TreeWAS – Variant ID: rs4676410

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K51.2 Ulcerative (chronic) proctitis	0.195	0.805	0.000
K51 Ulcerative colitis	0.191	0.809	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.185	0.815	0.000
K51.9 Ulcerative colitis, unspecified	0.183	0.817	0.000
K51.4 Pseudopolyposis of colon	0.162	0.838	0.000
K51.5 Mucosal proctocolitis	0.134	0.866	0.000
K51.8 Other ulcerative colitis	0.130	0.870	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.125	0.875	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.111	0.889	0.000
N64.5 Other signs and symptoms in breast	0.000	0.907	0.093
Z42.1 Follow-up care involving plastic surgery of breast	0.000	0.957	0.043
Z42 Follow-up care involving plastic surgery	0.000	0.967	0.033
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.000	0.969	0.031
Z42.4 Follow-up care involving plastic surgery of lower extremity	0.000	0.972	0.027
Z42.0 Follow-up care involving plastic surgery of head and neck	0.000	0.973	0.027
Z63.7 Other stressful life events affecting family and household	0.027	0.973	0.000
Z63 Other problems related to primary support group, including family circumstances	0.027	0.973	0.000
Z63.4 Disappearance and death of family member	0.026	0.974	0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.000	0.976	0.024
Z63.0 Problems in relationship with spouse or partner	0.022	0.978	0.000
Z63.5 Disruption of family by separation and divorce	0.022	0.978	0.000
Z63.6 Dependent relative needing care at home	0.022	0.978	0.000
Z42.9 Follow-up care involving plastic surgery, unspecified	0.000	0.979	0.021
Z42.8 Follow-up care involving plastic surgery of other body part	0.000	0.979	0.021
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.020	0.980	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.020	0.980	0.000
Z63.9 Problem related to primary support group, unspecified	0.019	0.980	0.000
Z63.3 Absence of family member	0.019	0.980	0.000
Z63.2 Inadequate family support	0.019	0.980	0.000
Z63.1 Problems in relationship with parents and in-laws	0.019	0.980	0.000
I05.9 Mitral valve disease, unspecified	0.000	0.981	0.019
Z63.8 Other specified problems related to primary support group	0.019	0.981	0.000
T42.0 Hydantoin derivatives	0.018	0.982	0.000
T42.4 Benzodiazepines	0.018	0.982	0.000
Y86 Sequelae of other accidents	0.000	0.983	0.017
K50-K52 Noninfective enteritis and colitis	0.016	0.984	0.000
T42.1 Iminostilbenes	0.016	0.984	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.015	0.985	0.000
I05 Rheumatic mitral valve diseases	0.000	0.985	0.015
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.014	0.986	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.014	0.986	0.000
T42.3 Barbiturates	0.014	0.986	0.000
T42.2 Succinimides and oxazolidinediones	0.014	0.986	0.000
I05.2 Mitral stenosis with insufficiency	0.000	0.986	0.014
I05.0 Mitral stenosis	0.000	0.987	0.013
N64 Other disorders of breast	0.000	0.989	0.011
I05.8 Other mitral valve diseases	0.000	0.989	0.011
Q21.1 Atrial septal defect	0.010	0.990	0.000
I05.1 Rheumatic mitral insufficiency	0.000	0.990	0.010
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.010	0.990	0.000
Z98.0 Intestinal bypass and anastomosis status	0.009	0.991	0.000
Q21 Congenital malformations of cardiac septa	0.008	0.992	0.000
Z61 Problems related to negative life events in childhood	0.008	0.992	0.000
N64.3 Galactorrhoea not associated with childbirth	0.000	0.992	0.008
N64.2 Atrophy of breast	0.000	0.992	0.008
N64.0 Fissure and fistula of nipple	0.000	0.992	0.008
Z65 Problems related to other psychosocial circumstances	0.008	0.992	0.000
N64.4 Mastodynia	0.000	0.992	0.008
T36-T50 Poisoning by drugs, medicaments and biological substances	0.008	0.992	0.000
N64.8 Other specified disorders of breast	0.000	0.992	0.008
Q21.0 Ventricular septal defect	0.008	0.992	0.000
Z56 Problems related to employment and unemployment	0.007	0.993	0.000
Z57 Occupational exposure to risk-factors	0.007	0.993	0.000
Z59 Problems related to housing and economic circumstances	0.007	0.993	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.007	0.993	0.000
Z62 Other problems related to upbringing	0.007	0.993	0.000
Z55 Problems related to education and literacy	0.007	0.993	0.000
Z65.9 Problem related to unspecified psychosocial circumstances	0.007	0.993	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.007	0.993	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.007	0.993	0.000
Z61.6 Problems related to alleged physical abuse of child	0.007	0.993	0.000
T45.0 Antiallergic and antiemetic drugs	0.007	0.993	0.000
Z64 Problems related to certain psychosocial circumstances	0.007	0.993	0.000
Z57.3 Occupational exposure to other air contaminants	0.007	0.993	0.000
Q21.3 Tetralogy of Fallot	0.007	0.993	0.000
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.007	0.993	0.000
T40.4 Other synthetic narcotics	0.006	0.993	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.006	0.994	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.006	0.994	0.000
T40.6 Other and unspecified narcotics	0.006	0.994	0.000
Z59.8 Other problems relating to housing and economic circumstances	0.006	0.994	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.006	0.994	0.000
Q21.8 Other congenital malformations of cardiac septa	0.006	0.994	0.000
Q21.4 Aortopulmonary septal defect	0.006	0.994	0.000
Q21.2 Atrioventricular septal defect	0.006	0.994	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.000	0.994	0.006
Z61.9 Negative life events in childhood, unspecified	0.006	0.994	0.000
Z61.8 Other negative life events in childhood	0.006	0.994	0.000
Z61.7 Personal frightening experience in childhood	0.006	0.994	0.000
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.006	0.994	0.000
Z61.3 Events resulting in loss of self-esteem in childhood	0.006	0.994	0.000
Z61.2 Altered pattern of family relationships in childhood	0.006	0.994	0.000
Z61.1 Removal from home in childhood	0.006	0.994	0.000
Z61.0 Loss of love relationship in childhood	0.006	0.994	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.006	0.994	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.006	0.994	0.000
T39.1 4-Aminophenol derivatives	0.006	0.994	0.000
C67.2 Lateral wall of bladder	0.006	0.994	0.000
Z65.5 Exposure to disaster, war and other hostilities	0.006	0.994	0.000
Z65.4 Victim of crime and terrorism	0.006	0.994	0.000
Z65.3 Problems related to other legal circumstances	0.006	0.994	0.000
Z65.2 Problems related to release from prison	0.006	0.994	0.000
Z65.1 Imprisonment and other incarceration	0.006	0.994	0.000
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.006	0.994	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.006	0.994	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.006	0.994	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.006	0.994	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.006	0.994	0.000
T38.1 Thyroid hormones and substitutes	0.006	0.994	0.000
Z65.8 Other specified problems related to psychosocial circumstances	0.006	0.994	0.000
Z56.3 Stressful work schedule	0.006	0.994	0.000
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.006	0.994	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.006	0.994	0.000
T45.2 Vitamins, not elsewhere classified	0.006	0.994	0.000
J43.9 Emphysema, unspecified	0.000	0.994	0.006
T36 Poisoning by systemic antibiotics	0.006	0.994	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.006	0.994	0.000
Z57.8 Occupational exposure to other risk-factors	0.006	0.994	0.000
Z57.2 Occupational exposure to dust	0.006	0.994	0.000
Z56.7 Other and unspecified problems related to employment	0.005	0.994	0.000
Z56.5 Uncongenial work	0.005	0.994	0.000
Z56.4 Discord with boss and workmates	0.005	0.994	0.000
Z56.2 Threat of job loss	0.005	0.994	0.000
Z56.1 Change of job	0.005	0.994	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.005	0.994	0.000
Z57.7 Occupational exposure to vibration	0.005	0.994	0.000
Z57.6 Occupational exposure to extreme temperature	0.005	0.994	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.005	0.994	0.000
Z57.1 Occupational exposure to radiation	0.005	0.994	0.000
Z57.0 Occupational exposure to noise	0.005	0.994	0.000
Z56.0 Unemployment, unspecified	0.005	0.994	0.000
Z59.7 Insufficient social insurance and welfare support	0.005	0.994	0.000
Z59.6 Low income	0.005	0.994	0.000
Z59.5 Extreme poverty	0.005	0.994	0.000
Z59.4 Lack of adequate food	0.005	0.994	0.000
Z59.3 Problems related to living in residential institution	0.005	0.994	0.000
Z59.2 Discord with neighbours, lodgers and landlord	0.005	0.994	0.000
Z59.1 Inadequate housing	0.005	0.994	0.000
T45.5 Anticoagulants	0.005	0.994	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.005	0.994	0.000
T45.8 Other primarily systemic and haematological agents	0.005	0.994	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.005	0.994	0.000
T45.6 Fibrinolysis-affecting drugs	0.005	0.994	0.000
T45.4 Iron and its compounds	0.005	0.994	0.000
T45.3 Enzymes, not elsewhere classified	0.005	0.994	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.005	0.994	0.000
Z56.6 Other physical and mental strain related to work	0.005	0.994	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.005	0.995	0.000
Z55.9 Problems relating to education and literacy, unspecified	0.005	0.995	0.000
Z55.8 Other problems relating to education and literacy	0.005	0.995	0.000
Z55.4 Educational maladjustment and discord with teachers and classmates	0.005	0.995	0.000
Z55.3 Underachievement in school	0.005	0.995	0.000
Z55.2 Failed examinations	0.005	0.995	0.000
Z55.1 Schooling unavailable and unattainable	0.005	0.995	0.000
Z55.0 Illiteracy and low-level literacy	0.005	0.995	0.000
Z62.9 Problem related to upbringing, unspecified	0.005	0.995	0.000
Z62.8 Other specified problems related to upbringing	0.005	0.995	0.000
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.005	0.995	0.000
Z62.5 Other problems related to neglect in upbringing	0.005	0.995	0.000
Z62.4 Emotional neglect of child	0.005	0.995	0.000
Z62.3 Hostility towards and scapegoating of child	0.005	0.995	0.000
Z62.2 Institutional upbringing	0.005	0.995	0.000
Z62.1 Parental overprotection	0.005	0.995	0.000
Z62.0 Inadequate parental supervision and control	0.005	0.995	0.000
I05-I09 Chronic rheumatic heart diseases	0.000	0.995	0.005
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.005	0.995	0.000
T40.8 Lysergide [LSD]	0.005	0.995	0.000
T40.7 Cannabis (derivatives)	0.005	0.995	0.000
T40.5 Cocaine	0.005	0.995	0.000
T40.3 Methadone	0.005	0.995	0.000
T40.1 Heroin	0.005	0.995	0.000
T40.0 Opium	0.005	0.995	0.000
T38.9 Other and unspecified hormone antagonists	0.005	0.995	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.005	0.995	0.000
T38.7 Androgens and anabolic congeners	0.005	0.995	0.000
T38.5 Other oestrogens and progestogens	0.005	0.995	0.000
T38.4 Oral contraceptives	0.005	0.995	0.000
T38.2 Antithyroid drugs	0.005	0.995	0.000
T38.0 Glucocorticoids and synthetic analogues	0.005	0.995	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.005	0.995	0.000
Z58 Problems related to physical environment	0.005	0.995	0.000
Z64.4 Discord with counsellors	0.005	0.995	0.000
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.005	0.995	0.000
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.005	0.995	0.000
Z64.1 Problems related to multiparity	0.005	0.995	0.000
T50.8 Diagnostic agents	0.005	0.995	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.000	0.995	0.005
I09 Other rheumatic heart diseases	0.000	0.995	0.005
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.000	0.995	0.005
Q20-Q28 Congenital malformations of the circulatory system	0.005	0.995	0.000
T39.4 Antirheumatics, not elsewhere classified	0.005	0.995	0.000
T39.2 Pyrazolone derivatives	0.005	0.995	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.005	0.995	0.000
T49.9 Topical agent, unspecified	0.005	0.995	0.000
T49.8 Other topical agents	0.005	0.995	0.000
T49.7 Dental drugs, topically applied	0.005	0.995	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.005	0.995	0.000
T49.5 Ophthalmological drugs and preparations	0.005	0.995	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.005	0.995	0.000
T49.3 Emollients, demulcents and protectants	0.005	0.995	0.000
T49.2 Local astringents and local detergents	0.005	0.995	0.000
T49.1 Antipruritics	0.005	0.995	0.000
Q61.3 Polycystic kidney, unspecified	0.000	0.995	0.005
I09.9 Rheumatic heart disease, unspecified	0.000	0.995	0.005
Z64.0 Problems related to unwanted pregnancy	0.005	0.995	0.000
Q28 Other congenital malformations of circulatory system	0.005	0.995	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.004	0.995	0.000
T48.5 Anti-common-cold drugs	0.004	0.995	0.000
T48.4 Expectorants	0.004	0.995	0.000
T48.3 Antitussives	0.004	0.995	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.004	0.995	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.004	0.995	0.000
T48.0 Oxytocic drugs	0.004	0.995	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.005	0.995	0.000
T50.7 Analeptics and opioid receptor antagonists	0.004	0.995	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.004	0.995	0.000
T50.5 Appetite depressants	0.004	0.995	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.004	0.995	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.004	0.995	0.000
T50.1 Loop [high-ceiling] diuretics	0.004	0.995	0.000
T50.0 Mineralocorticoids and their antagonists	0.004	0.995	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.005	0.995	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.004	0.995	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.004	0.995	0.000
T37.5 Antiviral drugs	0.004	0.995	0.000
T37.4 Anthelminthics	0.004	0.995	0.000
T37.3 Other antiprotozoal drugs	0.004	0.995	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.004	0.995	0.000
T37.1 Antimycobacterial drugs	0.004	0.995	0.000
T37.0 Sulphonamides	0.004	0.995	0.000
T41.5 Therapeutic gases	0.004	0.995	0.000
T41.4 Anaesthetic, unspecified	0.004	0.995	0.000
T41.3 Local anaesthetics	0.004	0.995	0.000
T41.2 Other and unspecified general anaesthetics	0.004	0.995	0.000
T41.1 Intravenous anaesthetics	0.004	0.995	0.000
T41.0 Inhaled anaesthetics	0.004	0.995	0.000
T50.4 Drugs affecting uric acid metabolism	0.004	0.995	0.000
S62.61 Fracture of other finger (open)	0.000	0.995	0.005
K50 Crohn's disease [regional enteritis]	0.005	0.995	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.004	0.995	0.000
C67 Malignant neoplasm of bladder	0.004	0.996	0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.004	0.996	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.004	0.996	0.000
T36.9 Systemic antibiotic, unspecified	0.004	0.996	0.000
T36.8 Other systemic antibiotics	0.004	0.996	0.000
T36.7 Antifungal antibiotics, systemically used	0.004	0.996	0.000
T36.6 Rifamycins	0.004	0.996	0.000
T36.5 Aminoglycosides	0.004	0.996	0.000
T36.4 Tetracyclines	0.004	0.996	0.000
T36.3 Macrolides	0.004	0.996	0.000
T36.2 Chloramphenicol group	0.004	0.996	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.004	0.996	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.000	0.996	0.004
Z59.0 Homelessness	0.004	0.996	0.000
N64.1 Fat necrosis of breast	0.000	0.996	0.004
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.004	0.996	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.004	0.996	0.000
T47.7 Emetics	0.004	0.996	0.000
T47.6 Antidiarrhoeal drugs	0.004	0.996	0.000
T47.5 Digestants	0.004	0.996	0.000
T47.4 Other laxatives	0.004	0.996	0.000
T47.3 Saline and osmotic laxatives	0.004	0.996	0.000
T47.2 Stimulant laxatives	0.004	0.996	0.000
T47.0 Histamine H(2)-receptor antagonists	0.004	0.996	0.000
Z60 Problems related to social environment	0.004	0.996	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.000	0.996	0.004
C67.1 Dome of bladder	0.004	0.996	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.000	0.996	0.004
I07 Rheumatic tricuspid valve diseases	0.000	0.996	0.004
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.000	0.996	0.004
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.000	0.996	0.004
T50.9 Other and unspecified drugs, medicaments and biological substances	0.004	0.996	0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.004	0.996	0.000
Z58.9 Problem related to physical environment, unspecified	0.004	0.996	0.000
Z58.6 Inadequate drinking-water supply	0.004	0.996	0.000
Z58.5 Exposure to other pollution	0.004	0.996	0.000
Z58.4 Exposure to radiation	0.004	0.996	0.000
Z58.3 Exposure to soil pollution	0.004	0.996	0.000
Z58.2 Exposure to water pollution	0.004	0.996	0.000
Z58.0 Exposure to noise	0.004	0.996	0.000
I06 Rheumatic aortic valve diseases	0.000	0.996	0.004
C67.4 Posterior wall of bladder	0.004	0.996	0.000
F80.1 Expressive language disorder	0.004	0.996	0.000
C67.3 Anterior wall of bladder	0.004	0.996	0.000
Z58.7 Exposure to tobacco smoke	0.004	0.996	0.000
C67.5 Bladder neck	0.004	0.996	0.000
T36.0 Penicillins	0.004	0.996	0.000
Q61 Cystic kidney disease	0.000	0.996	0.004
W44.0 Home	0.004	0.996	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.000	0.996	0.004
I09.8 Other specified rheumatic heart diseases	0.000	0.996	0.004
I09.2 Chronic rheumatic pericarditis	0.000	0.996	0.004
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.996	0.004
I09.0 Rheumatic myocarditis	0.000	0.996	0.004
Q28.3 Other malformations of cerebral vessels	0.004	0.996	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.000	0.996	0.004
Q26 Congenital malformations of great veins	0.004	0.996	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.004	0.996	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.004	0.996	0.000
Q61.2 Polycystic kidney, adult type	0.000	0.996	0.004
Q24 Other congenital malformations of heart	0.004	0.996	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.004	0.996	0.000
Q25 Congenital malformations of great arteries	0.004	0.996	0.000
T40.2 Other opioids	0.004	0.996	0.000
Y88 Sequelae of surgical and medical care as external cause	0.000	0.996	0.004
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.000	0.996	0.004
Q28.9 Congenital malformation of circulatory system, unspecified	0.004	0.996	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.004	0.996	0.000
Q28.1 Other malformations of precerebral vessels	0.004	0.996	0.000
Q23 Congenital malformations of aortic and mitral valves	0.004	0.996	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.004	0.996	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.000	0.996	0.004
Q61.5 Medullary cystic kidney	0.000	0.996	0.004
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.000	0.996	0.004
T82.3 Mechanical complication of other vascular grafts	0.004	0.996	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.003	0.996	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.996	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.996	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.996	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.996	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.996	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.003	0.996	0.000
T44.0 Anticholinesterase agents	0.003	0.996	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.996	0.004
C67.7 Urachus	0.003	0.997	0.000
Q27 Other congenital malformations of peripheral vascular system	0.003	0.997	0.000
C67.6 Ureteric orifice	0.003	0.997	0.000
S01.5 Open wound of lip and oral cavity	0.000	0.997	0.003
Z57.5 Occupational exposure to toxic agents in other industries	0.003	0.997	0.000
Z58.8 Other problems related to physical environment	0.003	0.997	0.000
N64.9 Disorder of breast, unspecified	0.001	0.997	0.003
D36.7 Other specified sites	0.003	0.997	0.000
Z60.5 Target of perceived adverse discrimination and persecution	0.003	0.997	0.000
Z60.4 Social exclusion and rejection	0.003	0.997	0.000
Z60.3 Acculturation difficulty	0.003	0.997	0.000
Z60.1 Atypical parenting situation	0.003	0.997	0.000
Z60.0 Problems of adjustment to life-cycle transitions	0.003	0.997	0.000
C67.0 Trigone of bladder	0.003	0.997	0.000
Z60.9 Problem related to social environment, unspecified	0.003	0.997	0.000
I07.9 Tricuspid valve disease, unspecified	0.000	0.997	0.003
I07.8 Other tricuspid valve diseases	0.000	0.997	0.003
I07.2 Tricuspid stenosis with insufficiency	0.000	0.997	0.003
I07.0 Tricuspid stenosis	0.000	0.997	0.003
Q61.9 Cystic kidney disease, unspecified	0.000	0.997	0.003
I07.1 Tricuspid insufficiency	0.000	0.997	0.003
Z58.1 Exposure to air pollution	0.003	0.997	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.997	0.003
I06.8 Other rheumatic aortic valve diseases	0.000	0.997	0.003
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.997	0.003
I06.0 Rheumatic aortic stenosis	0.000	0.997	0.003
Y89 Sequelae of other external causes	0.000	0.997	0.003
Z60.8 Other problems related to social environment	0.003	0.997	0.000
C67.8 Overlapping lesion of bladder	0.003	0.997	0.000
Q25.4 Other congenital malformations of aorta	0.003	0.997	0.000
Q25.0 Patent ductus arteriosus	0.003	0.997	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.003	0.997	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.003	0.997	0.000
Q61.8 Other cystic kidney diseases	0.000	0.997	0.003
Q61.4 Renal dysplasia	0.000	0.997	0.003
Q61.1 Polycystic kidney, infantile type	0.000	0.997	0.003
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.000	0.997	0.003
H54.7 Unspecified visual loss	0.003	0.997	0.000
I06.1 Rheumatic aortic insufficiency	0.000	0.997	0.003
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.003	0.997	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
Q20.6 Isomerism of atrial appendages	0.003	0.997	0.000
Q20.5 Discordant atrioventricular connexion	0.003	0.997	0.000
Q20.4 Double inlet ventricle	0.003	0.997	0.000
Q20.3 Discordant ventriculoarterial connexion	0.003	0.997	0.000
Q20.2 Double outlet left ventricle	0.003	0.997	0.000
Q20.1 Double outlet right ventricle	0.003	0.997	0.000
Q20.0 Common arterial trunk	0.003	0.997	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.003	0.997	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.003	0.997	0.000
Q22.6 Hypoplastic right heart syndrome	0.003	0.997	0.000
Q22.5 Ebstein's anomaly	0.003	0.997	0.000
Q22.4 Congenital tricuspid stenosis	0.003	0.997	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.003	0.997	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.003	0.997	0.000
Q22.1 Congenital pulmonary valve stenosis	0.003	0.997	0.000
Q22.0 Pulmonary valve atresia	0.003	0.997	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.003	0.997	0.000
Q26.8 Other congenital malformations of great veins	0.003	0.997	0.000
Q26.6 Portal vein-hepatic artery fistula	0.003	0.997	0.000
Q26.5 Anomalous portal venous connexion	0.003	0.997	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.003	0.997	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.003	0.997	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.003	0.997	0.000
Q26.1 Persistent left superior vena cava	0.003	0.997	0.000
Q26.0 Congenital stenosis of vena cava	0.003	0.997	0.000
Q24.6 Congenital heart block	0.003	0.997	0.000
Q24.4 Congenital subaortic stenosis	0.003	0.997	0.000
Q24.3 Pulmonary infundibular stenosis	0.003	0.997	0.000
Q24.2 Cor triatriatum	0.003	0.997	0.000
Q24.1 Levocardia	0.003	0.997	0.000
Q24.0 Dextrocardia	0.003	0.997	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.997	0.003
Q24.8 Other specified congenital malformations of heart	0.003	0.997	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.003	0.997	0.000
Q25.8 Other congenital malformations of great arteries	0.003	0.997	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.003	0.997	0.000
Q25.6 Stenosis of pulmonary artery	0.003	0.997	0.000
Q25.5 Atresia of pulmonary artery	0.003	0.997	0.000
Q25.3 Stenosis of aorta	0.003	0.997	0.000
Q25.2 Atresia of aorta	0.003	0.997	0.000
F80 Specific developmental disorders of speech and language	0.003	0.997	0.000
H47.3 Other disorders of optic disk	0.000	0.997	0.003
Q23.0 Congenital stenosis of aortic valve	0.003	0.997	0.000
Y88.2 Sequelae of adverse incidents associated with medical devices in diagnostic and therapeutic use	0.000	0.997	0.003
Y88.0 Sequelae of adverse effects caused by drugs, medicaments and biological substances in therapeutic use	0.000	0.997	0.003
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.003	0.997	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.003	0.997	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.003	0.997	0.000
Q23.4 Hypoplastic left heart syndrome	0.003	0.997	0.000
Q23.3 Congenital mitral insufficiency	0.003	0.997	0.000
Q23.2 Congenital mitral stenosis	0.003	0.997	0.000
R27.0 Ataxia, unspecified	0.003	0.997	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.002	0.997	0.001
J43 Emphysema	0.000	0.997	0.003
Q24.5 Malformation of coronary vessels	0.003	0.997	0.000
Q27.3 Peripheral arteriovenous malformation	0.003	0.997	0.000
I77.6 Arteritis, unspecified	0.000	0.997	0.003
O90.1 Disruption of perineal obstetric wound	0.003	0.997	0.000
Q27.4 Congenital phlebectasia	0.003	0.997	0.000
Q27.2 Other congenital malformations of renal artery	0.003	0.997	0.000
Q27.1 Congenital renal artery stenosis	0.003	0.997	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.003	0.997	0.000
K50.9 Crohn's disease, unspecified	0.003	0.997	0.000
Q61.0 Congenital single renal cyst	0.000	0.997	0.003
T39.0 Salicylates	0.003	0.997	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.003	0.997	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.002	0.997	0.000
D36.0 Lymph nodes	0.003	0.997	0.000
F80.2 Receptive language disorder	0.003	0.997	0.000
D36 Benign neoplasm of other and unspecified sites	0.003	0.997	0.000
Q23.1 Congenital insufficiency of aortic valve	0.003	0.997	0.000
Q25.1 Coarctation of aorta	0.002	0.997	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.997	0.000
Y88.1 Sequelae of misadventures to patients during surgical and medical procedures	0.000	0.997	0.002
K50.1 Crohn's disease of large intestine	0.003	0.997	0.000
Y89.1 Sequelae of war operations	0.000	0.997	0.002
Y89.0 Sequelae of legal intervention	0.000	0.997	0.002
K50.8 Other Crohn's disease	0.002	0.997	0.000
O90 Complications of the puerperium, not elsewhere classified	0.003	0.997	0.000
Y85 Sequelae of transport accidents	0.000	0.997	0.002
K50.0 Crohn's disease of small intestine	0.003	0.997	0.000
J43.2 Centrilobular emphysema	0.000	0.997	0.002
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.000	0.997	0.002
N60-N64 Disorders of breast	0.000	0.998	0.002
L27.1 Localised skin eruption due to drugs and medicaments	0.002	0.998	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.002	0.998	0.000
F80.9 Developmental disorder of speech and language, unspecified	0.002	0.998	0.000
F80.8 Other developmental disorders of speech and language	0.002	0.998	0.000
F80.3 Acquired aphasia with epilepsy [Landau-Kleffner]	0.002	0.998	0.000
F80.0 Specific speech articulation disorder	0.002	0.998	0.000
D36.9 Benign neoplasm of unspecified site	0.002	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.001
T46.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.001
T46.7 Peripheral vasodilators	0.002	0.998	0.001
T46.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.001
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.001
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.001
Y89.9 Sequelae of unspecified external cause	0.000	0.998	0.002
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.998	0.002
J43.1 Panlobular emphysema	0.000	0.998	0.002
J43.0 MacLeod's syndrome	0.000	0.998	0.002
J18.9 Pneumonia, unspecified	0.000	0.998	0.002
J43.8 Other emphysema	0.000	0.998	0.002
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.002	0.998	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.000	0.998	0.002
D36.1 Peripheral nerves and autonomic nervous system	0.002	0.998	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.002	0.998	0.000
O90.2 Haematoma of obstetric wound	0.002	0.998	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.002	0.998	0.000
M62.88 Other specified disorders of muscle (Other)	0.000	0.998	0.002
K52 Other non-infective gastro-enteritis and colitis	0.002	0.998	0.000
M65 Synovitis and tenosynovitis	0.000	0.998	0.002
N62 Hypertrophy of breast	0.000	0.998	0.002
O85 Puerperal sepsis	0.002	0.998	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.000	0.998	0.002
H43.8 Other disorders of vitreous body	0.000	0.998	0.002
O90.8 Other complications of the puerperium, not elsewhere classified	0.002	0.998	0.000
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.002	0.998	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.998	0.002
L30.9 Dermatitis, unspecified	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.001
H54.9 Unspecified visual impairment (binocular)	0.002	0.998	0.000
M35.3 Polymyalgia rheumatica	0.002	0.998	0.000
L27 Dermatitis due to substances taken internally	0.002	0.998	0.000
F43.1 Posttraumatic stress disorder	0.002	0.998	0.000
T46.1 Calcium-channel blockers	0.002	0.998	0.001
H54 Blindness and low vision	0.002	0.998	0.000
O12.1 Gestational proteinuria	0.002	0.998	0.000
I87 Other disorders of veins	0.002	0.998	0.000
O90.9 Complication of the puerperium, unspecified	0.002	0.998	0.000
O90.5 Postpartum thyroiditis	0.002	0.998	0.000
O90.4 Postpartum acute renal failure	0.002	0.998	0.000
O90.3 Cardiomyopathy in the puerperium	0.002	0.998	0.000
O90.0 Disruption of Caesarean section wound	0.002	0.998	0.000
R27 Other lack of coordination	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations