TreeWAS – Variant ID: rs4674024

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Y40.0 Penicillins	0.527	0.473	0.000
Y40 Systemic antibiotics	0.525	0.475	0.000
Y40.8 Other systemic antibiotics	0.525	0.475	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.421	0.579	0.000
Y40.4 Tetracyclines	0.414	0.586	0.000
Y40.9 Systemic antibiotic, unspecified	0.409	0.591	0.000
Y40.3 Macrolides	0.400	0.599	0.000
Y40.6 Rifamycins	0.400	0.600	0.000
Y40.7 Antifungal antibiotics, systemically used	0.386	0.614	0.000
Y40.2 Chloramphenicol group	0.376	0.624	0.000
Y40.5 Aminoglycosides	0.375	0.625	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.083	0.917	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.083	0.917	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.080	0.920	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.079	0.921	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.078	0.922	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.078	0.922	0.000
C92.0 Acute myeloid leukaemia	0.075	0.925	0.000
T36 Poisoning by systemic antibiotics	0.074	0.926	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.074	0.926	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.072	0.927	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.072	0.928	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.072	0.928	0.000
T46.1 Calcium-channel blockers	0.071	0.929	0.000
C92 Myeloid leukaemia	0.071	0.929	0.000
T40.4 Other synthetic narcotics	0.070	0.930	0.000
T40.6 Other and unspecified narcotics	0.070	0.930	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.070	0.930	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.068	0.932	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.065	0.935	0.000
T38.1 Thyroid hormones and substitutes	0.065	0.935	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.064	0.936	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.064	0.936	0.000
C92.9 Myeloid leukaemia, unspecified	0.064	0.936	0.000
T36.0 Penicillins	0.063	0.937	0.000
T40.3 Methadone	0.063	0.937	0.000
C92.1 Chronic myeloid leukaemia	0.062	0.938	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.060	0.940	0.000
T36.8 Other systemic antibiotics	0.060	0.940	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.060	0.940	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.060	0.940	0.000
T46.7 Peripheral vasodilators	0.060	0.940	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.060	0.940	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.059	0.941	0.000
T45.0 Antiallergic and antiemetic drugs	0.059	0.941	0.000
C92.4 Acute promyelocytic leukaemia	0.058	0.942	0.000
T45.2 Vitamins, not elsewhere classified	0.058	0.942	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.058	0.942	0.000
C92.7 Other myeloid leukaemia	0.058	0.942	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.057	0.943	0.000
C92.2 Subacute myeloid leukaemia	0.057	0.943	0.000
T40.5 Cocaine	0.057	0.943	0.000
T45.5 Anticoagulants	0.057	0.943	0.000
T38.9 Other and unspecified hormone antagonists	0.057	0.943	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.057	0.943	0.000
T38.7 Androgens and anabolic congeners	0.057	0.943	0.000
T38.5 Other oestrogens and progestogens	0.057	0.943	0.000
T38.4 Oral contraceptives	0.057	0.943	0.000
T38.2 Antithyroid drugs	0.057	0.943	0.000
T38.0 Glucocorticoids and synthetic analogues	0.057	0.943	0.000
T36.3 Macrolides	0.057	0.943	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.056	0.944	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.056	0.944	0.000
T40.8 Lysergide [LSD]	0.056	0.944	0.000
T40.7 Cannabis (derivatives)	0.056	0.944	0.000
T40.0 Opium	0.056	0.944	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.056	0.944	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.056	0.944	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.056	0.944	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.056	0.944	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.056	0.944	0.000
T44.0 Anticholinesterase agents	0.056	0.944	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.055	0.945	0.000
T47.2 Stimulant laxatives	0.055	0.945	0.000
T40.1 Heroin	0.055	0.945	0.000
T36.4 Tetracyclines	0.054	0.946	0.000
T36.9 Systemic antibiotic, unspecified	0.053	0.947	0.000
T36.7 Antifungal antibiotics, systemically used	0.053	0.947	0.000
T36.6 Rifamycins	0.053	0.947	0.000
T36.5 Aminoglycosides	0.053	0.947	0.000
T36.2 Chloramphenicol group	0.053	0.947	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.053	0.947	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.052	0.948	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.052	0.948	0.000
T45.8 Other primarily systemic and haematological agents	0.052	0.948	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.052	0.948	0.000
T45.6 Fibrinolysis-affecting drugs	0.052	0.948	0.000
T45.4 Iron and its compounds	0.052	0.948	0.000
T45.3 Enzymes, not elsewhere classified	0.052	0.948	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.052	0.948	0.000
T47.0 Histamine H(2)-receptor antagonists	0.052	0.948	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.051	0.949	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.051	0.949	0.000
C92.3 Myeloid sarcoma	0.051	0.949	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.050	0.950	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.050	0.950	0.000
T37.5 Antiviral drugs	0.050	0.950	0.000
T37.4 Anthelminthics	0.050	0.950	0.000
T37.3 Other antiprotozoal drugs	0.050	0.950	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.050	0.950	0.000
T37.1 Antimycobacterial drugs	0.050	0.950	0.000
T37.0 Sulphonamides	0.050	0.950	0.000
C92.5 Acute myelomonocytic leukaemia	0.050	0.950	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.050	0.950	0.000
T47.6 Antidiarrhoeal drugs	0.049	0.950	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.049	0.951	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.049	0.951	0.000
T47.7 Emetics	0.049	0.951	0.000
T47.5 Digestants	0.049	0.951	0.000
T47.4 Other laxatives	0.049	0.951	0.000
T47.3 Saline and osmotic laxatives	0.049	0.951	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.048	0.952	0.000
T49.9 Topical agent, unspecified	0.046	0.954	0.000
T49.8 Other topical agents	0.046	0.954	0.000
T49.7 Dental drugs, topically applied	0.046	0.954	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.046	0.954	0.000
T49.5 Ophthalmological drugs and preparations	0.046	0.954	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.046	0.954	0.000
T49.3 Emollients, demulcents and protectants	0.046	0.954	0.000
T49.2 Local astringents and local detergents	0.046	0.954	0.000
T49.1 Antipruritics	0.046	0.954	0.000
T41.5 Therapeutic gases	0.043	0.957	0.000
T41.4 Anaesthetic, unspecified	0.043	0.957	0.000
T41.3 Local anaesthetics	0.043	0.957	0.000
T41.2 Other and unspecified general anaesthetics	0.043	0.957	0.000
T41.1 Intravenous anaesthetics	0.043	0.957	0.000
T41.0 Inhaled anaesthetics	0.043	0.957	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.043	0.957	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.037	0.963	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.036	0.964	0.000
T48.4 Expectorants	0.036	0.964	0.000
T48.3 Antitussives	0.036	0.964	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.036	0.964	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.036	0.964	0.000
T48.0 Oxytocic drugs	0.036	0.964	0.000
T40.2 Other opioids	0.035	0.965	0.000
T50.1 Loop [high-ceiling] diuretics	0.034	0.966	0.000
T48.5 Anti-common-cold drugs	0.033	0.966	0.000
T39.0 Salicylates	0.032	0.968	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.032	0.968	0.000
Z13.9 Special screening examination, unspecified	0.000	0.969	0.031
T50.7 Analeptics and opioid receptor antagonists	0.031	0.969	0.000
T50.5 Appetite depressants	0.031	0.969	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.031	0.969	0.000
T50.0 Mineralocorticoids and their antagonists	0.031	0.969	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.031	0.969	0.000
T50.4 Drugs affecting uric acid metabolism	0.031	0.969	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.029	0.971	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.029	0.971	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.028	0.971	0.000
T50.8 Diagnostic agents	0.028	0.972	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.027	0.973	0.000
T39.4 Antirheumatics, not elsewhere classified	0.027	0.973	0.000
T39.2 Pyrazolone derivatives	0.027	0.973	0.000
T42.0 Hydantoin derivatives	0.025	0.975	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.024	0.976	0.000
C25.0 Head of pancreas	0.000	0.977	0.023
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.023	0.977	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.023	0.977	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.021	0.979	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.020	0.979	0.000
T42.3 Barbiturates	0.020	0.979	0.000
T42.2 Succinimides and oxazolidinediones	0.020	0.979	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.019	0.980	0.000
T85.2 Mechanical complication of intraocular lens	0.018	0.982	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.018	0.982	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.017	0.983	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.016	0.983	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.015	0.984	0.000
F20.9 Schizophrenia, unspecified	0.000	0.985	0.015
M77.47 Metatarsalgia-Ankle/Foot	0.000	0.985	0.015
T42.1 Iminostilbenes	0.015	0.985	0.000
Q61.3 Polycystic kidney, unspecified	0.015	0.985	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.015	0.985	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.014	0.986	0.000
F20 Schizophrenia	0.000	0.986	0.014
S82.30 Fracture of lower end of tibia (closed)	0.000	0.986	0.014
T82.0 Mechanical complication of heart valve prosthesis	0.014	0.986	0.000
Q24 Other congenital malformations of heart	0.013	0.987	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.013	0.987	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.013	0.987	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.013	0.987	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.013	0.987	0.000
C25 Malignant neoplasm of pancreas	0.000	0.987	0.013
Q61 Cystic kidney disease	0.013	0.987	0.000
Q65 Congenital deformities of hip	0.013	0.987	0.000
Q65.8 Other congenital deformities of hip	0.012	0.987	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.012	0.988	0.000
Q23 Congenital malformations of aortic and mitral valves	0.012	0.988	0.000
Q44.6 Cystic disease of liver	0.012	0.988	0.000
Q60-Q64 Congenital malformations of the urinary system	0.012	0.988	0.000
Q25 Congenital malformations of great arteries	0.012	0.988	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.012	0.988	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.012	0.988	0.000
F20.0 Paranoid schizophrenia	0.000	0.988	0.012
Q24.0 Dextrocardia	0.011	0.988	0.000
F20.5 Residual schizophrenia	0.000	0.989	0.011
T87 Complications peculiar to reattachment and amputation	0.011	0.989	0.000
T80.2 Infections following infusion, transfusion and therapeutic injection	0.011	0.989	0.000
T87.4 Infection of amputation stump	0.011	0.989	0.000
Q43 Other congenital malformations of intestine	0.011	0.989	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.011	0.989	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.011	0.989	0.000
T87.6 Other and unspecified complications of amputation stump	0.011	0.989	0.000
T82.1 Mechanical complication of cardiac electronic device	0.011	0.989	0.000
Q23.0 Congenital stenosis of aortic valve	0.011	0.989	0.000
Q25.1 Coarctation of aorta	0.011	0.989	0.000
Q27 Other congenital malformations of peripheral vascular system	0.011	0.989	0.000
Q44.5 Other congenital malformations of bile ducts	0.011	0.989	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.011	0.989	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.011	0.989	0.000
Q40 Other congenital malformations of upper alimentary tract	0.011	0.989	0.000
C25.3 Pancreatic duct	0.000	0.989	0.011
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.011	0.989	0.000
Q76 Congenital malformations of spine and bony thorax	0.011	0.989	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.011	0.989	0.000
C25.4 Endocrine pancreas	0.000	0.990	0.010
Q45 Other congenital malformations of digestive system	0.010	0.990	0.000
Q24.4 Congenital subaortic stenosis	0.010	0.990	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.000	0.990	0.010
F45.8 Other somatoform disorders	0.000	0.990	0.010
Q26 Congenital malformations of great veins	0.010	0.990	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.010	0.990	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.010	0.990	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.010	0.990	0.000
Q00-Q07 Congenital malformations of the nervous system	0.010	0.990	0.000
F20.8 Other schizophrenia	0.000	0.990	0.010
F20.6 Simple schizophrenia	0.000	0.990	0.010
F20.4 Postschizophrenic depression	0.000	0.990	0.010
F20.3 Undifferentiated schizophrenia	0.000	0.990	0.010
F20.1 Hebephrenic schizophrenia	0.000	0.990	0.010
F29 Unspecified nonorganic psychosis	0.000	0.990	0.010
F20.2 Catatonic schizophrenia	0.000	0.990	0.010
Q24.6 Congenital heart block	0.010	0.990	0.000
Q23.3 Congenital mitral insufficiency	0.010	0.990	0.000
C25.7 Other parts of pancreas	0.000	0.990	0.010
Q21 Congenital malformations of cardiac septa	0.010	0.990	0.000
Q25.6 Stenosis of pulmonary artery	0.010	0.990	0.000
Q24.3 Pulmonary infundibular stenosis	0.010	0.990	0.000
Q24.2 Cor triatriatum	0.010	0.990	0.000
Q24.1 Levocardia	0.010	0.990	0.000
Q77.4 Achondroplasia	0.010	0.990	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.010	0.990	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.010	0.990	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.010	0.990	0.000
Q61.9 Cystic kidney disease, unspecified	0.010	0.990	0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.010	0.990	0.000
Q44.4 Choledochal cyst	0.010	0.990	0.000
Q62.5 Duplication of ureter	0.010	0.990	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.010	0.990	0.000
Q44.7 Other congenital malformations of liver	0.009	0.990	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.009	0.990	0.000
Q44.2 Atresia of bile ducts	0.009	0.990	0.000
Q44.1 Other congenital malformations of gallbladder	0.009	0.990	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.009	0.990	0.000
Q75 Other congenital malformations of skull and face bones	0.009	0.990	0.000
Q73 Reduction defects of unspecified limb	0.009	0.990	0.000
Q72 Reduction defects of lower limb	0.009	0.990	0.000
Q71 Reduction defects of upper limb	0.009	0.990	0.000
Q70 Syndactyly	0.009	0.990	0.000
Q69 Polydactyly	0.009	0.990	0.000
Q68 Other congenital musculoskeletal deformities	0.009	0.990	0.000
Q24.5 Malformation of coronary vessels	0.009	0.990	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.009	0.990	0.000
Q25.3 Stenosis of aorta	0.009	0.991	0.000
Q35-Q37 Cleft lip and cleft palate	0.009	0.991	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.009	0.991	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.009	0.991	0.000
Q21.1 Atrial septal defect	0.009	0.991	0.000
Q61.0 Congenital single renal cyst	0.009	0.991	0.000
Q50-Q56 Congenital malformations of genital organs	0.009	0.991	0.000
Q64 Other congenital malformations of urinary system	0.009	0.991	0.000
C25.1 Body of pancreas	0.000	0.991	0.009
Q61.8 Other cystic kidney diseases	0.009	0.991	0.000
Q61.1 Polycystic kidney, infantile type	0.009	0.991	0.000
Q65.9 Congenital deformity of hip, unspecified	0.009	0.991	0.000
Q65.6 Unstable hip	0.009	0.991	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.009	0.991	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.009	0.991	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.009	0.991	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.009	0.991	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.009	0.991	0.000
Q43.3 Congenital malformations of intestinal fixation	0.009	0.991	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.009	0.991	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.009	0.991	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.009	0.991	0.000
Q23.4 Hypoplastic left heart syndrome	0.009	0.991	0.000
Q23.2 Congenital mitral stenosis	0.009	0.991	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.009	0.991	0.000
Q28 Other congenital malformations of circulatory system	0.009	0.991	0.000
Q78 Other osteochondrodysplasias	0.009	0.991	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.009	0.991	0.000
Q45.8 Other specified congenital malformations of digestive system	0.009	0.991	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.009	0.991	0.000
Q25.8 Other congenital malformations of great arteries	0.009	0.991	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.009	0.991	0.000
Q25.5 Atresia of pulmonary artery	0.009	0.991	0.000
Q25.2 Atresia of aorta	0.009	0.991	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.009	0.991	0.000
Q76.1 Klippel-Feil syndrome	0.009	0.991	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.009	0.991	0.000
Q23.1 Congenital insufficiency of aortic valve	0.009	0.991	0.000
C25.9 Pancreas, unspecified	0.000	0.991	0.009
Q40.2 Other specified congenital malformations of stomach	0.009	0.991	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.009	0.991	0.000
Q30 Congenital malformations of nose	0.009	0.991	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.009	0.991	0.000
Q76.5 Cervical rib	0.008	0.991	0.000
Q43.0 Meckel's diverticulum	0.009	0.991	0.000
F25 Schizoaffective disorders	0.000	0.991	0.009
Q24.8 Other specified congenital malformations of heart	0.008	0.991	0.000
T87.2 Complications of other reattached body part	0.008	0.992	0.000
T87.1 Complications of reattached (part of) lower extremity	0.008	0.992	0.000
T87.0 Complications of reattached (part of) upper extremity	0.008	0.992	0.000
C25.8 Overlapping lesion of pancreas	0.000	0.992	0.008
Q67.6 Pectus excavatum	0.008	0.992	0.000
Q03 Congenital hydrocephalus	0.008	0.992	0.000
Q61.4 Renal dysplasia	0.008	0.992	0.000
Q67.5 Congenital deformity of spine	0.008	0.992	0.000
Q62.1 Atresia and stenosis of ureter	0.008	0.992	0.000
Q61.5 Medullary cystic kidney	0.008	0.992	0.000
T87.5 Necrosis of amputation stump	0.008	0.992	0.000
B35.1 Tinea unguium	0.008	0.992	0.000
Q43.7 Persistent cloaca	0.008	0.992	0.000
Q43.6 Congenital fistula of rectum and anus	0.008	0.992	0.000
Q43.5 Ectopic anus	0.008	0.992	0.000
Q43.4 Duplication of intestine	0.008	0.992	0.000
Q43.2 Other congenital functional disorders of colon	0.008	0.992	0.000
C25.2 Tail of pancreas	0.000	0.992	0.008
Q67.8 Other congenital deformities of chest	0.008	0.992	0.000
Q67.7 Pectus carinatum	0.008	0.992	0.000
Q67.3 Plagiocephaly	0.008	0.992	0.000
Q67.2 Dolichocephaly	0.008	0.992	0.000
Q67.1 Compression facies	0.008	0.992	0.000
Q67.0 Facial asymmetry	0.008	0.992	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.008	0.992	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.008	0.992	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.008	0.992	0.000
Q77.6 Chondroectodermal dysplasia	0.008	0.992	0.000
Q77.5 Diastrophic dysplasia	0.008	0.992	0.000
Q77.3 Chondrodysplasia punctata	0.008	0.992	0.000
Q77.2 Short rib syndrome	0.008	0.992	0.000
Q77.1 Thanatophoric short stature	0.008	0.992	0.000
Q77.0 Achondrogenesis	0.008	0.992	0.000
Q74 Other congenital malformations of limb(s)	0.008	0.992	0.000
Q76.0 Spina bifida occulta	0.008	0.992	0.000
Q25.0 Patent ductus arteriosus	0.008	0.992	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.008	0.992	0.000
Q43.1 Hirschsprung's disease	0.008	0.992	0.000
Q40.1 Congenital hiatus hernia	0.008	0.992	0.000
Q66 Congenital deformities of feet	0.008	0.992	0.000
Q27.4 Congenital phlebectasia	0.008	0.992	0.000
Q27.2 Other congenital malformations of renal artery	0.008	0.992	0.000
Q27.1 Congenital renal artery stenosis	0.008	0.992	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.008	0.992	0.000
Q27.3 Peripheral arteriovenous malformation	0.008	0.992	0.000
T80.6 Other serum reactions	0.008	0.992	0.000
T80.5 Anaphylactic shock due to serum	0.008	0.992	0.000
T80.4 Rh incompatibility reaction	0.008	0.992	0.000
T80.3 ABO incompatibility reaction	0.008	0.992	0.000
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.008	0.992	0.000
Q39 Congenital malformations of oesophagus	0.008	0.992	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.008	0.992	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.008	0.992	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.008	0.992	0.000
Q62.8 Other congenital malformations of ureter	0.008	0.992	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.008	0.992	0.000
Q62.6 Malposition of ureter	0.008	0.992	0.000
Q62.4 Agenesis of ureter	0.008	0.992	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.008	0.992	0.000
Q62.0 Congenital hydronephrosis	0.008	0.992	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.008	0.992	0.000
Q76.8 Other congenital malformations of bony thorax	0.008	0.992	0.000
Q76.7 Congenital malformation of sternum	0.008	0.992	0.000
Q76.6 Other congenital malformations of ribs	0.008	0.992	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.008	0.992	0.000
Q76.2 Congenital spondylolisthesis	0.008	0.992	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.008	0.992	0.000
Q34 Other congenital malformations of respiratory system	0.008	0.992	0.000
Q33 Congenital malformations of lung	0.008	0.992	0.000
Q32 Congenital malformations of trachea and bronchus	0.008	0.992	0.000
Q31 Congenital malformations of larynx	0.008	0.992	0.000
Q25.4 Other congenital malformations of aorta	0.008	0.992	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.008	0.992	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.008	0.992	0.000
Q45.2 Congenital pancreatic cyst	0.008	0.992	0.000
Q45.1 Annular pancreas	0.008	0.992	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.008	0.992	0.000
F28 Other nonorganic psychotic disorders	0.000	0.992	0.008
F24 Induced delusional disorder	0.000	0.992	0.008
F21 Schizotypal disorder	0.000	0.992	0.008
C91.1 Chronic lymphocytic leukaemia	0.008	0.992	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.007	0.992	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.007	0.992	0.000
Q20.6 Isomerism of atrial appendages	0.007	0.992	0.000
Q20.5 Discordant atrioventricular connexion	0.007	0.992	0.000
Q20.4 Double inlet ventricle	0.007	0.992	0.000
Q20.3 Discordant ventriculoarterial connexion	0.007	0.992	0.000
Q20.2 Double outlet left ventricle	0.007	0.992	0.000
Q20.1 Double outlet right ventricle	0.007	0.992	0.000
Q20.0 Common arterial trunk	0.007	0.992	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.007	0.992	0.000
Q26.8 Other congenital malformations of great veins	0.007	0.992	0.000
Q26.6 Portal vein-hepatic artery fistula	0.007	0.992	0.000
Q26.5 Anomalous portal venous connexion	0.007	0.992	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.007	0.992	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.007	0.992	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.007	0.992	0.000
Q26.1 Persistent left superior vena cava	0.007	0.992	0.000
Q26.0 Congenital stenosis of vena cava	0.007	0.992	0.000
Q06 Other congenital malformations of spinal cord	0.007	0.992	0.000
Q01 Encephalocele	0.007	0.992	0.000
Q00 Anencephaly and similar malformations	0.007	0.992	0.000
Q02 Microcephaly	0.007	0.992	0.000
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.007	0.992	0.000
C91 Lymphoid leukaemia	0.008	0.992	0.000
Q61.2 Polycystic kidney, adult type	0.008	0.992	0.000
Q04 Other congenital malformations of brain	0.007	0.992	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.007	0.992	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.007	0.992	0.000
Q43.8 Other specified congenital malformations of intestine	0.007	0.992	0.000
Q21.8 Other congenital malformations of cardiac septa	0.007	0.993	0.000
Q28.3 Other malformations of cerebral vessels	0.007	0.993	0.000
C91.0 Acute lymphoblastic leukaemia	0.007	0.993	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.007	0.993	0.000
Q22.5 Ebstein's anomaly	0.007	0.993	0.000
Q78.2 Osteopetrosis	0.007	0.993	0.000
Q96 Turner's syndrome	0.007	0.993	0.000
Q62.2 Congenital megaloureter	0.007	0.993	0.000
Q21.4 Aortopulmonary septal defect	0.007	0.993	0.000
Q21.2 Atrioventricular septal defect	0.007	0.993	0.000
Q07 Other congenital malformations of nervous system	0.007	0.993	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.007	0.993	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.007	0.993	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.007	0.993	0.000
Q22.6 Hypoplastic right heart syndrome	0.007	0.993	0.000
Q22.4 Congenital tricuspid stenosis	0.007	0.993	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.007	0.993	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.007	0.993	0.000
Q22.0 Pulmonary valve atresia	0.007	0.993	0.000
Q05 Spina bifida	0.007	0.993	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.007	0.993	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.007	0.993	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.007	0.993	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.007	0.993	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.007	0.993	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.007	0.993	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.007	0.993	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.007	0.993	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.007	0.993	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.007	0.993	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.007	0.993	0.000
F25.9 Schizoaffective disorder, unspecified	0.000	0.993	0.007
R01.1 Cardiac murmur, unspecified	0.000	0.993	0.007
T87.3 Neuroma of amputation stump	0.007	0.993	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.007	0.993	0.000
Q52 Other congenital malformations of female genitalia	0.007	0.993	0.000
Q03.0 Malformations of aqueduct of Sylvius	0.007	0.993	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.007	0.993	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.007	0.993	0.000
Q68.4 Congenital bowing of tibia and fibula	0.007	0.993	0.000
Q68.3 Congenital bowing of femur	0.007	0.993	0.000
Q68.2 Congenital deformity of knee	0.007	0.993	0.000
Q68.1 Congenital deformity of hand	0.007	0.993	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.007	0.993	0.000
Q69.9 Polydactyly, unspecified	0.007	0.993	0.000
Q69.2 Accessory toe(s)	0.007	0.993	0.000
Q69.1 Accessory thumb(s)	0.007	0.993	0.000
Q69.0 Accessory finger(s)	0.007	0.993	0.000
Q70.9 Syndactyly, unspecified	0.007	0.993	0.000
Q70.4 Polysyndactyly	0.007	0.993	0.000
Q70.3 Webbed toes	0.007	0.993	0.000
Q70.2 Fused toes	0.007	0.993	0.000
Q70.1 Webbed fingers	0.007	0.993	0.000
Q70.0 Fused fingers	0.007	0.993	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.007	0.993	0.000
Q71.8 Other reduction defects of upper limb(s)	0.007	0.993	0.000
Q71.6 Lobster-claw hand	0.007	0.993	0.000
Q71.5 Longitudinal reduction defect of ulna	0.007	0.993	0.000
Q71.4 Longitudinal reduction defect of radius	0.007	0.993	0.000
Q71.3 Congenital absence of hand and finger(s)	0.007	0.993	0.000
Q71.2 Congenital absence of both forearm and hand	0.007	0.993	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.007	0.993	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.007	0.993	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.007	0.993	0.000
Q72.8 Other reduction defects of lower limb(s)	0.007	0.993	0.000
Q72.7 Split foot	0.007	0.993	0.000
Q72.6 Longitudinal reduction defect of fibula	0.007	0.993	0.000
Q72.5 Longitudinal reduction defect of tibia	0.007	0.993	0.000
Q72.4 Longitudinal reduction defect of femur	0.007	0.993	0.000
Q72.3 Congenital absence of foot and toe(s)	0.007	0.993	0.000
Q72.2 Congenital absence of both lower leg and foot	0.007	0.993	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.007	0.993	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.007	0.993	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.007	0.993	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.007	0.993	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.007	0.993	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.007	0.993	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.007	0.993	0.000
Q75.5 Oculomandibular dysostosis	0.007	0.993	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations