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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4618569
log Bayes Factor = 74.7952
Chromosome 6   position 30,855,251  (GRCh37) Explore rs4618569 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.001 0.999
E10.9 Without complications
0.000 0.001 0.999
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.004 0.996
L40.0 Psoriasis vulgaris
0.996 0.004 0.000
E10-E14 Diabetes mellitus
0.000 0.015 0.985
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.015 0.985
E10.4 With neurological complications
0.000 0.034 0.966
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.052 0.948
M07.39 Other psoriatic arthropathies (Site unspecified)
0.931 0.069 0.000
M07.3 Other psoriatic arthropathies
0.930 0.070 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.926 0.074 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.079 0.921
E10.3 With ophthalmic complications
0.000 0.091 0.909
E16.2 Hypoglycaemia, unspecified
0.000 0.097 0.903
E10.1 With ketoacidosis
0.000 0.098 0.902
E10.5 With peripheral circulatory complications
0.000 0.102 0.898
L40.8 Other psoriasis
0.890 0.110 0.000
E07 Other disorders of thyroid
0.000 0.115 0.885
L40.1 Generalised pustular psoriasis
0.854 0.146 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.163 0.837
E10.6 With other specified complications
0.000 0.165 0.835
M07.34 Other psoriatic arthropathies (Hand)
0.819 0.181 0.000
E10.2 With renal complications
0.000 0.184 0.816
E10.0 With coma
0.000 0.188 0.812
E06 Thyroiditis
0.000 0.201 0.799
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.205 0.795
M07.36 Other psoriatic arthropathies (Lower leg)
0.793 0.207 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.773 0.227 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.245 0.755
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.266 0.734
E50-E64 Other nutritional deficiencies
0.000 0.270 0.730
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.277 0.723
E05.8 Other thyrotoxicosis
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.294 0.706
E15 Nondiabetic hypoglycaemic coma
0.000 0.320 0.679
M07.38 Other psoriatic arthropathies (Other)
0.667 0.333 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.667 0.333 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.667 0.333 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.667 0.333 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.667 0.333 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.339 0.661
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.339 0.661
E16.4 Abnormal secretion of gastrin
0.000 0.339 0.661
E16.3 Increased secretion of glucagon
0.000 0.339 0.661
E06.3 Autoimmune thyroiditis
0.000 0.350 0.650
E07.1 Dyshormogenetic goitre
0.000 0.366 0.634
E07.0 Hypersecretion of calcitonin
0.000 0.366 0.634
E03.8 Other specified hypothyroidism
0.000 0.395 0.605
E06.9 Thyroiditis, unspecified
0.000 0.419 0.580
E55 Vitamin D deficiency
0.000 0.421 0.579
E06.5 Other chronic thyroiditis
0.000 0.427 0.573
E06.4 Drug-induced thyroiditis
0.000 0.427 0.573
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.427 0.573
E06.1 Subacute thyroiditis
0.000 0.427 0.573
E06.0 Acute thyroiditis
0.000 0.427 0.573
E16.1 Other hypoglycaemia
0.000 0.433 0.567
E13 Other specified diabetes mellitus
0.000 0.437 0.562
E10.8 With unspecified complications
0.000 0.447 0.552
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.476 0.524
E63 Other nutritional deficiencies
0.000 0.476 0.524
E56 Other vitamin deficiencies
0.000 0.476 0.524
E51 Thiamine deficiency
0.000 0.476 0.524
E50 Vitamin A deficiency
0.000 0.476 0.524
E60 Dietary zinc deficiency
0.000 0.476 0.524
E59 Dietary selenium deficiency
0.000 0.476 0.524
E58 Dietary calcium deficiency
0.000 0.476 0.524
E54 Ascorbic acid deficiency
0.000 0.476 0.524
E52 Niacin deficiency [pellagra]
0.000 0.476 0.524
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
K90 Intestinal malabsorption
0.000 0.489 0.511
E61 Deficiency of other nutrient elements
0.000 0.491 0.508
E65-E68 Obesity and other hyperalimentation
0.000 0.493 0.506
E12.9 Without complications
0.000 0.493 0.506
E12.8 With unspecified complications
0.000 0.493 0.506
E12.7 With multiple complications
0.000 0.493 0.506
E12.6 With other specified complications
0.000 0.493 0.506
E12.5 With peripheral circulatory complications
0.000 0.493 0.506
E12.4 With neurological complications
0.000 0.493 0.506
E12.3 With ophthalmic complications
0.000 0.493 0.506
E12.2 With renal complications
0.000 0.493 0.506
E12.1 With ketoacidosis
0.000 0.493 0.506
E12.0 With coma
0.000 0.493 0.506
E53 Deficiency of other B group vitamins
0.000 0.502 0.498
E40-E46 Malnutrition
0.001 0.509 0.490
E55.9 Vitamin D deficiency, unspecified
0.000 0.529 0.471
E14 Unspecified diabetes mellitus
0.000 0.548 0.452
E07.8 Other specified disorders of thyroid
0.000 0.551 0.448
E04 Other non-toxic goitre
0.000 0.566 0.434
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.571 0.429
E55.0 Rickets, active
0.000 0.585 0.415
M07 Psoriatic and enteropathic arthropathies
0.406 0.593 0.000
E13.8 With unspecified complications
0.000 0.596 0.403
E13.7 With multiple complications
0.000 0.596 0.403
E13.6 With other specified complications
0.000 0.596 0.403
E13.5 With peripheral circulatory complications
0.000 0.596 0.403
E13.4 With neurological complications
0.000 0.596 0.403
E13.3 With ophthalmic complications
0.000 0.596 0.403
E13.2 With renal complications
0.000 0.596 0.403
E13.1 With ketoacidosis
0.000 0.596 0.403
E13.0 With coma
0.000 0.596 0.403
K90.9 Intestinal malabsorption, unspecified
0.000 0.606 0.394
E14.3 With ophthalmic complications
0.000 0.607 0.393
E53.9 Vitamin B deficiency, unspecified
0.000 0.620 0.380
E50.9 Vitamin A deficiency, unspecified
0.000 0.624 0.375
E50.8 Other manifestations of vitamin A deficiency
0.000 0.624 0.375
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.624 0.375
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.624 0.375
E50.5 Vitamin A deficiency with night blindness
0.000 0.624 0.375
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.624 0.375
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.624 0.375
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.624 0.375
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.624 0.375
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.624 0.375
E51.9 Thiamine deficiency, unspecified
0.000 0.624 0.375
E51.8 Other manifestations of thiamine deficiency
0.000 0.624 0.375
E51.2 Wernicke's encephalopathy
0.000 0.624 0.375
E51.1 Beriberi
0.000 0.624 0.375
E56.9 Vitamin deficiency, unspecified
0.000 0.624 0.375
E56.8 Deficiency of other vitamins
0.000 0.624 0.375
E56.1 Deficiency of vitamin K
0.000 0.624 0.375
E56.0 Deficiency of vitamin E
0.000 0.624 0.375
E63.9 Nutritional deficiency, unspecified
0.000 0.624 0.375
E63.8 Other specified nutritional deficiencies
0.000 0.624 0.375
E63.1 Imbalance of constituents of food intake
0.000 0.624 0.375
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.624 0.375
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.624 0.375
E64.8 Sequelae of other nutritional deficiencies
0.000 0.624 0.375
E64.3 Sequelae of rickets
0.000 0.624 0.375
E64.2 Sequelae of vitamin C deficiency
0.000 0.624 0.375
E64.1 Sequelae of vitamin A deficiency
0.000 0.624 0.375
E64.0 Sequelae of protein-energy malnutrition
0.000 0.624 0.375
E61.2 Magnesium deficiency
0.000 0.628 0.372
K90.3 Pancreatic steatorrhoea
0.000 0.634 0.366
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.634 0.366
K90.1 Tropical sprue
0.000 0.634 0.366
E61.9 Deficiency of nutrient element, unspecified
0.000 0.635 0.365
E61.8 Deficiency of other specified nutrient elements
0.000 0.635 0.365
E61.7 Deficiency of multiple nutrient elements
0.000 0.635 0.365
E61.6 Vanadium deficiency
0.000 0.635 0.365
E61.5 Molybdenum deficiency
0.000 0.635 0.365
E61.4 Chromium deficiency
0.000 0.635 0.365
E61.3 Manganese deficiency
0.000 0.635 0.365
E61.0 Copper deficiency
0.000 0.635 0.365
E67 Other hyperalimentation
0.000 0.637 0.363
E68 Sequelae of hyperalimentation
0.000 0.637 0.363
E53.1 Pyridoxine deficiency
0.000 0.643 0.357
E53.0 Riboflavin deficiency
0.000 0.643 0.357
E44 Protein-energy malnutrition of moderate and mild degree
0.001 0.648 0.352
E45 Retarded development following protein-energy malnutrition
0.001 0.648 0.352
E43 Unspecified severe protein-energy malnutrition
0.001 0.648 0.352
E42 Marasmic kwashiorkor
0.001 0.648 0.352
E41 Nutritional marasmus
0.001 0.648 0.352
E40 Kwashiorkor
0.001 0.648 0.352
E61.1 Iron deficiency
0.000 0.659 0.340
E04.9 Non-toxic goitre, unspecified
0.000 0.664 0.336
E14.7 With multiple complications
0.000 0.676 0.324
E14.6 With other specified complications
0.000 0.676 0.324
E14.2 Withrenal complications
0.000 0.676 0.324
E14.0 With coma
0.000 0.676 0.324
E14.1 With ketoacidosis
0.000 0.682 0.318
E04.8 Other specified non-toxic goitre
0.000 0.688 0.311
E14.8 With unspecified complications
0.000 0.690 0.310
E53.8 Deficiency of other specified B group vitamins
0.000 0.700 0.300
E65 Localised adiposity
0.000 0.704 0.296
E14.5 With peripheral circulatory complications
0.000 0.708 0.292
M07.6 Other enteropathic arthropathies
0.291 0.708 0.000
M07.5 Arthropathy in ulcerative colitis
0.291 0.708 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.291 0.708 0.000
M07.2 Psoriatic spondylitis
0.291 0.708 0.000
M07.1 Arthritis mutilans
0.291 0.708 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.291 0.708 0.000
E66 Obesity
0.000 0.727 0.273
E04.0 Non-toxic diffuse goitre
0.000 0.734 0.266
E14.4 With neurological complications
0.000 0.738 0.262
E67.8 Other specified hyperalimentation
0.000 0.739 0.260
E67.3 Hypervitaminosis D
0.000 0.739 0.260
E67.2 Megavitamin-B6 syndrome
0.000 0.739 0.260
E67.1 Hypercarotenaemia
0.000 0.739 0.260
E67.0 Hypervitaminosis A
0.000 0.739 0.260
K90.8 Other intestinal malabsorption
0.000 0.740 0.260
E13.9 Without complications
0.000 0.740 0.259
E44.1 Mild protein-energy malnutrition
0.001 0.747 0.252
E44.0 Moderate protein-energy malnutrition
0.001 0.747 0.252
E66.8 Other obesity
0.000 0.750 0.250
E04.2 Non-toxic multinodular goitre
0.000 0.755 0.245
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.000 0.765 0.235
L40-L45 Papulosquamous disorders
0.225 0.774 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.790 0.210
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.209 0.791 0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.209 0.791 0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.209 0.791 0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.209 0.791 0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.209 0.791 0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.209 0.791 0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.209 0.791 0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.209 0.791 0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.209 0.791 0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.209 0.791 0.000
M07.19 Arthritis mutilans (Site unspecified)
0.209 0.791 0.000
M07.18 Arthritis mutilans (Other)
0.209 0.791 0.000
M07.17 Arthritis mutilans (Ankle and foot)
0.209 0.791 0.000
M07.16 Arthritis mutilans (Lower leg)
0.209 0.791 0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.209 0.791 0.000
M07.14 Arthritis mutilans (Hand)
0.209 0.791 0.000
M07.13 Arthritis mutilans (Forearm)
0.209 0.791 0.000
M07.12 Arthritis mutilans (Upper arm)
0.209 0.791 0.000
M07.11 Arthritis mutilans (Shoulder region)
0.209 0.791 0.000
M07.10 Arthritis mutilans (Multiple sites)
0.209 0.791 0.000
M07.29 Psoriatic spondylitis (Site unspecified)
0.209 0.791 0.000
M07.28 Psoriatic spondylitis (Other)
0.209 0.791 0.000
M07.27 Psoriatic spondylitis (Ankle and foot)
0.209 0.791 0.000
M07.26 Psoriatic spondylitis (Lower leg)
0.209 0.791 0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.209 0.791 0.000
M07.24 Psoriatic spondylitis (Hand)
0.209 0.791 0.000
M07.23 Psoriatic spondylitis (Forearm)
0.209 0.791 0.000
M07.22 Psoriatic spondylitis (Upper arm)
0.209 0.791 0.000
M07.21 Psoriatic spondylitis (Shoulder region)
0.209 0.791 0.000
M07.20 Psoriatic spondylitis (Multiple sites)
0.209 0.791 0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.209 0.791 0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.209 0.791 0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.209 0.791 0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.209 0.791 0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.209 0.791 0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.209 0.791 0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.209 0.791 0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.209 0.791 0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.209 0.791 0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.209 0.791 0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.209 0.791 0.000
M07.58 Arthropathy in ulcerative colitis (Other)
0.209 0.791 0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.209 0.791 0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.209 0.791 0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.209 0.791 0.000
M07.54 Arthropathy in ulcerative colitis (Hand)
0.209 0.791 0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.209 0.791 0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.209 0.791 0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.209 0.791 0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.209 0.791 0.000
M07.69 Other enteropathic arthropathies (Site unspecified)
0.209 0.791 0.000
M07.68 Other enteropathic arthropathies (Other)
0.209 0.791 0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.209 0.791 0.000
M07.66 Other enteropathic arthropathies (Lower leg)
0.209 0.791 0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.209 0.791 0.000
M07.64 Other enteropathic arthropathies (Hand)
0.209 0.791 0.000
M07.63 Other enteropathic arthropathies (Forearm)
0.209 0.791 0.000
M07.62 Other enteropathic arthropathies (Upper arm)
0.209 0.791 0.000
M07.61 Other enteropathic arthropathies (Shoulder region)
0.209 0.791 0.000
M07.60 Other enteropathic arthropathies (Multiple sites)
0.209 0.791 0.000
E66.1 Drug-induced obesity
0.000 0.804 0.196
E04.1 Non-toxic single thyroid nodule
0.000 0.805 0.194
E27 Other disorders of adrenal gland
0.000 0.812 0.188
E27.1 Primary adrenocortical insufficiency
0.000 0.814 0.186
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.830 0.170
L44 Other papulosquamous disorders
0.162 0.838 0.000
L41 Parapsoriasis
0.162 0.838 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.162 0.838 0.000
L42 Pityriasis rosea
0.156 0.843 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.849 0.150
E32 Diseases of thymus
0.000 0.849 0.150
E31 Polyglandular dysfunction
0.000 0.849 0.150
E30 Disorders of puberty, not elsewhere classified
0.000 0.849 0.150
E25 Adrenogenital disorders
0.000 0.849 0.150
E29 Testicular dysfunction
0.000 0.857 0.143
E34 Other endocrine disorders
0.000 0.858 0.142
E27.8 Other specified disorders of adrenal gland
0.000 0.859 0.141
E20 Hypoparathyroidism
0.000 0.859 0.141
E46 Unspecified protein-energy malnutrition
0.002 0.862 0.136
E66.0 Obesity due to excess calories
0.000 0.862 0.137
E27.5 Adrenomedullary hyperfunction
0.000 0.865 0.135
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.865 0.135
E27.0 Other adrenocortical overactivity
0.000 0.865 0.135
E22 Hyperfunction of pituitary gland
0.000 0.869 0.131
E26 Hyperaldosteronism
0.000 0.870 0.130
E24 Cushing's syndrome
0.000 0.871 0.129
E27.2 Addisonian crisis
0.000 0.875 0.125
E28 Ovarian dysfunction
0.000 0.876 0.124
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.122 0.878 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.119 0.881 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.118 0.882 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.117 0.883 0.000
L41.9 Parapsoriasis, unspecified
0.116 0.884 0.000
L41.8 Other parapsoriasis
0.116 0.884 0.000
L41.5 Retiform parapsoriasis
0.116 0.884 0.000
L41.4 Large plaque parapsoriasis
0.116 0.884 0.000
L41.3 Small plaque parapsoriasis
0.116 0.884 0.000
L41.2 Lymphomatoid papulosis
0.116 0.884 0.000
L41.1 Pityriasis lichenoides chronica
0.116 0.884 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.116 0.884 0.000
L44.9 Papulosquamous disorder, unspecified
0.116 0.884 0.000
L44.8 Other specified papulosquamous disorders
0.116 0.884 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.116 0.884 0.000
L44.3 Lichen ruber moniliformis
0.116 0.884 0.000
L44.2 Lichen striatus
0.116 0.884 0.000
L44.1 Lichen nitidus
0.116 0.884 0.000
L44.0 Pityriasis rubra pilaris
0.116 0.884 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.112 0.888 0.000
T43.2 Other and unspecified antidepressants
0.110 0.890 0.000
E25.9 Adrenogenital disorder, unspecified
0.000 0.892 0.108
E25.8 Other adrenogenital disorders
0.000 0.892 0.108
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.892 0.108
E30.9 Disorder of puberty, unspecified
0.000 0.892 0.108
E30.8 Other disorders of puberty
0.000 0.892 0.108
E30.1 Precocious puberty
0.000 0.892 0.108
E30.0 Delayed puberty
0.000 0.892 0.108
E31.9 Polyglandular dysfunction, unspecified
0.000 0.892 0.108
E31.8 Other polyglandular dysfunction
0.000 0.892 0.108
E31.1 Polyglandular hyperfunction
0.000 0.892 0.108
E31.0 Autoimmune polyglandular failure
0.000 0.892 0.108
E32.9 Disease of thymus, unspecified
0.000 0.892 0.108
E32.8 Other diseases of thymus
0.000 0.892 0.108
E32.1 Abscess of thymus
0.000 0.892 0.108
E32.0 Persistent hyperplasia of thymus
0.000 0.892 0.108
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.892 0.108
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.892 0.108
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.892 0.108
E34.9 Endocrine disorder, unspecified
0.000 0.893 0.107
E34.0 Carcinoid syndrome
0.000 0.893 0.106
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.104 0.896 0.000
E22.1 Hyperprolactinaemia
0.000 0.896 0.104
E29.9 Testicular dysfunction, unspecified
0.000 0.897 0.103
E29.8 Other testicular dysfunction
0.000 0.897 0.103
E29.0 Testicular hyperfunction
0.000 0.897 0.103
E34.5 Androgen resistance syndrome
0.000 0.898 0.102
E34.4 Constitutional tall stature
0.000 0.898 0.102
E34.3 Short stature, not elsewhere classified
0.000 0.898 0.102
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.898 0.102
E34.1 Other hypersecretion of intestinal hormones
0.000 0.898 0.102
T43.0 Tricyclic and tetracyclic antidepressants
0.102 0.898 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.102 0.898 0.000
E20.8 Other hypoparathyroidism
0.000 0.899 0.101
E20.1 Pseudohypoparathyroidism
0.000 0.899 0.101
E20.0 Idiopathic hypoparathyroidism
0.000 0.899 0.101
T43.4 Butyrophenone and thioxanthene neuroleptics
0.101 0.899 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.099 0.901 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.099 0.901 0.000
T43.6 Psychostimulants with abuse potential
0.095 0.904 0.000
E29.1 Testicular hypofunction
0.000 0.905 0.095
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.906 0.094
E22.8 Other hyperfunction of pituitary gland
0.000 0.906 0.094
E24.2 Drug-induced Cushing's syndrome
0.000 0.906 0.094
E26.9 Hyperaldosteronism, unspecified
0.000 0.906 0.093
E26.8 Other hyperaldosteronism
0.000 0.906 0.093
E26.1 Secondary hyperaldosteronism
0.000 0.906 0.093
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.093 0.906 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.093 0.907 0.000
E24.8 Other Cushing's syndrome
0.000 0.907 0.093
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.907 0.093
E24.3 Ectopic ACTH syndrome
0.000 0.907 0.093
E24.1 Nelson's syndrome
0.000 0.907 0.093
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.908 0.092
E20.9 Hypoparathyroidism, unspecified
0.000 0.908 0.091
T47.1 Other antacids and anti-gastric-secretion drugs
0.090 0.910 0.000
T36 Poisoning by systemic antibiotics
0.090 0.910 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.090 0.910 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.911 0.089
E28.8 Other ovarian dysfunction
0.000 0.911 0.089
E28.1 Androgen excess
0.000 0.911 0.089
E28.0 Oestrogen excess
0.000 0.911 0.089
T46 Poisoning by agents primarily affecting the cardiovascular system
0.088 0.912 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.912 0.088
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.088 0.912 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.088 0.912 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.088 0.912 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.088 0.912 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.088 0.912 0.000
T44.0 Anticholinesterase agents
0.088 0.912 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.087 0.913 0.000
E28.3 Primary ovarian failure
0.000 0.913 0.086
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.086 0.914 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.086 0.914 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.086 0.914 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.086 0.914 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.086 0.914 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.085 0.915 0.000
T43.9 Psychotropic drug, unspecified
0.085 0.915 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.085 0.915 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.085 0.915 0.000
Chapter V Mental and behavioural disorders
0.084 0.916 0.000
E27.9 Disorder of adrenal gland, unspecified
0.001 0.916 0.084
E24.0 Pituitary-dependent Cushing's disease
0.000 0.916 0.084
F33 Recurrent depressive disorder
0.083 0.917 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.917 0.082
F30-F39 Mood [affective] disorders
0.083 0.917 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.918 0.082
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.082 0.918 0.000
T47.4 Other laxatives
0.082 0.918 0.000
L43 Lichen planus
0.079 0.920 0.001
F33.9 Recurrent depressive disorder, unspecified
0.080 0.920 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.080 0.920 0.000
E34.8 Other specified endocrine disorders
0.000 0.921 0.079
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.078 0.922 0.000
F60-F69 Disorders of adult personality and behaviour
0.078 0.922 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.922 0.077
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.077 0.923 0.000
F40 Phobic anxiety disorders
0.077 0.923 0.000
F60 Specific personality disorders
0.076 0.924 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.075 0.925 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.075 0.925 0.000
T47.7 Emetics
0.075 0.925 0.000
T47.6 Antidiarrhoeal drugs
0.075 0.925 0.000
T47.5 Digestants
0.075 0.925 0.000
T47.3 Saline and osmotic laxatives
0.075 0.925 0.000
T47.2 Stimulant laxatives
0.075 0.925 0.000
T47.0 Histamine H(2)-receptor antagonists
0.075 0.925 0.000
T50.8 Diagnostic agents
0.073 0.927 0.000
T50.7 Analeptics and opioid receptor antagonists
0.073 0.927 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.073 0.927 0.000
T50.5 Appetite depressants
0.073 0.927 0.000
T50.4 Drugs affecting uric acid metabolism
0.073 0.927 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.073 0.927 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.073 0.927 0.000
T50.1 Loop [high-ceiling] diuretics
0.073 0.927 0.000
T50.0 Mineralocorticoids and their antagonists
0.073 0.927 0.000
E26.0 Primary hyperaldosteronism
0.000 0.927 0.073
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.073 0.927 0.000
F40.2 Specific (isolated) phobias
0.073 0.927 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.072 0.928 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.072 0.928 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.072 0.928 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.071 0.929 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.071 0.929 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.071 0.929 0.000
T42.3 Barbiturates
0.071 0.929 0.000
T42.2 Succinimides and oxazolidinediones
0.071 0.929 0.000
F60.3 Emotionally unstable personality disorder
0.071 0.929 0.000
T45.0 Antiallergic and antiemetic drugs
0.070 0.929 0.000
F48 Other neurotic disorders
0.070 0.930 0.000
T38.1 Thyroid hormones and substitutes
0.070 0.930 0.000
T36.0 Penicillins
0.069 0.931 0.000
T42.0 Hydantoin derivatives
0.069 0.931 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.069 0.931 0.000
K90-K93 Other diseases of the digestive system
0.000 0.932 0.068
F52.2 Failure of genital response
0.068 0.932 0.000
F34 Persistent mood [affective] disorders
0.068 0.932 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.068 0.932 0.000
F25 Schizoaffective disorders
0.068 0.932 0.000
T42.1 Iminostilbenes
0.067 0.932 0.000
T38.9 Other and unspecified hormone antagonists
0.067 0.933 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.067 0.933 0.000
T38.7 Androgens and anabolic congeners
0.067 0.933 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.067 0.933 0.000
T38.5 Other oestrogens and progestogens
0.067 0.933 0.000
T38.4 Oral contraceptives
0.067 0.933 0.000
T38.2 Antithyroid drugs
0.067 0.933 0.000
T38.0 Glucocorticoids and synthetic analogues
0.067 0.933 0.000
F44 Dissociative [conversion] disorders
0.067 0.933 0.000
E14.9 Without complications
0.000 0.933 0.067
F20 Schizophrenia
0.067 0.933 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.933 0.067
T46.5 Other antihypertensive drugs, not elsewhere classified
0.066 0.934 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.065 0.934 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.065 0.935 0.000
T36.9 Systemic antibiotic, unspecified
0.065 0.935 0.000
T36.8 Other systemic antibiotics
0.065 0.935 0.000
T36.7 Antifungal antibiotics, systemically used
0.065 0.935 0.000
T36.6 Rifamycins
0.065 0.935 0.000
T36.5 Aminoglycosides
0.065 0.935 0.000
T36.4 Tetracyclines
0.065 0.935 0.000
T36.3 Macrolides
0.065 0.935 0.000
T36.2 Chloramphenicol group
0.065 0.935 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.065 0.935 0.000
F22 Persistent delusional disorders
0.064 0.936 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.936 0.064
F60.7 Dependent personality disorder
0.064 0.936 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.063 0.936 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.063 0.936 0.000
T46.7 Peripheral vasodilators
0.063 0.936 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.063 0.936 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.063 0.936 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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