TreeWAS – Variant ID: rs4800452

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.027	0.973	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.026	0.974	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.026	0.974	0.000
T45.0 Antiallergic and antiemetic drugs	0.026	0.974	0.000
T40.2 Other opioids	0.025	0.975	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.025	0.975	0.000
T40.6 Other and unspecified narcotics	0.025	0.975	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.024	0.976	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.024	0.976	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.023	0.977	0.000
T36 Poisoning by systemic antibiotics	0.022	0.978	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.022	0.978	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.021	0.979	0.000
T40.3 Methadone	0.021	0.979	0.000
T45.5 Anticoagulants	0.021	0.979	0.000
T45.4 Iron and its compounds	0.021	0.979	0.000
T40.1 Heroin	0.021	0.979	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.021	0.979	0.000
R22.2 Localised swelling, mass and lump, trunk	0.020	0.980	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.020	0.980	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.020	0.980	0.000
T46.1 Calcium-channel blockers	0.020	0.980	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.019	0.980	0.000
T40.8 Lysergide [LSD]	0.019	0.980	0.000
T40.7 Cannabis (derivatives)	0.019	0.980	0.000
T40.0 Opium	0.019	0.980	0.000
T36.0 Penicillins	0.019	0.981	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.019	0.981	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.019	0.981	0.000
T40.4 Other synthetic narcotics	0.019	0.981	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.019	0.981	0.000
T45.8 Other primarily systemic and haematological agents	0.019	0.981	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.019	0.981	0.000
T45.6 Fibrinolysis-affecting drugs	0.019	0.981	0.000
T45.3 Enzymes, not elsewhere classified	0.019	0.981	0.000
T45.2 Vitamins, not elsewhere classified	0.019	0.981	0.000
T40.5 Cocaine	0.018	0.981	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.019	0.981	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.018	0.982	0.000
T39.0 Salicylates	0.018	0.982	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.018	0.982	0.000
T42.2 Succinimides and oxazolidinediones	0.018	0.982	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.018	0.982	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.018	0.982	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.017	0.982	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.017	0.983	0.000
T46.7 Peripheral vasodilators	0.017	0.983	0.000
T42.4 Benzodiazepines	0.017	0.983	0.000
T42.0 Hydantoin derivatives	0.017	0.983	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.017	0.983	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.017	0.983	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.017	0.983	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.017	0.983	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.016	0.984	0.000
T42.3 Barbiturates	0.016	0.984	0.000
T36.3 Macrolides	0.016	0.984	0.000
T36.9 Systemic antibiotic, unspecified	0.016	0.984	0.000
T36.7 Antifungal antibiotics, systemically used	0.016	0.984	0.000
T36.6 Rifamycins	0.016	0.984	0.000
T36.5 Aminoglycosides	0.016	0.984	0.000
T36.2 Chloramphenicol group	0.016	0.984	0.000
T39.1 4-Aminophenol derivatives	0.016	0.984	0.000
T42.1 Iminostilbenes	0.016	0.984	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.016	0.984	0.000
T36.8 Other systemic antibiotics	0.016	0.984	0.000
T36.4 Tetracyclines	0.016	0.984	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.016	0.984	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.016	0.984	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.015	0.985	0.000
T39.4 Antirheumatics, not elsewhere classified	0.015	0.985	0.000
T39.2 Pyrazolone derivatives	0.015	0.985	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.015	0.985	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.015	0.985	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.015	0.985	0.000
T37.5 Antiviral drugs	0.015	0.985	0.000
T37.4 Anthelminthics	0.015	0.985	0.000
T37.3 Other antiprotozoal drugs	0.015	0.985	0.000
T37.1 Antimycobacterial drugs	0.015	0.985	0.000
T37.0 Sulphonamides	0.015	0.985	0.000
T49.9 Topical agent, unspecified	0.015	0.985	0.000
T49.8 Other topical agents	0.015	0.985	0.000
T49.7 Dental drugs, topically applied	0.015	0.985	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.015	0.985	0.000
T49.5 Ophthalmological drugs and preparations	0.015	0.985	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.015	0.985	0.000
T49.3 Emollients, demulcents and protectants	0.015	0.985	0.000
T49.2 Local astringents and local detergents	0.015	0.985	0.000
T49.1 Antipruritics	0.015	0.985	0.000
T41.2 Other and unspecified general anaesthetics	0.014	0.986	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.014	0.986	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.014	0.986	0.000
T41.5 Therapeutic gases	0.014	0.986	0.000
T41.4 Anaesthetic, unspecified	0.014	0.986	0.000
T41.3 Local anaesthetics	0.014	0.986	0.000
T41.1 Intravenous anaesthetics	0.014	0.986	0.000
T41.0 Inhaled anaesthetics	0.014	0.986	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.013	0.986	0.000
T38.5 Other oestrogens and progestogens	0.013	0.986	0.000
T50.4 Drugs affecting uric acid metabolism	0.013	0.987	0.000
T38.0 Glucocorticoids and synthetic analogues	0.013	0.987	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.013	0.987	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.013	0.987	0.000
T38.9 Other and unspecified hormone antagonists	0.013	0.987	0.000
T38.7 Androgens and anabolic congeners	0.013	0.987	0.000
T38.4 Oral contraceptives	0.013	0.987	0.000
T38.2 Antithyroid drugs	0.013	0.987	0.000
M06.9 Rheumatoid arthritis, unspecified	0.013	0.987	0.000
T47.0 Histamine H(2)-receptor antagonists	0.012	0.988	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.012	0.988	0.000
T47.6 Antidiarrhoeal drugs	0.012	0.988	0.000
T47.2 Stimulant laxatives	0.012	0.988	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.012	0.988	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.012	0.988	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.012	0.988	0.000
T47.7 Emetics	0.012	0.988	0.000
T47.5 Digestants	0.012	0.988	0.000
T47.4 Other laxatives	0.012	0.988	0.000
T47.3 Saline and osmotic laxatives	0.012	0.988	0.000
T50.7 Analeptics and opioid receptor antagonists	0.012	0.988	0.000
T50.5 Appetite depressants	0.012	0.988	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.012	0.988	0.000
T50.0 Mineralocorticoids and their antagonists	0.012	0.988	0.000
T43.2 Other and unspecified antidepressants	0.012	0.988	0.000
T50.8 Diagnostic agents	0.012	0.988	0.000
T38.1 Thyroid hormones and substitutes	0.012	0.988	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.011	0.989	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.011	0.989	0.000
T48.4 Expectorants	0.011	0.989	0.000
T48.3 Antitussives	0.011	0.989	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.011	0.989	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.011	0.989	0.000
T48.0 Oxytocic drugs	0.011	0.989	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.011	0.989	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.011	0.989	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.011	0.989	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.011	0.989	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.011	0.989	0.000
T44.0 Anticholinesterase agents	0.011	0.989	0.000
C90.0 Multiple myeloma	0.011	0.989	0.000
T48.5 Anti-common-cold drugs	0.011	0.989	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.011	0.989	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.011	0.989	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.011	0.989	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.010	0.989	0.000
T50.1 Loop [high-ceiling] diuretics	0.010	0.989	0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.011	0.989	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.011	0.989	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.010	0.990	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.010	0.990	0.000
R22.0 Localised swelling, mass and lump, head	0.010	0.990	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.010	0.990	0.000
T43.9 Psychotropic drug, unspecified	0.010	0.990	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.010	0.990	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.009	0.990	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.009	0.991	0.000
R22.1 Localised swelling, mass and lump, neck	0.009	0.991	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.009	0.991	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.009	0.991	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.009	0.991	0.000
T43.6 Psychostimulants with abuse potential	0.009	0.991	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.008	0.991	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.008	0.992	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.007	0.992	0.001
R22.9 Localised swelling, mass and lump, unspecified	0.008	0.992	0.000
H73.8 Other specified disorders of tympanic membrane	0.008	0.992	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.008	0.992	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.008	0.992	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.008	0.992	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.008	0.992	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.007	0.992	0.000
H65.2 Chronic serous otitis media	0.007	0.993	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.007	0.993	0.000
C90.2 Plasmacytoma, extramedullary	0.007	0.993	0.000
H73 Other disorders of tympanic membrane	0.007	0.993	0.000
R22.7 Localised swelling, mass and lump, multiple sites	0.007	0.993	0.000
H74 Other disorders of middle ear and mastoid	0.007	0.993	0.000
H65-H75 Diseases of middle ear and mastoid	0.007	0.993	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.007	0.993	0.000
J02.9 Acute pharyngitis, unspecified	0.007	0.993	0.000
H65 Nonsuppurative otitis media	0.007	0.993	0.000
H72 Perforation of tympanic membrane	0.007	0.993	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.007	0.993	0.000
H72.2 Other marginal perforations of tympanic membrane	0.007	0.993	0.000
H72.0 Central perforation of tympanic membrane	0.006	0.994	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.994	0.006
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.994	0.006
H65.4 Other chronic nonsuppurative otitis media	0.006	0.994	0.000
H72.1 Attic perforation of tympanic membrane	0.006	0.994	0.000
C90.3 Solitary plasmacytoma	0.006	0.994	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.006	0.994	0.000
H69 Other disorders of Eustachian tube	0.006	0.994	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.006	0.994	0.000
O14.1 Severe preeclampsia	0.000	0.994	0.006
N82.3 Fistula of vagina to large intestine	0.000	0.994	0.006
H54.9 Unspecified visual impairment (binocular)	0.006	0.994	0.000
H73.1 Chronic myringitis	0.006	0.994	0.000
M67.8 Other specified disorders of synovium and tendon	0.006	0.994	0.000
M07.3 Other psoriatic arthropathies	0.000	0.995	0.005
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.995	0.005
H74.1 Adhesive middle ear disease	0.005	0.995	0.000
O14.9 Preeclampsia, unspecified	0.000	0.995	0.005
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.005	0.995	0.000
H67 Otitis media in diseases classified elsewhere	0.005	0.995	0.000
H73.0 Acute myringitis	0.005	0.995	0.000
H69.9 Eustachian tube disorder, unspecified	0.005	0.995	0.000
H65.3 Chronic mucoid otitis media	0.005	0.995	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.005	0.995	0.000
H71 Cholesteatoma of middle ear	0.005	0.995	0.000
H68 Eustachian salpingitis and obstruction	0.005	0.995	0.000
C90.1 Plasma cell leukaemia	0.005	0.995	0.000
S32.0 Fracture of lumbar vertebra	0.005	0.995	0.000
H65.1 Other acute nonsuppurative otitis media	0.005	0.995	0.000
M06 Other rheumatoid arthritis	0.005	0.995	0.000
R22.3 Localised swelling, mass and lump, upper limb	0.005	0.995	0.000
H65.0 Acute serous otitis media	0.005	0.995	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.005	0.995	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.995	0.005
O14.0 Moderate preeclampsia	0.000	0.995	0.005
H66 Suppurative and unspecified otitis media	0.005	0.995	0.000
M07.38 Other psoriatic arthropathies (Other)	0.000	0.995	0.005
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.995	0.005
N82 Fistulae involving female genital tract	0.000	0.995	0.005
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.995	0.004
H74.0 Tympanosclerosis	0.004	0.995	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.004	0.995	0.000
H69.0 Patulous Eustachian tube	0.004	0.995	0.000
H69.8 Other specified disorders of Eustachian tube	0.004	0.996	0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.004	0.996	0.000
H70 Mastoiditis and related conditions	0.004	0.996	0.000
H74.4 Polyp of middle ear	0.004	0.996	0.000
C02.1 Border of tongue	0.000	0.996	0.004
T20-T25 Burns and corrosions of external body surface, specified by site	0.000	0.996	0.004
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.000	0.996	0.004
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.000	0.996	0.004
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.996	0.004
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.996	0.004
O14.2 HELLP syndrome	0.000	0.996	0.004
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.996	0.004
N82.1 Other female urinary-genital tract fistulae	0.000	0.996	0.004
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.996	0.004
H66.9 Otitis media, unspecified	0.004	0.996	0.000
N82.0 Vesicovaginal fistula	0.000	0.996	0.004
H67.8 Otitis media in other diseases classified elsewhere	0.004	0.996	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.004	0.996	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.004	0.996	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.004	0.996	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.996	0.004
N82.4 Other female intestinal-genital tract fistulae	0.000	0.996	0.004
O12.1 Gestational proteinuria	0.000	0.996	0.004
M06.8 Other specified rheumatoid arthritis	0.004	0.996	0.000
T23 Burn and corrosion of wrist and hand	0.000	0.996	0.004
M23.8 Other internal derangements of knee	0.000	0.996	0.004
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.996	0.004
N82.8 Other female genital tract fistulae	0.000	0.996	0.004
T25 Burn and corrosion of ankle and foot	0.000	0.996	0.004
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.996	0.004
T23.0 Burn of unspecified degree of wrist and hand	0.000	0.996	0.004
H66.4 Suppurative otitis media, unspecified	0.004	0.996	0.000
T25.3 Burn of third degree of ankle and foot	0.000	0.996	0.004
M06.0 Seronegative rheumatoid arthritis	0.004	0.996	0.000
T21 Burn and corrosion of trunk	0.000	0.996	0.004
H68.0 Eustachian salpingitis	0.004	0.996	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.000	0.996	0.004
S32.01 Fracture of lumbar vertebra (open)	0.004	0.996	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.004	0.996	0.000
K61.0 Anal abscess	0.004	0.996	0.000
M06.2 Rheumatoid bursitis	0.004	0.996	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.004	0.996	0.000
J02 Acute pharyngitis	0.004	0.996	0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.004	0.996	0.000
N82.5 Female genital tract-skin fistulae	0.000	0.996	0.004
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.000	0.996	0.004
R23 Other skin changes	0.004	0.996	0.000
N83.1 Corpus luteum cyst	0.004	0.996	0.000
M06.1 Adult-onset Still's disease	0.003	0.996	0.000
N82.2 Fistula of vagina to small intestine	0.000	0.996	0.003
N82.9 Female genital tract fistula, unspecified	0.000	0.996	0.003
M06.4 Inflammatory polyarthropathy	0.003	0.996	0.000
T21.2 Burn of second degree of trunk	0.000	0.996	0.003
R23.0 Cyanosis	0.003	0.996	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.004	0.996	0.000
H66.0 Acute suppurative otitis media	0.003	0.996	0.000
C78.2 Secondary malignant neoplasm of pleura	0.004	0.996	0.000
H70.9 Mastoiditis, unspecified	0.003	0.996	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.000	0.996	0.003
O16 Unspecified maternal hypertension	0.000	0.996	0.004
H68.1 Obstruction of Eustachian tube	0.003	0.997	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.997	0.003
T20 Burn and corrosion of head and neck	0.000	0.997	0.003
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.003	0.997	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.003	0.997	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.003	0.997	0.000
H70.2 Petrositis	0.003	0.997	0.000
J02.8 Acute pharyngitis due to other specified organisms	0.003	0.997	0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.000	0.997	0.003
M06.04 Seronegative rheumatoid arthritis (Hand)	0.003	0.997	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.000	0.997	0.003
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.997	0.003
M23.80 Other internal derangements of knee (Multiple sites)	0.000	0.997	0.003
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.997	0.003
M70.6 Trochanteric bursitis	0.003	0.997	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.000	0.997	0.003
G44.2 Tension-type headache	0.000	0.997	0.003
J32.2 Chronic ethmoidal sinusitis	0.003	0.997	0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.000	0.997	0.003
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.000	0.997	0.003
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.000	0.997	0.003
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.000	0.997	0.003
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.000	0.997	0.003
H72.9 Perforation of tympanic membrane, unspecified	0.003	0.997	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.000	0.997	0.003
M67 Other disorders of synovium and tendon	0.003	0.997	0.000
T21.1 Burn of first degree of trunk	0.000	0.997	0.003
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.000	0.997	0.003
M70.46 Prepatellar bursitis-Lower Leg	0.003	0.997	0.000
H70.8 Other mastoiditis and related conditions	0.003	0.997	0.000
N60.4 Mammary duct ectasia	0.003	0.997	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.003	0.997	0.000
M07 Psoriatic and enteropathic arthropathies	0.001	0.997	0.003
T25.2 Burn of second degree of ankle and foot	0.000	0.997	0.003
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.003
H72.8 Other perforations of tympanic membrane	0.003	0.997	0.000
T23.1 Burn of first degree of wrist and hand	0.000	0.997	0.003
M06.88 Other specified rheumatoid arthritis (Other)	0.003	0.997	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.003	0.997	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.003	0.997	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.003	0.997	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.003	0.997	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.003	0.997	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.003	0.997	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.003	0.997	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.003	0.997	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.000	0.997	0.003
S32.40 Fracture of acetabulum (closed)	0.003	0.997	0.000
T23.7 Corrosion of third degree of wrist and hand	0.000	0.997	0.003
T23.6 Corrosion of second degree of wrist and hand	0.000	0.997	0.003
T23.5 Corrosion of first degree of wrist and hand	0.000	0.997	0.003
T23.4 Corrosion of unspecified degree of wrist and hand	0.000	0.997	0.003
T23.2 Burn of second degree of wrist and hand	0.000	0.997	0.003
R23.2 Flushing	0.003	0.997	0.000
T25.7 Corrosion of third degree of ankle and foot	0.000	0.997	0.003
T25.6 Corrosion of second degree of ankle and foot	0.000	0.997	0.003
T25.5 Corrosion of first degree of ankle and foot	0.000	0.997	0.003
T25.4 Corrosion of unspecified degree of ankle and foot	0.000	0.997	0.003
T25.1 Burn of first degree of ankle and foot	0.000	0.997	0.003
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.997	0.003
H70.0 Acute mastoiditis	0.003	0.997	0.000
R23.8 Other and unspecified skin changes	0.003	0.997	0.000
T23.3 Burn of third degree of wrist and hand	0.000	0.997	0.003
T21.0 Burn of unspecified degree of trunk	0.000	0.997	0.003
M06.08 Seronegative rheumatoid arthritis (Other)	0.003	0.997	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.003	0.997	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.003	0.997	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.003	0.997	0.000
T21.7 Corrosion of third degree of trunk	0.000	0.997	0.003
T21.6 Corrosion of second degree of trunk	0.000	0.997	0.003
T21.5 Corrosion of first degree of trunk	0.000	0.997	0.003
T21.4 Corrosion of unspecified degree of trunk	0.000	0.997	0.003
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.003	0.997	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.000	0.997	0.003
C02 Malignant neoplasm of other and unspecified parts of tongue	0.000	0.997	0.003
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.003	0.997	0.000
C81.9 Hodgkin's disease, unspecified	0.003	0.997	0.000
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.000	0.997	0.003
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.000	0.997	0.003
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.000	0.997	0.003
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.000	0.997	0.003
M79.89 Other specified soft tissue disorders (Site unspecified)	0.000	0.997	0.003
T25.0 Burn of unspecified degree of ankle and foot	0.000	0.997	0.003
S42.10 Fracture of scapula (closed)	0.000	0.997	0.003
T20.1 Burn of first degree of head and neck	0.000	0.997	0.003
S32.4 Fracture of acetabulum	0.003	0.997	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.003	0.997	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.003	0.997	0.000
M06.28 Rheumatoid bursitis (Other)	0.003	0.997	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.003	0.997	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.003	0.997	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.003	0.997	0.000
M06.24 Rheumatoid bursitis (Hand)	0.003	0.997	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.003	0.997	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.003	0.997	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.003	0.997	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.003	0.997	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.003	0.997	0.000
T20.3 Burn of third degree of head and neck	0.000	0.997	0.003
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.003	0.997	0.000
T21.3 Burn of third degree of trunk	0.000	0.997	0.003
H54.0 Blindness, both eyes	0.003	0.997	0.000
S32 Fracture of lumbar spine and pelvis	0.003	0.997	0.000
M06.18 Adult-onset Still's disease (Other)	0.003	0.997	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.003	0.997	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.003	0.997	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.003	0.997	0.000
M06.14 Adult-onset Still's disease (Hand)	0.003	0.997	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.003	0.997	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.003	0.997	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.003	0.997	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.003	0.997	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.997	0.003
M67.0 Short Achilles tendon (acquired)	0.003	0.997	0.000
M70.4 Prepatellar bursitis	0.003	0.997	0.000
C02.9 Tongue, unspecified	0.000	0.997	0.003
M06.48 Inflammatory polyarthropathy (Other)	0.003	0.997	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.003	0.997	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.003	0.997	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.003	0.997	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.003	0.997	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.003	0.997	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.003	0.997	0.000
C81 Hodgkin's disease	0.003	0.997	0.000
W45 Foreign body or object entering through skin	0.003	0.997	0.000
J02.0 Streptococcal pharyngitis	0.003	0.997	0.000
R23.4 Changes in skin texture	0.003	0.997	0.000
C73 Malignant neoplasm of thyroid gland	0.000	0.997	0.003
O12.2 Gestational oedema with proteinuria	0.000	0.997	0.003
W45.6 Industrial and construction area	0.003	0.997	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.997	0.003
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.997	0.003
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.997	0.003
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.997	0.003
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.997	0.003
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.997	0.003
T20.7 Corrosion of third degree of head and neck	0.000	0.997	0.003
T20.6 Corrosion of second degree of head and neck	0.000	0.997	0.003
T20.5 Corrosion of first degree of head and neck	0.000	0.997	0.003
T20.4 Corrosion of unspecified degree of head and neck	0.000	0.997	0.003
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites	0.003	0.997	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.997	0.003
C02.4 Lingual tonsil	0.000	0.997	0.003
R23.3 Spontaneous ecchymoses	0.003	0.997	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.002	0.997	0.000
H70.1 Chronic mastoiditis	0.002	0.997	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.003	0.997	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.003	0.997	0.000
C85.1 B-cell lymphoma, unspecified	0.003	0.997	0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.000	0.997	0.003
F03 Unspecified dementia	0.000	0.997	0.003
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.003	0.997	0.000
M07.6 Other enteropathic arthropathies	0.001	0.997	0.002
R23.1 Pallor	0.003	0.997	0.000
M70.68 Trochanteric bursitis-Other	0.003	0.997	0.000
M70.67 Trochanteric bursitis-Ankle/Foot	0.003	0.997	0.000
M70.66 Trochanteric bursitis-Lower Leg	0.003	0.997	0.000
M70.64 Trochanteric bursitis-Hand	0.003	0.997	0.000
M70.63 Trochanteric bursitis-Forearm	0.003	0.997	0.000
M70.62 Trochanteric bursitis-Upper arm	0.003	0.997	0.000
M70.61 Trochanteric bursitis-Shldr region	0.003	0.997	0.000
M70.60 Trochanteric bursitis-Mult sites	0.003	0.997	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.003	0.997	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.997	0.003
W45.8 Other specified place	0.003	0.997	0.000
H54 Blindness and low vision	0.003	0.997	0.000
T14.0 Superficial injury of unspecified body region	0.003	0.997	0.000
M70.69 Trochanteric bursitis-Site unspec	0.002	0.997	0.000
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec	0.003	0.997	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.000	0.997	0.003
M67.9 Disorder of synovium and tendon, unspecified	0.002	0.997	0.000
M67.3 Transient synovitis	0.002	0.997	0.000
R20 Disturbances of skin sensation	0.003	0.997	0.000
C81.0 Lymphocytic predominance	0.003	0.997	0.000
M07.5 Arthropathy in ulcerative colitis	0.001	0.997	0.002
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.001	0.997	0.002
M07.2 Psoriatic spondylitis	0.001	0.997	0.002
M07.1 Arthritis mutilans	0.001	0.997	0.002
M07.0 Distal interphalangeal psoriatic arthropathy	0.001	0.997	0.002
M67.1 Other contracture of tendon (sheath)	0.003	0.997	0.000
S00.8 Superficial injury of other parts of head	0.003	0.997	0.000
T20.0 Burn of unspecified degree of head and neck	0.000	0.997	0.002
M70 Soft tissue disorders related to use, overuse and pressure	0.003	0.997	0.000
O15 Eclampsia	0.000	0.997	0.002
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.000	0.997	0.002
W45.5 Trade and service area	0.002	0.997	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.002
M79.79 Fibromyalgia (Site unspecified)	0.000	0.997	0.002
C02.8 Overlapping lesion of tongue	0.000	0.997	0.002
M67.4 Ganglion	0.002	0.997	0.000
C02.0 Dorsal surface of tongue	0.000	0.998	0.002
C02.2 Ventral surface of tongue	0.000	0.998	0.002
C81.2 Mixed cellularity	0.002	0.998	0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.000	0.998	0.002
O12.0 Gestational oedema	0.000	0.998	0.002
T20.2 Burn of second degree of head and neck	0.000	0.998	0.002
M06.46 Inflammatory polyarthropathy (Lower leg)	0.002	0.998	0.000
S32.41 Fracture of acetabulum (open)	0.002	0.998	0.000
M06.3 Rheumatoid nodule	0.002	0.998	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.002	0.998	0.000
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other	0.002	0.998	0.000
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg	0.002	0.998	0.000
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh	0.002	0.998	0.000
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm	0.002	0.998	0.000
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm	0.002	0.998	0.000
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region	0.002	0.998	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
C88 Malignant immunoproliferative diseases	0.002	0.998	0.000
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot	0.002	0.998	0.000
S32.2 Fracture of coccyx	0.002	0.998	0.000
W25.9 Unspecified place	0.002	0.998	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations