TreeWAS – Variant ID: rs4629772

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
G57.6 Lesion of plantar nerve	0.000	0.945	0.055
G57 Mononeuropathies of lower limb	0.000	0.980	0.020
G57.0 Lesion of sciatic nerve	0.000	0.984	0.016
G57.9 Mononeuropathy of lower limb, unspecified	0.000	0.985	0.015
G57.3 Lesion of lateral popliteal nerve	0.000	0.985	0.015
G57.4 Lesion of medial popliteal nerve	0.000	0.985	0.014
G57.2 Lesion of femoral nerve	0.000	0.985	0.014
G57.5 Tarsal tunnel syndrome	0.000	0.985	0.014
Z09.0 Follow-up examination after surgery for other conditions	0.000	0.986	0.014
G57.1 Meralgia paraesthetica	0.000	0.987	0.012
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.988	0.012
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.989	0.011
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.989	0.011
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.989	0.011
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.000	0.989	0.011
Z09.2 Follow-up examination after chemotherapy for other conditions	0.000	0.990	0.010
G57.8 Other mononeuropathies of lower limb	0.000	0.990	0.010
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.010	0.990	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.990	0.010
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.991	0.009
Z09.8 Follow-up examination after other treatment for other conditions	0.000	0.991	0.009
Z09.7 Follow-up examination after combined treatment for other conditions	0.000	0.991	0.009
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.991	0.009
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.991	0.009
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.991	0.009
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.991	0.009
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.991	0.009
Z09.1 Follow-up examination after radiotherapy for other conditions	0.000	0.991	0.009
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.000	0.991	0.009
K13.7 Other and unspecified lesions of oral mucosa	0.000	0.992	0.008
I80 Phlebitis and thrombophlebitis	0.008	0.992	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.008	0.992	0.000
Z09.3 Follow-up examination after psychotherapy	0.000	0.992	0.008
N64.8 Other specified disorders of breast	0.008	0.992	0.000
Z09.4 Follow-up examination after treatment of fracture	0.000	0.992	0.008
N64.1 Fat necrosis of breast	0.008	0.992	0.000
N64 Other disorders of breast	0.007	0.993	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.007	0.993	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.007	0.993	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.007	0.993	0.000
N64.9 Disorder of breast, unspecified	0.006	0.994	0.000
N64.4 Mastodynia	0.006	0.994	0.000
M13.94 Arthritis, unspecified (Hand)	0.006	0.994	0.000
N64.3 Galactorrhoea not associated with childbirth	0.005	0.994	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.005	0.994	0.000
N64.2 Atrophy of breast	0.005	0.994	0.000
S72.40 Fracture of lower end of femur (closed)	0.000	0.994	0.005
M84 Disorders of continuity of bone	0.000	0.995	0.005
N64.0 Fissure and fistula of nipple	0.005	0.995	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.005	0.995	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.005	0.995	0.000
S72.4 Fracture of lower end of femur	0.000	0.995	0.005
M13.9 Arthritis, unspecified	0.005	0.995	0.000
M84.0 Malunion of fracture	0.000	0.996	0.004
M13.96 Arthritis, unspecified (Lower leg)	0.004	0.996	0.000
M84.9 Disorder of continuity of bone, unspecified	0.000	0.996	0.004
M84.8 Other disorders of continuity of bone	0.000	0.996	0.004
M84.3 Stress fracture, not elsewhere classified	0.000	0.996	0.004
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.000	0.996	0.004
S72.41 Fracture of lower end of femur (open)	0.000	0.996	0.004
M84.2 Delayed union of fracture	0.000	0.996	0.004
S72.00 Fracture of neck of femur (closed)	0.000	0.996	0.004
M84.4 Pathological fracture, not elsewhere classified	0.000	0.996	0.004
M67.8 Other specified disorders of synovium and tendon	0.004	0.996	0.000
S72 Fracture of femur	0.000	0.996	0.004
M84.01 Malunion of fracture (Shoulder region)	0.000	0.996	0.004
S72.0 Fracture of neck of femur	0.000	0.996	0.004
M84.02 Malunion of fracture (Upper arm)	0.000	0.996	0.004
M13.93 Arthritis, unspecified (Forearm)	0.004	0.996	0.000
M13.92 Arthritis, unspecified (Upper arm)	0.004	0.996	0.000
E21.0 Primary hyperparathyroidism	0.000	0.996	0.004
M84.06 Malunion of fracture (Lower leg)	0.000	0.996	0.003
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.997	0.003
M84.09 Malunion of fracture (Site unspecified)	0.000	0.997	0.003
M84.00 Malunion of fracture (Multiple sites)	0.000	0.997	0.003
M84.04 Malunion of fracture (Hand)	0.000	0.997	0.003
S02.20 Fracture of nasal bones (closed)	0.003	0.997	0.000
M84.08 Malunion of fracture (Other)	0.000	0.997	0.003
M84.03 Malunion of fracture (Forearm)	0.000	0.997	0.003
M84.05 Malunion of fracture (Pelvic region and thigh)	0.000	0.997	0.003
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.000	0.997	0.003
M84.98 Disorder of continuity of bone, unspecified (Other)	0.000	0.997	0.003
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.000	0.997	0.003
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.000	0.997	0.003
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.000	0.997	0.003
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.000	0.997	0.003
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.000	0.997	0.003
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.000	0.997	0.003
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.000	0.997	0.003
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.000	0.997	0.003
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.997	0.003
M84.89 Other disorders of continuity of bone (Site unspecified)	0.000	0.997	0.003
M84.88 Other disorders of continuity of bone (Other)	0.000	0.997	0.003
M84.86 Other disorders of continuity of bone (Lower leg)	0.000	0.997	0.003
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.000	0.997	0.003
M84.84 Other disorders of continuity of bone (Hand)	0.000	0.997	0.003
M84.82 Other disorders of continuity of bone (Upper arm)	0.000	0.997	0.003
M84.81 Other disorders of continuity of bone (Shoulder region)	0.000	0.997	0.003
M84.80 Other disorders of continuity of bone (Multiple sites)	0.000	0.997	0.003
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.000	0.997	0.003
M84.38 Stress fracture, not elsewhere classified (Other)	0.000	0.997	0.003
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.000	0.997	0.003
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.997	0.003
M84.34 Stress fracture, not elsewhere classified (Hand)	0.000	0.997	0.003
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.000	0.997	0.003
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.000	0.997	0.003
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.000	0.997	0.003
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.000	0.997	0.003
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.000	0.997	0.003
M84.83 Other disorders of continuity of bone (Forearm)	0.000	0.997	0.003
S72.8 Fractures of other parts of femur	0.000	0.997	0.003
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.997	0.003
D35.2 Pituitary gland	0.000	0.997	0.003
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.000	0.997	0.003
E10.9 Without complications	0.000	0.997	0.003
S61.8 Open wound of other parts of wrist and hand	0.000	0.997	0.003
M84.22 Delayed union of fracture (Upper arm)	0.000	0.997	0.003
S72.7 Multiple fractures of femur	0.000	0.997	0.003
M84.29 Delayed union of fracture (Site unspecified)	0.000	0.997	0.003
M84.28 Delayed union of fracture (Other)	0.000	0.997	0.003
M84.24 Delayed union of fracture (Hand)	0.000	0.997	0.003
M84.23 Delayed union of fracture (Forearm)	0.000	0.997	0.003
M84.21 Delayed union of fracture (Shoulder region)	0.000	0.997	0.003
M84.20 Delayed union of fracture (Multiple sites)	0.000	0.997	0.003
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.003	0.997	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.000	0.997	0.003
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.000	0.997	0.003
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.000	0.997	0.003
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.000	0.997	0.003
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.000	0.997	0.003
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.000	0.997	0.003
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.000	0.997	0.003
M13.98 Arthritis, unspecified (Other)	0.003	0.997	0.000
E27.2 Addisonian crisis	0.000	0.997	0.003
D35.1 Parathyroid gland	0.000	0.997	0.003
S72.9 Fracture of femur, part unspecified	0.000	0.997	0.003
S72.3 Fracture of shaft of femur	0.000	0.997	0.003
M67 Other disorders of synovium and tendon	0.003	0.997	0.000
S72.01 Fracture of neck of femur (open)	0.000	0.997	0.003
M67.1 Other contracture of tendon (sheath)	0.003	0.997	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.000	0.997	0.003
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.000	0.997	0.003
M25.55 Pain in joint (Pelvic region and thigh)	0.003	0.997	0.000
M84.26 Delayed union of fracture (Lower leg)	0.000	0.997	0.003
S72.2 Subtrochanteric fracture	0.000	0.997	0.003
E20-E35 Disorders of other endocrine glands	0.000	0.997	0.003
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.000	0.997	0.003
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.997	0.003
S72.80 Fractures of other parts of femur (closed)	0.000	0.997	0.003
N64.5 Other signs and symptoms in breast	0.003	0.997	0.000
E27 Other disorders of adrenal gland	0.000	0.997	0.003
E23 Hypofunction and other disorders of pituitary gland	0.000	0.997	0.003
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.997	0.003
E21.4 Other specified disorders of parathyroid gland	0.000	0.997	0.003
S72.1 Pertrochanteric fracture	0.000	0.997	0.003
E20 Hypoparathyroidism	0.000	0.997	0.003
M67.2 Synovial hypertrophy, not elsewhere classified	0.003	0.997	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.000	0.997	0.002
M13 Other arthritis	0.003	0.997	0.000
S72.70 Multiple fractures of femur (closed)	0.000	0.997	0.002
S72.81 Fractures of other parts of femur (open)	0.000	0.997	0.002
E23.7 Disorder of pituitary gland, unspecified	0.000	0.997	0.003
E22 Hyperfunction of pituitary gland	0.000	0.997	0.003
E27.1 Primary adrenocortical insufficiency	0.000	0.997	0.002
E34 Other endocrine disorders	0.000	0.997	0.002
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.002	0.997	0.000
S72.71 Multiple fractures of femur (open)	0.000	0.997	0.002
E21.2 Other hyperparathyroidism	0.000	0.997	0.002
S72.30 Fracture of shaft of femur (closed)	0.000	0.998	0.002
D35 Benign neoplasm of other and unspecified endocrine glands	0.000	0.998	0.002
M67.0 Short Achilles tendon (acquired)	0.002	0.998	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.998	0.002
F40.2 Specific (isolated) phobias	0.000	0.998	0.002
E25 Adrenogenital disorders	0.000	0.998	0.002
M79.60 Pain in limb (Multiple sites)	0.000	0.998	0.002
E20.9 Hypoparathyroidism, unspecified	0.000	0.998	0.002
S72.91 Fracture of femur, part unspecified (open)	0.000	0.998	0.002
M67.9 Disorder of synovium and tendon, unspecified	0.002	0.998	0.000
M67.3 Transient synovitis	0.002	0.998	0.000
E31 Polyglandular dysfunction	0.000	0.998	0.002
S72.90 Fracture of femur, part unspecified (closed)	0.000	0.998	0.002
E28 Ovarian dysfunction	0.000	0.998	0.002
S72.21 Subtrochanteric fracture (open)	0.000	0.998	0.002
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.998	0.002
E30 Disorders of puberty, not elsewhere classified	0.000	0.998	0.002
E23.2 Diabetes insipidus	0.000	0.998	0.002
E26 Hyperaldosteronism	0.000	0.998	0.002
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.998	0.002
E34.8 Other specified endocrine disorders	0.000	0.998	0.002
E34.3 Short stature, not elsewhere classified	0.000	0.998	0.002
S72.31 Fracture of shaft of femur (open)	0.000	0.998	0.002
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.998	0.002
M13.1 Monoarthritis, not elsewhere classified	0.002	0.998	0.000
E20.8 Other hypoparathyroidism	0.000	0.998	0.002
M13.97 Arthritis, unspecified (Ankle and foot)	0.002	0.998	0.000
E27.5 Adrenomedullary hyperfunction	0.000	0.998	0.002
E27.0 Other adrenocortical overactivity	0.000	0.998	0.002
N60.0 Solitary cyst of breast	0.002	0.998	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.000	0.998	0.002
E32 Diseases of thymus	0.000	0.998	0.002
S72.20 Subtrochanteric fracture (closed)	0.000	0.998	0.002
M67.4 Ganglion	0.002	0.998	0.000
R29.6 Tendency to fall, not elsewhere classified	0.000	0.998	0.002
E22.1 Hyperprolactinaemia	0.000	0.998	0.002
E23.1 Drug-induced hypopituitarism	0.000	0.998	0.002
E23.0 Hypopituitarism	0.000	0.998	0.002
M13.8 Other specified arthritis	0.002	0.998	0.000
M10.99 Gout, unspecified (Site unspecified)	0.002	0.998	0.000
S72.11 Pertrochanteric fracture (open)	0.000	0.998	0.002
E20.1 Pseudohypoparathyroidism	0.000	0.998	0.002
E22.0 Acromegaly and pituitary gigantism	0.000	0.998	0.002
E20.0 Idiopathic hypoparathyroidism	0.000	0.998	0.002
E23.6 Other disorders of pituitary gland	0.000	0.998	0.002
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.998	0.002
E22.8 Other hyperfunction of pituitary gland	0.000	0.998	0.002
E29 Testicular dysfunction	0.000	0.998	0.002
E27.9 Disorder of adrenal gland, unspecified	0.000	0.998	0.002
S02.2 Fracture of nasal bones	0.002	0.998	0.000
K13 Other diseases of lip and oral mucosa	0.000	0.998	0.002
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.998	0.002
E27.8 Other specified disorders of adrenal gland	0.000	0.998	0.002
E34.5 Androgen resistance syndrome	0.000	0.998	0.002
E34.4 Constitutional tall stature	0.000	0.998	0.002
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.998	0.002
E34.1 Other hypersecretion of intestinal hormones	0.000	0.998	0.002
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.998	0.002
E24 Cushing's syndrome	0.000	0.998	0.002
D35.9 Endocrine gland, unspecified	0.000	0.998	0.002
D35.8 Pluriglandular involvement	0.000	0.998	0.002
D35.7 Other specified endocrine glands	0.000	0.998	0.002
D35.6 Aortic body and other paraganglia	0.000	0.998	0.002
D35.5 Carotid body	0.000	0.998	0.002
D35.4 Pineal gland	0.000	0.998	0.002
D35.3 Craniopharyngeal duct	0.000	0.998	0.002
E31.0 Autoimmune polyglandular failure	0.000	0.998	0.002
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.000	0.998	0.002
E26.0 Primary hyperaldosteronism	0.000	0.998	0.002
M80-M85 Disorders of bone density and structure	0.000	0.998	0.002
M13.16 Monoarthritis, not elsewhere classified (Lower leg)	0.002	0.998	0.000
E25.9 Adrenogenital disorder, unspecified	0.000	0.998	0.002
E25.8 Other adrenogenital disorders	0.000	0.998	0.002
E28.3 Primary ovarian failure	0.000	0.998	0.002
K65.9 Peritonitis, unspecified	0.002	0.998	0.000
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.002	0.998	0.000
E31.9 Polyglandular dysfunction, unspecified	0.000	0.998	0.002
E31.8 Other polyglandular dysfunction	0.000	0.998	0.002
E31.1 Polyglandular hyperfunction	0.000	0.998	0.002
D35.0 Adrenal gland	0.000	0.998	0.002
E28.9 Ovarian dysfunction, unspecified	0.000	0.998	0.002
E28.8 Other ovarian dysfunction	0.000	0.998	0.002
E28.1 Androgen excess	0.000	0.998	0.002
E28.0 Oestrogen excess	0.000	0.998	0.002
E30.9 Disorder of puberty, unspecified	0.000	0.998	0.002
E30.8 Other disorders of puberty	0.000	0.998	0.002
E30.1 Precocious puberty	0.000	0.998	0.002
E30.0 Delayed puberty	0.000	0.998	0.002
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.998	0.002
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.998	0.002
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.998	0.002
S70 Superficial injury of hip and thigh	0.000	0.998	0.002
M13.17 Monoarthritis, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
E26.8 Other hyperaldosteronism	0.000	0.998	0.002
E26.1 Secondary hyperaldosteronism	0.000	0.998	0.002
E34.0 Carcinoid syndrome	0.000	0.998	0.002
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.000	0.998	0.002
S70.9 Superficial injury of hip and thigh, unspecified	0.000	0.998	0.002
M13.19 Monoarthritis, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M13.18 Monoarthritis, not elsewhere classified (Other)	0.002	0.998	0.000
M13.15 Monoarthritis, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M13.14 Monoarthritis, not elsewhere classified (Hand)	0.002	0.998	0.000
M13.13 Monoarthritis, not elsewhere classified (Forearm)	0.002	0.998	0.000
M13.12 Monoarthritis, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M13.11 Monoarthritis, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M13.10 Monoarthritis, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
M13.89 Other specified arthritis (Site unspecified)	0.002	0.998	0.000
M13.84 Other specified arthritis (Hand)	0.002	0.998	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.998	0.002
E28.2 Polycystic ovarian syndrome	0.000	0.998	0.002
E34.9 Endocrine disorder, unspecified	0.000	0.998	0.002
R26.8 Other and unspecified abnormalities of gait and mobility	0.000	0.998	0.002
M13.83 Other specified arthritis (Forearm)	0.002	0.998	0.000
E32.1 Abscess of thymus	0.000	0.998	0.002
E32.0 Persistent hyperplasia of thymus	0.000	0.998	0.002
M13.86 Other specified arthritis (Lower leg)	0.002	0.998	0.000
M67.49 Ganglion, multiple sites	0.002	0.998	0.000
M67.45 Ganglion, hip	0.002	0.998	0.000
N21.0 Calculus in bladder	0.002	0.998	0.000
S70-S79 Injuries to the hip and thigh	0.000	0.998	0.002
M13.88 Other specified arthritis (Other)	0.002	0.998	0.000
M13.85 Other specified arthritis (Pelvic region and thigh)	0.002	0.998	0.000
M13.82 Other specified arthritis (Upper arm)	0.002	0.998	0.000
M13.81 Other specified arthritis (Shoulder region)	0.002	0.998	0.000
S02.21 Fracture of nasal bones (open)	0.002	0.998	0.000
M13.87 Other specified arthritis (Ankle and foot)	0.002	0.998	0.000
S72.10 Pertrochanteric fracture (closed)	0.000	0.998	0.002
E26.9 Hyperaldosteronism, unspecified	0.000	0.998	0.002
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.998	0.002
E32.9 Disease of thymus, unspecified	0.000	0.998	0.002
E32.8 Other diseases of thymus	0.000	0.998	0.002
M67.47 Ganglion, ankle and foot	0.002	0.998	0.000
C85.1 B-cell lymphoma, unspecified	0.000	0.998	0.002
M85.8 Other specified disorders of bone density and structure	0.000	0.998	0.002
M13.80 Other specified arthritis (Multiple sites)	0.002	0.998	0.000
E10.0 With coma	0.000	0.998	0.002
E29.9 Testicular dysfunction, unspecified	0.000	0.998	0.002
E29.8 Other testicular dysfunction	0.000	0.998	0.002
E29.0 Testicular hyperfunction	0.000	0.998	0.002
F43.2 Adjustment disorders	0.000	0.998	0.002
M81.4 Drug-induced osteoporosis	0.000	0.998	0.002
C62.9 Testis, unspecified	0.000	0.998	0.002
S70.1 Contusion of thigh	0.000	0.998	0.002
M67.43 Ganglion, wrist	0.002	0.998	0.000
E24.0 Pituitary-dependent Cushing's disease	0.000	0.998	0.002
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue	0.000	0.998	0.002
K13.3 Hairy leukoplakia	0.000	0.998	0.002
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.998	0.002
E24.3 Ectopic ACTH syndrome	0.000	0.998	0.002
E24.1 Nelson's syndrome	0.000	0.998	0.002
M13.0 Polyarthritis, unspecified	0.001	0.998	0.001
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.998	0.002
E24.8 Other Cushing's syndrome	0.000	0.998	0.002
S70.0 Contusion of hip	0.000	0.998	0.002
M82 Osteoporosis in diseases classified elsewhere	0.000	0.998	0.002
K13.5 Oral submucous fibrosis	0.000	0.998	0.002
L43.9 Lichen planus, unspecified	0.000	0.998	0.002
M83 Adult osteomalacia	0.000	0.998	0.002
K13.1 Cheek and lip biting	0.000	0.998	0.002
K65.0 Acute peritonitis	0.002	0.998	0.000
M85 Other disorders of bone density and structure	0.000	0.998	0.002
S71 Open wound of hip and thigh	0.000	0.998	0.002
E16.2 Hypoglycaemia, unspecified	0.000	0.998	0.002
M14.6 Neuropathic arthropathy	0.002	0.998	0.000
E24.2 Drug-induced Cushing's syndrome	0.000	0.998	0.001
S70.7 Multiple superficial injuries of hip and thigh	0.000	0.998	0.002
M81 Osteoporosis without pathological fracture	0.000	0.998	0.002
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.000	0.998	0.001
S71.0 Open wound of hip	0.000	0.998	0.002
Z73.3 Stress, not elsewhere classified	0.000	0.998	0.002
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.998	0.001
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.000	0.998	0.001
K42.9 Umbilical hernia without obstruction or gangrene	0.002	0.998	0.000
S70.8 Other superficial injuries of hip and thigh	0.000	0.998	0.001
E10 Insulin-dependent diabetes mellitus	0.000	0.998	0.002
K13.6 Irritative hyperplasia of oral mucosa	0.000	0.998	0.001
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.002	0.998	0.000
S78 Traumatic amputation of hip and thigh	0.000	0.998	0.001
S77 Crushing injury of hip and thigh	0.000	0.998	0.001
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.000	0.998	0.002
G50-G59 Nerve, nerve root and plexus disorders	0.000	0.998	0.002
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.000	0.998	0.001
D68.9 Coagulation defect, unspecified	0.002	0.998	0.000
M10.9 Gout, unspecified	0.002	0.998	0.000
S75 Injury of blood vessels at hip and thigh level	0.000	0.998	0.001
S74 Injury of nerves at hip and thigh level	0.000	0.998	0.001
M25.74 Osteophyte (Hand)	0.000	0.998	0.001
M81.48 Drug-induced osteoporosis (Other)	0.000	0.998	0.001
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.000	0.998	0.001
M81.46 Drug-induced osteoporosis (Lower leg)	0.000	0.998	0.001
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.000	0.998	0.001
M81.44 Drug-induced osteoporosis (Hand)	0.000	0.998	0.001
M81.43 Drug-induced osteoporosis (Forearm)	0.000	0.998	0.001
M81.42 Drug-induced osteoporosis (Upper arm)	0.000	0.998	0.001
M81.41 Drug-induced osteoporosis (Shoulder region)	0.000	0.998	0.001
M85.88 Other specified disorders of bone density and structure (Other)	0.000	0.998	0.001
M85.84 Other specified disorders of bone density and structure (Hand)	0.000	0.998	0.001
E24.9 Cushing's syndrome, unspecified	0.000	0.998	0.001
E29.1 Testicular hypofunction	0.000	0.998	0.001
F31.9 Bipolar affective disorder, unspecified	0.000	0.998	0.002
Y42.5 Other oestrogens and progestogens	0.002	0.998	0.000
F40 Phobic anxiety disorders	0.000	0.998	0.002
M10.94 Gout, unspecified (Hand)	0.001	0.998	0.000
M13.06 Polyarthritis, unspecified (Lower leg)	0.001	0.998	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.000	0.998	0.001
M85.83 Other specified disorders of bone density and structure (Forearm)	0.000	0.998	0.001
D37.4 Colon	0.002	0.998	0.000
L43.8 Other lichen planus	0.000	0.998	0.001
S76 Injury of muscle and tendon at hip and thigh level	0.000	0.998	0.001
K13.29 Other disturbances of oral epithelium, including tongue	0.000	0.998	0.001
M13.08 Polyarthritis, unspecified (Other)	0.001	0.998	0.001
M13.07 Polyarthritis, unspecified (Ankle and foot)	0.001	0.998	0.001
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)	0.001	0.998	0.001
M13.03 Polyarthritis, unspecified (Forearm)	0.001	0.998	0.001
M13.02 Polyarthritis, unspecified (Upper arm)	0.001	0.998	0.001
M13.01 Polyarthritis, unspecified (Shoulder region)	0.001	0.998	0.001
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.000	0.998	0.001
M82.1 Osteoporosis in endocrine disorders	0.000	0.998	0.001
M83.3 Adult osteomalacia due to malnutrition	0.000	0.998	0.001
W19.4 Street and highway	0.002	0.998	0.000
M14 Arthropathies in other diseases classified elsewhere	0.001	0.998	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.000	0.998	0.001
M82.8 Osteoporosis in other diseases classified elsewhere	0.000	0.998	0.001
M82.0 Osteoporosis in multiple myelomatosis	0.000	0.998	0.001
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.000	0.998	0.001
M83.9 Adult osteomalacia, unspecified	0.000	0.998	0.001
M83.5 Other drug-induced osteomalacia in adults	0.000	0.998	0.001
M83.4 Aluminum bone disease	0.000	0.998	0.001
M83.2 Adult osteomalacia due to malabsorption	0.000	0.998	0.001
M83.0 Puerperal osteomalacia	0.000	0.998	0.001
K65 Peritonitis	0.002	0.998	0.000
M10 Gout	0.001	0.998	0.000
M13.04 Polyarthritis, unspecified (Hand)	0.001	0.998	0.001
L91.8 Other hypertrophic disorders of skin	0.002	0.998	0.000
M83.8 Other adult osteomalacia	0.000	0.998	0.001
M83.1 Senile osteomalacia	0.000	0.998	0.001
M85.5 Aneurysmal bone cyst	0.000	0.998	0.001
M85.3 Osteitis condensans	0.000	0.998	0.001
M85.1 Skeletal fluorosis	0.000	0.998	0.001
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.000	0.998	0.001
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.001	0.998	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.000	0.998	0.001
M81.8 Other osteoporosis	0.000	0.998	0.001
M81.1 Postoophorectomy osteoporosis	0.000	0.998	0.001
Z01.8 Other specified special examinations	0.000	0.998	0.001
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.000	0.998	0.001
M10.96 Gout, unspecified (Lower leg)	0.001	0.999	0.000
M13.09 Polyarthritis, unspecified (Site unspecified)	0.001	0.999	0.001
M81.6 Localised osteoporosis [Lequesne]	0.000	0.999	0.001
M81.5 Idiopathic osteoporosis	0.000	0.999	0.001
M85.4 Solitary bone cyst	0.000	0.999	0.001
S71.7 Multiple open wounds of of hip and thigh	0.000	0.999	0.001
M05-M14 Inflammatory polyarthropathies	0.001	0.999	0.000
E10.8 With unspecified complications	0.000	0.999	0.001
M81.0 Postmenopausal osteoporosis	0.000	0.999	0.001
M85.9 Disorder of bone density and structure, unspecified	0.000	0.999	0.001
S71.1 Open wound of thigh	0.000	0.999	0.001
M13.00 Polyarthritis, unspecified (Multiple sites)	0.001	0.999	0.001
E10.6 With other specified complications	0.000	0.999	0.001
E10.5 With peripheral circulatory complications	0.000	0.999	0.001
M85.2 Hyperostosis of skull	0.000	0.999	0.001
S77.2 Crushing injury of hip with thigh	0.000	0.999	0.001
S77.1 Crushing injury of thigh	0.000	0.999	0.001
S77.0 Crushing injury of hip	0.000	0.999	0.001
S78.9 Traumatic amputation of hip and thigh, level unspecified	0.000	0.999	0.001
S78.1 Traumatic amputation at level between hip and knee	0.000	0.999	0.001
S78.0 Traumatic amputation at hip joint	0.000	0.999	0.001
L43 Lichen planus	0.000	0.999	0.001
S79 Other and unspecified injuries of hip and thigh	0.000	0.999	0.001
M10.98 Gout, unspecified (Other)	0.001	0.999	0.000
M10.95 Gout, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M10.91 Gout, unspecified (Shoulder region)	0.001	0.999	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.000	0.999	0.001
M83.30 Adult osteomalacia due to malnutrition (Multiple sites)	0.000	0.999	0.001
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.000	0.999	0.001
E10.7 With multiple complications	0.000	0.999	0.001
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.999	0.001
M85.6 Other cyst of bone	0.000	0.999	0.001
Q21.1 Atrial septal defect	0.001	0.999	0.000
S73.1 Sprain and strain of hip	0.000	0.999	0.001
S74.9 Injury of unspecified nerve at hip and thigh level	0.000	0.999	0.001
S74.8 Injury of other nerves at hip and thigh level	0.000	0.999	0.001
S74.7 Injury of multiple nerves at hip and thigh level	0.000	0.999	0.001
S74.2 Injury of cutaneous sensory nerve at hip and thigh level	0.000	0.999	0.001
S74.1 Injury of femoral nerve at hip and thigh level	0.000	0.999	0.001
S75.9 Injury of unspecified blood vessel at hip and thigh level	0.000	0.999	0.001
S75.8 Injury of other blood vessels at hip and thigh level	0.000	0.999	0.001
S75.7 Injury of multiple blood vessels at hip and thigh level	0.000	0.999	0.001
S75.2 Injury of greater saphenous vein at hip and thigh level	0.000	0.999	0.001
S75.1 Injury of femoral vein at hip and thigh level	0.000	0.999	0.001
F43 Reaction to severe stress, and adjustment disorders	0.000	0.999	0.001
F40.1 Social phobias	0.000	0.999	0.001
G55.0 Nerve root and plexus compressions in neoplastic disease	0.000	0.999	0.001
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.001	0.999	0.000
S76.4 Injury of other and unspecified muscles and tendons at thigh level	0.000	0.999	0.001
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.001	0.999	0.000
Z73 Problems related to life-management difficulty	0.000	0.999	0.001
M83.39 Adult osteomalacia due to malnutrition (Site unspecified)	0.000	0.999	0.001
M83.38 Adult osteomalacia due to malnutrition (Other)	0.000	0.999	0.001
M83.37 Adult osteomalacia due to malnutrition (Ankle and foot)	0.000	0.999	0.001
M83.36 Adult osteomalacia due to malnutrition (Lower leg)	0.000	0.999	0.001
M83.35 Adult osteomalacia due to malnutrition (Pelvic region and thigh)	0.000	0.999	0.001
M83.34 Adult osteomalacia due to malnutrition (Hand)	0.000	0.999	0.001
M83.33 Adult osteomalacia due to malnutrition (Forearm)	0.000	0.999	0.001
M83.32 Adult osteomalacia due to malnutrition (Upper arm)	0.000	0.999	0.001
M83.31 Adult osteomalacia due to malnutrition (Shoulder region)	0.000	0.999	0.001
F40.9 Phobic anxiety disorder, unspecified	0.000	0.999	0.001
F40.0 Agoraphobia	0.000	0.999	0.001
L91.0 Keloid scar	0.001	0.999	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.001	0.999	0.000
M14.4 Arthropathy in amyloidosis	0.001	0.999	0.000
M14.3 Lipoid dermatoarthritis	0.001	0.999	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.001	0.999	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.001	0.999	0.000
M85.0 Fibrous dysplasia (monostotic)	0.000	0.999	0.001
S74.0 Injury of sciatic nerve at hip and thigh level	0.000	0.999	0.001
S76.1 Injury of quadriceps muscle and tendon	0.000	0.999	0.001
S76.7 Injury of multiple muscles and tendons at hip and thigh level	0.000	0.999	0.001
S76.2 Injury of adductor muscle and tendon of thigh	0.000	0.999	0.001
G20 Parkinson's disease	0.000	0.999	0.001
M12 Other specific arthropathies	0.001	0.999	0.000
R15 Faecal incontinence	0.001	0.999	0.000
M81.80 Other osteoporosis (Multiple sites)	0.000	0.999	0.001
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)	0.000	0.999	0.001
M82.08 Osteoporosis in multiple myelomatosis (Other)	0.000	0.999	0.001
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)	0.000	0.999	0.001
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)	0.000	0.999	0.001
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)	0.000	0.999	0.001
M82.04 Osteoporosis in multiple myelomatosis (Hand)	0.000	0.999	0.001
M82.03 Osteoporosis in multiple myelomatosis (Forearm)	0.000	0.999	0.001
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations