TreeWAS – Variant ID: rs4704296

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C71.9 Brain, unspecified	0.000	0.361	0.639
C71 Malignant neoplasm of brain	0.000	0.371	0.629
C71.1 Frontal lobe	0.000	0.381	0.619
C71.2 Temporal lobe	0.000	0.473	0.527
C71.0 Cerebrum, except lobes and ventricles	0.000	0.490	0.510
C71.7 Brain stem	0.000	0.505	0.495
C71.4 Occipital lobe	0.000	0.523	0.477
C71.6 Cerebellum	0.000	0.540	0.460
C71.5 Cerebral ventricle	0.000	0.549	0.451
C71.8 Overlapping lesion of brain	0.000	0.563	0.437
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.000	0.635	0.365
C71.3 Parietal lobe	0.000	0.664	0.336
C69 Malignant neoplasm of eye and adnexa	0.000	0.689	0.311
C70 Malignant neoplasm of meninges	0.000	0.716	0.284
C69.0 Conjunctiva	0.000	0.725	0.275
C69.3 Choroid	0.000	0.746	0.254
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.000	0.766	0.233
C70.0 Cerebral meninges	0.000	0.774	0.226
C69.9 Eye, unspecified	0.000	0.777	0.223
C69.8 Overlapping lesion of eye and adnexa	0.000	0.777	0.223
C69.5 Lachrymal gland and duct	0.000	0.777	0.223
C69.1 Cornea	0.000	0.777	0.223
C69.4 Ciliary body	0.000	0.782	0.218
C70.9 Meninges, unspecified	0.000	0.796	0.204
C70.1 Spinal meninges	0.000	0.796	0.204
C69.6 Orbit	0.000	0.797	0.203
C69.2 Retina	0.000	0.800	0.200
C72.9 Central nervous system, unspecified	0.000	0.832	0.167
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.000	0.832	0.167
C72.5 Other and unspecified cranial nerves	0.000	0.832	0.167
C72.4 Acoustic nerve	0.000	0.832	0.167
C72.3 Optic nerve	0.000	0.832	0.167
C72.2 Olfactory nerve	0.000	0.832	0.167
C72.1 Cauda equina	0.000	0.832	0.167
C72.0 Spinal cord	0.000	0.861	0.139
K51 Ulcerative colitis	0.000	0.872	0.128
K51.8 Other ulcerative colitis	0.000	0.873	0.127
K51.9 Ulcerative colitis, unspecified	0.000	0.875	0.125
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.877	0.123
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.888	0.112
K51.4 Pseudopolyposis of colon	0.000	0.893	0.107
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.914	0.086
K51.5 Mucosal proctocolitis	0.000	0.924	0.076
K51.2 Ulcerative (chronic) proctitis	0.000	0.941	0.059
K50-K52 Noninfective enteritis and colitis	0.000	0.963	0.037
K50.8 Other Crohn's disease	0.000	0.969	0.031
K50 Crohn's disease [regional enteritis]	0.000	0.970	0.030
S22.40 Multiple fractures of ribs (closed)	0.000	0.976	0.024
S22.4 Multiple fractures of ribs	0.000	0.977	0.023
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.978	0.022
K50.1 Crohn's disease of large intestine	0.000	0.978	0.022
S22.3 Fracture of rib	0.000	0.978	0.022
S22.30 Fracture of rib (closed)	0.000	0.979	0.021
S22.5 Flail chest	0.000	0.980	0.020
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.019	0.981	0.000
S22.50 Flail chest (closed)	0.000	0.982	0.018
S22.1 Multiple fractures of thoracic spine	0.000	0.982	0.018
S20-S29 Injuries to the thorax	0.000	0.982	0.018
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.983	0.017
S22.41 Multiple fractures of ribs (open)	0.000	0.983	0.017
S20 Superficial injury of thorax	0.000	0.984	0.016
S22.9 Fracture of bony thorax, part unspecified	0.000	0.984	0.016
S22.8 Fracture of other parts of bony thorax	0.000	0.984	0.016
S22.31 Fracture of rib (open)	0.000	0.984	0.016
S20.8 Superficial injuries of other and unspecified parts of thorax	0.000	0.984	0.015
S21 Open wound of thorax	0.000	0.985	0.015
S22.51 Flail chest (open)	0.000	0.986	0.014
S27 Injury of other and unspecified intrathoracic organs	0.000	0.986	0.014
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.986	0.014
S22.2 Fracture of sternum	0.000	0.986	0.014
S21.9 Open wound of thorax, part unspecified	0.000	0.986	0.014
S20.3 Other superficial injuries of front wall of thorax	0.000	0.987	0.013
S20.0 Contusion of breast	0.000	0.987	0.013
S24 Injury of nerves and spinal cord at thorax level	0.000	0.987	0.013
S22.11 Multiple fractures of thoracic spine (open)	0.000	0.987	0.013
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.000	0.987	0.013
S25 Injury of blood vessels of thorax	0.000	0.987	0.013
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.000	0.987	0.013
J98.9 Respiratory disorder, unspecified	0.013	0.987	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.013	0.987	0.000
J98 Other respiratory disorders	0.013	0.987	0.000
S26 Injury of heart	0.000	0.988	0.012
S21.1 Open wound of front wall of thorax	0.000	0.988	0.012
S27.3 Other injuries of lung	0.000	0.988	0.012
K60.3 Anal fistula	0.012	0.988	0.000
S20.4 Other superficial injuries of back wall of thorax	0.000	0.988	0.012
S22.81 Fracture of other parts of bony thorax (open)	0.000	0.988	0.012
S22.80 Fracture of other parts of bony thorax (closed)	0.000	0.988	0.012
S22.91 Fracture of bony thorax, part unspecified (open)	0.000	0.988	0.012
S22.90 Fracture of bony thorax, part unspecified (closed)	0.000	0.988	0.012
S27.1 Traumatic haemothorax	0.000	0.988	0.012
K50.0 Crohn's disease of small intestine	0.000	0.988	0.012
J98.4 Other disorders of lung	0.011	0.989	0.000
S21.8 Open wound of other parts of thorax	0.000	0.989	0.011
S21.7 Multiple open wounds of thoracic wall	0.000	0.989	0.011
S21.0 Open wound of breast	0.000	0.989	0.011
S20.7 Multiple superficial injuries of thorax	0.000	0.989	0.011
S20.2 Contusion of thorax	0.000	0.989	0.011
S20.1 Other and unspecified superficial injuries of breast	0.000	0.989	0.011
S27.2 Traumatic heamopneumothorax	0.000	0.989	0.011
K50.9 Crohn's disease, unspecified	0.000	0.989	0.011
J98.8 Other specified respiratory disorders	0.011	0.989	0.000
S22.0 Fracture of thoracic vertebra	0.000	0.989	0.011
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.000	0.989	0.011
J98.5 Diseases of mediastinum, not elsewhere classified	0.011	0.989	0.000
S27.9 Injury of unspecified intrathoracic organ	0.000	0.989	0.010
S27.7 Multiple injuries of intrathoracic organs	0.000	0.989	0.010
S27.6 Injury of pleura	0.000	0.989	0.010
S27.5 Injury of thoracic trachea	0.000	0.989	0.010
S27.4 Injury of bronchus	0.000	0.989	0.010
S21.2 Open wound of back wall of thorax	0.000	0.989	0.010
J98.2 Interstitial emphysema	0.010	0.989	0.000
S43.0 Dislocation of shoulder joint	0.011	0.989	0.000
S22.21 Fracture of sternum (open)	0.000	0.990	0.010
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.000	0.990	0.010
S24.1 Other and unspecified injuries of thoracic spinal cord	0.000	0.990	0.010
S27.8 Injury of other specified intrathoracic organs	0.000	0.990	0.010
S24.6 Injury of unspecified nerve of thorax	0.000	0.990	0.009
S24.5 Injury of other nerves of thorax	0.000	0.990	0.009
S24.4 Injury of thoracic sympathetic nerves	0.000	0.990	0.009
S24.3 Injury of peripheral nerves of thorax	0.000	0.990	0.009
S24.2 Injury of nerve root of thoracic spine	0.000	0.990	0.009
S24.0 Concussion and oedema of thoracic spinal cord	0.000	0.990	0.009
S29 Other and unspecified injuries of thorax	0.000	0.990	0.009
S25.9 Injury of unspecified blood vessel of thorax	0.000	0.990	0.009
S25.8 Injury of other blood vessels of thorax	0.000	0.990	0.009
S25.7 Injury of multiple blood vessels of thorax	0.000	0.990	0.009
S25.5 Injury of intercostal blood vessels	0.000	0.990	0.009
S25.4 Injury of pulmonary blood vessels	0.000	0.990	0.009
S25.3 Injury of innominate or subclavian vein	0.000	0.990	0.009
S25.2 Injury of superior vena cava	0.000	0.990	0.009
S25.1 Injury of innominate or subclavian artery	0.000	0.990	0.009
S25.0 Injury of thoracic aorta	0.000	0.990	0.009
S28.1 Traumatic amputation of part of thorax	0.000	0.990	0.009
S28.0 Crushed chest	0.000	0.990	0.009
S23.5 Sprain and strain of other and unspecified parts of thorax	0.000	0.991	0.009
S23.3 Sprain and strain of thoracic spine	0.000	0.991	0.009
S23.2 Dislocation of other and unspecified parts of thorax	0.000	0.991	0.009
S23.1 Dislocation of thoracic vertebra	0.000	0.991	0.009
S23.0 Traumatic rupture of thoracic intervertebral disk	0.000	0.991	0.009
S27.0 Traumatic pneumothorax	0.000	0.991	0.009
S23.4 Sprain and strain of ribs and sternum	0.000	0.991	0.009
J98.3 Compensatory emphysema	0.009	0.991	0.000
S26.9 Injury of heart, unspecified	0.000	0.991	0.009
S26.0 Injury of heart with haemopericardium	0.000	0.991	0.009
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.000	0.991	0.009
O69.2 Labour and delivery complicated by other cord entanglement	0.000	0.991	0.009
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.000	0.991	0.009
S26.8 Other injuries of heart	0.000	0.991	0.009
R59.9 Enlarged lymph nodes, unspecified	0.009	0.991	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.000	0.992	0.008
M70.6 Trochanteric bursitis	0.008	0.992	0.000
S22.20 Fracture of sternum (closed)	0.000	0.992	0.008
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.000	0.992	0.008
S22.01 Fracture of thoracic vertebra (open)	0.000	0.992	0.008
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.000	0.992	0.008
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.000	0.992	0.008
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.000	0.992	0.008
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.000	0.992	0.008
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.000	0.992	0.008
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.000	0.992	0.008
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.000	0.992	0.008
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.000	0.992	0.008
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.000	0.992	0.008
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.000	0.992	0.008
J98.6 Disorders of diaphragm	0.008	0.992	0.000
K55.0 Acute vascular disorders of intestine	0.008	0.992	0.000
K52 Other non-infective gastro-enteritis and colitis	0.000	0.993	0.007
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.000	0.993	0.007
S29.0 Injury of muscle and tendon at thorax level	0.000	0.993	0.007
S29.7 Multiple injuries of thorax	0.000	0.993	0.007
S26.01 Injury of heart with haemopericardium (with open wound into thoracic cavity)	0.000	0.993	0.007
S26.00 Injury of heart with haemopericardium (without open wound into thoracic cavity)	0.000	0.993	0.007
S26.91 Injury of heart, unspecified (with open wound into thoracic cavity)	0.000	0.993	0.007
S26.90 Injury of heart, unspecified (without open wound into thoracic cavity)	0.000	0.993	0.007
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.000	0.993	0.007
S26.81 Other injuries of heart (with open wound into thoracic cavity)	0.000	0.993	0.006
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.000	0.993	0.006
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.000	0.994	0.006
J99 Respiratory disorders in diseases classified elsewhere	0.006	0.994	0.000
O46.9 Antepartum haemorrhage, unspecified	0.000	0.994	0.006
M70.68 Trochanteric bursitis-Other	0.006	0.994	0.000
M70.67 Trochanteric bursitis-Ankle/Foot	0.006	0.994	0.000
M70.66 Trochanteric bursitis-Lower Leg	0.006	0.994	0.000
M70.64 Trochanteric bursitis-Hand	0.006	0.994	0.000
M70.63 Trochanteric bursitis-Forearm	0.006	0.994	0.000
M70.62 Trochanteric bursitis-Upper arm	0.006	0.994	0.000
M70.61 Trochanteric bursitis-Shldr region	0.006	0.994	0.000
M70.60 Trochanteric bursitis-Mult sites	0.006	0.994	0.000
J95-J99 Other diseases of the respiratory system	0.006	0.994	0.000
S26.80 Other injuries of heart (without open wound into thoracic cavity)	0.000	0.994	0.006
S29.9 Unspecified injury of thorax	0.000	0.994	0.006
J99.8 Respiratory disorders in other diseases classified elsewhere	0.006	0.994	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.994	0.006
J99.0 Rheumatoid lung disease	0.006	0.994	0.000
M70.69 Trochanteric bursitis-Site unspec	0.006	0.994	0.000
C15.5 Lower third of oesophagus	0.000	0.994	0.006
K52.8 Other specified non-infective gastro-enteritis and colitis	0.000	0.995	0.005
H80.9 Otosclerosis, unspecified	0.005	0.995	0.000
S29.8 Other specified injuries of thorax	0.001	0.995	0.005
O69 Labour and delivery complicated by umbilical cord complications	0.000	0.995	0.005
J96 Respiratory failure, not elsewhere classified	0.005	0.995	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.000	0.995	0.005
K55.1 Chronic vascular disorders of intestine	0.005	0.995	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.000	0.995	0.005
I78.0 Hereditary haemorrhagic telangiectasia	0.005	0.995	0.000
L43.9 Lichen planus, unspecified	0.005	0.995	0.000
K55 Vascular disorders of intestine	0.005	0.995	0.000
E27.1 Primary adrenocortical insufficiency	0.004	0.996	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.000	0.996	0.004
E27.4 Other and unspecified adrenocortical insufficiency	0.004	0.996	0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.004	0.996	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.000	0.996	0.004
I78.1 Naevus, nonneoplastic	0.004	0.996	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.004	0.996	0.000
C25.9 Pancreas, unspecified	0.004	0.996	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.000	0.996	0.004
O69.4 Labour and delivery complicated by vasa praevia	0.000	0.996	0.004
O69.3 Labour and delivery complicated by short cord	0.000	0.996	0.004
D21.2 Connective and other soft tissue of lower limb, including hip	0.004	0.996	0.000
E27 Other disorders of adrenal gland	0.004	0.996	0.000
O69.8 Labour and delivery complicated by other cord complications	0.000	0.996	0.004
Q23.1 Congenital insufficiency of aortic valve	0.004	0.996	0.000
D37.0 Lip, oral cavity and pharynx	0.004	0.996	0.000
J96.9 Respiratory failure, unspecified	0.003	0.996	0.000
J96.1 Chronic respiratory failure	0.003	0.996	0.000
J96.0 Acute respiratory failure	0.003	0.996	0.000
F32.1 Moderate depressive episode	0.004	0.996	0.000
T92.1 Sequelae of fracture of arm	0.000	0.996	0.004
K55.8 Other vascular disorders of intestine	0.004	0.996	0.000
K52.1 Toxic gastro-enteritis and colitis	0.000	0.996	0.003
C25 Malignant neoplasm of pancreas	0.004	0.996	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.000	0.996	0.004
I78 Diseases of capillaries	0.004	0.996	0.000
K55.2 Angiodysplasia of colon	0.003	0.997	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.000	0.997	0.003
O69.0 Labour and delivery complicated by prolapse of cord	0.000	0.997	0.003
C25.0 Head of pancreas	0.003	0.997	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.003	0.997	0.000
O66 Other obstructed labour	0.000	0.997	0.003
C25.2 Tail of pancreas	0.003	0.997	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.003	0.997	0.000
E20-E35 Disorders of other endocrine glands	0.003	0.997	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.003	0.997	0.000
C25.3 Pancreatic duct	0.003	0.997	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.003	0.997	0.000
S43.2 Dislocation of sternoclavicular joint	0.003	0.997	0.000
C25.7 Other parts of pancreas	0.003	0.997	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.003	0.997	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.000	0.997	0.003
S43.1 Dislocation of acromioclavicular joint	0.003	0.997	0.000
E20 Hypoparathyroidism	0.003	0.997	0.000
O66.2 Obstructed labour due to unusually large foetus	0.000	0.997	0.003
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.003	0.997	0.000
G90 Disorders of autonomic nervous system	0.000	0.997	0.003
E27.5 Adrenomedullary hyperfunction	0.003	0.997	0.000
E27.0 Other adrenocortical overactivity	0.003	0.997	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.003	0.997	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.003
G90.3 Multisystem degeneration	0.000	0.997	0.003
S43.4 Sprain and strain of shoulder joint	0.003	0.997	0.000
O66.4 Failed trial of labour, unspecified	0.000	0.997	0.003
J96.09 Acute respiratory failure; Type unspecified	0.003	0.997	0.000
J96.01 Acute respiratory failure; Type II [hypercapnic]	0.003	0.997	0.000
J96.00 Acute respiratory failure; Type I [hypoxic]	0.003	0.997	0.000
J96.19 Chronic respiratory failure; Type unspecified	0.003	0.997	0.000
J96.11 Chronic respiratory failure; Type II [hypercapnic]	0.003	0.997	0.000
J96.10 Chronic respiratory failure; Type I [hypoxic]	0.003	0.997	0.000
J96.99 Respiratory failure, unspecified; Type unspecified	0.003	0.997	0.000
J96.91 Respiratory failure unspecified; Type II [hypercapnic]	0.003	0.997	0.000
J96.90 Respiratory failure, unspecified; Type I [hypoxic]	0.003	0.997	0.000
E29 Testicular dysfunction	0.003	0.997	0.000
E28 Ovarian dysfunction	0.003	0.997	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.003	0.997	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.000	0.997	0.003
G90.2 Horner's syndrome	0.000	0.997	0.003
K52.3 Indeterminate colitis	0.001	0.997	0.002
C25.1 Body of pancreas	0.003	0.997	0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.003	0.997	0.000
Q23 Congenital malformations of aortic and mitral valves	0.003	0.997	0.000
G90.8 Other disorders of autonomic nervous system	0.000	0.997	0.003
D21 Other benign neoplasms of connective and other soft tissue	0.003	0.997	0.000
E26 Hyperaldosteronism	0.003	0.997	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.003	0.997	0.000
S72.40 Fracture of lower end of femur (closed)	0.003	0.997	0.000
E20.1 Pseudohypoparathyroidism	0.003	0.997	0.000
O66.9 Obstructed labour, unspecified	0.000	0.997	0.003
E27.9 Disorder of adrenal gland, unspecified	0.003	0.997	0.000
E28.2 Polycystic ovarian syndrome	0.003	0.997	0.000
E27.2 Addisonian crisis	0.003	0.997	0.000
Y83.6 Removal of other organ (partial) (total)	0.003	0.997	0.000
E22 Hyperfunction of pituitary gland	0.003	0.997	0.000
E20.8 Other hypoparathyroidism	0.003	0.997	0.000
E31 Polyglandular dysfunction	0.003	0.997	0.000
C44.0 Skin of lip	0.000	0.997	0.003
G90.0 Idiopathic peripheral autonomic neuropathy	0.000	0.997	0.003
O66.8 Other specified obstructed labour	0.000	0.997	0.003
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.003	0.997	0.000
I78.9 Disease of capillaries, unspecified	0.003	0.997	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.000	0.997	0.003
O66.1 Obstructed labour due to locked twins	0.000	0.997	0.003
E20.9 Hypoparathyroidism, unspecified	0.003	0.997	0.000
C25.4 Endocrine pancreas	0.003	0.997	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.003	0.997	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.003	0.997	0.000
E32 Diseases of thymus	0.003	0.997	0.000
E30 Disorders of puberty, not elsewhere classified	0.003	0.997	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.003	0.997	0.000
L43 Lichen planus	0.003	0.997	0.000
C25.8 Overlapping lesion of pancreas	0.002	0.997	0.000
D21.4 Connective and other soft tissue of abdomen	0.002	0.997	0.000
E29.1 Testicular hypofunction	0.003	0.997	0.000
D21.9 Connective and other soft tissue, unspecified	0.002	0.997	0.000
E20.0 Idiopathic hypoparathyroidism	0.002	0.997	0.000
E29.9 Testicular dysfunction, unspecified	0.002	0.997	0.000
C44.1 Skin of eyelid, including canthus	0.000	0.997	0.003
E34 Other endocrine disorders	0.002	0.997	0.000
G90.4 Autonomic dysreflexia	0.000	0.997	0.002
G90.1 Familial dysautonomia [Riley-Day]	0.000	0.997	0.002
R60.9 Oedema, unspecified	0.003	0.997	0.000
D21.6 Connective and other soft tissue of trunk, unspecified	0.002	0.997	0.000
I78.8 Other diseases of capillaries	0.002	0.997	0.000
E25 Adrenogenital disorders	0.002	0.997	0.000
L43.0 Hypertrophic lichen planus	0.002	0.998	0.000
D21.5 Connective and other soft tissue of pelvis	0.002	0.998	0.000
E34.0 Carcinoid syndrome	0.002	0.998	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.002	0.998	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.998	0.002
E26.0 Primary hyperaldosteronism	0.002	0.998	0.000
E23.2 Diabetes insipidus	0.002	0.998	0.000
E26.9 Hyperaldosteronism, unspecified	0.002	0.998	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.002	0.998	0.000
E28.9 Ovarian dysfunction, unspecified	0.002	0.998	0.000
E28.8 Other ovarian dysfunction	0.002	0.998	0.000
E28.1 Androgen excess	0.002	0.998	0.000
E28.0 Oestrogen excess	0.002	0.998	0.000
E29.8 Other testicular dysfunction	0.002	0.998	0.000
E29.0 Testicular hyperfunction	0.002	0.998	0.000
O46.8 Other antepartum haemorrhage	0.000	0.998	0.002
O46.0 Antepartum haemorrhage with coagulation defect	0.000	0.998	0.002
Q23.3 Congenital mitral insufficiency	0.002	0.998	0.000
Z71.1 Person with feared complaint in whom no diagnosis is made	0.000	0.998	0.002
E31.0 Autoimmune polyglandular failure	0.002	0.998	0.000
K55.9 Vascular disorder of intestine, unspecified	0.002	0.998	0.000
N76.2 Acute vulvitis	0.002	0.998	0.000
Q28 Other congenital malformations of circulatory system	0.002	0.998	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.002	0.998	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.002	0.998	0.000
Q23.4 Hypoplastic left heart syndrome	0.002	0.998	0.000
Q23.2 Congenital mitral stenosis	0.002	0.998	0.000
E26.8 Other hyperaldosteronism	0.002	0.998	0.000
E26.1 Secondary hyperaldosteronism	0.002	0.998	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.002	0.998	0.000
E23 Hypofunction and other disorders of pituitary gland	0.002	0.998	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.002	0.998	0.000
E27.8 Other specified disorders of adrenal gland	0.002	0.998	0.000
Q21.0 Ventricular septal defect	0.002	0.998	0.000
S83.2 Tear of meniscus, current	0.002	0.998	0.000
Z37.0 Single live birth	0.000	0.998	0.002
S92.30 Fracture of metatarsal bone (closed)	0.002	0.998	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.002	0.998	0.000
E22.8 Other hyperfunction of pituitary gland	0.002	0.998	0.000
E31.9 Polyglandular dysfunction, unspecified	0.002	0.998	0.000
E31.8 Other polyglandular dysfunction	0.002	0.998	0.000
E31.1 Polyglandular hyperfunction	0.002	0.998	0.000
Q21 Congenital malformations of cardiac septa	0.002	0.998	0.000
T17.9 Foreign body in respiratory tract, part unspecified	0.002	0.998	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.000	0.998	0.002
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
E28.3 Primary ovarian failure	0.002	0.998	0.000
E34.3 Short stature, not elsewhere classified	0.002	0.998	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.000	0.998	0.002
T79.3 Post-traumatic wound infection, not elsewhere classified	0.000	0.998	0.002
H80 Otosclerosis	0.002	0.998	0.000
E30.9 Disorder of puberty, unspecified	0.002	0.998	0.000
E30.8 Other disorders of puberty	0.002	0.998	0.000
E30.1 Precocious puberty	0.002	0.998	0.000
E30.0 Delayed puberty	0.002	0.998	0.000
E32.9 Disease of thymus, unspecified	0.002	0.998	0.000
E32.8 Other diseases of thymus	0.002	0.998	0.000
E32.1 Abscess of thymus	0.002	0.998	0.000
E32.0 Persistent hyperplasia of thymus	0.002	0.998	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.002	0.998	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.002	0.998	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.002	0.998	0.000
L43.3 Subacute (active) lichen planus	0.002	0.998	0.000
L43.2 Lichenoid drug reaction	0.002	0.998	0.000
L43.1 Bullous lichen planus	0.002	0.998	0.000
Q23.0 Congenital stenosis of aortic valve	0.002	0.998	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.002	0.998	0.000
L90.5 Scar conditions and fibrosis of skin	0.000	0.998	0.002
R50.9 Fever, unspecified	0.002	0.998	0.000
E21.4 Other specified disorders of parathyroid gland	0.002	0.998	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.000	0.998	0.002
Q28.2 Arteriovenous malformation of cerebral vessels	0.002	0.998	0.000
E34.5 Androgen resistance syndrome	0.002	0.998	0.000
E34.4 Constitutional tall stature	0.002	0.998	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.002	0.998	0.000
E34.1 Other hypersecretion of intestinal hormones	0.002	0.998	0.000
O60-O75 Complications of labour and delivery	0.000	0.998	0.002
E25.9 Adrenogenital disorder, unspecified	0.002	0.998	0.000
E25.8 Other adrenogenital disorders	0.002	0.998	0.000
F43.0 Acute stress reaction	0.000	0.998	0.002
M70.0 Chronic crepitant synovitis of hand and wrist	0.002	0.998	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.002	0.998	0.000
E24 Cushing's syndrome	0.002	0.998	0.000
Q26 Congenital malformations of great veins	0.002	0.998	0.000
Q24 Other congenital malformations of heart	0.002	0.998	0.000
J95.5 Postprocedural subglottic stenosis	0.002	0.998	0.000
J95.4 Mendelson's syndrome	0.002	0.998	0.000
J95.3 Chronic pulmonary insufficiency following surgery	0.002	0.998	0.000
J95.2 Acute pulmonary insufficiency following nonthoracic surgery	0.002	0.998	0.000
J95.1 Acute pulmonary insufficiency following thoracic surgery	0.002	0.998	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.998	0.002
L43.8 Other lichen planus	0.002	0.998	0.000
Q21.8 Other congenital malformations of cardiac septa	0.002	0.998	0.000
S86 Injury of muscle and tendon at lower leg level	0.000	0.998	0.002
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.002	0.998	0.000
M81.9 Osteoporosis, unspecified	0.000	0.998	0.002
O71.4 Obstetric high vaginal laceration alone	0.000	0.998	0.002
E21.3 Hyperparathyroidism, unspecified	0.002	0.998	0.000
D21.0 Connective and other soft tissue of head, face and neck	0.002	0.998	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.998	0.002
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.000	0.998	0.002
D21.3 Connective and other soft tissue of thorax	0.002	0.998	0.000
E21.2 Other hyperparathyroidism	0.002	0.998	0.000
E22.1 Hyperprolactinaemia	0.002	0.998	0.000
H50.0 Convergent concomitant strabismus	0.002	0.998	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.002	0.998	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.002	0.998	0.000
Q28.3 Other malformations of cerebral vessels	0.002	0.998	0.000
Q28.1 Other malformations of precerebral vessels	0.002	0.998	0.000
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure	0.002	0.998	0.000
M70.8 Other soft tissue disorders related to use, overuse and pressure	0.002	0.998	0.000
M70.1 Bursitis of hand	0.002	0.998	0.000
O70.0 First degree perineal laceration during delivery	0.000	0.998	0.002
Q24.0 Dextrocardia	0.002	0.998	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.000	0.998	0.002
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.002	0.998	0.000
E23.1 Drug-induced hypopituitarism	0.002	0.998	0.000
E23.6 Other disorders of pituitary gland	0.002	0.998	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.002	0.998	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.002	0.998	0.000
N60.4 Mammary duct ectasia	0.000	0.998	0.002
Q21.4 Aortopulmonary septal defect	0.002	0.998	0.000
Q21.2 Atrioventricular septal defect	0.002	0.998	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.000	0.998	0.002
O71 Other obstetric trauma	0.000	0.998	0.002
Q20 Congenital malformations of cardiac chambers and connexions	0.002	0.998	0.000
M70.7 Other bursitis of hip	0.002	0.998	0.000
Q24.4 Congenital subaortic stenosis	0.002	0.998	0.000
R52.1 Chronic intractable pain	0.002	0.998	0.000
M70.04 Chronic crepitant synovitis of hand and wrist (Hand)	0.002	0.998	0.000
H80.8 Other otosclerosis	0.002	0.998	0.000
H80.2 Cochlear otosclerosis	0.002	0.998	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.002	0.998	0.000
D04.6 Skin of upper limb, including shoulder	0.000	0.998	0.002
M70.3 Other bursitis of elbow	0.002	0.998	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.998	0.002
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.998	0.002
J95.9 Postprocedural respiratory disorder, unspecified	0.001	0.998	0.001
M70.5 Other bursitis of knee	0.002	0.998	0.000
O70.9 Perineal laceration during delivery, unspecified	0.000	0.998	0.002
Q21.3 Tetralogy of Fallot	0.002	0.998	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.002	0.998	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.000	0.998	0.002
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
S82.60 Fracture of lateral malleolus (closed)	0.002	0.998	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.998	0.002
T90.9 Sequelae of unspecified injury of head	0.002	0.998	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.002	0.998	0.000
E24.8 Other Cushing's syndrome	0.002	0.998	0.000
Q24.6 Congenital heart block	0.002	0.998	0.000
Q61.2 Polycystic kidney, adult type	0.002	0.998	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.000	0.998	0.002
O60 Preterm delivery	0.000	0.998	0.002
M70.4 Prepatellar bursitis	0.002	0.998	0.000
Q24.3 Pulmonary infundibular stenosis	0.002	0.998	0.000
Q24.2 Cor triatriatum	0.002	0.998	0.000
Q24.1 Levocardia	0.002	0.998	0.000
Q61.3 Polycystic kidney, unspecified	0.002	0.998	0.000
S83.1 Dislocation of knee	0.002	0.998	0.000
S83.0 Dislocation of patella	0.002	0.998	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
M70.09 Chronic crepitant synovitis of hand and wrist-Site unspec	0.002	0.998	0.000
M70.08 Chronic crepitant synovitis of hand and wrist-Other	0.002	0.998	0.000
M70.07 Chronic crepitant synovitis of hand and wrist-Ankle/Foot	0.002	0.998	0.000
M70.06 Chronic crepitant synovitis of hand and wrist-Lower Leg	0.002	0.998	0.000
M70.05 Chronic crepitant synovitis of hand and wrist-Pelvic/Thigh	0.002	0.998	0.000
M70.03 Chronic crepitant synovitis of hand and wrist (Forearm)	0.002	0.998	0.000
M70.02 Chronic crepitant synovitis of hand and wrist-Upper arm	0.002	0.998	0.000
M70.01 Chronic crepitant synovitis of hand and wrist-Shldr region	0.002	0.998	0.000
M70.00 Chronic crepitant synovitis of hand and wrist (Multiple sites)	0.002	0.998	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.000	0.998	0.002
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.002	0.998	0.000
E24.3 Ectopic ACTH syndrome	0.002	0.998	0.000
E24.1 Nelson's syndrome	0.002	0.998	0.000
J95.0 Tracheostomy malfunction	0.001	0.998	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.000	0.998	0.002
Q26.9 Congenital malformation of great vein, unspecified	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations