TreeWAS – Variant ID: rs4703129

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K82.8 Other specified diseases of gallbladder	0.395	0.605	0.000
K82 Other diseases of gallbladder	0.070	0.930	0.000
K82.4 Cholesterolosis of gallbladder	0.062	0.938	0.000
K82.1 Hydrops of gallbladder	0.054	0.946	0.000
K82.0 Obstruction of gallbladder	0.043	0.957	0.000
K82.3 Fistula of gallbladder	0.041	0.958	0.000
K82.2 Perforation of gallbladder	0.035	0.965	0.000
K82.9 Disease of gallbladder, unspecified	0.017	0.982	0.001
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.014	0.986	0.000
M20.5 Other deformities of toe(s) (acquired)	0.014	0.986	0.000
Q76.0 Spina bifida occulta	0.012	0.988	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.000	0.989	0.011
Q76 Congenital malformations of spine and bony thorax	0.010	0.990	0.000
Z88.3 Personal history of allergy to other anti-infective agents	0.009	0.991	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.009	0.991	0.000
Q65 Congenital deformities of hip	0.009	0.991	0.000
I74.5 Embolism and thrombosis of iliac artery	0.000	0.991	0.009
M20 Acquired deformities of fingers and toes	0.009	0.991	0.000
Q76.5 Cervical rib	0.009	0.991	0.000
Q65.8 Other congenital deformities of hip	0.009	0.991	0.000
M25.9 Joint disorder, unspecified	0.000	0.992	0.008
Q78 Other osteochondrodysplasias	0.008	0.992	0.000
Q74 Other congenital malformations of limb(s)	0.008	0.992	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.008	0.992	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.008	0.992	0.000
Q66 Congenital deformities of feet	0.008	0.992	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.007	0.992	0.000
Q76.8 Other congenital malformations of bony thorax	0.007	0.992	0.000
Q76.7 Congenital malformation of sternum	0.007	0.992	0.000
Q76.6 Other congenital malformations of ribs	0.007	0.992	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.007	0.992	0.000
Q76.2 Congenital spondylolisthesis	0.007	0.992	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.007	0.992	0.000
Q76.1 Klippel-Feil syndrome	0.007	0.993	0.000
M20.4 Other hammer toe(s) (acquired)	0.007	0.993	0.000
K86.2 Cyst of pancreas	0.000	0.993	0.007
Q70 Syndactyly	0.007	0.993	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.000	0.993	0.007
M25.94 Joint disorder, unspecified (Hand)	0.000	0.993	0.007
Q75 Other congenital malformations of skull and face bones	0.007	0.993	0.000
Q73 Reduction defects of unspecified limb	0.007	0.993	0.000
Q72 Reduction defects of lower limb	0.007	0.993	0.000
Q71 Reduction defects of upper limb	0.007	0.993	0.000
Q69 Polydactyly	0.007	0.993	0.000
Q66.3 Other congenital varus deformities of feet	0.007	0.993	0.000
Q78.0 Osteogenesis imperfecta	0.007	0.993	0.000
M20.2 Hallux rigidus	0.007	0.993	0.000
D06.9 Cervix, unspecified	0.007	0.993	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.007	0.993	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.007	0.993	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.000	0.993	0.007
Q65.9 Congenital deformity of hip, unspecified	0.006	0.993	0.000
Q65.6 Unstable hip	0.006	0.993	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.006	0.993	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.006	0.993	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.006	0.993	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.006	0.993	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.006	0.993	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.006	0.993	0.000
L60.0 Ingrowing nail	0.007	0.993	0.000
Q68 Other congenital musculoskeletal deformities	0.006	0.993	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.006	0.994	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.000	0.994	0.006
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.006	0.994	0.000
M20.3 Other deformity of hallux (acquired)	0.006	0.994	0.000
Q66.7 Pes cavus	0.006	0.994	0.000
M20.0 Deformity of finger(s)	0.006	0.994	0.000
Q77.4 Achondroplasia	0.006	0.994	0.000
M25.98 Joint disorder, unspecified (Other)	0.000	0.994	0.006
M25.92 Joint disorder, unspecified (Upper arm)	0.000	0.994	0.006
M25.90 Joint disorder, unspecified (Multiple sites)	0.000	0.994	0.006
T51.0 Ethanol	0.000	0.994	0.006
Q74.1 Congenital malformation of knee	0.006	0.994	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.006	0.994	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.006	0.994	0.000
Q66.2 Metatarsus varus	0.006	0.994	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.000	0.994	0.006
M25.93 Joint disorder, unspecified (Forearm)	0.000	0.994	0.006
Q78.9 Osteochondrodysplasia, unspecified	0.006	0.994	0.000
Q78.8 Other specified osteochondrodysplasias	0.006	0.994	0.000
Q78.6 Multiple congenital exostoses	0.006	0.994	0.000
Q78.5 Metaphyseal dysplasia	0.006	0.994	0.000
Q78.4 Enchondromatosis	0.006	0.994	0.000
Q78.3 Progressive diaphyseal dysplasia	0.006	0.994	0.000
Q78.2 Osteopetrosis	0.006	0.994	0.000
Q78.1 Polyostotic fibrous dysplasia	0.006	0.994	0.000
I08 Multiple valve diseases	0.006	0.994	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.994	0.006
Q74.9 Unspecified congenital malformation of limb(s)	0.006	0.994	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.006	0.994	0.000
Q74.3 Arthrogryposis multiplex congenita	0.006	0.994	0.000
Q66.5 Congenital pes planus	0.006	0.994	0.000
Q66.4 Talipes calcaneovalgus	0.006	0.994	0.000
Q66.1 Talipes calcaneovarus	0.006	0.994	0.000
Q66.0 Talipes equinovarus	0.006	0.994	0.000
Q66.9 Congenital deformity of feet, unspecified	0.006	0.994	0.000
E16.2 Hypoglycaemia, unspecified	0.000	0.994	0.006
Q70.3 Webbed toes	0.006	0.994	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.005	0.994	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.005	0.994	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.005	0.994	0.000
Q77.6 Chondroectodermal dysplasia	0.005	0.994	0.000
Q77.5 Diastrophic dysplasia	0.005	0.994	0.000
Q77.3 Chondrodysplasia punctata	0.005	0.994	0.000
Q77.2 Short rib syndrome	0.005	0.994	0.000
Q77.1 Thanatophoric short stature	0.005	0.994	0.000
Q77.0 Achondrogenesis	0.005	0.994	0.000
M20.1 Hallux valgus (acquired)	0.006	0.994	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.005	0.994	0.000
Q66.6 Other congenital valgus deformities of feet	0.005	0.995	0.000
Q70.9 Syndactyly, unspecified	0.005	0.995	0.000
Q70.4 Polysyndactyly	0.005	0.995	0.000
Q70.2 Fused toes	0.005	0.995	0.000
Q70.1 Webbed fingers	0.005	0.995	0.000
Q70.0 Fused fingers	0.005	0.995	0.000
Q69.9 Polydactyly, unspecified	0.005	0.995	0.000
Q69.2 Accessory toe(s)	0.005	0.995	0.000
Q69.1 Accessory thumb(s)	0.005	0.995	0.000
Q69.0 Accessory finger(s)	0.005	0.995	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.005	0.995	0.000
Q71.8 Other reduction defects of upper limb(s)	0.005	0.995	0.000
Q71.6 Lobster-claw hand	0.005	0.995	0.000
Q71.5 Longitudinal reduction defect of ulna	0.005	0.995	0.000
Q71.4 Longitudinal reduction defect of radius	0.005	0.995	0.000
Q71.3 Congenital absence of hand and finger(s)	0.005	0.995	0.000
Q71.2 Congenital absence of both forearm and hand	0.005	0.995	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.005	0.995	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.005	0.995	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.005	0.995	0.000
Q72.8 Other reduction defects of lower limb(s)	0.005	0.995	0.000
Q72.7 Split foot	0.005	0.995	0.000
Q72.6 Longitudinal reduction defect of fibula	0.005	0.995	0.000
Q72.5 Longitudinal reduction defect of tibia	0.005	0.995	0.000
Q72.4 Longitudinal reduction defect of femur	0.005	0.995	0.000
Q72.3 Congenital absence of foot and toe(s)	0.005	0.995	0.000
Q72.2 Congenital absence of both lower leg and foot	0.005	0.995	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.005	0.995	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.005	0.995	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.005	0.995	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.005	0.995	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.005	0.995	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.005	0.995	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.005	0.995	0.000
Q75.5 Oculomandibular dysostosis	0.005	0.995	0.000
Q75.4 Mandibulofacial dysostosis	0.005	0.995	0.000
Q75.3 Macrocephaly	0.005	0.995	0.000
Q75.2 Hypertelorism	0.005	0.995	0.000
Q75.1 Craniofacial dysostosis	0.005	0.995	0.000
Q75.0 Craniosynostosis	0.005	0.995	0.000
Q67.6 Pectus excavatum	0.005	0.995	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.005	0.995	0.000
Q79.5 Other congenital malformations of abdominal wall	0.005	0.995	0.000
Q79.4 Prune belly syndrome	0.005	0.995	0.000
Q79.3 Gastroschisis	0.005	0.995	0.000
Q79.2 Exomphalos	0.005	0.995	0.000
Q79.1 Other congenital malformations of diaphragm	0.005	0.995	0.000
Q79.0 Congenital diaphragmatic hernia	0.005	0.995	0.000
S01.3 Open wound of ear	0.005	0.995	0.000
I08.8 Other multiple valve diseases	0.005	0.995	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.005	0.995	0.000
Q68.4 Congenital bowing of tibia and fibula	0.005	0.995	0.000
Q68.3 Congenital bowing of femur	0.005	0.995	0.000
Q68.2 Congenital deformity of knee	0.005	0.995	0.000
Q68.1 Congenital deformity of hand	0.005	0.995	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.005	0.995	0.000
Q67.8 Other congenital deformities of chest	0.005	0.995	0.000
Q67.7 Pectus carinatum	0.005	0.995	0.000
Q67.3 Plagiocephaly	0.005	0.995	0.000
Q67.2 Dolichocephaly	0.005	0.995	0.000
Q67.1 Compression facies	0.005	0.995	0.000
Q67.0 Facial asymmetry	0.005	0.995	0.000
Q67.5 Congenital deformity of spine	0.005	0.995	0.000
M54.39 Sciatica (Site unspecified)	0.000	0.995	0.005
Q68.8 Other specified congenital musculoskeletal deformities	0.004	0.995	0.000
S06.5 Traumatic subdural haemorrhage	0.004	0.996	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.004	0.996	0.000
Q66.8 Other congenital deformities of feet	0.004	0.996	0.000
Q79.6 Ehlers-Danlos syndrome	0.004	0.996	0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.004	0.996	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.004	0.996	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.004	0.996	0.000
I08.9 Multiple valve disease, unspecified	0.004	0.996	0.000
D06 Carcinoma in situ of cervix uteri	0.004	0.996	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.004	0.996	0.000
D06.0 Endocervix	0.004	0.996	0.000
K86 Other diseases of pancreas	0.000	0.996	0.004
R23.2 Flushing	0.004	0.996	0.000
O03.4 Incomplete, without complication	0.004	0.996	0.000
Z92.8 Personal history of other medical treatment	0.000	0.996	0.004
Q39.6 Diverticulum of oesophagus	0.003	0.996	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.003	0.996	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.003	0.997	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.997	0.003
I08.2 Disorders of both aortic and tricuspid valves	0.003	0.997	0.000
K86.3 Pseudocyst of pancreas	0.000	0.997	0.003
H52.0 Hypermetropia	0.000	0.997	0.003
H57.8 Other specified disorders of eye and adnexa	0.003	0.997	0.000
O75.3 Other infection during labour	0.003	0.997	0.000
O75.8 Other specified complications of labour and delivery	0.003	0.997	0.000
K86.1 Other chronic pancreatitis	0.000	0.997	0.003
D06.7 Other parts of cervix	0.003	0.997	0.000
O75.9 Complication of labour and delivery, unspecified	0.003	0.997	0.000
O75.4 Other complications of obstetric surgery and procedures	0.003	0.997	0.000
O75.1 Shock during or following labour and delivery	0.003	0.997	0.000
T51 Toxic effect of alcohol	0.000	0.997	0.003
O75.0 Maternal distress during labour and delivery	0.003	0.997	0.000
H52.2 Astigmatism	0.000	0.997	0.003
K86.8 Other specified diseases of pancreas	0.000	0.997	0.003
D06.1 Exocervix	0.003	0.997	0.000
O63.9 Long labour, unspecified	0.000	0.997	0.003
E16 Other disorders of pancreatic internal secretion	0.000	0.997	0.003
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.003	0.997	0.000
K38.8 Other specified diseases of appendix	0.003	0.997	0.000
H31.1 Choroidal degeneration	0.003	0.997	0.000
L60 Nail disorders	0.003	0.997	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.000	0.997	0.002
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.997	0.003
G31.8 Other specified degenerative diseases of nervous system	0.002	0.997	0.000
H52.7 Disorder of refraction, unspecified	0.000	0.998	0.002
H35.4 Peripheral retinal degeneration	0.000	0.998	0.002
G44.2 Tension-type headache	0.000	0.998	0.002
T51.8 Other alcohols	0.000	0.998	0.002
T51.3 Fusel oil	0.000	0.998	0.002
T51.2 2-Propanol	0.000	0.998	0.002
T51.1 Methanol	0.000	0.998	0.002
S22.20 Fracture of sternum (closed)	0.000	0.998	0.002
Q39 Congenital malformations of oesophagus	0.002	0.998	0.000
L60.9 Nail disorder, unspecified	0.002	0.998	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.998	0.002
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.998	0.002
E16.4 Abnormal secretion of gastrin	0.000	0.998	0.002
E16.3 Increased secretion of glucagon	0.000	0.998	0.002
K62.8 Other specified diseases of anus and rectum	0.002	0.998	0.000
R23.1 Pallor	0.002	0.998	0.000
L60.3 Nail dystrophy	0.002	0.998	0.000
E16.1 Other hypoglycaemia	0.000	0.998	0.002
H52 Disorders of refraction and accommodation	0.000	0.998	0.002
H31.8 Other specified disorders of choroid	0.002	0.998	0.000
L60.1 Onycholysis	0.002	0.998	0.000
L60.5 Yellow nail syndrome	0.002	0.998	0.000
L60.4 Beau's lines	0.002	0.998	0.000
M16.7 Other secondary coxarthrosis	0.002	0.998	0.000
O03 Spontaneous abortion	0.002	0.998	0.000
G53.0 Postzoster neuralgia	0.000	0.998	0.002
N99.3 Prolapse of vaginal vault after hysterectomy	0.000	0.998	0.002
T51.9 Alcohol, unspecified	0.000	0.998	0.002
K42.9 Umbilical hernia without obstruction or gangrene	0.002	0.998	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.002	0.998	0.000
F22.0 Delusional disorder	0.002	0.998	0.000
K42.0 Umbilical hernia with obstruction, without gangrene	0.002	0.998	0.000
S06 Intracranial injury	0.002	0.998	0.000
G44.0 Cluster headache syndrome	0.000	0.998	0.002
O03.8 Complete or unspecified, with other and unspecified complications	0.002	0.998	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.002	0.998	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.998	0.002
Q39.8 Other congenital malformations of oesophagus	0.002	0.998	0.000
Q39.5 Congenital dilatation of oesophagus	0.002	0.998	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.002	0.998	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.002	0.998	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.002	0.998	0.000
Q39.0 Atresia of oesophagus without fistula	0.002	0.998	0.000
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.002	0.998	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.998	0.002
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.998	0.002
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.002	0.998	0.000
S06.1 Traumatic cerebral oedema	0.002	0.998	0.000
W10.8 Other specified place	0.000	0.998	0.002
H31 Other disorders of choroid	0.002	0.998	0.000
R23 Other skin changes	0.002	0.998	0.000
H35.5 Hereditary retinal dystrophy	0.000	0.998	0.002
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.002	0.998	0.000
E87.7 Fluid overload	0.000	0.998	0.002
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.998	0.002
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.002	0.998	0.000
S06.3 Focal brain injury	0.002	0.998	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
H31.3 Choroidal haemorrhage and rupture	0.002	0.998	0.000
H52.6 Other disorders of refraction	0.000	0.998	0.002
H52.5 Disorders of accommodation	0.000	0.998	0.002
R23.8 Other and unspecified skin changes	0.002	0.998	0.000
G44 Other headache syndromes	0.000	0.998	0.002
L60.2 Onychogryphosis	0.002	0.998	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.002	0.998	0.000
H52.4 Presbyopia	0.000	0.998	0.002
S06.2 Diffuse brain injury	0.002	0.998	0.000
Z61.6 Problems related to alleged physical abuse of child	0.002	0.998	0.000
C73 Malignant neoplasm of thyroid gland	0.000	0.998	0.002
S06.30 Focal brain injury (without open intracranial wound)	0.002	0.998	0.000
G31.0 Circumscribed brain atrophy	0.002	0.998	0.000
O03.7 Complete or unspecified, complicated by embolism	0.002	0.998	0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.002	0.998	0.000
O03.2 Incomplete, complicated by embolism	0.002	0.998	0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.002	0.998	0.000
S92.30 Fracture of metatarsal bone (closed)	0.002	0.998	0.000
G31.2 Degeneration of nervous system due to alcohol	0.002	0.998	0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.002	0.998	0.000
S06.7 Intracranial injury with prolonged coma	0.002	0.998	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.002	0.998	0.000
N92.6 Irregular menstruation, unspecified	0.000	0.998	0.002
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.002	0.998	0.000
I74 Arterial embolism and thrombosis	0.000	0.998	0.002
O24 Diabetes mellitus in pregnancy	0.002	0.998	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998	0.000
B94.8 Sequelae of other specified infectious and parasitic diseases	0.000	0.998	0.002
O24.9 Diabetes mellitus in pregnancy, unspecified	0.002	0.998	0.000
G44.4 Drug-induced headache, not elsewhere classified	0.000	0.998	0.002
K42 Umbilical hernia	0.002	0.998	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
Q44.5 Other congenital malformations of bile ducts	0.002	0.998	0.000
S06.9 Intracranial injury, unspecified	0.002	0.998	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.001	0.998	0.000
K42.1 Umbilical hernia with gangrene	0.002	0.998	0.000
Q17.5 Prominent ear	0.000	0.998	0.001
G44.3 Chronic posttraumatic headache	0.000	0.998	0.002
H31.9 Disorder of choroid, unspecified	0.001	0.998	0.000
H31.4 Choroidal detachment	0.001	0.998	0.000
H31.2 Hereditary choroidal dystrophy	0.001	0.998	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.998	0.002
S06.31 Focal brain injury (with open intracranial wound)	0.001	0.998	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.998	0.002
S06.0 Concussion	0.002	0.998	0.000
Z61 Problems related to negative life events in childhood	0.002	0.998	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.002	0.998	0.000
S06.4 Epidural haemorrhage	0.001	0.998	0.000
D73.0 Hyposplenism	0.002	0.998	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.001	0.998	0.000
M10.90 Gout, unspecified (Multiple sites)	0.000	0.998	0.002
S06.21 Diffuse brain injury (with open intracranial wound)	0.001	0.998	0.000
S72.10 Pertrochanteric fracture (closed)	0.002	0.998	0.000
I22.8 Subsequent myocardial infarction of other sites	0.002	0.998	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.998	0.001
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.002	0.998	0.000
Q44.6 Cystic disease of liver	0.001	0.998	0.000
Z51.3 Blood transfusion without reported diagnosis	0.002	0.998	0.000
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.001	0.998	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.001	0.998	0.000
G44.8 Other specified headache syndromes	0.000	0.998	0.001
G44.1 Vascular headache, not elsewhere classified	0.000	0.998	0.001
O03.3 Incomplete, with other and unspecified complications	0.001	0.998	0.000
Q39.4 Oesophageal web	0.001	0.998	0.000
R23.4 Changes in skin texture	0.001	0.998	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.002	0.998	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.001	0.998	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.001	0.998	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.001	0.998	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.001	0.998	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.001	0.998	0.000
Q44.7 Other congenital malformations of liver	0.001	0.998	0.000
Q44.4 Choledochal cyst	0.001	0.998	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.001	0.998	0.000
Q44.2 Atresia of bile ducts	0.001	0.998	0.000
Q44.1 Other congenital malformations of gallbladder	0.001	0.998	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.001	0.998	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.001	0.998	0.000
Q45 Other congenital malformations of digestive system	0.001	0.998	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.001	0.998	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.001	0.998	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.000	0.999	0.001
M10.92 Gout, unspecified (Upper arm)	0.000	0.999	0.001
M19.00 Primary arthrosis of other joints (Multiple sites)	0.000	0.999	0.001
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.001	0.999	0.000
J43.9 Emphysema, unspecified	0.001	0.999	0.000
Z34.8 Supervision of other normal pregnancy	0.001	0.999	0.000
M79.99 Soft tissue disorder, unspecified (Site unspecified)	0.001	0.999	0.000
Z80.6 Family history of leukaemia	0.000	0.999	0.001
Q40 Other congenital malformations of upper alimentary tract	0.001	0.999	0.000
M79.94 Soft tissue disorder, unspecified (Hand)	0.001	0.999	0.000
S06.01 Concussion (with open intracranial wound)	0.001	0.999	0.000
K86.9 Disease of pancreas, unspecified	0.000	0.999	0.001
L60.8 Other nail disorders	0.001	0.999	0.000
N99.1 Postprocedural urethral stricture	0.000	0.999	0.001
Q05.7 Lumbar spina bifida without hydrocephalus	0.001	0.999	0.000
Q30.9 Congenital malformation of nose, unspecified	0.001	0.999	0.000
Z61.9 Negative life events in childhood, unspecified	0.001	0.999	0.000
Z61.8 Other negative life events in childhood	0.001	0.999	0.000
Z61.7 Personal frightening experience in childhood	0.001	0.999	0.000
Z61.3 Events resulting in loss of self-esteem in childhood	0.001	0.999	0.000
Z61.2 Altered pattern of family relationships in childhood	0.001	0.999	0.000
Z61.1 Removal from home in childhood	0.001	0.999	0.000
Z61.0 Loss of love relationship in childhood	0.001	0.999	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.001	0.999	0.000
D38.1 Trachea, bronchus and lung	0.000	0.999	0.001
I05.2 Mitral stenosis with insufficiency	0.001	0.999	0.000
Q45.8 Other specified congenital malformations of digestive system	0.001	0.999	0.000
S06.8 Other intracranial injuries	0.001	0.999	0.000
Q30 Congenital malformations of nose	0.001	0.999	0.000
C71.2 Temporal lobe	0.000	0.999	0.001
F05.0 Delirium not superimposed on dementia, so described	0.001	0.999	0.000
F06.7 Mild cognitive disorder	0.001	0.999	0.000
H31.0 Chorioretinal scars	0.001	0.999	0.000
S12.7 Multiple fractures of cervical spine	0.000	0.999	0.001
Q30-Q34 Congenital malformations of the respiratory system	0.001	0.999	0.000
M65.14 Other infective (teno)synovitis (Hand)	0.001	0.999	0.000
D03.5 Melanoma in situ of trunk	0.000	0.999	0.001
Q17 Other congenital malformations of ear	0.000	0.999	0.001
M47.87 Other spondylosis (Lumbosacral region)	0.000	0.999	0.001
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.001	0.999	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.001	0.999	0.000
N49.2 Inflammatory disorders of scrotum	0.000	0.999	0.001
R23.0 Cyanosis	0.001	0.999	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.001	0.999	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.001	0.999	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.999	0.001
H57.1 Ocular pain	0.001	0.999	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.001	0.999	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.001	0.999	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.001	0.999	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.001	0.999	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.001	0.999	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.001	0.999	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.001	0.999	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.001	0.999	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.001	0.999	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.001	0.999	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.001	0.999	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.001	0.999	0.000
Q45.2 Congenital pancreatic cyst	0.001	0.999	0.000
Q45.1 Annular pancreas	0.001	0.999	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.001	0.999	0.000
Q99.8 Other specified chromosome abnormalities	0.001	0.999	0.000
F09 Unspecified organic or symptomatic mental disorder	0.001	0.999	0.000
H57 Other disorders of eye and adnexa	0.001	0.999	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.001	0.999	0.000
Q96 Turner's syndrome	0.001	0.999	0.000
O08.0 Genital tract and pelvic infection following abortion and ectopic and molar pregnancy	0.001	0.999	0.000
Q06.8 Other specified congenital malformations of spinal cord	0.001	0.999	0.000
Q43.1 Hirschsprung's disease	0.001	0.999	0.000
Q96.9 Turner's syndrome, unspecified	0.001	0.999	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.000	0.999	0.001
H10.9 Conjunctivitis, unspecified	0.001	0.999	0.000
Q30.3 Congenital perforated nasal septum	0.001	0.999	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.001	0.999	0.000
Q40.2 Other specified congenital malformations of stomach	0.001	0.999	0.000
Q40.1 Congenital hiatus hernia	0.001	0.999	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.001	0.999	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.001	0.999	0.000
Q06 Other congenital malformations of spinal cord	0.001	0.999	0.000
Q05 Spina bifida	0.001	0.999	0.000
Q18 Other congenital malformations of face and neck	0.000	0.999	0.001
Q00-Q07 Congenital malformations of the nervous system	0.001	0.999	0.000
M79.80 Other specified soft tissue disorders (Multiple sites)	0.001	0.999	0.000
F05.9 Delirium, unspecified	0.001	0.999	0.000
F20.0 Paranoid schizophrenia	0.001	0.999	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.001	0.999	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.999	0.001
R26.3 Immobility	0.000	0.999	0.001
S06.81 Other intracranial injuries (with open intracranial wound)	0.001	0.999	0.000
O42.9 Premature rupture of membranes, unspecified	0.001	0.999	0.000
Q30.8 Other congenital malformations of nose	0.001	0.999	0.000
Q30.2 Fissured, notched and cleft nose	0.001	0.999	0.000
Q30.1 Agenesis and underdevelopment of nose	0.001	0.999	0.000
Q30.0 Choanal atresia	0.001	0.999	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.001	0.999	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.001	0.999	0.000
Q34 Other congenital malformations of respiratory system	0.001	0.999	0.000
Q33 Congenital malformations of lung	0.001	0.999	0.000
Q32 Congenital malformations of trachea and bronchus	0.001	0.999	0.000
Q31 Congenital malformations of larynx	0.001	0.999	0.000
Q90 Down's syndrome	0.001	0.999	0.000
S12.71 Multiple fractures of cervical spine (open)	0.000	0.999	0.001
B02.2 Zoster with other nervous system involvement	0.000	0.999	0.001
C71.1 Frontal lobe	0.000	0.999	0.001
N21.1 Calculus in urethra	0.001	0.999	0.000
O03.9 Complete or unspecified, without complication	0.001	0.999	0.000
Q17.9 Congenital malformation of ear, unspecified	0.000	0.999	0.001
Q17.8 Other specified congenital malformations of ear	0.000	0.999	0.001
Q17.4 Misplaced ear	0.000	0.999	0.001
Q17.3 Other misshapen ear	0.000	0.999	0.001
Q17.2 Microtia	0.000	0.999	0.001
Q17.1 Macrotia	0.000	0.999	0.001
Q17.0 Accessory auricle	0.000	0.999	0.001
F03 Unspecified dementia	0.001	0.999	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.001	0.999	0.000
Q18.1 Preauricular sinus and cyst	0.000	0.999	0.001
Q31.3 Laryngocele	0.001	0.999	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.001	0.999	0.000
F22 Persistent delusional disorders	0.001	0.999	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.001	0.999	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.001	0.999	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.001	0.999	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.001	0.999	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.001	0.999	0.000
S06.00 Concussion (without open intracranial wound)	0.001	0.999	0.000
Q96.8 Other variants of Turner's syndrome	0.001	0.999	0.000
Q96.4 Mosaicism, 45,X/other cell line(s) with abnormal sex chromosome	0.001	0.999	0.000
Q96.3 Mosaicism, 45,X/46,XX or XY	0.001	0.999	0.000
Q96.2 Karyotype 46,X with abnormal sex chromosome, except iso (Xq)	0.001	0.999	0.000
Q96.1 Karyotype 46,X iso (Xq)	0.001	0.999	0.000
Q96.0 Karyotype 45,X	0.001	0.999	0.000
Q99.9 Chromosomal abnormality, unspecified	0.001	0.999	0.000
Q99.2 Fragile X chromosome	0.001	0.999	0.000
Q99.1 46,XX true hermaphrodite	0.001	0.999	0.000
Q99.0 Chimera 46,XX/46,XY	0.001	0.999	0.000
S22.2 Fracture of sternum	0.000	0.999	0.001
Q43 Other congenital malformations of intestine	0.001	0.999	0.000
M79.98 Soft tissue disorder, unspecified (Other)	0.001	0.999	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.001	0.999	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.001	0.999	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations