TreeWAS – Variant ID: rs4809324

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M25.57 Pain in joint (Ankle and foot)	0.351	0.649	0.000
M25.5 Pain in joint	0.350	0.650	0.000
M25.56 Pain in joint (Lower leg)	0.348	0.652	0.000
M25.54 Pain in joint (Hand)	0.310	0.690	0.000
M25 Other joint disorders, not elsewhere classified	0.303	0.697	0.000
M25.50 Pain in joint (Multiple sites)	0.288	0.712	0.000
M25.3 Other instability of joint	0.275	0.725	0.000
M25.52 Pain in joint (Upper arm)	0.262	0.738	0.000
M25.58 Pain in joint (Other)	0.252	0.748	0.000
M25.0 Haemarthrosis	0.252	0.748	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.248	0.751	0.000
M25.8 Other specified joint disorders	0.245	0.755	0.000
M25.31 Other instability of joint (Shoulder region)	0.241	0.759	0.000
M25.9 Joint disorder, unspecified	0.240	0.760	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.225	0.775	0.000
M25.86 Other specified joint disorders (Lower leg)	0.225	0.775	0.000
M25.59 Pain in joint (Site unspecified)	0.224	0.775	0.000
M25.2 Flail joint	0.218	0.782	0.000
M25.1 Fistula of joint	0.218	0.782	0.000
M25.06 Haemarthrosis (Lower leg)	0.215	0.785	0.000
M25.34 Other instability of joint (Hand)	0.214	0.786	0.000
M25.37 Other instability of joint (Ankle and foot)	0.210	0.790	0.000
M25.33 Other instability of joint (Forearm)	0.203	0.797	0.000
M25.51 Pain in joint (Shoulder region)	0.200	0.800	0.000
M25.36 Other instability of joint (Lower leg)	0.198	0.802	0.000
M25.39 Other instability of joint (Site unspecified)	0.197	0.803	0.000
M25.38 Other instability of joint (Other)	0.197	0.803	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.197	0.803	0.000
M25.32 Other instability of joint (Upper arm)	0.197	0.803	0.000
M25.30 Other instability of joint (Multiple sites)	0.197	0.803	0.000
M25.94 Joint disorder, unspecified (Hand)	0.195	0.805	0.000
M25.4 Effusion of joint	0.195	0.805	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.194	0.806	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.187	0.812	0.000
M25.53 Pain in joint (Forearm)	0.186	0.814	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.185	0.815	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.184	0.816	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.181	0.819	0.000
M25.09 Haemarthrosis (Site unspecified)	0.181	0.819	0.000
M25.08 Haemarthrosis (Other)	0.181	0.819	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.181	0.819	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.181	0.819	0.000
M25.04 Haemarthrosis (Hand)	0.181	0.819	0.000
M25.03 Haemarthrosis (Forearm)	0.181	0.819	0.000
M25.02 Haemarthrosis (Upper arm)	0.181	0.819	0.000
M25.01 Haemarthrosis (Shoulder region)	0.181	0.819	0.000
M25.00 Haemarthrosis (Multiple sites)	0.181	0.819	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.178	0.822	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.178	0.822	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.178	0.822	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.178	0.822	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.178	0.822	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.176	0.824	0.000
M25.88 Other specified joint disorders (Other)	0.176	0.824	0.000
M25.82 Other specified joint disorders (Upper arm)	0.176	0.824	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.176	0.824	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.175	0.825	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.174	0.826	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.172	0.827	0.000
M25.98 Joint disorder, unspecified (Other)	0.172	0.827	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.172	0.827	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.172	0.827	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.172	0.827	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.172	0.827	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.172	0.827	0.000
M25.83 Other specified joint disorders (Forearm)	0.165	0.835	0.000
M25.19 Fistula of joint (Site unspecified)	0.156	0.844	0.000
M25.18 Fistula of joint (Other)	0.156	0.844	0.000
M25.17 Fistula of joint (Ankle and foot)	0.156	0.844	0.000
M25.16 Fistula of joint (Lower leg)	0.156	0.844	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.156	0.844	0.000
M25.14 Fistula of joint (Hand)	0.156	0.844	0.000
M25.13 Fistula of joint (Forearm)	0.156	0.844	0.000
M25.12 Fistula of joint (Upper arm)	0.156	0.844	0.000
M25.11 Fistula of joint (Shoulder region)	0.156	0.844	0.000
M25.10 Fistula of joint (Multiple sites)	0.156	0.844	0.000
M25.29 Flail joint (Site unspecified)	0.156	0.844	0.000
M25.28 Flail joint (Other)	0.156	0.844	0.000
M25.27 Flail joint (Ankle and foot)	0.156	0.844	0.000
M25.26 Flail joint (Lower leg)	0.156	0.844	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.156	0.844	0.000
M25.24 Flail joint (Hand)	0.156	0.844	0.000
M25.23 Flail joint (Forearm)	0.156	0.844	0.000
M25.22 Flail joint (Upper arm)	0.156	0.844	0.000
M25.21 Flail joint (Shoulder region)	0.156	0.844	0.000
M25.20 Flail joint (Multiple sites)	0.156	0.844	0.000
M25.7 Osteophyte	0.153	0.847	0.000
M25.84 Other specified joint disorders (Hand)	0.153	0.847	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.147	0.853	0.000
M25.44 Effusion of joint (Hand)	0.147	0.853	0.000
M25.46 Effusion of joint (Lower leg)	0.145	0.855	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.141	0.859	0.000
M25.43 Effusion of joint (Forearm)	0.140	0.859	0.000
M25.49 Effusion of joint (Site unspecified)	0.140	0.860	0.000
M25.48 Effusion of joint (Other)	0.140	0.860	0.000
M25.42 Effusion of joint (Upper arm)	0.140	0.860	0.000
M25.41 Effusion of joint (Shoulder region)	0.140	0.860	0.000
M25.40 Effusion of joint (Multiple sites)	0.140	0.860	0.000
M25.77 Osteophyte (Ankle and foot)	0.138	0.861	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.864	0.136
M25.73 Osteophyte (Forearm)	0.133	0.867	0.000
J44 Other chronic obstructive pulmonary disease	0.000	0.871	0.129
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.871	0.129
M25.45 Effusion of joint (Pelvic region and thigh)	0.126	0.874	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.119	0.881	0.000
M25.72 Osteophyte (Upper arm)	0.117	0.883	0.000
M25.47 Effusion of joint (Ankle and foot)	0.116	0.884	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.890	0.110
M25.79 Osteophyte (Site unspecified)	0.110	0.890	0.000
M25.70 Osteophyte (Multiple sites)	0.110	0.890	0.000
M25.78 Osteophyte (Other)	0.101	0.899	0.000
M25.71 Osteophyte (Shoulder region)	0.085	0.914	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.918	0.082
M25.74 Osteophyte (Hand)	0.078	0.921	0.000
M20-M25 Other joint disorders	0.067	0.933	0.000
M24 Other specific joint derangements	0.063	0.937	0.000
C67.9 Bladder, unspecified	0.059	0.941	0.000
M34 Systemic sclerosis	0.058	0.942	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.057	0.943	0.000
M35 Other systemic involvement of connective tissue	0.057	0.943	0.000
M24.5 Contracture of joint	0.057	0.943	0.000
M25.76 Osteophyte (Lower leg)	0.056	0.944	0.000
C67 Malignant neoplasm of bladder	0.054	0.946	0.000
M24.6 Ankylosis of joint	0.052	0.948	0.000
M24.0 Loose body in joint	0.050	0.950	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.050	0.950	0.000
M34.1 CR(E)ST syndrome	0.049	0.951	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.049	0.951	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.048	0.952	0.000
M24.54 Contracture of joint (Hand)	0.048	0.952	0.000
M24.51 Contracture of joint (Shoulder region)	0.048	0.952	0.000
C67.0 Trigone of bladder	0.048	0.952	0.000
M35.0 Sicca syndrome [Sjogren]	0.047	0.952	0.000
M35.7 Hypermobility syndrome	0.047	0.953	0.000
M33 Dermatopolymyositis	0.047	0.953	0.000
M30 Polyarteritis nodosa and related conditions	0.046	0.954	0.000
M32 Systemic lupus erythematosus	0.046	0.954	0.000
C67.4 Posterior wall of bladder	0.046	0.954	0.000
C64-C68 Malignant neoplasms of urinary tract	0.046	0.954	0.000
M24.9 Joint derangement, unspecified	0.046	0.954	0.000
M24.7 Protrusio acetabuli	0.046	0.954	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.046	0.954	0.000
M35.1 Other overlap syndromes	0.045	0.955	0.000
