TreeWAS – Variant ID: rs4557589

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S92 Fracture of foot, except ankle	0.131	0.869	0.000
S92.30 Fracture of metatarsal bone (closed)	0.130	0.870	0.000
S92.3 Fracture of metatarsal bone	0.130	0.870	0.000
S92.0 Fracture of calcaneus	0.125	0.875	0.000
S92.00 Fracture of calcaneus (closed)	0.122	0.878	0.000
S92.2 Fracture of other tarsal bone(s)	0.114	0.886	0.000
S92.5 Fracture of other toe	0.112	0.887	0.000
S92.9 Fracture of foot, unspecified	0.106	0.894	0.000
S92.1 Fracture of talus	0.106	0.894	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.102	0.898	0.000
S92.7 Multiple fractures of foot	0.100	0.900	0.000
S92.50 Fracture of other toe (closed)	0.093	0.907	0.000
S92.31 Fracture of metatarsal bone (open)	0.093	0.907	0.000
S92.4 Fracture of great toe	0.091	0.909	0.000
S92.51 Fracture of other toe (open)	0.091	0.909	0.000
S92.90 Fracture of foot, unspecified (closed)	0.088	0.912	0.000
S92.01 Fracture of calcaneus (open)	0.087	0.913	0.000
S92.11 Fracture of talus (open)	0.084	0.916	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.082	0.918	0.000
S92.10 Fracture of talus (closed)	0.081	0.919	0.000
S92.70 Multiple fractures of foot (closed)	0.077	0.923	0.000
S92.91 Fracture of foot, unspecified (open)	0.076	0.924	0.000
S92.71 Multiple fractures of foot (open)	0.072	0.928	0.000
S92.40 Fracture of great toe (closed)	0.067	0.932	0.000
S92.41 Fracture of great toe (open)	0.060	0.939	0.000
S90-S99 Injuries to the ankle and foot	0.054	0.946	0.000
S90 Superficial injury of ankle and foot	0.049	0.951	0.000
S90.0 Contusion of ankle	0.042	0.958	0.000
S90.1 Contusion of toe(s) without damage to nail	0.040	0.960	0.000
S97 Crushing injury of ankle and foot	0.040	0.960	0.000
S90.8 Other superficial injuries of ankle and foot	0.039	0.961	0.000
S95 Injury of blood vessels at ankle and foot level	0.039	0.961	0.000
S94 Injury of nerves at ankle and foot level	0.039	0.961	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.038	0.962	0.000
S98 Traumatic amputation of ankle and foot	0.037	0.963	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.036	0.964	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.036	0.964	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.035	0.965	0.000
S90.2 Contusion of toe(s) with damage to nail	0.035	0.965	0.000
S91 Open wound of ankle and foot	0.035	0.965	0.000
S97.1 Crushing injury of toe(s)	0.030	0.969	0.000
S97.0 Crushing injury of ankle	0.029	0.971	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.029	0.971	0.000
S99 Other and unspecified injuries of ankle and foot	0.028	0.972	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.028	0.972	0.000
S94.8 Injury of other nerves at ankle and foot level	0.028	0.972	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.028	0.972	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.028	0.972	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.028	0.972	0.000
S94.1 Injury of medial plantar nerve	0.028	0.972	0.000
S94.0 Injury of lateral plantar nerve	0.028	0.972	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.028	0.972	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.028	0.972	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.028	0.972	0.000
S95.2 Injury of dorsal vein of foot	0.028	0.972	0.000
S95.1 Injury of plantar artery of foot	0.028	0.972	0.000
S95.0 Injury of dorsal artery of foot	0.028	0.972	0.000
S91.3 Open wound of other parts of foot	0.028	0.972	0.000
S93.1 Dislocation of toe(s)	0.028	0.972	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.027	0.973	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.027	0.973	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.027	0.973	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.027	0.973	0.000
S98.3 Traumatic amputation of other parts of foot	0.027	0.973	0.000
S98.2 Traumatic amputation of two or more toes	0.027	0.973	0.000
S98.0 Traumatic amputation of foot at ankle level	0.027	0.973	0.000
S90.3 Contusion of other and unspecified parts of foot	0.026	0.974	0.000
S93.0 Dislocation of ankle joint	0.026	0.974	0.000
S93.4 Sprain and strain of ankle	0.026	0.974	0.000
S93.5 Sprain and strain of toe(s)	0.026	0.974	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.026	0.974	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.026	0.974	0.000
S98.1 Traumatic amputation of one toe	0.025	0.975	0.000
S91.7 Multiple open wounds of ankle and foot	0.025	0.975	0.000
S91.1 Open wound of toe(s) without damage to nail	0.024	0.976	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.024	0.976	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.023	0.976	0.000
C18.9 Colon, unspecified	0.000	0.976	0.024
S91.0 Open wound of ankle	0.023	0.977	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.022	0.978	0.000
S91.2 Open wound of toe(s) with damage to nail	0.022	0.978	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.021	0.979	0.000
C22.0 Liver cell carcinoma	0.000	0.979	0.021
S99.7 Multiple injuries of ankle and foot	0.020	0.979	0.000
S93.40 Sprain of unspecified ligament of ankle	0.019	0.981	0.000
C18 Malignant neoplasm of colon	0.000	0.981	0.019
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.000	0.982	0.018
S99.9 Unspecified injury of ankle and foot	0.018	0.982	0.000
C18.7 Sigmoid colon	0.000	0.983	0.017
C22.9 Liver, unspecified	0.000	0.983	0.017
C18.2 Ascending colon	0.000	0.983	0.017
C18.6 Descending colon	0.000	0.984	0.016
C15.3 Upper third of oesophagus	0.000	0.984	0.016
C15 Malignant neoplasm of oesophagus	0.000	0.984	0.016
C18.1 Appendix	0.000	0.984	0.015
C15.4 Middle third of oesophagus	0.000	0.985	0.015
S99.8 Other specified injuries of ankle and foot	0.014	0.985	0.000
C15-C26 Malignant neoplasms of digestive organs	0.000	0.986	0.014
C18.8 Overlapping lesion of colon	0.000	0.986	0.014
D75.1 Secondary polycythaemia	0.014	0.986	0.000
C22.7 Other specified carcinomas of liver	0.000	0.987	0.013
C22.4 Other sarcomas of liver	0.000	0.987	0.013
C22.3 Angiosarcoma of liver	0.000	0.987	0.013
C22.2 Hepatoblastoma	0.000	0.987	0.013
C15.0 Cervical part of oesophagus	0.000	0.987	0.013
C15.9 Oesophagus, unspecified	0.000	0.988	0.012
C18.5 Splenic flexure	0.000	0.988	0.012
C15.8 Overlapping lesion of oesophagus	0.000	0.988	0.011
C15.2 Abdominal part of oesophagus	0.000	0.988	0.011
J33.8 Other polyp of sinus	0.012	0.988	0.000
C17 Malignant neoplasm of small intestine	0.000	0.989	0.011
C17.9 Small intestine, unspecified	0.000	0.989	0.011
K62.6 Ulcer of anus and rectum	0.000	0.990	0.010
C15.1 Thoracic part of oesophagus	0.000	0.990	0.010
D75 Other diseases of blood and blood-forming organs	0.010	0.990	0.000
C21 Malignant neoplasm of anus and anal canal	0.000	0.990	0.010
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.000	0.990	0.010
C18.3 Hepatic flexure	0.000	0.990	0.009
D75.8 Other specified diseases of blood and blood-forming organs	0.009	0.991	0.000
K26.3 Acute without haemorrhage or perforation	0.009	0.991	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.000	0.991	0.009
N88.8 Other specified noninflammatory disorders of cervix uteri	0.009	0.991	0.000
G12.2 Motor neuron disease	0.000	0.991	0.008
C17.8 Overlapping lesion of small intestine	0.000	0.992	0.008
C17.3 Meckel's diverticulum	0.000	0.992	0.008
C26 Malignant neoplasm of other and ill-defined digestive organs	0.000	0.992	0.008
C45.0 Mesothelioma of pleura	0.008	0.992	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.008	0.992	0.000
D75.0 Familial erythrocytosis	0.008	0.992	0.000
D75.2 Essential thrombocytosis	0.008	0.992	0.000
C17.2 Ileum	0.000	0.992	0.007
C32.9 Larynx, unspecified	0.008	0.992	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.000	0.992	0.007
C17.1 Jejunum	0.000	0.993	0.007
C23 Malignant neoplasm of gallbladder	0.000	0.993	0.007
C22.1 Intrahepatic bile duct carcinoma	0.000	0.993	0.007
C21.2 Cloacogenic zone	0.000	0.993	0.007
C24.8 Overlapping lesion of biliary tract	0.000	0.993	0.007
C20 Malignant neoplasm of rectum	0.000	0.993	0.007
C24.9 Biliary tract, unspecified	0.000	0.993	0.007
C32 Malignant neoplasm of larynx	0.007	0.993	0.000
C24.1 Ampulla of Vater	0.000	0.993	0.007
S69.9 Unspecified injury of wrist and hand	0.007	0.993	0.000
C21.1 Anal canal	0.000	0.993	0.007
C24.0 Extrahepatic bile duct	0.000	0.993	0.007
C32.1 Supraglottis	0.007	0.993	0.000
C16 Malignant neoplasm of stomach	0.000	0.993	0.007
C21.0 Anus, unspecified	0.000	0.993	0.007
C32.0 Glottis	0.007	0.993	0.000
C15.5 Lower third of oesophagus	0.000	0.994	0.006
C26.8 Overlapping lesion of digestive system	0.000	0.994	0.006
C26.1 Spleen	0.000	0.994	0.006
C45 Mesothelioma	0.006	0.994	0.000
C18.0 Caecum	0.000	0.994	0.006
C45.9 Mesothelioma, unspecified	0.006	0.994	0.000
E27.1 Primary adrenocortical insufficiency	0.006	0.994	0.000
C16.8 Overlapping lesion of stomach	0.000	0.995	0.005
C32.8 Overlapping lesion of larynx	0.005	0.995	0.000
C17.0 Duodenum	0.000	0.995	0.005
C16.5 Lesser curvature of stomach, unspecified	0.000	0.995	0.005
C32.3 Laryngeal cartilage	0.005	0.995	0.000
C16.2 Body of stomach	0.000	0.995	0.005
C26.0 Intestinal tract, part unspecified	0.000	0.995	0.005
K63.1 Perforation of intestine (nontraumatic)	0.000	0.995	0.005
C16.4 Pylorus	0.000	0.995	0.005
A87.9 Viral meningitis, unspecified	0.000	0.995	0.005
C32.2 Subglottis	0.005	0.995	0.000
R09.1 Pleurisy	0.000	0.995	0.005
C45.7 Mesothelioma of other sites	0.005	0.995	0.000
G12 Spinal muscular atrophy and related syndromes	0.000	0.995	0.005
Z93.3 Colostomy status	0.000	0.995	0.005
H52.3 Anisometropia and aniseikonia	0.000	0.995	0.005
C16.6 Greater curvature of stomach, unspecified	0.000	0.995	0.005
C16.1 Fundus of stomach	0.000	0.995	0.005
C26.9 Ill-defined sites within the digestive system	0.000	0.995	0.004
C30.0 Nasal cavity	0.005	0.995	0.000
R09.0 Asphyxia	0.000	0.995	0.005
C45.2 Mesothelioma of pericardium	0.005	0.995	0.000
C45.1 Mesothelioma of peritoneum	0.005	0.995	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.004	0.996	0.000
C25 Malignant neoplasm of pancreas	0.000	0.996	0.004
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.004	0.996	0.000
C37 Malignant neoplasm of thymus	0.004	0.996	0.000
C16.3 Pyloric antrum	0.000	0.996	0.004
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.000	0.996	0.004
C25.7 Other parts of pancreas	0.000	0.996	0.004
C18.4 Transverse colon	0.000	0.996	0.003
G12.9 Spinal muscular atrophy, unspecified	0.000	0.996	0.004
G12.8 Other spinal muscular atrophies and related syndromes	0.000	0.996	0.004
G12.1 Other inherited spinal muscular atrophy	0.000	0.996	0.004
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]	0.000	0.996	0.004
C16.0 Cardia	0.000	0.996	0.004
C80.9 Malignant neoplasm, unspecified	0.004	0.996	0.000
N88 Other noninflammatory disorders of cervix uteri	0.004	0.996	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.004	0.996	0.000
I33.0 Acute and subacute infective endocarditis	0.000	0.996	0.004
E27 Other disorders of adrenal gland	0.004	0.996	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.000	0.996	0.004
C30.1 Middle ear	0.003	0.997	0.000
N88.9 Noninflammatory disorder of cervix uteri, unspecified	0.003	0.997	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.997	0.003
E23.7 Disorder of pituitary gland, unspecified	0.003	0.997	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.003	0.997	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.003	0.997	0.000
N88.3 Incompetence of cervix uteri	0.003	0.997	0.000
C25.0 Head of pancreas	0.000	0.997	0.003
E27.8 Other specified disorders of adrenal gland	0.003	0.997	0.000
C31 Malignant neoplasm of accessory sinuses	0.003	0.997	0.000
T92.1 Sequelae of fracture of arm	0.003	0.997	0.000
E23 Hypofunction and other disorders of pituitary gland	0.003	0.997	0.000
C25.4 Endocrine pancreas	0.000	0.997	0.003
D40.1 Testis	0.003	0.997	0.000
E28.3 Primary ovarian failure	0.003	0.997	0.000
C33 Malignant neoplasm of trachea	0.003	0.997	0.000
C38.3 Mediastinum, part unspecified	0.003	0.997	0.000
O63.0 Prolonged first stage (of labour)	0.003	0.997	0.000
A87 Viral meningitis	0.000	0.997	0.003
C25.2 Tail of pancreas	0.000	0.997	0.003
D35.1 Parathyroid gland	0.000	0.997	0.003
E26.0 Primary hyperaldosteronism	0.003	0.997	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.000	0.997	0.003
C38.4 Pleura	0.003	0.997	0.000
W57.0 Home	0.003	0.997	0.000
E26 Hyperaldosteronism	0.003	0.997	0.000
N88.4 Hypertrophic elongation of cervix uteri	0.003	0.997	0.000
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.003	0.997	0.000
C38.2 Posterior mediastinum	0.003	0.997	0.000
C38.1 Anterior mediastinum	0.003	0.997	0.000
C38.0 Heart	0.003	0.997	0.000
C25.8 Overlapping lesion of pancreas	0.000	0.997	0.003
E27.5 Adrenomedullary hyperfunction	0.003	0.997	0.000
E27.0 Other adrenocortical overactivity	0.003	0.997	0.000
R09.2 Respiratory arrest	0.000	0.997	0.003
S69 Other and unspecified injuries of wrist and hand	0.003	0.997	0.000
E20-E35 Disorders of other endocrine glands	0.003	0.997	0.000
C16.9 Stomach, unspecified	0.000	0.997	0.003
E27.2 Addisonian crisis	0.003	0.997	0.000
C25.3 Pancreatic duct	0.000	0.997	0.002
G63.2 Diabetic polyneuropathy	0.000	0.997	0.003
J99.8 Respiratory disorders in other diseases classified elsewhere	0.003	0.997	0.000
E23.0 Hypopituitarism	0.003	0.997	0.000
K82.8 Other specified diseases of gallbladder	0.003	0.997	0.000
N88.0 Leukoplakia of cervix uteri	0.003	0.997	0.000
C39.9 Ill-defined sites within the respiratory system	0.002	0.997	0.000
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.002	0.997	0.000
C39.0 Upper respiratory tract, part unspecified	0.002	0.997	0.000
E28 Ovarian dysfunction	0.003	0.997	0.000
N88.1 Old laceration of cervix uteri	0.003	0.997	0.000
A87.2 Lymphocytic choriomeningitis	0.000	0.997	0.003
E23.6 Other disorders of pituitary gland	0.003	0.997	0.000
E23.2 Diabetes insipidus	0.003	0.997	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.000	0.997	0.003
C31.9 Accessory sinus, unspecified	0.002	0.997	0.000
C31.8 Overlapping lesion of accessory sinuses	0.002	0.997	0.000
C31.3 Sphenoidal sinus	0.002	0.997	0.000
C31.2 Frontal sinus	0.002	0.997	0.000
C31.1 Ethmoidal sinus	0.002	0.997	0.000
C25.9 Pancreas, unspecified	0.000	0.997	0.003
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.002	0.997	0.000
E23.1 Drug-induced hypopituitarism	0.002	0.997	0.000
H53.4 Visual field defects	0.003	0.997	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.002	0.997	0.000
A87.0 Enteroviral meningitis	0.000	0.997	0.002
S69.8 Other specified injuries of wrist and hand	0.002	0.997	0.000
A87.8 Other viral meningitis	0.000	0.997	0.002
A87.1 Adenoviral meningitis	0.000	0.997	0.002
C31.0 Maxillary sinus	0.002	0.997	0.000
E26.9 Hyperaldosteronism, unspecified	0.002	0.997	0.000
S81.8 Open wound of other parts of lower leg	0.002	0.997	0.000
C25.1 Body of pancreas	0.000	0.998	0.002
C67.2 Lateral wall of bladder	0.002	0.998	0.000
E34 Other endocrine disorders	0.002	0.998	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.002	0.998	0.000
E32 Diseases of thymus	0.002	0.998	0.000
E26.8 Other hyperaldosteronism	0.002	0.998	0.000
E26.1 Secondary hyperaldosteronism	0.002	0.998	0.000
W55.0 Home	0.002	0.998	0.000
L72.0 Epidermal cyst	0.000	0.998	0.002
E31 Polyglandular dysfunction	0.002	0.998	0.000
E20 Hypoparathyroidism	0.002	0.998	0.000
G24.9 Dystonia, unspecified	0.002	0.998	0.000
H93.1 Tinnitus	0.002	0.998	0.000
I69.3 Sequelae of cerebral infarction	0.000	0.998	0.002
E35 Disorders of endocrine glands in diseases classified elsewhere	0.002	0.998	0.000
E30 Disorders of puberty, not elsewhere classified	0.002	0.998	0.000
E34.3 Short stature, not elsewhere classified	0.002	0.998	0.000
I45.1 Other and unspecified right bundle-branch block	0.002	0.998	0.000
O14.1 Severe preeclampsia	0.002	0.998	0.000
E24.2 Drug-induced Cushing's syndrome	0.002	0.998	0.000
E29 Testicular dysfunction	0.002	0.998	0.000
E24 Cushing's syndrome	0.002	0.998	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.000	0.998	0.002
E34.9 Endocrine disorder, unspecified	0.002	0.998	0.000
S43.1 Dislocation of acromioclavicular joint	0.002	0.998	0.000
D22.3 Melanocytic naevi of other and unspecified parts of face	0.002	0.998	0.000
E28.9 Ovarian dysfunction, unspecified	0.002	0.998	0.000
E28.8 Other ovarian dysfunction	0.002	0.998	0.000
E28.1 Androgen excess	0.002	0.998	0.000
E28.0 Oestrogen excess	0.002	0.998	0.000
G10 Huntington's disease	0.000	0.998	0.002
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.000	0.998	0.002
S72.00 Fracture of neck of femur (closed)	0.000	0.998	0.002
R09.3 Abnormal sputum	0.000	0.998	0.002
X23.9 Unspecified place	0.000	0.998	0.002
X41.9 Unspecified place	0.002	0.998	0.000
O36.9 Maternal care for foetal problem, unspecified	0.002	0.998	0.000
R68.0 Hypothermia, not associated with low environmental temperature	0.002	0.998	0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.002	0.998	0.000
E32.9 Disease of thymus, unspecified	0.002	0.998	0.000
J86.9 Pyothorax without fistula	0.000	0.998	0.002
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.002	0.998	0.000
E34.8 Other specified endocrine disorders	0.002	0.998	0.000
D40.7 Other male genital organs	0.002	0.998	0.000
E29.9 Testicular dysfunction, unspecified	0.002	0.998	0.000
E34.5 Androgen resistance syndrome	0.002	0.998	0.000
E34.4 Constitutional tall stature	0.002	0.998	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.002	0.998	0.000
E34.1 Other hypersecretion of intestinal hormones	0.002	0.998	0.000
J03.9 Acute tonsillitis, unspecified	0.000	0.998	0.002
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.002	0.998	0.000
E25 Adrenogenital disorders	0.002	0.998	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.002	0.998	0.000
B44.1 Other pulmonary aspergillosis	0.002	0.998	0.000
E32.8 Other diseases of thymus	0.002	0.998	0.000
E32.1 Abscess of thymus	0.002	0.998	0.000
E32.0 Persistent hyperplasia of thymus	0.002	0.998	0.000
W55 Bitten or struck by other mammals	0.002	0.998	0.000
E31.0 Autoimmune polyglandular failure	0.002	0.998	0.000
G72.9 Myopathy, unspecified	0.000	0.998	0.002
M23.3 Other meniscus derangements	0.000	0.998	0.002
E20.9 Hypoparathyroidism, unspecified	0.002	0.998	0.000
E27.9 Disorder of adrenal gland, unspecified	0.002	0.998	0.000
S69.7 Multiple injuries of wrist and hand	0.002	0.998	0.000
E20.8 Other hypoparathyroidism	0.002	0.998	0.000
E20.1 Pseudohypoparathyroidism	0.002	0.998	0.000
E20.0 Idiopathic hypoparathyroidism	0.002	0.998	0.000
E31.9 Polyglandular dysfunction, unspecified	0.002	0.998	0.000
E31.8 Other polyglandular dysfunction	0.002	0.998	0.000
E31.1 Polyglandular hyperfunction	0.002	0.998	0.000
K29.0 Acute haemorrhagic gastritis	0.000	0.998	0.002
R40.2 Coma, unspecified	0.000	0.998	0.002
E30.9 Disorder of puberty, unspecified	0.002	0.998	0.000
E30.8 Other disorders of puberty	0.002	0.998	0.000
E30.1 Precocious puberty	0.002	0.998	0.000
E30.0 Delayed puberty	0.002	0.998	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.002	0.998	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.002	0.998	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.002	0.998	0.000
E29.8 Other testicular dysfunction	0.002	0.998	0.000
E29.0 Testicular hyperfunction	0.002	0.998	0.000
E24.8 Other Cushing's syndrome	0.002	0.998	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.002	0.998	0.000
E24.3 Ectopic ACTH syndrome	0.002	0.998	0.000
E24.1 Nelson's syndrome	0.002	0.998	0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere	0.000	0.998	0.002
G11 Hereditary ataxia	0.000	0.998	0.002
S02.70 Multiple fractures involving skull and facial bones (closed)	0.002	0.998	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.998	0.002
Y04.8 Other specified place	0.002	0.998	0.000
W55.8 Other specified place	0.002	0.998	0.000
W57.9 Unspecified place	0.002	0.998	0.000
W57.7 Farm	0.002	0.998	0.000
W57.6 Industrial and construction area	0.002	0.998	0.000
W57.5 Trade and service area	0.002	0.998	0.000
W57.4 Street and highway	0.002	0.998	0.000
W57.3 Sports and athletics area	0.002	0.998	0.000
W57.2 School, other institution and public administrative area	0.002	0.998	0.000
W57.1 Residential institution	0.002	0.998	0.000
I84.1 Internal haemorrhoids with other complications	0.000	0.998	0.002
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.998	0.002
S02.00 Fracture of vault of skull (closed)	0.002	0.998	0.000
D40.9 Male genital organ, unspecified	0.002	0.998	0.000
E25.9 Adrenogenital disorder, unspecified	0.001	0.998	0.000
E25.8 Other adrenogenital disorders	0.001	0.998	0.000
V49.9 Car occupant [any] injured in unspecified traffic accident	0.002	0.998	0.000
Z11.5 Special screening examination for other viral diseases	0.002	0.998	0.000
E22 Hyperfunction of pituitary gland	0.002	0.998	0.000
M23.37 Other meniscus derangements-Capsular lig	0.000	0.998	0.002
D46.2 Refractory anaemia with excess of blasts	0.002	0.998	0.000
W50.2 School, other institution and public administrative area	0.002	0.998	0.000
W55.9 Unspecified place	0.002	0.998	0.000
W55.5 Trade and service area	0.002	0.998	0.000
W55.6 Industrial and construction area	0.002	0.998	0.000
W55.4 Street and highway	0.002	0.998	0.000
W55.3 Sports and athletics area	0.002	0.998	0.000
W55.2 School, other institution and public administrative area	0.002	0.998	0.000
W55.1 Residential institution	0.002	0.998	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.002	0.998	0.000
W55.7 Farm	0.002	0.998	0.000
W50.8 Other specified place	0.002	0.998	0.000
I33 Acute and subacute endocarditis	0.000	0.998	0.002
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.998	0.002
G11.1 Early-onset cerebellar ataxia	0.000	0.998	0.002
W57.8 Other specified place	0.002	0.998	0.000
D46 Myelodysplastic syndromes	0.002	0.998	0.000
B94.8 Sequelae of other specified infectious and parasitic diseases	0.000	0.998	0.002
D46.5 Refractory anaemia with multi-lineage dysplasia	0.002	0.998	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.002	0.998	0.000
I69 Sequelae of cerebrovascular disease	0.000	0.998	0.002
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.002	0.998	0.000
E34.0 Carcinoid syndrome	0.001	0.998	0.000
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere	0.000	0.998	0.001
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema	0.000	0.998	0.001
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease	0.000	0.998	0.001
G14 Postpolio syndrome	0.000	0.998	0.001
E24.9 Cushing's syndrome, unspecified	0.001	0.998	0.000
E24.0 Pituitary-dependent Cushing's disease	0.001	0.998	0.000
E29.1 Testicular hypofunction	0.002	0.998	0.000
G11.8 Other hereditary ataxias	0.000	0.998	0.001
G11.4 Hereditary spastic paraplegia	0.000	0.998	0.001
G11.3 Cerebellar ataxia with defective DNA repair	0.000	0.998	0.001
G11.2 Late-onset cerebellar ataxia	0.000	0.998	0.001
G11.0 Congenital nonprogressive ataxia	0.000	0.998	0.001
G13.0 Paraneoplastic neuromyopathy and neuropathy	0.000	0.998	0.001
M84.26 Delayed union of fracture (Lower leg)	0.002	0.998	0.000
X23.0 Home	0.000	0.998	0.002
L65.9 Nonscarring hair loss, unspecified	0.000	0.998	0.002
X23 Contact with hornets, wasps and bees	0.000	0.998	0.002
W50-W64 Exposure to animate mechanical forces	0.002	0.998	0.000
W57.99 Bitten or stung by nonvenomous insect and other nonvenomous arthropods: Unspecified place: During unspecified activity	0.001	0.998	0.000
H35.8 Other specified retinal disorders	0.002	0.998	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.002	0.998	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.998	0.001
S02.80 Fractures of other skull and facial bones (closed)	0.002	0.998	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.002	0.998	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.998	0.002
D46.1 Refractory anaemia with sideroblasts	0.001	0.998	0.000
E22.8 Other hyperfunction of pituitary gland	0.001	0.998	0.000
G90.2 Horner's syndrome	0.000	0.998	0.002
O14.0 Moderate preeclampsia	0.001	0.998	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.002	0.998	0.000
W55.58 Bitten or struck by other mammals; Trade and service area;While engaged in other specified activities	0.001	0.998	0.000
W55.99 Bitten or struck by other mammals: Unspecified place: During unspecified activity	0.001	0.998	0.000
D46.7 Other myelodysplastic syndromes	0.001	0.998	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.001	0.998	0.001
I33.9 Acute endocarditis, unspecified	0.000	0.998	0.001
T83.0 Mechanical complication of urinary (indwelling) catheter	0.000	0.998	0.002
D46.4 Refractory anaemia, unspecified	0.001	0.998	0.000
C71.1 Frontal lobe	0.001	0.999	0.000
Q21.0 Ventricular septal defect	0.000	0.999	0.001
C34.2 Middle lobe, bronchus or lung	0.001	0.999	0.000
D32.9 Meninges, unspecified	0.001	0.999	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.001	0.999	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.001	0.999	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.001	0.999	0.000
W50.3 Sports and athletics area	0.001	0.999	0.000
W50.7 Farm	0.001	0.999	0.000
W50.6 Industrial and construction area	0.001	0.999	0.000
W50.5 Trade and service area	0.001	0.999	0.000
W50.1 Residential institution	0.001	0.999	0.000
D40.0 Prostate	0.001	0.999	0.000
E28.2 Polycystic ovarian syndrome	0.001	0.999	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.001	0.999	0.000
S43.4 Sprain and strain of shoulder joint	0.001	0.999	0.000
Z80.8 Family history of malignant neoplasm of other organs or systems	0.001	0.999	0.000
G11.9 Hereditary ataxia, unspecified	0.000	0.999	0.001
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.999	0.001
Z11.4 Special screening examination for human immunodeficiency virus [HIV]	0.001	0.999	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.999	0.001
S02.7 Multiple fractures involving skull and facial bones	0.001	0.999	0.000
W50.9 Unspecified place	0.001	0.999	0.000
X23.7 Farm	0.000	0.999	0.001
X23.6 Industrial and construction area	0.000	0.999	0.001
X23.5 Trade and service area	0.000	0.999	0.001
X23.4 Street and highway	0.000	0.999	0.001
X23.3 Sports and athletics area	0.000	0.999	0.001
X23.2 School, other institution and public administrative area	0.000	0.999	0.001
X23.1 Residential institution	0.000	0.999	0.001
W59 Bitten or crushed by other reptiles	0.001	0.999	0.000
W58 Bitten or struck by crocodile or alligator	0.001	0.999	0.000
W56 Contact with marine animal	0.001	0.999	0.000
W54 Bitten or struck by dog	0.001	0.999	0.000
W53 Bitten by rat	0.001	0.999	0.000
W52 Crushed, pushed and stepped on by crowd or human stampede	0.001	0.999	0.000
D35.2 Pituitary gland	0.000	0.999	0.001
K05.6 Periodontal disease, unspecified	0.001	0.999	0.000
X23.8 Other specified place	0.000	0.999	0.001
G72.8 Other specified myopathies	0.000	0.999	0.001
J04.1 Acute tracheitis	0.000	0.999	0.001
S43.6 Sprain and strain of sternoclavicular joint	0.001	0.999	0.000
S43.2 Dislocation of sternoclavicular joint	0.001	0.999	0.000
W50.0 Home	0.001	0.999	0.000
S02.0 Fracture of vault of skull	0.001	0.999	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.001	0.999	0.000
T75.4 Effects of electric current	0.001	0.999	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.001	0.999	0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.001	0.999	0.000
L94.0 Localised scleroderma [morphea]	0.001	0.999	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.001	0.999	0.000
S43.0 Dislocation of shoulder joint	0.001	0.999	0.000
G72 Other myopathies	0.000	0.999	0.001
W60 Contact with plant thorns and spines and sharp leaves	0.001	0.999	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.001	0.999	0.000
D32.0 Cerebral meninges	0.001	0.999	0.000
N88.2 Stricture and stenosis of cervix uteri	0.001	0.999	0.000
Z75.5 Holiday relief care	0.001	0.999	0.000
Z81.8 Family history of other mental and behavioural disorders	0.000	0.999	0.001
W50.30 Hit, struck, kicked, twisted, bitten or scratched by another person; Sports and athletics area;While engaged in sports activity	0.001	0.999	0.000
W50.4 Street and highway	0.001	0.999	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations