TreeWAS – Variant ID: rs4937314

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T40.2 Other opioids	0.036	0.964	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.966	0.034
J38.7 Other diseases of larynx	0.000	0.968	0.032
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.028	0.972	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.000	0.974	0.026
T36-T50 Poisoning by drugs, medicaments and biological substances	0.024	0.976	0.000
J38.4 Oedema of larynx	0.000	0.977	0.023
J38.3 Other diseases of vocal cords	0.000	0.977	0.023
J38.2 Nodules of vocal cords	0.000	0.977	0.022
H55 Nystagmus and other irregular eye movements	0.022	0.978	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.021	0.979	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.021	0.979	0.000
T40.6 Other and unspecified narcotics	0.021	0.979	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.021	0.979	0.000
T40.8 Lysergide [LSD]	0.021	0.979	0.000
T40.7 Cannabis (derivatives)	0.021	0.979	0.000
T40.5 Cocaine	0.021	0.979	0.000
T40.3 Methadone	0.021	0.979	0.000
T40.1 Heroin	0.021	0.979	0.000
T40.0 Opium	0.021	0.979	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.020	0.980	0.000
J38.6 Stenosis of larynx	0.000	0.980	0.019
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.019	0.981	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.019	0.981	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.019	0.981	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.019	0.981	0.000
T40.4 Other synthetic narcotics	0.018	0.981	0.000
H55-H59 Other disorders of eye and adnexa	0.018	0.982	0.000
H57.8 Other specified disorders of eye and adnexa	0.018	0.982	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.018	0.982	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.018	0.982	0.000
J38.0 Paralysis of vocal cords and larynx	0.000	0.982	0.018
H57 Other disorders of eye and adnexa	0.018	0.982	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.017	0.982	0.000
T39.0 Salicylates	0.017	0.983	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.017	0.983	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.017	0.983	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.017	0.983	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.017	0.983	0.000
S02.2 Fracture of nasal bones	0.000	0.983	0.017
T47.1 Other antacids and anti-gastric-secretion drugs	0.017	0.983	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.016	0.984	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.016	0.984	0.000
T42.1 Iminostilbenes	0.016	0.984	0.000
H43.1 Vitreous haemorrhage	0.016	0.984	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.016	0.984	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.016	0.984	0.000
T42.0 Hydantoin derivatives	0.015	0.984	0.000
T46.1 Calcium-channel blockers	0.015	0.984	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.015	0.984	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.015	0.984	0.000
T42.3 Barbiturates	0.015	0.984	0.000
T42.2 Succinimides and oxazolidinediones	0.015	0.984	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.015	0.985	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.015	0.985	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.015	0.985	0.000
T46.7 Peripheral vasodilators	0.015	0.985	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.015	0.985	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.015	0.985	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.015	0.985	0.000
J38.5 Laryngeal spasm	0.000	0.985	0.015
T48.6 Antiasthmatics, not elsewhere classified	0.015	0.985	0.000
H49.1 Fourth [trochlear] nerve palsy	0.015	0.985	0.000
T42.4 Benzodiazepines	0.015	0.985	0.000
H43 Disorders of vitreous body	0.015	0.985	0.000
T36 Poisoning by systemic antibiotics	0.015	0.985	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.014	0.985	0.000
J38.1 Polyp of vocal cord and larynx	0.000	0.985	0.014
H49 Paralytic strabismus	0.014	0.986	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.014	0.986	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.014	0.986	0.000
T47.7 Emetics	0.014	0.986	0.000
T47.6 Antidiarrhoeal drugs	0.014	0.986	0.000
T47.5 Digestants	0.014	0.986	0.000
T47.4 Other laxatives	0.014	0.986	0.000
T47.3 Saline and osmotic laxatives	0.014	0.986	0.000
T47.2 Stimulant laxatives	0.014	0.986	0.000
T47.0 Histamine H(2)-receptor antagonists	0.014	0.986	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.014	0.986	0.000
T43.9 Psychotropic drug, unspecified	0.014	0.986	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.014	0.986	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.014	0.986	0.000
H57.0 Anomalies of pupillary function	0.014	0.986	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.014	0.986	0.000
T43.6 Psychostimulants with abuse potential	0.014	0.986	0.000
T39.4 Antirheumatics, not elsewhere classified	0.014	0.986	0.000
T39.2 Pyrazolone derivatives	0.014	0.986	0.000
H43-H45 Disorders of vitreous body and globe	0.014	0.986	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.013	0.986	0.000
T48.5 Anti-common-cold drugs	0.013	0.986	0.000
T48.4 Expectorants	0.013	0.986	0.000
T48.3 Antitussives	0.013	0.986	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.013	0.986	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.013	0.986	0.000
T48.0 Oxytocic drugs	0.013	0.986	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.014	0.986	0.000
H43.8 Other disorders of vitreous body	0.013	0.987	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.013	0.987	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.013	0.987	0.000
T39.1 4-Aminophenol derivatives	0.013	0.987	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.013	0.987	0.000
Z98.1 Arthrodesis status	0.013	0.987	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.013	0.987	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.012	0.987	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.012	0.987	0.000
T37.5 Antiviral drugs	0.012	0.987	0.000
T37.4 Anthelminthics	0.012	0.987	0.000
T37.3 Other antiprotozoal drugs	0.012	0.987	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.012	0.987	0.000
T37.1 Antimycobacterial drugs	0.012	0.987	0.000
T37.0 Sulphonamides	0.012	0.987	0.000
T41.5 Therapeutic gases	0.012	0.987	0.000
T41.4 Anaesthetic, unspecified	0.012	0.987	0.000
T41.3 Local anaesthetics	0.012	0.987	0.000
T41.2 Other and unspecified general anaesthetics	0.012	0.987	0.000
T41.1 Intravenous anaesthetics	0.012	0.987	0.000
T41.0 Inhaled anaesthetics	0.012	0.987	0.000
T49.9 Topical agent, unspecified	0.012	0.987	0.000
T49.8 Other topical agents	0.012	0.987	0.000
T49.7 Dental drugs, topically applied	0.012	0.987	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.012	0.987	0.000
T49.5 Ophthalmological drugs and preparations	0.012	0.987	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.012	0.987	0.000
T49.3 Emollients, demulcents and protectants	0.012	0.987	0.000
T49.2 Local astringents and local detergents	0.012	0.987	0.000
T49.1 Antipruritics	0.012	0.987	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.012	0.987	0.000
T38.9 Other and unspecified hormone antagonists	0.012	0.987	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.012	0.987	0.000
T38.7 Androgens and anabolic congeners	0.012	0.987	0.000
T38.5 Other oestrogens and progestogens	0.012	0.987	0.000
T38.4 Oral contraceptives	0.012	0.987	0.000
T38.2 Antithyroid drugs	0.012	0.987	0.000
T38.0 Glucocorticoids and synthetic analogues	0.012	0.987	0.000
S02.21 Fracture of nasal bones (open)	0.000	0.987	0.012
T38.1 Thyroid hormones and substitutes	0.012	0.988	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.012	0.988	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.012	0.988	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.012	0.988	0.000
T45.2 Vitamins, not elsewhere classified	0.012	0.988	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.012	0.988	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.012	0.988	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.012	0.988	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.012	0.988	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.012	0.988	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.012	0.988	0.000
T44.0 Anticholinesterase agents	0.012	0.988	0.000
H44 Disorders of globe	0.012	0.988	0.000
H49.2 Sixth [abducent] nerve palsy	0.012	0.988	0.000
Chapter VII Diseases of the eye and adnexa	0.012	0.988	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.012	0.988	0.000
T45.8 Other primarily systemic and haematological agents	0.012	0.988	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.012	0.988	0.000
T45.6 Fibrinolysis-affecting drugs	0.012	0.988	0.000
T45.4 Iron and its compounds	0.012	0.988	0.000
T45.3 Enzymes, not elsewhere classified	0.012	0.988	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.011	0.988	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.011	0.989	0.000
H54 Blindness and low vision	0.011	0.989	0.000
H52 Disorders of refraction and accommodation	0.011	0.989	0.000
H54.9 Unspecified visual impairment (binocular)	0.011	0.989	0.000
N92.1 Excessive and frequent menstruation with irregular cycle	0.011	0.989	0.000
H43.9 Disorder of vitreous body, unspecified	0.011	0.989	0.000
H49.0 Third [oculomotor] nerve palsy	0.011	0.989	0.000
H43.0 Vitreous prolapse	0.011	0.989	0.000
H53-H54 Visual disturbances and blindness	0.011	0.989	0.000
T36.9 Systemic antibiotic, unspecified	0.011	0.989	0.000
T36.8 Other systemic antibiotics	0.011	0.989	0.000
T36.7 Antifungal antibiotics, systemically used	0.011	0.989	0.000
T36.6 Rifamycins	0.011	0.989	0.000
T36.5 Aminoglycosides	0.011	0.989	0.000
T36.4 Tetracyclines	0.011	0.989	0.000
T36.3 Macrolides	0.011	0.989	0.000
T36.2 Chloramphenicol group	0.011	0.989	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.011	0.989	0.000
H49.9 Paralytic strabismus, unspecified	0.011	0.989	0.000
H52.3 Anisometropia and aniseikonia	0.011	0.989	0.000
H57.1 Ocular pain	0.011	0.989	0.000
T45.0 Antiallergic and antiemetic drugs	0.011	0.989	0.000
H49.8 Other paralytic strabismus	0.010	0.989	0.000
H49.4 Progressive external ophthalmoplegia	0.010	0.989	0.000
H49.3 Total (external) ophthalmoplegia	0.010	0.989	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.010	0.989	0.000
H54.4 Blindness, one eye	0.010	0.990	0.000
H44.2 Degenerative myopia	0.010	0.990	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.010	0.990	0.000
T50.8 Diagnostic agents	0.010	0.990	0.000
T50.7 Analeptics and opioid receptor antagonists	0.010	0.990	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.010	0.990	0.000
T50.5 Appetite depressants	0.010	0.990	0.000
T50.4 Drugs affecting uric acid metabolism	0.010	0.990	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.010	0.990	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.010	0.990	0.000
T50.1 Loop [high-ceiling] diuretics	0.010	0.990	0.000
T50.0 Mineralocorticoids and their antagonists	0.010	0.990	0.000
H43.2 Crystalline deposits in vitreous body	0.010	0.990	0.000
T43.2 Other and unspecified antidepressants	0.010	0.990	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.010	0.990	0.000
H51 Other disorders of binocular movement	0.010	0.990	0.000
H44.5 Degenerated conditions of globe	0.010	0.990	0.000
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.010	0.990	0.000
H58.1 Visual disturbances in diseases classified elsewhere	0.010	0.990	0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.010	0.990	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.010	0.990	0.000
H44.9 Disorder of globe, unspecified	0.009	0.990	0.000
H44.4 Hypotony of eye	0.009	0.991	0.000
H52.7 Disorder of refraction, unspecified	0.009	0.991	0.000
H58.8 Visual disturbances in diseases classified elsewhere	0.009	0.991	0.000
H10-H13 Disorders of conjunctiva	0.009	0.991	0.000
T45.5 Anticoagulants	0.009	0.991	0.000
H44.1 Other endophthalmitis	0.009	0.991	0.000
H54.7 Unspecified visual loss	0.009	0.991	0.000
H54.1 Blindness, one eye, low vision, other eye	0.009	0.991	0.000
Q05.9 Spina bifida, unspecified	0.009	0.991	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.009	0.991	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.009	0.991	0.000
H44.8 Other disorders of globe	0.009	0.991	0.000
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.009	0.991	0.000
H44.6 Retained (old) intraocular foreign body, magnetic	0.009	0.991	0.000
H44.3 Other degenerative disorders of globe	0.009	0.991	0.000
H54.2 Low vision, both eyes	0.009	0.991	0.000
H43.3 Other vitreous opacities	0.009	0.991	0.000
H11 Other disorders of conjunctiva	0.009	0.991	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.008	0.991	0.000
H59.0 Vitreous syndrome following cataract surgery	0.008	0.991	0.000
H54.6 Unqualified visual loss, one eye	0.008	0.992	0.000
H54.5 Low vision, one eye	0.008	0.992	0.000
H54.3 Unqualified visual loss, both eyes	0.008	0.992	0.000
H52.6 Other disorders of refraction	0.008	0.992	0.000
H52.5 Disorders of accommodation	0.008	0.992	0.000
H52.4 Presbyopia	0.008	0.992	0.000
T36.0 Penicillins	0.008	0.992	0.000
H52.2 Astigmatism	0.008	0.992	0.000
H52.0 Hypermetropia	0.008	0.992	0.000
J32.2 Chronic ethmoidal sinusitis	0.000	0.992	0.008
J32 Chronic sinusitis	0.000	0.992	0.008
H11.4 Other conjunctival vascular disorders and cysts	0.008	0.992	0.000
J35.1 Hypertrophy of tonsils	0.000	0.992	0.008
H45.8 Other disorders of vitreous body and globe in diseases classified elsewhere	0.007	0.992	0.000
H45.1 Endophthalmitis in diseases classified elsewhere	0.007	0.992	0.000
H45.0 Vitreous haemorrhage in diseases classified elsewhere	0.007	0.992	0.000
H51.2 Internuclear ophthalmoplegia	0.007	0.992	0.000
H50 Other strabismus	0.008	0.992	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.007	0.993	0.000
J30-J39 Other diseases of upper respiratory tract	0.000	0.993	0.007
H51.9 Disorder of binocular movement, unspecified	0.007	0.993	0.000
H51.8 Other specified disorders of binocular movement	0.007	0.993	0.000
H51.1 Convergence insufficiency and excess	0.007	0.993	0.000
H51.0 Palsy of conjugate gaze	0.007	0.993	0.000
J32.8 Other chronic sinusitis	0.000	0.993	0.007
Q05 Spina bifida	0.007	0.993	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.007	0.993	0.000
H47.3 Other disorders of optic disk	0.007	0.993	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.007	0.993	0.000
J35 Chronic diseases of tonsils and adenoids	0.000	0.993	0.007
E05.9 Thyrotoxicosis, unspecified	0.000	0.993	0.007
J32.0 Chronic maxillary sinusitis	0.000	0.993	0.007
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.007	0.993	0.000
H11.0 Pterygium	0.007	0.993	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.006	0.993	0.000
H11.3 Conjunctival haemorrhage	0.007	0.993	0.000
H50.5 Heterophoria	0.007	0.993	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.006	0.994	0.000
H44.0 Purulent endophthalmitis	0.006	0.994	0.000
H11.8 Other specified disorders of conjunctiva	0.006	0.994	0.000
H11.2 Conjunctival scars	0.006	0.994	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.006	0.994	0.000
H50.2 Vertical strabismus	0.006	0.994	0.000
H52.1 Myopia	0.006	0.994	0.000
H11.9 Disorder of conjunctiva, unspecified	0.006	0.994	0.000
H11.1 Conjunctival degenerations and deposits	0.006	0.994	0.000
J32.4 Chronic pansinusitis	0.000	0.994	0.006
J32.1 Chronic frontal sinusitis	0.000	0.994	0.006
Q00-Q07 Congenital malformations of the nervous system	0.006	0.994	0.000
H50.8 Other specified strabismus	0.006	0.994	0.000
N28.8 Other specified disorders of kidney and ureter	0.000	0.994	0.006
J32.3 Chronic sphenoidal sinusitis	0.000	0.994	0.006
H46 Optic neuritis	0.006	0.994	0.000
H54.0 Blindness, both eyes	0.006	0.994	0.000
J37 Chronic laryngitis and laryngotracheitis	0.000	0.994	0.006
Z71.3 Dietary counselling and surveillance	0.000	0.994	0.006
H47.1 Papilloedema, unspecified	0.006	0.994	0.000
H50.6 Mechanical strabismus	0.006	0.994	0.000
H50.3 Intermittent heterotropia	0.006	0.994	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.000	0.994	0.006
H47.7 Disorder of visual pathways, unspecified	0.005	0.994	0.000
H47.6 Disorders of visual cortex	0.005	0.994	0.000
H47.5 Disorders of other visual pathways	0.005	0.994	0.000
H47.4 Disorders of optic chiasm	0.005	0.994	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.005	0.995	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.005	0.995	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.005	0.995	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.005	0.995	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.005	0.995	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.005	0.995	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.005	0.995	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.005	0.995	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.005	0.995	0.000
H10 Conjunctivitis	0.005	0.995	0.000
Z48.9 Surgical follow-up care, unspecified	0.005	0.995	0.000
J35.2 Hypertrophy of adenoids	0.000	0.995	0.005
H40-H42 Glaucoma	0.005	0.995	0.000
H13.8 Other disorders of conjunctiva in diseases classified elsewhere	0.005	0.995	0.000
H13.3 Ocular pemphigoid	0.005	0.995	0.000
H13.2 Conjunctivitis in other diseases classified elsewhere	0.005	0.995	0.000
H13.1 Conjunctivitis in infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
H13.0 Filarial infection of conjunctiva	0.005	0.995	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.005	0.995	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.005	0.995	0.000
H50.4 Other and unspecified heterotropia	0.005	0.995	0.000
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.000	0.995	0.005
H53 Visual disturbances	0.005	0.995	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.005	0.995	0.000
Q80-Q89 Other congenital malformations	0.005	0.995	0.000
H47.2 Optic atrophy	0.005	0.995	0.000
H48.8 Other disorders of optic nerve and visual pathways in diseases classified elsewhere	0.005	0.995	0.000
H48.1 Retrobulbar neuritis in diseases classified elsewhere	0.005	0.995	0.000
H48.0 Optic atrophy in diseases classified elsewhere	0.005	0.995	0.000
S02 Fracture of skull and facial bones	0.000	0.995	0.005
I24.8 Other forms of acute ischaemic heart disease	0.005	0.995	0.000
Q87.4 Marfan's syndrome	0.005	0.995	0.000
M07.3 Other psoriatic arthropathies	0.005	0.995	0.000
K31.7 Polyp of stomach and duodenum	0.000	0.995	0.005
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.000	0.995	0.005
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.005	0.995	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.005	0.995	0.000
J30 Vasomotor and allergic rhinitis	0.000	0.995	0.005
H53.0 Amblyopia ex anopsia	0.005	0.995	0.000
J31.0 Chronic rhinitis	0.000	0.995	0.005
J35.0 Chronic tonsillitis	0.000	0.995	0.005
J37.0 Chronic laryngitis	0.000	0.995	0.005
H50.1 Divergent concomitant strabismus	0.005	0.995	0.000
Q06 Other congenital malformations of spinal cord	0.004	0.995	0.000
Q04 Other congenital malformations of brain	0.004	0.995	0.000
Q03 Congenital hydrocephalus	0.004	0.995	0.000
Q01 Encephalocele	0.004	0.995	0.000
Q00 Anencephaly and similar malformations	0.004	0.995	0.000
Q02 Microcephaly	0.004	0.995	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.000	0.995	0.005
J36 Peritonsillar abscess	0.000	0.995	0.005
H47.0 Disorders of optic nerve, not elsewhere classified	0.004	0.995	0.000
J39 Other diseases of upper respiratory tract	0.000	0.996	0.004
J37.1 Chronic laryngotracheitis	0.000	0.996	0.004
Q07 Other congenital malformations of nervous system	0.004	0.996	0.000
Q76 Congenital malformations of spine and bony thorax	0.004	0.996	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.004	0.996	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.004	0.996	0.000
Q90 Down's syndrome	0.004	0.996	0.000
S02.7 Multiple fractures involving skull and facial bones	0.000	0.996	0.004
J31.1 Chronic nasopharyngitis	0.000	0.996	0.004
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.004	0.996	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.004	0.996	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.004	0.996	0.000
Q96 Turner's syndrome	0.004	0.996	0.000
S02.5 Fracture of tooth	0.000	0.996	0.004
H17 Corneal scars and opacities	0.004	0.996	0.000
H10.8 Other conjunctivitis	0.004	0.996	0.000
H10.5 Blepharoconjunctivitis	0.004	0.996	0.000
H10.3 Acute conjunctivitis, unspecified	0.004	0.996	0.000
H10.2 Other acute conjunctivitis	0.004	0.996	0.000
H10.1 Acute atopic conjunctivitis	0.004	0.996	0.000
H10.0 Mucopurulent conjunctivitis	0.004	0.996	0.000
H50.9 Strabismus, unspecified	0.004	0.996	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.004	0.996	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.996	0.004
Q89 Other congenital malformations, not elsewhere classified	0.004	0.996	0.000
Q10.0 Congenital ptosis	0.004	0.996	0.000
H21 Other disorders of iris and ciliary body	0.004	0.996	0.000
Y52 Agents primarily affecting the cardiovascular system	0.004	0.996	0.000
S02.8 Fractures of other skull and facial bones	0.000	0.996	0.004
H42 Glaucoma in diseases classified elsewhere	0.004	0.996	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.004	0.996	0.000
H53.2 Diplopia	0.004	0.996	0.000
Q90.9 Down's syndrome, unspecified	0.004	0.996	0.000
D24 Benign neoplasm of breast	0.004	0.996	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.004	0.996	0.000
H15 Disorders of sclera	0.004	0.996	0.000
Q50-Q56 Congenital malformations of genital organs	0.004	0.996	0.000
Q35-Q37 Cleft lip and cleft palate	0.004	0.996	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.004	0.996	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.004	0.996	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.004	0.996	0.000
H53.6 Night blindness	0.004	0.996	0.000
H53.5 Colour vision deficiencies	0.004	0.996	0.000
H53.3 Other disorders of binocular vision	0.004	0.996	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.004	0.996	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.004	0.996	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.004	0.996	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.004	0.996	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.004	0.996	0.000
Q84 Other congenital malformations of integument	0.004	0.996	0.000
Q81 Epidermolysis bullosa	0.004	0.996	0.000
Q80 Congenital ichthyosis	0.004	0.996	0.000
J30.3 Other allergic rhinitis	0.000	0.996	0.004
Q82 Other congenital malformations of skin	0.004	0.996	0.000
Q74 Other congenital malformations of limb(s)	0.004	0.996	0.000
Q66 Congenital deformities of feet	0.004	0.996	0.000
Q85 Phakomatoses, not elsewhere classified	0.004	0.996	0.000
Q76.1 Klippel-Feil syndrome	0.004	0.996	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.000	0.996	0.004
Q83 Congenital malformations of breast	0.004	0.996	0.000
Y57 Other and unspecified drugs and medicaments	0.004	0.996	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.004	0.996	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.004	0.996	0.000
Q76.0 Spina bifida occulta	0.004	0.996	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.004	0.996	0.000
M07.38 Other psoriatic arthropathies (Other)	0.004	0.996	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.004	0.996	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.004	0.996	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.004	0.996	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.004	0.996	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.004	0.996	0.000
J31.2 Chronic pharyngitis	0.000	0.996	0.004
H18 Other disorders of cornea	0.004	0.996	0.000
H18.6 Keratoconus	0.004	0.996	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.004	0.996	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.004	0.996	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.004	0.996	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.004	0.996	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.004	0.996	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.004	0.996	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.004	0.996	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.004	0.996	0.000
Q96.9 Turner's syndrome, unspecified	0.004	0.996	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.004	0.996	0.000
Q75 Other congenital malformations of skull and face bones	0.004	0.996	0.000
Q73 Reduction defects of unspecified limb	0.004	0.996	0.000
Q72 Reduction defects of lower limb	0.004	0.996	0.000
Q71 Reduction defects of upper limb	0.004	0.996	0.000
Q70 Syndactyly	0.004	0.996	0.000
Q69 Polydactyly	0.004	0.996	0.000
Q68 Other congenital musculoskeletal deformities	0.004	0.996	0.000
Q60-Q64 Congenital malformations of the urinary system	0.004	0.996	0.000
J30.2 Other seasonal allergic rhinitis	0.000	0.996	0.004
J30.0 Vasomotor rhinitis	0.000	0.996	0.004
Y57.8 Other drugs and medicaments	0.004	0.996	0.000
Q17 Other congenital malformations of ear	0.003	0.996	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.004	0.996	0.000
H53.1 Subjective visual disturbances	0.004	0.996	0.000
J39.8 Other specified diseases of upper respiratory tract	0.000	0.996	0.004
S02.3 Fracture of orbital floor	0.000	0.996	0.004
S02.0 Fracture of vault of skull	0.000	0.996	0.004
S02.50 Fracture of tooth (closed)	0.000	0.996	0.004
H10.4 Chronic conjunctivitis	0.003	0.996	0.000
J39.0 Retropharyngeal and parapharyngeal abscess	0.000	0.996	0.004
J92.0 Pleural plaque with presence of asbestos	0.000	0.996	0.004
Y42.5 Other oestrogens and progestogens	0.004	0.996	0.000
X41.9 Unspecified place	0.004	0.996	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.996	0.000
Q00.2 Iniencephaly	0.003	0.996	0.000
Q00.1 Craniorachischisis	0.003	0.996	0.000
Q00.0 Anencephaly	0.003	0.996	0.000
Q01.9 Encephalocele, unspecified	0.003	0.996	0.000
Q01.8 Encephalocele of other sites	0.003	0.996	0.000
Q01.2 Occipital encephalocele	0.003	0.996	0.000
Q01.1 Nasofrontal encephalocele	0.003	0.996	0.000
Q01.0 Frontal encephalocele	0.003	0.996	0.000
Q03.9 Congenital hydrocephalus, unspecified	0.003	0.996	0.000
Q03.8 Other congenital hydrocephalus	0.003	0.996	0.000
Q03.1 Atresia of foramina of Magendie and Luschka	0.003	0.996	0.000
Q03.0 Malformations of aqueduct of Sylvius	0.003	0.996	0.000
Q04.9 Congenital malformation of brain, unspecified	0.003	0.996	0.000
Q04.8 Other specified congenital malformations of brain	0.003	0.996	0.000
Q04.6 Congenital cerebral cysts	0.003	0.996	0.000
Q04.5 Megalencephaly	0.003	0.996	0.000
Q04.4 Septo-optic dysplasia	0.003	0.996	0.000
Q04.3 Other reduction deformities of brain	0.003	0.996	0.000
Q04.2 Holoprosencephaly	0.003	0.996	0.000
Q04.1 Arhinencephaly	0.003	0.996	0.000
Q04.0 Congenital malformations of corpus callosum	0.003	0.996	0.000
Q06.9 Congenital malformation of spinal cord, unspecified	0.003	0.996	0.000
Q06.8 Other specified congenital malformations of spinal cord	0.003	0.996	0.000
Q06.4 Hydromyelia	0.003	0.996	0.000
Q06.3 Other congenital cauda equina malformations	0.003	0.996	0.000
Q06.2 Diastematomyelia	0.003	0.996	0.000
Q06.1 Hypoplasia and dysplasia of spinal cord	0.003	0.996	0.000
Q06.0 Amyelia	0.003	0.996	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
S02.1 Fracture of base of skull	0.000	0.996	0.003
Q78 Other osteochondrodysplasias	0.003	0.996	0.000
Y44 Agents primarily affecting blood constituents	0.004	0.996	0.000
Q65 Congenital deformities of hip	0.003	0.996	0.000
H21.8 Other specified disorders of iris and ciliary body	0.003	0.996	0.000
J39.9 Disease of upper respiratory tract, unspecified	0.000	0.996	0.003
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.003	0.996	0.000
D12.2 Ascending colon	0.003	0.997	0.000
H53.8 Other visual disturbances	0.003	0.997	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.003	0.997	0.000
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified	0.000	0.997	0.003
J39.1 Other abscess of pharynx	0.000	0.997	0.003
Q07.9 Congenital malformation of nervous system, unspecified	0.003	0.997	0.000
Q07.8 Other specified congenital malformations of nervous system	0.003	0.997	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.003	0.997	0.000
Q76.8 Other congenital malformations of bony thorax	0.003	0.997	0.000
Q76.7 Congenital malformation of sternum	0.003	0.997	0.000
Q76.6 Other congenital malformations of ribs	0.003	0.997	0.000
Q76.5 Cervical rib	0.003	0.997	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.003	0.997	0.000
Q76.2 Congenital spondylolisthesis	0.003	0.997	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations