TreeWAS – Variant ID: rs479844

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I12.0 Hypertensive renal disease with renal failure	0.542	0.458	0.000
I12 Hypertensive renal disease	0.532	0.468	0.000
I12.9 Hypertensive renal disease without renal failure	0.498	0.502	0.000
I10-I15 Hypertensive diseases	0.496	0.504	0.000
I10 Essential (primary) hypertension	0.489	0.511	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.387	0.613	0.000
I15 Secondary hypertension	0.380	0.620	0.000
I13 Hypertensive heart and renal disease	0.342	0.658	0.000
I11 Hypertensive heart disease	0.325	0.675	0.000
J45.9 Asthma, unspecified	0.308	0.692	0.000
I15.0 Renovascular hypertension	0.292	0.708	0.000
I15.8 Other secondary hypertension	0.292	0.708	0.000
I15.9 Seconday hypertension, unspecified	0.276	0.724	0.000
I15.2 Hypertension secondary to endocrine disorders	0.273	0.727	0.000
I15.1 Hypertension secondary to other renal disorders	0.252	0.748	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.245	0.755	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.245	0.755	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.242	0.758	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.236	0.764	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.235	0.765	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.198	0.801	0.000
I60-I69 Cerebrovascular diseases	0.100	0.900	0.000
Chapter IX Diseases of the circulatory system	0.099	0.901	0.000
I69 Sequelae of cerebrovascular disease	0.097	0.903	0.000
I61 Intracerebral haemorrhage	0.097	0.903	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.097	0.903	0.000
I60 Subarachnoid haemorrhage	0.096	0.904	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.094	0.906	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.092	0.908	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.091	0.909	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.088	0.912	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.085	0.915	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.082	0.918	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.082	0.918	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.079	0.921	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.079	0.921	0.000
I00-I02 Acute rheumatic fever	0.079	0.921	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.078	0.922	0.000
I61.8 Other intracerebral haemorrhage	0.078	0.922	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.074	0.926	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.073	0.927	0.000
I99 Other and unspecified disorders of circulatory system	0.073	0.927	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.072	0.928	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.071	0.929	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.071	0.929	0.000
I62 Other nontraumatic intracranial haemorrhage	0.071	0.929	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.070	0.929	0.000
I72 Other aneurysm	0.071	0.929	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.070	0.930	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.069	0.931	0.000
I70 Atherosclerosis	0.067	0.933	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.065	0.935	0.000
I78 Diseases of capillaries	0.065	0.935	0.000
I72.8 Aneurysm of other specified arteries	0.065	0.935	0.000
I00 Rheumatic fever without mention of heart involvement	0.064	0.936	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.063	0.937	0.000
I26 Pulmonary embolism	0.063	0.937	0.000
I67 Other cerebrovascular diseases	0.063	0.937	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.062	0.938	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.062	0.938	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.062	0.938	0.000
I74 Arterial embolism and thrombosis	0.061	0.939	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.060	0.940	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.060	0.940	0.000
I72.1 Aneurysm of artery of upper extremity	0.058	0.941	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.058	0.942	0.000
I71 Aortic aneurysm and dissection	0.057	0.943	0.000
I02 Rheumatic chorea	0.056	0.943	0.000
I01 Rheumatic fever with heart involvement	0.056	0.943	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.056	0.944	0.000
I68.0 Cerebral amyloid angiopathy	0.056	0.944	0.000
I67.1 Cerebral aneurysm, nonruptured	0.056	0.944	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.055	0.945	0.000
I69.3 Sequelae of cerebral infarction	0.055	0.945	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.055	0.945	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.055	0.945	0.000
I72.2 Aneurysm of renal artery	0.054	0.946	0.000
I78.1 Naevus, nonneoplastic	0.054	0.946	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.053	0.947	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.053	0.947	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.053	0.947	0.000
I62.1 Nontraumatic extradural haemorrhage	0.053	0.947	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.053	0.947	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.053	0.947	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.052	0.948	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.052	0.948	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.052	0.948	0.000
I28 Other diseases of pulmonary vessels	0.052	0.948	0.000
I67.4 Hypertensive encephalopathy	0.052	0.948	0.000
I67.8 Other specified cerebrovascular diseases	0.052	0.948	0.000
I72.9 Aneurysm of unspecified site	0.052	0.948	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.051	0.949	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.051	0.949	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.050	0.950	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.050	0.950	0.000
I97.1 Other functional disturbances following cardiac surgery	0.049	0.951	0.000
I70.1 Atherosclerosis of renal artery	0.049	0.951	0.000
I63 Cerebral infarction	0.049	0.951	0.000
I72.0 Aneurysm of carotid artery	0.049	0.951	0.000
J45 Asthma	0.049	0.951	0.000
I72.3 Aneurysm of iliac artery	0.048	0.952	0.000
I71.0 Dissection of aorta [any part]	0.048	0.952	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.047	0.952	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.047	0.953	0.000
I63.8 Other cerebral infarction	0.047	0.953	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.047	0.953	0.000
I70.9 Generalised and unspecified atherosclerosis	0.047	0.953	0.000
I97.0 Postcardiotomy syndrome	0.047	0.953	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.047	0.953	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.046	0.953	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.046	0.954	0.000
I78.9 Disease of capillaries, unspecified	0.046	0.954	0.000
I74.5 Embolism and thrombosis of iliac artery	0.046	0.954	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.046	0.954	0.000
I78.8 Other diseases of capillaries	0.045	0.955	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.045	0.955	0.000
I70.8 Atherosclerosis of other arteries	0.045	0.955	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.045	0.955	0.000
I67.5 Moyamoya disease	0.045	0.955	0.000
I67.3 Progressive vascular leukoencephalopathy	0.045	0.955	0.000
I79.1 Aortitis in diseases classified elsewhere	0.045	0.955	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.045	0.955	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.044	0.955	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.044	0.955	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.044	0.955	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.045	0.955	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.043	0.956	0.000
I74.8 Embolism and thrombosis of other arteries	0.044	0.956	0.000
I60.8 Other subarachnoid haemorrhage	0.043	0.956	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.043	0.957	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.042	0.958	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.042	0.958	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.041	0.958	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.041	0.959	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.041	0.959	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.041	0.959	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.041	0.959	0.000
I01.8 Other acute rheumatic heart disease	0.041	0.959	0.000
I01.2 Acute rheumatic myocarditis	0.041	0.959	0.000
I01.1 Acute rheumatic endocarditis	0.041	0.959	0.000
I01.0 Acute rheumatic pericarditis	0.041	0.959	0.000
I02.9 Rheumatic chorea without heart involvement	0.041	0.959	0.000
I02.0 Rheumatic chorea with heart involvement	0.041	0.959	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.040	0.960	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.039	0.961	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.039	0.961	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.038	0.962	0.000
I70.0 Atherosclerosis of aorta	0.038	0.962	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.037	0.962	0.000
I28.1 Aneurysm of pulmonary artery	0.037	0.963	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.037	0.963	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.037	0.963	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.037	0.963	0.000
I98.0 Cardiovascular syphilis	0.037	0.963	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.037	0.963	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.036	0.964	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.036	0.964	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.035	0.964	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.035	0.964	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.035	0.964	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.035	0.965	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.034	0.966	0.000
J45.1 Nonallergic asthma	0.033	0.966	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.033	0.967	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.033	0.967	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.032	0.967	0.000
J45.8 Mixed asthma	0.032	0.968	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.032	0.968	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.032	0.968	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.031	0.968	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.031	0.969	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.030	0.969	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.030	0.970	0.000
I28.8 Other specified diseases of pulmonary vessels	0.029	0.970	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.029	0.970	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.029	0.971	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.029	0.971	0.000
I27 Other pulmonary heart diseases	0.028	0.972	0.000
I72.4 Aneurysm of artery of lower extremity	0.027	0.972	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.027	0.972	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.027	0.973	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.974	0.026
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.025	0.975	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.024	0.976	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.977	0.023
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.977	0.023
I27.9 Pulmonary heart disease, unspecified	0.022	0.978	0.000
I73 Other peripheral vascular diseases	0.022	0.978	0.000
I65.1 Occlusion and stenosis of basilar artery	0.021	0.979	0.000
I27.1 Kyphoscoliotic heart disease	0.020	0.980	0.000
C34.3 Lower lobe, bronchus or lung	0.000	0.981	0.019
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.019	0.981	0.000
I05-I09 Chronic rheumatic heart diseases	0.018	0.982	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.982	0.018
K63.1 Perforation of intestine (nontraumatic)	0.018	0.982	0.000
I65.2 Occlusion and stenosis of carotid artery	0.018	0.982	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.982	0.018
I70.00 Atherosclerosis of aorta (without gangrene)	0.017	0.983	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.017	0.983	0.000
I77 Other disorders of arteries and arterioles	0.017	0.983	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.983	0.017
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.983	0.017
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.984	0.016
I27.0 Primary pulmonary hypertension	0.016	0.984	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.016	0.984	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.984	0.016
D61.9 Aplastic anaemia, unspecified	0.016	0.984	0.000
I73.8 Other specified peripheral vascular diseases	0.015	0.985	0.000
I09 Other rheumatic heart diseases	0.015	0.985	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.985	0.014
I20-I25 Ischaemic heart diseases	0.014	0.986	0.000
Z95.1 Presence of aortocoronary bypass graft	0.014	0.986	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.986	0.013
I24 Other acute ischaemic heart diseases	0.013	0.987	0.000
I24.8 Other forms of acute ischaemic heart disease	0.013	0.987	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.013	0.987	0.000
I77.0 Arteriovenous fistula, acquired	0.013	0.987	0.000
I27.8 Other specified pulmonary heart diseases	0.012	0.987	0.000
I06 Rheumatic aortic valve diseases	0.013	0.987	0.000
I77.5 Necrosis of artery	0.012	0.988	0.000
I77.4 Coeliac artery compression syndrome	0.012	0.988	0.000
I27.2 Other secondary pulmonary hypertension	0.012	0.988	0.000
I09.9 Rheumatic heart disease, unspecified	0.012	0.988	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.012	0.988	0.000
I77.3 Arterial fibromuscular dysplasia	0.012	0.988	0.000
K63.8 Other specified diseases of intestine	0.012	0.988	0.000
I24.1 Dressler's syndrome	0.011	0.989	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.011	0.989	0.000
L81.4 Other melanin hyperpigmentation	0.000	0.989	0.011
C71.9 Brain, unspecified	0.011	0.989	0.000
I09.8 Other specified rheumatic heart diseases	0.011	0.989	0.000
I09.2 Chronic rheumatic pericarditis	0.011	0.989	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.011	0.989	0.000
I09.0 Rheumatic myocarditis	0.011	0.989	0.000
I77.2 Rupture of artery	0.011	0.989	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.010	0.990	0.000
I23 Certain current complications following acute myocardial infarction	0.010	0.990	0.000
C71 Malignant neoplasm of brain	0.010	0.990	0.000
I77.8 Other specified disorders of arteries and arterioles	0.010	0.990	0.000
R06.0 Dyspnoea	0.010	0.990	0.000
C71.3 Parietal lobe	0.010	0.990	0.000
I06.1 Rheumatic aortic insufficiency	0.010	0.990	0.000
Q23.1 Congenital insufficiency of aortic valve	0.010	0.990	0.000
C71.1 Frontal lobe	0.010	0.990	0.000
J45.0 Predominantly allergic asthma	0.009	0.990	0.000
M13.99 Arthritis, unspecified (Site unspecified)	0.009	0.991	0.000
I95 Hypotension	0.009	0.991	0.000
I06.8 Other rheumatic aortic valve diseases	0.009	0.991	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.009	0.991	0.000
I07 Rheumatic tricuspid valve diseases	0.009	0.991	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.009	0.991	0.000
C71.0 Cerebrum, except lobes and ventricles	0.009	0.991	0.000
K63 Other diseases of intestine	0.009	0.991	0.000
I67.2 Cerebral atherosclerosis	0.005	0.991	0.004
I77.1 Stricture of artery	0.009	0.991	0.000
K63.0 Abscess of intestine	0.009	0.991	0.000
D25.2 Subserosal leiomyoma of uterus	0.000	0.991	0.009
I06.0 Rheumatic aortic stenosis	0.008	0.992	0.000
I95.2 Hypotension due to drugs	0.008	0.992	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.007	0.992	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.007	0.992	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.007	0.992	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.007	0.992	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.007	0.992	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.007	0.992	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.007	0.992	0.000
C71.6 Cerebellum	0.007	0.992	0.000
I23.8 Other current complications following acute myocardial infarction	0.007	0.992	0.000
C71.7 Brain stem	0.007	0.993	0.000
D32.9 Meninges, unspecified	0.007	0.993	0.000
C71.8 Overlapping lesion of brain	0.007	0.993	0.000
Q21.1 Atrial septal defect	0.000	0.993	0.007
K63.4 Enteroptosis	0.007	0.993	0.000
M05 Seropositive rheumatoid arthritis	0.000	0.993	0.007
I07.9 Tricuspid valve disease, unspecified	0.007	0.993	0.000
I07.8 Other tricuspid valve diseases	0.007	0.993	0.000
I07.2 Tricuspid stenosis with insufficiency	0.007	0.993	0.000
I07.0 Tricuspid stenosis	0.007	0.993	0.000
C71.5 Cerebral ventricle	0.007	0.993	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.007	0.993	0.000
C71.4 Occipital lobe	0.006	0.994	0.000
I77.6 Arteritis, unspecified	0.006	0.994	0.000
I21 Acute myocardial infarction	0.006	0.994	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.006	0.994	0.000
I21.4 Acute subendocardial myocardial infarction	0.006	0.994	0.000
C71.2 Temporal lobe	0.006	0.994	0.000
Q23 Congenital malformations of aortic and mitral valves	0.006	0.994	0.000
D32.0 Cerebral meninges	0.006	0.994	0.000
D32 Benign neoplasm of meninges	0.006	0.994	0.000
I67.9 Cerebrovascular disease, unspecified	0.006	0.994	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.000	0.994	0.006
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.995	0.005
I95.0 Idiopathic hypotension	0.005	0.995	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.995	0.005
M05.0 Felty's syndrome	0.000	0.995	0.005
M05.1 Rheumatoid lung disease	0.000	0.995	0.005
I73.0 Raynaud's syndrome	0.005	0.995	0.000
M05.8 Other seropositive rheumatoid arthritis	0.000	0.995	0.005
I24.9 Acute ischaemic heart disease, unspecified	0.005	0.995	0.000
D32.1 Spinal meninges	0.005	0.995	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.005	0.995	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.005	0.995	0.000
M05.2 Rheumatoid vasculitis	0.000	0.995	0.004
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.004	0.995	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.004	0.995	0.000
Q23.4 Hypoplastic left heart syndrome	0.004	0.995	0.000
Q23.2 Congenital mitral stenosis	0.004	0.995	0.000
Q27 Other congenital malformations of peripheral vascular system	0.004	0.995	0.000
N76.4 Abscess of vulva	0.005	0.995	0.000
Q28 Other congenital malformations of circulatory system	0.004	0.995	0.000
C34 Malignant neoplasm of bronchus and lung	0.000	0.995	0.005
D61 Other aplastic anaemias	0.004	0.996	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.004	0.996	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.000	0.996	0.004
C34.0 Main bronchus	0.000	0.996	0.004
Z95.2 Presence of prosthetic heart valve	0.004	0.996	0.000
K63.2 Fistula of intestine	0.004	0.996	0.000
I05 Rheumatic mitral valve diseases	0.004	0.996	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.004	0.996	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.004	0.996	0.000
N76.2 Acute vulvitis	0.004	0.996	0.000
Q23.3 Congenital mitral insufficiency	0.004	0.996	0.000
I95.8 Other hypotension	0.004	0.996	0.000
Z95.4 Presence of other heart-valve replacement	0.004	0.996	0.000
M05.09 Felty's syndrome (Site unspecified)	0.000	0.996	0.004
M05.08 Felty's syndrome (Other)	0.000	0.996	0.004
M05.07 Felty's syndrome (Ankle and foot)	0.000	0.996	0.004
M05.06 Felty's syndrome (Lower leg)	0.000	0.996	0.004
M05.05 Felty's syndrome (Pelvic region and thigh)	0.000	0.996	0.004
M05.04 Felty's syndrome (Hand)	0.000	0.996	0.004
M05.03 Felty's syndrome (Forearm)	0.000	0.996	0.004
M05.02 Felty's syndrome (Upper arm)	0.000	0.996	0.004
M05.01 Felty's syndrome (Shoulder region)	0.000	0.996	0.004
M05.00 Felty's syndrome (Multiple sites)	0.000	0.996	0.004
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.000	0.996	0.004
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.000	0.996	0.004
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.000	0.996	0.004
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.000	0.996	0.004
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.000	0.996	0.004
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.000	0.996	0.004
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.000	0.996	0.004
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.000	0.996	0.004
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.000	0.996	0.004
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.000	0.996	0.004
I49.8 Other specified cardiac arrhythmias	0.000	0.996	0.004
L81 Other disorders of pigmentation	0.000	0.996	0.004
Q27.8 Other specified congenital malformations of peripheral vascular system	0.004	0.996	0.000
M05.18 Rheumatoid lung disease (Other)	0.000	0.996	0.004
M05.17 Rheumatoid lung disease (Ankle and foot)	0.000	0.996	0.004
M05.16 Rheumatoid lung disease (Lower leg)	0.000	0.996	0.004
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.000	0.996	0.004
M05.14 Rheumatoid lung disease (Hand)	0.000	0.996	0.004
M05.13 Rheumatoid lung disease (Forearm)	0.000	0.996	0.004
M05.12 Rheumatoid lung disease (Upper arm)	0.000	0.996	0.004
M05.11 Rheumatoid lung disease (Shoulder region)	0.000	0.996	0.004
Q21 Congenital malformations of cardiac septa	0.002	0.996	0.002
C34.2 Middle lobe, bronchus or lung	0.000	0.996	0.004
I08 Multiple valve diseases	0.004	0.996	0.000
C25.0 Head of pancreas	0.004	0.996	0.000
N76 Other inflammation of vagina and vulva	0.004	0.996	0.000
Z95.3 Presence of xenogenic heart valve	0.004	0.996	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.000	0.996	0.004
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.000	0.996	0.004
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.000	0.996	0.004
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.000	0.996	0.004
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.000	0.996	0.004
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.000	0.996	0.004
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.000	0.996	0.004
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.000	0.996	0.004
I73.9 Peripheral vascular disease, unspecified	0.004	0.996	0.000
Q22.5 Ebstein's anomaly	0.004	0.996	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.000	0.996	0.003
L81.2 Freckles	0.000	0.996	0.004
Q28.0 Arteriovenous malformation of precerebral vessels	0.004	0.996	0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.000	0.996	0.004
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.000	0.996	0.004
I25.2 Old myocardial infarction	0.004	0.996	0.000
Q23.0 Congenital stenosis of aortic valve	0.003	0.996	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.003	0.996	0.000
I25 Chronic ischaemic heart disease	0.004	0.996	0.000
Q26 Congenital malformations of great veins	0.003	0.996	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.003	0.996	0.000
C34.8 Overlapping lesion of bronchus and lung	0.000	0.996	0.004
M05.28 Rheumatoid vasculitis (Other)	0.000	0.996	0.003
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.000	0.996	0.003
M05.26 Rheumatoid vasculitis (Lower leg)	0.000	0.996	0.003
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.000	0.996	0.003
M05.24 Rheumatoid vasculitis (Hand)	0.000	0.996	0.003
M05.23 Rheumatoid vasculitis (Forearm)	0.000	0.996	0.003
M05.22 Rheumatoid vasculitis (Upper arm)	0.000	0.996	0.003
M05.21 Rheumatoid vasculitis (Shoulder region)	0.000	0.996	0.003
N76.3 Subacute and chronic vulvitis	0.004	0.996	0.000
I08.9 Multiple valve disease, unspecified	0.003	0.996	0.000
Q27.4 Congenital phlebectasia	0.003	0.996	0.000
Q27.2 Other congenital malformations of renal artery	0.003	0.996	0.000
Q27.1 Congenital renal artery stenosis	0.003	0.996	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.003	0.996	0.000
Q28.3 Other malformations of cerebral vessels	0.003	0.996	0.000
R86.8 Other abnormal findings	0.004	0.996	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.000	0.996	0.003
Q27.3 Peripheral arteriovenous malformation	0.003	0.996	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.003	0.996	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.003	0.996	0.000
Q28.1 Other malformations of precerebral vessels	0.003	0.996	0.000
R00.1 Bradycardia, unspecified	0.004	0.996	0.000
T17.2 Foreign body in pharynx	0.000	0.996	0.004
D61.8 Other specified aplastic anaemias	0.003	0.997	0.000
D61.3 Idiopathic aplastic anaemia	0.003	0.997	0.000
D61.2 Aplastic anaemia due to other external agents	0.003	0.997	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.000	0.997	0.003
N76.1 Subacute and chronic vaginitis	0.003	0.997	0.000
R84.5 Abnormal microbiological findings	0.003	0.997	0.000
N76.8 Other specified inflammation of vagina and vulva	0.003	0.997	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.000	0.997	0.003
S42.40 Fracture of lower end of humerus (closed)	0.003	0.997	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.003	0.997	0.000
Q22.1 Congenital pulmonary valve stenosis	0.003	0.997	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.003	0.997	0.000
H53.2 Diplopia	0.000	0.997	0.003
I05.8 Other mitral valve diseases	0.003	0.997	0.000
K63.9 Disease of intestine, unspecified	0.003	0.997	0.000
N89.8 Other specified noninflammatory disorders of vagina	0.003	0.997	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.003	0.997	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.003	0.997	0.000
Q22.6 Hypoplastic right heart syndrome	0.003	0.997	0.000
Q22.4 Congenital tricuspid stenosis	0.003	0.997	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.003	0.997	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.003	0.997	0.000
Q22.0 Pulmonary valve atresia	0.003	0.997	0.000
I08.8 Other multiple valve diseases	0.003	0.997	0.000
Q18.1 Preauricular sinus and cyst	0.003	0.997	0.000
R00.2 Palpitations	0.003	0.997	0.000
S50.9 Superficial injury of forearm, unspecified	0.003	0.997	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
Q18 Other congenital malformations of face and neck	0.003	0.997	0.000
H06.2 Dysthyroid exophthalmos	0.003	0.997	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.000	0.997	0.003
M05.20 Rheumatoid vasculitis (Multiple sites)	0.000	0.997	0.003
G95.9 Disease of spinal cord, unspecified	0.000	0.997	0.003
I25.0 Atherosclerotic cardiovascular disease, so described	0.003	0.997	0.000
I95.9 Hypotension, unspecified	0.003	0.997	0.000
L81.7 Pigmented purpuric dermatosis	0.000	0.997	0.003
L81.6 Other disorders of diminished melanin formation	0.000	0.997	0.003
L81.5 Leukoderma, not elsewhere classified	0.000	0.997	0.003
L81.3 Cafe au lait spots	0.000	0.997	0.003
L81.1 Chloasma	0.000	0.997	0.003
J30.1 Allergic rhinitis due to pollen	0.003	0.997	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.003	0.997	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.003	0.997	0.000
I25.4 Coronary artery aneurysm	0.003	0.997	0.000
D61.0 Constitutional aplastic anaemia	0.003	0.997	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.003	0.997	0.000
Q21.4 Aortopulmonary septal defect	0.001	0.997	0.002
Q21.2 Atrioventricular septal defect	0.001	0.997	0.002
I08.2 Disorders of both aortic and tricuspid valves	0.003	0.997	0.000
N76.5 Ulceration of vagina	0.003	0.997	0.000
Q39 Congenital malformations of oesophagus	0.003	0.997	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.003	0.997	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.003	0.997	0.000
Q21.3 Tetralogy of Fallot	0.001	0.997	0.002
I22 Subsequent myocardial infarction	0.003	0.997	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.001	0.997	0.002
Q21.8 Other congenital malformations of cardiac septa	0.001	0.997	0.002
Q25 Congenital malformations of great arteries	0.003	0.997	0.000
L81.0 Postinflammatory hyperpigmentation	0.000	0.997	0.003
Q43 Other congenital malformations of intestine	0.003	0.997	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.000	0.997	0.003
I63.9 Cerebral infarction, unspecified	0.003	0.997	0.000
K25.4 Chronic or unspecified with haemorrhage	0.003	0.997	0.000
Q44.4 Choledochal cyst	0.003	0.997	0.000
I07.1 Tricuspid insufficiency	0.003	0.997	0.000
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
Q14 Congenital malformations of posterior segment of eye	0.003	0.997	0.000
Q14.1 Congenital malformation of retina	0.003	0.997	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.003	0.997	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
Q20.6 Isomerism of atrial appendages	0.003	0.997	0.000
Q20.5 Discordant atrioventricular connexion	0.003	0.997	0.000
Q20.4 Double inlet ventricle	0.003	0.997	0.000
Q20.3 Discordant ventriculoarterial connexion	0.003	0.997	0.000
Q20.2 Double outlet left ventricle	0.003	0.997	0.000
Q20.1 Double outlet right ventricle	0.003	0.997	0.000
Q20.0 Common arterial trunk	0.003	0.997	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.003	0.997	0.000
Q26.8 Other congenital malformations of great veins	0.003	0.997	0.000
Q26.6 Portal vein-hepatic artery fistula	0.003	0.997	0.000
Q26.5 Anomalous portal venous connexion	0.003	0.997	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.003	0.997	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.003	0.997	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.003	0.997	0.000
Q26.1 Persistent left superior vena cava	0.003	0.997	0.000
Q26.0 Congenital stenosis of vena cava	0.003	0.997	0.000
Q85 Phakomatoses, not elsewhere classified	0.000	0.997	0.002
T91.9 Sequelae of unspecified injury of neck and trunk	0.003	0.997	0.000
Q45 Other congenital malformations of digestive system	0.003	0.997	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.003	0.997	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.003	0.997	0.000
Q44.7 Other congenital malformations of liver	0.003	0.997	0.000
I25.6 Silent myocardial ischaemia	0.003	0.997	0.000
N85.2 Hypertrophy of uterus	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations