TreeWAS – Variant ID: rs4819143

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
F05.9 Delirium, unspecified	0.000	0.982	0.018
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.982	0.018
F00 Dementia in Alzheimer's disease	0.000	0.984	0.016
F05 Delirium, not induced by alcohol and other psychoactive substances	0.000	0.985	0.015
F00.0 Dementia in Alzheimer's disease with early onset	0.000	0.986	0.014
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.000	0.987	0.013
F05.0 Delirium not superimposed on dementia, so described	0.000	0.988	0.012
Z63.4 Disappearance and death of family member	0.000	0.988	0.012
F05.1 Delirium superimposed on dementia	0.000	0.988	0.012
F00-F09 Organic, including symptomatic, mental disorders	0.000	0.988	0.012
F05.8 Other delirium	0.000	0.988	0.012
Z63.0 Problems in relationship with spouse or partner	0.000	0.988	0.012
F00.1 Dementia in Alzheimer's disease with late onset	0.000	0.988	0.011
Z63 Other problems related to primary support group, including family circumstances	0.000	0.988	0.012
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.000	0.990	0.010
F02 Dementia in other diseases classified elsewhere	0.000	0.991	0.009
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.000	0.991	0.009
Z63.7 Other stressful life events affecting family and household	0.000	0.991	0.009
Z63.5 Disruption of family by separation and divorce	0.000	0.991	0.009
Z63.8 Other specified problems related to primary support group	0.000	0.991	0.009
F01 Vascular dementia	0.000	0.991	0.009
Z63.6 Dependent relative needing care at home	0.000	0.991	0.008
Z63.9 Problem related to primary support group, unspecified	0.000	0.991	0.008
Z63.3 Absence of family member	0.000	0.991	0.008
Z63.2 Inadequate family support	0.000	0.991	0.008
Z63.1 Problems in relationship with parents and in-laws	0.000	0.991	0.008
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.000	0.992	0.008
F02.3 Dementia in Parkinson's disease	0.000	0.992	0.008
F07.2 Postconcussional syndrome	0.000	0.992	0.008
F09 Unspecified organic or symptomatic mental disorder	0.000	0.993	0.007
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.000	0.993	0.007
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.000	0.993	0.007
F07.1 Postencephalitic syndrome	0.000	0.993	0.007
F07.0 Organic personality disorder	0.000	0.993	0.007
N89.8 Other specified noninflammatory disorders of vagina	0.007	0.993	0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.000	0.993	0.007
F02.2 Dementia in Huntington's disease	0.000	0.993	0.007
F02.1 Dementia in Creutzfeldt-Jakob disease	0.000	0.993	0.007
F02.0 Dementia in Pick's disease	0.000	0.993	0.007
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.993	0.007
F01.8 Other vascular dementia	0.000	0.994	0.006
F01.3 Mixed cortical and subcortical vascular dementia	0.000	0.994	0.006
F01.2 Subcortical vascular dementia	0.000	0.994	0.006
F01.1 Multi-infarct dementia	0.000	0.994	0.006
F01.0 Vascular dementia of acute onset	0.000	0.994	0.006
F02.8 Dementia in other specified diseases classified elsewhere	0.000	0.994	0.006
F01.9 Vascular dementia, unspecified	0.000	0.994	0.006
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.000	0.994	0.006
I50.0 Congestive heart failure	0.000	0.994	0.006
H34.8 Other retinal vascular occlusions	0.000	0.994	0.006
Z60.2 Living alone	0.000	0.994	0.006
Z56.0 Unemployment, unspecified	0.000	0.994	0.006
Z56 Problems related to employment and unemployment	0.000	0.994	0.006
Z12.8 Special screening examination for neoplasm of other sites	0.000	0.994	0.006
Z60 Problems related to social environment	0.000	0.994	0.005
I50.9 Heart failure, unspecified	0.000	0.994	0.005
G30.9 Alzheimer's disease, unspecified	0.000	0.995	0.005
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.995	0.005
O70.0 First degree perineal laceration during delivery	0.000	0.995	0.005
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.000	0.995	0.005
F06.6 Organic emotionally labile [asthenic] disorder	0.000	0.995	0.005
F06.5 Organic dissociative disorder	0.000	0.995	0.005
F06.4 Organic anxiety disorder	0.000	0.995	0.005
F06.3 Organic mood [affective] disorders	0.000	0.995	0.005
F06.2 Organic delusional [schizophrenia-like] disorder	0.000	0.995	0.005
F06.1 Organic catatonic disorder	0.000	0.995	0.005
F06.0 Organic hallucinosis	0.000	0.995	0.005
Z57.5 Occupational exposure to toxic agents in other industries	0.000	0.995	0.005
Z03.1 Observation for suspected malignant neoplasm	0.000	0.995	0.005
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.995	0.004
G30.0 Alzheimer's disease with early onset	0.000	0.995	0.005
Z65 Problems related to other psychosocial circumstances	0.000	0.995	0.004
Z62 Other problems related to upbringing	0.000	0.995	0.004
Z55 Problems related to education and literacy	0.000	0.995	0.004
Z57 Occupational exposure to risk-factors	0.000	0.996	0.004
G30 Alzheimer's disease	0.000	0.996	0.004
Z61 Problems related to negative life events in childhood	0.000	0.996	0.004
C50.5 Lower-outer quadrant of breast	0.000	0.996	0.004
Z59 Problems related to housing and economic circumstances	0.000	0.996	0.004
Z64 Problems related to certain psychosocial circumstances	0.000	0.996	0.004
Z56.7 Other and unspecified problems related to employment	0.000	0.996	0.004
Z56.5 Uncongenial work	0.000	0.996	0.004
Z56.4 Discord with boss and workmates	0.000	0.996	0.004
Z56.2 Threat of job loss	0.000	0.996	0.004
Z56.1 Change of job	0.000	0.996	0.004
Z60.5 Target of perceived adverse discrimination and persecution	0.000	0.996	0.004
Z60.4 Social exclusion and rejection	0.000	0.996	0.004
Z60.3 Acculturation difficulty	0.000	0.996	0.004
Z60.1 Atypical parenting situation	0.000	0.996	0.004
Z60.0 Problems of adjustment to life-cycle transitions	0.000	0.996	0.004
S62.20 Fracture of first metacarpal bone (closed)	0.000	0.996	0.004
L81.4 Other melanin hyperpigmentation	0.004	0.996	0.000
I50 Heart failure	0.000	0.996	0.004
Z60.8 Other problems related to social environment	0.000	0.996	0.004
Z56.3 Stressful work schedule	0.000	0.996	0.004
S62.2 Fracture of first metacarpal bone	0.000	0.996	0.004
Z56.6 Other physical and mental strain related to work	0.000	0.996	0.004
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.000	0.996	0.004
S62 Fracture at wrist and hand level	0.000	0.996	0.004
S62.0 Fracture of navicular [scaphoid] bone of hand	0.000	0.996	0.004
H34 Retinal vascular occlusions	0.000	0.996	0.004
H34.2 Other retinal artery occlusions	0.000	0.996	0.004
S62.61 Fracture of other finger (open)	0.000	0.996	0.004
S62.4 Multiple fractures of metacarpal bones	0.000	0.996	0.004
S62.8 Fracture of other and unspecified parts of wrist and hand	0.000	0.996	0.004
N89 Other noninflammatory disorders of vagina	0.004	0.996	0.000
Z55.9 Problems relating to education and literacy, unspecified	0.000	0.996	0.003
Z55.8 Other problems relating to education and literacy	0.000	0.996	0.003
Z55.4 Educational maladjustment and discord with teachers and classmates	0.000	0.996	0.003
Z55.3 Underachievement in school	0.000	0.996	0.003
Z55.2 Failed examinations	0.000	0.996	0.003
Z55.1 Schooling unavailable and unattainable	0.000	0.996	0.003
Z55.0 Illiteracy and low-level literacy	0.000	0.996	0.003
Z62.9 Problem related to upbringing, unspecified	0.000	0.996	0.003
Z62.8 Other specified problems related to upbringing	0.000	0.996	0.003
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.000	0.996	0.003
Z62.5 Other problems related to neglect in upbringing	0.000	0.996	0.003
Z62.4 Emotional neglect of child	0.000	0.996	0.003
Z62.3 Hostility towards and scapegoating of child	0.000	0.996	0.003
Z62.2 Institutional upbringing	0.000	0.996	0.003
Z62.1 Parental overprotection	0.000	0.996	0.003
Z62.0 Inadequate parental supervision and control	0.000	0.996	0.003
Z65.9 Problem related to unspecified psychosocial circumstances	0.000	0.996	0.003
Z65.8 Other specified problems related to psychosocial circumstances	0.000	0.996	0.003
Z65.5 Exposure to disaster, war and other hostilities	0.000	0.996	0.003
Z65.4 Victim of crime and terrorism	0.000	0.996	0.003
Z65.3 Problems related to other legal circumstances	0.000	0.996	0.003
Z65.2 Problems related to release from prison	0.000	0.996	0.003
Z65.1 Imprisonment and other incarceration	0.000	0.996	0.003
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.000	0.996	0.003
Z59.0 Homelessness	0.000	0.996	0.003
S62.40 Multiple fractures of metacarpal bones (closed)	0.000	0.996	0.003
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.000	0.997	0.003
Z57.9 Occupational exposure to unspecified risk-factor	0.000	0.997	0.003
Z57.7 Occupational exposure to vibration	0.000	0.997	0.003
Z57.6 Occupational exposure to extreme temperature	0.000	0.997	0.003
Z57.4 Occupational exposure to toxic agents in agriculture	0.000	0.997	0.003
Z57.1 Occupational exposure to radiation	0.000	0.997	0.003
Z57.0 Occupational exposure to noise	0.000	0.997	0.003
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.000	0.997	0.003
F06.7 Mild cognitive disorder	0.000	0.997	0.003
G30.8 Other Alzheimer's disease	0.000	0.997	0.003
G30.1 Alzheimer's disease with late onset	0.000	0.997	0.003
Z36.9 Antenatal screening, unspecified	0.003	0.997	0.000
Z61.9 Negative life events in childhood, unspecified	0.000	0.997	0.003
Z61.8 Other negative life events in childhood	0.000	0.997	0.003
Z61.7 Personal frightening experience in childhood	0.000	0.997	0.003
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.000	0.997	0.003
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.000	0.997	0.003
Z61.3 Events resulting in loss of self-esteem in childhood	0.000	0.997	0.003
Z61.2 Altered pattern of family relationships in childhood	0.000	0.997	0.003
Z61.1 Removal from home in childhood	0.000	0.997	0.003
Z61.0 Loss of love relationship in childhood	0.000	0.997	0.003
Z59.7 Insufficient social insurance and welfare support	0.000	0.997	0.003
Z59.6 Low income	0.000	0.997	0.003
Z59.5 Extreme poverty	0.000	0.997	0.003
Z59.3 Problems related to living in residential institution	0.000	0.997	0.003
Z59.2 Discord with neighbours, lodgers and landlord	0.000	0.997	0.003
Z59.1 Inadequate housing	0.000	0.997	0.003
Z64.4 Discord with counsellors	0.000	0.997	0.003
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.000	0.997	0.003
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.000	0.997	0.003
Z64.1 Problems related to multiparity	0.000	0.997	0.003
Z36.0 Antenatal screening for chromosomal anomalies	0.003	0.997	0.000
Z60.9 Problem related to social environment, unspecified	0.000	0.997	0.003
Z58 Problems related to physical environment	0.000	0.997	0.003
S62.6 Fracture of other finger	0.000	0.997	0.003
Z57.3 Occupational exposure to other air contaminants	0.000	0.997	0.003
Z59.8 Other problems relating to housing and economic circumstances	0.000	0.997	0.003
S62.1 Fracture of other carpal bone(s)	0.000	0.997	0.003
N89.5 Stricture and atresia of vagina	0.003	0.997	0.000
Z61.6 Problems related to alleged physical abuse of child	0.000	0.997	0.003
H34.1 Central retinal artery occlusion	0.000	0.997	0.003
S62.21 Fracture of first metacarpal bone (open)	0.000	0.997	0.003
N89.0 Mild vaginal dysplasia	0.003	0.997	0.000
I38 Endocarditis, valve unspecified	0.000	0.997	0.003
N89.3 Dysplasia of vagina, unspecified	0.003	0.997	0.000
S62.7 Multiple fractures of fingers	0.000	0.997	0.003
Z64.0 Problems related to unwanted pregnancy	0.000	0.997	0.003
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.000	0.997	0.003
H34.0 Transient retinal artery occlusion	0.000	0.997	0.003
Z36 Antenatal screening	0.003	0.997	0.000
H92.0 Otalgia	0.003	0.997	0.000
Z57.8 Occupational exposure to other risk-factors	0.000	0.997	0.003
Z59.4 Lack of adequate food	0.000	0.997	0.003
N89.1 Moderate vaginal dysplasia	0.003	0.997	0.000
I42.0 Dilated cardiomyopathy	0.000	0.997	0.003
S62.41 Multiple fractures of metacarpal bones (open)	0.000	0.997	0.003
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.000	0.997	0.003
H92.1 Otorrhoea	0.003	0.997	0.000
S62.10 Fracture of other carpal bone(s) (closed)	0.000	0.997	0.003
N89.7 Haematocolpos	0.003	0.997	0.000
N89.4 Leukoplakia of vagina	0.003	0.997	0.000
N89.2 Severe vaginal dysplasia, not elsewhere classified	0.003	0.997	0.000
S62.5 Fracture of thumb	0.000	0.997	0.003
Z36.2 Other antenatal screening based on amniocentesis	0.003	0.997	0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.003	0.997	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.003	0.997	0.000
S62.71 Multiple fractures of fingers (open)	0.000	0.997	0.003
S62.3 Fracture of other metacarpal bone	0.000	0.997	0.003
H53.2 Diplopia	0.000	0.997	0.003
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.003	0.997	0.000
H34.9 Retinal vascular occlusion, unspecified	0.000	0.997	0.003
N89.9 Noninflammatory disorder of vagina, unspecified	0.003	0.997	0.000
C67.3 Anterior wall of bladder	0.000	0.997	0.003
L81.8 Other specified disorders of pigmentation	0.003	0.997	0.000
D52.9 Folate deficiency anaemia, unspecified	0.003	0.997	0.000
R94.3 Abnormal results of cardiovascular function studies	0.000	0.997	0.003
S50.9 Superficial injury of forearm, unspecified	0.000	0.997	0.003
Z58.9 Problem related to physical environment, unspecified	0.000	0.997	0.002
Z58.6 Inadequate drinking-water supply	0.000	0.997	0.002
Z58.4 Exposure to radiation	0.000	0.997	0.002
Z58.3 Exposure to soil pollution	0.000	0.997	0.002
Z58.2 Exposure to water pollution	0.000	0.997	0.002
Z58.0 Exposure to noise	0.000	0.997	0.002
S62.11 Fracture of other carpal bone(s) (open)	0.000	0.997	0.002
Q23.1 Congenital insufficiency of aortic valve	0.000	0.997	0.003
Z58.7 Exposure to tobacco smoke	0.000	0.997	0.002
C67.9 Bladder, unspecified	0.000	0.997	0.003
Z11.0 Special screening examination for intestinal infectious diseases	0.003	0.997	0.000
Z58.1 Exposure to air pollution	0.000	0.997	0.002
L81 Other disorders of pigmentation	0.002	0.998	0.000
S62.31 Fracture of other metacarpal bone (open)	0.000	0.998	0.002
M25.86 Other specified joint disorders (Lower leg)	0.000	0.998	0.002
Z58.5 Exposure to other pollution	0.000	0.998	0.002
C67.5 Bladder neck	0.000	0.998	0.002
Z36.5 Antenatal screening for isoimmunisation	0.002	0.998	0.000
F03 Unspecified dementia	0.000	0.998	0.002
Z03.4 Observation for suspected myocardial infarction	0.000	0.998	0.002
H92 Otalgia and effusion of ear	0.002	0.998	0.000
S62.50 Fracture of thumb (closed)	0.000	0.998	0.002
I42.2 Other hypertrophic cardiomyopathy	0.000	0.998	0.002
M34.9 Systemic sclerosis, unspecified	0.002	0.998	0.000
T93.2 Sequelae of other fractures of lower limb	0.002	0.998	0.000
S72.10 Pertrochanteric fracture (closed)	0.000	0.998	0.002
H53.9 Visual disturbance, unspecified	0.000	0.998	0.002
G93.0 Cerebral cysts	0.000	0.998	0.002
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.998	0.002
S50.0 Contusion of elbow	0.000	0.998	0.002
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.998	0.002
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.002	0.998	0.000
L53.8 Other specified erythematous conditions	0.002	0.998	0.000
Z30.1 Insertion of (intra-uterine) contraceptive device	0.002	0.998	0.000
E83.3 Disorders of phosphorus metabolism	0.000	0.998	0.002
L81.0 Postinflammatory hyperpigmentation	0.002	0.998	0.000
C67 Malignant neoplasm of bladder	0.000	0.998	0.002
Z58.8 Other problems related to physical environment	0.000	0.998	0.002
F33.9 Recurrent depressive disorder, unspecified	0.000	0.998	0.002
S62.70 Multiple fractures of fingers (closed)	0.000	0.998	0.002
M25.84 Other specified joint disorders (Hand)	0.000	0.998	0.002
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.998	0.002
M79.10 Myalgia (Multiple sites)	0.002	0.998	0.000
C67.2 Lateral wall of bladder	0.000	0.998	0.002
L81.7 Pigmented purpuric dermatosis	0.002	0.998	0.000
L81.6 Other disorders of diminished melanin formation	0.002	0.998	0.000
L81.5 Leukoderma, not elsewhere classified	0.002	0.998	0.000
L81.3 Cafe au lait spots	0.002	0.998	0.000
L81.1 Chloasma	0.002	0.998	0.000
S91.3 Open wound of other parts of foot	0.002	0.998	0.000
C78.7 Secondary malignant neoplasm of liver	0.002	0.998	0.000
J95.0 Tracheostomy malfunction	0.002	0.998	0.000
H92.2 Otorrhagia	0.002	0.998	0.000
L03.9 Cellulitis, unspecified	0.000	0.998	0.002
L81.2 Freckles	0.002	0.998	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.998	0.002
K35.8 Acute appendicitis, other and unspecified	0.000	0.998	0.002
S50 Superficial injury of forearm	0.000	0.998	0.002
O70.9 Perineal laceration during delivery, unspecified	0.000	0.998	0.002
Z03.9 Observation for suspected disease or condition, unspecified	0.000	0.998	0.002
M34.8 Other forms of systemic sclerosis	0.002	0.998	0.000
N89.6 Tight hymenal ring	0.002	0.998	0.000
S62.51 Fracture of thumb (open)	0.000	0.998	0.002
J95.8 Other postprocedural respiratory disorders	0.002	0.998	0.000
O70 Perineal laceration during delivery	0.000	0.998	0.002
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.002	0.998	0.000
R22.2 Localised swelling, mass and lump, trunk	0.002	0.998	0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.002	0.998	0.000
C21.1 Anal canal	0.002	0.998	0.000
C67.7 Urachus	0.000	0.998	0.002
H11.0 Pterygium	0.000	0.998	0.002
Z11.2 Special screening examination for other bacterial diseases	0.002	0.998	0.000
H66.3 Other chronic suppurative otitis media	0.002	0.998	0.000
M25.8 Other specified joint disorders	0.000	0.998	0.002
K56.1 Intussusception	0.000	0.998	0.002
M25.83 Other specified joint disorders (Forearm)	0.000	0.998	0.002
C21.0 Anus, unspecified	0.002	0.998	0.000
Z36.8 Other antenatal screening	0.002	0.998	0.000
M34 Systemic sclerosis	0.002	0.998	0.000
I42 Cardiomyopathy	0.000	0.998	0.002
C67.8 Overlapping lesion of bladder	0.000	0.998	0.002
Z03 Medical observation and evaluation for suspected diseases and conditions	0.000	0.998	0.002
S50.1 Contusion of other and unspecified parts of forearm	0.000	0.998	0.002
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.002	0.998	0.000
Q23 Congenital malformations of aortic and mitral valves	0.000	0.998	0.002
C67.4 Posterior wall of bladder	0.000	0.998	0.002
K08.9 Disorder of teeth and supporting structures, unspecified	0.000	0.998	0.002
S50.7 Multiple superficial injuries of forearm	0.000	0.998	0.002
S82.31 Fracture of lower end of tibia (open)	0.002	0.998	0.000
M34.1 CR(E)ST syndrome	0.002	0.998	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.002	0.998	0.000
C49.9 Connective and soft tissue, unspecified	0.000	0.998	0.002
M70.46 Prepatellar bursitis-Lower Leg	0.002	0.998	0.000
M79.15 Myalgia (Pelvic region and thigh)	0.002	0.998	0.000
M34.0 Progressive systemic sclerosis	0.002	0.998	0.000
J95.5 Postprocedural subglottic stenosis	0.002	0.998	0.000
Q23.0 Congenital stenosis of aortic valve	0.000	0.998	0.002
M07.39 Other psoriatic arthropathies (Site unspecified)	0.002	0.998	0.000
S92.41 Fracture of great toe (open)	0.002	0.998	0.000
M75.5 Bursitis of shoulder	0.000	0.998	0.002
O70.3 Fourth degree perineal laceration during delivery	0.000	0.998	0.001
F33 Recurrent depressive disorder	0.000	0.998	0.002
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.998	0.002
Q24.8 Other specified congenital malformations of heart	0.000	0.998	0.002
M25.89 Other specified joint disorders (Site unspecified)	0.000	0.998	0.001
M25.82 Other specified joint disorders (Upper arm)	0.000	0.998	0.001
M25.80 Other specified joint disorders (Multiple sites)	0.000	0.998	0.001
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.998	0.002
C21.8 Overlapping lesion of rectum, anus and anal canal	0.002	0.998	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.998	0.002
R85.5 Abnormal microbiological findings	0.002	0.998	0.000
I42.9 Cardiomyopathy, unspecified	0.000	0.998	0.002
J13 Pneumonia due to Streptococcus pneumoniae	0.000	0.998	0.002
I42.5 Other restrictive cardiomyopathy	0.000	0.998	0.001
I42.4 Endocardial fibroelastosis	0.000	0.998	0.001
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.998	0.001
M34.2 Systemic sclerosis induced by drugs and chemicals	0.001	0.998	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.000	0.998	0.001
Z03.0 Observation for suspected tuberculosis	0.000	0.998	0.001
D09.0 Bladder	0.000	0.998	0.002
J95.9 Postprocedural respiratory disorder, unspecified	0.001	0.998	0.000
C21 Malignant neoplasm of anus and anal canal	0.002	0.998	0.000
G93.2 Benign intracranial hypertension	0.000	0.998	0.001
H11.9 Disorder of conjunctiva, unspecified	0.000	0.998	0.001
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.000	0.998	0.001
Q23.8 Other congenital malformations of aortic and mitral valves	0.000	0.998	0.001
Q23.4 Hypoplastic left heart syndrome	0.000	0.998	0.001
Q23.3 Congenital mitral insufficiency	0.000	0.998	0.001
Q23.2 Congenital mitral stenosis	0.000	0.998	0.001
S50.8 Other superficial injuries of forearm	0.000	0.998	0.001
C67.0 Trigone of bladder	0.000	0.999	0.001
T78.4 Allergy, unspecified	0.001	0.999	0.000
J95.4 Mendelson's syndrome	0.001	0.999	0.000
J95.3 Chronic pulmonary insufficiency following surgery	0.001	0.999	0.000
J95.2 Acute pulmonary insufficiency following nonthoracic surgery	0.001	0.999	0.000
J95.1 Acute pulmonary insufficiency following thoracic surgery	0.001	0.999	0.000
L43.9 Lichen planus, unspecified	0.000	0.999	0.001
L81.9 Disorder of pigmentation, unspecified	0.001	0.999	0.000
Z74.0 Reduced mobility	0.000	0.999	0.001
G30-G32 Other degenerative diseases of the nervous system	0.000	0.999	0.001
G54.8 Other nerve root and plexus disorders	0.001	0.999	0.000
C67.6 Ureteric orifice	0.000	0.999	0.001
H35.7 Separation of retinal layers	0.001	0.999	0.000
T78.2 Anaphylactic shock, unspecified	0.001	0.999	0.000
F33.8 Other recurrent depressive disorders	0.000	0.999	0.001
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.999	0.001
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.999	0.001
J17.0 Pneumonia in bacterial diseases classified elsewhere	0.000	0.999	0.001
M79.1 Myalgia	0.001	0.999	0.000
Z57.2 Occupational exposure to dust	0.000	0.999	0.001
M79.19 Myalgia (Site unspecified)	0.001	0.999	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.999	0.001
N36.8 Other specified disorders of urethra	0.000	0.999	0.001
T85.2 Mechanical complication of intraocular lens	0.000	0.999	0.001
Z03.5 Observation for other suspected cardiovascular diseases	0.000	0.999	0.001
M25.57 Pain in joint (Ankle and foot)	0.001	0.999	0.000
C67.1 Dome of bladder	0.000	0.999	0.001
G71.0 Muscular dystrophy	0.000	0.999	0.001
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.999	0.001
C21.2 Cloacogenic zone	0.001	0.999	0.000
C49.0 Connective and soft tissue of head, face and neck	0.000	0.999	0.001
O47.9 False labour, unspecified	0.000	0.999	0.001
Z03.2 Observation for suspected mental and behavioural disorders	0.000	0.999	0.001
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.999	0.001
Q61.2 Polycystic kidney, adult type	0.000	0.999	0.001
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.001	0.999	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.000	0.999	0.001
M77.12 Lateral epicondylitis (Upper arm)	0.001	0.999	0.000
K63.3 Ulcer of intestine	0.000	0.999	0.001
M25.88 Other specified joint disorders (Other)	0.000	0.999	0.001
G54.6 Phantom limb syndrome with pain	0.001	0.999	0.000
K56.7 Ileus, unspecified	0.000	0.999	0.001
Z03.3 Observation for suspected nervous system disorder	0.000	0.999	0.001
D52 Folate deficiency anaemia	0.001	0.999	0.000
H11 Other disorders of conjunctiva	0.000	0.999	0.001
M79.17 Myalgia (Ankle and foot)	0.001	0.999	0.000
M79.14 Myalgia (Hand)	0.001	0.999	0.000
M79.13 Myalgia (Forearm)	0.001	0.999	0.000
M79.12 Myalgia (Upper arm)	0.001	0.999	0.000
C49.3 Connective and soft tissue of thorax	0.000	0.999	0.001
G54.1 Lumbosacral plexus disorders	0.001	0.999	0.000
I42.6 Alcoholic cardiomyopathy	0.000	0.999	0.001
J17.3 Pneumonia in parasitic diseases	0.000	0.999	0.001
S05.1 Contusion of eyeball and orbital tissues	0.000	0.999	0.001
S72.1 Pertrochanteric fracture	0.000	0.999	0.001
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.001	0.999	0.000
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.001	0.999	0.000
Z11 Special screening examination for infectious and parasitic diseases	0.001	0.999	0.000
M79.11 Myalgia (Shoulder region)	0.001	0.999	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.000	0.999	0.001
C49.4 Connective and soft tissue of abdomen	0.000	0.999	0.001
C49.1 Connective and soft tissue of upper limb, including shoulder	0.000	0.999	0.001
G54.0 Brachial plexus disorders	0.001	0.999	0.000
H61.0 Perichondritis of external ear	0.001	0.999	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.000	0.999	0.001
C49.8 Overlapping lesion of connective and soft tissue	0.000	0.999	0.001
C49.6 Connective and soft tissue of trunk, unspecified	0.000	0.999	0.001
C49.5 Connective and soft tissue of pelvis	0.000	0.999	0.001
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.999	0.001
H54.0 Blindness, both eyes	0.001	0.999	0.000
O70.1 Second degree perineal laceration during delivery	0.000	0.999	0.001
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.999	0.001
M24.26 Disorder of ligament (Lower leg)	0.000	0.999	0.001
G54.4 Lumbosacral root disorders, not elsewhere classified	0.001	0.999	0.000
K56.2 Volvulus	0.000	0.999	0.001
G54 Nerve root and plexus disorders	0.001	0.999	0.000
D52.8 Other folate deficiency anaemias	0.001	0.999	0.000
D52.1 Drug-induced folate deficiency anaemia	0.001	0.999	0.000
D52.0 Dietary folate deficiency anaemia	0.001	0.999	0.000
G93.3 Postviral fatigue syndrome	0.000	0.999	0.001
H11.1 Conjunctival degenerations and deposits	0.000	0.999	0.001
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.999	0.001
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.999	0.001
D45 Polycythaemia vera	0.001	0.999	0.000
I62 Other nontraumatic intracranial haemorrhage	0.000	0.999	0.001
S72.11 Pertrochanteric fracture (open)	0.000	0.999	0.001
C49.2 Connective and soft tissue of lower limb, including hip	0.000	0.999	0.001
G54.2 Cervical root disorders, not elsewhere classified	0.001	0.999	0.000
K86.3 Pseudocyst of pancreas	0.001	0.999	0.000
M93.9 Osteochondropathy, unspecified	0.000	0.999	0.001
Z11.8 Special screening examination for other infectious and parasitic diseases	0.001	0.999	0.000
Z11.6 Special screening examination for other protozoal diseases and helminthiases	0.001	0.999	0.000
Z11.3 Special screening examination for infections with a predominantly sexual mode of transmission	0.001	0.999	0.000
G93 Other disorders of brain	0.000	0.999	0.001
T78 Adverse effects, not elsewhere classified	0.001	0.999	0.000
M43.02 Spondylolysis (Cervical region)	0.001	0.999	0.000
J17 Pneumonia in diseases classified elsewhere	0.000	0.999	0.001
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.001	0.999	0.000
S62.60 Fracture of other finger (closed)	0.000	0.999	0.001
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.000	0.999	0.001
G54.7 Phantom limb syndrome without pain	0.001	0.999	0.000
G54.5 Neuralgic amyotrophy	0.001	0.999	0.000
G54.3 Thoracic root disorders, not elsewhere classified	0.001	0.999	0.000
H11.2 Conjunctival scars	0.000	0.999	0.001
J30.4 Allergic rhinitis, unspecified	0.000	0.999	0.001
L21.9 Seborrhoeic dermatitis, unspecified	0.000	0.999	0.001
R85.7 Abnormal histological findings	0.001	0.999	0.000
M13.09 Polyarthritis, unspecified (Site unspecified)	0.001	0.999	0.000
J17.2 Pneumonia in mycoses	0.000	0.999	0.001
L28.0 Lichen simplex chronicus	0.000	0.999	0.001
R27.8 Other and unspecified lack of coordination	0.000	0.999	0.001
T25.0 Burn of unspecified degree of ankle and foot	0.001	0.999	0.000
M79.18 Myalgia (Other)	0.001	0.999	0.000
S92.40 Fracture of great toe (closed)	0.001	0.999	0.000
G93.7 Reye's syndrome	0.000	0.999	0.001
I62.1 Nontraumatic extradural haemorrhage	0.000	0.999	0.001
T78.9 Adverse effect, unspecified	0.001	0.999	0.000
Z03.6 Observation for suspected toxic effect from ingested substance	0.001	0.999	0.001
Z71.1 Person with feared complaint in whom no diagnosis is made	0.000	0.999	0.001
M79.16 Myalgia (Lower leg)	0.001	0.999	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.999	0.001
F42.9 Obsessive-compulsive disorder, unspecified	0.001	0.999	0.000
J17.8 Pneumonia in other diseases classified elsewhere	0.000	0.999	0.001
J17.1 Pneumonia in viral diseases classified elsewhere	0.000	0.999	0.001
O70.2 Third degree perineal laceration during delivery	0.000	0.999	0.001
T78.1 Other adverse food reactions, not elsewhere classified	0.001	0.999	0.000
K35 Acute appendicitis	0.000	0.999	0.001
D47.4 Osteomyelofibrosis	0.001	0.999	0.000
F42.0 Predominantly obsessional thoughts or ruminations	0.001	0.999	0.000
G31.2 Degeneration of nervous system due to alcohol	0.000	0.999	0.001
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.000	0.999	0.001
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.000	0.999	0.001
T78.3 Angioneurotic oedema	0.001	0.999	0.000
Z11.1 Special screening examination for respiratory tuberculosis	0.001	0.999	0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.001	0.999	0.000
G93.6 Cerebral oedema	0.000	0.999	0.001
K56.0 Paralytic ileus	0.000	0.999	0.001
R93.6 Abnormal findings on diagnostic imaging of limbs	0.001	0.999	0.000
S92.4 Fracture of great toe	0.001	0.999	0.000
R93 Abnormal findings on diagnostic imaging of other body structures	0.001	0.999	0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.999	0.001
G93.9 Disorder of brain, unspecified	0.000	0.999	0.001
I33.0 Acute and subacute infective endocarditis	0.000	0.999	0.001
I42.8 Other cardiomyopathies	0.000	0.999	0.001
Q24.5 Malformation of coronary vessels	0.000	0.999	0.001
R85.9 Unspecified abnormal finding	0.001	0.999	0.000
R85.6 Abnormal cytological findings	0.001	0.999	0.000
R85.4 Abnormal immunological findings	0.001	0.999	0.000
R85.3 Abnormal level of substances chiefly nonmedicinal as to source	0.001	0.999	0.000
R85.2 Abnormal level of other drugs, medicaments and biological substances	0.001	0.999	0.000
R85.1 Abnormal level of hormones	0.001	0.999	0.000
R85.0 Abnormal level of enzymes	0.001	0.999	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.999	0.001
M25.87 Other specified joint disorders (Ankle and foot)	0.000	0.999	0.001
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.001	0.999	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.000	0.999	0.001
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.999	0.001
G31.0 Circumscribed brain atrophy	0.000	0.999	0.001
K56.3 Gallstone ileus	0.000	0.999	0.001
K83.1 Obstruction of bile duct	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations