TreeWAS – Variant ID: rs4984499

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T43.2 Other and unspecified antidepressants	0.000	0.698	0.302
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.699	0.301
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.721	0.279
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.726	0.274
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.741	0.259
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.745	0.254
T43.9 Psychotropic drug, unspecified	0.000	0.778	0.222
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.780	0.220
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.784	0.216
T43.6 Psychostimulants with abuse potential	0.000	0.784	0.215
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.838	0.162
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.854	0.146
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.865	0.135
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.868	0.132
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.871	0.129
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.871	0.129
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.874	0.126
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.878	0.122
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.880	0.120
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.881	0.119
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.884	0.116
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.884	0.116
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.886	0.114
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.887	0.113
T38.1 Thyroid hormones and substitutes	0.000	0.887	0.113
T42.4 Benzodiazepines	0.000	0.887	0.113
T45.0 Antiallergic and antiemetic drugs	0.000	0.889	0.111
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.889	0.111
T50.4 Drugs affecting uric acid metabolism	0.000	0.889	0.110
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.891	0.109
T50.7 Analeptics and opioid receptor antagonists	0.000	0.895	0.105
T50.5 Appetite depressants	0.000	0.895	0.105
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.895	0.105
T50.0 Mineralocorticoids and their antagonists	0.000	0.895	0.105
T50.1 Loop [high-ceiling] diuretics	0.000	0.897	0.103
T50.8 Diagnostic agents	0.000	0.897	0.102
T45.5 Anticoagulants	0.000	0.899	0.101
T42.1 Iminostilbenes	0.000	0.900	0.100
T42.3 Barbiturates	0.000	0.904	0.095
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.905	0.095
T45.8 Other primarily systemic and haematological agents	0.000	0.905	0.095
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.905	0.095
T45.6 Fibrinolysis-affecting drugs	0.000	0.905	0.095
T45.4 Iron and its compounds	0.000	0.905	0.095
T45.3 Enzymes, not elsewhere classified	0.000	0.905	0.095
T40.2 Other opioids	0.000	0.905	0.095
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.905	0.094
T38.0 Glucocorticoids and synthetic analogues	0.000	0.906	0.094
T40.6 Other and unspecified narcotics	0.000	0.906	0.094
T45.2 Vitamins, not elsewhere classified	0.000	0.907	0.093
T38.9 Other and unspecified hormone antagonists	0.000	0.907	0.093
T38.7 Androgens and anabolic congeners	0.000	0.907	0.093
T38.5 Other oestrogens and progestogens	0.000	0.907	0.093
T38.4 Oral contraceptives	0.000	0.907	0.093
T38.2 Antithyroid drugs	0.000	0.907	0.093
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.907	0.092
T42.2 Succinimides and oxazolidinediones	0.000	0.907	0.092
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.908	0.092
T48.5 Anti-common-cold drugs	0.000	0.909	0.091
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.909	0.091
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.910	0.090
T39.4 Antirheumatics, not elsewhere classified	0.000	0.910	0.090
T39.2 Pyrazolone derivatives	0.000	0.910	0.090
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.910	0.090
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.910	0.090
T40.5 Cocaine	0.000	0.911	0.089
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.912	0.087
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.913	0.087
T40.8 Lysergide [LSD]	0.000	0.913	0.087
T40.7 Cannabis (derivatives)	0.000	0.913	0.087
T40.0 Opium	0.000	0.913	0.087
T40.1 Heroin	0.000	0.913	0.087
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.913	0.087
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.914	0.086
T37.5 Antiviral drugs	0.000	0.914	0.086
T37.4 Anthelminthics	0.000	0.914	0.086
T37.3 Other antiprotozoal drugs	0.000	0.914	0.086
T37.1 Antimycobacterial drugs	0.000	0.914	0.086
T37.0 Sulphonamides	0.000	0.914	0.086
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.915	0.085
T48.4 Expectorants	0.000	0.915	0.085
T48.3 Antitussives	0.000	0.915	0.085
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.915	0.085
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.915	0.085
T48.0 Oxytocic drugs	0.000	0.915	0.085
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.915	0.085
T40.4 Other synthetic narcotics	0.000	0.916	0.084
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.916	0.084
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.916	0.084
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.916	0.084
T39.0 Salicylates	0.000	0.916	0.084
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.916	0.083
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.916	0.083
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.916	0.083
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.916	0.083
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.916	0.083
T44.0 Anticholinesterase agents	0.000	0.916	0.083
T42.0 Hydantoin derivatives	0.000	0.917	0.083
T49.9 Topical agent, unspecified	0.000	0.919	0.081
T49.8 Other topical agents	0.000	0.919	0.081
T49.7 Dental drugs, topically applied	0.000	0.919	0.081
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.919	0.081
T49.5 Ophthalmological drugs and preparations	0.000	0.919	0.081
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.919	0.081
T49.3 Emollients, demulcents and protectants	0.000	0.919	0.081
T49.2 Local astringents and local detergents	0.000	0.919	0.081
T49.1 Antipruritics	0.000	0.919	0.081
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.919	0.080
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.920	0.080
T41.5 Therapeutic gases	0.000	0.920	0.079
T41.4 Anaesthetic, unspecified	0.000	0.920	0.079
T41.3 Local anaesthetics	0.000	0.920	0.079
T41.1 Intravenous anaesthetics	0.000	0.920	0.079
T41.0 Inhaled anaesthetics	0.000	0.920	0.079
T36 Poisoning by systemic antibiotics	0.000	0.921	0.079
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.922	0.078
T40.3 Methadone	0.000	0.922	0.078
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.925	0.074
T41.2 Other and unspecified general anaesthetics	0.000	0.926	0.074
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.928	0.072
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.931	0.068
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.936	0.064
T36.4 Tetracyclines	0.000	0.939	0.061
T47.2 Stimulant laxatives	0.000	0.942	0.058
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.942	0.058
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.942	0.058
T47.7 Emetics	0.000	0.942	0.058
T47.5 Digestants	0.000	0.942	0.058
T47.3 Saline and osmotic laxatives	0.000	0.942	0.058
T36.9 Systemic antibiotic, unspecified	0.000	0.943	0.057
T36.7 Antifungal antibiotics, systemically used	0.000	0.943	0.057
T36.6 Rifamycins	0.000	0.943	0.057
T36.5 Aminoglycosides	0.000	0.943	0.057
T36.2 Chloramphenicol group	0.000	0.943	0.057
T47.4 Other laxatives	0.000	0.944	0.055
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.945	0.055
T47.6 Antidiarrhoeal drugs	0.000	0.945	0.054
T36.8 Other systemic antibiotics	0.001	0.947	0.053
T36.3 Macrolides	0.001	0.948	0.052
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.949	0.051
E86 Volume depletion	0.000	0.951	0.049
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.951	0.049
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.954	0.046
T46.7 Peripheral vasodilators	0.000	0.954	0.046
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.954	0.046
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.955	0.045
T47.0 Histamine H(2)-receptor antagonists	0.001	0.956	0.044
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.957	0.043
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.958	0.041
T46.1 Calcium-channel blockers	0.000	0.959	0.041
T39.1 4-Aminophenol derivatives	0.000	0.960	0.040
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.962	0.037
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.963	0.037
T36.0 Penicillins	0.001	0.968	0.031
S82.60 Fracture of lateral malleolus (closed)	0.018	0.982	0.000
D12.0 Caecum	0.000	0.984	0.016
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.985	0.015
R63.0 Anorexia	0.000	0.986	0.014
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.987	0.013
Y57.9 Drug or medicament, unspecified	0.013	0.987	0.000
C82.0 Small cleaved cell, follicular	0.000	0.988	0.012
C82.2 Large cell, follicular	0.000	0.988	0.012
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.988	0.012
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.990	0.010
C82.6 Cutaneous follicle centre lymphoma	0.000	0.990	0.010
C82.5 Diffuse follicle centre lymphoma	0.000	0.990	0.010
M24.02 Loose body in joint (Upper arm)	0.009	0.991	0.000
C82.4 Follicular lymphoma grade IIIb	0.000	0.991	0.009
M24.0 Loose body in joint	0.009	0.991	0.000
M24.07 Loose body in joint (Ankle and foot)	0.008	0.992	0.000
M84.03 Malunion of fracture (Forearm)	0.000	0.992	0.008
C62.9 Testis, unspecified	0.008	0.992	0.000
C82.3 Follicular lymphoma grade IIIa	0.000	0.992	0.008
M24.04 Loose body in joint (Hand)	0.007	0.993	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.007	0.993	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.000	0.993	0.007
S82.6 Fracture of lateral malleolus	0.007	0.993	0.000
M24.09 Loose body in joint (Site unspecified)	0.006	0.994	0.000
M24.08 Loose body in joint (Other)	0.006	0.994	0.000
M24.06 Loose body in joint-Lower leg	0.006	0.994	0.000
M24.00 Loose body in joint (Multiple sites)	0.006	0.994	0.000
M24.03 Loose body in joint (Forearm)	0.006	0.994	0.000
N03.9 Unspecified	0.000	0.994	0.006
M24.01 Loose body in joint (Shoulder region)	0.005	0.995	0.000
Y45.2 Propionic acid derivatives	0.000	0.995	0.005
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.995	0.005
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.005	0.995	0.000
M24.1 Other articular cartilage disorders	0.005	0.995	0.000
L30.9 Dermatitis, unspecified	0.000	0.995	0.005
I73.9 Peripheral vascular disease, unspecified	0.000	0.995	0.005
R63.3 Feeding difficulties and mismanagement	0.000	0.995	0.005
M24 Other specific joint derangements	0.005	0.995	0.000
R63 Symptoms and signs concerning food and fluid intake	0.000	0.995	0.005
S82.61 Fracture of lateral malleolus (open)	0.004	0.995	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.004	0.996	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.004	0.996	0.000
C34.1 Upper lobe, bronchus or lung	0.000	0.996	0.004
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.996	0.004
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.004	0.996	0.000
M24.6 Ankylosis of joint	0.004	0.996	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.996	0.004
R63.1 Polydipsia	0.000	0.996	0.004
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
M24.9 Joint derangement, unspecified	0.004	0.996	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.004	0.996	0.000
M24.18 Other articular cartilage disorders (Other)	0.004	0.996	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.004	0.996	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.004	0.996	0.000
M24.14 Other articular cartilage disorders (Hand)	0.004	0.996	0.000
Z13.6 Special screening examination for cardiovascular disorders	0.000	0.996	0.004
R63.6 Insufficient intake of food and water due to self neglect	0.000	0.996	0.004
M24.13 Other articular cartilage disorders (Forearm)	0.004	0.996	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.004	0.996	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.004	0.996	0.000
M24.7 Protrusio acetabuli	0.004	0.996	0.000
I50.0 Congestive heart failure	0.000	0.996	0.004
R63.2 Polyphagia	0.000	0.996	0.004
M24.64 Ankylosis of joint (Hand)	0.003	0.996	0.000
R63.4 Abnormal weight loss	0.000	0.996	0.004
K75.0 Abscess of liver	0.000	0.996	0.004
E05.9 Thyrotoxicosis, unspecified	0.000	0.997	0.003
M24.5 Contracture of joint	0.003	0.997	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.003	0.997	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.003	0.997	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.003	0.997	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.003	0.997	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.003	0.997	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
M24.94 Joint derangement, unspecified (Hand)	0.003	0.997	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.003	0.997	0.000
M24.68 Ankylosis of joint (Other)	0.003	0.997	0.000
M24.63 Ankylosis of joint (Forearm)	0.003	0.997	0.000
M24.62 Ankylosis of joint (Upper arm)	0.003	0.997	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.003	0.997	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.003	0.997	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.003	0.997	0.000
E61.1 Iron deficiency	0.003	0.997	0.000
I08.0 Disorders of both mitral and aortic valves	0.000	0.997	0.003
M24.66 Ankylosis of joint (Lower leg)	0.003	0.997	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.003	0.997	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.003	0.997	0.000
S01.8 Open wound of other parts of head	0.000	0.997	0.003
M24.99 Joint derangement, unspecified (Site unspecified)	0.003	0.997	0.000
M24.98 Joint derangement, unspecified (Other)	0.003	0.997	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.003	0.997	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.003	0.997	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.003	0.997	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.003	0.997	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.003	0.997	0.000
I08 Multiple valve diseases	0.000	0.997	0.003
M24.55 Contracture of joint (Pelvic region and thigh)	0.003	0.997	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.003	0.997	0.000
D32.1 Spinal meninges	0.003	0.997	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.003	0.997	0.000
C62 Malignant neoplasm of testis	0.003	0.997	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.003	0.997	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.003	0.997	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.003	0.997	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.003	0.997	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.003	0.997	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.003	0.997	0.000
M24.79 Protrusio acetabuli-Site unspec	0.003	0.997	0.000
M24.78 Protrusio acetabuli-Other	0.003	0.997	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.003	0.997	0.000
M24.76 Protrusio acetabuli-Lower leg	0.003	0.997	0.000
M24.74 Protrusio acetabuli-Hand	0.003	0.997	0.000
M24.73 Protrusio acetabuli-Forearm	0.003	0.997	0.000
M24.72 Protrusio acetabuli-Upper arm	0.003	0.997	0.000
M24.71 Protrusio acetabuli-Shldr region	0.003	0.997	0.000
M24.70 Protrusio acetabuli-Mult sites	0.003	0.997	0.000
D32.9 Meninges, unspecified	0.003	0.997	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.003	0.997	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.003	0.997	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.997	0.003
I07.1 Tricuspid insufficiency	0.000	0.997	0.003
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.000	0.997	0.003
D32.0 Cerebral meninges	0.003	0.997	0.000
M24.59 Contracture of joint (Site unspecified)	0.003	0.997	0.000
M24.58 Contracture of joint (Other)	0.003	0.997	0.000
M24.53 Contracture of joint (Forearm)	0.003	0.997	0.000
M24.50 Contracture of joint (Multiple sites)	0.003	0.997	0.000
D32 Benign neoplasm of meninges	0.003	0.997	0.000
S02.10 Fracture of base of skull (closed)	0.000	0.997	0.003
M24.52 Contracture of joint (Upper arm)	0.002	0.997	0.000
F20.9 Schizophrenia, unspecified	0.000	0.997	0.003
M24.51 Contracture of joint (Shoulder region)	0.002	0.997	0.000
M24.56 Contracture of joint (Lower leg)	0.002	0.997	0.000
M25.86 Other specified joint disorders (Lower leg)	0.000	0.998	0.002
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.002	0.998	0.000
M24.57 Contracture of joint (Ankle and foot)	0.002	0.998	0.000
C62.0 Undescended testis	0.002	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.002	0.998	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.998	0.002
G31.2 Degeneration of nervous system due to alcohol	0.000	0.998	0.002
R09.0 Asphyxia	0.000	0.998	0.002
K75.9 Inflammatory liver disease, unspecified	0.000	0.998	0.002
N99.3 Prolapse of vaginal vault after hysterectomy	0.002	0.998	0.000
G93.9 Disorder of brain, unspecified	0.000	0.998	0.002
G31.0 Circumscribed brain atrophy	0.000	0.998	0.002
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.998	0.002
M25.84 Other specified joint disorders (Hand)	0.000	0.998	0.002
O66.0 Obstructed labour due to shoulder dystocia	0.000	0.998	0.002
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.000	0.998	0.002
N99.5 Malfunction of external stoma of urinary tract	0.002	0.998	0.000
M24.54 Contracture of joint (Hand)	0.002	0.998	0.000
H04.5 Stenosis and insufficiency of lachrymal passages	0.002	0.998	0.000
I08.9 Multiple valve disease, unspecified	0.000	0.998	0.002
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.998	0.002
I07 Rheumatic tricuspid valve diseases	0.000	0.998	0.002
L30 Other dermatitis	0.000	0.998	0.002
M47.80 Other spondylosis (Multiple sites in spine)	0.002	0.998	0.000
G30.9 Alzheimer's disease, unspecified	0.000	0.998	0.002
L30.3 Infective dermatitis	0.000	0.998	0.002
D35.0 Adrenal gland	0.000	0.998	0.002
M24.2 Disorder of ligament	0.002	0.998	0.000
D26.1 Corpus uteri	0.000	0.998	0.002
E80.4 Gilbert's syndrome	0.000	0.998	0.002
R63.5 Abnormal weight gain	0.001	0.998	0.002
M84.0 Malunion of fracture	0.000	0.998	0.002
K75 Other inflammatory liver diseases	0.000	0.998	0.002
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.000	0.998	0.002
C21.0 Anus, unspecified	0.000	0.998	0.002
C18.2 Ascending colon	0.002	0.998	0.000
G24.5 Blepharospasm	0.002	0.998	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.998	0.002
I08.8 Other multiple valve diseases	0.000	0.998	0.002
C62.1 Descended testis	0.002	0.998	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.000	0.998	0.002
Y57.7 Vitamins, not elsewhere classified	0.002	0.998	0.000
Y57.4 Pharmaceutical excipients	0.002	0.998	0.000
Y57.3 Alcohol deterrents	0.002	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
Y57.1 Lipotropic drugs	0.002	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.002	0.998	0.000
G30 Alzheimer's disease	0.000	0.998	0.002
O66 Other obstructed labour	0.000	0.998	0.002
H50.1 Divergent concomitant strabismus	0.000	0.998	0.002
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.000	0.998	0.002
S51.0 Open wound of elbow	0.000	0.998	0.002
C34.0 Main bronchus	0.000	0.998	0.002
U81.0 Vancomycin resistant agent	0.000	0.998	0.002
N03 Chronic nephritic syndrome	0.000	0.998	0.002
G30-G32 Other degenerative diseases of the nervous system	0.000	0.998	0.002
G30.0 Alzheimer's disease with early onset	0.000	0.998	0.002
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.002	0.998	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.998	0.002
I35.8 Other aortic valve disorders	0.000	0.998	0.002
N13.4 Hydroureter	0.000	0.998	0.002
E80.6 Other disorders of bilirubin metabolism	0.000	0.998	0.002
I07.9 Tricuspid valve disease, unspecified	0.000	0.998	0.002
I07.8 Other tricuspid valve diseases	0.000	0.998	0.002
I07.2 Tricuspid stenosis with insufficiency	0.000	0.998	0.002
I07.0 Tricuspid stenosis	0.000	0.998	0.002
L51.9 Erythema multiforme, unspecified	0.000	0.998	0.002
L30.5 Pityriasis alba	0.000	0.998	0.002
L30.2 Cutaneous autosensitisation	0.000	0.998	0.002
L30.1 Dyshidrosis [pompholyx]	0.000	0.998	0.002
M24.29 Disorder of ligament (Site unspecified)	0.002	0.998	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.002	0.998	0.000
M24.22 Disorder of ligament (Upper arm)	0.002	0.998	0.000
M24.20 Disorder of ligament (Multiple sites)	0.002	0.998	0.000
G93.2 Benign intracranial hypertension	0.000	0.998	0.002
N94.1 Dyspareunia	0.000	0.998	0.002
M24.23 Disorder of ligament (Forearm)	0.002	0.998	0.000
D35.2 Pituitary gland	0.000	0.998	0.002
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.998	0.002
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.998	0.002
M84.09 Malunion of fracture (Site unspecified)	0.000	0.998	0.002
M84.00 Malunion of fracture (Multiple sites)	0.000	0.998	0.002
G93.8 Other specified disorders of brain	0.000	0.998	0.002
K75.2 Nonspecific reactive hepatitis	0.000	0.998	0.002
K75.1 Phlebitis of portal vein	0.000	0.998	0.002
M24.26 Disorder of ligament (Lower leg)	0.002	0.998	0.000
M24.21 Disorder of ligament (Shoulder region)	0.002	0.998	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.000	0.998	0.002
O66.4 Failed trial of labour, unspecified	0.000	0.998	0.002
O71.4 Obstetric high vaginal laceration alone	0.000	0.998	0.002
S51.8 Open wound of other parts of forearm	0.000	0.998	0.002
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.000	0.998	0.002
O66.9 Obstructed labour, unspecified	0.000	0.998	0.002
N03.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.998	0.002
Y57.8 Other drugs and medicaments	0.002	0.998	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.998	0.002
D22.3 Melanocytic naevi of other and unspecified parts of face	0.002	0.998	0.000
L30.4 Erythema intertrigo	0.000	0.998	0.002
I05-I09 Chronic rheumatic heart diseases	0.000	0.998	0.002
O66.3 Obstructed labour due to other abnormalities of foetus	0.000	0.998	0.002
O66.2 Obstructed labour due to unusually large foetus	0.000	0.998	0.002
O66.1 Obstructed labour due to locked twins	0.000	0.998	0.002
M25.88 Other specified joint disorders (Other)	0.000	0.998	0.002
L30.8 Other specified dermatitis	0.000	0.998	0.002
C34 Malignant neoplasm of bronchus and lung	0.000	0.998	0.002
M24.24 Disorder of ligament (Hand)	0.001	0.998	0.001
K73.9 Chronic hepatitis, unspecified	0.000	0.998	0.002
O71.8 Other specified obstetric trauma	0.000	0.998	0.002
M84.02 Malunion of fracture (Upper arm)	0.000	0.998	0.001
M84.01 Malunion of fracture (Shoulder region)	0.000	0.998	0.002
G31.8 Other specified degenerative diseases of nervous system	0.000	0.998	0.002
N03.7 Diffuse crescentic glomerulonephritis	0.000	0.998	0.001
N03.6 Dense deposit disease	0.000	0.998	0.001
N03.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.998	0.001
N03.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.998	0.001
N03.2 Diffuse membranous glomerulonephritis	0.000	0.998	0.001
N03.0 Minor glomerular abnormality	0.000	0.998	0.001
S10.9 Superficial injury of neck, part unspecified	0.000	0.998	0.002
Y57.5 X-ray contrast media	0.002	0.998	0.000
E61 Deficiency of other nutrient elements	0.002	0.998	0.000
G30.1 Alzheimer's disease with late onset	0.000	0.998	0.002
M82.1 Osteoporosis in endocrine disorders	0.000	0.998	0.002
Q61.0 Congenital single renal cyst	0.002	0.998	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.998	0.002
M84.06 Malunion of fracture (Lower leg)	0.000	0.998	0.001
R09.2 Respiratory arrest	0.000	0.998	0.002
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.000	0.998	0.002
M84.05 Malunion of fracture (Pelvic region and thigh)	0.000	0.998	0.001
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.998	0.001
M24.8 Other specific joint derangements, not elsewhere classified	0.001	0.998	0.001
Y57.6 Other diagnostic agents	0.001	0.998	0.000
L30.0 Nummular dermatitis	0.000	0.998	0.001
M13.91 Arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
M24.28 Disorder of ligament (Other)	0.001	0.998	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.998	0.002
D11.0 Parotid gland	0.000	0.998	0.002
O66.8 Other specified obstructed labour	0.000	0.998	0.001
I06 Rheumatic aortic valve diseases	0.000	0.998	0.001
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.998	0.002
N99.2 Postprocedural adhesions of vagina	0.002	0.998	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.001	0.998	0.000
M84.08 Malunion of fracture (Other)	0.000	0.998	0.001
D31.3 Choroid	0.002	0.998	0.000
G30.8 Other Alzheimer's disease	0.000	0.998	0.001
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.998	0.002
M84.04 Malunion of fracture (Hand)	0.000	0.998	0.001
S82.00 Fracture of patella (closed)	0.000	0.998	0.002
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.000	0.998	0.001
M25.83 Other specified joint disorders (Forearm)	0.000	0.998	0.001
D07.5 Prostate	0.000	0.998	0.002
M25.8 Other specified joint disorders	0.000	0.998	0.002
N03.8 Other	0.000	0.998	0.001
G93 Other disorders of brain	0.000	0.998	0.002
K75.4 Autoimmune hepatitis	0.000	0.998	0.001
N03.1 Focal and segmental glomerular lesions	0.000	0.998	0.001
O64.1 Obstructed labour due to breech presentation	0.001	0.998	0.000
I69.3 Sequelae of cerebral infarction	0.001	0.999	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.999	0.001
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.000	0.999	0.001
M82.18 Osteoporosis in endocrine disorders (Other)	0.000	0.999	0.001
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.000	0.999	0.001
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.000	0.999	0.001
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.000	0.999	0.001
M82.14 Osteoporosis in endocrine disorders (Hand)	0.000	0.999	0.001
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.000	0.999	0.001
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.000	0.999	0.001
C34.9 Bronchus or lung, unspecified	0.000	0.999	0.001
D26.0 Cervix uteri	0.000	0.999	0.001
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.999	0.001
E61.9 Deficiency of nutrient element, unspecified	0.001	0.999	0.000
E61.8 Deficiency of other specified nutrient elements	0.001	0.999	0.000
E61.7 Deficiency of multiple nutrient elements	0.001	0.999	0.000
E61.6 Vanadium deficiency	0.001	0.999	0.000
E61.5 Molybdenum deficiency	0.001	0.999	0.000
E61.4 Chromium deficiency	0.001	0.999	0.000
E61.3 Manganese deficiency	0.001	0.999	0.000
E61.0 Copper deficiency	0.001	0.999	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.999	0.001
N81.5 Vaginal enterocele	0.001	0.999	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.001	0.999	0.001
E61.2 Magnesium deficiency	0.001	0.999	0.000
R63.8 Other symptoms and signs concerning food and fluid intake	0.000	0.999	0.001
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.001	0.999	0.001
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.001	0.999	0.001
W13.9 Unspecified place	0.000	0.999	0.001
Z83.3 Family history of diabetes mellitus	0.001	0.999	0.000
C32.9 Larynx, unspecified	0.000	0.999	0.001
I06.1 Rheumatic aortic insufficiency	0.000	0.999	0.001
N60.8 Other benign mammary dysplasias	0.001	0.999	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.001	0.999	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.000	0.999	0.001
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.001	0.999	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.001	0.999	0.001
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.001	0.999	0.001
M79.80 Other specified soft tissue disorders (Multiple sites)	0.000	0.999	0.001
C21.8 Overlapping lesion of rectum, anus and anal canal	0.000	0.999	0.001
I06.8 Other rheumatic aortic valve diseases	0.000	0.999	0.001
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.999	0.001
M75.2 Bicipital tendinitis	0.000	0.999	0.001
I09 Other rheumatic heart diseases	0.000	0.999	0.001
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.999	0.001
C21.1 Anal canal	0.000	0.999	0.001
G93.6 Cerebral oedema	0.000	0.999	0.001
I06.0 Rheumatic aortic stenosis	0.000	0.999	0.001
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.999	0.001
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.000	0.999	0.001
T02.40 Fractures involving multiple regions of both upper limbs (closed)	0.001	0.999	0.000
E80.5 Crigler-Najjar syndrome	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations