TreeWAS – Variant ID: rs4782309

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I83.9 Varicose veins of lower extremities without ulcer or inflammation	1.000	0.000	0.000
I83 Varicose veins of lower extremities	0.955	0.045	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.898	0.102	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.892	0.108	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.747	0.253	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.101	0.899	0.000
I82 Other venous embolism and thrombosis	0.097	0.903	0.000
I82.8 Embolism and thrombosis of other specified veins	0.088	0.912	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.081	0.919	0.000
I85 Oesophageal varices	0.079	0.921	0.000
I82.2 Embolism and thrombosis of vena cava	0.078	0.922	0.000
I86 Varicose veins of other sites	0.074	0.926	0.000
I82.3 Embolism and thrombosis of renal vein	0.070	0.930	0.000
I82.1 Thrombophlebitis migrans	0.070	0.930	0.000
I82.0 Budd-Chiari syndrome	0.070	0.930	0.000
I88 Nonspecific lymphadenitis	0.069	0.930	0.000
I86.1 Scrotal varices	0.061	0.939	0.000
I81 Portal vein thrombosis	0.060	0.940	0.000
I85.9 Oesophageal varices without bleeding	0.060	0.940	0.000
I85.0 Oesophageal varices with bleeding	0.059	0.940	0.000
I86.2 Pelvic varices	0.058	0.942	0.000
I88.0 Nonspecific mesenteric lymphadenitis	0.054	0.946	0.000
I86.3 Vulval varices	0.053	0.946	0.000
I86.0 Sublingual varices	0.053	0.946	0.000
I88.8 Other nonspecific lymphadenitis	0.050	0.950	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.050	0.950	0.000
I86.8 Varicose veins of other specified sites	0.049	0.951	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.047	0.953	0.000
I87 Other disorders of veins	0.047	0.953	0.000
I86.4 Gastric varices	0.042	0.958	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.041	0.959	0.000
I80 Phlebitis and thrombophlebitis	0.040	0.960	0.000
I89.1 Lymphangitis	0.038	0.962	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.035	0.965	0.000
I87.9 Disorder of vein, unspecified	0.034	0.966	0.000
I87.0 Postphlebitic syndrome	0.034	0.966	0.000
M51.2 Other specified intervertebral disk displacement	0.000	0.966	0.034
I87.1 Compression of vein	0.032	0.968	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.032	0.968	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.031	0.969	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.029	0.971	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.029	0.971	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.028	0.972	0.000
M51 Other intervertebral disk disorders	0.000	0.975	0.025
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.000	0.975	0.025
I80.8 Phlebitis and thrombophlebitis of other sites	0.024	0.976	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.021	0.979	0.000
M51.8 Other specified intervertebral disk disorders	0.000	0.979	0.021
G57.6 Lesion of plantar nerve	0.000	0.980	0.020
I87.8 Other specified disorders of veins	0.019	0.980	0.000
M51.3 Other specified intervertebral disk degeneration	0.000	0.981	0.018
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.000	0.981	0.018
M51.4 Schmorl's nodes	0.000	0.982	0.018
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified	0.000	0.986	0.013
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region	0.000	0.986	0.013
M51.37 Other intervertebral disc degeneration, lumbosacral region	0.000	0.986	0.013
G99.2 Myelopathy in diseases classified elsewhere	0.000	0.987	0.013
M51.9 Intervertebral disk disorder, unspecified	0.000	0.988	0.012
I89.0 Lymphoedema, not elsewhere classified	0.011	0.989	0.001
O60-O75 Complications of labour and delivery	0.010	0.990	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.010	0.990	0.000
O62 Abnormalities of forces of labour	0.010	0.990	0.000
O75.8 Other specified complications of labour and delivery	0.010	0.990	0.000
O14.1 Severe preeclampsia	0.010	0.990	0.000
J32.9 Chronic sinusitis, unspecified	0.000	0.990	0.010
O69.2 Labour and delivery complicated by other cord entanglement	0.010	0.990	0.000
O62.3 Precipitate labour	0.009	0.990	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.000	0.991	0.009
O70.0 First degree perineal laceration during delivery	0.009	0.991	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.009	0.991	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.009	0.991	0.000
J32 Chronic sinusitis	0.000	0.991	0.009
O75.7 Vaginal delivery following previous Caesarean section	0.009	0.991	0.000
O71 Other obstetric trauma	0.009	0.991	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.009	0.991	0.000
O70 Perineal laceration during delivery	0.009	0.991	0.000
O62.1 Secondary uterine inertia	0.009	0.991	0.000
J32.2 Chronic ethmoidal sinusitis	0.000	0.991	0.009
O62.0 Primary inadequate contractions	0.008	0.992	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.008	0.992	0.000
J32.0 Chronic maxillary sinusitis	0.000	0.992	0.008
M13.94 Arthritis, unspecified (Hand)	0.008	0.992	0.000
O63 Long labour	0.008	0.992	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.008	0.992	0.000
O75.0 Maternal distress during labour and delivery	0.008	0.992	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.008	0.992	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.008	0.992	0.000
Y83.8 Other surgical procedures	0.000	0.992	0.008
O63.9 Long labour, unspecified	0.008	0.992	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.008	0.992	0.000
O72 Postpartum haemorrhage	0.008	0.992	0.000
O61 Failed induction of labour	0.008	0.992	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.000	0.992	0.008
O74 Complications of anaesthesia during labour and delivery	0.008	0.992	0.000
O60 Preterm delivery	0.008	0.992	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.008	0.992	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.008	0.992	0.000
O85-O92 Complications predominantly related to the puerperium	0.008	0.992	0.000
O62.9 Abnormality of forces of labour, unspecified	0.007	0.992	0.000
O62.8 Other abnormalities of forces of labour	0.007	0.992	0.000
O75.9 Complication of labour and delivery, unspecified	0.007	0.992	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.007	0.992	0.000
O75.4 Other complications of obstetric surgery and procedures	0.007	0.992	0.000
O75.3 Other infection during labour	0.007	0.992	0.000
O75.1 Shock during or following labour and delivery	0.007	0.992	0.000
O90 Complications of the puerperium, not elsewhere classified	0.008	0.992	0.000
J32.4 Chronic pansinusitis	0.000	0.992	0.007
O12.0 Gestational oedema	0.007	0.993	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O71.4 Obstetric high vaginal laceration alone	0.007	0.993	0.000
O71.5 Other obstetric injury to pelvic organs	0.007	0.993	0.000
O70.2 Third degree perineal laceration during delivery	0.007	0.993	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O14.9 Preeclampsia, unspecified	0.007	0.993	0.000
O14.0 Moderate preeclampsia	0.007	0.993	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.000	0.993	0.007
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.000	0.993	0.007
O12.2 Gestational oedema with proteinuria	0.007	0.993	0.000
O14.2 HELLP syndrome	0.007	0.993	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.007	0.993	0.000
O80-O84 Delivery	0.007	0.993	0.000
O90.0 Disruption of Caesarean section wound	0.007	0.993	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.007	0.993	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.007	0.993	0.000
O69.3 Labour and delivery complicated by short cord	0.007	0.993	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.007	0.993	0.000
O71.8 Other specified obstetric trauma	0.007	0.993	0.000
J32.3 Chronic sphenoidal sinusitis	0.000	0.993	0.007
O72.0 Third-stage haemorrhage	0.007	0.993	0.000
J32.1 Chronic frontal sinusitis	0.000	0.993	0.007
O67.9 Intrapartum haemorrhage, unspecified	0.007	0.993	0.000
O71.9 Obstetric trauma, unspecified	0.006	0.993	0.000
O71.7 Obstetric haematoma of pelvis	0.006	0.993	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.006	0.993	0.000
O71.3 Obstetric laceration of cervix	0.006	0.993	0.000
O71.2 Postpartum inversion of uterus	0.006	0.993	0.000
O71.1 Rupture of uterus during labour	0.006	0.993	0.000
O71.0 Rupture of uterus before onset of labour	0.006	0.993	0.000
O15 Eclampsia	0.007	0.993	0.000
O16 Unspecified maternal hypertension	0.007	0.993	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.007	0.993	0.000
O90.9 Complication of the puerperium, unspecified	0.007	0.993	0.000
J32.8 Other chronic sinusitis	0.000	0.993	0.007
O69.9 Labour and delivery complicated by cord complication, unspecified	0.006	0.993	0.000
C15.4 Middle third of oesophagus	0.007	0.993	0.000
O70.3 Fourth degree perineal laceration during delivery	0.006	0.993	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.006	0.993	0.000
S22.40 Multiple fractures of ribs (closed)	0.000	0.994	0.006
O62.2 Other uterine inertia	0.006	0.994	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.006	0.994	0.000
O61.1 Failed instrumental induction of labour	0.006	0.994	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.006	0.994	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.006	0.994	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.006	0.994	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O82 Single delivery by Caesarean section	0.006	0.994	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.006	0.994	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.006	0.994	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.006	0.994	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.006	0.994	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.006	0.994	0.000
O65.0 Obstructed labour due to deformed pelvis	0.006	0.994	0.000
O67.8 Other intrapartum haemorrhage	0.006	0.994	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.006	0.994	0.000
O69.8 Labour and delivery complicated by other cord complications	0.006	0.994	0.000
O73 Retained placenta and membranes, without haemorrhage	0.006	0.994	0.000
O12.1 Gestational proteinuria	0.006	0.994	0.000
O82.0 Delivery by elective Caesarean section	0.006	0.994	0.000
O89 Complications of anaesthesia during the puerperium	0.006	0.994	0.000
O90.2 Haematoma of obstetric wound	0.006	0.994	0.000
G90-G99 Other disorders of the nervous system	0.000	0.994	0.006
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.006	0.994	0.000
O72.3 Postpartum coagulation defects	0.006	0.994	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.006	0.994	0.000
O61.9 Failed induction of labour, unspecified	0.006	0.994	0.000
O61.8 Other failed induction of labour	0.006	0.994	0.000
O86 Other puerperal infections	0.006	0.994	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.994	0.006
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.994	0.006
O60.3 Preterm delivery without spontaneous labour	0.006	0.994	0.000
O60.2 Preterm spontaneous labour with term delivery	0.006	0.994	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.006	0.994	0.000
O60.0 Preterm labour without delivery	0.006	0.994	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.006	0.994	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.006	0.994	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.006	0.994	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.006	0.994	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.006	0.994	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.006	0.994	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.006	0.994	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.006	0.994	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.006	0.994	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.006	0.994	0.000
O91 Infections of breast associated with childbirth	0.006	0.994	0.000
O88 Obstetric embolism	0.006	0.994	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O97 Death from sequelae of direct obstetric causes	0.006	0.994	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.006	0.994	0.000
O95 Obstetric death of unspecified cause	0.006	0.994	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O90.5 Postpartum thyroiditis	0.006	0.994	0.000
O90.4 Postpartum acute renal failure	0.006	0.994	0.000
O90.3 Cardiomyopathy in the puerperium	0.006	0.994	0.000
O90.1 Disruption of perineal obstetric wound	0.006	0.994	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.006	0.994	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.006	0.994	0.000
O63.1 Prolonged second stage (of labour)	0.006	0.994	0.000
G90 Disorders of autonomic nervous system	0.000	0.994	0.006
O92 Other disorders of breast and lactation associated with childbirth	0.005	0.994	0.000
O61.0 Failed medical induction of labour	0.005	0.994	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.005	0.994	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.005	0.994	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.005	0.994	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.005	0.994	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.005	0.994	0.000
G96 Other disorders of central nervous system	0.000	0.994	0.005
G57 Mononeuropathies of lower limb	0.000	0.995	0.005
C15 Malignant neoplasm of oesophagus	0.005	0.995	0.000
O41 Other disorders of amniotic fluid and membranes	0.005	0.995	0.000
O00-O08 Pregnancy with abortive outcome	0.005	0.995	0.000
G90.2 Horner's syndrome	0.000	0.995	0.005
O70.9 Perineal laceration during delivery, unspecified	0.005	0.995	0.000
O84 Multiple delivery	0.005	0.995	0.000
O83 Other assisted single delivery	0.005	0.995	0.000
C15.9 Oesophagus, unspecified	0.005	0.995	0.000
O81 Single delivery by forceps and vacuum extractor	0.005	0.995	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.005	0.995	0.000
O87 Venous complications in the puerperium	0.005	0.995	0.000
G96.0 Cerebrospinal fluid leak	0.000	0.995	0.005
O43.8 Other placental disorders	0.005	0.995	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.995	0.005
C15.5 Lower third of oesophagus	0.005	0.995	0.000
O43 Placental disorders	0.005	0.995	0.000
O66 Other obstructed labour	0.005	0.995	0.000
S22.4 Multiple fractures of ribs	0.000	0.995	0.005
O85 Puerperal sepsis	0.005	0.995	0.000
O41.0 Oligohydramnios	0.005	0.995	0.000
O15.9 Eclampsia, unspecified as to time period	0.005	0.995	0.000
O15.2 Eclampsia in the puerperium	0.005	0.995	0.000
O15.1 Eclampsia in labour	0.005	0.995	0.000
O15.0 Eclampsia in pregnancy	0.005	0.995	0.000
O64.1 Obstructed labour due to breech presentation	0.005	0.995	0.000
O82.9 Delivery by Caesarean section, unspecified	0.005	0.995	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.005	0.995	0.000
N64.5 Other signs and symptoms in breast	0.000	0.995	0.005
G95 Other diseases of spinal cord	0.000	0.995	0.005
O32.8 Maternal care for other malpresentation of foetus	0.005	0.995	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.005	0.995	0.000
O80.9 Single spontaneous delivery, unspecified	0.005	0.995	0.000
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.005	0.995	0.000
O30 Multiple gestation	0.005	0.995	0.000
S22.0 Fracture of thoracic vertebra	0.000	0.995	0.005
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.005	0.995	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.005	0.995	0.000
O64.5 Obstructed labour due to compound presentation	0.005	0.995	0.000
O64.4 Obstructed labour due to shoulder presentation	0.005	0.995	0.000
O64.3 Obstructed labour due to brow presentation	0.005	0.995	0.000
O64.2 Obstructed labour due to face presentation	0.005	0.995	0.000
O80 Single spontaneous delivery	0.005	0.995	0.000
M50-M54 Other dorsopathies	0.000	0.995	0.005
O46 Antepartum haemorrhage, not elsewhere classified	0.005	0.995	0.000
O45 Premature separation of placenta [abruptio placentae]	0.005	0.995	0.000
O82.8 Other single delivery by Caesarean section	0.005	0.995	0.000
O82.2 Delivery by Caesarean hysterectomy	0.005	0.995	0.000
G91 Hydrocephalus	0.000	0.995	0.005
G90.0 Idiopathic peripheral autonomic neuropathy	0.000	0.995	0.005
O86.1 Other infection of genital tract following delivery	0.005	0.995	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.995	0.005
O72.1 Other immediate postpartum haemorrhage	0.005	0.995	0.000
O00 Ectopic pregnancy	0.005	0.995	0.000
G95.1 Vascular myelopathies	0.000	0.995	0.005
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.000	0.995	0.005
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.995	0.005
O41.8 Other specified disorders of amniotic fluid and membranes	0.005	0.995	0.000
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.004	0.995	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.004	0.995	0.000
O89.6 Failed or difficult intubation during the puerperium	0.004	0.995	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.004	0.995	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.004	0.995	0.000
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.004	0.995	0.000
O89.1 Cardiac complications of anaesthesia during the puerperium	0.004	0.995	0.000
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.004	0.995	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.004	0.995	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.000	0.995	0.004
G92 Toxic encephalopathy	0.000	0.995	0.004
O86.2 Urinary tract infection following delivery	0.004	0.995	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O63.0 Prolonged first stage (of labour)	0.004	0.996	0.000
O86.8 Other specified puerperal infections	0.004	0.996	0.000
O86.3 Other genito-urinary tract infections following delivery	0.004	0.996	0.000
O81.0 Low forceps delivery	0.004	0.996	0.000
O86.4 Pyrexia of unknown origin following delivery	0.004	0.996	0.000
O96.9 Death from unspecified obstetric cause	0.004	0.996	0.000
O96.1 Death from indirect obstetric cause	0.004	0.996	0.000
O96.0 Death from direct obstetric cause	0.004	0.996	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.004	0.996	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.004	0.996	0.000
O97.0 Death from sequelae of direct obstetric cause	0.004	0.996	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O00.1 Tubal pregnancy	0.004	0.996	0.000
O88.8 Other obstetric embolism	0.004	0.996	0.000
O88.3 Obstetric pyaemic and septic embolism	0.004	0.996	0.000
O88.2 Obstetric blood-clot embolism	0.004	0.996	0.000
O88.1 Amniotic fluid embolism	0.004	0.996	0.000
O88.0 Obstetric air embolism	0.004	0.996	0.000
O91.2 Nonpurulent mastitis associated with childbirth	0.004	0.996	0.000
O91.1 Abscess of breast associated with childbirth	0.004	0.996	0.000
O91.0 Infection of nipple associated with childbirth	0.004	0.996	0.000
O48 Prolonged pregnancy	0.004	0.996	0.000
O33 Maternal care for known or suspected disproportion	0.004	0.996	0.000
O81.3 Other and unspecified forceps delivery	0.004	0.996	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O31 Complications specific to multiple gestation	0.004	0.996	0.000
O30.1 Triplet pregnancy	0.004	0.996	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.000	0.996	0.004
O92.7 Other and unspecified disorders of lactation	0.004	0.996	0.000
O92.6 Galactorrhoea	0.004	0.996	0.000
O92.5 Suppressed lactation	0.004	0.996	0.000
O92.4 Hypogalactia	0.004	0.996	0.000
O92.3 Agalactia	0.004	0.996	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.004	0.996	0.000
O92.0 Retracted nipple associated with childbirth	0.004	0.996	0.000
G90.8 Other disorders of autonomic nervous system	0.000	0.996	0.004
G90.4 Autonomic dysreflexia	0.000	0.996	0.004
G90.1 Familial dysautonomia [Riley-Day]	0.000	0.996	0.004
G57.5 Tarsal tunnel syndrome	0.000	0.996	0.004
M06.9 Rheumatoid arthritis, unspecified	0.000	0.996	0.004
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.000	0.996	0.004
O02 Other abnormal products of conception	0.004	0.996	0.000
G90.3 Multisystem degeneration	0.000	0.996	0.004
G96.9 Disorder of central nervous system, unspecified	0.000	0.996	0.004
G96.8 Other specified disorders of central nervous system	0.000	0.996	0.004
O32.9 Maternal care for malpresentation of foetus, unspecified	0.004	0.996	0.000
G57.9 Mononeuropathy of lower limb, unspecified	0.000	0.996	0.004
G57.4 Lesion of medial popliteal nerve	0.000	0.996	0.004
G57.2 Lesion of femoral nerve	0.000	0.996	0.004
G57.0 Lesion of sciatic nerve	0.000	0.996	0.004
C15.8 Overlapping lesion of oesophagus	0.004	0.996	0.000
C15.2 Abdominal part of oesophagus	0.004	0.996	0.000
C15.1 Thoracic part of oesophagus	0.004	0.996	0.000
C15.0 Cervical part of oesophagus	0.004	0.996	0.000
G57.8 Other mononeuropathies of lower limb	0.000	0.996	0.004
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.004	0.996	0.000
O41.1 Infection of amniotic sac and membranes	0.004	0.996	0.000
O92.1 Cracked nipple associated with childbirth	0.004	0.996	0.000
O07 Failed attempted abortion	0.004	0.996	0.000
O06 Unspecified abortion	0.004	0.996	0.000
O05 Other abortion	0.004	0.996	0.000
O01 Hydatidiform mole	0.004	0.996	0.000
O86.0 Infection of obstetric surgical wound	0.004	0.996	0.000
G91.1 Obstructive hydrocephalus	0.000	0.996	0.004
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.996	0.004
X49.9 Unspecified place	0.004	0.996	0.000
N64 Other disorders of breast	0.000	0.996	0.004
O83.9 Assisted single delivery, unspecified	0.004	0.996	0.000
O83.8 Other specified assisted single delivery	0.004	0.996	0.000
O83.4 Destructive operation for delivery	0.004	0.996	0.000
O83.3 Delivery of viable foetus in abdominal pregnancy	0.004	0.996	0.000
O83.2 Other manipulation-assisted delivery	0.004	0.996	0.000
O83.1 Other assisted breech delivery	0.004	0.996	0.000
O83.0 Breech extraction	0.004	0.996	0.000
O84.9 Multiple delivery, unspecified	0.004	0.996	0.000
O84.8 Other multiple delivery	0.004	0.996	0.000
O84.2 Multiple delivery, all by Caesarean section	0.004	0.996	0.000
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.004	0.996	0.000
O84.0 Multiple delivery, all spontaneous	0.004	0.996	0.000
O45.9 Premature separation of placenta, unspecified	0.004	0.996	0.000
O81.5 Delivery by combination of forceps and vacuum extractor	0.004	0.996	0.000
O81.2 Mid-cavity forceps with rotation	0.004	0.996	0.000
O81.1 Mid-cavity forceps delivery	0.004	0.996	0.000
O32.0 Maternal care for unstable lie	0.004	0.996	0.000
O46.8 Other antepartum haemorrhage	0.004	0.996	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.996	0.004
M43.16 Spondylolisthesis (Lumbar region)	0.000	0.996	0.004
G90.9 Disorder of autonomic nervous system, unspecified	0.000	0.996	0.004
O87.9 Venous complication in the puerperium, unspecified	0.004	0.996	0.000
O87.8 Other venous complications in the puerperium	0.004	0.996	0.000
O87.3 Cerebral venous thrombosis in the puerperium	0.004	0.996	0.000
O87.1 Deep phlebothrombosis in the puerperium	0.004	0.996	0.000
O87.0 Superficial thrombophlebitis in the puerperium	0.004	0.996	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.004	0.996	0.000
O03 Spontaneous abortion	0.004	0.996	0.000
C15.3 Upper third of oesophagus	0.004	0.996	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.004	0.996	0.000
O43.9 Placental disorder, unspecified	0.004	0.996	0.000
O43.2 Morbidly adherent placenta	0.004	0.996	0.000
O43.0 Placental transfusion syndromes	0.004	0.996	0.000
O66.9 Obstructed labour, unspecified	0.004	0.996	0.000
O66.8 Other specified obstructed labour	0.004	0.996	0.000
O66.4 Failed trial of labour, unspecified	0.004	0.996	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.004	0.996	0.000
O66.2 Obstructed labour due to unusually large foetus	0.004	0.996	0.000
O66.1 Obstructed labour due to locked twins	0.004	0.996	0.000
S22.41 Multiple fractures of ribs (open)	0.000	0.996	0.004
G95.8 Other specified diseases of spinal cord	0.000	0.996	0.004
L28.0 Lichen simplex chronicus	0.004	0.996	0.000
N36.2 Urethral caruncle	0.004	0.996	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.004	0.996	0.000
S19.9 Unspecified injury of neck	0.004	0.996	0.000
G97.8 Other postprocedural disorders of nervous system	0.000	0.996	0.004
R27.0 Ataxia, unspecified	0.000	0.996	0.004
S72.00 Fracture of neck of femur (closed)	0.000	0.996	0.004
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O32.2 Maternal care for transverse and oblique lie	0.004	0.996	0.000
O32.6 Maternal care for compound presentation	0.004	0.996	0.000
N64.9 Disorder of breast, unspecified	0.000	0.996	0.004
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.004	0.996	0.000
O34.6 Maternal care for abnormality of vagina	0.004	0.996	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.004	0.996	0.000
O34.0 Maternal care for congenital malformation of uterus	0.004	0.996	0.000
G91.2 Normal-pressure hydrocephalus	0.000	0.996	0.004
O03.9 Complete or unspecified, without complication	0.004	0.996	0.000
O30.9 Multiple gestation, unspecified	0.004	0.996	0.000
O30.8 Other multiple gestation	0.004	0.996	0.000
O30.2 Quadruplet pregnancy	0.004	0.996	0.000
S22.01 Fracture of thoracic vertebra (open)	0.000	0.996	0.004
G97.0 Cerebrospinal fluid leak from spinal puncture	0.000	0.996	0.004
G91.9 Hydrocephalus, unspecified	0.000	0.996	0.004
G57.1 Meralgia paraesthetica	0.000	0.996	0.004
O80.1 Spontaneous breech delivery	0.003	0.996	0.000
O34.4 Maternal care for other abnormalities of cervix	0.004	0.996	0.000
O32.4 Maternal care for high head at term	0.004	0.996	0.000
O45.8 Other premature separation of placenta	0.003	0.996	0.000
O45.0 Premature separation of placenta with coagulation defect	0.003	0.996	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.004	0.996	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.000	0.996	0.003
O82.1 Delivery by emergency Caesarean section	0.003	0.996	0.000
O46.9 Antepartum haemorrhage, unspecified	0.004	0.996	0.000
O00.8 Other ectopic pregnancy	0.003	0.996	0.000
O00.2 Ovarian pregnancy	0.003	0.996	0.000
O00.0 Abdominal pregnancy	0.003	0.996	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.000	0.996	0.003
G97.2 Intracranial hypotension following ventricular shunting	0.000	0.996	0.003
O30.0 Twin pregnancy	0.004	0.996	0.000
G95.2 Cord compression, unspecified	0.000	0.996	0.004
O44 Placenta praevia	0.003	0.996	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.996	0.003
O32.3 Maternal care for face, brow and chin presentation	0.003	0.996	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.996	0.003
O02.1 Missed abortion	0.004	0.996	0.000
G95.0 Syringomyelia and syringobulbia	0.000	0.997	0.003
O34.3 Maternal care for cervical incompetence	0.003	0.997	0.000
O87.2 Haemorrhoids in the puerperium	0.003	0.997	0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.003	0.997	0.000
M50 Cervical disk disorders	0.000	0.997	0.003
N63 Unspecified lump in breast	0.000	0.997	0.003
O47 False labour	0.003	0.997	0.000
O31.8 Other complications specific to multiple gestation	0.003	0.997	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.003	0.997	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.003	0.997	0.000
O31.0 Papyraceous foetus	0.003	0.997	0.000
O33.9 Maternal care for disproportion, unspecified	0.003	0.997	0.000
O33.8 Maternal care for disproportion of other origin	0.003	0.997	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.003	0.997	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.003	0.997	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.003	0.997	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.003	0.997	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.003	0.997	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.003	0.997	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.003	0.997	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.003	0.997	0.000
G94.2 Hydrocephalus in other diseases classified elsewhere	0.000	0.997	0.003
G95.9 Disease of spinal cord, unspecified	0.000	0.997	0.003
G91.8 Other hydrocephalus	0.000	0.997	0.003
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.997	0.003
O43.1 Malformation of placenta	0.003	0.997	0.000
M53 Other dorsopathies, not elsewhere classified	0.000	0.997	0.003
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.000	0.997	0.003
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.000	0.997	0.003
O02.9 Abnormal product of conception, unspecified	0.003	0.997	0.000
O02.8 Other specified abnormal products of conception	0.003	0.997	0.000
O40 Polyhydramnios	0.003	0.997	0.000
G57.3 Lesion of lateral popliteal nerve	0.000	0.997	0.003
N61 Inflammatory disorders of breast	0.000	0.997	0.003
O73.0 Retained placenta, without haemorrhage	0.003	0.997	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.003	0.997	0.000
G91.0 Communicating hydrocephalus	0.000	0.997	0.003
O01.9 Hydatidiform mole, unspecified	0.003	0.997	0.000
O01.1 Incomplete and partial hydatidiform mole	0.003	0.997	0.000
O01.0 Classical hydatidiform mole	0.003	0.997	0.000
O05.9 Complete or unspecified, without complication	0.003	0.997	0.000
O05.8 Complete or unspecified, with other and unspecified complications	0.003	0.997	0.000
O05.7 Complete or unspecified, complicated by embolism	0.003	0.997	0.000
O05.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.003	0.997	0.000
O05.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.003	0.997	0.000
O05.4 Incomplete, without complication	0.003	0.997	0.000
O05.3 Incomplete, with other and unspecified complications	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations