TreeWAS – Variant ID: rs4948088

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K83.8 Other specified diseases of biliary tract	0.020	0.980	0.000
K83 Other diseases of biliary tract	0.017	0.983	0.000
K83.0 Cholangitis	0.016	0.984	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.014	0.986	0.000
I69 Sequelae of cerebrovascular disease	0.013	0.987	0.000
I69.3 Sequelae of cerebral infarction	0.013	0.987	0.000
K83.1 Obstruction of bile duct	0.013	0.987	0.000
G56.0 Carpal tunnel syndrome	0.013	0.987	0.000
K83.3 Fistula of bile duct	0.013	0.987	0.000
K83.2 Perforation of bile duct	0.012	0.987	0.000
K83.4 Spasm of sphincter of Oddi	0.012	0.988	0.000
K83.5 Biliary cyst	0.012	0.988	0.000
K83.9 Disease of biliary tract, unspecified	0.011	0.988	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.011	0.989	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.010	0.990	0.000
E10.9 Without complications	0.010	0.990	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.010	0.990	0.000
G56 Mononeuropathies of upper limb	0.010	0.990	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.009	0.991	0.000
H53.0 Amblyopia ex anopsia	0.000	0.991	0.009
G25 Other extrapyramidal and movement disorders	0.009	0.991	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.008	0.991	0.000
G20-G26 Extrapyramidal and movement disorders	0.008	0.992	0.000
I60-I69 Cerebrovascular diseases	0.008	0.992	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.008	0.992	0.000
O72.1 Other immediate postpartum haemorrhage	0.008	0.992	0.000
O60-O75 Complications of labour and delivery	0.008	0.992	0.000
O72 Postpartum haemorrhage	0.008	0.992	0.000
I61 Intracerebral haemorrhage	0.008	0.992	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.008	0.992	0.000
O70 Perineal laceration during delivery	0.008	0.992	0.000
G25.3 Myoclonus	0.008	0.992	0.000
O70.0 First degree perineal laceration during delivery	0.008	0.992	0.000
G51 Facial nerve disorders	0.008	0.992	0.000
G56.8 Other mononeuropathies of upper limb	0.008	0.992	0.000
Chapter VI Diseases of the nervous system	0.008	0.992	0.000
G56.3 Lesion of radial nerve	0.008	0.992	0.000
N95.2 Postmenopausal atrophic vaginitis	0.000	0.992	0.008
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.007	0.993	0.000
G20 Parkinson's disease	0.007	0.993	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.007	0.993	0.000
G81.9 Hemiplegia, unspecified	0.007	0.993	0.000
G51.0 Bell's palsy	0.007	0.993	0.000
G91.9 Hydrocephalus, unspecified	0.007	0.993	0.000
I60 Subarachnoid haemorrhage	0.007	0.993	0.000
G56.9 Mononeuropathy of upper limb, unspecified	0.007	0.993	0.000
G56.1 Other lesions of median nerve	0.007	0.993	0.000
G90-G99 Other disorders of the nervous system	0.007	0.993	0.000
G54 Nerve root and plexus disorders	0.007	0.993	0.000
G56.4 Causalgia	0.007	0.993	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.007	0.993	0.000
G81 Hemiplegia	0.007	0.993	0.000
I67.1 Cerebral aneurysm, nonruptured	0.007	0.993	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.007	0.993	0.000
G52 Disorders of other cranial nerves	0.007	0.993	0.000
G25.1 Drug-induced tremor	0.007	0.993	0.000
O73 Retained placenta and membranes, without haemorrhage	0.007	0.993	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.007	0.993	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.007	0.993	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.007	0.993	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.007	0.993	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.007	0.993	0.000
G91 Hydrocephalus	0.007	0.993	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.007	0.993	0.000
G25.0 Essential tremor	0.007	0.993	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.007	0.993	0.000
O70.9 Perineal laceration during delivery, unspecified	0.007	0.993	0.000
I62 Other nontraumatic intracranial haemorrhage	0.007	0.993	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.007	0.993	0.000
G25.4 Drug-induced chorea	0.007	0.993	0.000
G25.2 Other specified forms of tremor	0.007	0.993	0.000
I67 Other cerebrovascular diseases	0.007	0.993	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.007	0.993	0.000
G54.0 Brachial plexus disorders	0.007	0.993	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.006	0.993	0.000
I61.8 Other intracerebral haemorrhage	0.006	0.993	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.007	0.993	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.006	0.993	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.006	0.993	0.000
G25.5 Other chorea	0.006	0.994	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.006	0.994	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.006	0.994	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.006	0.994	0.000
O61 Failed induction of labour	0.006	0.994	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.006	0.994	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.006	0.994	0.000
G22 Parkinsonism in diseases classified elsewhere	0.006	0.994	0.000
O72.0 Third-stage haemorrhage	0.006	0.994	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.006	0.994	0.000
G21 Secondary Parkinsonism	0.006	0.994	0.000
O69.8 Labour and delivery complicated by other cord complications	0.006	0.994	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.006	0.994	0.000
O60 Preterm delivery	0.006	0.994	0.000
O72.3 Postpartum coagulation defects	0.006	0.994	0.000
G51.9 Disorder of facial nerve, unspecified	0.006	0.994	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.006	0.994	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.006	0.994	0.000
H53 Visual disturbances	0.000	0.994	0.006
O71 Other obstetric trauma	0.006	0.994	0.000
O63 Long labour	0.006	0.994	0.000
G70-G73 Diseases of myoneural junction and muscle	0.006	0.994	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.006	0.994	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.006	0.994	0.000
G23 Other degenerative diseases of basal ganglia	0.006	0.994	0.000
G51.3 Clonic hemifacial spasm	0.006	0.994	0.000
O62 Abnormalities of forces of labour	0.006	0.994	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.006	0.994	0.000
O74 Complications of anaesthesia during labour and delivery	0.006	0.994	0.000
G58 Other mononeuropathies	0.006	0.994	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.006	0.994	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.006	0.994	0.000
O69.3 Labour and delivery complicated by short cord	0.006	0.994	0.000
G12 Spinal muscular atrophy and related syndromes	0.006	0.994	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.006	0.994	0.000
O70.3 Fourth degree perineal laceration during delivery	0.006	0.994	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.006	0.994	0.000
G53 Cranial nerve disorders in diseases classified elsewhere	0.006	0.994	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.006	0.994	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.006	0.994	0.000
G51.4 Facial myokymia	0.006	0.994	0.000
G51.2 Melkersson's syndrome	0.006	0.994	0.000
G51.1 Geniculate ganglionitis	0.006	0.994	0.000
G51.8 Other disorders of facial nerve	0.006	0.994	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.006	0.994	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.006	0.994	0.000
O73.0 Retained placenta, without haemorrhage	0.006	0.994	0.000
W19.2 School, other institution and public administrative area	0.000	0.994	0.006
I67.9 Cerebrovascular disease, unspecified	0.006	0.994	0.000
G54.8 Other nerve root and plexus disorders	0.006	0.994	0.000
O70.2 Third degree perineal laceration during delivery	0.006	0.994	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.006	0.994	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.005	0.994	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.006	0.994	0.000
G81.1 Spastic hemiplegia	0.005	0.994	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.005	0.994	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.005	0.994	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.005	0.994	0.000
G50 Disorders of trigeminal nerve	0.005	0.994	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.006	0.994	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.005	0.994	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.006	0.994	0.000
G52.3 Disorders of hypoglossal nerve	0.005	0.994	0.000
G54.1 Lumbosacral plexus disorders	0.005	0.994	0.000
H53.9 Visual disturbance, unspecified	0.000	0.994	0.006
G54.5 Neuralgic amyotrophy	0.005	0.994	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.005	0.994	0.000
G24 Dystonia	0.005	0.994	0.000
G61 Inflammatory polyneuropathy	0.005	0.994	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.005	0.994	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.005	0.994	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.005	0.994	0.000
G14 Postpolio syndrome	0.005	0.994	0.000
G52.8 Disorders of other specified cranial nerves	0.005	0.995	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.005	0.995	0.000
G92 Toxic encephalopathy	0.005	0.995	0.000
G11 Hereditary ataxia	0.005	0.995	0.000
O66 Other obstructed labour	0.005	0.995	0.000
G52.1 Disorders of glossopharyngeal nerve	0.005	0.995	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.005	0.995	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.005	0.995	0.000
G93 Other disorders of brain	0.005	0.995	0.000
G52.2 Disorders of vagus nerve	0.005	0.995	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.005	0.995	0.000
G52.7 Disorders of multiple cranial nerves	0.005	0.995	0.000
G91.1 Obstructive hydrocephalus	0.005	0.995	0.000
O70.1 Second degree perineal laceration during delivery	0.005	0.995	0.000
G12.2 Motor neuron disease	0.005	0.995	0.000
G54.7 Phantom limb syndrome without pain	0.005	0.995	0.000
G54.3 Thoracic root disorders, not elsewhere classified	0.005	0.995	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.005	0.995	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.005	0.995	0.000
G81.0 Flaccid hemiplegia	0.005	0.995	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.005	0.995	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.005	0.995	0.000
G80 Infantile cerebral palsy	0.005	0.995	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.005	0.995	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.005	0.995	0.000
G10 Huntington's disease	0.005	0.995	0.000
G52.0 Disorders of olfactory nerve	0.005	0.995	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.005	0.995	0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere	0.005	0.995	0.000
G52.9 Cranial nerve disorder, unspecified	0.005	0.995	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.005	0.995	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.005	0.995	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.005	0.995	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.005	0.995	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.005	0.995	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.005	0.995	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.005	0.995	0.000
O65.0 Obstructed labour due to deformed pelvis	0.005	0.995	0.000
G91.8 Other hydrocephalus	0.005	0.995	0.000
G54.2 Cervical root disorders, not elsewhere classified	0.005	0.995	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.005	0.995	0.000
I60.8 Other subarachnoid haemorrhage	0.005	0.995	0.000
O61.0 Failed medical induction of labour	0.005	0.995	0.000
O62.0 Primary inadequate contractions	0.005	0.995	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.005	0.995	0.000
O75.0 Maternal distress during labour and delivery	0.005	0.995	0.000
G72 Other myopathies	0.005	0.995	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.005	0.995	0.000
I62.1 Nontraumatic extradural haemorrhage	0.005	0.995	0.000
O63.0 Prolonged first stage (of labour)	0.005	0.995	0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.005	0.995	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.005	0.995	0.000
G83 Other paralytic syndromes	0.005	0.995	0.000
G03 Meningitis due to other and unspecified causes	0.005	0.995	0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.005	0.995	0.000
I67.5 Moyamoya disease	0.005	0.995	0.000
I67.3 Progressive vascular leukoencephalopathy	0.005	0.995	0.000
H54.7 Unspecified visual loss	0.000	0.995	0.005
H53.2 Diplopia	0.000	0.995	0.005
G54.4 Lumbosacral root disorders, not elsewhere classified	0.005	0.995	0.000
O75.4 Other complications of obstetric surgery and procedures	0.005	0.995	0.000
O75.1 Shock during or following labour and delivery	0.005	0.995	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.005	0.995	0.000
G95 Other diseases of spinal cord	0.005	0.995	0.000
I68.0 Cerebral amyloid angiopathy	0.005	0.995	0.000
O67.8 Other intrapartum haemorrhage	0.005	0.995	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.005	0.995	0.000
H53.5 Colour vision deficiencies	0.000	0.995	0.005
G57 Mononeuropathies of lower limb	0.005	0.995	0.000
G54.6 Phantom limb syndrome with pain	0.005	0.995	0.000
G61.0 Guillain-Barre syndrome	0.005	0.995	0.000
O71.5 Other obstetric injury to pelvic organs	0.005	0.995	0.000
O75.9 Complication of labour and delivery, unspecified	0.005	0.995	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
H54 Blindness and low vision	0.000	0.995	0.005
G21.4 Vascular parkinsonism	0.005	0.995	0.000
O61.9 Failed induction of labour, unspecified	0.005	0.995	0.000
O71.4 Obstetric high vaginal laceration alone	0.005	0.995	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.005	0.995	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.005	0.995	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.005	0.995	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
G90 Disorders of autonomic nervous system	0.005	0.995	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.005	0.995	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.005	0.995	0.000
O61.8 Other failed induction of labour	0.005	0.995	0.000
O71.3 Obstetric laceration of cervix	0.005	0.995	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.005	0.995	0.000
G30-G32 Other degenerative diseases of the nervous system	0.005	0.995	0.000
G93.4 Encephalopathy, unspecified	0.005	0.995	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.005	0.995	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.005	0.995	0.000
G71 Primary disorders of muscles	0.005	0.995	0.000
G00 Bacterial meningitis, not elsewhere classified	0.005	0.995	0.000
G21.8 Other secondary Parkinsonism	0.005	0.995	0.000
G21.3 Postencephalitic Parkinsonism	0.005	0.995	0.000
G21.2 Secondary Parkinsonism due to other external agents	0.005	0.995	0.000
I67.4 Hypertensive encephalopathy	0.004	0.995	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.005	0.995	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.005	0.995	0.000
W19 Unspecified fall	0.000	0.995	0.005
C67.9 Bladder, unspecified	0.005	0.995	0.000
G21.1 Other drug-induced secondary Parkinsonism	0.005	0.995	0.000
G58.8 Other specified mononeuropathies	0.005	0.995	0.000
O75.3 Other infection during labour	0.005	0.995	0.000
W19.4 Street and highway	0.000	0.995	0.005
G56.2 Lesion of ulnar nerve	0.005	0.995	0.000
G91.0 Communicating hydrocephalus	0.005	0.995	0.000
O60.3 Preterm delivery without spontaneous labour	0.005	0.995	0.000
O60.2 Preterm spontaneous labour with term delivery	0.005	0.995	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.005	0.995	0.000
O60.0 Preterm labour without delivery	0.005	0.995	0.000
I63 Cerebral infarction	0.005	0.995	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.005	0.995	0.000
O71.9 Obstetric trauma, unspecified	0.005	0.995	0.000
G21.9 Secondary Parkinsonism, unspecified	0.004	0.995	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.005	0.995	0.000
G21.0 Malignant neuroleptic syndrome	0.004	0.995	0.000
H53.6 Night blindness	0.000	0.995	0.005
O63.2 Delayed delivery of second twin, triplet, etc.	0.005	0.995	0.000
O71.2 Postpartum inversion of uterus	0.004	0.995	0.000
O71.1 Rupture of uterus during labour	0.004	0.995	0.000
O71.0 Rupture of uterus before onset of labour	0.004	0.995	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.004	0.995	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.004	0.995	0.000
G23.8 Other specified degenerative diseases of basal ganglia	0.004	0.995	0.000
G59.8 Other mononeuropathies in diseases classified elsewhere	0.004	0.995	0.000
H54.4 Blindness, one eye	0.000	0.995	0.005
O62.9 Abnormality of forces of labour, unspecified	0.004	0.995	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.004	0.995	0.000
G23.3 Multiple system atrophy, cerebellar type	0.004	0.995	0.000
G23.2 Striatonigral degeneration	0.004	0.995	0.000
G23.0 Hallervorden-Spatz disease	0.004	0.995	0.000
G93.0 Cerebral cysts	0.005	0.995	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.005	0.995	0.000
G58.0 Intercostal neuropathy	0.004	0.995	0.000
O63.9 Long labour, unspecified	0.005	0.995	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.004	0.995	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.004	0.995	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.004	0.995	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.004	0.995	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.004	0.995	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.004	0.995	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.004	0.995	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.004	0.995	0.000
G91.2 Normal-pressure hydrocephalus	0.004	0.995	0.000
G94.2 Hydrocephalus in other diseases classified elsewhere	0.004	0.995	0.000
H53-H54 Visual disturbances and blindness	0.000	0.995	0.005
G12.9 Spinal muscular atrophy, unspecified	0.004	0.995	0.000
G12.8 Other spinal muscular atrophies and related syndromes	0.004	0.995	0.000
G12.1 Other inherited spinal muscular atrophy	0.004	0.995	0.000
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]	0.004	0.995	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.004	0.995	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.004	0.995	0.000
G96 Other disorders of central nervous system	0.004	0.995	0.000
G53.8 Other cranial nerve disorders in other diseases classified elsewhere	0.004	0.995	0.000
G53.3 Multiple cranial nerve palsies in neoplastic disease	0.004	0.995	0.000
G53.2 Multiple cranial nerve palsies in sarcoidosis	0.004	0.995	0.000
G53.1 Multiple cranial nerve palsies in infectious and parasitic diseases classified elsewhere	0.004	0.995	0.000
G61.8 Other inflammatory polyneuropathies	0.004	0.995	0.000
G50.9 Disorder of trigeminal nerve, unspecified	0.004	0.995	0.000
H53.3 Other disorders of binocular vision	0.000	0.995	0.004
O61.1 Failed instrumental induction of labour	0.004	0.995	0.000
G58.9 Mononeuropathy, unspecified	0.004	0.995	0.000
G70 Myasthenia gravis and other myoneural disorders	0.004	0.995	0.000
Z57.2 Occupational exposure to dust	0.004	0.995	0.000
G60 Hereditary and idiopathic neuropathy	0.004	0.995	0.000
G11.4 Hereditary spastic paraplegia	0.004	0.996	0.000
O62.2 Other uterine inertia	0.004	0.996	0.000
O62.1 Secondary uterine inertia	0.004	0.996	0.000
G59.0 Diabetic mononeuropathy	0.004	0.996	0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.004	0.996	0.000
M23.3 Other meniscus derangements	0.004	0.996	0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.004	0.996	0.000
M23 Internal derangement of knee	0.004	0.996	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.004	0.996	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.004	0.996	0.000
G93.2 Benign intracranial hypertension	0.004	0.996	0.000
O62.8 Other abnormalities of forces of labour	0.004	0.996	0.000
O71.7 Obstetric haematoma of pelvis	0.004	0.996	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.004	0.996	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.004	0.996	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.004	0.996	0.000
G64 Other disorders of peripheral nervous system	0.004	0.996	0.000
G06.1 Intraspinal abscess and granuloma	0.004	0.996	0.000
G24.0 Drug-induced dystonia	0.004	0.996	0.000
G72.9 Myopathy, unspecified	0.004	0.996	0.000
G97.8 Other postprocedural disorders of nervous system	0.004	0.996	0.000
G50.8 Other disorders of trigeminal nerve	0.004	0.996	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.004	0.996	0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.004	0.996	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.004	0.996	0.000
G06.0 Intracranial abscess and granuloma	0.004	0.996	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.004	0.996	0.000
O66.9 Obstructed labour, unspecified	0.004	0.996	0.000
O66.8 Other specified obstructed labour	0.004	0.996	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.004	0.996	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.004	0.996	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.004	0.996	0.000
O64.2 Obstructed labour due to face presentation	0.004	0.996	0.000
G11.9 Hereditary ataxia, unspecified	0.004	0.996	0.000
G24.9 Dystonia, unspecified	0.004	0.996	0.000
G80.8 Other infantile cerebral palsy	0.004	0.996	0.000
G93.9 Disorder of brain, unspecified	0.004	0.996	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.004	0.996	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.004	0.996	0.000
G50.1 Atypical facial pain	0.004	0.996	0.000
G83.9 Paralytic syndrome, unspecified	0.004	0.996	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.004	0.996	0.000
I67.2 Cerebral atherosclerosis	0.004	0.996	0.000
G24.4 Idiopathic orofacial dystonia	0.004	0.996	0.000
G24.2 Idiopathic nonfamilial dystonia	0.004	0.996	0.000
G61.1 Serum neuropathy	0.004	0.996	0.000
O64.5 Obstructed labour due to compound presentation	0.004	0.996	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.004	0.996	0.000
G53.0 Postzoster neuralgia	0.004	0.996	0.000
G11.8 Other hereditary ataxias	0.004	0.996	0.000
G11.3 Cerebellar ataxia with defective DNA repair	0.004	0.996	0.000
G11.2 Late-onset cerebellar ataxia	0.004	0.996	0.000
G11.0 Congenital nonprogressive ataxia	0.004	0.996	0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.004	0.996	0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
H53.1 Subjective visual disturbances	0.000	0.996	0.004
O66.3 Obstructed labour due to other abnormalities of foetus	0.004	0.996	0.000
O66.2 Obstructed labour due to unusually large foetus	0.004	0.996	0.000
O66.1 Obstructed labour due to locked twins	0.004	0.996	0.000
G58.7 Mononeuritis multiplex	0.004	0.996	0.000
O62.3 Precipitate labour	0.004	0.996	0.000
G03.9 Meningitis, unspecified	0.004	0.996	0.000
G80.2 Infantile hemiplegia	0.004	0.996	0.000
G80.0 Spastic cerebral palsy	0.004	0.996	0.000
G93.7 Reye's syndrome	0.004	0.996	0.000
O64.4 Obstructed labour due to shoulder presentation	0.004	0.996	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.004	0.996	0.000
G13.0 Paraneoplastic neuromyopathy and neuropathy	0.004	0.996	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.004	0.996	0.000
G72.0 Drug-induced myopathy	0.004	0.996	0.000
O71.8 Other specified obstetric trauma	0.004	0.996	0.000
G04.0 Acute disseminated encephalitis	0.004	0.996	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.004	0.996	0.000
G80.4 Ataxic cerebral palsy	0.004	0.996	0.000
G80.3 Dyskinetic cerebral palsy	0.004	0.996	0.000
O64.3 Obstructed labour due to brow presentation	0.004	0.996	0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.004	0.996	0.000
G06.2 Extradural and subdural abscess, unspecified	0.004	0.996	0.000
G24.8 Other dystonia	0.004	0.996	0.000
G57.0 Lesion of sciatic nerve	0.004	0.996	0.000
G72.1 Alcoholic myopathy	0.004	0.996	0.000
G24.3 Spasmodic torticollis	0.004	0.996	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.004	0.996	0.000
H54.0 Blindness, both eyes	0.000	0.996	0.004
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere	0.004	0.996	0.000
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema	0.004	0.996	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.004	0.996	0.000
W19.9 Unspecified place	0.000	0.996	0.004
W19.6 Industrial and construction area	0.000	0.996	0.004
G04.1 Tropical spastic paraplegia	0.004	0.996	0.000
G80.1 Spastic diplegia	0.004	0.996	0.000
O63.1 Prolonged second stage (of labour)	0.004	0.996	0.000
O66.4 Failed trial of labour, unspecified	0.004	0.996	0.000
G11.1 Early-onset cerebellar ataxia	0.004	0.996	0.000
G24.5 Blepharospasm	0.004	0.996	0.000
G57.8 Other mononeuropathies of lower limb	0.004	0.996	0.000
G83.4 Cauda equina syndrome	0.004	0.996	0.000
G95.9 Disease of spinal cord, unspecified	0.004	0.996	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.004	0.996	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.004	0.996	0.000
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease	0.004	0.996	0.000
G83.3 Monoplegia, unspecified	0.004	0.996	0.000
G95.1 Vascular myelopathies	0.004	0.996	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.000	0.996	0.004
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.004	0.996	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.004	0.996	0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.004	0.996	0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.004	0.996	0.000
G72.3 Periodic paralysis	0.004	0.996	0.000
G72.2 Myopathy due to other toxic agents	0.004	0.996	0.000
H53.8 Other visual disturbances	0.000	0.996	0.004
H54.1 Blindness, one eye, low vision, other eye	0.000	0.996	0.004
G80.9 Infantile cerebral palsy, unspecified	0.004	0.996	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.004	0.996	0.000
G82 Paraplegia and tetraplegia	0.004	0.996	0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.004	0.996	0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.004	0.996	0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
G72.8 Other specified myopathies	0.004	0.996	0.000
G83.5 Locked-in syndrome	0.004	0.996	0.000
G83.0 Diplegia of upper limbs	0.004	0.996	0.000
G03.8 Meningitis due to other specified causes	0.004	0.996	0.000
G03.2 Benign recurrent meningitis [Mollaret]	0.004	0.996	0.000
G03.1 Chronic meningitis	0.004	0.996	0.000
G90.3 Multisystem degeneration	0.004	0.996	0.000
M23.4 Loose body in knee	0.004	0.996	0.000
C67 Malignant neoplasm of bladder	0.004	0.996	0.000
G24.1 Idiopathic familial dystonia	0.004	0.996	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.004	0.996	0.000
G95.8 Other specified diseases of spinal cord	0.004	0.996	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.004	0.996	0.000
G93.5 Compression of brain	0.004	0.996	0.000
G94.1 Hydrocephalus in neoplastic disease	0.004	0.996	0.000
G71.1 Myotonic disorders	0.004	0.996	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.004	0.996	0.000
G00.2 Streptococcal meningitis	0.004	0.996	0.000
G57.4 Lesion of medial popliteal nerve	0.004	0.996	0.000
G57.2 Lesion of femoral nerve	0.004	0.996	0.000
G72.4 Inflammatory myopathy, not elsewhere classified	0.004	0.996	0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
G02.1 Meningitis in mycoses	0.004	0.996	0.000
G57.1 Meralgia paraesthetica	0.004	0.996	0.000
H54.6 Unqualified visual loss, one eye	0.000	0.996	0.004
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.004	0.996	0.000
G57.5 Tarsal tunnel syndrome	0.004	0.996	0.000
G70.9 Myoneural disorder, unspecified	0.004	0.996	0.000
G93.6 Cerebral oedema	0.004	0.996	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.004	0.996	0.000
G00.1 Pneumococcal meningitis	0.004	0.996	0.000
G63.2 Diabetic polyneuropathy	0.004	0.996	0.000
G71.3 Mitochondrial myopathy, not elsewhere classified	0.004	0.996	0.000
G90.4 Autonomic dysreflexia	0.004	0.996	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.004	0.996	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.003	0.996	0.000
G83.2 Monoplegia of upper limb	0.003	0.996	0.000
G93.8 Other specified disorders of brain	0.004	0.996	0.000
W19.3 Sports and athletics area	0.000	0.996	0.004
G00.0 Haemophilus meningitis	0.003	0.996	0.000
G71.9 Primary disorder of muscle, unspecified	0.003	0.996	0.000
G71.8 Other primary disorders of muscles	0.003	0.996	0.000
G71.2 Congenital myopathies	0.003	0.996	0.000
H54.3 Unqualified visual loss, both eyes	0.000	0.996	0.004
G02.0 Meningitis in viral diseases classified elsewhere	0.003	0.996	0.000
G03.0 Nonpyogenic meningitis	0.003	0.996	0.000
G83.8 Other specified paralytic syndromes	0.003	0.996	0.000
W19.8 Other specified place	0.000	0.996	0.004
W19.5 Trade and service area	0.000	0.996	0.004
W19.0 Home	0.000	0.996	0.004
W19.7 Farm	0.000	0.996	0.004
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.004	0.996	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.003	0.996	0.000
G30 Alzheimer's disease	0.004	0.996	0.000
G60.0 Hereditary motor and sensory neuropathy	0.003	0.996	0.000
G00.3 Staphylococcal meningitis	0.003	0.996	0.000
G57.9 Mononeuropathy of lower limb, unspecified	0.003	0.996	0.000
G57.3 Lesion of lateral popliteal nerve	0.003	0.996	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.003	0.996	0.000
G63.6 Polyneuropathy in other musculoskeletal disorders	0.003	0.996	0.000
G63.5 Polyneuropathy in systemic connective tissue disorders	0.003	0.996	0.000
G63.4 Polyneuropathy in nutritional deficiency	0.003	0.996	0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.003	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations