TreeWAS – Variant ID: rs4778138

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C44 Other malignant neoplasms of skin	0.000	0.252	0.748
C44.3 Skin of other and unspecified parts of face	0.000	0.253	0.747
C44.6 Skin of upper limb, including shoulder	0.000	0.254	0.746
C44.4 Skin of scalp and neck	0.000	0.322	0.678
C44.0 Skin of lip	0.000	0.357	0.643
C44.7 Skin of lower limb, including hip	0.000	0.381	0.619
C44.2 Skin of ear and external auricular canal	0.000	0.451	0.549
C44.8 Overlapping lesion of skin	0.000	0.463	0.536
C44.1 Skin of eyelid, including canthus	0.000	0.473	0.527
C43-C44 Melanoma and other malignant neoplasms of skin	0.000	0.483	0.517
C43 Malignant melanoma of skin	0.000	0.529	0.471
C43.5 Malignant melanoma of trunk	0.000	0.571	0.429
C44.9 Malignant neoplasm of skin, unspecified	0.000	0.582	0.417
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.609	0.391
C43.9 Malignant melanoma of skin, unspecified	0.000	0.619	0.381
C43.6 Malignant melanoma of upper limb, including shoulder	0.000	0.653	0.347
C43.8 Overlapping malignant melanoma of skin	0.000	0.662	0.337
C43.1 Malignant melanoma of eyelid, including canthus	0.000	0.662	0.337
C43.0 Malignant melanoma of lip	0.000	0.662	0.337
C43.2 Malignant melanoma of ear and external auricular canal	0.000	0.683	0.317
C43.4 Malignant melanoma of scalp and neck	0.000	0.709	0.291
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.710	0.289
C44.5 Skin of trunk	0.000	0.818	0.182
K90.0 Coeliac disease	0.000	0.911	0.089
H40.1 Primary open-angle glaucoma	0.084	0.916	0.000
D70 Agranulocytosis	0.080	0.920	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.079	0.921	0.000
H40 Glaucoma	0.077	0.923	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.075	0.925	0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.074	0.926	0.000
H40.0 Glaucoma suspect	0.073	0.927	0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.072	0.928	0.000
H40.2 Primary angle-closure glaucoma	0.065	0.935	0.000
H40.9 Glaucoma, unspecified	0.059	0.941	0.000
H40.8 Other glaucoma	0.058	0.942	0.000
H40.6 Glaucoma secondary to drugs	0.055	0.945	0.000
H40.4 Glaucoma secondary to eye inflammation	0.055	0.945	0.000
H40.3 Glaucoma secondary to eye trauma	0.055	0.945	0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.055	0.945	0.000
H40.5 Glaucoma secondary to other eye disorders	0.050	0.950	0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.048	0.952	0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.037	0.963	0.000
H40-H42 Glaucoma	0.032	0.968	0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.000	0.973	0.027
K90 Intestinal malabsorption	0.001	0.975	0.024
H42 Glaucoma in diseases classified elsewhere	0.023	0.977	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.021	0.979	0.000
K90.3 Pancreatic steatorrhoea	0.001	0.982	0.018
K90.2 Blind loop syndrome, not elsewhere classified	0.001	0.982	0.018
K90.1 Tropical sprue	0.001	0.982	0.018
H42.8 Glaucoma in other diseases classified elsewhere	0.017	0.983	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.017	0.983	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.983	0.016
K90.8 Other intestinal malabsorption	0.001	0.984	0.016
D74 Methaemoglobinaemia	0.015	0.985	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.015	0.985	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.015	0.985	0.000
D73 Diseases of spleen	0.015	0.985	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.001	0.986	0.013
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.014	0.986	0.000
Y43.3 Other antineoplastic drugs	0.014	0.986	0.000
D75 Other diseases of blood and blood-forming organs	0.013	0.987	0.000
D73.1 Hypersplenism	0.013	0.987	0.000
D73.4 Cyst of spleen	0.012	0.988	0.000
D72 Other disorders of white blood cells	0.011	0.988	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.011	0.989	0.000
D74.9 Methaemoglobinaemia, unspecified	0.011	0.989	0.000
D74.8 Other methaemoglobinaemias	0.011	0.989	0.000
D74.0 Congenital methaemoglobinaemia	0.011	0.989	0.000
D73.9 Disease of spleen, unspecified	0.011	0.989	0.000
D73.3 Abscess of spleen	0.011	0.989	0.000
D73.2 Chronic congestive splenomegaly	0.011	0.989	0.000
D75.1 Secondary polycythaemia	0.010	0.990	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.010	0.990	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.010	0.990	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.010	0.990	0.000
N80.9 Endometriosis, unspecified	0.000	0.990	0.010
D73.8 Other diseases of spleen	0.010	0.990	0.000
D75.0 Familial erythrocytosis	0.010	0.990	0.000
D73.5 Infarction of spleen	0.008	0.991	0.000
D76.3 Other histiocytosis syndromes	0.008	0.991	0.000
D72.9 Disorder of white blood cells, unspecified	0.008	0.991	0.000
D72.0 Genetic anomalies of leukocytes	0.008	0.991	0.000
C50.4 Upper-outer quadrant of breast	0.009	0.991	0.000
D72.1 Eosinophilia	0.008	0.992	0.000
K92.2 Gastro-intestinal haemorrhage, unspecified	0.000	0.992	0.008
D75.2 Essential thrombocytosis	0.008	0.992	0.000
Y43 Primarily systemic agents	0.007	0.993	0.000
D73.0 Hyposplenism	0.007	0.993	0.000
N80 Endometriosis	0.000	0.993	0.007
D80-D89 Certain disorders involving the immune mechanism	0.007	0.993	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.007	0.993	0.000
D83 Common variable immunodeficiency	0.006	0.994	0.000
D80 Immunodeficiency with predominantly antibody defects	0.006	0.994	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.006	0.994	0.000
D83.9 Common variable immunodeficiency, unspecified	0.006	0.994	0.000
N80.8 Other endometriosis	0.000	0.994	0.006
N80.1 Endometriosis of ovary	0.000	0.994	0.006
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.006	0.994	0.000
N80.2 Endometriosis of Fallopian tube	0.000	0.994	0.006
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.006	0.994	0.000
Y43.1 Antineoplastic antimetabolites	0.006	0.994	0.000
C67.9 Bladder, unspecified	0.006	0.994	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.006	0.994	0.000
Y43.9 Primarily systemic agent, unspecified	0.005	0.994	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.005	0.994	0.000
Y43.6 Enzymes, not elsewhere classified	0.005	0.994	0.000
Y43.5 Acidifying and alkalising agents	0.005	0.994	0.000
Y43.2 Antineoplastic natural products	0.005	0.994	0.000
D84 Other immunodeficiencies	0.005	0.995	0.000
K90-K93 Other diseases of the digestive system	0.001	0.995	0.004
D51 Vitamin B12 deficiency anaemia	0.005	0.995	0.000
D72.8 Other specified disorders of white blood cells	0.005	0.995	0.000
N80.6 Endometriosis in cutaneous scar	0.000	0.995	0.005
N80.4 Endometriosis of rectovaginal septum and vagina	0.000	0.995	0.005
Y43.4 Immunosuppressive agents	0.005	0.995	0.000
D82 Immunodeficiency associated with other major defects	0.005	0.995	0.000
D81 Combined immunodeficiencies	0.005	0.995	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.005	0.995	0.000
C54.1 Endometrium	0.005	0.995	0.000
D83.8 Other common variable immunodeficiencies	0.005	0.995	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.005	0.995	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.005	0.995	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.005	0.995	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.005	0.995	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.005	0.995	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.005	0.995	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.005	0.995	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.005	0.995	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.005	0.995	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.005	0.995	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.005	0.995	0.000
J30.1 Allergic rhinitis due to pollen	0.000	0.995	0.005
Y42.7 Androgens and anabolic congeners	0.005	0.995	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.005	0.995	0.000
D50-D53 Nutritional anaemias	0.005	0.995	0.000
N80.5 Endometriosis of intestine	0.000	0.995	0.005
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.005	0.995	0.000
N80.0 Endometriosis of uterus	0.000	0.995	0.005
Y43.0 Antiallergic and antiemetic drugs	0.004	0.995	0.000
D84.9 Immunodeficiency, unspecified	0.004	0.995	0.000
K92 Other diseases of digestive system	0.002	0.995	0.003
D55-D59 Haemolytic anaemias	0.004	0.996	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.004	0.996	0.000
D89.3 Immune reconstitution syndrome	0.004	0.996	0.000
D89.1 Cryoglobulinaemia	0.004	0.996	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.004	0.996	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.004	0.996	0.000
C54 Malignant neoplasm of corpus uteri	0.004	0.996	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.004	0.996	0.000
D84.8 Other specified immunodeficiencies	0.004	0.996	0.000
D84.1 Defects in the complement system	0.004	0.996	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.004	0.996	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.996	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.004	0.996	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.004	0.996	0.000
D51.2 Transcobalamin II deficiency	0.004	0.996	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.004	0.996	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.001	0.996	0.003
C67 Malignant neoplasm of bladder	0.004	0.996	0.000
C67.3 Anterior wall of bladder	0.004	0.996	0.000
Y60.0 During surgical operation	0.004	0.996	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.004	0.996	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.004	0.996	0.000
Y54.8 Agents affecting uric acid metabolism	0.004	0.996	0.000
D81.9 Combined immunodeficiency, unspecified	0.004	0.996	0.000
D81.8 Other combined immunodeficiencies	0.004	0.996	0.000
D81.7 Major histocompatibility complex class II deficiency	0.004	0.996	0.000
D81.6 Major histocompatibility complex class I deficiency	0.004	0.996	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.004	0.996	0.000
D81.4 Nezelof's syndrome	0.004	0.996	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.004	0.996	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.004	0.996	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.004	0.996	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.004	0.996	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.004	0.996	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.004	0.996	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.004	0.996	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.004	0.996	0.000
D82.2 Immunodeficiency with short-limbed stature	0.004	0.996	0.000
D82.1 Di George's syndrome	0.004	0.996	0.000
D82.0 Wiskott-Aldrich syndrome	0.004	0.996	0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.004	0.996	0.000
N42.9 Disorder of prostate, unspecified	0.004	0.996	0.000
Y42.5 Other oestrogens and progestogens	0.004	0.996	0.000
X63.0 Home	0.004	0.996	0.000
M95.0 Acquired deformity of nose	0.004	0.996	0.000
D22.4 Melanocytic naevi of scalp and neck	0.000	0.996	0.004
Y60.5 During heart catheterisation	0.004	0.996	0.000
D86 Sarcoidosis	0.004	0.996	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.004	0.996	0.000
C54.9 Corpus uteri, unspecified	0.004	0.996	0.000
Y58 Bacterial vaccines	0.004	0.996	0.000
C67.1 Dome of bladder	0.004	0.996	0.000
N80.3 Endometriosis of pelvic peritoneum	0.000	0.996	0.004
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.004	0.996	0.000
Chapter XX External causes of morbidity and mortality	0.004	0.996	0.000
C51-C58 Malignant neoplasms of female genital organs	0.004	0.996	0.000
X60-X84 Intentional self-harm	0.004	0.996	0.000
C67.4 Posterior wall of bladder	0.003	0.996	0.000
Y52 Agents primarily affecting the cardiovascular system	0.003	0.996	0.000
Y44 Agents primarily affecting blood constituents	0.003	0.996	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.996	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.003	0.996	0.000
D57 Sickle-cell disorders	0.003	0.997	0.000
D56 Thalassaemia	0.003	0.997	0.000
D55 Anaemia due to enzyme disorders	0.003	0.997	0.000
D58 Other hereditary haemolytic anaemias	0.003	0.997	0.000
K92.1 Melaena	0.003	0.997	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.003	0.997	0.000
C56 Malignant neoplasm of ovary	0.003	0.997	0.000
C54.8 Overlapping lesion of corpus uteri	0.003	0.997	0.000
C54.3 Fundus uteri	0.003	0.997	0.000
C54.2 Myometrium	0.003	0.997	0.000
C54.0 Isthmus uteri	0.003	0.997	0.000
D53 Other nutritional anaemias	0.003	0.997	0.000
Y60.8 During other surgical and medical care	0.003	0.997	0.000
Y59 Other and unspecified vaccines and biological substances	0.003	0.997	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.997	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.003	0.997	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.003	0.997	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.003	0.997	0.000
Y60.4 During endoscopic examination	0.003	0.997	0.000
C67.8 Overlapping lesion of bladder	0.003	0.997	0.000
Y48 Anaesthetics and therapeutic gases	0.003	0.997	0.000
W20-W49 Exposure to inanimate mechanical forces	0.003	0.997	0.000
Y42.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
Y42.4 Oral contraceptives	0.003	0.997	0.000
Y42.2 Antithyroid drugs	0.003	0.997	0.000
Y42.1 Thyroid hormones and substitutes	0.003	0.997	0.000
W50-W64 Exposure to animate mechanical forces	0.003	0.997	0.000
K92.8 Other specified diseases of digestive system	0.001	0.997	0.002
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.001	0.997	0.002
K93.1 Megacolon in Chagas' disease	0.001	0.997	0.002
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.001	0.997	0.002
C67.7 Urachus	0.003	0.997	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
H47.3 Other disorders of optic disk	0.000	0.997	0.003
Y41 Other systemic anti-infectives and antiparasitics	0.003	0.997	0.000
Y79 Orthopaedic devices associated with adverse incidents	0.003	0.997	0.000
Y54.3 Benzothiadiazine derivatives	0.003	0.997	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.003	0.997	0.000
K91.4 Colostomy and enterostomy malfunction	0.003	0.997	0.000
Y60.9 During unspecified surgical and medical care	0.003	0.997	0.000
Y60.7 During administration of enema	0.003	0.997	0.000
Y60.6 During aspiration, puncture and other catheterisation	0.003	0.997	0.000
Y60.3 During injection or immunisation	0.003	0.997	0.000
Y60.2 During kidney dialysis or other perfusion	0.003	0.997	0.000
Y60.1 During infusion or transfusion	0.003	0.997	0.000
C53 Malignant neoplasm of cervix uteri	0.003	0.997	0.000
Y54.9 Mineral salts, not elsewhere classified	0.003	0.997	0.000
Y54.7 Agents affecting calcification	0.003	0.997	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.003	0.997	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.003	0.997	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.003	0.997	0.000
Y54.0 Mineralocorticoids	0.003	0.997	0.000
V20-V29 Motorcycle rider injured in transport accident	0.003	0.997	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.003	0.997	0.000
Y54.5 Other diuretics	0.003	0.997	0.000
Y58.0 BCG vaccine	0.003	0.997	0.000
Z93.2 Ileostomy status	0.003	0.997	0.000
Y54.4 Loop [high-ceiling] diuretics	0.003	0.997	0.000
C57 Malignant neoplasm of other and unspecified female genital organs	0.003	0.997	0.000
W49 Exposure to other and unspecified inanimate mechanical forces	0.003	0.997	0.000
Y52.1 Calcium-channel blockers	0.003	0.997	0.000
C67.0 Trigone of bladder	0.003	0.997	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.003	0.997	0.000
W20 Struck by thrown, projected or falling object	0.003	0.997	0.000
D86.3 Sarcoidosis of skin	0.003	0.997	0.000
Y73 Gastro-enterology and urology devices associated with adverse incidents	0.003	0.997	0.000
Y79.2 Prosthetic and other implants, materials and accessory devices	0.003	0.997	0.000
V40-V49 Car occupant injured in transport accident	0.003	0.997	0.000
Y10-Y34 Event of undetermined intent	0.003	0.997	0.000
C67.2 Lateral wall of bladder	0.003	0.997	0.000
V49.9 Car occupant [any] injured in unspecified traffic accident	0.003	0.997	0.000
Z90.7 Acquired absence of genital organ(s)	0.003	0.997	0.000
W20.8 Other specified place	0.003	0.997	0.000
X59 Exposure to unspecified factor	0.003	0.997	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.003	0.997	0.000
C53.0 Endocervix	0.003	0.997	0.000
W22 Striking against or struck by other objects	0.003	0.997	0.000
C67.6 Ureteric orifice	0.003	0.997	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.003	0.997	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.003	0.997	0.000
D52 Folate deficiency anaemia	0.003	0.997	0.000
D59 Acquired haemolytic anaemia	0.003	0.997	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.000	0.997	0.003
X78 Intentional self-harm by sharp object	0.003	0.997	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.003	0.997	0.000
W22.2 School, other institution and public administrative area	0.003	0.997	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.003	0.997	0.000
Y77 Ophthalmic devices associated with adverse incidents	0.003	0.997	0.000
V20 Motorcycle rider injured in collision with pedestrian or animal	0.003	0.997	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.003	0.997	0.000
C57.0 Fallopian tube	0.003	0.997	0.000
D86.1 Sarcoidosis of lymph nodes	0.003	0.997	0.000
H47.1 Papilloedema, unspecified	0.000	0.997	0.003
W49.0 Home	0.003	0.997	0.000
X10-X19 Contact with heat and hot substances	0.003	0.997	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.000	0.997	0.003
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.003	0.997	0.000
V49 Car occupant injured in other and unspecified transport accidents	0.003	0.997	0.000
Y64 Contaminated medical or biological substances	0.003	0.997	0.000
Y63 Failure in dosage during surgical and medical care	0.003	0.997	0.000
Y62 Failure of sterile precautions during surgical and medical care	0.003	0.997	0.000
Y61 Foreign object accidentally left in body during surgical and medical care	0.003	0.997	0.000
Y69 Unspecified misadventure during surgical and medical care	0.003	0.997	0.000
Y66 Nonadministration of surgical and medical care	0.003	0.997	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.003	0.997	0.000
X59.3 Sports and athletics area	0.003	0.997	0.000
Y58.9 Other and unspecified bacterial vaccines	0.003	0.997	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.003	0.997	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.003	0.997	0.000
Y58.5 Diphtheria vaccine	0.003	0.997	0.000
Y58.4 Tetanus vaccine	0.003	0.997	0.000
Y58.3 Plague vaccine	0.003	0.997	0.000
Y58.2 Cholera vaccine	0.003	0.997	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.003	0.997	0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.003	0.997	0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances	0.003	0.997	0.000
X63.9 Unspecified place	0.003	0.997	0.000
X63.8 Other specified place	0.003	0.997	0.000
X63.7 Farm	0.003	0.997	0.000
X63.6 Industrial and construction area	0.003	0.997	0.000
X63.5 Trade and service area	0.003	0.997	0.000
X63.4 Street and highway	0.003	0.997	0.000
X63.3 Sports and athletics area	0.003	0.997	0.000
X63.2 School, other institution and public administrative area	0.003	0.997	0.000
X63.1 Residential institution	0.003	0.997	0.000
Y73.2 Prosthetic and other implants, materials and accessory devices	0.003	0.997	0.000
Y46.2 Hydantoin derivatives	0.003	0.997	0.000
Y48.2 Other and unspecified general anaesthetics	0.003	0.997	0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.003	0.997	0.000
Y35-Y36 Legal intervention and operations of war	0.003	0.997	0.000
Y00-Y09 Assault	0.003	0.997	0.000
X85-X99 Assault	0.003	0.997	0.000
X30-X39 Exposure to forces of nature	0.003	0.997	0.000
X00-X09 Exposure to smoke, fire and flames	0.003	0.997	0.000
W75-W84 Other accidental threats to breathing	0.003	0.997	0.000
W65-W74 Accidental drowning and submersion	0.003	0.997	0.000
V98-V99 Other and unspecified transport accidents	0.003	0.997	0.000
V95-V97 Air and space transport accidents	0.003	0.997	0.000
V90-V94 Water transport accidents	0.003	0.997	0.000
V70-V79 Bus occupant injured in transport accident	0.003	0.997	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.003	0.997	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.003	0.997	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.003	0.997	0.000
W49.9 Unspecified place	0.003	0.997	0.000
C58 Malignant neoplasm of placenta	0.003	0.997	0.000
C52 Malignant neoplasm of vagina	0.003	0.997	0.000
X84 Intentional self-harm by unspecified means	0.003	0.997	0.000
X83 Intentional self-harm by other specified means	0.003	0.997	0.000
X82 Intentional self-harm by crashing of motor vehicle	0.003	0.997	0.000
X81 Intentional self-harm by jumping or lying before moving object	0.003	0.997	0.000
X80 Intentional self-harm by jumping from a high place	0.003	0.997	0.000
X79 Intentional self-harm by blunt object	0.003	0.997	0.000
X77 Intentional self-harm by steam, hot vapours and hot objects	0.003	0.997	0.000
X76 Intentional self-harm by smoke, fire and flames	0.003	0.997	0.000
X75 Intentional self-harm by explosive material	0.003	0.997	0.000
X74 Intentional self-harm by other and unspecified firearm discharge	0.003	0.997	0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge	0.003	0.997	0.000
X72 Intentional self-harm by handgun discharge	0.003	0.997	0.000
X71 Intentional self-harm by drowning and submersion	0.003	0.997	0.000
X70 Intentional self-harm by hanging, strangulation and suffocation	0.003	0.997	0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours	0.003	0.997	0.000
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours	0.003	0.997	0.000
X65 Intentional self-poisoning by and exposure to alcohol	0.003	0.997	0.000
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.003	0.997	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.003	0.997	0.000
Y44.7 Plasma substitutes	0.003	0.997	0.000
Y44.6 Natural blood and blood products	0.003	0.997	0.000
Y44.5 Thrombolytic drugs	0.003	0.997	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.003	0.997	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.003	0.997	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.003	0.997	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.997	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.003	0.997	0.000
Y52.7 Peripheral vasodilators	0.003	0.997	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.003	0.997	0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics	0.003	0.997	0.000
V01-V09 Pedestrian injured in transport accident	0.003	0.997	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.002	0.997	0.000
D55.8 Other anaemias due to enzyme disorders	0.002	0.997	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.002	0.997	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.002	0.997	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.002	0.997	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.002	0.997	0.000
D56.9 Thalassaemia, unspecified	0.002	0.997	0.000
D56.8 Other thalassaemias	0.002	0.997	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.002	0.997	0.000
D56.3 Thalassaemia trait	0.002	0.997	0.000
D56.2 Delta-beta thalassaemia	0.002	0.997	0.000
D56.1 Beta thalassaemia	0.002	0.997	0.000
D56.0 Alpha thalassaemia	0.002	0.997	0.000
D57.8 Other sickle-cell disorders	0.002	0.997	0.000
D57.3 Sickle-cell trait	0.002	0.997	0.000
D57.2 Double heterozygous sickling disorders	0.002	0.997	0.000
D57.1 Sickle-cell anaemia without crisis	0.002	0.997	0.000
D57.0 Sickle-cell anaemia with crisis	0.002	0.997	0.000
V20.4 Driver injured in traffic accident	0.003	0.997	0.000
Y44.2 Anticoagulants	0.003	0.997	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.003	0.997	0.000
Y82 Other and unspecified medical devices associated with adverse incidents	0.003	0.997	0.000
Y81 General- and plastic-surgery devices associated with adverse incidents	0.003	0.997	0.000
Y80 Physical medicine devices associated with adverse incidents	0.003	0.997	0.000
Y78 Radiological devices associated with adverse incidents	0.003	0.997	0.000
Y75 Neurological devices associated with adverse incidents	0.003	0.997	0.000
Y74 General hospital and personal-use devices associated with adverse incidents	0.003	0.997	0.000
Y72 Otorhinolaryngological devices associated with adverse incidents	0.003	0.997	0.000
Y71 Cardiovascular devices associated with adverse incidents	0.003	0.997	0.000
Y70 Anaesthesiology devices associated with adverse incidents	0.003	0.997	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.002	0.997	0.000
D58.2 Other haemoglobinopathies	0.002	0.997	0.000
D58.1 Hereditary elliptocytosis	0.002	0.997	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.000	0.997	0.003
Y46.8 Antispasticity drugs	0.003	0.997	0.000
Y46.7 Anti-Parkinsonism drugs	0.003	0.997	0.000
Y46.6 Other and unspecified antiepileptics	0.003	0.997	0.000
Y46.5 Valproic acid	0.003	0.997	0.000
Y46.4 Iminostilbenes	0.003	0.997	0.000
Y46.3 Deoxybarbiturates	0.003	0.997	0.000
Y46.1 Oxazolidinediones	0.003	0.997	0.000
Y46.0 Succinimides	0.003	0.997	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.003	0.997	0.000
Y28 Contact with sharp object, undetermined intent	0.003	0.997	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.002	0.997	0.000
K92.9 Disease of digestive system, unspecified	0.002	0.997	0.001
X68 Intentional self-poisoning by and exposure to pesticides	0.003	0.997	0.000
D58.0 Hereditary spherocytosis	0.002	0.997	0.000
D53.8 Other specified nutritional anaemias	0.002	0.997	0.000
D53.2 Scorbutic anaemia	0.002	0.997	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.002	0.997	0.000
D53.0 Protein deficiency anaemia	0.002	0.997	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.003	0.997	0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.003	0.997	0.000
W55 Bitten or struck by other mammals	0.003	0.997	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.002	0.997	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.002	0.997	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.002	0.997	0.000
Y47.4 Bromine compounds	0.002	0.997	0.000
Y47.3 Paraldehyde	0.002	0.997	0.000
Y47.2 Chloral derivatives	0.002	0.997	0.000
Y47.1 Benzodiazepines	0.002	0.997	0.000
Y47.0 Barbiturates, not elsewhere classified	0.002	0.997	0.000
Y50.9 Central nervous system stimulant, unspecified	0.002	0.997	0.000
Y50.8 Other central nervous system stimulants	0.002	0.997	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.997	0.000
Y50.1 Opioid receptor antagonists	0.002	0.997	0.000
Y50.0 Analeptics	0.002	0.997	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.997	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.002	0.997	0.000
Y55.5 Anticommon cold drugs	0.002	0.997	0.000
Y55.4 Expectorants	0.002	0.997	0.000
Y55.3 Antitussives	0.002	0.997	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.997	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.997	0.000
Y55.0 Oxytocic drugs	0.002	0.997	0.000
Y59.9 Vaccine or biological substance, unspecified	0.002	0.997	0.000
Y59.8 Other specified vaccines and biological substances	0.002	0.997	0.000
Y59.3 Immunoglobulin	0.002	0.997	0.000
Y59.2 Protozoal vaccines	0.002	0.997	0.000
Y59.1 Rickettsial vaccines	0.002	0.997	0.000
Y59.0 Viral vaccines	0.002	0.997	0.000
K31.8 Other specified diseases of stomach and duodenum	0.000	0.997	0.003
K91.0 Vomiting following gastro-intestinal surgery	0.002	0.997	0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.003	0.997	0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents	0.002	0.997	0.000
W57.0 Home	0.003	0.997	0.000
Y41.0 Sulphonamides	0.002	0.997	0.000
Y48.5 Therapeutic gases	0.002	0.997	0.000
Y48.4 Anaesthetic, unspecified	0.002	0.997	0.000
Y48.1 Parenteral anaesthetics	0.002	0.997	0.000
Y48.0 Inhaled anaesthetics	0.002	0.997	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.003	0.997	0.000
W46 Contact with hypodermic needle	0.003	0.997	0.000
W45 Foreign body or object entering through skin	0.003	0.997	0.000
W43 Exposure to vibration	0.003	0.997	0.000
W42 Exposure to noise	0.003	0.997	0.000
W41 Exposure to high-pressure jet	0.003	0.997	0.000
W40 Explosion of other materials	0.003	0.997	0.000
W39 Discharge of firework	0.003	0.997	0.000
W38 Explosion and rupture of other specified pressurised devices	0.003	0.997	0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.003	0.997	0.000
W36 Explosion and rupture of gas cylinder	0.003	0.997	0.000
W35 Explosion and rupture of boiler	0.003	0.997	0.000
W34 Discharge from other and unspecified firearms	0.003	0.997	0.000
W33 Rifle, shotgun and larger firearm discharge	0.003	0.997	0.000
W32 Handgun discharge	0.003	0.997	0.000
W31 Contact with other and unspecified machinery	0.003	0.997	0.000
W30 Contact with agricultural machinery	0.003	0.997	0.000
W28 Contact with powered lawn mower	0.003	0.997	0.000
W27 Contact with nonpowered hand tool	0.003	0.997	0.000
W26 Contact with knife, sword or dagger	0.003	0.997	0.000
W24 Contact with lifting and transmission devices, not elsewhere classified	0.003	0.997	0.000
W94 Exposure to high and low air pressure and changes in air pressure	0.002	0.997	0.000
V10-V19 Pedal cyclist injured in transport accident	0.003	0.997	0.000
W64 Exposure to other and unspecified animate mechanical forces	0.002	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations