TreeWAS – Variant ID: rs4540292

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	0.000	0.000	1.000
L40.5 Arthropathic psoriasis	0.000	0.000	1.000
L40 Psoriasis	0.000	0.000	1.000
I20 Angina pectoris	1.000	0.000	0.000
I20.9 Angina pectoris, unspecified	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	1.000	0.000	0.000
Z95.1 Presence of aortocoronary bypass graft	0.997	0.003	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.997	0.003	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.007	0.993
I20.0 Unstable angina	0.993	0.007	0.000
M07.3 Other psoriatic arthropathies	0.000	0.008	0.992
R31 Unspecified haematuria	0.989	0.011	0.000
L40.0 Psoriasis vulgaris	0.000	0.014	0.986
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.016	0.984
Z95.5 Presence of coronary angioplasty implant and graft	0.982	0.018	0.000
I25.2 Old myocardial infarction	0.976	0.024	0.000
Z95.0 Presence of cardiac pacemaker	0.976	0.024	0.000
Z95.3 Presence of xenogenic heart valve	0.971	0.029	0.000
I22 Subsequent myocardial infarction	0.959	0.041	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.945	0.055	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.943	0.057	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.106	0.894
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.146	0.854
I25.5 Ischaemic cardiomyopathy	0.850	0.149	0.000
L40.3 Pustulosis palmaris et plantaris	0.000	0.165	0.835
L40.1 Generalised pustular psoriasis	0.000	0.168	0.832
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.172	0.828
G35 Multiple sclerosis	0.000	0.189	0.811
I21 Acute myocardial infarction	0.809	0.191	0.000
Z95.2 Presence of prosthetic heart valve	0.800	0.200	0.000
I20.1 Angina pectoris with documented spasm	0.798	0.202	0.000
E78.0 Pure hypercholesterolaemia	0.787	0.213	0.000
I21.9 Acute myocardial infarction, unspecified	0.784	0.216	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.769	0.231	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.234	0.766
I25.4 Coronary artery aneurysm	0.747	0.253	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.745	0.255	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.720	0.280	0.000
L40.2 Acrodermatitis continua	0.000	0.283	0.717
I25.6 Silent myocardial ischaemia	0.717	0.283	0.000
L40.8 Other psoriasis	0.000	0.284	0.716
L40.4 Guttate psoriasis	0.000	0.284	0.716
M07.38 Other psoriatic arthropathies (Other)	0.000	0.289	0.711
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.289	0.711
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.289	0.711
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.289	0.711
I23 Certain current complications following acute myocardial infarction	0.697	0.303	0.000
I22.8 Subsequent myocardial infarction of other sites	0.665	0.335	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.631	0.369	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.616	0.384	0.000
I25.3 Aneurysm of heart	0.611	0.389	0.000
M07 Psoriatic and enteropathic arthropathies	0.192	0.393	0.415
I21.2 Acute transmural myocardial infarction of other sites	0.601	0.399	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.580	0.420	0.000
Z95.4 Presence of other heart-valve replacement	0.563	0.437	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.514	0.486	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.493	0.507
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.502	0.498	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.500	0.500	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.500	0.500	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.500	0.500	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.500	0.500	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.500	0.500	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.500	0.500	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.500	0.500	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.499	0.501	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.497	0.503	0.000
M05 Seropositive rheumatoid arthritis	0.491	0.509	0.000
I23.8 Other current complications following acute myocardial infarction	0.479	0.520	0.000
M06 Other rheumatoid arthritis	0.463	0.537	0.000
M05-M14 Inflammatory polyarthropathies	0.460	0.538	0.001
M06.9 Rheumatoid arthritis, unspecified	0.455	0.545	0.000
M06.3 Rheumatoid nodule	0.454	0.546	0.000
M45 Ankylosing spondylitis	0.000	0.547	0.453
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.447	0.553	0.000
M06.34 Rheumatoid nodule (Hand)	0.445	0.555	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.561	0.439
M07.6 Other enteropathic arthropathies	0.138	0.564	0.298
M07.5 Arthropathy in ulcerative colitis	0.138	0.564	0.298
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.138	0.564	0.298
M07.2 Psoriatic spondylitis	0.138	0.564	0.298
M07.1 Arthritis mutilans	0.138	0.564	0.298
M07.0 Distal interphalangeal psoriatic arthropathy	0.138	0.564	0.298
K90 Intestinal malabsorption	0.000	0.568	0.432
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.429	0.571	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.421	0.579	0.000
I20.8 Other forms of angina pectoris	0.412	0.588	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.410	0.589	0.001
M05.1 Rheumatoid lung disease	0.407	0.592	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.407	0.592	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.400	0.600	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.392	0.608	0.000
D86 Sarcoidosis	0.000	0.614	0.386
M06.98 Rheumatoid arthritis, unspecified (Other)	0.377	0.623	0.000
D80-D89 Certain disorders involving the immune mechanism	0.000	0.623	0.377
M06.32 Rheumatoid nodule (Upper arm)	0.376	0.624	0.000
D86.0 Sarcoidosis of lung	0.000	0.625	0.375
M05.8 Other seropositive rheumatoid arthritis	0.374	0.625	0.000
M12 Other specific arthropathies	0.371	0.629	0.001
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.368	0.632	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.368	0.632	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.635	0.365
I22.0 Subsequent myocardial infarction of anterior wall	0.363	0.636	0.001
D86.9 Sarcoidosis, unspecified	0.000	0.639	0.361
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.642	0.358
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.357	0.643	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.355	0.645	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.352	0.648	0.000
M05.0 Felty's syndrome	0.352	0.648	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.650	0.350
M05.19 Rheumatoid lung disease (Site unspecified)	0.348	0.652	0.000
M11 Other crystal arthropathies	0.345	0.654	0.001
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.345	0.655	0.000
M08 Juvenile arthritis	0.342	0.656	0.001
M06.37 Rheumatoid nodule (Ankle and foot)	0.342	0.658	0.000
M05.2 Rheumatoid vasculitis	0.341	0.658	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.661	0.339
M06.8 Other specified rheumatoid arthritis	0.336	0.664	0.000
D86.3 Sarcoidosis of skin	0.000	0.665	0.335
M06.2 Rheumatoid bursitis	0.332	0.668	0.000
M06.1 Adult-onset Still's disease	0.332	0.668	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.330	0.669	0.001
M06.39 Rheumatoid nodule (Site unspecified)	0.326	0.674	0.000
M06.38 Rheumatoid nodule (Other)	0.326	0.674	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.326	0.674	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.326	0.674	0.000
M06.33 Rheumatoid nodule (Forearm)	0.326	0.674	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.326	0.674	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.675	0.325
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.675	0.325
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.675	0.325
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.675	0.325
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.675	0.325
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.675	0.325
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.675	0.325
D80 Immunodeficiency with predominantly antibody defects	0.000	0.679	0.321
D86.1 Sarcoidosis of lymph nodes	0.000	0.679	0.320
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.318	0.682	0.000
M14 Arthropathies in other diseases classified elsewhere	0.312	0.686	0.001
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.313	0.687	0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.099	0.687	0.213
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.099	0.687	0.213
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.099	0.687	0.213
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.099	0.687	0.213
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.099	0.687	0.213
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.099	0.687	0.213
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.099	0.687	0.213
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.099	0.687	0.213
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.099	0.687	0.213
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.099	0.687	0.213
M07.19 Arthritis mutilans (Site unspecified)	0.099	0.687	0.213
M07.18 Arthritis mutilans (Other)	0.099	0.687	0.213
M07.17 Arthritis mutilans (Ankle and foot)	0.099	0.687	0.213
M07.16 Arthritis mutilans (Lower leg)	0.099	0.687	0.213
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.099	0.687	0.213
M07.14 Arthritis mutilans (Hand)	0.099	0.687	0.213
M07.13 Arthritis mutilans (Forearm)	0.099	0.687	0.213
M07.12 Arthritis mutilans (Upper arm)	0.099	0.687	0.213
M07.11 Arthritis mutilans (Shoulder region)	0.099	0.687	0.213
M07.10 Arthritis mutilans (Multiple sites)	0.099	0.687	0.213
M07.29 Psoriatic spondylitis (Site unspecified)	0.099	0.687	0.213
M07.28 Psoriatic spondylitis (Other)	0.099	0.687	0.213
M07.27 Psoriatic spondylitis (Ankle and foot)	0.099	0.687	0.213
M07.26 Psoriatic spondylitis (Lower leg)	0.099	0.687	0.213
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.099	0.687	0.213
M07.24 Psoriatic spondylitis (Hand)	0.099	0.687	0.213
M07.23 Psoriatic spondylitis (Forearm)	0.099	0.687	0.213
M07.22 Psoriatic spondylitis (Upper arm)	0.099	0.687	0.213
M07.21 Psoriatic spondylitis (Shoulder region)	0.099	0.687	0.213
M07.20 Psoriatic spondylitis (Multiple sites)	0.099	0.687	0.213
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.099	0.687	0.213
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.099	0.687	0.213
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.099	0.687	0.213
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.099	0.687	0.213
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.099	0.687	0.213
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.099	0.687	0.213
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.099	0.687	0.213
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.099	0.687	0.213
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.099	0.687	0.213
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.099	0.687	0.213
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.099	0.687	0.213
M07.58 Arthropathy in ulcerative colitis (Other)	0.099	0.687	0.213
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.099	0.687	0.213
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.099	0.687	0.213
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.099	0.687	0.213
M07.54 Arthropathy in ulcerative colitis (Hand)	0.099	0.687	0.213
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.099	0.687	0.213
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.099	0.687	0.213
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.099	0.687	0.213
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.099	0.687	0.213
M07.69 Other enteropathic arthropathies (Site unspecified)	0.099	0.687	0.213
M07.68 Other enteropathic arthropathies (Other)	0.099	0.687	0.213
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.099	0.687	0.213
M07.66 Other enteropathic arthropathies (Lower leg)	0.099	0.687	0.213
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.099	0.687	0.213
M07.64 Other enteropathic arthropathies (Hand)	0.099	0.687	0.213
M07.63 Other enteropathic arthropathies (Forearm)	0.099	0.687	0.213
M07.62 Other enteropathic arthropathies (Upper arm)	0.099	0.687	0.213
M07.61 Other enteropathic arthropathies (Shoulder region)	0.099	0.687	0.213
M07.60 Other enteropathic arthropathies (Multiple sites)	0.099	0.687	0.213
K90.3 Pancreatic steatorrhoea	0.000	0.690	0.310
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.690	0.310
K90.1 Tropical sprue	0.000	0.690	0.310
I24 Other acute ischaemic heart diseases	0.309	0.691	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.309	0.691	0.000
M12.3 Palindromic rheumatism	0.303	0.696	0.001
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.697	0.303
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.699	0.301
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.299	0.701	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.703	0.297
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.704	0.296
M05.18 Rheumatoid lung disease (Other)	0.292	0.707	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.292	0.707	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.292	0.707	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.292	0.707	0.000
M05.14 Rheumatoid lung disease (Hand)	0.292	0.707	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.292	0.707	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.292	0.707	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.292	0.707	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.292	0.707	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.291	0.709	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.288	0.712	0.000
D70 Agranulocytosis	0.000	0.718	0.282
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.280	0.720	0.000
M11.2 Other chondrocalcinosis	0.279	0.720	0.001
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.721	0.279
K90.8 Other intestinal malabsorption	0.000	0.722	0.278
D50-D53 Nutritional anaemias	0.000	0.725	0.275
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.727	0.273
D86.8 Sarcoidosis of other and combined sites	0.000	0.729	0.271
M12.5 Traumatic arthropathy	0.270	0.729	0.001
M12.8 Other specific arthropathies, not elsewhere classified	0.270	0.729	0.001
D81 Combined immunodeficiencies	0.000	0.730	0.270
D89.1 Cryoglobulinaemia	0.000	0.731	0.269
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.268	0.731	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.268	0.731	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.268	0.731	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.268	0.731	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.268	0.731	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.268	0.731	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.268	0.731	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.268	0.731	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.268	0.731	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.731	0.268
D83 Common variable immunodeficiency	0.000	0.733	0.267
M12.4 Intermittent hydrarthrosis	0.266	0.733	0.001
M12.1 Kaschin-Beck disease	0.266	0.733	0.001
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.266	0.733	0.001
D51 Vitamin B12 deficiency anaemia	0.000	0.734	0.266
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.734	0.266
M12.2 Villonodular synovitis (pigmented)	0.262	0.737	0.001
D89.3 Immune reconstitution syndrome	0.000	0.738	0.262
M08.0 Juvenile rheumatoid arthritis	0.258	0.741	0.001
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.743	0.257
M06.4 Inflammatory polyarthropathy	0.257	0.743	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.256	0.743	0.001
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.747	0.253
M05.09 Felty's syndrome (Site unspecified)	0.252	0.747	0.000
M05.08 Felty's syndrome (Other)	0.252	0.747	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.252	0.747	0.000
M05.06 Felty's syndrome (Lower leg)	0.252	0.747	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.252	0.747	0.000
M05.04 Felty's syndrome (Hand)	0.252	0.747	0.000
M05.03 Felty's syndrome (Forearm)	0.252	0.747	0.000
M05.02 Felty's syndrome (Upper arm)	0.252	0.747	0.000
M05.01 Felty's syndrome (Shoulder region)	0.252	0.747	0.000
M05.00 Felty's syndrome (Multiple sites)	0.252	0.747	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.252	0.747	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.252	0.747	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.252	0.747	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.252	0.747	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.252	0.747	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.252	0.747	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.252	0.747	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.252	0.747	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.252	0.747	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.252	0.747	0.000
D72 Other disorders of white blood cells	0.000	0.748	0.252
M06.0 Seronegative rheumatoid arthritis	0.249	0.751	0.000
D84 Other immunodeficiencies	0.000	0.751	0.248
M11.1 Familial chondrocalcinosis	0.247	0.752	0.001
M11.0 Hydroxyapatite deposition disease	0.247	0.752	0.001
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.752	0.248
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.246	0.753	0.000
M08.9 Juvenile arthritis, unspecified	0.246	0.753	0.001
M08.8 Other juvenile arthritis	0.246	0.753	0.001
M08.4 Pauciarticular juvenile arthritis	0.246	0.753	0.001
M08.3 Juvenile polyarthritis (seronegative)	0.246	0.753	0.001
M08.2 Juvenile arthritis with systemic onset	0.246	0.753	0.001
M08.1 Juvenile ankylosing spondylitis	0.246	0.753	0.001
M05.28 Rheumatoid vasculitis (Other)	0.245	0.755	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.245	0.755	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.245	0.755	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.245	0.755	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.245	0.755	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.245	0.755	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.245	0.755	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.245	0.755	0.000
M12.30 Palindromic rheumatism (Multiple sites)	0.242	0.757	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.241	0.759	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.241	0.759	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.241	0.759	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.241	0.759	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.241	0.759	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.241	0.759	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.241	0.759	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.241	0.759	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.241	0.759	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.759	0.241
D82 Immunodeficiency associated with other major defects	0.000	0.760	0.240
M05.20 Rheumatoid vasculitis (Multiple sites)	0.239	0.761	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.239	0.761	0.000
D53 Other nutritional anaemias	0.000	0.761	0.239
M06.19 Adult-onset Still's disease (Site unspecified)	0.238	0.762	0.000
M06.18 Adult-onset Still's disease (Other)	0.238	0.762	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.238	0.762	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.238	0.762	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.238	0.762	0.000
M06.14 Adult-onset Still's disease (Hand)	0.238	0.762	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.238	0.762	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.238	0.762	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.238	0.762	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.238	0.762	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.238	0.762	0.000
M06.28 Rheumatoid bursitis (Other)	0.238	0.762	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.238	0.762	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.238	0.762	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.238	0.762	0.000
M06.24 Rheumatoid bursitis (Hand)	0.238	0.762	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.238	0.762	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.238	0.762	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.238	0.762	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.238	0.762	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.237	0.762	0.001
M09.2 Juvenile arthritis in ulcerative colitis	0.237	0.762	0.001
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.237	0.762	0.001
M09.0 Juvenile arthritis in psoriasis	0.237	0.762	0.001
I24.1 Dressler's syndrome	0.237	0.762	0.000
M11.9 Crystal arthropathy, unspecified	0.236	0.763	0.001
M11.8 Other specified crystal arthropathies	0.235	0.764	0.001
M12.39 Palindromic rheumatism (Site unspecified)	0.235	0.764	0.000
L40-L45 Papulosquamous disorders	0.000	0.766	0.234
M11.26 Other chondrocalcinosis (Lower leg)	0.232	0.767	0.000
D73 Diseases of spleen	0.000	0.769	0.231
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.769	0.230
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.769	0.230
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.769	0.230
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.769	0.230
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.769	0.230
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.772	0.228
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.774	0.226
M14.4 Arthropathy in amyloidosis	0.224	0.775	0.001
M14.3 Lipoid dermatoarthritis	0.224	0.775	0.001
M14.1 Crystal arthropathy in other metabolic disorders	0.224	0.775	0.001
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.224	0.775	0.001
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.775	0.224
M14.8 Arthropathies in other specified diseases classified elsewhere	0.222	0.777	0.001
M12.38 Palindromic rheumatism (Other)	0.217	0.782	0.001
M12.37 Palindromic rheumatism (Ankle and foot)	0.217	0.782	0.001
M12.36 Palindromic rheumatism (Lower leg)	0.217	0.782	0.001
M12.35 Palindromic rheumatism (Pelvic region and thigh)	0.217	0.782	0.001
M12.34 Palindromic rheumatism (Hand)	0.217	0.782	0.001
M12.33 Palindromic rheumatism (Forearm)	0.217	0.782	0.001
M12.32 Palindromic rheumatism (Upper arm)	0.217	0.782	0.001
M12.31 Palindromic rheumatism (Shoulder region)	0.217	0.782	0.001
M10 Gout	0.216	0.783	0.001
M14.2 Diabetic arthropathy	0.215	0.784	0.001
D75 Other diseases of blood and blood-forming organs	0.000	0.785	0.215
D74 Methaemoglobinaemia	0.000	0.787	0.213
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.787	0.213
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.787	0.213
D53.9 Nutritional anaemia, unspecified	0.000	0.787	0.213
D76.3 Other histiocytosis syndromes	0.000	0.787	0.213
M12.24 Villonodular synovitis (pigmented) (Hand)	0.211	0.788	0.001
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.212	0.788	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.792	0.208
D72.8 Other specified disorders of white blood cells	0.000	0.792	0.208
M11.29 Other chondrocalcinosis (Site unspecified)	0.200	0.799	0.001
M11.28 Other chondrocalcinosis (Other)	0.200	0.799	0.001
M11.27 Other chondrocalcinosis (Ankle and foot)	0.200	0.799	0.001
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.200	0.799	0.001
M11.24 Other chondrocalcinosis (Hand)	0.200	0.799	0.001
M11.23 Other chondrocalcinosis (Forearm)	0.200	0.799	0.001
M11.22 Other chondrocalcinosis (Upper arm)	0.200	0.799	0.001
M11.21 Other chondrocalcinosis (Shoulder region)	0.200	0.799	0.001
M11.20 Other chondrocalcinosis (Multiple sites)	0.200	0.799	0.001
D72.1 Eosinophilia	0.000	0.801	0.199
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.801	0.199
M12.57 Traumatic arthropathy (Ankle and foot)	0.198	0.801	0.001
M12.88 Other specific arthropathies, not elsewhere classified (Other)	0.198	0.802	0.001
M13 Other arthritis	0.198	0.802	0.000
M12.59 Traumatic arthropathy (Site unspecified)	0.194	0.806	0.001
M12.58 Traumatic arthropathy (Other)	0.194	0.806	0.001
M12.56 Traumatic arthropathy (Lower leg)	0.194	0.806	0.001
M12.55 Traumatic arthropathy (Pelvic region and thigh)	0.194	0.806	0.001
M12.54 Traumatic arthropathy (Hand)	0.194	0.806	0.001
M12.53 Traumatic arthropathy (Forearm)	0.194	0.806	0.001
M12.52 Traumatic arthropathy (Upper arm)	0.194	0.806	0.001
M12.51 Traumatic arthropathy (Shoulder region)	0.194	0.806	0.001
M12.50 Traumatic arthropathy (Multiple sites)	0.194	0.806	0.001
M08.09 Juvenile rheumatoid arthritis (Site unspecified)	0.194	0.806	0.001
M12.89 Other specific arthropathies, not elsewhere classified (Site unspecified)	0.194	0.806	0.001
M12.87 Other specific arthropathies, not elsewhere classified (Ankle and foot)	0.194	0.806	0.001
M12.86 Other specific arthropathies, not elsewhere classified (Lower leg)	0.194	0.806	0.001
M12.85 Other specific arthropathies, not elsewhere classified (Pelvic region and thigh)	0.194	0.806	0.001
M12.84 Other specific arthropathies, not elsewhere classified (Hand)	0.194	0.806	0.001
M12.83 Other specific arthropathies, not elsewhere classified (Forearm)	0.194	0.806	0.001
M12.82 Other specific arthropathies, not elsewhere classified (Upper arm)	0.194	0.806	0.001
M12.81 Other specific arthropathies, not elsewhere classified (Shoulder region)	0.194	0.806	0.001
M12.80 Other specific arthropathies, not elsewhere classified (Multiple sites)	0.194	0.806	0.001
D81.9 Combined immunodeficiency, unspecified	0.000	0.806	0.194
D81.8 Other combined immunodeficiencies	0.000	0.806	0.194
D81.7 Major histocompatibility complex class II deficiency	0.000	0.806	0.194
D81.6 Major histocompatibility complex class I deficiency	0.000	0.806	0.194
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.806	0.194
D81.4 Nezelof's syndrome	0.000	0.806	0.194
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.806	0.194
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.806	0.194
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.806	0.194
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.806	0.194
D83.8 Other common variable immunodeficiencies	0.000	0.808	0.191
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.808	0.191
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.808	0.191
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.808	0.191
M12.09 Chronic postrheumatic arthropathy [Jaccoud] (Site unspecified)	0.191	0.809	0.001
M12.08 Chronic postrheumatic arthropathy [Jaccoud] (Other)	0.191	0.809	0.001
M12.07 Chronic postrheumatic arthropathy [Jaccoud] (Ankle and foot)	0.191	0.809	0.001
M12.06 Chronic postrheumatic arthropathy [Jaccoud] (Lower leg)	0.191	0.809	0.001
M12.05 Chronic postrheumatic arthropathy [Jaccoud] (Pelvic region and thigh)	0.191	0.809	0.001
M12.04 Chronic postrheumatic arthropathy [Jaccoud] (Hand)	0.191	0.809	0.001
M12.03 Chronic postrheumatic arthropathy [Jaccoud] (Forearm)	0.191	0.809	0.001
M12.02 Chronic postrheumatic arthropathy [Jaccoud] (Upper arm)	0.191	0.809	0.001
M12.01 Chronic postrheumatic arthropathy [Jaccoud] (Shoulder region)	0.191	0.809	0.001
M12.00 Chronic postrheumatic arthropathy [Jaccoud] (Multiple sites)	0.191	0.809	0.001
M12.19 Kaschin-Beck disease (Site unspecified)	0.191	0.809	0.001
M12.18 Kaschin-Beck disease (Other)	0.191	0.809	0.001
M12.17 Kaschin-Beck disease (Ankle and foot)	0.191	0.809	0.001
M12.16 Kaschin-Beck disease (Lower leg)	0.191	0.809	0.001
M12.15 Kaschin-Beck disease (Pelvic region and thigh)	0.191	0.809	0.001
M12.14 Kaschin-Beck disease (Hand)	0.191	0.809	0.001
M12.13 Kaschin-Beck disease (Forearm)	0.191	0.809	0.001
M12.12 Kaschin-Beck disease (Upper arm)	0.191	0.809	0.001
M12.11 Kaschin-Beck disease (Shoulder region)	0.191	0.809	0.001
M12.10 Kaschin-Beck disease (Multiple sites)	0.191	0.809	0.001
M12.49 Intermittent hydrarthrosis (Site unspecified)	0.191	0.809	0.001
M12.48 Intermittent hydrarthrosis (Other)	0.191	0.809	0.001
M12.47 Intermittent hydrarthrosis (Ankle and foot)	0.191	0.809	0.001
M12.46 Intermittent hydrarthrosis (Lower leg)	0.191	0.809	0.001
M12.45 Intermittent hydrarthrosis (Pelvic region and thigh)	0.191	0.809	0.001
M12.44 Intermittent hydrarthrosis (Hand)	0.191	0.809	0.001
M12.43 Intermittent hydrarthrosis (Forearm)	0.191	0.809	0.001
M12.42 Intermittent hydrarthrosis (Upper arm)	0.191	0.809	0.001
M12.41 Intermittent hydrarthrosis (Shoulder region)	0.191	0.809	0.001
M12.40 Intermittent hydrarthrosis (Multiple sites)	0.191	0.809	0.001
D51.2 Transcobalamin II deficiency	0.000	0.809	0.191
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.809	0.191
M08.00 Juvenile rheumatoid arthritis (Multiple sites)	0.189	0.810	0.001
D84.1 Defects in the complement system	0.000	0.811	0.189
M12.29 Villonodular synovitis (pigmented) (Site unspecified)	0.188	0.811	0.001
M12.28 Villonodular synovitis (pigmented) (Other)	0.188	0.811	0.001
M12.27 Villonodular synovitis (pigmented) (Ankle and foot)	0.188	0.811	0.001
M12.25 Villonodular synovitis (pigmented) (Pelvic region and thigh)	0.188	0.811	0.001
M12.23 Villonodular synovitis (pigmented) (Forearm)	0.188	0.811	0.001
M12.22 Villonodular synovitis (pigmented) (Upper arm)	0.188	0.811	0.001
M12.21 Villonodular synovitis (pigmented) (Shoulder region)	0.188	0.811	0.001
M12.20 Villonodular synovitis (pigmented) (Multiple sites)	0.188	0.811	0.001
D83.9 Common variable immunodeficiency, unspecified	0.000	0.812	0.188
M08.08 Juvenile rheumatoid arthritis (Other)	0.185	0.814	0.001
M08.07 Juvenile rheumatoid arthritis (Ankle and foot)	0.185	0.814	0.001
M08.06 Juvenile rheumatoid arthritis (Lower leg)	0.185	0.814	0.001
M08.05 Juvenile rheumatoid arthritis (Pelvic region and thigh)	0.185	0.814	0.001
M08.04 Juvenile rheumatoid arthritis (Hand)	0.185	0.814	0.001
M08.03 Juvenile rheumatoid arthritis (Forearm)	0.185	0.814	0.001
M08.02 Juvenile rheumatoid arthritis (Upper arm)	0.185	0.814	0.001
M08.01 Juvenile rheumatoid arthritis (Shoulder region)	0.185	0.814	0.001
M06.48 Inflammatory polyarthropathy (Other)	0.184	0.815	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.184	0.815	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.184	0.815	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.184	0.815	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.184	0.815	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.184	0.815	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.184	0.815	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.182	0.818	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.819	0.181
D72.9 Disorder of white blood cells, unspecified	0.000	0.819	0.181
D72.0 Genetic anomalies of leukocytes	0.000	0.819	0.181
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.180	0.819	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.179	0.821	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.179	0.821	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.179	0.821	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.179	0.821	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.179	0.821	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.179	0.821	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.821	0.179
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.822	0.178
M11.09 Hydroxyapatite deposition disease (Site unspecified)	0.178	0.822	0.001
M11.08 Hydroxyapatite deposition disease (Other)	0.178	0.822	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations