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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs45570136
log Bayes Factor = 13.3696
Chromosome 11   position 113,806,744  (GRCh37) Explore rs45570136 on Ensembl!
Variant rs45570136 is part of Cluster X0032

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M47 Spondylosis
1.000 0.000 0.000
M45-M49 Spondylopathies
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M47.82 Other spondylosis (Cervical region)
1.000 0.000 0.000
M47.8 Other spondylosis
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
0.997 0.003 0.000
K90-K93 Other diseases of the digestive system
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.995 0.005 0.000
M50-M54 Other dorsopathies
0.993 0.007 0.000
K50-K52 Noninfective enteritis and colitis
0.993 0.007 0.000
K92 Other diseases of digestive system
0.992 0.008 0.000
Chapter V Mental and behavioural disorders
0.992 0.008 0.000
K52 Other non-infective gastro-enteritis and colitis
0.992 0.008 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.992 0.008 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.991 0.009 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.990 0.010 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.990 0.010 0.000
I30-I52 Other forms of heart disease
0.989 0.011 0.000
F10.1 Harmful use
0.988 0.012 0.000
Chapter IX Diseases of the circulatory system
0.988 0.012 0.000
M47.9 Spondylosis, unspecified
0.984 0.016 0.000
K92.0 Haematemesis
0.979 0.021 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.967 0.033 0.000
M47.86 Other spondylosis (Lumbar region)
0.966 0.034 0.000
M51 Other intervertebral disk disorders
0.962 0.038 0.000
I47 Paroxysmal tachycardia
0.961 0.039 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.956 0.044 0.000
M48 Other spondylopathies
0.946 0.054 0.000
I49 Other cardiac arrhythmias
0.942 0.058 0.000
I47.2 Ventricular tachycardia
0.938 0.062 0.000
I45 Other conduction disorders
0.934 0.066 0.000
S90-S99 Injuries to the ankle and foot
0.930 0.070 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.926 0.074 0.000
M50 Cervical disk disorders
0.922 0.078 0.000
Chapter VIII Diseases of the ear and mastoid process
0.920 0.080 0.000
Y43 Primarily systemic agents
0.919 0.081 0.000
S80-S89 Injuries to the knee and lower leg
0.908 0.092 0.000
M48.0 Spinal stenosis
0.907 0.093 0.000
M51.2 Other specified intervertebral disk displacement
0.907 0.093 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.906 0.094 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.906 0.094 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.903 0.097 0.000
I45.1 Other and unspecified right bundle-branch block
0.902 0.098 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.902 0.098 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.901 0.099 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.898 0.102 0.000
I34 Nonrheumatic mitral valve disorders
0.889 0.111 0.000
M46 Other inflammatory spondylopathies
0.886 0.114 0.000
Q60-Q64 Congenital malformations of the urinary system
0.884 0.116 0.000
Y43.3 Other antineoplastic drugs
0.884 0.116 0.000
H90-H95 Other disorders of ear
0.883 0.117 0.000
M48.06 Spinal stenosis (Lumbar region)
0.880 0.120 0.000
M80-M85 Disorders of bone density and structure
0.876 0.124 0.000
I49.5 Sick sinus syndrome
0.874 0.126 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.869 0.131 0.000
K92.9 Disease of digestive system, unspecified
0.867 0.133 0.000
Chapter XXII Codes for special purposes
0.863 0.137 0.000
F30-F39 Mood [affective] disorders
0.856 0.144 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.855 0.145 0.000
I46 Cardiac arrest
0.855 0.145 0.000
I34.1 Mitral (valve) prolapse
0.852 0.148 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.851 0.149 0.000
I51 Complications and ill-defined descriptions of heart disease
0.849 0.151 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.848 0.152 0.000
K92.8 Other specified diseases of digestive system
0.847 0.153 0.000
K90 Intestinal malabsorption
0.844 0.156 0.000
M54 Dorsalgia
0.842 0.158 0.000
M40-M43 Deforming dorsopathies
0.839 0.161 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.838 0.162 0.000
S80 Superficial injury of lower leg
0.838 0.162 0.000
K91.4 Colostomy and enterostomy malfunction
0.837 0.163 0.000
M20-M25 Other joint disorders
0.837 0.163 0.000
K52.1 Toxic gastro-enteritis and colitis
0.836 0.164 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.836 0.164 0.000
W20-W49 Exposure to inanimate mechanical forces
0.833 0.167 0.000
Y83.8 Other surgical procedures
0.829 0.171 0.000
K92.1 Melaena
0.824 0.176 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.822 0.178 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.820 0.180 0.000
I51.8 Other ill-defined heart diseases
0.818 0.182 0.000
I05-I09 Chronic rheumatic heart diseases
0.818 0.182 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.817 0.183 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.816 0.184 0.000
M54.2 Cervicalgia
0.815 0.185 0.000
D68 Other coagulation defects
0.810 0.190 0.000
F10.2 Dependence syndrome
0.810 0.190 0.000
M50.2 Other cervical disk displacement
0.805 0.195 0.000
I50 Heart failure
0.805 0.195 0.000
Q61 Cystic kidney disease
0.804 0.196 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.804 0.196 0.000
Y83.9 Surgical procedure, unspecified
0.803 0.197 0.000
M91-M94 Chondropathies
0.799 0.201 0.000
F10.0 Acute intoxication
0.797 0.203 0.000
Q80-Q89 Other congenital malformations
0.795 0.205 0.000
M86-M90 Other osteopathies
0.795 0.205 0.000
I49.8 Other specified cardiac arrhythmias
0.794 0.206 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.791 0.209 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.789 0.211 0.000
S80.9 Superficial injury of lower leg, unspecified
0.788 0.212 0.000
F10.9 Unspecified mental and behavioural disorder
0.787 0.213 0.000
M50.3 Other cervical disk degeneration
0.786 0.214 0.000
I46.0 Cardiac arrest with successful resuscitation
0.784 0.216 0.000
D70 Agranulocytosis
0.784 0.216 0.000
S40-S49 Injuries to the shoulder and upper arm
0.783 0.217 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.780 0.220 0.000
M54.22 Cervicalgia (Cervical region)
0.777 0.223 0.000
M21 Other acquired deformities of limbs
0.775 0.225 0.000
H91 Other hearing loss
0.774 0.226 0.000
X20-X29 Contact with venomous animals and plants
0.772 0.228 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.770 0.230 0.000
M47.2 Other spondylosis with radiculopathy
0.769 0.231 0.000
S92 Fracture of foot, except ankle
0.768 0.232 0.000
Y83.4 Other reconstructive surgery
0.768 0.232 0.000
T39.1 4-Aminophenol derivatives
0.767 0.233 0.000
W50-W64 Exposure to animate mechanical forces
0.767 0.233 0.000
Y83.5 Amputation of limb(s)
0.763 0.237 0.000
V10-V19 Pedal cyclist injured in transport accident
0.763 0.237 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.758 0.242 0.000
T66-T78 Other and unspecified effects of external causes
0.757 0.243 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.757 0.243 0.000
F11 Mental and behavioural disorders due to use of opioids
0.756 0.244 0.000
K25 Gastric ulcer
0.754 0.246 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.754 0.246 0.000
Y40 Systemic antibiotics
0.753 0.247 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.752 0.248 0.000
T79-T79 Certain early complications of trauma
0.749 0.251 0.000
Q50-Q56 Congenital malformations of genital organs
0.749 0.251 0.000
I31 Other diseases of pericardium
0.748 0.252 0.000
M84 Disorders of continuity of bone
0.747 0.253 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.746 0.254 0.000
S91 Open wound of ankle and foot
0.745 0.255 0.000
M60-M63 Disorders of muscles
0.744 0.256 0.000
V40-V49 Car occupant injured in transport accident
0.744 0.256 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.744 0.256 0.000
M50.0 Cervical disk disorder with myelopathy
0.744 0.256 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.742 0.258 0.000
Y52 Agents primarily affecting the cardiovascular system
0.741 0.259 0.000
S60-S69 Injuries to the wrist and hand
0.740 0.260 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.740 0.260 0.000
I50.9 Heart failure, unspecified
0.740 0.260 0.000
X60-X84 Intentional self-harm
0.738 0.262 0.000
M65-M68 Disorders of synovium and tendon
0.738 0.262 0.000
I47.0 Reentry ventricular arrhythmia
0.736 0.264 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.736 0.264 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.735 0.265 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.735 0.265 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.734 0.266 0.000
K90.9 Intestinal malabsorption, unspecified
0.732 0.268 0.000
S81 Open wound of lower leg
0.731 0.269 0.000
W22 Striking against or struck by other objects
0.731 0.269 0.000
H93 Other disorders of ear, not elsewhere classified
0.730 0.270 0.000
M48.02 Spinal stenosis (Cervical region)
0.728 0.272 0.000
M00-M03 Infectious arthropathies
0.728 0.272 0.000
V20-V29 Motorcycle rider injured in transport accident
0.727 0.273 0.000
M43 Other deforming dorsopathies
0.726 0.274 0.000
M51.8 Other specified intervertebral disk disorders
0.723 0.277 0.000
I49.0 Ventricular fibrillation and flutter
0.722 0.278 0.000
I45.5 Other specified heart block
0.722 0.278 0.000
M70-M79 Other soft tissue disorders
0.721 0.279 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.720 0.280 0.000
S99 Other and unspecified injuries of ankle and foot
0.718 0.282 0.000
M47.1 Other spondylosis with myelopathy
0.718 0.282 0.000
D73 Diseases of spleen
0.717 0.283 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.717 0.283 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.717 0.283 0.000
M47.84 Other spondylosis (Thoracic region)
0.717 0.283 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.717 0.283 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.717 0.283 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.717 0.283 0.000
M49 Spondylopathies in diseases classified elsewhere
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
H90 Conductive and sensorineural hearing loss
0.717 0.283 0.000
K91.0 Vomiting following gastro-intestinal surgery
0.715 0.284 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.715 0.285 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.714 0.285 0.000
Y44 Agents primarily affecting blood constituents
0.714 0.285 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.713 0.287 0.000
Y35-Y36 Legal intervention and operations of war
0.713 0.287 0.000
Y10-Y34 Event of undetermined intent
0.713 0.287 0.000
Y00-Y09 Assault
0.713 0.287 0.000
X85-X99 Assault
0.713 0.287 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.713 0.287 0.000
X50-X57 Overexertion, travel and privation
0.713 0.287 0.000
X30-X39 Exposure to forces of nature
0.713 0.287 0.000
X10-X19 Contact with heat and hot substances
0.713 0.287 0.000
X00-X09 Exposure to smoke, fire and flames
0.713 0.287 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.713 0.287 0.000
W75-W84 Other accidental threats to breathing
0.713 0.287 0.000
W65-W74 Accidental drowning and submersion
0.713 0.287 0.000
V98-V99 Other and unspecified transport accidents
0.713 0.287 0.000
V95-V97 Air and space transport accidents
0.713 0.287 0.000
V90-V94 Water transport accidents
0.713 0.287 0.000
V80-V89 Other land transport accidents
0.713 0.287 0.000
V70-V79 Bus occupant injured in transport accident
0.713 0.287 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.713 0.287 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.713 0.287 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.713 0.287 0.000
V01-V09 Pedestrian injured in transport accident
0.713 0.287 0.000
M81 Osteoporosis without pathological fracture
0.712 0.288 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.712 0.288 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.712 0.288 0.000
F70-F79 Mental retardation
0.712 0.288 0.000
K52.3 Indeterminate colitis
0.711 0.288 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.711 0.288 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.711 0.289 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.711 0.289 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.711 0.289 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.711 0.289 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.711 0.289 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.711 0.289 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.710 0.290 0.000
F10.8 Other mental and behavioural disorders
0.710 0.290 0.000
F10.7 Residual and late-onset psychotic disorder
0.710 0.290 0.000
F10.6 Amnesic syndrome
0.710 0.290 0.000
F10.5 Psychotic disorder
0.710 0.290 0.000
F10.4 Withdrawal state with delirium
0.710 0.290 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.710 0.290 0.000
T33-T35 Frostbite
0.710 0.290 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.710 0.290 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.710 0.290 0.000
T00-T07 Injuries involving multiple body regions
0.710 0.290 0.000
F60-F69 Disorders of adult personality and behaviour
0.709 0.291 0.000
I52 Other heart disorders in diseases classified elsewhere
0.709 0.291 0.000
I48 Atrial fibrillation and flutter
0.709 0.291 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.709 0.291 0.000
I41 Myocarditis in diseases classified elsewhere
0.709 0.291 0.000
I40 Acute myocarditis
0.709 0.291 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.709 0.291 0.000
I37 Pulmonary valve disorders
0.709 0.291 0.000
I32 Pericarditis in diseases classified elsewhere
0.709 0.291 0.000
I30 Acute pericarditis
0.709 0.291 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.709 0.291 0.000
I00-I02 Acute rheumatic fever
0.708 0.291 0.000
I36 Nonrheumatic tricuspid valve disorders
0.708 0.292 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.707 0.293 0.000
K35-K38 Diseases of appendix
0.706 0.294 0.000
I05 Rheumatic mitral valve diseases
0.706 0.294 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.705 0.294 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.705 0.294 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.705 0.294 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.705 0.294 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.705 0.294 0.000
I49.9 Cardiac arrhythmia, unspecified
0.704 0.296 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.704 0.296 0.000
F32 Depressive episode
0.701 0.299 0.000
S90 Superficial injury of ankle and foot
0.701 0.299 0.000
D68.8 Other specified coagulation defects
0.700 0.300 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.700 0.300 0.000
M85 Other disorders of bone density and structure
0.700 0.300 0.000
S10-S19 Injuries to the neck
0.699 0.301 0.000
Y83.0 Surgical operation with transplant of whole organ
0.698 0.302 0.000
Q63 Other congenital malformations of kidney
0.697 0.302 0.000
H80-H83 Diseases of inner ear
0.697 0.303 0.000
M54.29 Cervicalgia-Site unspe
0.697 0.303 0.000
H91.9 Hearing loss, unspecified
0.697 0.303 0.000
I33 Acute and subacute endocarditis
0.697 0.303 0.000
I49.3 Ventricular premature depolarisation
0.696 0.304 0.000
Y59 Other and unspecified vaccines and biological substances
0.693 0.307 0.000
Y58 Bacterial vaccines
0.693 0.307 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.693 0.307 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.693 0.307 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.693 0.307 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.693 0.307 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.693 0.307 0.000
Y48 Anaesthetics and therapeutic gases
0.693 0.307 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.693 0.307 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.693 0.307 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.693 0.307 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.693 0.307 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.691 0.309 0.000
M51.3 Other specified intervertebral disk degeneration
0.690 0.310 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.690 0.310 0.000
M51.4 Schmorl's nodes
0.690 0.310 0.000
T92 Sequelae of injuries of upper limb
0.688 0.312 0.000
M51.9 Intervertebral disk disorder, unspecified
0.686 0.314 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.685 0.315 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.685 0.315 0.000
Q35-Q37 Cleft lip and cleft palate
0.685 0.315 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.685 0.315 0.000
I38 Endocarditis, valve unspecified
0.685 0.315 0.000
M53 Other dorsopathies, not elsewhere classified
0.681 0.318 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.681 0.319 0.000
I60-I69 Cerebrovascular diseases
0.678 0.322 0.000
M48.9 Spondylopathy, unspecified
0.678 0.322 0.000
M48.8 Other specified spondylopathies
0.678 0.322 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.678 0.322 0.000
M48.4 Fatigue fracture of vertebra
0.678 0.322 0.000
M48.3 Traumatic spondylopathy
0.678 0.322 0.000
M48.2 Kissing spine
0.678 0.322 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.678 0.322 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.677 0.322 0.000
M45 Ankylosing spondylitis
0.677 0.323 0.000
M21.3 Wrist or foot drop (acquired)
0.677 0.323 0.000
F80-F89 Disorders of psychological development
0.676 0.324 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.676 0.324 0.000
I49.2 Junctional premature depolarisation
0.675 0.325 0.000
I49.1 Atrial premature depolarisation
0.675 0.325 0.000
S83.2 Tear of meniscus, current
0.675 0.325 0.000
D68.2 Hereditary deficiency of other clotting factors
0.675 0.325 0.000
D68.6 Other Thrombophilia
0.674 0.326 0.000
F31 Bipolar affective disorder
0.673 0.327 0.000
Q61.0 Congenital single renal cyst
0.671 0.329 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.670 0.330 0.000
I45.8 Other specified conduction disorders
0.670 0.330 0.000
I45.4 Nonspecific intraventricular block
0.670 0.330 0.000
I45.3 Trifascicular block
0.670 0.330 0.000
I45.2 Bifascicular block
0.670 0.330 0.000
I45.0 Right fascicular block
0.670 0.330 0.000
H95.1 Other disorders following mastoidectomy
0.669 0.331 0.000
S98 Traumatic amputation of ankle and foot
0.667 0.333 0.000
S97 Crushing injury of ankle and foot
0.667 0.333 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.667 0.333 0.000
S95 Injury of blood vessels at ankle and foot level
0.667 0.333 0.000
S94 Injury of nerves at ankle and foot level
0.667 0.333 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.666 0.333 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.666 0.334 0.000
Chapter I Certain infectious and parasitic diseases
0.666 0.334 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.665 0.335 0.000
T90 Sequelae of injuries of head
0.662 0.337 0.000
Y43.4 Immunosuppressive agents
0.662 0.338 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.662 0.338 0.000
M50.9 Cervical disk disorder, unspecified
0.661 0.339 0.000
M50.8 Other cervical disk disorders
0.661 0.339 0.000
S80.0 Contusion of knee
0.661 0.339 0.000
Q61.3 Polycystic kidney, unspecified
0.660 0.340 0.000
M24 Other specific joint derangements
0.660 0.340 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.659 0.341 0.000
Y43.9 Primarily systemic agent, unspecified
0.659 0.341 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.659 0.341 0.000
Y43.6 Enzymes, not elsewhere classified
0.659 0.341 0.000
Y43.5 Acidifying and alkalising agents
0.659 0.341 0.000
Y43.2 Antineoplastic natural products
0.659 0.341 0.000
Y43.1 Antineoplastic antimetabolites
0.659 0.341 0.000
Y43.0 Antiallergic and antiemetic drugs
0.659 0.341 0.000
W22.9 Unspecified place
0.658 0.342 0.000
F99-F99 Unspecified mental disorder
0.657 0.343 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.656 0.344 0.000
M25 Other joint disorders, not elsewhere classified
0.655 0.345 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.655 0.345 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.654 0.346 0.000
Q00-Q07 Congenital malformations of the nervous system
0.654 0.346 0.000
K70-K77 Diseases of liver
0.653 0.346 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.653 0.347 0.000
F10.3 Withdrawal state
0.653 0.347 0.000
S93.1 Dislocation of toe(s)
0.652 0.348 0.000
F33 Recurrent depressive disorder
0.652 0.348 0.000
Y57 Other and unspecified drugs and medicaments
0.651 0.349 0.000
S88 Traumatic amputation of lower leg
0.651 0.349 0.000
S87 Crushing injury of lower leg
0.651 0.349 0.000
S86 Injury of muscle and tendon at lower leg level
0.651 0.349 0.000
S85 Injury of blood vessels at lower leg level
0.651 0.349 0.000
S84 Injury of nerves at lower leg level
0.651 0.349 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.651 0.349 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.650 0.350 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.650 0.350 0.000
M48.04 Spinal stenosis (Thoracic region)
0.650 0.350 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.650 0.350 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.650 0.350 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.650 0.350 0.000
Q61.2 Polycystic kidney, adult type
0.650 0.350 0.000
D55-D59 Haemolytic anaemias
0.650 0.350 0.000
Q85 Phakomatoses, not elsewhere classified
0.649 0.351 0.000
D75 Other diseases of blood and blood-forming organs
0.649 0.351 0.000
T56 Toxic effect of metals
0.647 0.353 0.000
K22 Other diseases of oesophagus
0.647 0.353 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.646 0.354 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.646 0.354 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.646 0.354 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.646 0.354 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.646 0.354 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.646 0.354 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.646 0.354 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.646 0.354 0.000
T36 Poisoning by systemic antibiotics
0.646 0.354 0.000
K91.9 Postprocedural disorder of digestive system, unspecified
0.646 0.354 0.000
K91.5 Postcholecystectomy syndrome
0.646 0.354 0.000
K91.2 Postsurgical malabsorption, not elsewhere classified
0.646 0.354 0.000
K91.1 Postgastric surgery syndromes
0.646 0.354 0.000
Y46.4 Iminostilbenes
0.646 0.354 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.646 0.354 0.000
M54.4 Lumbago with sciatica
0.645 0.355 0.000
M21.1 Varus deformity, not elsewhere classified
0.645 0.355 0.000
I45.9 Conduction disorder, unspecified
0.644 0.356 0.000
S92.1 Fracture of talus
0.643 0.357 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.643 0.357 0.000
I07 Rheumatic tricuspid valve diseases
0.638 0.362 0.000
M92 Other juvenile osteochondrosis
0.637 0.362 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.637 0.363 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.637 0.363 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.637 0.363 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.636 0.364 0.000
Chapter VI Diseases of the nervous system
0.635 0.365 0.000
M46.8 Other specified inflammatory spondylopathies
0.635 0.365 0.000
M46.5 Other infective spondylopathies
0.635 0.365 0.000
M46.4 Discitis, unspecified
0.635 0.365 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.635 0.365 0.000
M46.2 Osteomyelitis of vertebra
0.635 0.365 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.635 0.365 0.000
M46.0 Spinal enthesopathy
0.635 0.365 0.000
M72 Fibroblastic disorders
0.634 0.366 0.000
Q64 Other congenital malformations of urinary system
0.634 0.366 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.634 0.366 0.000
M89 Other disorders of bone
0.634 0.366 0.000
S61 Open wound of wrist and hand
0.633 0.367 0.000
T91 Sequelae of injuries of neck and trunk
0.633 0.367 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.633 0.367 0.000
D68.5 Primary Thrombophilia
0.633 0.367 0.000
S93.0 Dislocation of ankle joint
0.631 0.368 0.000
I63 Cerebral infarction
0.631 0.369 0.000
T39.0 Salicylates
0.630 0.370 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.629 0.371 0.000
M83 Adult osteomalacia
0.628 0.372 0.000
M82 Osteoporosis in diseases classified elsewhere
0.628 0.372 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.628 0.372 0.000
K25.7 Chronic without haemorrhage or perforation
0.626 0.374 0.000
Y40.9 Systemic antibiotic, unspecified
0.626 0.374 0.000
S89 Other and unspecified injuries of lower leg
0.625 0.375 0.000
H81 Disorders of vestibular function
0.625 0.375 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.623 0.377 0.000
K22.7 Barrett's oesophagus
0.623 0.377 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.622 0.378 0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)
0.622 0.378 0.000
D73.0 Hyposplenism
0.621 0.379 0.000
H93.1 Tinnitus
0.620 0.380 0.000
D80-D89 Certain disorders involving the immune mechanism
0.619 0.381 0.000
Q89 Other congenital malformations, not elsewhere classified
0.617 0.383 0.000
S92.0 Fracture of calcaneus
0.616 0.384 0.000
T59 Toxic effect of other gases, fumes and vapours
0.615 0.385 0.000
H65-H75 Diseases of middle ear and mastoid
0.614 0.386 0.000
F38 Other mood [affective] disorders
0.613 0.386 0.000
F34 Persistent mood [affective] disorders
0.613 0.386 0.000
F30 Manic episode
0.613 0.386 0.000
F39 Unspecified mood [affective] disorder
0.613 0.386 0.000
M05-M14 Inflammatory polyarthropathies
0.613 0.387 0.000
W00-W19 Falls
0.613 0.387 0.000
I46.1 Sudden cardiac death, so described
0.613 0.387 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.613 0.387 0.000
M31 Other necrotising vasculopathies
0.613 0.387 0.000
T51 Toxic effect of alcohol
0.613 0.387 0.000
X23 Contact with hornets, wasps and bees
0.612 0.388 0.000
F12.1 Harmful use
0.611 0.389 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.611 0.389 0.000
M65 Synovitis and tenosynovitis
0.610 0.389 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.610 0.390 0.000
D74 Methaemoglobinaemia
0.610 0.390 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.610 0.390 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.610 0.390 0.000
I51.6 Cardiovascular disease, unspecified
0.609 0.391 0.000
I51.5 Myocardial degeneration
0.609 0.391 0.000
I51.4 Myocarditis, unspecified
0.609 0.391 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.609 0.391 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.609 0.391 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.609 0.391 0.000
I51.0 Cardiac septal defect, acquired
0.609 0.391 0.000
M81.9 Osteoporosis, unspecified
0.609 0.391 0.000
I47.1 Supraventricular tachycardia
0.609 0.391 0.000
W44 Foreign body entering into or through eye or natural orifice
0.608 0.392 0.000
D67 Hereditary factor IX deficiency
0.608 0.392 0.000
D66 Hereditary factor VIII deficiency
0.608 0.392 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.608 0.392 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.607 0.393 0.000
D68.0 Von Willebrand's disease
0.607 0.393 0.000
Chapter X Diseases of the respiratory system
0.605 0.395 0.000
K90.8 Other intestinal malabsorption
0.605 0.395 0.000
K90.3 Pancreatic steatorrhoea
0.605 0.395 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.605 0.395 0.000
K90.1 Tropical sprue
0.605 0.395 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.605 0.395 0.000
K25.3 Acute without haemorrhage or perforation
0.605 0.395 0.000
M50.1 Cervical disk disorder with radiculopathy
0.605 0.395 0.000
M43.0 Spondylolysis
0.604 0.396 0.000
M54.8 Other dorsalgia
0.604 0.396 0.000
M54.0 Panniculitis affecting regions of neck and back
0.604 0.396 0.000
W55 Bitten or struck by other mammals
0.603 0.397 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.603 0.397 0.000
M54.1 Radiculopathy
0.602 0.398 0.000
M42 Spinal osteochondrosis
0.601 0.398 0.000
M40 Kyphosis and lordosis
0.601 0.398 0.000
S80.7 Multiple superficial injuries of lower leg
0.601 0.399 0.000
Y83.3 Surgical operation with formation of external stoma
0.600 0.400 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.600 0.400 0.000
M34 Systemic sclerosis
0.600 0.400 0.000
M33 Dermatopolymyositis
0.600 0.400 0.000
M32 Systemic lupus erythematosus
0.600 0.400 0.000
M30 Polyarteritis nodosa and related conditions
0.600 0.400 0.000
T98 Sequelae of other and unspecified effects of external causes
0.599 0.401 0.000
T95 Sequelae of burns, corrosions and frostbite
0.599 0.401 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.599 0.401 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.599 0.401 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.599 0.401 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.599 0.401 0.000
I95 Hypotension
0.599 0.401 0.000
S91.1 Open wound of toe(s) without damage to nail
0.598 0.402 0.000
U89 Agent resistant to other and unspecified antibiotics
0.598 0.402 0.000
W46 Contact with hypodermic needle
0.597 0.403 0.000
W45 Foreign body or object entering through skin
0.597 0.403 0.000
W43 Exposure to vibration
0.597 0.403 0.000
W42 Exposure to noise
0.597 0.403 0.000
W41 Exposure to high-pressure jet
0.597 0.403 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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