TreeWAS – Variant ID: rs4574025

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D86.9 Sarcoidosis, unspecified	0.000	0.898	0.102
D86 Sarcoidosis	0.000	0.931	0.069
K76.0 Fatty (change of) liver, not elsewhere classified	0.058	0.942	0.000
D86.0 Sarcoidosis of lung	0.000	0.943	0.057
D86.3 Sarcoidosis of skin	0.000	0.944	0.056
D86.1 Sarcoidosis of lymph nodes	0.000	0.950	0.050
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.954	0.046
D86.8 Sarcoidosis of other and combined sites	0.000	0.961	0.039
D80-D89 Certain disorders involving the immune mechanism	0.000	0.968	0.032
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.972	0.028
D80 Immunodeficiency with predominantly antibody defects	0.000	0.976	0.024
D89.1 Cryoglobulinaemia	0.000	0.976	0.024
D81 Combined immunodeficiencies	0.000	0.977	0.023
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.977	0.023
D82 Immunodeficiency associated with other major defects	0.000	0.979	0.021
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.979	0.021
D84 Other immunodeficiencies	0.000	0.979	0.020
D83 Common variable immunodeficiency	0.000	0.979	0.020
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.980	0.020
D89.3 Immune reconstitution syndrome	0.000	0.980	0.020
N31.8 Other neuromuscular dysfunction of bladder	0.019	0.981	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.981	0.019
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.981	0.019
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.982	0.018
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.983	0.017
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.983	0.017
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.983	0.017
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.983	0.017
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.983	0.017
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.983	0.017
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.983	0.017
D81.9 Combined immunodeficiency, unspecified	0.000	0.983	0.017
D81.8 Other combined immunodeficiencies	0.000	0.983	0.017
D81.7 Major histocompatibility complex class II deficiency	0.000	0.983	0.017
D81.6 Major histocompatibility complex class I deficiency	0.000	0.983	0.017
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.983	0.017
D81.4 Nezelof's syndrome	0.000	0.983	0.017
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.983	0.017
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.983	0.017
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.983	0.017
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.983	0.017
J39.8 Other specified diseases of upper respiratory tract	0.016	0.984	0.000
D84.8 Other specified immunodeficiencies	0.000	0.984	0.016
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.984	0.015
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.984	0.015
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.984	0.015
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.984	0.015
D82.2 Immunodeficiency with short-limbed stature	0.000	0.984	0.015
D82.0 Wiskott-Aldrich syndrome	0.000	0.984	0.015
D84.1 Defects in the complement system	0.000	0.985	0.015
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.985	0.015
D83.8 Other common variable immunodeficiencies	0.000	0.985	0.015
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.985	0.015
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.985	0.015
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.985	0.015
D82.1 Di George's syndrome	0.000	0.986	0.014
K76 Other diseases of liver	0.013	0.987	0.000
D83.9 Common variable immunodeficiency, unspecified	0.000	0.988	0.012
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.988	0.012
C22.0 Liver cell carcinoma	0.011	0.988	0.000
K76.7 Hepatorenal syndrome	0.011	0.989	0.000
C22.9 Liver, unspecified	0.011	0.989	0.000
D84.9 Immunodeficiency, unspecified	0.000	0.989	0.010
K76.1 Chronic passive congestion of liver	0.010	0.990	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.010	0.990	0.000
K65.0 Acute peritonitis	0.000	0.990	0.010
I47.1 Supraventricular tachycardia	0.010	0.990	0.000
C44.2 Skin of ear and external auricular canal	0.009	0.991	0.000
K76.5 Hepatic veno-occlusive disease	0.009	0.991	0.000
K76.4 Peliosis hepatis	0.009	0.991	0.000
K76.3 Infarction of liver	0.009	0.991	0.000
K76.2 Central haemorrhagic necrosis of liver	0.009	0.991	0.000
M19.96 Arthrosis, unspecified-Lower leg	0.000	0.991	0.009
J93.9 Pneumothorax, unspecified	0.000	0.992	0.008
B18.2 Chronic viral hepatitis C	0.008	0.992	0.000
C22.1 Intrahepatic bile duct carcinoma	0.008	0.992	0.000
C22.7 Other specified carcinomas of liver	0.007	0.993	0.000
C22.4 Other sarcomas of liver	0.007	0.993	0.000
C22.3 Angiosarcoma of liver	0.007	0.993	0.000
C22.2 Hepatoblastoma	0.007	0.993	0.000
J93.1 Other spontaneous pneumothorax	0.000	0.993	0.007
N28.9 Disorder of kidney and ureter, unspecified	0.000	0.993	0.007
J93 Pneumothorax	0.000	0.993	0.007
R74.8 Abnormal levels of other serum enzymes	0.006	0.994	0.000
H04.1 Other disorders of lachrymal gland	0.006	0.994	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.006	0.994	0.000
K76.6 Portal hypertension	0.006	0.994	0.000
R74 Abnormal serum enzyme levels	0.006	0.994	0.000
R74.9 Abnormal level of unspecified serum enzyme	0.005	0.995	0.000
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]	0.005	0.995	0.000
J93.0 Spontaneous tension pneumothorax	0.000	0.995	0.005
J33.9 Nasal polyp, unspecified	0.000	0.995	0.005
I47.9 Paroxysmal tachycardia, unspecified	0.005	0.995	0.000
K76.9 Liver disease, unspecified	0.005	0.995	0.000
J93.8 Other pneumothorax	0.000	0.995	0.005
I47 Paroxysmal tachycardia	0.005	0.995	0.000
S09.9 Unspecified injury of head	0.005	0.995	0.000
J39 Other diseases of upper respiratory tract	0.005	0.995	0.000
N88.2 Stricture and stenosis of cervix uteri	0.004	0.996	0.000
M19.93 Arthrosis, unspecified (Forearm)	0.000	0.996	0.004
D63.8 Anaemia in other chronic diseases classified elsewhere	0.000	0.996	0.004
M54.46 Lumbago with sciatica (Lumbar region)	0.000	0.996	0.004
J39.0 Retropharyngeal and parapharyngeal abscess	0.004	0.996	0.000
K76.8 Other specified diseases of liver	0.004	0.996	0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.000	0.996	0.004
K65 Peritonitis	0.000	0.996	0.004
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified	0.004	0.996	0.000
H40.9 Glaucoma, unspecified	0.000	0.996	0.004
M54.49 Lumbago with sciatica (Site unspecified)	0.000	0.996	0.004
J39.9 Disease of upper respiratory tract, unspecified	0.003	0.996	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.004	0.996	0.000
C71.2 Temporal lobe	0.003	0.997	0.000
H06.2 Dysthyroid exophthalmos	0.000	0.997	0.003
B18 Chronic viral hepatitis	0.003	0.997	0.000
I47.0 Reentry ventricular arrhythmia	0.003	0.997	0.000
R04.2 Haemoptysis	0.000	0.997	0.003
L84 Corns and callosities	0.000	0.997	0.003
Z83.7 Family history of diseases of the digestive system	0.000	0.997	0.003
M54.4 Lumbago with sciatica	0.000	0.997	0.003
T88.7 Unspecified adverse effect of drug or medicament	0.003	0.997	0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.003	0.997	0.000
C71.8 Overlapping lesion of brain	0.003	0.997	0.000
J39.1 Other abscess of pharynx	0.003	0.997	0.000
C71 Malignant neoplasm of brain	0.003	0.997	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.000	0.997	0.003
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.003	0.997	0.000
K65.9 Peritonitis, unspecified	0.000	0.997	0.003
M54.47 Lumbago with sciatica (Lumbosacral region)	0.000	0.997	0.003
M19.94 Arthrosis, unspecified (Hand)	0.000	0.997	0.003
M19.90 Arthrosis, unspecified (Multiple sites)	0.000	0.997	0.003
C71.0 Cerebrum, except lobes and ventricles	0.003	0.997	0.000
K04.5 Chronic apical periodontitis	0.000	0.997	0.003
R79.9 Abnormal finding of blood chemistry, unspecified	0.003	0.997	0.000
J33 Nasal polyp	0.000	0.997	0.003
M19.9 Arthrosis, unspecified	0.000	0.997	0.003
W07.9 Unspecified place	0.000	0.997	0.003
C71.1 Frontal lobe	0.003	0.997	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.003	0.997	0.000
D63.0 Anaemia in neoplastic disease	0.000	0.997	0.003
J33.0 Polyp of nasal cavity	0.000	0.997	0.003
B18.8 Other chronic viral hepatitis	0.003	0.997	0.000
B18.0 Chronic viral hepatitis B with delta-agent	0.003	0.997	0.000
C71.6 Cerebellum	0.003	0.997	0.000
G44.0 Cluster headache syndrome	0.000	0.997	0.003
C71.3 Parietal lobe	0.003	0.997	0.000
C71.7 Brain stem	0.003	0.997	0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.000	0.997	0.003
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.000	0.997	0.003
M54.44 Lumbago with sciatica-Thoracic	0.000	0.997	0.003
M54.43 Lumbago with sciatica-Cervicothoracic	0.000	0.997	0.003
M54.42 Lumbago with sciatica-Cervical	0.000	0.997	0.003
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.000	0.997	0.003
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.000	0.997	0.003
B18.9 Chronic viral hepatitis, unspecified	0.002	0.997	0.000
J39.2 Other diseases of pharynx	0.003	0.997	0.000
R85.5 Abnormal microbiological findings	0.003	0.997	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.000	0.997	0.002
C71.9 Brain, unspecified	0.003	0.997	0.000
C71.5 Cerebral ventricle	0.002	0.997	0.000
N20.9 Urinary calculus, unspecified	0.002	0.997	0.000
M40.24 Other and unspecified kyphosis (Thoracic region)	0.000	0.998	0.002
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.998	0.002
M93.9 Osteochondropathy, unspecified	0.000	0.998	0.002
Y40.8 Other systemic antibiotics	0.002	0.998	0.000
H01.0 Blepharitis	0.000	0.998	0.002
C71.4 Occipital lobe	0.002	0.998	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.002	0.998	0.000
J33.8 Other polyp of sinus	0.000	0.998	0.002
C62.9 Testis, unspecified	0.002	0.998	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.002	0.998	0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.002	0.998	0.000
R85.7 Abnormal histological findings	0.002	0.998	0.000
G45.3 Amaurosis fugax	0.000	0.998	0.002
B17 Other acute viral hepatitis	0.002	0.998	0.000
C17.0 Duodenum	0.000	0.998	0.002
F41.2 Mixed anxiety and depressive disorder	0.000	0.998	0.002
B17.1 Acute hepatitis C	0.002	0.998	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.998	0.002
K91.4 Colostomy and enterostomy malfunction	0.000	0.998	0.002
Y77.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
B17.9 Acute viral hepatitis, unspecified	0.002	0.998	0.000
R85.9 Unspecified abnormal finding	0.002	0.998	0.000
C17.1 Jejunum	0.000	0.998	0.002
T88.5 Other complications of anaesthesia	0.002	0.998	0.000
D60-D64 Aplastic and other anaemias	0.000	0.998	0.002
R79.0 Abnormal level of blood mineral	0.002	0.998	0.000
C17.9 Small intestine, unspecified	0.000	0.998	0.002
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.002	0.998	0.000
B17.2 Acute hepatitis E	0.002	0.998	0.000
J33.1 Polypoid sinus degeneration	0.000	0.998	0.002
R85.8 Other abnormal findings	0.002	0.998	0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.000	0.998	0.002
K65.8 Other peritonitis	0.000	0.998	0.002
T88.3 Malignant hyperthermia due to anaesthesis	0.002	0.998	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.002	0.998	0.000
T88.0 Infection following immunisation	0.002	0.998	0.000
Z57.2 Occupational exposure to dust	0.002	0.998	0.000
M25.78 Osteophyte (Other)	0.000	0.998	0.002
G24.9 Dystonia, unspecified	0.002	0.998	0.000
T88.9 Complication of surgical and medical care, unspecified	0.002	0.998	0.000
C17 Malignant neoplasm of small intestine	0.000	0.998	0.002
R04 Haemorrhage from respiratory passages	0.000	0.998	0.002
E03.9 Hypothyroidism, unspecified	0.000	0.998	0.002
G24.1 Idiopathic familial dystonia	0.002	0.998	0.000
S40.0 Contusion of shoulder and upper arm	0.002	0.998	0.000
O42.9 Premature rupture of membranes, unspecified	0.002	0.998	0.000
N30.0 Acute cystitis	0.002	0.998	0.000
R04.0 Epistaxis	0.000	0.998	0.002
R85.6 Abnormal cytological findings	0.002	0.998	0.000
R85.4 Abnormal immunological findings	0.002	0.998	0.000
R85.3 Abnormal level of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
R85.2 Abnormal level of other drugs, medicaments and biological substances	0.002	0.998	0.000
R85.1 Abnormal level of hormones	0.002	0.998	0.000
R85.0 Abnormal level of enzymes	0.002	0.998	0.000
S50.9 Superficial injury of forearm, unspecified	0.002	0.998	0.000
K72 Hepatic failure, not elsewhere classified	0.002	0.998	0.000
C17.2 Ileum	0.000	0.998	0.002
F11.2 Dependence syndrome	0.002	0.998	0.000
H16.0 Corneal ulcer	0.002	0.998	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.000	0.998	0.002
D51 Vitamin B12 deficiency anaemia	0.000	0.998	0.002
B15-B19 Viral hepatitis	0.002	0.998	0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.002	0.998	0.000
M19.92 Arthrosis, unspecified (Upper arm)	0.000	0.998	0.002
M00.9 Pyogenic arthritis, unspecified	0.002	0.998	0.000
Z02.8 Other examinations for administrative purposes	0.000	0.998	0.002
M24.27 Disorder of ligament (Ankle and foot)	0.002	0.998	0.000
B17.0 Acute delta-(super) infection of hepatitis B carrier	0.002	0.998	0.000
B18.1 Chronic viral hepatitis B without delta-agent	0.001	0.998	0.000
K12.2 Cellulitis and abscess of mouth	0.000	0.998	0.002
Y40.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
K72.0 Acute and subacute hepatic failure	0.002	0.998	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.002	0.998	0.000
G24.8 Other dystonia	0.002	0.998	0.000
K72.1 Chronic hepatic failure	0.002	0.998	0.000
N60.0 Solitary cyst of breast	0.002	0.998	0.000
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
Y40.5 Aminoglycosides	0.002	0.998	0.000
K70-K77 Diseases of liver	0.002	0.998	0.000
S82.60 Fracture of lateral malleolus (closed)	0.000	0.998	0.002
N31.0 Uninhibited neuropathic bladder, not elsewhere classified	0.002	0.998	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.002	0.998	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.000	0.998	0.002
G24 Dystonia	0.002	0.998	0.000
Y40 Systemic antibiotics	0.002	0.998	0.000
K72.9 Hepatic failure, unspecified	0.002	0.998	0.000
T88.4 Failed or difficult intubation	0.002	0.998	0.000
D62 Acute posthaemorrhagic anaemia	0.000	0.998	0.002
K77 Liver disorders in diseases classified elsewhere	0.002	0.998	0.000
M00.94 Pyogenic arthritis, unspecified (Hand)	0.002	0.998	0.000
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
C17.8 Overlapping lesion of small intestine	0.000	0.998	0.001
C17.3 Meckel's diverticulum	0.000	0.998	0.001
C25.9 Pancreas, unspecified	0.000	0.998	0.002
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.998	0.002
K71 Toxic liver disease	0.002	0.998	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
B17.8 Other specified acute viral hepatitis	0.001	0.998	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.002	0.998	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
R04.9 Haemorrhage from respiratory passages, unspecified	0.000	0.998	0.001
R04.1 Haemorrhage from throat	0.000	0.998	0.002
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.000	0.998	0.002
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.002	0.998	0.000
Z93.5 Cystostomy status	0.000	0.998	0.002
E27.8 Other specified disorders of adrenal gland	0.000	0.998	0.002
Y40.3 Macrolides	0.002	0.998	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
C18.7 Sigmoid colon	0.000	0.998	0.002
D51.2 Transcobalamin II deficiency	0.000	0.998	0.001
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.998	0.001
G24.0 Drug-induced dystonia	0.001	0.998	0.000
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.001	0.998	0.000
T88.2 Shock due to anaesthesia	0.001	0.998	0.000
M00.98 Pyogenic arthritis, unspecified (Other)	0.001	0.998	0.000
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.001	0.998	0.000
A41.8 Other specified septicaemia	0.002	0.998	0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.000	0.998	0.002
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.998	0.002
B15 Acute hepatitis A	0.001	0.998	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.000	0.998	0.001
R04.8 Haemorrhage from other sites in respiratory passages	0.000	0.998	0.001
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.001	0.998	0.000
G24.3 Spasmodic torticollis	0.001	0.998	0.000
L57.5 Actinic granuloma	0.001	0.998	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.002	0.998	0.000
F84.5 Asperger's syndrome	0.000	0.998	0.001
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.998	0.002
N85.9 Noninflammatory disorder of uterus, unspecified	0.002	0.998	0.000
Y40.4 Tetracyclines	0.001	0.998	0.000
Z98.2 Presence of cerebrospinal fluid drainage device	0.001	0.998	0.000
M00.99 Pyogenic arthritis, unspecified (Site unspecified)	0.001	0.999	0.000
D60.8 Other acquired pure red cell aplasias	0.000	0.999	0.001
D60.1 Transient acquired pure red cell aplasia	0.000	0.999	0.001
D60.0 Chronic acquired pure red cell aplasia	0.000	0.999	0.001
G24.4 Idiopathic orofacial dystonia	0.001	0.999	0.000
G24.2 Idiopathic nonfamilial dystonia	0.001	0.999	0.000
I42.6 Alcoholic cardiomyopathy	0.001	0.999	0.000
I47.2 Ventricular tachycardia	0.001	0.999	0.000
Y40.2 Chloramphenicol group	0.001	0.999	0.000
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.001	0.999	0.000
K71.0 Toxic liver disease with cholestasis	0.001	0.999	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.001	0.999	0.000
Z57.3 Occupational exposure to other air contaminants	0.001	0.999	0.000
M93 Other osteochondropathies	0.000	0.999	0.001
K71.9 Toxic liver disease, unspecified	0.001	0.999	0.000
K71.8 Toxic liver disease with other disorders of liver	0.001	0.999	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.001	0.999	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.001	0.999	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.001	0.999	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.001	0.999	0.000
K71.2 Toxic liver disease with acute hepatitis	0.001	0.999	0.000
M00.93 Pyogenic arthritis, unspecified (Forearm)	0.001	0.999	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.999	0.001
D60.9 Acquired pure red cell aplasia, unspecified	0.000	0.999	0.001
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.999	0.001
G24.5 Blepharospasm	0.001	0.999	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.000	0.999	0.001
Y40.0 Penicillins	0.001	0.999	0.000
D61 Other aplastic anaemias	0.000	0.999	0.001
R79 Other abnormal findings of blood chemistry	0.001	0.999	0.000
S09 Other and unspecified injuries of head	0.001	0.999	0.000
M93.1 Kienbock's disease of adults	0.000	0.999	0.001
S09.0 Injury of blood vessels of head, not elsewhere classified	0.001	0.999	0.000
C62.1 Descended testis	0.001	0.999	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.999	0.001
K71.1 Toxic liver disease with hepatic necrosis	0.001	0.999	0.000
A41.4 Septicaemia due to anaerobes	0.001	0.999	0.000
B15.0 Hepatitis A with hepatic coma	0.001	0.999	0.000
H06.3 Other disorders of orbit in diseases classified elsewhere	0.000	0.999	0.001
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.000	0.999	0.001
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.000	0.999	0.001
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.001	0.999	0.000
R44.3 Hallucinations, unspecified	0.000	0.999	0.001
B19 Unspecified viral hepatitis	0.001	0.999	0.000
C34.3 Lower lobe, bronchus or lung	0.000	0.999	0.001
M33.1 Other dermatomyositis	0.000	0.999	0.001
S01.9 Open wound of head, part unspecified	0.000	0.999	0.001
B16 Acute hepatitis B	0.001	0.999	0.000
M19.98 Arthrosis, unspecified (Other)	0.000	0.999	0.001
D11.7 Other major salivary glands	0.000	0.999	0.001
D16.2 Long bones of lower limb	0.001	0.999	0.000
L57.4 Cutis laxa senilis	0.001	0.999	0.000
L57.3 Poikiloderma of Civatte	0.001	0.999	0.000
L57.2 Cutis rhomboidalis nuchae	0.001	0.999	0.000
L57.1 Actinic reticuloid	0.001	0.999	0.000
M40.2 Other and unspecified kyphosis	0.000	0.999	0.001
Y40.6 Rifamycins	0.001	0.999	0.000
M24.23 Disorder of ligament (Forearm)	0.001	0.999	0.000
M40.22 Other and unspecified kyphosis (Cervical region)	0.000	0.999	0.001
G70.0 Myasthenia gravis	0.000	0.999	0.001
H81.0 Meniere's disease	0.000	0.999	0.001
C62 Malignant neoplasm of testis	0.001	0.999	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.001	0.999	0.000
H18.8 Other specified disorders of cornea	0.000	0.999	0.001
M93.8 Other specified osteochondropathies	0.000	0.999	0.001
M93.2 Osteochondritis dissecans	0.000	0.999	0.001
M93.0 Slipped upper femoral epiphysis (nontraumatic)	0.000	0.999	0.001
O62.2 Other uterine inertia	0.000	0.999	0.001
D50-D53 Nutritional anaemias	0.000	0.999	0.001
S62.61 Fracture of other finger (open)	0.001	0.999	0.000
B15.9 Hepatitis A without hepatic coma	0.001	0.999	0.000
D61.8 Other specified aplastic anaemias	0.000	0.999	0.001
D61.3 Idiopathic aplastic anaemia	0.000	0.999	0.001
D61.2 Aplastic anaemia due to other external agents	0.000	0.999	0.001
S09.1 Injury of muscle and tendon of head	0.001	0.999	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.000	0.999	0.001
M40.25 Other and unspecified kyphosis (Thoracolumbar region)	0.000	0.999	0.001
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.999	0.001
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.001	0.999	0.000
D61.0 Constitutional aplastic anaemia	0.000	0.999	0.001
H01.9 Inflammation of eyelid, unspecified	0.001	0.999	0.000
K73.9 Chronic hepatitis, unspecified	0.001	0.999	0.000
Q87.4 Marfan's syndrome	0.001	0.999	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.000	0.999	0.001
A41 Other septicaemia	0.001	0.999	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.001	0.999	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.001	0.999	0.000
F60.8 Other specific personality disorders	0.000	0.999	0.001
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.000	0.999	0.001
K05.3 Chronic periodontitis	0.000	0.999	0.001
Q18.0 Sinus, fistula and cyst of branchial cleft	0.001	0.999	0.000
S09.2 Traumatic rupture of ear drum	0.001	0.999	0.000
K73 Chronic hepatitis, not elsewhere classified	0.001	0.999	0.000
Y77 Ophthalmic devices associated with adverse incidents	0.001	0.999	0.000
B16.2 Acute hepatitis B without delta-agent with hepatic coma	0.001	0.999	0.000
B16.1 Acute hepatitis B with delta-agent (coinfection) without hepatic coma	0.001	0.999	0.000
B16.0 Acute hepatitis B with delta-agent (coinfection) with hepatic coma	0.001	0.999	0.000
B19.0 Unspecified viral hepatitis with coma	0.001	0.999	0.000
S09.7 Multiple injuries of head	0.001	0.999	0.000
M40.28 Other and unspecified kyphosis (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M40.27 Other and unspecified kyphosis (Lumbosacral region)	0.000	0.999	0.001
M40.23 Other and unspecified kyphosis (Cervicothoracic region)	0.000	0.999	0.001
M40.21 Other and unspecified kyphosis (Occipito-atlanto-axial region)	0.000	0.999	0.001
M40.20 Other and unspecified kyphosis (Multiple sites in spine)	0.000	0.999	0.001
C62.0 Undescended testis	0.001	0.999	0.000
D48.6 Breast	0.000	0.999	0.001
Z73.8 Other problems related to life-management difficulty	0.000	0.999	0.001
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.001	0.999	0.000
D55-D59 Haemolytic anaemias	0.000	0.999	0.001
M93.26 Osteochondritis dissecans knee	0.000	0.999	0.001
M93.86 Other specified osteochondropathies, lower leg	0.000	0.999	0.001
M94.26 Chondromalacia (Lower leg)	0.001	0.999	0.000
N97.1 Female infertility of tubal origin	0.001	0.999	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.000	0.999	0.001
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.000	0.999	0.001
F60.3 Emotionally unstable personality disorder	0.000	0.999	0.001
E27 Other disorders of adrenal gland	0.000	0.999	0.001
A41.3 Septicaemia due to Haemophilus influenzae	0.001	0.999	0.000
C69.4 Ciliary body	0.001	0.999	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.001	0.999	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.001	0.999	0.000
Y77.2 Prosthetic and other implants, materials and accessory devices	0.001	0.999	0.000
S72.20 Subtrochanteric fracture (closed)	0.000	0.999	0.001
C69.2 Retina	0.001	0.999	0.000
D61.9 Aplastic anaemia, unspecified	0.000	0.999	0.001
G06.1 Intraspinal abscess and granuloma	0.001	0.999	0.000
Y77.8 Miscellaneous devices, not elsewhere classified	0.001	0.999	0.000
Y77.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.999	0.000
Y77.0 Diagnostic and monitoring devices	0.001	0.999	0.000
Z04.9 Examination and observation for unspecified reason	0.000	0.999	0.001
M40.26 Other and unspecified kyphosis (Lumbar region)	0.000	0.999	0.001
S62.20 Fracture of first metacarpal bone (closed)	0.001	0.999	0.000
C25.3 Pancreatic duct	0.000	0.999	0.001
C72.9 Central nervous system, unspecified	0.001	0.999	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.001	0.999	0.000
C72.5 Other and unspecified cranial nerves	0.001	0.999	0.000
C72.4 Acoustic nerve	0.001	0.999	0.000
C72.3 Optic nerve	0.001	0.999	0.000
C72.2 Olfactory nerve	0.001	0.999	0.000
C72.1 Cauda equina	0.001	0.999	0.000
C72.0 Spinal cord	0.001	0.999	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.999	0.001
H54.4 Blindness, one eye	0.000	0.999	0.001
I12.0 Hypertensive renal disease with renal failure	0.000	0.999	0.001
O41.8 Other specified disorders of amniotic fluid and membranes	0.000	0.999	0.001
R89.0 Abnormal level of enzymes	0.001	0.999	0.000
C70 Malignant neoplasm of meninges	0.001	0.999	0.000
D55 Anaemia due to enzyme disorders	0.000	0.999	0.001
C69.6 Orbit	0.001	0.999	0.000
E27.5 Adrenomedullary hyperfunction	0.000	0.999	0.001
E27.0 Other adrenocortical overactivity	0.000	0.999	0.001
M00 Pyogenic arthritis	0.001	0.999	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.000	0.999	0.001
M00.06 Staphylococcal arthritis and polyarthritis (Lower leg)	0.001	0.999	0.000
M84.01 Malunion of fracture (Shoulder region)	0.000	0.999	0.001
C25.0 Head of pancreas	0.000	0.999	0.001
C76.0 Head, face and neck	0.001	0.999	0.000
D68.9 Coagulation defect, unspecified	0.000	0.999	0.001
F40.0 Agoraphobia	0.001	0.999	0.000
G45.1 Carotid artery syndrome (hemispheric)	0.000	0.999	0.001
M00.0 Staphylococcal arthritis and polyarthritis	0.001	0.999	0.000
R89.6 Abnormal cytological findings	0.001	0.999	0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.000	0.999	0.001
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.001	0.999	0.000
D53 Other nutritional anaemias	0.000	0.999	0.001
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.001	0.999	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.000	0.999	0.001
D55.8 Other anaemias due to enzyme disorders	0.000	0.999	0.001
D55.3 Anaemia due to disorders of nucleotide metabolism	0.000	0.999	0.001
D55.2 Anaemia due to disorders of glycolytic enzymes	0.000	0.999	0.001
D55.1 Anaemia due to other disorders of glutathione metabolism	0.000	0.999	0.001
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.000	0.999	0.001
M00.8 Arthritis and polyarthritis due to other specified bacterial agents	0.001	0.999	0.000
N76.6 Ulceration of vulva	0.000	0.999	0.001
R89.9 Unspecified abnormal finding	0.001	0.999	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.001	0.999	0.000
C69 Malignant neoplasm of eye and adnexa	0.001	0.999	0.000
D57 Sickle-cell disorders	0.000	0.999	0.001
C70.9 Meninges, unspecified	0.001	0.999	0.000
C70.1 Spinal meninges	0.001	0.999	0.000
D61.1 Drug-induced aplastic anaemia	0.000	0.999	0.001
F84.0 Childhood autism	0.000	0.999	0.001
G60.0 Hereditary motor and sensory neuropathy	0.000	0.999	0.001
M00.2 Other streptococcal arthritis and polyarthritis	0.001	0.999	0.000
M00.1 Pneumococcal arthritis and polyarthritis	0.001	0.999	0.000
S91.3 Open wound of other parts of foot	0.000	0.999	0.001
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.000	0.999	0.001
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.000	0.999	0.001
D56 Thalassaemia	0.000	0.999	0.001
W07 Fall involving chair	0.000	0.999	0.001
M00.09 Staphylococcal arthritis and polyarthritis (Site unspecified)	0.001	0.999	0.000
M00.08 Staphylococcal arthritis and polyarthritis (Other)	0.001	0.999	0.000
M00.07 Staphylococcal arthritis and polyarthritis (Ankle and foot)	0.001	0.999	0.000
M00.05 Staphylococcal arthritis and polyarthritis (Pelvic region and thigh)	0.001	0.999	0.000
M00.04 Staphylococcal arthritis and polyarthritis (Hand)	0.001	0.999	0.000
M00.03 Staphylococcal arthritis and polyarthritis (Forearm)	0.001	0.999	0.000
M00.02 Staphylococcal arthritis and polyarthritis (Upper arm)	0.001	0.999	0.000
M00.01 Staphylococcal arthritis and polyarthritis (Shoulder region)	0.001	0.999	0.000
M00.00 Staphylococcal arthritis and polyarthritis (Multiple sites)	0.001	0.999	0.000
M00.86 Arthritis and polyarthritis due to other specified bacterial agents (Lower leg)	0.001	0.999	0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.001	0.999	0.000
M19.97 Arthrosis, unspecified (Ankle and foot)	0.000	0.999	0.001
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.001	0.999	0.000
D53.8 Other specified nutritional anaemias	0.000	0.999	0.001
D53.2 Scorbutic anaemia	0.000	0.999	0.001
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.000	0.999	0.001
D53.0 Protein deficiency anaemia	0.000	0.999	0.001
F40.8 Other phobic anxiety disorders	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations