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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4854349
log Bayes Factor = 8.30456
Chromosome 2   position 647,861  (GRCh37) Explore rs4854349 on Ensembl!
Variant rs4854349 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E66.9 Obesity, unspecified
1.000 0.000 0.000
E66 Obesity
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
E11.9 Without complications
0.999 0.001 0.000
E66.8 Other obesity
0.999 0.001 0.000
E11.4 With neurological complications
0.993 0.007 0.000
E10-E14 Diabetes mellitus
0.988 0.012 0.000
E65-E68 Obesity and other hyperalimentation
0.977 0.023 0.000
E11.2 With renal complications
0.970 0.030 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.947 0.053 0.000
E11.3 With ophthalmic complications
0.936 0.064 0.000
E10 Insulin-dependent diabetes mellitus
0.911 0.089 0.000
E11.5 With peripheral circulatory complications
0.848 0.152 0.000
E14 Unspecified diabetes mellitus
0.830 0.170 0.000
E65 Localised adiposity
0.824 0.175 0.000
E10.9 Without complications
0.820 0.180 0.000
E66.0 Obesity due to excess calories
0.797 0.203 0.000
E11.8 With unspecified complications
0.796 0.204 0.000
E11.7 With multiple complications
0.753 0.247 0.000
E10.4 With neurological complications
0.737 0.263 0.000
E14.3 With ophthalmic complications
0.737 0.263 0.000
E10.2 With renal complications
0.732 0.268 0.000
E10.0 With coma
0.723 0.277 0.000
E10.8 With unspecified complications
0.722 0.277 0.000
E66.1 Drug-induced obesity
0.717 0.283 0.000
E10.7 With multiple complications
0.715 0.284 0.000
E12 Malnutrition-related diabetes mellitus
0.709 0.291 0.000
E67 Other hyperalimentation
0.700 0.299 0.000
E68 Sequelae of hyperalimentation
0.700 0.299 0.000
E11.1 With ketoacidosis
0.669 0.331 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.660 0.339 0.000
E10.5 With peripheral circulatory complications
0.656 0.344 0.000
E11.6 With other specified complications
0.645 0.355 0.000
E50-E64 Other nutritional deficiencies
0.645 0.355 0.000
E14.6 With other specified complications
0.643 0.357 0.000
E14.1 With ketoacidosis
0.635 0.364 0.000
E13 Other specified diabetes mellitus
0.630 0.370 0.000
E10.6 With other specified complications
0.622 0.377 0.000
E14.5 With peripheral circulatory complications
0.613 0.387 0.000
E14.2 Withrenal complications
0.599 0.401 0.000
E14.8 With unspecified complications
0.597 0.403 0.000
E14.7 With multiple complications
0.595 0.405 0.000
E11.0 With coma
0.591 0.409 0.000
E61 Deficiency of other nutrient elements
0.590 0.410 0.000
E14.0 With coma
0.577 0.423 0.000
E10.3 With ophthalmic complications
0.565 0.435 0.000
E61.1 Iron deficiency
0.553 0.447 0.000
E14.4 With neurological complications
0.529 0.471 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.509 0.491 0.000
E40-E46 Malnutrition
0.509 0.491 0.000
E12.9 Without complications
0.508 0.492 0.000
E12.8 With unspecified complications
0.508 0.492 0.000
E12.7 With multiple complications
0.508 0.492 0.000
E12.6 With other specified complications
0.508 0.492 0.000
E12.5 With peripheral circulatory complications
0.508 0.492 0.000
E12.4 With neurological complications
0.508 0.492 0.000
E12.3 With ophthalmic complications
0.508 0.492 0.000
E12.2 With renal complications
0.508 0.492 0.000
E12.1 With ketoacidosis
0.508 0.492 0.000
E12.0 With coma
0.508 0.492 0.000
E67.8 Other specified hyperalimentation
0.502 0.498 0.000
E67.3 Hypervitaminosis D
0.502 0.498 0.000
E67.2 Megavitamin-B6 syndrome
0.502 0.498 0.000
E67.1 Hypercarotenaemia
0.502 0.498 0.000
E67.0 Hypervitaminosis A
0.502 0.498 0.000
E58 Dietary calcium deficiency
0.494 0.506 0.000
E14.9 Without complications
0.480 0.520 0.000
E54 Ascorbic acid deficiency
0.479 0.521 0.000
I10 Essential (primary) hypertension
0.472 0.528 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.462 0.537 0.000
E50 Vitamin A deficiency
0.462 0.537 0.000
E60 Dietary zinc deficiency
0.462 0.537 0.000
E59 Dietary selenium deficiency
0.462 0.537 0.000
E52 Niacin deficiency [pellagra]
0.462 0.537 0.000
E63 Other nutritional deficiencies
0.452 0.547 0.000
E13.8 With unspecified complications
0.452 0.548 0.000
E13.7 With multiple complications
0.452 0.548 0.000
E13.6 With other specified complications
0.452 0.548 0.000
E13.5 With peripheral circulatory complications
0.452 0.548 0.000
E13.4 With neurological complications
0.452 0.548 0.000
E13.2 With renal complications
0.452 0.548 0.000
E13.1 With ketoacidosis
0.452 0.548 0.000
E13.0 With coma
0.452 0.548 0.000
E56 Other vitamin deficiencies
0.438 0.561 0.000
E51 Thiamine deficiency
0.438 0.561 0.000
E13.3 With ophthalmic complications
0.431 0.569 0.000
E61.9 Deficiency of nutrient element, unspecified
0.423 0.577 0.000
E61.8 Deficiency of other specified nutrient elements
0.423 0.577 0.000
E61.7 Deficiency of multiple nutrient elements
0.423 0.577 0.000
E61.6 Vanadium deficiency
0.423 0.577 0.000
E61.5 Molybdenum deficiency
0.423 0.577 0.000
E61.4 Chromium deficiency
0.423 0.577 0.000
E61.3 Manganese deficiency
0.423 0.577 0.000
E61.0 Copper deficiency
0.423 0.577 0.000
E61.2 Magnesium deficiency
0.411 0.588 0.000
E13.9 Without complications
0.400 0.600 0.000
E15 Nondiabetic hypoglycaemic coma
0.365 0.635 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.365 0.635 0.000
E45 Retarded development following protein-energy malnutrition
0.365 0.635 0.000
E43 Unspecified severe protein-energy malnutrition
0.365 0.635 0.000
E42 Marasmic kwashiorkor
0.365 0.635 0.000
E41 Nutritional marasmus
0.365 0.635 0.000
E40 Kwashiorkor
0.365 0.635 0.000
E10.1 With ketoacidosis
0.347 0.652 0.000
I10-I15 Hypertensive diseases
0.345 0.655 0.000
E55 Vitamin D deficiency
0.332 0.668 0.000
E50.9 Vitamin A deficiency, unspecified
0.332 0.668 0.000
E50.8 Other manifestations of vitamin A deficiency
0.332 0.668 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.332 0.668 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.332 0.668 0.000
E50.5 Vitamin A deficiency with night blindness
0.332 0.668 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.332 0.668 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.332 0.668 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.332 0.668 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.332 0.668 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.332 0.668 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.332 0.668 0.000
E64.8 Sequelae of other nutritional deficiencies
0.332 0.668 0.000
E64.3 Sequelae of rickets
0.332 0.668 0.000
E64.2 Sequelae of vitamin C deficiency
0.332 0.668 0.000
E64.1 Sequelae of vitamin A deficiency
0.332 0.668 0.000
E64.0 Sequelae of protein-energy malnutrition
0.332 0.668 0.000
E63.8 Other specified nutritional deficiencies
0.324 0.675 0.000
E63.1 Imbalance of constituents of food intake
0.324 0.675 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.324 0.675 0.000
E56.9 Vitamin deficiency, unspecified
0.314 0.685 0.000
E56.8 Deficiency of other vitamins
0.314 0.685 0.000
E56.0 Deficiency of vitamin E
0.314 0.685 0.000
E63.9 Nutritional deficiency, unspecified
0.314 0.685 0.000
E51.9 Thiamine deficiency, unspecified
0.314 0.685 0.000
E51.8 Other manifestations of thiamine deficiency
0.314 0.685 0.000
E51.1 Beriberi
0.314 0.685 0.000
E56.1 Deficiency of vitamin K
0.291 0.709 0.000
E51.2 Wernicke's encephalopathy
0.290 0.709 0.000
I15 Secondary hypertension
0.285 0.715 0.000
I84.6 Residual haemorrhoidal skin tags
0.267 0.733 0.000
E44.1 Mild protein-energy malnutrition
0.262 0.738 0.000
E44.0 Moderate protein-energy malnutrition
0.262 0.738 0.000
I13 Hypertensive heart and renal disease
0.259 0.741 0.000
I12 Hypertensive renal disease
0.259 0.741 0.000
G56.0 Carpal tunnel syndrome
0.247 0.753 0.000
E55.0 Rickets, active
0.238 0.762 0.000
E53 Deficiency of other B group vitamins
0.233 0.766 0.001
I15.1 Hypertension secondary to other renal disorders
0.231 0.769 0.000
G40-G47 Episodic and paroxysmal disorders
0.226 0.774 0.000
I15.8 Other secondary hypertension
0.225 0.775 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.222 0.778 0.000
G56 Mononeuropathies of upper limb
0.220 0.780 0.000
I15.0 Renovascular hypertension
0.217 0.783 0.000
I12.9 Hypertensive renal disease without renal failure
0.216 0.784 0.000
I84 Haemorrhoids
0.216 0.784 0.000
Chapter VI Diseases of the nervous system
0.215 0.785 0.000
G59.0 Diabetic mononeuropathy
0.214 0.786 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.213 0.787 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.213 0.787 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.213 0.787 0.000
Chapter IX Diseases of the circulatory system
0.212 0.788 0.000
I84.4 External haemorrhoids with other complications
0.209 0.791 0.000
I11 Hypertensive heart disease
0.208 0.791 0.000
G47 Sleep disorders
0.207 0.793 0.000
I85 Oesophageal varices
0.205 0.795 0.000
G47.3 Sleep apnoea
0.202 0.798 0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.202 0.798 0.000
G43 Migraine
0.201 0.799 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.201 0.799 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.200 0.800 0.000
I82 Other venous embolism and thrombosis
0.199 0.801 0.000
I15.9 Seconday hypertension, unspecified
0.196 0.804 0.000
I80 Phlebitis and thrombophlebitis
0.196 0.804 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.195 0.805 0.000
E16 Other disorders of pancreatic internal secretion
0.195 0.805 0.000
E46 Unspecified protein-energy malnutrition
0.194 0.805 0.001
# Top node
0.194 0.806 0.000
G44 Other headache syndromes
0.194 0.806 0.000
G43.1 Migraine with aura [classical migraine]
0.193 0.807 0.000
I85.9 Oesophageal varices without bleeding
0.193 0.807 0.000
I15.2 Hypertension secondary to endocrine disorders
0.192 0.808 0.000
J22 Unspecified acute lower respiratory infection
0.190 0.810 0.000
I89.0 Lymphoedema, not elsewhere classified
0.189 0.811 0.000
G70-G73 Diseases of myoneural junction and muscle
0.189 0.811 0.000
I13.1 Hypertensive heart and renal disease with renal failure
0.187 0.813 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.187 0.813 0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.186 0.814 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.186 0.814 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.184 0.816 0.000
Q60-Q64 Congenital malformations of the urinary system
0.184 0.816 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.183 0.817 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.178 0.822 0.000
I13.9 Hypertensive heart and renal disease, unspecified
0.177 0.823 0.000
Q61 Cystic kidney disease
0.177 0.823 0.000
I82.8 Embolism and thrombosis of other specified veins
0.176 0.824 0.000
Q23 Congenital malformations of aortic and mitral valves
0.175 0.825 0.000
J20-J22 Other acute lower respiratory infections
0.175 0.825 0.000
G44.2 Tension-type headache
0.175 0.825 0.000
G41 Status epilepticus
0.173 0.827 0.000
G56.8 Other mononeuropathies of upper limb
0.171 0.829 0.000
E53.1 Pyridoxine deficiency
0.167 0.832 0.001
E53.0 Riboflavin deficiency
0.167 0.832 0.001
I81 Portal vein thrombosis
0.167 0.832 0.000
Chapter X Diseases of the respiratory system
0.167 0.833 0.000
I84.0 Internal thrombosed haemorrhoids
0.167 0.833 0.000
G43.8 Other migraine
0.166 0.834 0.000
Q61.2 Polycystic kidney, adult type
0.164 0.836 0.000
J00-J06 Acute upper respiratory infections
0.163 0.837 0.000
G56.3 Lesion of radial nerve
0.163 0.837 0.000
Q23.1 Congenital insufficiency of aortic valve
0.162 0.838 0.000
Q61.3 Polycystic kidney, unspecified
0.162 0.838 0.000
Q24 Other congenital malformations of heart
0.161 0.839 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.158 0.842 0.000
G56.1 Other lesions of median nerve
0.158 0.842 0.000
J00 Acute nasopharyngitis [common cold]
0.158 0.842 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.157 0.843 0.000
G45.3 Amaurosis fugax
0.157 0.843 0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.155 0.844 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.155 0.845 0.000
G47.2 Disorders of the sleep-wake schedule
0.155 0.845 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.154 0.846 0.000
I82.3 Embolism and thrombosis of renal vein
0.154 0.846 0.000
G44.4 Drug-induced headache, not elsewhere classified
0.154 0.846 0.000
I12.0 Hypertensive renal disease with renal failure
0.153 0.847 0.000
G59.8 Other mononeuropathies in diseases classified elsewhere
0.153 0.847 0.000
I82.0 Budd-Chiari syndrome
0.153 0.847 0.000
G45.0 Vertebro-basilar artery syndrome
0.153 0.847 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.153 0.847 0.000
G72 Other myopathies
0.152 0.848 0.000
Q35-Q37 Cleft lip and cleft palate
0.152 0.848 0.000
I82.9 Embolism and thrombosis of unspecified vein
0.152 0.848 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.151 0.849 0.000
G70 Myasthenia gravis and other myoneural disorders
0.151 0.849 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.151 0.849 0.000
I88 Nonspecific lymphadenitis
0.150 0.849 0.000
I85.0 Oesophageal varices with bleeding
0.150 0.850 0.000
J06.9 Acute upper respiratory infection, unspecified
0.150 0.850 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.150 0.850 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.150 0.850 0.000
G54 Nerve root and plexus disorders
0.149 0.851 0.000
G52 Disorders of other cranial nerves
0.149 0.851 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.148 0.852 0.000
I89.1 Lymphangitis
0.148 0.852 0.000
Q21 Congenital malformations of cardiac septa
0.148 0.852 0.000
Q00-Q07 Congenital malformations of the nervous system
0.148 0.852 0.000
G71 Primary disorders of muscles
0.147 0.853 0.000
Q80-Q89 Other congenital malformations
0.146 0.854 0.000
G56.4 Causalgia
0.146 0.854 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.146 0.854 0.000
I84.1 Internal haemorrhoids with other complications
0.146 0.854 0.000
G43.3 Complicated migraine
0.145 0.855 0.000
G46.4 Cerebellar stroke syndrome
0.145 0.855 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.145 0.855 0.000
I00-I02 Acute rheumatic fever
0.144 0.856 0.000
G43.0 Migraine without aura [common migraine]
0.144 0.856 0.000
G44.0 Cluster headache syndrome
0.144 0.856 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.144 0.856 0.000
G47.4 Narcolepsy and cataplexy
0.143 0.857 0.000
I05-I09 Chronic rheumatic heart diseases
0.143 0.857 0.000
I82.1 Thrombophlebitis migrans
0.143 0.857 0.000
G30-G32 Other degenerative diseases of the nervous system
0.142 0.858 0.000
G43.2 Status migrainosus
0.142 0.858 0.000
J01 Acute sinusitis
0.142 0.858 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.141 0.859 0.000
G20-G26 Extrapyramidal and movement disorders
0.141 0.859 0.000
I86 Varicose veins of other sites
0.141 0.859 0.000
Q64 Other congenital malformations of urinary system
0.140 0.860 0.000
G44.1 Vascular headache, not elsewhere classified
0.140 0.860 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.140 0.860 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.140 0.860 0.000
E16.4 Abnormal secretion of gastrin
0.140 0.860 0.000
E16.3 Increased secretion of glucagon
0.140 0.860 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.140 0.860 0.000
Q23.0 Congenital stenosis of aortic valve
0.139 0.861 0.000
E53.9 Vitamin B deficiency, unspecified
0.138 0.861 0.001
G45.1 Carotid artery syndrome (hemispheric)
0.138 0.862 0.000
Q26 Congenital malformations of great veins
0.138 0.862 0.000
G44.3 Chronic posttraumatic headache
0.138 0.862 0.000
G46.3 Brain stem stroke syndrome
0.137 0.863 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.137 0.863 0.000
L50-L54 Urticaria and erythema
0.136 0.864 0.000
G46.7 Other lacunar syndromes
0.136 0.864 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.136 0.864 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.136 0.864 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.135 0.865 0.000
G47.8 Other sleep disorders
0.134 0.866 0.000
Q27 Other congenital malformations of peripheral vascular system
0.134 0.866 0.000
G40 Epilepsy
0.133 0.867 0.000
E16.1 Other hypoglycaemia
0.133 0.867 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.133 0.867 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.133 0.867 0.000
Q24.9 Congenital malformation of the heart, unspecified
0.132 0.868 0.000
L20-L30 Dermatitis and eczema
0.132 0.868 0.000
Q23.3 Congenital mitral insufficiency
0.131 0.868 0.000
G46.8 Other vascular syndromes of brain in cerebrovascular diseases
0.131 0.869 0.000
G46.6 Pure sensory lacunar syndrome
0.131 0.869 0.000
G46.5 Pure motor lacunar syndrome
0.131 0.869 0.000
G46.1 Anterior cerebral artery syndrome
0.131 0.869 0.000
G46.0 Middle cerebral artery syndrome
0.131 0.869 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.131 0.869 0.000
G46.2 Posterior cerebral artery syndrome
0.131 0.869 0.000
G41.9 Status epilepticus, unspecified
0.131 0.869 0.000
G45.4 Transient global amnesia
0.130 0.870 0.000
Q50-Q56 Congenital malformations of genital organs
0.130 0.870 0.000
Q66 Congenital deformities of feet
0.129 0.871 0.000
G41.0 Grand mal status epilepticus
0.127 0.873 0.000
Q63 Other congenital malformations of kidney
0.127 0.873 0.000
L60-L75 Disorders of skin appendages
0.127 0.873 0.000
G41.8 Other status epilepticus
0.127 0.873 0.000
Q61.8 Other cystic kidney diseases
0.127 0.873 0.000
Q61.1 Polycystic kidney, infantile type
0.127 0.873 0.000
Q45 Other congenital malformations of digestive system
0.126 0.874 0.000
Q61.4 Renal dysplasia
0.126 0.874 0.000
L73 Other follicular disorders
0.126 0.874 0.000
I88.0 Nonspecific mesenteric lymphadenitis
0.126 0.874 0.000
I82.2 Embolism and thrombosis of vena cava
0.126 0.874 0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified
0.125 0.874 0.000
Q23.8 Other congenital malformations of aortic and mitral valves
0.125 0.874 0.000
Q23.4 Hypoplastic left heart syndrome
0.125 0.874 0.000
Q23.2 Congenital mitral stenosis
0.125 0.874 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.125 0.874 0.000
G71.0 Muscular dystrophy
0.125 0.875 0.000
Q24.6 Congenital heart block
0.125 0.875 0.000
Q31 Congenital malformations of larynx
0.125 0.875 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.124 0.876 0.000
Q21.3 Tetralogy of Fallot
0.124 0.876 0.000
G41.1 Petit mal status epilepticus
0.124 0.876 0.000
G41.2 Complex partial status epilepticus
0.124 0.876 0.000
Q61.5 Medullary cystic kidney
0.123 0.877 0.000
G72.4 Inflammatory myopathy, not elsewhere classified
0.123 0.877 0.000
Q30 Congenital malformations of nose
0.123 0.877 0.000
Q24.8 Other specified congenital malformations of heart
0.122 0.878 0.000
Q24.0 Dextrocardia
0.122 0.878 0.000
Q61.9 Cystic kidney disease, unspecified
0.122 0.878 0.000
Q24.5 Malformation of coronary vessels
0.121 0.879 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.121 0.879 0.000
J21 Acute bronchiolitis
0.121 0.879 0.000
G51 Facial nerve disorders
0.121 0.879 0.000
L29 Pruritus
0.121 0.879 0.000
G63.2 Diabetic polyneuropathy
0.120 0.880 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.120 0.880 0.000
G70.0 Myasthenia gravis
0.120 0.880 0.000
G70.9 Myoneural disorder, unspecified
0.119 0.881 0.000
G62 Other polyneuropathies
0.119 0.881 0.000
M40-M43 Deforming dorsopathies
0.119 0.881 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.119 0.881 0.000
I87 Other disorders of veins
0.119 0.881 0.000
L73.2 Hidradenitis suppurativa
0.119 0.881 0.000
I06 Rheumatic aortic valve diseases
0.119 0.881 0.000
I86.8 Varicose veins of other specified sites
0.119 0.881 0.000
G24 Dystonia
0.119 0.881 0.000
J95-J99 Other diseases of the respiratory system
0.118 0.882 0.000
G54.1 Lumbosacral plexus disorders
0.118 0.882 0.000
Q40 Other congenital malformations of upper alimentary tract
0.118 0.882 0.000
Q21.1 Atrial septal defect
0.117 0.883 0.000
L52 Erythema nodosum
0.117 0.883 0.000
I09 Other rheumatic heart diseases
0.117 0.883 0.000
Q85 Phakomatoses, not elsewhere classified
0.117 0.883 0.000
M43 Other deforming dorsopathies
0.117 0.883 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.116 0.883 0.000
Q37 Cleft palate with cleft lip
0.116 0.884 0.000
G11 Hereditary ataxia
0.116 0.884 0.000
Q24.3 Pulmonary infundibular stenosis
0.115 0.885 0.000
Q24.2 Cor triatriatum
0.115 0.885 0.000
Q24.1 Levocardia
0.115 0.885 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.115 0.885 0.000
Q35 Cleft palate
0.115 0.885 0.000
Q82 Other congenital malformations of skin
0.114 0.885 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.114 0.886 0.000
G72.9 Myopathy, unspecified
0.114 0.886 0.000
J01.9 Acute sinusitis, unspecified
0.114 0.886 0.000
Q61.0 Congenital single renal cyst
0.114 0.886 0.000
Q34 Other congenital malformations of respiratory system
0.114 0.886 0.000
Q33 Congenital malformations of lung
0.114 0.886 0.000
Q32 Congenital malformations of trachea and bronchus
0.114 0.886 0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.113 0.887 0.000
Q65 Congenital deformities of hip
0.113 0.887 0.000
L30 Other dermatitis
0.113 0.887 0.000
M43.1 Spondylolisthesis
0.113 0.887 0.000
G23 Other degenerative diseases of basal ganglia
0.113 0.887 0.000
J20 Acute bronchitis
0.113 0.887 0.000
G72.8 Other specified myopathies
0.112 0.887 0.000
Q89 Other congenital malformations, not elsewhere classified
0.112 0.888 0.000
G54.2 Cervical root disorders, not elsewhere classified
0.112 0.888 0.000
Q28 Other congenital malformations of circulatory system
0.112 0.888 0.000
Q51 Congenital malformations of uterus and cervix
0.112 0.888 0.000
Q74 Other congenital malformations of limb(s)
0.112 0.888 0.000
I88.8 Other nonspecific lymphadenitis
0.112 0.888 0.000
Q64.7 Other congenital malformations of bladder and urethra
0.112 0.888 0.000
G47.9 Sleep disorder, unspecified
0.112 0.888 0.000
G52.3 Disorders of hypoglossal nerve
0.111 0.888 0.000
J06.8 Other acute upper respiratory infections of multiple sites
0.111 0.888 0.000
Q70 Syndactyly
0.111 0.888 0.000
L29.0 Pruritus ani
0.111 0.889 0.000
G10 Huntington's disease
0.111 0.889 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.111 0.889 0.000
G52.9 Cranial nerve disorder, unspecified
0.111 0.889 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.111 0.889 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.111 0.889 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.111 0.889 0.000
Q07 Other congenital malformations of nervous system
0.111 0.889 0.000
G60 Hereditary and idiopathic neuropathy
0.110 0.889 0.000
M05-M14 Inflammatory polyarthropathies
0.111 0.889 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.111 0.889 0.000
G54.8 Other nerve root and plexus disorders
0.110 0.890 0.000
J01.1 Acute frontal sinusitis
0.110 0.890 0.000
G73.0 Myasthenic syndromes in endocrine diseases
0.110 0.890 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.108 0.890 0.002
L10-L14 Bullous disorders
0.110 0.890 0.000
Q04 Other congenital malformations of brain
0.110 0.890 0.000
Q83 Congenital malformations of breast
0.110 0.890 0.000
Q05 Spina bifida
0.110 0.890 0.000
J06.0 Acute laryngopharyngitis
0.109 0.890 0.000
G72.3 Periodic paralysis
0.109 0.890 0.000
G72.2 Myopathy due to other toxic agents
0.109 0.890 0.000
Q36 Cleft lip
0.109 0.891 0.000
Q75 Other congenital malformations of skull and face bones
0.109 0.891 0.000
G52.2 Disorders of vagus nerve
0.109 0.891 0.000
I84.3 External thrombosed haemorrhoids
0.109 0.891 0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.109 0.891 0.000
J01.8 Other acute sinusitis
0.109 0.891 0.000
G03 Meningitis due to other and unspecified causes
0.109 0.891 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.108 0.891 0.000
G70.2 Congenital and developmental myasthenia
0.108 0.892 0.000
G70.1 Toxic myoneural disorders
0.108 0.892 0.000
I88.1 Chronic lymphadenitis, except mesenteric
0.108 0.892 0.000
L73.9 Follicular disorder, unspecified
0.108 0.892 0.000
Q44.6 Cystic disease of liver
0.108 0.892 0.000
G72.0 Drug-induced myopathy
0.108 0.892 0.000
M65-M68 Disorders of synovium and tendon
0.108 0.892 0.000
G58 Other mononeuropathies
0.107 0.892 0.000
E55.9 Vitamin D deficiency, unspecified
0.107 0.892 0.000
L51 Erythema multiforme
0.107 0.893 0.000
G72.1 Alcoholic myopathy
0.107 0.893 0.000
L50 Urticaria
0.107 0.893 0.000
G54.7 Phantom limb syndrome without pain
0.107 0.893 0.000
G54.3 Thoracic root disorders, not elsewhere classified
0.107 0.893 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.107 0.893 0.000
G52.0 Disorders of olfactory nerve
0.107 0.893 0.000
Q73 Reduction defects of unspecified limb
0.106 0.893 0.000
Q72 Reduction defects of lower limb
0.106 0.893 0.000
Q71 Reduction defects of upper limb
0.106 0.893 0.000
Q69 Polydactyly
0.106 0.893 0.000
Q03 Congenital hydrocephalus
0.106 0.893 0.000
Q53 Undescended testicle
0.106 0.894 0.000
Q21.4 Aortopulmonary septal defect
0.106 0.894 0.000
Q21.2 Atrioventricular septal defect
0.106 0.894 0.000
M05 Seropositive rheumatoid arthritis
0.106 0.894 0.000
G64 Other disorders of peripheral nervous system
0.106 0.894 0.000
Q01 Encephalocele
0.106 0.894 0.000
Q00 Anencephaly and similar malformations
0.106 0.894 0.000
Q02 Microcephaly
0.106 0.894 0.000
L29.2 Pruritus vulvae
0.106 0.894 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.106 0.894 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.106 0.894 0.000
G71.9 Primary disorder of muscle, unspecified
0.105 0.894 0.000
G71.8 Other primary disorders of muscles
0.105 0.894 0.000
G71.2 Congenital myopathies
0.105 0.894 0.000
Q66.3 Other congenital varus deformities of feet
0.105 0.894 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.105 0.895 0.000
G54.5 Neuralgic amyotrophy
0.105 0.895 0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.105 0.895 0.000
Q84 Other congenital malformations of integument
0.105 0.895 0.000
Q81 Epidermolysis bullosa
0.105 0.895 0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified
0.105 0.895 0.000
L73.8 Other specified follicular disorders
0.105 0.895 0.000
L70 Acne
0.105 0.895 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.104 0.895 0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified
0.104 0.896 0.000
G24.5 Blepharospasm
0.104 0.896 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.104 0.896 0.000
J01.0 Acute maxillary sinusitis
0.104 0.896 0.000
Q60.2 Renal agenesis, unspecified
0.104 0.896 0.000
I02 Rheumatic chorea
0.104 0.896 0.000
I01 Rheumatic fever with heart involvement
0.104 0.896 0.000
Q25 Congenital malformations of great arteries
0.104 0.896 0.000
J01.2 Acute ethmoidal sinusitis
0.104 0.896 0.000
G52.7 Disorders of multiple cranial nerves
0.103 0.896 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.103 0.896 0.000
G52.1 Disorders of glossopharyngeal nerve
0.103 0.897 0.000
Q68 Other congenital musculoskeletal deformities
0.103 0.897 0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck
0.103 0.897 0.000
Q90 Down's syndrome
0.103 0.897 0.000
I86.2 Pelvic varices
0.103 0.897 0.000
G40.9 Epilepsy, unspecified
0.103 0.897 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.102 0.898 0.000
Q60.0 Renal agenesis, unilateral
0.102 0.898 0.000
Q85.0 Neurofibromatosis (nonmalignant)
0.102 0.898 0.000
Q45.8 Other specified congenital malformations of digestive system
0.102 0.898 0.000
Q66.8 Other congenital deformities of feet
0.102 0.898 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.102 0.898 0.000
G71.1 Myotonic disorders
0.102 0.898 0.000
Q66.6 Other congenital valgus deformities of feet
0.102 0.898 0.000
Q21.0 Ventricular septal defect
0.102 0.898 0.000
G62.9 Polyneuropathy, unspecified
0.102 0.898 0.000
Q24.4 Congenital subaortic stenosis
0.102 0.898 0.000
J01.3 Acute sphenoidal sinusitis
0.102 0.898 0.000
Q63.8 Other specified congenital malformations of kidney
0.101 0.898 0.000
G73.6 Myopathy in metabolic diseases
0.101 0.899 0.000
G73.5 Myopathy in endocrine diseases
0.101 0.899 0.000
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere
0.101 0.899 0.000
G73.3 Myasthenic syndromes in other diseases classified elsewhere
0.101 0.899 0.000
G73.2 Other myasthenic syndromes in neoplastic disease
0.101 0.899 0.000
G73.1 Eaton-Lambert syndrome
0.101 0.899 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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