M34.9 Systemic sclerosis, unspecified	0.045	0.955	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.045	0.955	0.000
M31 Other necrotising vasculopathies	0.045	0.955	0.000
M34.8 Other forms of systemic sclerosis	0.044	0.956	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.044	0.956	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.043	0.956	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.043	0.956	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.043	0.957	0.000
C67.6 Ureteric orifice	0.043	0.957	0.000
M35.2 Behcet's disease	0.042	0.957	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.042	0.958	0.000
M34.0 Progressive systemic sclerosis	0.042	0.958	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.042	0.958	0.000
C67.8 Overlapping lesion of bladder	0.042	0.958	0.000
C67.1 Dome of bladder	0.041	0.959	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.041	0.959	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.041	0.959	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.041	0.959	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.041	0.959	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.041	0.959	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.041	0.959	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.041	0.959	0.000
M35.8 Other specified systemic involvement of connective tissue	0.041	0.959	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.041	0.959	0.000
M35.5 Multifocal fibrosclerosis	0.041	0.959	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.041	0.959	0.000
M24.59 Contracture of joint (Site unspecified)	0.041	0.959	0.000
M24.58 Contracture of joint (Other)	0.041	0.959	0.000
M24.57 Contracture of joint (Ankle and foot)	0.041	0.959	0.000
M24.56 Contracture of joint (Lower leg)	0.041	0.959	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.041	0.959	0.000
M24.53 Contracture of joint (Forearm)	0.041	0.959	0.000
M24.52 Contracture of joint (Upper arm)	0.041	0.959	0.000
M24.50 Contracture of joint (Multiple sites)	0.041	0.959	0.000
M24.07 Loose body in joint (Ankle and foot)	0.041	0.959	0.000
C67.7 Urachus	0.039	0.961	0.000
M24.1 Other articular cartilage disorders	0.038	0.962	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.038	0.962	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.037	0.963	0.000
M24.68 Ankylosis of joint (Other)	0.037	0.963	0.000
M24.66 Ankylosis of joint (Lower leg)	0.037	0.963	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.037	0.963	0.000
M24.64 Ankylosis of joint (Hand)	0.037	0.963	0.000
M24.63 Ankylosis of joint (Forearm)	0.037	0.963	0.000
M24.62 Ankylosis of joint (Upper arm)	0.037	0.963	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.037	0.963	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.037	0.963	0.000
M22 Disorders of patella	0.037	0.963	0.000
M24.01 Loose body in joint (Shoulder region)	0.037	0.963	0.000
M24.2 Disorder of ligament	0.036	0.963	0.000
M31.7 Microscopic polyangiitis	0.036	0.963	0.000
C67.5 Bladder neck	0.036	0.964	0.000
M24.09 Loose body in joint (Site unspecified)	0.036	0.964	0.000
M24.08 Loose body in joint (Other)	0.036	0.964	0.000
M24.06 Loose body in joint-Lower leg	0.036	0.964	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.036	0.964	0.000
M24.04 Loose body in joint (Hand)	0.036	0.964	0.000
M24.03 Loose body in joint (Forearm)	0.036	0.964	0.000
M24.00 Loose body in joint (Multiple sites)	0.036	0.964	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.035	0.965	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.035	0.965	0.000
M36.3 Arthropathy in other blood disorders	0.035	0.965	0.000
M36.2 Haemophilic arthropathy	0.035	0.965	0.000
M36.1 Arthropathy in neoplastic disease	0.035	0.965	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.035	0.965	0.000
M24.02 Loose body in joint (Upper arm)	0.035	0.965	0.000
M33.9 Dermatopolymyositis, unspecified	0.034	0.966	0.000
M33.0 Juvenile dermatomyositis	0.034	0.966	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.033	0.966	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.033	0.966	0.000
M30.2 Juvenile polyarteritis	0.033	0.966	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.033	0.967	0.000
M32.8 Other forms of systemic lupus erythematosus	0.033	0.967	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.033	0.967	0.000
C61 Malignant neoplasm of prostate	0.033	0.967	0.000
C67.3 Anterior wall of bladder	0.033	0.967	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.033	0.967	0.000
M33.2 Polymyositis	0.033	0.967	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.033	0.967	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.033	0.967	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.033	0.967	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.033	0.967	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.033	0.967	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.033	0.967	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.033	0.967	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.033	0.967	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.033	0.967	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.033	0.967	0.000
M24.79 Protrusio acetabuli-Site unspec	0.033	0.967	0.000
M24.78 Protrusio acetabuli-Other	0.033	0.967	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.033	0.967	0.000
M24.76 Protrusio acetabuli-Lower leg	0.033	0.967	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.033	0.967	0.000
M24.74 Protrusio acetabuli-Hand	0.033	0.967	0.000
M24.73 Protrusio acetabuli-Forearm	0.033	0.967	0.000
M24.72 Protrusio acetabuli-Upper arm	0.033	0.967	0.000
M24.71 Protrusio acetabuli-Shldr region	0.033	0.967	0.000
M24.70 Protrusio acetabuli-Mult sites	0.033	0.967	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.033	0.967	0.000
M24.98 Joint derangement, unspecified (Other)	0.033	0.967	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.033	0.967	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.033	0.967	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.033	0.967	0.000
M24.94 Joint derangement, unspecified (Hand)	0.033	0.967	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.033	0.967	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.033	0.967	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.033	0.967	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.033	0.967	0.000
M33.1 Other dermatomyositis	0.033	0.967	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.033	0.967	0.000
C68.0 Urethra	0.033	0.967	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.033	0.967	0.000
M31.9 Necrotising vasculopathy, unspecified	0.032	0.968	0.000
M31.8 Other specified necrotising vasculopathies	0.032	0.968	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.032	0.968	0.000
M31.2 Lethal midline granuloma	0.032	0.968	0.000
M31.1 Thrombotic microangiopathy	0.032	0.968	0.000
M31.0 Hypersensitivity angiitis	0.032	0.968	0.000
M30.0 Polyarteritis nodosa	0.032	0.968	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.031	0.969	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.031	0.969	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.031	0.969	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.031	0.969	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.031	0.969	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.031	0.969	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.031	0.969	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.031	0.969	0.000
M31.6 Other giant cell arteritis	0.031	0.969	0.000
M31.3 Wegener's granulomatosis	0.031	0.969	0.000
C66 Malignant neoplasm of ureter	0.030	0.970	0.000
M22.3 Other derangements of patella	0.030	0.970	0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.029	0.970	0.000
M22.0 Recurrent dislocation of patella	0.029	0.971	0.000
M24.24 Disorder of ligament (Hand)	0.028	0.971	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.028	0.972	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.028	0.972	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.028	0.972	0.000
M24.18 Other articular cartilage disorders (Other)	0.028	0.972	0.000
M24.14 Other articular cartilage disorders (Hand)	0.028	0.972	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.028	0.972	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.028	0.972	0.000
C68.9 Urinary organ, unspecified	0.027	0.972	0.000
C68.8 Overlapping lesion of urinary organs	0.027	0.972	0.000
C68.1 Paraurethral glands	0.027	0.972	0.000
M35.3 Polymyalgia rheumatica	0.027	0.973	0.000
M24.21 Disorder of ligament (Shoulder region)	0.027	0.973	0.000
C65 Malignant neoplasm of renal pelvis	0.027	0.973	0.000
C60-C63 Malignant neoplasms of male genital organs	0.027	0.973	0.000
M22.1 Recurrent subluxation of patella	0.027	0.973	0.000
M22.9 Disorder of patella, unspecified	0.027	0.973	0.000
M22.2 Patellofemoral disorders	0.027	0.973	0.000
M24.29 Disorder of ligament (Site unspecified)	0.026	0.973	0.000
M24.28 Disorder of ligament (Other)	0.026	0.973	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.026	0.973	0.000
M24.22 Disorder of ligament (Upper arm)	0.026	0.973	0.000
M24.20 Disorder of ligament (Multiple sites)	0.026	0.973	0.000
C67.2 Lateral wall of bladder	0.026	0.974	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.026	0.974	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.026	0.974	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.026	0.974	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.025	0.975	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.025	0.975	0.000
M24.23 Disorder of ligament (Forearm)	0.024	0.975	0.000
M24.26 Disorder of ligament (Lower leg)	0.024	0.976	0.000
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.024	0.976	0.000
M23 Internal derangement of knee	0.024	0.976	0.000
M23.5 Chronic instability of knee	0.023	0.977	0.000
Chapter II Neoplasms	0.021	0.979	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.021	0.979	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.021	0.979	0.000
C71 Malignant neoplasm of brain	0.021	0.979	0.000
C60 Malignant neoplasm of penis	0.020	0.980	0.000
C62 Malignant neoplasm of testis	0.020	0.980	0.000
C63 Malignant neoplasm of other and unspecified male genital organs	0.019	0.980	0.000
M22.10 Recurrent subluxation of patella, unspecified knee	0.019	0.980	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.019	0.981	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.018	0.981	0.000
C71.4 Occipital lobe	0.018	0.981	0.000
C71.0 Cerebrum, except lobes and ventricles	0.018	0.982	0.000
M23.0 Cystic meniscus	0.018	0.982	0.000
M23.9 Internal derangement of knee, unspecified	0.018	0.982	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.018	0.982	0.000
M22.4 Chondromalacia patellae	0.018	0.982	0.000
M21 Other acquired deformities of limbs	0.017	0.982	0.000
M22.8 Other disorders of patella	0.017	0.983	0.000
I25.1 Atherosclerotic heart disease	0.000	0.983	0.017
D37-D48 Neoplasms of uncertain or unknown behaviour	0.017	0.983	0.000
D45 Polycythaemia vera	0.017	0.983	0.000
M23.4 Loose body in knee	0.017	0.983	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.017	0.983	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.017	0.983	0.000
C71.3 Parietal lobe	0.017	0.983	0.000
C45 Mesothelioma	0.017	0.983	0.000
C69 Malignant neoplasm of eye and adnexa	0.017	0.983	0.000
M23.57 Chronic instability of knee (Capsular ligament)	0.016	0.983	0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.016	0.983	0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.016	0.983	0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.016	0.983	0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.016	0.983	0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.016	0.983	0.000
M23.50 Chronic instability of knee (Multiple sites)	0.016	0.983	0.000
M23.1 Discoid meniscus (congenital)	0.016	0.984	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.016	0.984	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.016	0.984	0.000
C71.1 Frontal lobe	0.016	0.984	0.000
C51-C58 Malignant neoplasms of female genital organs	0.016	0.984	0.000
C62.1 Descended testis	0.016	0.984	0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.016	0.984	0.000
C60.9 Penis, unspecified	0.016	0.984	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.015	0.984	0.000
D41.0 Kidney	0.016	0.984	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.015	0.985	0.000
C71.8 Overlapping lesion of brain	0.015	0.985	0.000
C71.9 Brain, unspecified	0.015	0.985	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.015	0.985	0.000
C70 Malignant neoplasm of meninges	0.015	0.985	0.000
C71.7 Brain stem	0.015	0.985	0.000
C71.6 Cerebellum	0.015	0.985	0.000
C71.5 Cerebral ventricle	0.015	0.985	0.000
Z85.5 Personal history of malignant neoplasm of urinary tract	0.015	0.985	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.015	0.985	0.000
C60.8 Overlapping lesion of penis	0.015	0.985	0.000
C60.2 Body of penis	0.015	0.985	0.000
C60.1 Glans penis	0.015	0.985	0.000
C60.0 Prepuce	0.015	0.985	0.000
C54 Malignant neoplasm of corpus uteri	0.015	0.985	0.000
C62.0 Undescended testis	0.015	0.985	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.014	0.985	0.000
C53 Malignant neoplasm of cervix uteri	0.014	0.986	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.014	0.986	0.000
C63.9 Male genital organ, unspecified	0.014	0.986	0.000
C63.8 Overlapping lesion of male genital organs	0.014	0.986	0.000
C63.7 Other specified male genital organs	0.014	0.986	0.000
C63.2 Scrotum	0.014	0.986	0.000
C63.1 Spermatic cord	0.014	0.986	0.000
C63.0 Epididymis	0.014	0.986	0.000
M21.7 Unequal limb length (acquired)	0.014	0.986	0.000
C07 Malignant neoplasm of parotid gland	0.014	0.986	0.000
C54.1 Endometrium	0.014	0.986	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.014	0.986	0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.014	0.986	0.000
C46 Kaposi's sarcoma	0.014	0.986	0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.014	0.986	0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.014	0.986	0.000
C62.9 Testis, unspecified	0.014	0.986	0.000
M21.4 Flat foot [pes planus] (acquired)	0.014	0.986	0.000
C53.9 Cervix uteri, unspecified	0.014	0.986	0.000
C97 Malignant neoplasms of independent (primary) multiple sites	0.014	0.986	0.000
M23.3 Other meniscus derangements	0.014	0.986	0.000
C45.7 Mesothelioma of other sites	0.014	0.986	0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.013	0.987	0.000
M23.07 Cystic meniscus-Capsular lig	0.013	0.987	0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.013	0.987	0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.013	0.987	0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.013	0.987	0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.013	0.987	0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.013	0.987	0.000
M23.00 Cystic meniscus (Multiple sites)	0.013	0.987	0.000
C45.0 Mesothelioma of pleura	0.013	0.987	0.000
C09 Malignant neoplasm of tonsil	0.013	0.987	0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.013	0.987	0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.013	0.987	0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.013	0.987	0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.013	0.987	0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.013	0.987	0.000
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.013	0.987	0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.013	0.987	0.000
C69.9 Eye, unspecified	0.013	0.987	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.013	0.987	0.000
M21.9 Acquired deformity of limb, unspecified	0.013	0.987	0.000
M21.8 Other specified acquired deformities of limbs	0.013	0.987	0.000
C00 Malignant neoplasm of lip	0.013	0.987	0.000
C71.2 Temporal lobe	0.013	0.987	0.000
C45.9 Mesothelioma, unspecified	0.013	0.987	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.013	0.987	0.000
C48.1 Specified parts of peritoneum	0.013	0.987	0.000
C49.9 Connective and soft tissue, unspecified	0.013	0.987	0.000
C05 Malignant neoplasm of palate	0.013	0.987	0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.013	0.987	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.013	0.987	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.013	0.987	0.000
C69.3 Choroid	0.012	0.987	0.000
D44.6 Carotid body	0.012	0.987	0.000
C75 Malignant neoplasm of other endocrine glands and related structures	0.012	0.988	0.000
M23.47 Loose body in knee-Capsular lig	0.012	0.988	0.000
M23.46 Loose body in knee-O/unsp lat men	0.012	0.988	0.000
M23.45 Loose body in knee-Pst hrn lat men	0.012	0.988	0.000
M23.44 Loose body in knee-Lat lig/ant men	0.012	0.988	0.000
M23.43 Loose body in knee-Med lig/oth men	0.012	0.988	0.000
M23.42 Loose body in knee-Pst lig/hrn men	0.012	0.988	0.000
M23.41 Loose body in knee-Ant lig/hrn men	0.012	0.988	0.000
M23.40 Loose body in knee-Mult sites	0.012	0.988	0.000
C13 Malignant neoplasm of hypopharynx	0.012	0.988	0.000
C11 Malignant neoplasm of nasopharynx	0.012	0.988	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.012	0.988	0.000
C03 Malignant neoplasm of gum	0.012	0.988	0.000
C12 Malignant neoplasm of pyriform sinus	0.012	0.988	0.000
C48.2 Peritoneum, unspecified	0.012	0.988	0.000
C04 Malignant neoplasm of floor of mouth	0.012	0.988	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.012	0.988	0.000
C45.2 Mesothelioma of pericardium	0.012	0.988	0.000
C45.1 Mesothelioma of peritoneum	0.012	0.988	0.000
C69.8 Overlapping lesion of eye and adnexa	0.012	0.988	0.000
C69.6 Orbit	0.012	0.988	0.000
C69.5 Lachrymal gland and duct	0.012	0.988	0.000
C69.4 Ciliary body	0.012	0.988	0.000
C69.2 Retina	0.012	0.988	0.000
C69.1 Cornea	0.012	0.988	0.000
C69.0 Conjunctiva	0.012	0.988	0.000
C08.9 Major salivary gland, unspecified	0.012	0.988	0.000
C49.5 Connective and soft tissue of pelvis	0.012	0.988	0.000
D44.3 Pituitary gland	0.012	0.988	0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.012	0.988	0.000
M23.17 Discoid meniscus (congenital)-Capsular lig	0.012	0.988	0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.012	0.988	0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.012	0.988	0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.012	0.988	0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.012	0.988	0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.012	0.988	0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.012	0.988	0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.012	0.988	0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.012	0.988	0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.012	0.988	0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.012	0.988	0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.012	0.988	0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.012	0.988	0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.012	0.988	0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.012	0.988	0.000
D38.0 Larynx	0.012	0.988	0.000
C73 Malignant neoplasm of thyroid gland	0.012	0.988	0.000
C74 Malignant neoplasm of adrenal gland	0.012	0.988	0.000
C57 Malignant neoplasm of other and unspecified female genital organs	0.012	0.988	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.012	0.988	0.000
C10 Malignant neoplasm of oropharynx	0.012	0.988	0.000
M21.76 Unequal limb length (acquired) (Lower leg)	0.012	0.988	0.000
M23.49 Loose body in knee-Unspec lig/men	0.012	0.988	0.000
C58 Malignant neoplasm of placenta	0.012	0.988	0.000
D46 Myelodysplastic syndromes	0.012	0.988	0.000
C52 Malignant neoplasm of vagina	0.011	0.988	0.000
C48.8 Overlapping lesion of retroperitoneum and peritoneum	0.011	0.988	0.000
C48.0 Retroperitoneum	0.011	0.989	0.000
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)	0.011	0.989	0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites	0.011	0.989	0.000
C40 Malignant neoplasm of bone and articular cartilage of limbs	0.011	0.989	0.000
D41.9 Urinary organ, unspecified	0.011	0.989	0.000
D41.7 Other urinary organs	0.011	0.989	0.000
D41.3 Urethra	0.011	0.989	0.000
D41.2 Ureter	0.011	0.989	0.000
D41.1 Renal pelvis	0.011	0.989	0.000
C70.9 Meninges, unspecified	0.011	0.989	0.000
C70.1 Spinal meninges	0.011	0.989	0.000
C70.0 Cerebral meninges	0.011	0.989	0.000
C72.9 Central nervous system, unspecified	0.011	0.989	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.011	0.989	0.000
C72.5 Other and unspecified cranial nerves	0.011	0.989	0.000
C72.4 Acoustic nerve	0.011	0.989	0.000
C72.3 Optic nerve	0.011	0.989	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations