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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4710154
log Bayes Factor = 23.8787
Chromosome 6   position 167,394,634  (GRCh37) Explore rs4710154 on Ensembl!
Variant rs4710154 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.002 0.998
C44.3 Skin of other and unspecified parts of face
0.997 0.003 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.004 0.996
E10-E14 Diabetes mellitus
0.000 0.004 0.996
E10 Insulin-dependent diabetes mellitus
0.000 0.007 0.993
E05.9 Thyrotoxicosis, unspecified
0.000 0.013 0.987
E50-E64 Other nutritional deficiencies
0.000 0.015 0.985
E53 Deficiency of other B group vitamins
0.000 0.020 0.980
E14 Unspecified diabetes mellitus
0.000 0.023 0.977
E53.8 Deficiency of other specified B group vitamins
0.000 0.024 0.976
E10.9 Without complications
0.000 0.031 0.969
C44 Other malignant neoplasms of skin
0.968 0.032 0.000
E10.4 With neurological complications
0.000 0.039 0.961
E07 Other disorders of thyroid
0.000 0.040 0.960
C44.5 Skin of trunk
0.959 0.041 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.062 0.938
E14.9 Without complications
0.000 0.066 0.934
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.081 0.919
C43-C44 Melanoma and other malignant neoplasms of skin
0.915 0.085 0.000
C43 Malignant melanoma of skin
0.905 0.095 0.000
C43.5 Malignant melanoma of trunk
0.896 0.104 0.000
E10.2 With renal complications
0.000 0.127 0.873
E14.4 With neurological complications
0.000 0.131 0.869
E03.8 Other specified hypothyroidism
0.000 0.148 0.852
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.153 0.847
E10.1 With ketoacidosis
0.000 0.174 0.826
C44.6 Skin of upper limb, including shoulder
0.805 0.195 0.000
E10.0 With coma
0.000 0.197 0.803
C43.9 Malignant melanoma of skin, unspecified
0.801 0.199 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.799 0.201 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.213 0.787
E53.9 Vitamin B deficiency, unspecified
0.000 0.231 0.769
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.236 0.764
E14.3 With ophthalmic complications
0.000 0.237 0.763
E51 Thiamine deficiency
0.000 0.249 0.750
C43.1 Malignant melanoma of eyelid, including canthus
0.747 0.253 0.000
C44.0 Skin of lip
0.737 0.262 0.000
E14.5 With peripheral circulatory complications
0.000 0.263 0.737
E14.2 Withrenal complications
0.000 0.271 0.729
E10.6 With other specified complications
0.000 0.275 0.725
E61 Deficiency of other nutrient elements
0.000 0.279 0.721
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.286 0.714
E10.7 With multiple complications
0.000 0.288 0.712
C44.9 Malignant neoplasm of skin, unspecified
0.712 0.288 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.294 0.706
E63 Other nutritional deficiencies
0.000 0.294 0.706
E50 Vitamin A deficiency
0.000 0.294 0.706
E60 Dietary zinc deficiency
0.000 0.294 0.706
E59 Dietary selenium deficiency
0.000 0.294 0.706
E58 Dietary calcium deficiency
0.000 0.294 0.706
E54 Ascorbic acid deficiency
0.000 0.294 0.706
E52 Niacin deficiency [pellagra]
0.000 0.294 0.706
E53.1 Pyridoxine deficiency
0.000 0.297 0.703
E53.0 Riboflavin deficiency
0.000 0.297 0.703
E14.7 With multiple complications
0.000 0.299 0.700
E14.0 With coma
0.000 0.299 0.700
E14.8 With unspecified complications
0.000 0.301 0.699
C44.8 Overlapping lesion of skin
0.694 0.306 0.000
E07.1 Dyshormogenetic goitre
0.000 0.311 0.688
E07.0 Hypersecretion of calcitonin
0.000 0.311 0.688
E14.1 With ketoacidosis
0.000 0.319 0.681
E56 Other vitamin deficiencies
0.000 0.329 0.671
C43.8 Overlapping malignant melanoma of skin
0.649 0.351 0.000
C43.0 Malignant melanoma of lip
0.649 0.351 0.000
E14.6 With other specified complications
0.000 0.355 0.645
E05.8 Other thyrotoxicosis
0.000 0.362 0.638
E16 Other disorders of pancreatic internal secretion
0.000 0.364 0.636
E10.8 With unspecified complications
0.000 0.364 0.636
E07.8 Other specified disorders of thyroid
0.000 0.380 0.620
C43.4 Malignant melanoma of scalp and neck
0.611 0.389 0.000
E40-E46 Malnutrition
0.000 0.399 0.601
C43.6 Malignant melanoma of upper limb, including shoulder
0.588 0.412 0.000
E51.2 Wernicke's encephalopathy
0.000 0.417 0.582
C44.2 Skin of ear and external auricular canal
0.578 0.422 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.436 0.564
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.436 0.563
E13 Other specified diabetes mellitus
0.000 0.437 0.563
E10.3 With ophthalmic complications
0.000 0.441 0.559
E61.2 Magnesium deficiency
0.000 0.452 0.548
E16.2 Hypoglycaemia, unspecified
0.000 0.453 0.547
E65-E68 Obesity and other hyperalimentation
0.000 0.455 0.545
E06 Thyroiditis
0.000 0.460 0.540
E51.9 Thiamine deficiency, unspecified
0.000 0.462 0.538
E51.8 Other manifestations of thiamine deficiency
0.000 0.462 0.538
E51.1 Beriberi
0.000 0.462 0.538
E61.9 Deficiency of nutrient element, unspecified
0.000 0.483 0.517
E61.8 Deficiency of other specified nutrient elements
0.000 0.483 0.517
E61.7 Deficiency of multiple nutrient elements
0.000 0.483 0.517
E61.6 Vanadium deficiency
0.000 0.483 0.517
E61.5 Molybdenum deficiency
0.000 0.483 0.517
E61.4 Chromium deficiency
0.000 0.483 0.517
E61.3 Manganese deficiency
0.000 0.483 0.517
E61.0 Copper deficiency
0.000 0.483 0.517
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.488 0.512
E12.8 With unspecified complications
0.000 0.488 0.512
E12.7 With multiple complications
0.000 0.488 0.512
E12.6 With other specified complications
0.000 0.488 0.512
E12.5 With peripheral circulatory complications
0.000 0.488 0.512
E12.4 With neurological complications
0.000 0.488 0.512
E12.3 With ophthalmic complications
0.000 0.488 0.512
E12.2 With renal complications
0.000 0.488 0.512
E12.1 With ketoacidosis
0.000 0.488 0.512
E12.0 With coma
0.000 0.488 0.512
E50.9 Vitamin A deficiency, unspecified
0.000 0.494 0.506
E50.8 Other manifestations of vitamin A deficiency
0.000 0.494 0.506
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.494 0.506
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.494 0.506
E50.5 Vitamin A deficiency with night blindness
0.000 0.494 0.506
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.494 0.506
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.494 0.506
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.494 0.506
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.494 0.506
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.494 0.506
E63.9 Nutritional deficiency, unspecified
0.000 0.494 0.506
E63.8 Other specified nutritional deficiencies
0.000 0.494 0.506
E63.1 Imbalance of constituents of food intake
0.000 0.494 0.506
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.494 0.506
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.494 0.506
E64.8 Sequelae of other nutritional deficiencies
0.000 0.494 0.506
E64.3 Sequelae of rickets
0.000 0.494 0.506
E64.2 Sequelae of vitamin C deficiency
0.000 0.494 0.506
E64.1 Sequelae of vitamin A deficiency
0.000 0.494 0.506
E64.0 Sequelae of protein-energy malnutrition
0.000 0.494 0.506
E61.1 Iron deficiency
0.000 0.503 0.497
E10.5 With peripheral circulatory complications
0.000 0.507 0.493
E56.9 Vitamin deficiency, unspecified
0.000 0.518 0.481
E56.8 Deficiency of other vitamins
0.000 0.518 0.481
E56.0 Deficiency of vitamin E
0.000 0.518 0.481
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.521 0.479
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.544 0.456
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.544 0.456
E16.4 Abnormal secretion of gastrin
0.000 0.544 0.456
E16.3 Increased secretion of glucagon
0.000 0.544 0.456
E55 Vitamin D deficiency
0.000 0.551 0.449
E56.1 Deficiency of vitamin K
0.000 0.553 0.446
C43.2 Malignant melanoma of ear and external auricular canal
0.435 0.565 0.001
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.569 0.431
E45 Retarded development following protein-energy malnutrition
0.000 0.569 0.431
E43 Unspecified severe protein-energy malnutrition
0.000 0.569 0.431
E42 Marasmic kwashiorkor
0.000 0.569 0.431
E41 Nutritional marasmus
0.000 0.569 0.431
E40 Kwashiorkor
0.000 0.569 0.431
E13.8 With unspecified complications
0.000 0.596 0.404
E13.7 With multiple complications
0.000 0.596 0.404
E13.6 With other specified complications
0.000 0.596 0.404
E13.5 With peripheral circulatory complications
0.000 0.596 0.404
E13.4 With neurological complications
0.000 0.596 0.404
E13.2 With renal complications
0.000 0.596 0.404
E13.1 With ketoacidosis
0.000 0.596 0.404
E13.0 With coma
0.000 0.596 0.404
E67 Other hyperalimentation
0.000 0.609 0.391
E68 Sequelae of hyperalimentation
0.000 0.609 0.391
E16.1 Other hypoglycaemia
0.000 0.611 0.389
E06.5 Other chronic thyroiditis
0.000 0.612 0.387
E06.4 Drug-induced thyroiditis
0.000 0.612 0.387
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.612 0.387
E06.0 Acute thyroiditis
0.000 0.612 0.387
E66 Obesity
0.000 0.614 0.386
E06.3 Autoimmune thyroiditis
0.000 0.615 0.385
E13.3 With ophthalmic complications
0.000 0.621 0.379
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.649 0.351
E06.1 Subacute thyroiditis
0.000 0.656 0.344
E55.0 Rickets, active
0.000 0.678 0.322
C44.1 Skin of eyelid, including canthus
0.320 0.680 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.682 0.317
E44.1 Mild protein-energy malnutrition
0.000 0.691 0.309
E44.0 Moderate protein-energy malnutrition
0.000 0.691 0.309
E66.8 Other obesity
0.000 0.691 0.309
C44.7 Skin of lower limb, including hip
0.298 0.702 0.000
E13.9 Without complications
0.000 0.706 0.294
E06.9 Thyroiditis, unspecified
0.000 0.712 0.288
E67.8 Other specified hyperalimentation
0.000 0.719 0.280
E67.3 Hypervitaminosis D
0.000 0.719 0.280
E67.2 Megavitamin-B6 syndrome
0.000 0.719 0.280
E67.1 Hypercarotenaemia
0.000 0.719 0.280
E67.0 Hypervitaminosis A
0.000 0.719 0.280
E66.1 Drug-induced obesity
0.000 0.723 0.277
E04 Other non-toxic goitre
0.000 0.730 0.270
L43.9 Lichen planus, unspecified
0.000 0.758 0.242
E66.0 Obesity due to excess calories
0.000 0.758 0.241
E20-E35 Disorders of other endocrine glands
0.000 0.760 0.240
E65 Localised adiposity
0.000 0.768 0.232
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.780 0.220
E04.0 Non-toxic diffuse goitre
0.000 0.791 0.209
E21.3 Hyperparathyroidism, unspecified
0.000 0.798 0.202
E04.8 Other specified non-toxic goitre
0.000 0.806 0.193
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.812 0.188
E25 Adrenogenital disorders
0.000 0.821 0.179
E26 Hyperaldosteronism
0.000 0.823 0.177
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.828 0.172
E32 Diseases of thymus
0.000 0.828 0.172
E31 Polyglandular dysfunction
0.000 0.828 0.172
E30 Disorders of puberty, not elsewhere classified
0.000 0.828 0.172
E28 Ovarian dysfunction
0.000 0.831 0.169
C43.7 Malignant melanoma of lower limb, including hip
0.163 0.837 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.842 0.158
E21.2 Other hyperparathyroidism
0.000 0.844 0.155
E20 Hypoparathyroidism
0.000 0.846 0.154
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.850 0.150
E24 Cushing's syndrome
0.000 0.851 0.149
E28.3 Primary ovarian failure
0.000 0.853 0.147
E21.0 Primary hyperparathyroidism
0.000 0.855 0.145
E29 Testicular dysfunction
0.000 0.861 0.139
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.864 0.136
E22 Hyperfunction of pituitary gland
0.000 0.866 0.134
L43 Lichen planus
0.000 0.867 0.133
E26.0 Primary hyperaldosteronism
0.000 0.867 0.133
E25.9 Adrenogenital disorder, unspecified
0.000 0.871 0.128
E25.8 Other adrenogenital disorders
0.000 0.871 0.128
E26.9 Hyperaldosteronism, unspecified
0.000 0.873 0.127
E26.8 Other hyperaldosteronism
0.000 0.873 0.127
E26.1 Secondary hyperaldosteronism
0.000 0.873 0.127
E23 Hypofunction and other disorders of pituitary gland
0.000 0.874 0.126
C44.4 Skin of scalp and neck
0.125 0.875 0.000
E30.9 Disorder of puberty, unspecified
0.000 0.876 0.123
E30.8 Other disorders of puberty
0.000 0.876 0.123
E30.1 Precocious puberty
0.000 0.876 0.123
E30.0 Delayed puberty
0.000 0.876 0.123
E31.9 Polyglandular dysfunction, unspecified
0.000 0.876 0.123
E31.8 Other polyglandular dysfunction
0.000 0.876 0.123
E31.1 Polyglandular hyperfunction
0.000 0.876 0.123
E31.0 Autoimmune polyglandular failure
0.000 0.876 0.123
E32.9 Disease of thymus, unspecified
0.000 0.876 0.123
E32.8 Other diseases of thymus
0.000 0.876 0.123
E32.1 Abscess of thymus
0.000 0.876 0.123
E32.0 Persistent hyperplasia of thymus
0.000 0.876 0.123
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.876 0.123
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.876 0.123
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.876 0.123
E28.9 Ovarian dysfunction, unspecified
0.000 0.879 0.121
E28.8 Other ovarian dysfunction
0.000 0.879 0.121
E28.1 Androgen excess
0.000 0.879 0.121
E28.0 Oestrogen excess
0.000 0.879 0.121
E04.1 Non-toxic single thyroid nodule
0.000 0.880 0.120
E04.2 Non-toxic multinodular goitre
0.000 0.883 0.117
E22.0 Acromegaly and pituitary gigantism
0.000 0.888 0.112
E20.8 Other hypoparathyroidism
0.000 0.889 0.111
E20.1 Pseudohypoparathyroidism
0.000 0.889 0.111
E20.0 Idiopathic hypoparathyroidism
0.000 0.889 0.111
L43.8 Other lichen planus
0.000 0.891 0.109
E24.8 Other Cushing's syndrome
0.000 0.893 0.107
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.893 0.107
E24.3 Ectopic ACTH syndrome
0.000 0.893 0.107
E24.1 Nelson's syndrome
0.000 0.893 0.107
E24.9 Cushing's syndrome, unspecified
0.000 0.895 0.105
E04.9 Non-toxic goitre, unspecified
0.000 0.898 0.102
E29.9 Testicular dysfunction, unspecified
0.000 0.900 0.100
E29.8 Other testicular dysfunction
0.000 0.900 0.100
E29.0 Testicular hyperfunction
0.000 0.900 0.100
E24.0 Pituitary-dependent Cushing's disease
0.000 0.901 0.099
E34 Other endocrine disorders
0.000 0.901 0.099
E23.0 Hypopituitarism
0.000 0.903 0.097
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.904 0.096
E22.8 Other hyperfunction of pituitary gland
0.000 0.904 0.096
E24.2 Drug-induced Cushing's syndrome
0.000 0.904 0.096
L43.3 Subacute (active) lichen planus
0.000 0.904 0.096
L43.2 Lichenoid drug reaction
0.000 0.904 0.096
L43.1 Bullous lichen planus
0.000 0.904 0.096
L43.0 Hypertrophic lichen planus
0.000 0.904 0.096
E20.9 Hypoparathyroidism, unspecified
0.000 0.907 0.093
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.910 0.090
E23.1 Drug-induced hypopituitarism
0.000 0.910 0.090
E23.2 Diabetes insipidus
0.000 0.916 0.084
E27 Other disorders of adrenal gland
0.000 0.917 0.083
G12.2 Motor neuron disease
0.000 0.918 0.082
E23.7 Disorder of pituitary gland, unspecified
0.000 0.922 0.078
E70-E90 Metabolic disorders
0.000 0.928 0.072
G12 Spinal muscular atrophy and related syndromes
0.000 0.928 0.072
E34.5 Androgen resistance syndrome
0.000 0.929 0.071
E34.4 Constitutional tall stature
0.000 0.929 0.071
E34.3 Short stature, not elsewhere classified
0.000 0.929 0.071
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.929 0.071
E34.1 Other hypersecretion of intestinal hormones
0.000 0.929 0.071
E22.1 Hyperprolactinaemia
0.000 0.931 0.069
E29.1 Testicular hypofunction
0.000 0.932 0.067
E83 Disorders of mineral metabolism
0.000 0.933 0.067
Z95.0 Presence of cardiac pacemaker
0.000 0.934 0.066
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.935 0.065
G11 Hereditary ataxia
0.000 0.935 0.065
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.935 0.065
E55.9 Vitamin D deficiency, unspecified
0.001 0.935 0.064
E83.3 Disorders of phosphorus metabolism
0.000 0.935 0.065
G11.9 Hereditary ataxia, unspecified
0.000 0.936 0.064
E23.6 Other disorders of pituitary gland
0.000 0.938 0.061
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.940 0.060
E27.5 Adrenomedullary hyperfunction
0.000 0.940 0.059
E27.0 Other adrenocortical overactivity
0.000 0.940 0.059
E79 Disorders of purine and pyrimidine metabolism
0.000 0.942 0.058
E34.9 Endocrine disorder, unspecified
0.000 0.942 0.058
E34.8 Other specified endocrine disorders
0.000 0.942 0.057
E27.9 Disorder of adrenal gland, unspecified
0.000 0.942 0.058
E28.2 Polycystic ovarian syndrome
0.000 0.942 0.057
E83.5 Disorders of calcium metabolism
0.000 0.944 0.056
G11.4 Hereditary spastic paraplegia
0.000 0.944 0.056
E83.1 Disorders of iron metabolism
0.000 0.944 0.056
E27.1 Primary adrenocortical insufficiency
0.000 0.946 0.054
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.946 0.054
E34.0 Carcinoid syndrome
0.001 0.948 0.052
E84 Cystic fibrosis
0.000 0.948 0.052
E77 Disorders of glycoprotein metabolism
0.000 0.948 0.052
E76 Disorders of glycosaminoglycan metabolism
0.000 0.948 0.052
E72 Other disorders of amino-acid metabolism
0.000 0.948 0.052
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.948 0.052
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.948 0.052
G12.9 Spinal muscular atrophy, unspecified
0.000 0.948 0.052
G12.8 Other spinal muscular atrophies and related syndromes
0.000 0.948 0.052
G12.1 Other inherited spinal muscular atrophy
0.000 0.948 0.052
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]
0.000 0.948 0.052
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.948 0.052
G10 Huntington's disease
0.000 0.950 0.050
E74 Other disorders of carbohydrate metabolism
0.000 0.951 0.049
E88 Other metabolic disorders
0.000 0.951 0.049
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.951 0.049
E83.8 Other disorders of mineral metabolism
0.000 0.951 0.049
E83.2 Disorders of zinc metabolism
0.000 0.951 0.049
E83.0 Disorders of copper metabolism
0.000 0.951 0.049
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.952 0.048
G14 Postpolio syndrome
0.000 0.952 0.048
E70 Disorders of aromatic amino-acid metabolism
0.000 0.952 0.048
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.000 0.953 0.047
G11.8 Other hereditary ataxias
0.000 0.953 0.047
G11.3 Cerebellar ataxia with defective DNA repair
0.000 0.953 0.047
G11.2 Late-onset cerebellar ataxia
0.000 0.953 0.047
G11.1 Early-onset cerebellar ataxia
0.000 0.953 0.047
G11.0 Congenital nonprogressive ataxia
0.000 0.953 0.047
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.956 0.044
E78.2 Mixed hyperlipidaemia
0.000 0.956 0.044
E73 Lactose intolerance
0.000 0.956 0.043
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.957 0.043
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.958 0.042
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.958 0.042
E79.1 Lesch-Nyhan syndrome
0.000 0.958 0.042
E27.2 Addisonian crisis
0.000 0.959 0.041
E75.5 Other lipid storage disorders
0.000 0.959 0.041
E88.2 Lipomatosis, not elsewhere classified
0.000 0.959 0.040
E85 Amyloidosis
0.000 0.960 0.040
E75.6 Lipid storage disorder, unspecified
0.000 0.961 0.039
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.961 0.039
E75.3 Sphingolipidosis, unspecified
0.000 0.961 0.039
E75.1 Other gangliosidosis
0.000 0.961 0.039
E75.0 GM2 gangliosidosis
0.000 0.961 0.039
E75.2 Other sphingolipidosis
0.000 0.962 0.038
E78.4 Other hyperlipidaemia
0.000 0.962 0.038
E71.3 Disorders of fatty-acid metabolism
0.000 0.962 0.037
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.962 0.037
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.962 0.037
E71.0 Maple-syrup-urine disease
0.000 0.962 0.037
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.962 0.037
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.962 0.037
E72.5 Disorders of glycine metabolism
0.000 0.962 0.037
E72.4 Disorders of ornithine metabolism
0.000 0.962 0.037
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.962 0.037
E72.2 Disorders of urea cycle metabolism
0.000 0.962 0.037
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.962 0.037
E72.0 Disorders of amino-acid transport
0.000 0.962 0.037
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.962 0.037
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.962 0.037
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.962 0.037
E76.2 Other mucopolysaccharidoses
0.000 0.962 0.037
E76.1 Mucopolysaccharidosis, type II
0.000 0.962 0.037
E76.0 Mucopolysaccharidosis, type I
0.000 0.962 0.037
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.962 0.037
E77.8 Other disorders of glycoprotein metabolism
0.000 0.962 0.037
E77.1 Defects in glycoprotein degradation
0.000 0.962 0.037
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.962 0.037
E84.9 Cystic fibrosis, unspecified
0.000 0.962 0.037
E84.8 Cystic fibrosis with other manifestations
0.000 0.962 0.037
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.962 0.037
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.962 0.037
E89.2 Postprocedural hypoparathyroidism
0.000 0.963 0.037
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.963 0.037
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.965 0.035
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.965 0.035
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.965 0.035
E74.2 Disorders of galactose metabolism
0.000 0.965 0.035
E74.1 Disorders of fructose metabolism
0.000 0.965 0.035
E74.0 Glycogen storage disease
0.000 0.965 0.035
E78.8 Other disorders of lipoprotein metabolism
0.000 0.965 0.035
E88.8 Other specified metabolic disorders
0.000 0.965 0.035
E27.8 Other specified disorders of adrenal gland
0.000 0.965 0.035
E88.9 Metabolic disorder, unspecified
0.000 0.965 0.035
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.965 0.034
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.965 0.034
E70.2 Disorders of tyrosine metabolism
0.000 0.965 0.034
E70.1 Other hyperphenylalaninaemias
0.000 0.965 0.034
E70.0 Classical phenylketonuria
0.000 0.965 0.034
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere
0.000 0.966 0.034
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema
0.000 0.966 0.034
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease
0.000 0.966 0.034
G13.0 Paraneoplastic neuromyopathy and neuropathy
0.000 0.966 0.034
E78.1 Pure hyperglyceridaemia
0.000 0.968 0.032
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.968 0.032
E78.3 Hyperchylomicronaemia
0.000 0.968 0.032
E73.8 Other lactose intolerance
0.000 0.969 0.031
E73.1 Secondary lactase deficiency
0.000 0.969 0.031
E73.0 Congenital lactase deficiency
0.000 0.969 0.031
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.969 0.031
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.969 0.031
E89.5 Postprocedural testicular hypofunction
0.000 0.969 0.031
E89.1 Postprocedural hypoinsulinaemia
0.000 0.969 0.031
E88.3 Tumour lysis syndrome
0.000 0.969 0.031
E70.3 Albinism
0.000 0.970 0.030
E78.6 Lipoprotein deficiency
0.000 0.970 0.030
E85.8 Other amyloidosis
0.000 0.971 0.029
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.971 0.029
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.971 0.029
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.971 0.029
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.972 0.028
E89.0 Postprocedural hypothyroidism
0.000 0.972 0.028
E85.4 Organ-limited amyloidosis
0.000 0.973 0.027
E85.9 Amyloidosis, unspecified
0.000 0.974 0.026
E89.3 Postprocedural hypopituitarism
0.000 0.975 0.025
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.975 0.025
E89.4 Postprocedural ovarian failure
0.000 0.976 0.023
E85.3 Secondary systemic amyloidosis
0.000 0.976 0.023
E73.9 Lactose intolerance, unspecified
0.000 0.977 0.023
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.979 0.021
K50.9 Crohn's disease, unspecified
0.000 0.984 0.016
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.985 0.015
E80.5 Crigler-Najjar syndrome
0.000 0.985 0.015
E80.3 Defects of catalase and peroxydase
0.000 0.985 0.015
E80.0 Hereditary erythropoietic porphyria
0.000 0.985 0.015
Z45.0 Adjustment and management of cardiac pacemaker
0.000 0.986 0.014
E80.2 Other porphyria
0.000 0.986 0.013
L40-L45 Papulosquamous disorders
0.000 0.986 0.014
E80.1 Porphyria cutanea tarda
0.000 0.986 0.013
E80.6 Other disorders of bilirubin metabolism
0.000 0.988 0.012
K50 Crohn's disease [regional enteritis]
0.000 0.988 0.012
K50.8 Other Crohn's disease
0.000 0.989 0.011
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.989 0.011
E83.4 Disorders of magnesium metabolism
0.000 0.989 0.011
L41 Parapsoriasis
0.000 0.990 0.010
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.990 0.010
E86 Volume depletion
0.000 0.990 0.010
K50.0 Crohn's disease of small intestine
0.000 0.990 0.010
E11 Non-insulin-dependent diabetes mellitus
0.000 0.990 0.010
L44 Other papulosquamous disorders
0.000 0.991 0.009
E11.0 With coma
0.000 0.991 0.009
L03.0 Cellulitis of finger and toe
0.000 0.992 0.008
D23.3 Skin of other and unspecified parts of face
0.000 0.992 0.008
E78.5 Hyperlipidaemia, unspecified
0.000 0.992 0.008
L42 Pityriasis rosea
0.000 0.992 0.007
L41.9 Parapsoriasis, unspecified
0.000 0.992 0.007
L41.8 Other parapsoriasis
0.000 0.992 0.007
L41.5 Retiform parapsoriasis
0.000 0.992 0.007
L41.4 Large plaque parapsoriasis
0.000 0.992 0.007
L41.3 Small plaque parapsoriasis
0.000 0.992 0.007
L41.2 Lymphomatoid papulosis
0.000 0.992 0.007
L41.1 Pityriasis lichenoides chronica
0.000 0.992 0.007
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.992 0.007
E11.7 With multiple complications
0.000 0.993 0.007
E80.4 Gilbert's syndrome
0.000 0.993 0.007
K52.1 Toxic gastro-enteritis and colitis
0.000 0.993 0.007
L44.9 Papulosquamous disorder, unspecified
0.000 0.993 0.007
L44.8 Other specified papulosquamous disorders
0.000 0.993 0.007
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.993 0.007
L44.3 Lichen ruber moniliformis
0.000 0.993 0.007
L44.2 Lichen striatus
0.000 0.993 0.007
L44.1 Lichen nitidus
0.000 0.993 0.007
E11.8 With unspecified complications
0.000 0.993 0.007
R16.1 Splenomegaly, not elsewhere classified
0.000 0.994 0.006
Y60.0 During surgical operation
0.006 0.994 0.000
E11.2 With renal complications
0.000 0.994 0.006
L44.0 Pityriasis rubra pilaris
0.000 0.994 0.005
E66.9 Obesity, unspecified
0.000 0.994 0.006
M79.67 Pain in limb (Ankle and foot)
0.000 0.995 0.005
C32.1 Supraglottis
0.005 0.995 0.000
E11.6 With other specified complications
0.000 0.995 0.005
K50-K52 Noninfective enteritis and colitis
0.000 0.995 0.005
K50.1 Crohn's disease of large intestine
0.000 0.995 0.005
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified
0.000 0.995 0.005
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.005 0.995 0.000
K92.0 Haematemesis
0.000 0.995 0.005
C32.0 Glottis
0.005 0.995 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.000 0.995 0.005
K52 Other non-infective gastro-enteritis and colitis
0.000 0.995 0.005
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.000 0.995 0.005
K52.0 Gastro-enteritis and colitis due to radiation
0.000 0.995 0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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