TreeWAS – Variant ID: rs4578395

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K82.4 Cholesterolosis of gallbladder	0.000	0.758	0.242
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.981	0.019
K62.5 Haemorrhage of anus and rectum	0.016	0.984	0.000
I69 Sequelae of cerebrovascular disease	0.000	0.984	0.016
M84.03 Malunion of fracture (Forearm)	0.016	0.984	0.000
M84.0 Malunion of fracture	0.015	0.985	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.015	0.985	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.015	0.985	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.014	0.986	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.986	0.014
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.986	0.014
M84 Disorders of continuity of bone	0.014	0.986	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.014	0.986	0.000
C77.1 Intrathoracic lymph nodes	0.000	0.987	0.013
M84.06 Malunion of fracture (Lower leg)	0.013	0.987	0.000
I69.3 Sequelae of cerebral infarction	0.000	0.987	0.013
M84.02 Malunion of fracture (Upper arm)	0.012	0.988	0.000
M84.04 Malunion of fracture (Hand)	0.012	0.988	0.000
F41.9 Anxiety disorder, unspecified	0.000	0.988	0.012
M84.01 Malunion of fracture (Shoulder region)	0.012	0.988	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.012	0.988	0.000
Z51.3 Blood transfusion without reported diagnosis	0.000	0.988	0.012
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.989	0.011
M84.2 Delayed union of fracture	0.011	0.989	0.000
M84.09 Malunion of fracture (Site unspecified)	0.011	0.989	0.000
M84.00 Malunion of fracture (Multiple sites)	0.011	0.989	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.011	0.989	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.011	0.989	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.011	0.989	0.000
M84.08 Malunion of fracture (Other)	0.011	0.989	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.011	0.989	0.000
M84.4 Pathological fracture, not elsewhere classified	0.011	0.989	0.000
M84.9 Disorder of continuity of bone, unspecified	0.010	0.990	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.990	0.010
M84.8 Other disorders of continuity of bone	0.010	0.990	0.000
M84.3 Stress fracture, not elsewhere classified	0.010	0.990	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.010	0.990	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.010	0.990	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.010	0.990	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.009	0.991	0.000
M84.22 Delayed union of fracture (Upper arm)	0.009	0.991	0.000
D48.1 Connective and other soft tissue	0.000	0.991	0.009
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.008	0.992	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.008	0.992	0.000
M84.28 Delayed union of fracture (Other)	0.008	0.992	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.008	0.992	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.008	0.992	0.000
M84.24 Delayed union of fracture (Hand)	0.008	0.992	0.000
M84.23 Delayed union of fracture (Forearm)	0.008	0.992	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.008	0.992	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.008	0.992	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.008	0.992	0.000
M84.26 Delayed union of fracture (Lower leg)	0.008	0.992	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.008	0.992	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.008	0.992	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.008	0.992	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.008	0.992	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.008	0.992	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.008	0.992	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.008	0.992	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.008	0.992	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.008	0.992	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.008	0.992	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.008	0.992	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.008	0.992	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.008	0.992	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.008	0.992	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.008	0.992	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.008	0.992	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.007	0.992	0.000
M84.88 Other disorders of continuity of bone (Other)	0.007	0.992	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.007	0.992	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.007	0.992	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.007	0.992	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.007	0.992	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.007	0.992	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.007	0.992	0.000
K29.1 Other acute gastritis	0.000	0.992	0.008
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.007	0.992	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.007	0.992	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.007	0.992	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.007	0.992	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.007	0.992	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.007	0.992	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.007	0.992	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.007	0.992	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.007	0.992	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.007	0.992	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.007	0.992	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.007	0.993	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.007	0.993	0.000
M79.62 Pain in limb (Upper arm)	0.007	0.993	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.994	0.006
K02.9 Dental caries, unspecified	0.000	0.994	0.006
N32.1 Vesicointestinal fistula	0.000	0.994	0.006
D48.5 Skin	0.000	0.994	0.006
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.005	0.994	0.000
H18.8 Other specified disorders of cornea	0.005	0.994	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.995	0.005
E78.2 Mixed hyperlipidaemia	0.000	0.995	0.005
H18.1 Bullous keratopathy	0.005	0.995	0.000
G31.0 Circumscribed brain atrophy	0.000	0.995	0.005
K82 Other diseases of gallbladder	0.000	0.995	0.005
H18 Other disorders of cornea	0.005	0.995	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.000	0.995	0.005
M22.2 Patellofemoral disorders	0.000	0.995	0.005
H57.9 Disorder of eye and adnexa, unspecified	0.000	0.995	0.005
H18.6 Keratoconus	0.004	0.996	0.000
H18.5 Hereditary corneal dystrophies	0.004	0.996	0.000
G31.2 Degeneration of nervous system due to alcohol	0.000	0.996	0.004
H18.9 Disorder of cornea, unspecified	0.004	0.996	0.000
L90.5 Scar conditions and fibrosis of skin	0.004	0.996	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.996	0.004
I65.2 Occlusion and stenosis of carotid artery	0.004	0.996	0.000
G30 Alzheimer's disease	0.000	0.996	0.004
G30.1 Alzheimer's disease with late onset	0.000	0.996	0.004
G30.0 Alzheimer's disease with early onset	0.000	0.996	0.004
J02.9 Acute pharyngitis, unspecified	0.000	0.996	0.004
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.000	0.996	0.004
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.996	0.004
K82.2 Perforation of gallbladder	0.000	0.996	0.004
G31.8 Other specified degenerative diseases of nervous system	0.000	0.996	0.004
H18.7 Other corneal deformities	0.004	0.996	0.000
G30-G32 Other degenerative diseases of the nervous system	0.000	0.996	0.004
D48.3 Retroperitoneum	0.000	0.996	0.004
H18.0 Corneal pigmentations and deposits	0.004	0.996	0.000
D48.4 Peritoneum	0.000	0.996	0.004
D48.2 Peripheral nerves and autonomic nervous system	0.000	0.996	0.004
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.000	0.996	0.004
D28.0 Vulva	0.004	0.996	0.000
M86.9 Osteomyelitis, unspecified	0.000	0.996	0.004
N87.1 Moderate cervical dysplasia	0.004	0.996	0.000
S70.1 Contusion of thigh	0.000	0.996	0.004
S70.0 Contusion of hip	0.000	0.996	0.004
D48.7 Other specified sites	0.000	0.996	0.003
H18.3 Changes in corneal membranes	0.003	0.996	0.000
H18.2 Other corneal oedema	0.003	0.997	0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
S70 Superficial injury of hip and thigh	0.000	0.997	0.003
K57.1 Diverticular disease of small intestine without perforation or abscess	0.000	0.997	0.003
H18.4 Corneal degeneration	0.003	0.997	0.000
R31 Unspecified haematuria	0.000	0.997	0.003
D48.6 Breast	0.000	0.997	0.003
K82.1 Hydrops of gallbladder	0.000	0.997	0.003
J93.8 Other pneumothorax	0.000	0.997	0.003
M86.94 Osteomyelitis, unspecified (Hand)	0.000	0.997	0.003
M86.6 Other chronic osteomyelitis	0.000	0.997	0.003
G30.9 Alzheimer's disease, unspecified	0.000	0.997	0.003
S20.8 Superficial injuries of other and unspecified parts of thorax	0.000	0.997	0.003
M86.66 Other chronic osteomyelitis (Lower leg)	0.000	0.997	0.003
S72.40 Fracture of lower end of femur (closed)	0.000	0.997	0.003
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.997	0.003
S70.9 Superficial injury of hip and thigh, unspecified	0.000	0.997	0.003
M86 Osteomyelitis	0.000	0.997	0.003
F41 Other anxiety disorders	0.000	0.997	0.003
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.997	0.003
K82.0 Obstruction of gallbladder	0.000	0.997	0.003
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.003	0.997	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.997	0.003
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.003	0.997	0.000
J93 Pneumothorax	0.000	0.997	0.003
M24.27 Disorder of ligament (Ankle and foot)	0.003	0.997	0.000
J93.0 Spontaneous tension pneumothorax	0.000	0.997	0.003
M24.26 Disorder of ligament (Lower leg)	0.003	0.997	0.000
M86.93 Osteomyelitis, unspecified (Forearm)	0.000	0.997	0.003
M86.92 Osteomyelitis, unspecified (Upper arm)	0.000	0.997	0.003
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.000	0.997	0.003
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.000	0.997	0.003
E21.3 Hyperparathyroidism, unspecified	0.003	0.997	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.997	0.003
G30.8 Other Alzheimer's disease	0.000	0.997	0.003
M86.98 Osteomyelitis, unspecified (Other)	0.000	0.997	0.003
M86.8 Other osteomyelitis	0.000	0.997	0.003
J93.9 Pneumothorax, unspecified	0.000	0.997	0.003
M24.2 Disorder of ligament	0.003	0.997	0.000
J93.1 Other spontaneous pneumothorax	0.000	0.997	0.003
M85.8 Other specified disorders of bone density and structure	0.003	0.997	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.997	0.003
N36.8 Other specified disorders of urethra	0.000	0.997	0.003
M85 Other disorders of bone density and structure	0.003	0.997	0.000
M86.69 Other chronic osteomyelitis (Site unspecified)	0.000	0.997	0.003
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)	0.000	0.997	0.003
M86.96 Osteomyelitis, unspecified (Lower leg)	0.000	0.997	0.003
K02 Dental caries	0.000	0.997	0.003
M86.86 Other osteomyelitis (Lower leg)	0.000	0.997	0.003
C64 Malignant neoplasm of kidney, except renal pelvis	0.000	0.997	0.003
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.000	0.997	0.003
S70.7 Multiple superficial injuries of hip and thigh	0.000	0.997	0.003
M86.67 Other chronic osteomyelitis (Ankle and foot)	0.000	0.997	0.003
S72.4 Fracture of lower end of femur	0.000	0.997	0.003
M89.09 Algoneurodystrophy (Site unspecified)	0.000	0.997	0.003
F41.8 Other specified anxiety disorders	0.000	0.997	0.003
K82.3 Fistula of gallbladder	0.001	0.997	0.002
M24.28 Disorder of ligament (Other)	0.002	0.997	0.000
M24.23 Disorder of ligament (Forearm)	0.002	0.997	0.000
M86.64 Other chronic osteomyelitis (Hand)	0.000	0.997	0.002
M86.63 Other chronic osteomyelitis (Forearm)	0.000	0.997	0.002
M86.62 Other chronic osteomyelitis (Upper arm)	0.000	0.997	0.002
M86.61 Other chronic osteomyelitis (Shoulder region)	0.000	0.997	0.002
M86.60 Other chronic osteomyelitis (Multiple sites)	0.000	0.997	0.002
E83.4 Disorders of magnesium metabolism	0.000	0.997	0.003
F41.3 Other mixed anxiety disorders	0.000	0.997	0.002
K82.9 Disease of gallbladder, unspecified	0.000	0.997	0.002
M23.49 Loose body in knee-Unspec lig/men	0.000	0.997	0.003
G45.3 Amaurosis fugax	0.003	0.997	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.002	0.997	0.000
K58.0 Irritable bowel syndrome with diarrhoea	0.000	0.997	0.003
M80-M85 Disorders of bone density and structure	0.003	0.997	0.000
I24.8 Other forms of acute ischaemic heart disease	0.000	0.998	0.002
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.002	0.998	0.000
M85.4 Solitary bone cyst	0.002	0.998	0.000
M86.5 Other chronic haematogenous osteomyelitis	0.000	0.998	0.002
M86.3 Chronic multifocal osteomyelitis	0.000	0.998	0.002
M86.2 Subacute osteomyelitis	0.000	0.998	0.002
M86.0 Acute haematogenous osteomyelitis	0.000	0.998	0.002
I22 Subsequent myocardial infarction	0.000	0.998	0.002
M24.21 Disorder of ligament (Shoulder region)	0.002	0.998	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.000	0.998	0.002
M86.4 Chronic osteomyelitis with draining sinus	0.000	0.998	0.002
M10.90 Gout, unspecified (Multiple sites)	0.002	0.998	0.000
M85.0 Fibrous dysplasia (monostotic)	0.002	0.998	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.002	0.998	0.000
M86.87 Other osteomyelitis (Ankle and foot)	0.000	0.998	0.002
O36.6 Maternal care for excessive foetal growth	0.000	0.998	0.002
S70.8 Other superficial injuries of hip and thigh	0.000	0.998	0.002
S72.41 Fracture of lower end of femur (open)	0.000	0.998	0.002
J15.0 Pneumonia due to Klebsiella pneumoniae	0.002	0.998	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.002	0.998	0.000
C77.5 Intrapelvic lymph nodes	0.000	0.998	0.002
M24.29 Disorder of ligament (Site unspecified)	0.002	0.998	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.002	0.998	0.000
M24.22 Disorder of ligament (Upper arm)	0.002	0.998	0.000
M24.20 Disorder of ligament (Multiple sites)	0.002	0.998	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.002	0.998	0.000
M86.89 Other osteomyelitis (Site unspecified)	0.000	0.998	0.002
M86.88 Other osteomyelitis (Other)	0.000	0.998	0.002
M86.84 Other osteomyelitis (Hand)	0.000	0.998	0.002
M86.83 Other osteomyelitis (Forearm)	0.000	0.998	0.002
M86.82 Other osteomyelitis (Upper arm)	0.000	0.998	0.002
M86.81 Other osteomyelitis (Shoulder region)	0.000	0.998	0.002
M86.80 Other osteomyelitis (Multiple sites)	0.000	0.998	0.002
M86.1 Other acute osteomyelitis	0.000	0.998	0.002
M85.84 Other specified disorders of bone density and structure (Hand)	0.002	0.998	0.000
D48.0 Bone and articular cartilage	0.000	0.998	0.002
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.998	0.002
M85.6 Other cyst of bone	0.002	0.998	0.000
M86.68 Other chronic osteomyelitis (Other)	0.000	0.998	0.002
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.002	0.998	0.000
K02.1 Caries of dentin	0.000	0.998	0.002
M85.5 Aneurysmal bone cyst	0.002	0.998	0.000
M85.3 Osteitis condensans	0.002	0.998	0.000
M85.1 Skeletal fluorosis	0.002	0.998	0.000
I22.8 Subsequent myocardial infarction of other sites	0.000	0.998	0.002
M85.47 Solitary bone cyst (Ankle and foot)	0.002	0.998	0.000
K02.5 Caries with pulp exposure	0.000	0.998	0.002
K02.4 Odontoclasia	0.000	0.998	0.002
K02.3 Arrested dental caries	0.000	0.998	0.002
K02.2 Caries of cementum	0.000	0.998	0.002
K02.0 Caries limited to enamel	0.000	0.998	0.002
M85.83 Other specified disorders of bone density and structure (Forearm)	0.002	0.998	0.000
M86.85 Other osteomyelitis (Pelvic region and thigh)	0.000	0.998	0.002
H49.0 Third [oculomotor] nerve palsy	0.000	0.998	0.002
M85.9 Disorder of bone density and structure, unspecified	0.002	0.998	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.002	0.998	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.998	0.002
S72 Fracture of femur	0.000	0.998	0.002
M24.55 Contracture of joint (Pelvic region and thigh)	0.002	0.998	0.000
G12.2 Motor neuron disease	0.002	0.998	0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.002	0.998	0.000
K02.8 Other dental caries	0.000	0.998	0.002
S72.9 Fracture of femur, part unspecified	0.000	0.998	0.002
S72.90 Fracture of femur, part unspecified (closed)	0.000	0.998	0.002
H47.1 Papilloedema, unspecified	0.000	0.998	0.002
M85.46 Solitary bone cyst (Lower leg)	0.002	0.998	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.002	0.998	0.000
M85.49 Solitary bone cyst (Site unspecified)	0.002	0.998	0.000
M85.48 Solitary bone cyst (Other)	0.002	0.998	0.000
M85.44 Solitary bone cyst (Hand)	0.002	0.998	0.000
M85.43 Solitary bone cyst (Forearm)	0.002	0.998	0.000
M85.42 Solitary bone cyst (Upper arm)	0.002	0.998	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.002	0.998	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.002	0.998	0.000
M89.03 Algoneurodystrophy (Forearm)	0.000	0.998	0.002
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.000	0.998	0.002
M89.0 Algoneurodystrophy	0.000	0.998	0.002
M86.09 Acute haematogenous osteomyelitis (Site unspecified)	0.000	0.998	0.002
M86.08 Acute haematogenous osteomyelitis (Other)	0.000	0.998	0.002
M86.07 Acute haematogenous osteomyelitis (Ankle and foot)	0.000	0.998	0.002
M86.06 Acute haematogenous osteomyelitis (Lower leg)	0.000	0.998	0.002
M86.05 Acute haematogenous osteomyelitis (Pelvic region and thigh)	0.000	0.998	0.002
M86.04 Acute haematogenous osteomyelitis (Hand)	0.000	0.998	0.002
M86.03 Acute haematogenous osteomyelitis (Forearm)	0.000	0.998	0.002
M86.02 Acute haematogenous osteomyelitis (Upper arm)	0.000	0.998	0.002
M86.01 Acute haematogenous osteomyelitis (Shoulder region)	0.000	0.998	0.002
M86.00 Acute haematogenous osteomyelitis (Multiple sites)	0.000	0.998	0.002
M86.29 Subacute osteomyelitis (Site unspecified)	0.000	0.998	0.002
M86.28 Subacute osteomyelitis (Other)	0.000	0.998	0.002
M86.27 Subacute osteomyelitis (Ankle and foot)	0.000	0.998	0.002
M86.26 Subacute osteomyelitis (Lower leg)	0.000	0.998	0.002
M86.25 Subacute osteomyelitis (Pelvic region and thigh)	0.000	0.998	0.002
M86.24 Subacute osteomyelitis (Hand)	0.000	0.998	0.002
M86.23 Subacute osteomyelitis (Forearm)	0.000	0.998	0.002
M86.22 Subacute osteomyelitis (Upper arm)	0.000	0.998	0.002
M86.21 Subacute osteomyelitis (Shoulder region)	0.000	0.998	0.002
M86.20 Subacute osteomyelitis (Multiple sites)	0.000	0.998	0.002
M86.39 Chronic multifocal osteomyelitis (Site unspecified)	0.000	0.998	0.002
M86.38 Chronic multifocal osteomyelitis (Other)	0.000	0.998	0.002
M86.37 Chronic multifocal osteomyelitis (Ankle and foot)	0.000	0.998	0.002
M86.36 Chronic multifocal osteomyelitis (Lower leg)	0.000	0.998	0.002
M86.35 Chronic multifocal osteomyelitis (Pelvic region and thigh)	0.000	0.998	0.002
M86.34 Chronic multifocal osteomyelitis (Hand)	0.000	0.998	0.002
M86.33 Chronic multifocal osteomyelitis (Forearm)	0.000	0.998	0.002
M86.32 Chronic multifocal osteomyelitis (Upper arm)	0.000	0.998	0.002
M86.31 Chronic multifocal osteomyelitis (Shoulder region)	0.000	0.998	0.002
M86.30 Chronic multifocal osteomyelitis (Multiple sites)	0.000	0.998	0.002
M86.59 Other chronic haematogenous osteomyelitis (Site unspecified)	0.000	0.998	0.002
M86.58 Other chronic haematogenous osteomyelitis (Other)	0.000	0.998	0.002
M86.57 Other chronic haematogenous osteomyelitis (Ankle and foot)	0.000	0.998	0.002
M86.56 Other chronic haematogenous osteomyelitis (Lower leg)	0.000	0.998	0.002
M86.55 Other chronic haematogenous osteomyelitis (Pelvic region and thigh)	0.000	0.998	0.002
M86.54 Other chronic haematogenous osteomyelitis (Hand)	0.000	0.998	0.002
M86.53 Other chronic haematogenous osteomyelitis (Forearm)	0.000	0.998	0.002
M86.52 Other chronic haematogenous osteomyelitis (Upper arm)	0.000	0.998	0.002
M86.51 Other chronic haematogenous osteomyelitis (Shoulder region)	0.000	0.998	0.002
M86.50 Other chronic haematogenous osteomyelitis (Multiple sites)	0.000	0.998	0.002
M85.2 Hyperostosis of skull	0.002	0.998	0.000
M24.54 Contracture of joint (Hand)	0.002	0.998	0.000
M86.49 Chronic osteomyelitis with draining sinus (Site unspecified)	0.000	0.998	0.002
M86.48 Chronic osteomyelitis with draining sinus (Other)	0.000	0.998	0.002
M86.47 Chronic osteomyelitis with draining sinus (Ankle and foot)	0.000	0.998	0.002
M86.45 Chronic osteomyelitis with draining sinus (Pelvic region and thigh)	0.000	0.998	0.002
M86.44 Chronic osteomyelitis with draining sinus (Hand)	0.000	0.998	0.002
M86.43 Chronic osteomyelitis with draining sinus (Forearm)	0.000	0.998	0.002
M86.42 Chronic osteomyelitis with draining sinus (Upper arm)	0.000	0.998	0.002
M86.41 Chronic osteomyelitis with draining sinus (Shoulder region)	0.000	0.998	0.002
M86.40 Chronic osteomyelitis with draining sinus (Multiple sites)	0.000	0.998	0.002
E20.9 Hypoparathyroidism, unspecified	0.000	0.998	0.002
M24.5 Contracture of joint	0.002	0.998	0.000
S72.8 Fractures of other parts of femur	0.000	0.998	0.002
Z45.8 Adjustment and management of other implanted devices	0.002	0.998	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.002	0.998	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.002	0.998	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.002	0.998	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.002	0.998	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.002	0.998	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.002	0.998	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.002	0.998	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.002	0.998	0.000
I45.5 Other specified heart block	0.000	0.998	0.002
K05.3 Chronic periodontitis	0.002	0.998	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.002	0.998	0.000
M83 Adult osteomalacia	0.002	0.998	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.002	0.998	0.000
M85.66 Other cyst of bone (Lower leg)	0.002	0.998	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.000	0.998	0.002
M89.55 Osteolysis (Pelvic region and thigh)	0.000	0.998	0.002
S72.3 Fracture of shaft of femur	0.000	0.998	0.002
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M85.69 Other cyst of bone (Site unspecified)	0.002	0.998	0.000
M85.63 Other cyst of bone (Forearm)	0.002	0.998	0.000
M85.62 Other cyst of bone (Upper arm)	0.002	0.998	0.000
M85.61 Other cyst of bone (Shoulder region)	0.002	0.998	0.000
M85.60 Other cyst of bone (Multiple sites)	0.002	0.998	0.000
M86.19 Other acute osteomyelitis (Site unspecified)	0.000	0.998	0.002
M86.18 Other acute osteomyelitis (Other)	0.000	0.998	0.002
M86.16 Other acute osteomyelitis (Lower leg)	0.000	0.998	0.002
M86.15 Other acute osteomyelitis (Pelvic region and thigh)	0.000	0.998	0.002
M86.14 Other acute osteomyelitis (Hand)	0.000	0.998	0.002
M86.13 Other acute osteomyelitis (Forearm)	0.000	0.998	0.002
M86.12 Other acute osteomyelitis (Upper arm)	0.000	0.998	0.002
M86.11 Other acute osteomyelitis (Shoulder region)	0.000	0.998	0.002
M86.10 Other acute osteomyelitis (Multiple sites)	0.000	0.998	0.002
M86.46 Chronic osteomyelitis with draining sinus (Lower leg)	0.000	0.998	0.002
J02 Acute pharyngitis	0.000	0.998	0.002
M85.67 Other cyst of bone (Ankle and foot)	0.002	0.998	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.998	0.002
S70-S79 Injuries to the hip and thigh	0.000	0.998	0.002
M85.19 Skeletal fluorosis (Site unspecified)	0.002	0.998	0.000
M85.18 Skeletal fluorosis (Other)	0.002	0.998	0.000
M85.17 Skeletal fluorosis (Ankle and foot)	0.002	0.998	0.000
M85.16 Skeletal fluorosis (Lower leg)	0.002	0.998	0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.002	0.998	0.000
M85.14 Skeletal fluorosis (Hand)	0.002	0.998	0.000
M85.13 Skeletal fluorosis (Forearm)	0.002	0.998	0.000
M85.12 Skeletal fluorosis (Upper arm)	0.002	0.998	0.000
M85.11 Skeletal fluorosis (Shoulder region)	0.002	0.998	0.000
M85.10 Skeletal fluorosis (Multiple sites)	0.002	0.998	0.000
M85.39 Osteitis condensans (Site unspecified)	0.002	0.998	0.000
M85.38 Osteitis condensans (Other)	0.002	0.998	0.000
M85.37 Osteitis condensans (Ankle and foot)	0.002	0.998	0.000
M85.36 Osteitis condensans (Lower leg)	0.002	0.998	0.000
M85.35 Osteitis condensans (Pelvic region and thigh)	0.002	0.998	0.000
M85.34 Osteitis condensans (Hand)	0.002	0.998	0.000
M85.33 Osteitis condensans (Forearm)	0.002	0.998	0.000
M85.32 Osteitis condensans (Upper arm)	0.002	0.998	0.000
M85.31 Osteitis condensans (Shoulder region)	0.002	0.998	0.000
M85.30 Osteitis condensans (Multiple sites)	0.002	0.998	0.000
M85.59 Aneurysmal bone cyst (Site unspecified)	0.002	0.998	0.000
M85.58 Aneurysmal bone cyst (Other)	0.002	0.998	0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.002	0.998	0.000
M85.56 Aneurysmal bone cyst (Lower leg)	0.002	0.998	0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.002	0.998	0.000
M85.54 Aneurysmal bone cyst (Hand)	0.002	0.998	0.000
M85.53 Aneurysmal bone cyst (Forearm)	0.002	0.998	0.000
M85.52 Aneurysmal bone cyst (Upper arm)	0.002	0.998	0.000
M85.51 Aneurysmal bone cyst (Shoulder region)	0.002	0.998	0.000
M85.50 Aneurysmal bone cyst (Multiple sites)	0.002	0.998	0.000
M82 Osteoporosis in diseases classified elsewhere	0.002	0.998	0.000
M85.68 Other cyst of bone (Other)	0.002	0.998	0.000
C77.2 Intra-abdominal lymph nodes	0.000	0.998	0.002
M24.51 Contracture of joint (Shoulder region)	0.002	0.998	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.002	0.998	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.002	0.998	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.002	0.998	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.002	0.998	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.002	0.998	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.002	0.998	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.002	0.998	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.002	0.998	0.000
S72.30 Fracture of shaft of femur (closed)	0.000	0.998	0.002
C77.8 Lymph nodes of multiple regions	0.000	0.998	0.002
F11.2 Dependence syndrome	0.000	0.998	0.002
S72.7 Multiple fractures of femur	0.000	0.998	0.002
M89.04 Algoneurodystrophy (Hand)	0.000	0.998	0.002
S72.80 Fractures of other parts of femur (closed)	0.000	0.998	0.002
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.998	0.002
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.000	0.998	0.002
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.002	0.998	0.000
S72.91 Fracture of femur, part unspecified (open)	0.000	0.998	0.002
M22.4 Chondromalacia patellae	0.000	0.998	0.002
M89.5 Osteolysis	0.000	0.998	0.002
M24.24 Disorder of ligament (Hand)	0.002	0.998	0.000
M89.08 Algoneurodystrophy (Other)	0.000	0.998	0.002
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.000	0.998	0.002
M89.02 Algoneurodystrophy (Upper arm)	0.000	0.998	0.002
M89.01 Algoneurodystrophy (Shoulder region)	0.000	0.998	0.002
M89.00 Algoneurodystrophy (Multiple sites)	0.000	0.998	0.002
S72.2 Subtrochanteric fracture	0.000	0.998	0.002
M24.52 Contracture of joint (Upper arm)	0.002	0.998	0.000
J02.0 Streptococcal pharyngitis	0.000	0.998	0.002
M85.29 Hyperostosis of skull-Site unspec	0.001	0.998	0.000
M85.28 Hyperostosis of skull-Other	0.001	0.998	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.001	0.998	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.001	0.998	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.001	0.998	0.000
M85.24 Hyperostosis of skull-Hand	0.001	0.998	0.000
M85.23 Hyperostosis of skull-Forearm	0.001	0.998	0.000
M85.22 Hyperostosis of skull-Upper arm	0.001	0.998	0.000
M85.21 Hyperostosis of skull-Shldr region	0.001	0.998	0.000
M86.17 Other acute osteomyelitis (Ankle and foot)	0.000	0.998	0.001
E85.4 Organ-limited amyloidosis	0.002	0.998	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.002	0.998	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.002	0.998	0.000
M24.59 Contracture of joint (Site unspecified)	0.002	0.998	0.000
M24.58 Contracture of joint (Other)	0.002	0.998	0.000
M24.53 Contracture of joint (Forearm)	0.002	0.998	0.000
M24.50 Contracture of joint (Multiple sites)	0.002	0.998	0.000
S72.81 Fractures of other parts of femur (open)	0.000	0.998	0.001
J94.8 Other specified pleural conditions	0.000	0.998	0.002
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.998	0.002
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.000	0.998	0.002
M83.9 Adult osteomalacia, unspecified	0.001	0.998	0.000
M83.5 Other drug-induced osteomalacia in adults	0.001	0.998	0.000
M83.4 Aluminum bone disease	0.001	0.998	0.000
M83.3 Adult osteomalacia due to malnutrition	0.001	0.998	0.000
M83.2 Adult osteomalacia due to malabsorption	0.001	0.998	0.000
M83.0 Puerperal osteomalacia	0.001	0.998	0.000
Z75.1 Person awaiting admission to adequate facility elsewhere	0.000	0.998	0.002
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.002	0.998	0.000
M83.1 Senile osteomalacia	0.001	0.998	0.000
Z00.5 Examination of potential donor of organ and tissue	0.002	0.998	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.000	0.998	0.001
H31.8 Other specified disorders of choroid	0.000	0.998	0.002
M82.8 Osteoporosis in other diseases classified elsewhere	0.001	0.998	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.001	0.998	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.001	0.998	0.000
M24 Other specific joint derangements	0.002	0.998	0.000
S78 Traumatic amputation of hip and thigh	0.000	0.998	0.002
S77 Crushing injury of hip and thigh	0.000	0.998	0.002
S75 Injury of blood vessels at hip and thigh level	0.000	0.998	0.002
S74 Injury of nerves at hip and thigh level	0.000	0.998	0.002
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.002	0.998	0.000
S02.60 Fracture of mandible (closed)	0.000	0.998	0.002
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.000	0.998	0.002
M89 Other disorders of bone	0.000	0.998	0.002
F41.2 Mixed anxiety and depressive disorder	0.000	0.998	0.002
T82.1 Mechanical complication of cardiac electronic device	0.000	0.998	0.002
M85.64 Other cyst of bone (Hand)	0.001	0.998	0.000
S72.71 Multiple fractures of femur (open)	0.000	0.998	0.001
S72.70 Multiple fractures of femur (closed)	0.000	0.998	0.001
G71.0 Muscular dystrophy	0.002	0.998	0.000
M87.2 Osteonecrosis due to previous trauma	0.000	0.998	0.002
W18.5 Trade and service area	0.000	0.998	0.002
M22 Disorders of patella	0.000	0.998	0.002
M07.30 Other psoriatic arthropathies (Multiple sites)	0.002	0.998	0.000
M83.8 Other adult osteomalacia	0.001	0.998	0.000
S20.3 Other superficial injuries of front wall of thorax	0.000	0.998	0.002
M24.56 Contracture of joint (Lower leg)	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations