TreeWAS – Variant ID: rs459482

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S81.8 Open wound of other parts of lower leg	0.046	0.954	0.000
S81 Open wound of lower leg	0.045	0.955	0.000
S81.0 Open wound of knee	0.044	0.956	0.000
S81.9 Open wound of lower leg, part unspecified	0.042	0.958	0.000
S81.7 Multiple open wounds of lower leg	0.032	0.968	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.019	0.981	0.000
E10.1 With ketoacidosis	0.013	0.987	0.000
E10 Insulin-dependent diabetes mellitus	0.012	0.988	0.000
E10.4 With neurological complications	0.011	0.989	0.000
E10.5 With peripheral circulatory complications	0.011	0.989	0.000
E10.6 With other specified complications	0.010	0.990	0.000
O80.9 Single spontaneous delivery, unspecified	0.009	0.991	0.000
E10.0 With coma	0.009	0.991	0.000
E10.2 With renal complications	0.009	0.991	0.000
E10.8 With unspecified complications	0.009	0.991	0.000
E10.3 With ophthalmic complications	0.009	0.991	0.000
E10.7 With multiple complications	0.009	0.991	0.000
A41.8 Other specified septicaemia	0.009	0.991	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.007	0.993	0.000
I42.2 Other hypertrophic cardiomyopathy	0.007	0.993	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.994	0.006
E10.9 Without complications	0.006	0.994	0.000
C53.9 Cervix uteri, unspecified	0.005	0.995	0.000
F52.2 Failure of genital response	0.005	0.995	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.005	0.995	0.000
I42 Cardiomyopathy	0.004	0.996	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.004	0.996	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.004	0.996	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.004	0.996	0.000
I82.8 Embolism and thrombosis of other specified veins	0.004	0.996	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.004	0.996	0.000
K58.0 Irritable bowel syndrome with diarrhoea	0.004	0.996	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.004	0.996	0.000
Y40.8 Other systemic antibiotics	0.000	0.996	0.004
I42.7 Cardiomyopathy due to drugs and other external agents	0.004	0.996	0.000
H81.0 Meniere's disease	0.004	0.996	0.000
Z98.1 Arthrodesis status	0.000	0.996	0.004
I42.5 Other restrictive cardiomyopathy	0.003	0.996	0.000
I42.4 Endocardial fibroelastosis	0.003	0.996	0.000
F50.0 Anorexia nervosa	0.003	0.997	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.997	0.003
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.003	0.997	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.003	0.997	0.000
M21.1 Varus deformity, not elsewhere classified	0.000	0.997	0.003
N85.9 Noninflammatory disorder of uterus, unspecified	0.000	0.997	0.003
S66.8 Injury of other muscles and tendons at wrist and hand level	0.003	0.997	0.000
F52.0 Lack or loss of sexual desire	0.003	0.997	0.000
C56 Malignant neoplasm of ovary	0.000	0.997	0.003
F50 Eating disorders	0.003	0.997	0.000
I35.0 Aortic (valve) stenosis	0.003	0.997	0.000
I42.8 Other cardiomyopathies	0.003	0.997	0.000
S92.41 Fracture of great toe (open)	0.000	0.997	0.003
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.003	0.997	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.003	0.997	0.000
S91.3 Open wound of other parts of foot	0.003	0.997	0.000
F50.9 Eating disorder, unspecified	0.003	0.997	0.000
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.003	0.997	0.000
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.003	0.997	0.000
F52.7 Excessive sexual drive	0.003	0.997	0.000
F52.6 Nonorganic dyspareunia	0.003	0.997	0.000
F52.5 Nonorganic vaginismus	0.003	0.997	0.000
F52.4 Premature ejaculation	0.003	0.997	0.000
F52.3 Orgasmic dysfunction	0.003	0.997	0.000
F52.1 Sexual aversion and lack of sexual enjoyment	0.003	0.997	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.000	0.997	0.003
N76.4 Abscess of vulva	0.003	0.997	0.000
M47.9 Spondylosis, unspecified	0.003	0.997	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.003	0.997	0.000
R25.2 Cramp and spasm	0.000	0.997	0.003
D47.2 Monoclonal gammopathy	0.003	0.997	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.000	0.997	0.003
M21.18 Varus deformity, not elsewhere classified (Other)	0.000	0.997	0.003
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.997	0.003
M21.14 Varus deformity, not elsewhere classified (Hand)	0.000	0.997	0.003
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.000	0.997	0.003
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.000	0.997	0.003
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.000	0.997	0.003
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.000	0.997	0.003
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.003	0.997	0.000
S92.4 Fracture of great toe	0.000	0.997	0.003
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.003	0.997	0.000
F50.8 Other eating disorders	0.002	0.997	0.000
F50.5 Vomiting associated with other psychological disturbances	0.002	0.997	0.000
F50.4 Overeating associated with other psychological disturbances	0.002	0.997	0.000
F50.3 Atypical bulimia nervosa	0.002	0.997	0.000
F50.1 Atypical anorexia nervosa	0.002	0.997	0.000
C53 Malignant neoplasm of cervix uteri	0.003	0.997	0.000
Q51.3 Bicornate uterus	0.003	0.997	0.000
I42.9 Cardiomyopathy, unspecified	0.002	0.998	0.000
I42.6 Alcoholic cardiomyopathy	0.002	0.998	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
S92.10 Fracture of talus (closed)	0.000	0.998	0.002
F55 Abuse of non-dependence-producing substances	0.002	0.998	0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.002	0.998	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.002	0.998	0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.002	0.998	0.000
S92.40 Fracture of great toe (closed)	0.000	0.998	0.002
M05.9 Seropositive rheumatoid arthritis, unspecified	0.002	0.998	0.000
X23.9 Unspecified place	0.000	0.998	0.002
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors	0.002	0.998	0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere	0.002	0.998	0.000
O80 Single spontaneous delivery	0.002	0.998	0.000
C62.9 Testis, unspecified	0.002	0.998	0.000
F50.2 Bulimia nervosa	0.002	0.998	0.000
J39.8 Other specified diseases of upper respiratory tract	0.002	0.998	0.000
F51 Nonorganic sleep disorders	0.002	0.998	0.000
M47.94 Spondylosis, unspecified (Thoracic region)	0.002	0.998	0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.002	0.998	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
F51.4 Sleep terrors [night terrors]	0.002	0.998	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.002	0.998	0.000
X23.0 Home	0.000	0.998	0.002
S92.1 Fracture of talus	0.000	0.998	0.002
H81 Disorders of vestibular function	0.002	0.998	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.002	0.998	0.000
R16.1 Splenomegaly, not elsewhere classified	0.002	0.998	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
S62.61 Fracture of other finger (open)	0.000	0.998	0.002
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.002	0.998	0.000
C53.8 Overlapping lesion of cervix uteri	0.002	0.998	0.000
C53.1 Exocervix	0.002	0.998	0.000
H54.7 Unspecified visual loss	0.000	0.998	0.002
H81.2 Vestibular neuronitis	0.002	0.998	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.002	0.998	0.000
D62 Acute posthaemorrhagic anaemia	0.002	0.998	0.000
S92 Fracture of foot, except ankle	0.000	0.998	0.002
C53.0 Endocervix	0.002	0.998	0.000
C79.6 Secondary malignant neoplasm of ovary	0.000	0.998	0.002
H81.9 Disorder of vestibular function, unspecified	0.002	0.998	0.000
Z03.4 Observation for suspected myocardial infarction	0.002	0.998	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.998	0.002
Q66.8 Other congenital deformities of feet	0.002	0.998	0.000
X23 Contact with hornets, wasps and bees	0.000	0.998	0.002
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.002	0.998	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.002	0.998	0.000
S92.51 Fracture of other toe (open)	0.000	0.998	0.002
O80.1 Spontaneous breech delivery	0.002	0.998	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.002	0.998	0.000
F51.9 Nonorganic sleep disorder, unspecified	0.002	0.998	0.000
F51.8 Other nonorganic sleep disorders	0.002	0.998	0.000
F51.2 Nonorganic disorder of the sleep-wake schedule	0.002	0.998	0.000
F51.1 Nonorganic hypersomnia	0.002	0.998	0.000
H80.9 Otosclerosis, unspecified	0.002	0.998	0.000
H81.8 Other disorders of vestibular function	0.002	0.998	0.000
F53.9 Puerperal mental disorder, unspecified	0.002	0.998	0.000
F53.8 Other mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.002	0.998	0.000
F53.1 Severe mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.002	0.998	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.002	0.998	0.000
S92.5 Fracture of other toe	0.000	0.998	0.002
F51.5 Nightmares	0.002	0.998	0.000
H81.3 Other peripheral vertigo	0.002	0.998	0.000
M75.2 Bicipital tendinitis	0.002	0.998	0.000
S92.11 Fracture of talus (open)	0.000	0.998	0.002
F53.0 Mild mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.002	0.998	0.000
H81.4 Vertigo of central origin	0.002	0.998	0.000
S91.0 Open wound of ankle	0.000	0.998	0.002
F51.3 Sleepwalking [somnambulism]	0.002	0.998	0.000
S92.0 Fracture of calcaneus	0.000	0.998	0.002
E10-E14 Diabetes mellitus	0.002	0.998	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.002	0.998	0.000
D47.1 Chronic myeloproliferative disease	0.002	0.998	0.000
E13 Other specified diabetes mellitus	0.002	0.998	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.002	0.998	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.002	0.998	0.000
K86.9 Disease of pancreas, unspecified	0.000	0.998	0.002
F51.0 Nonorganic insomnia	0.001	0.998	0.000
X23.8 Other specified place	0.000	0.998	0.002
X23.7 Farm	0.000	0.998	0.002
X23.6 Industrial and construction area	0.000	0.998	0.002
X23.5 Trade and service area	0.000	0.998	0.002
X23.4 Street and highway	0.000	0.998	0.002
X23.3 Sports and athletics area	0.000	0.998	0.002
X23.2 School, other institution and public administrative area	0.000	0.998	0.002
X23.1 Residential institution	0.000	0.998	0.002
M47.96 Spondylosis, unspecified (Lumbar region)	0.002	0.998	0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.002	0.998	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
E13.3 With ophthalmic complications	0.002	0.998	0.000
S92.7 Multiple fractures of foot	0.000	0.998	0.002
S91 Open wound of ankle and foot	0.000	0.998	0.001
C62.1 Descended testis	0.002	0.998	0.000
H35.7 Separation of retinal layers	0.002	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.000	0.998	0.002
S92.9 Fracture of foot, unspecified	0.000	0.998	0.001
E13.9 Without complications	0.002	0.998	0.000
S92.00 Fracture of calcaneus (closed)	0.000	0.998	0.002
O84.2 Multiple delivery, all by Caesarean section	0.001	0.998	0.000
E12 Malnutrition-related diabetes mellitus	0.001	0.998	0.000
O80-O84 Delivery	0.002	0.998	0.000
S92.01 Fracture of calcaneus (open)	0.000	0.998	0.001
D36.7 Other specified sites	0.000	0.998	0.002
M62.8 Other specified disorders of muscle	0.002	0.998	0.000
O81.3 Other and unspecified forceps delivery	0.001	0.998	0.000
O84 Multiple delivery	0.001	0.998	0.000
O81 Single delivery by forceps and vacuum extractor	0.002	0.998	0.000
S31.4 Open wound of vagina and vulva	0.002	0.998	0.000
D53.9 Nutritional anaemia, unspecified	0.002	0.998	0.000
E13.8 With unspecified complications	0.001	0.998	0.000
E13.7 With multiple complications	0.001	0.998	0.000
E13.6 With other specified complications	0.001	0.998	0.000
E13.5 With peripheral circulatory complications	0.001	0.998	0.000
E13.4 With neurological complications	0.001	0.998	0.000
E13.2 With renal complications	0.001	0.998	0.000
E13.1 With ketoacidosis	0.001	0.998	0.000
E13.0 With coma	0.001	0.998	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.002	0.998	0.000
S90.3 Contusion of other and unspecified parts of foot	0.000	0.998	0.001
C62 Malignant neoplasm of testis	0.002	0.998	0.000
C82.3 Follicular lymphoma grade IIIa	0.000	0.998	0.001
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.001	0.998	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.998	0.001
R73.0 Abnormal glucose tolerance test	0.002	0.998	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.001	0.998	0.000
M35.0 Sicca syndrome [Sjogren]	0.002	0.998	0.000
N89.8 Other specified noninflammatory disorders of vagina	0.000	0.998	0.002
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.001	0.998	0.000
S91.1 Open wound of toe(s) without damage to nail	0.000	0.998	0.001
T63.4 Venom of other arthropods	0.000	0.998	0.001
C82.2 Large cell, follicular	0.000	0.999	0.001
O82.9 Delivery by Caesarean section, unspecified	0.001	0.999	0.000
S92.3 Fracture of metatarsal bone	0.000	0.999	0.001
S92.71 Multiple fractures of foot (open)	0.000	0.999	0.001
D63.8 Anaemia in other chronic diseases classified elsewhere	0.001	0.999	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.001	0.999	0.000
S91.7 Multiple open wounds of ankle and foot	0.000	0.999	0.001
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.000	0.999	0.001
M62.89 Other specified disorders of muscle (Site unspecified)	0.001	0.999	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.001	0.999	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.000	0.999	0.001
S92.50 Fracture of other toe (closed)	0.000	0.999	0.001
O81.0 Low forceps delivery	0.001	0.999	0.000
S91.2 Open wound of toe(s) with damage to nail	0.000	0.999	0.001
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.001	0.999	0.000
H80 Otosclerosis	0.001	0.999	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.001	0.999	0.000
S92.91 Fracture of foot, unspecified (open)	0.000	0.999	0.001
C77.0 Lymph nodes of head, face and neck	0.001	0.999	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
C73 Malignant neoplasm of thyroid gland	0.000	0.999	0.001
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.999	0.001
E12.9 Without complications	0.001	0.999	0.000
E12.8 With unspecified complications	0.001	0.999	0.000
E12.7 With multiple complications	0.001	0.999	0.000
E12.6 With other specified complications	0.001	0.999	0.000
E12.5 With peripheral circulatory complications	0.001	0.999	0.000
E12.4 With neurological complications	0.001	0.999	0.000
E12.3 With ophthalmic complications	0.001	0.999	0.000
E12.2 With renal complications	0.001	0.999	0.000
E12.1 With ketoacidosis	0.001	0.999	0.000
E12.0 With coma	0.001	0.999	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.001	0.999	0.000
O83 Other assisted single delivery	0.001	0.999	0.000
C09.9 Tonsil, unspecified	0.001	0.999	0.000
O81.5 Delivery by combination of forceps and vacuum extractor	0.001	0.999	0.000
O81.2 Mid-cavity forceps with rotation	0.001	0.999	0.000
O81.1 Mid-cavity forceps delivery	0.001	0.999	0.000
O84.9 Multiple delivery, unspecified	0.001	0.999	0.000
O84.8 Other multiple delivery	0.001	0.999	0.000
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.001	0.999	0.000
O84.0 Multiple delivery, all spontaneous	0.001	0.999	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.000	0.999	0.001
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.999	0.001
M05 Seropositive rheumatoid arthritis	0.001	0.999	0.000
C62.0 Undescended testis	0.001	0.999	0.000
C82.4 Follicular lymphoma grade IIIb	0.000	0.999	0.001
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)	0.001	0.999	0.000
G24.8 Other dystonia	0.000	0.999	0.001
O80.8 Other single spontaneous delivery	0.001	0.999	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.000	0.999	0.001
O82 Single delivery by Caesarean section	0.001	0.999	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.001	0.999	0.000
K42.0 Umbilical hernia with obstruction, without gangrene	0.000	0.999	0.001
O81.4 Vacuum extractor delivery	0.001	0.999	0.000
S13.4 Sprain and strain of cervical spine	0.001	0.999	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.000	0.999	0.001
M13.86 Other specified arthritis (Lower leg)	0.001	0.999	0.000
M62.84 Other specified disorders of muscle (Hand)	0.001	0.999	0.000
S92.31 Fracture of metatarsal bone (open)	0.000	0.999	0.001
S92.70 Multiple fractures of foot (closed)	0.000	0.999	0.001
S92.90 Fracture of foot, unspecified (closed)	0.001	0.999	0.001
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.001	0.999	0.000
D47.4 Osteomyelofibrosis	0.001	0.999	0.000
M05.0 Felty's syndrome	0.001	0.999	0.000
S14.3 Injury of brachial plexus	0.001	0.999	0.000
M62.88 Other specified disorders of muscle (Other)	0.001	0.999	0.000
G24.9 Dystonia, unspecified	0.000	0.999	0.001
H80.8 Other otosclerosis	0.001	0.999	0.000
H80.2 Cochlear otosclerosis	0.001	0.999	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.001	0.999	0.000
J38.2 Nodules of vocal cords	0.001	0.999	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.001	0.999	0.000
Q65.8 Other congenital deformities of hip	0.001	0.999	0.000
S90-S99 Injuries to the ankle and foot	0.000	0.999	0.001
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.999	0.001
O83.9 Assisted single delivery, unspecified	0.001	0.999	0.000
O83.8 Other specified assisted single delivery	0.001	0.999	0.000
O83.4 Destructive operation for delivery	0.001	0.999	0.000
O83.3 Delivery of viable foetus in abdominal pregnancy	0.001	0.999	0.000
O83.2 Other manipulation-assisted delivery	0.001	0.999	0.000
O83.1 Other assisted breech delivery	0.001	0.999	0.000
O83.0 Breech extraction	0.001	0.999	0.000
S13.1 Dislocation of cervical vertebra	0.001	0.999	0.000
X59.2 School, other institution and public administrative area	0.000	0.999	0.001
Y60.0 During surgical operation	0.001	0.999	0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.001	0.999	0.000
M05.09 Felty's syndrome (Site unspecified)	0.001	0.999	0.000
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)	0.001	0.999	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.999	0.001
C82.6 Cutaneous follicle centre lymphoma	0.000	0.999	0.001
C82.5 Diffuse follicle centre lymphoma	0.000	0.999	0.001
M05.8 Other seropositive rheumatoid arthritis	0.001	0.999	0.000
S99.8 Other specified injuries of ankle and foot	0.000	0.999	0.001
K09.8 Other cysts of oral region, not elsewhere classified	0.000	0.999	0.001
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.001	0.999	0.000
M05.2 Rheumatoid vasculitis	0.001	0.999	0.000
M05.1 Rheumatoid lung disease	0.001	0.999	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.000	0.999	0.001
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.999	0.001
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)	0.001	0.999	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.001	0.999	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.001	0.999	0.000
O82.8 Other single delivery by Caesarean section	0.001	0.999	0.000
O82.2 Delivery by Caesarean hysterectomy	0.001	0.999	0.000
Y45.1 Salicylates	0.000	0.999	0.001
M13.89 Other specified arthritis (Site unspecified)	0.001	0.999	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.001	0.999	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.000	0.999	0.001
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.000	0.999	0.001
Q51 Congenital malformations of uterus and cervix	0.001	0.999	0.000
S99 Other and unspecified injuries of ankle and foot	0.000	0.999	0.001
M05.08 Felty's syndrome (Other)	0.001	0.999	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.001	0.999	0.000
M05.06 Felty's syndrome (Lower leg)	0.001	0.999	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.001	0.999	0.000
M05.04 Felty's syndrome (Hand)	0.001	0.999	0.000
M05.03 Felty's syndrome (Forearm)	0.001	0.999	0.000
M05.02 Felty's syndrome (Upper arm)	0.001	0.999	0.000
M05.01 Felty's syndrome (Shoulder region)	0.001	0.999	0.000
M05.00 Felty's syndrome (Multiple sites)	0.001	0.999	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.001	0.999	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.001	0.999	0.000
S98 Traumatic amputation of ankle and foot	0.000	0.999	0.001
S95 Injury of blood vessels at ankle and foot level	0.000	0.999	0.001
S94 Injury of nerves at ankle and foot level	0.000	0.999	0.001
M79.09 Rheumatism, unspecified (Site unspecified)	0.001	0.999	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.001	0.999	0.000
K59.1 Functional diarrhoea	0.001	0.999	0.000
S12.9 Fracture of neck, part unspecified	0.001	0.999	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.001	0.999	0.000
M05.18 Rheumatoid lung disease (Other)	0.001	0.999	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.001	0.999	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.001	0.999	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.001	0.999	0.000
M05.14 Rheumatoid lung disease (Hand)	0.001	0.999	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.001	0.999	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.001	0.999	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.001	0.999	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.001	0.999	0.000
M05.28 Rheumatoid vasculitis (Other)	0.001	0.999	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.001	0.999	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.001	0.999	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.001	0.999	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.001	0.999	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.001	0.999	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.001	0.999	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.001	0.999	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.001	0.999	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.001	0.999	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.001	0.999	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.001	0.999	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.001	0.999	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.001	0.999	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.001	0.999	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.001	0.999	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.001	0.999	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.001	0.999	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.001	0.999	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.001	0.999	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.001	0.999	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.001	0.999	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.001	0.999	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.001	0.999	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.001	0.999	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.001	0.999	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.001	0.999	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.001	0.999	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.001	0.999	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.001	0.999	0.000
M13.80 Other specified arthritis (Multiple sites)	0.001	0.999	0.000
L53.8 Other specified erythematous conditions	0.001	0.999	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.001	0.999	0.000
O82.0 Delivery by elective Caesarean section	0.001	0.999	0.000
R70.0 Elevated erythrocyte sedimentation rate	0.000	0.999	0.001
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.001	0.999	0.000
Y60.4 During endoscopic examination	0.001	0.999	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.001	0.999	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.001	0.999	0.000
K56.7 Ileus, unspecified	0.001	0.999	0.000
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.001	0.999	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.000	0.999	0.001
T59.8 Other specified gases, fumes and vapours	0.000	0.999	0.001
Y54.4 Loop [high-ceiling] diuretics	0.000	0.999	0.001
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.001	0.999	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.001	0.999	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.001	0.999	0.000
Q51.6 Embryonic cyst of cervix	0.001	0.999	0.000
Q51.5 Agenesis and aplasia of cervix	0.001	0.999	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.001	0.999	0.000
Q51.0 Agenesis and aplasia of uterus	0.001	0.999	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.000	0.999	0.001
S94.8 Injury of other nerves at ankle and foot level	0.000	0.999	0.001
S94.7 Injury of multiple nerves at ankle and foot level	0.000	0.999	0.001
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.000	0.999	0.001
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.000	0.999	0.001
S94.1 Injury of medial plantar nerve	0.000	0.999	0.001
S94.0 Injury of lateral plantar nerve	0.000	0.999	0.001
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.000	0.999	0.001
S95.8 Injury of other blood vessels at ankle and foot level	0.000	0.999	0.001
S95.7 Injury of multiple blood vessels at ankle and foot level	0.000	0.999	0.001
S95.2 Injury of dorsal vein of foot	0.000	0.999	0.001
S95.1 Injury of plantar artery of foot	0.000	0.999	0.001
S95.0 Injury of dorsal artery of foot	0.000	0.999	0.001
S96.8 Injury of other muscles and tendons at ankle and foot level	0.000	0.999	0.001
S98.4 Traumatic amputation of foot, level unspecified	0.000	0.999	0.001
S98.3 Traumatic amputation of other parts of foot	0.000	0.999	0.001
S98.2 Traumatic amputation of two or more toes	0.000	0.999	0.001
S98.1 Traumatic amputation of one toe	0.000	0.999	0.001
S98.0 Traumatic amputation of foot at ankle level	0.000	0.999	0.001
S99.7 Multiple injuries of ankle and foot	0.000	0.999	0.001
M40.24 Other and unspecified kyphosis (Thoracic region)	0.000	0.999	0.001
S12.91 Fracture of neck, part unspecified (open)	0.001	0.999	0.000
S12.1 Fracture of second cervical vertebra	0.001	0.999	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.001	0.999	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.000	0.999	0.001
S97 Crushing injury of ankle and foot	0.000	0.999	0.001
S90 Superficial injury of ankle and foot	0.000	0.999	0.001
M49.59 Collapsed vertebra in diseases classified elsewhere (Site unspecified)	0.001	0.999	0.000
M49.58 Collapsed vertebra in diseases classified elsewhere (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M49.57 Collapsed vertebra in diseases classified elsewhere (Lumbosacral region)	0.001	0.999	0.000
M49.55 Collapsed vertebra in diseases classified elsewhere (Thoracolumbar region)	0.001	0.999	0.000
M49.53 Collapsed vertebra in diseases classified elsewhere (Cervicothoracic region)	0.001	0.999	0.000
M49.52 Collapsed vertebra in diseases classified elsewhere (Cervical region)	0.001	0.999	0.000
M49.51 Collapsed vertebra in diseases classified elsewhere (Occipito-atlanto-axial region)	0.001	0.999	0.000
C18.3 Hepatic flexure	0.001	0.999	0.000
E14.0 With coma	0.001	0.999	0.000
Q51.2 Other doubling of uterus	0.001	0.999	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.001	0.999	0.000
S13.5 Sprain and strain of thyroid region	0.001	0.999	0.000
S13.3 Multiple dislocations of neck	0.001	0.999	0.000
S13.2 Dislocation of other and unspecified parts of neck	0.001	0.999	0.000
S13.0 Traumatic rupture of cervical intervertebral disk	0.001	0.999	0.000
Y53.4 Other laxatives	0.000	0.999	0.001
Z52.4 Kidney donor	0.000	0.999	0.001
Z52.0 Blood donor	0.000	0.999	0.001
M79.54 Residual foreign body in soft tissue (Hand)	0.001	0.999	0.000
G06.1 Intraspinal abscess and granuloma	0.001	0.999	0.000
R94.6 Abnormal results of thyroid function studies	0.000	0.999	0.001
S86 Injury of muscle and tendon at lower leg level	0.001	0.999	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.000	0.999	0.001
H80-H83 Diseases of inner ear	0.001	0.999	0.000
M62.96 Disorder of muscle, unspecified (Lower leg)	0.001	0.999	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.999	0.001
S12.11 Fracture of second cervical vertebra (open)	0.001	0.999	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.999	0.001
D10.3 Other and unspecified parts of mouth	0.000	0.999	0.001
D38.1 Trachea, bronchus and lung	0.000	0.999	0.001
M13.8 Other specified arthritis	0.001	0.999	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.000	0.999	0.001
S90.2 Contusion of toe(s) with damage to nail	0.000	0.999	0.001
S93.3 Dislocation of other and unspecified parts of foot	0.000	0.999	0.001
S93.0 Dislocation of ankle joint	0.000	0.999	0.001
S97.1 Crushing injury of toe(s)	0.000	0.999	0.001
S97.0 Crushing injury of ankle	0.000	0.999	0.001
M13.84 Other specified arthritis (Hand)	0.001	0.999	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.001	0.999	0.000
E89.0 Postprocedural hypothyroidism	0.000	0.999	0.001
K02.8 Other dental caries	0.001	0.999	0.000
K14.0 Glossitis	0.001	0.999	0.000
K56.6 Other and unspecified intestinal obstruction	0.001	0.999	0.000
S86.0 Injury of Achilles tendon	0.001	0.999	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.001	0.999	0.000
X59.4 Street and highway	0.000	0.999	0.001
M13.88 Other specified arthritis (Other)	0.001	0.999	0.000
M13.87 Other specified arthritis (Ankle and foot)	0.001	0.999	0.000
M13.85 Other specified arthritis (Pelvic region and thigh)	0.001	0.999	0.000
M13.83 Other specified arthritis (Forearm)	0.001	0.999	0.000
M13.82 Other specified arthritis (Upper arm)	0.001	0.999	0.000
M13.81 Other specified arthritis (Shoulder region)	0.001	0.999	0.000
S12.00 Fracture of first cervical vertebra (closed)	0.001	0.999	0.000
E14.2 Withrenal complications	0.001	0.999	0.000
F30.9 Manic episode, unspecified	0.000	0.999	0.001
N05.1 Focal and segmental glomerular lesions	0.001	0.999	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.001	0.999	0.000
Q51.4 Unicornate uterus	0.001	0.999	0.000
S93.4 Sprain and strain of ankle	0.000	0.999	0.001
S93.6 Sprain and strain of other and unspecified parts of foot	0.000	0.999	0.001
S93.5 Sprain and strain of toe(s)	0.000	0.999	0.001
S93.2 Rupture of ligaments at ankle and foot level	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations