)	0.072	0.928
M24.50 Contracture of joint (Multiple sites)	0.072	0.928
M84.0 Malunion of fracture	0.072	0.928
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.072	0.928
M89.89 Other specified disorders of bone (Site unspecified)	0.071	0.929
M89.84 Other specified disorders of bone (Hand)	0.071	0.929
M89.83 Other specified disorders of bone (Forearm)	0.071	0.929
M89.82 Other specified disorders of bone (Upper arm)	0.071	0.929
M89.81 Other specified disorders of bone (Shoulder region)	0.071	0.929
M89.80 Other specified disorders of bone (Multiple sites)	0.071	0.929
M30 Polyarteritis nodosa and related conditions	0.071	0.929
M70.3 Other bursitis of elbow	0.071	0.929
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.071	0.929
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.071	0.929
M79.78 Fibromyalgia (Other)	0.071	0.929
M79.77 Fibromyalgia (Ankle and foot)	0.071	0.929
M79.76 Fibromyalgia (Lower leg)	0.071	0.929
M79.75 Fibromyalgia (Pelvic region and thigh)	0.071	0.929
M79.74 Fibromyalgia (Hand)	0.071	0.929
M79.73 Fibromyalgia (Forearm)	0.071	0.929
M79.72 Fibromyalgia (Upper arm)	0.071	0.929
M79.71 Fibromyalgia (Shoulder region)	0.071	0.929
M49 Spondylopathies in diseases classified elsewhere	0.071	0.929
M79.57 Residual foreign body in soft tissue (Ankle and foot)	0.071	0.929
M85.65 Other cyst of bone (Pelvic region and thigh)	0.070	0.929
M24.24 Disorder of ligament (Hand)	0.070	0.930
M24.29 Disorder of ligament (Site unspecified)	0.070	0.930
M24.28 Disorder of ligament (Other)	0.070	0.930
M24.25 Disorder of ligament (Pelvic region and thigh)	0.070	0.930
M24.22 Disorder of ligament (Upper arm)	0.070	0.930
M24.20 Disorder of ligament (Multiple sites)	0.070	0.930
M79.54 Residual foreign body in soft tissue (Hand)	0.070	0.930
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.070	0.930
M86.8 Other osteomyelitis	0.070	0.930
M70.7 Other bursitis of hip	0.070	0.930
M89.96 Disorder of bone, unspecified (Lower leg)	0.069	0.930
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.069	0.930
M02 Reactive arthropathies	0.069	0.930
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.069	0.930
M81 Osteoporosis without pathological fracture	0.069	0.931
M89.99 Disorder of bone, unspecified (Site unspecified)	0.069	0.931
M89.93 Disorder of bone, unspecified (Forearm)	0.069	0.931
M89.92 Disorder of bone, unspecified (Upper arm)	0.069	0.931
M89.91 Disorder of bone, unspecified (Shoulder region)	0.069	0.931
M89.90 Disorder of bone, unspecified (Multiple sites)	0.069	0.931
M85.88 Other specified disorders of bone density and structure (Other)	0.069	0.931
M84.9 Disorder of continuity of bone, unspecified	0.069	0.931
M84.8 Other disorders of continuity of bone	0.069	0.931
M84.3 Stress fracture, not elsewhere classified	0.069	0.931
M84.2 Delayed union of fracture	0.069	0.931
M00.9 Pyogenic arthritis, unspecified	0.069	0.931
M70.4 Prepatellar bursitis	0.069	0.931
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.069	0.931
M10 Gout	0.069	0.931
M79.94 Soft tissue disorder, unspecified (Hand)	0.068	0.932
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)	0.068	0.932
M79.24 Neuralgia and neuritis, unspecified (Hand)	0.068	0.932
M79.23 Neuralgia and neuritis, unspecified (Forearm)	0.068	0.932
M79.22 Neuralgia and neuritis, unspecified (Upper arm)	0.068	0.932
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)	0.068	0.932
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)	0.068	0.932
M77.91 Enthesopathy, unspecified (Shoulder region)	0.068	0.932
M34.2 Systemic sclerosis induced by drugs and chemicals	0.068	0.932
M34.0 Progressive systemic sclerosis	0.068	0.932
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.068	0.932
M89.94 Disorder of bone, unspecified (Hand)	0.068	0.932
M24.4 Recurrent dislocation and subluxation of joint	0.067	0.932
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.067	0.932
M14 Arthropathies in other diseases classified elsewhere	0.067	0.933
M22.8 Other disorders of patella	0.067	0.933
M25 Other joint disorders, not elsewhere classified	0.067	0.933
M05.8 Other seropositive rheumatoid arthritis	0.067	0.933
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.067	0.933
M05.2 Rheumatoid vasculitis	0.067	0.933
M05.1 Rheumatoid lung disease	0.067	0.933
M05.0 Felty's syndrome	0.067	0.933
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure	0.067	0.933
M70.8 Other soft tissue disorders related to use, overuse and pressure	0.067	0.933
M70.1 Bursitis of hand	0.067	0.933
M70.0 Chronic crepitant synovitis of hand and wrist	0.067	0.933
M24.67 Ankylosis of joint (Ankle and foot)	0.067	0.933
M33.1 Other dermatomyositis	0.067	0.933
M47 Spondylosis	0.067	0.933
M84.4 Pathological fracture, not elsewhere classified	0.067	0.933
M85.69 Other cyst of bone (Site unspecified)	0.066	0.933
M85.68 Other cyst of bone (Other)	0.066	0.933
M85.66 Other cyst of bone (Lower leg)	0.066	0.933
M85.64 Other cyst of bone (Hand)	0.066	0.933
M85.63 Other cyst of bone (Forearm)	0.066	0.933
M85.62 Other cyst of bone (Upper arm)	0.066	0.933
M85.61 Other cyst of bone (Shoulder region)	0.066	0.933
M85.60 Other cyst of bone (Multiple sites)	0.066	0.933
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.066	0.933
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.066	0.933
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.066	0.933
M85.84 Other specified disorders of bone density and structure (Hand)	0.066	0.933
M85.83 Other specified disorders of bone density and structure (Forearm)	0.066	0.933
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.066	0.933
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.066	0.933
M07.3 Other psoriatic arthropathies	0.066	0.934
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.066	0.934
M63 Disorders of muscle in diseases classified elsewhere	0.066	0.934
M61 Calcification and ossification of muscle	0.066	0.934
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.066	0.934
M86.9 Osteomyelitis, unspecified	0.066	0.934
M86.5 Other chronic haematogenous osteomyelitis	0.066	0.934
M86.4 Chronic osteomyelitis with draining sinus	0.066	0.934
M86.3 Chronic multifocal osteomyelitis	0.066	0.934
M86.2 Subacute osteomyelitis	0.066	0.934
M86.1 Other acute osteomyelitis	0.066	0.934
M86.0 Acute haematogenous osteomyelitis	0.066	0.934
M82.8 Osteoporosis in other diseases classified elsewhere	0.065	0.934
M82.0 Osteoporosis in multiple myelomatosis	0.065	0.934
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.065	0.934
M21.0 Valgus deformity, not elsewhere classified	0.065	0.934
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.065	0.935
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.065	0.935
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.065	0.935
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.065	0.935
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.065	0.935
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.065	0.935
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.065	0.935
M71.9 Bursopathy, unspecified	0.065	0.935
M71.8 Other specified bursopathies	0.065	0.935
M71.5 Other bursitis, not elsewhere classified	0.065	0.935
M71.4 Calcium deposit in bursa	0.065	0.935
M71.1 Other infective bursitis	0.065	0.935
M71.0 Abscess of bursa	0.065	0.935
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.065	0.935
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.065	0.935
M24.69 Ankylosis of joint (Site unspecified)	0.065	0.935
M24.68 Ankylosis of joint (Other)	0.065	0.935
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.065	0.935
M24.64 Ankylosis of joint (Hand)	0.065	0.935
M24.63 Ankylosis of joint (Forearm)	0.065	0.935
M24.62 Ankylosis of joint (Upper arm)	0.065	0.935
M24.61 Ankylosis of joint (Shoulder region)	0.065	0.935
M24.60 Ankylosis of joint (Multiple sites)	0.065	0.935
M24.26 Disorder of ligament (Lower leg)	0.065	0.935
M80.0 Postmenopausal osteoporosis with pathological fracture	0.065	0.935
M60.9 Myositis, unspecified	0.064	0.936
M77.8 Other enthesopathies, not elsewhere classified	0.064	0.936
M77.3 Calcaneal spur	0.064	0.936
M77.2 Periarthritis of wrist	0.064	0.936
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.064	0.936
M48 Other spondylopathies	0.064	0.936
M21.2 Flexion deformity	0.063	0.936
M77.4 Metatarsalgia	0.063	0.937
M79.59 Residual foreign body in soft tissue (Site unspecified)	0.063	0.937
M79.58 Residual foreign body in soft tissue (Other)	0.063	0.937
M79.56 Residual foreign body in soft tissue (Lower leg)	0.063	0.937
M79.55 Residual foreign body in soft tissue (Pelvic region and thigh)	0.063	0.937
M79.53 Residual foreign body in soft tissue (Forearm)	0.063	0.937
M79.52 Residual foreign body in soft tissue (Upper arm)	0.063	0.937
M79.51 Residual foreign body in soft tissue (Shoulder region)	0.063	0.937
M79.50 Residual foreign body in soft tissue (Multiple sites)	0.063	0.937
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.063	0.937
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.063	0.937
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.063	0.937
M70.56 Other bursitis of knee-Lower Leg	0.063	0.937
M76.8 Other enthesopathies of lower limb, excluding foot	0.063	0.937
M79.96 Soft tissue disorder, unspecified (Lower leg)	0.063	0.937
M77.94 Enthesopathy, unspecified (Hand)	0.063	0.937
M88.9 Paget's disease of bone, unspecified	0.063	0.937
M71.3 Other bursal cyst	0.062	0.937
M70.2 Olecranon bursitis	0.062	0.937
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.062	0.938
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.062	0.938
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.062	0.938
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.062	0.938
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.062	0.938
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.062	0.938
M60.0 Infective myositis	0.061	0.938
M46 Other inflammatory spondylopathies	0.061	0.939
M07.6 Other enteropathic arthropathies	0.061	0.939
M07.5 Arthropathy in ulcerative colitis	0.061	0.939
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.061	0.939
M07.2 Psoriatic spondylitis	0.061	0.939
M07.1 Arthritis mutilans	0.061	0.939
M07.0 Distal interphalangeal psoriatic arthropathy	0.061	0.939
M43 Other deforming dorsopathies	0.061	0.939
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.061	0.939
M79.99 Soft tissue disorder, unspecified (Site unspecified)	0.061	0.939
M79.98 Soft tissue disorder, unspecified (Other)	0.061	0.939
M79.97 Soft tissue disorder, unspecified (Ankle and foot)	0.061	0.939
M79.95 Soft tissue disorder, unspecified (Pelvic region and thigh)	0.061	0.939
M79.93 Soft tissue disorder, unspecified (Forearm)	0.061	0.939
M79.92 Soft tissue disorder, unspecified (Upper arm)	0.061	0.939
M79.91 Soft tissue disorder, unspecified (Shoulder region)	0.061	0.939
M79.90 Soft tissue disorder, unspecified (Multiple sites)	0.061	0.939
M83.9 Adult osteomalacia, unspecified	0.061	0.939
M83.8 Other adult osteomalacia	0.061	0.939
M83.5 Other drug-induced osteomalacia in adults	0.061	0.939
M83.4 Aluminum bone disease	0.061	0.939
M83.3 Adult osteomalacia due to malnutrition	0.061	0.939
M83.2 Adult osteomalacia due to malabsorption	0.061	0.939
M83.1 Senile osteomalacia	0.061	0.939
M83.0 Puerperal osteomalacia	0.061	0.939
M77.0 Medial epicondylitis	0.061	0.939
M70.6 Trochanteric bursitis	0.061	0.939
M79.08 Rheumatism, unspecified (Other)	0.061	0.939
M79.07 Rheumatism, unspecified (Ankle and foot)	0.061	0.939
M79.06 Rheumatism, unspecified (Lower leg)	0.061	0.939
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.061	0.939
M79.04 Rheumatism, unspecified (Hand)	0.061	0.939
M79.03 Rheumatism, unspecified (Forearm)	0.061	0.939
M79.02 Rheumatism, unspecified (Upper arm)	0.061	0.939
M79.01 Rheumatism, unspecified (Shoulder region)	0.061	0.939
M88.8 Paget's disease of other bones	0.060	0.939
M88.0 Paget's disease of skull	0.060	0.939
M42 Spinal osteochondrosis	0.060	0.940
M73.8 Other soft tissue disorders in diseases classified elsewhere	0.060	0.940
M73.1 Syphilitic bursitis	0.060	0.940
M73.0 Gonococcal bursitis	0.060	0.940
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.060	0.940
M33.2 Polymyositis	0.060	0.940
M77.5 Other enthesopathy of foot	0.060	0.940
M21.7 Unequal limb length (acquired)	0.060	0.940
M33.9 Dermatopolymyositis, unspecified	0.060	0.940
M33.0 Juvenile dermatomyositis	0.060	0.940
M41 Scoliosis	0.059	0.940
M99.8 Other biomechanical lesions	0.059	0.941
M86.67 Other chronic osteomyelitis (Ankle and foot)	0.059	0.941
M79.46 Hypertrophy of (infrapatellar) fat pad (Lower leg)	0.059	0.941
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.059	0.941
M24.17 Other articular cartilage disorders (Ankle and foot)	0.059	0.941
M87.8 Other osteonecrosis	0.059	0.941
M40 Kyphosis and lordosis	0.059	0.941
M72.29 Plantar fascial fibromatosis-Site unspec	0.059	0.941
M72.28 Plantar fascial fibromatosis-Other	0.059	0.941
M72.26 Plantar fascial fibromatosis-Lower Leg	0.059	0.941
M72.25 Plantar fascial fibromatosis-Pelvic/Thigh	0.059	0.941
M72.24 Plantar fascial fibromatosis-Hand	0.059	0.941
M72.23 Plantar fascial fibromatosis-Forearm	0.059	0.941
M72.22 Plantar fascial fibromatosis-Upper arm	0.059	0.941
M72.21 Plantar fascial fibromatosis-Shldr region	0.059	0.941
M72.20 Plantar fascial fibromatosis-Mult sites	0.059	0.941
M79.16 Myalgia (Lower leg)	0.059	0.941
M47.9 Spondylosis, unspecified	0.059	0.941
M89.55 Osteolysis (Pelvic region and thigh)	0.059	0.941
M21.4 Flat foot [pes planus] (acquired)	0.058	0.941
M76.9 Enthesopathy of lower limb, unspecified	0.058	0.942
M76.7 Peroneal tendinitis	0.058	0.942
M76.5 Patellar tendinitis	0.058	0.942
M76.4 Tibial collateral bursitis [Pellegrini-Stieda]	0.058	0.942
M76.3 Iliotibial band syndrome	0.058	0.942
M76.2 Iliac crest spur	0.058	0.942
M76.1 Psoas tendinitis	0.058	0.942
M76.0 Gluteal tendinitis	0.058	0.942
M85.19 Skeletal fluorosis (Site unspecified)	0.058	0.942
M85.18 Skeletal fluorosis (Other)	0.058	0.942
M85.17 Skeletal fluorosis (Ankle and foot)	0.058	0.942
M85.16 Skeletal fluorosis (Lower leg)	0.058	0.942
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.058	0.942
M85.14 Skeletal fluorosis (Hand)	0.058	0.942
M85.13 Skeletal fluorosis (Forearm)	0.058	0.942
M85.12 Skeletal fluorosis (Upper arm)	0.058	0.942
M85.11 Skeletal fluorosis (Shoulder region)	0.058	0.942
M85.10 Skeletal fluorosis (Multiple sites)	0.058	0.942
M85.29 Hyperostosis of skull-Site unspec	0.058	0.942
M85.28 Hyperostosis of skull-Other	0.058	0.942
M85.27 Hyperostosis of skull-Ankle/Foot	0.058	0.942
M85.26 Hyperostosis of skull-Lower Leg	0.058	0.942
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.058	0.942
M85.24 Hyperostosis of skull-Hand	0.058	0.942
M85.23 Hyperostosis of skull-Forearm	0.058	0.942
M85.22 Hyperostosis of skull-Upper arm	0.058	0.942
M85.21 Hyperostosis of skull-Shldr region	0.058	0.942
M85.20 Hyperostosis of skull-Mult sites	0.058	0.942
M85.39 Osteitis condensans (Site unspecified)	0.058	0.942
M85.38 Osteitis condensans (Other)	0.058	0.942
M85.37 Osteitis condensans (Ankle and foot)	0.058	0.942
M85.36 Osteitis condensans (Lower leg)	0.058	0.942
M85.35 Osteitis condensans (Pelvic region and thigh)	0.058	0.942
M85.34 Osteitis condensans (Hand)	0.058	0.942
M85.33 Osteitis condensans (Forearm)	0.058	0.942
M85.32 Osteitis condensans (Upper arm)	0.058	0.942
M85.31 Osteitis condensans (Shoulder region)	0.058	0.942
M85.30 Osteitis condensans (Multiple sites)	0.058	0.942
M85.49 Solitary bone cyst (Site unspecified)	0.058	0.942
M85.48 Solitary bone cyst (Other)	0.058	0.942
M85.47 Solitary bone cyst (Ankle and foot)	0.058	0.942
M85.46 Solitary bone cyst (Lower leg)	0.058	0.942
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.058	0.942
M85.44 Solitary bone cyst (Hand)	0.058	0.942
M85.43 Solitary bone cyst (Forearm)	0.058	0.942
M85.42 Solitary bone cyst (Upper arm)	0.058	0.942
M85.41 Solitary bone cyst (Shoulder region)	0.058	0.942
M85.40 Solitary bone cyst (Multiple sites)	0.058	0.942
M85.59 Aneurysmal bone cyst (Site unspecified)	0.058	0.942
M85.58 Aneurysmal bone cyst (Other)	0.058	0.942
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.058	0.942
M85.56 Aneurysmal bone cyst (Lower leg)	0.058	0.942
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.058	0.942
M85.54 Aneurysmal bone cyst (Hand)	0.058	0.942
M85.53 Aneurysmal bone cyst (Forearm)	0.058	0.942
M85.52 Aneurysmal bone cyst (Upper arm)	0.058	0.942
M85.51 Aneurysmal bone cyst (Shoulder region)	0.058	0.942
M85.50 Aneurysmal bone cyst (Multiple sites)	0.058	0.942
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.058	0.942
M85.98 Disorder of bone density and structure, unspecified (Other)	0.058	0.942

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations