TreeWAS – Variant ID: rs5011832

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z90 Acquired absence of organs, not elsewhere classified	1.000	0.000	0.000
Z86 Personal history of certain other diseases	1.000	0.000	0.000
Z90.4 Acquired absence of other parts of digestive tract	0.999	0.001	0.000
Z86.4 Personal history of psychoactive substance abuse	0.999	0.001	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.999	0.001	0.000
Z86.0 Personal history of other neoplasms	0.998	0.002	0.000
Z90.2 Acquired absence of lung [part of]	0.998	0.002	0.000
Z80 Family history of malignant neoplasm	0.995	0.005	0.000
Z98 Other postsurgical states	0.987	0.013	0.000
Z80.3 Family history of malignant neoplasm of breast	0.983	0.017	0.000
Z98.8 Other specified postsurgical states	0.973	0.027	0.000
Z90.3 Acquired absence of part of stomach	0.950	0.050	0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.940	0.060	0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.918	0.082	0.000
D32.0 Cerebral meninges	0.912	0.088	0.000
Z97 Presence of other devices	0.903	0.097	0.000
Z90.7 Acquired absence of genital organ(s)	0.903	0.097	0.000
Z88.5 Personal history of allergy to narcotic agent	0.894	0.106	0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.887	0.113	0.000
Z86.6 Personal history of diseases of the nervous system and sense organs	0.886	0.114	0.000
Z88.7 Personal history of allergy to serum and vaccine	0.882	0.118	0.000
Z98.1 Arthrodesis status	0.881	0.119	0.000
Z88.2 Personal history of allergy to sulphonamides	0.878	0.122	0.000
Z93 Artificial opening status	0.875	0.125	0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.853	0.147	0.000
Z80.8 Family history of malignant neoplasm of other organs or systems	0.846	0.154	0.000
Z94 Transplanted organ and tissue status	0.837	0.163	0.000
D32 Benign neoplasm of meninges	0.809	0.191	0.000
Z94.7 Corneal transplant status	0.803	0.197	0.000
Z97.4 Presence of external hearing-aid	0.793	0.207	0.000
Z80.5 Family history of malignant neoplasm of urinary tract	0.792	0.208	0.000
Z98.2 Presence of cerebrospinal fluid drainage device	0.783	0.217	0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs	0.783	0.217	0.000
D32.9 Meninges, unspecified	0.777	0.223	0.000
Z93.4 Other artificial openings of gastro-intestinal tract status	0.772	0.228	0.000
Z94.1 Heart transplant status	0.771	0.229	0.000
Z97.0 Presence of artificial eye	0.758	0.242	0.000
Z97.5 Presence of (intra-uterine) contraceptive device	0.751	0.249	0.000
Z90.0 Acquired absence of part of head and neck	0.725	0.275	0.000
Z80.4 Family history of malignant neoplasm of genital organs	0.718	0.282	0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues	0.715	0.285	0.000
Z93.2 Ileostomy status	0.714	0.286	0.000
Z93.0 Tracheostomy status	0.714	0.286	0.000
Z80.6 Family history of leukaemia	0.710	0.290	0.000
Z93.5 Cystostomy status	0.706	0.294	0.000
Z93.8 Other artificial opening status	0.693	0.307	0.000
Z93.6 Other artificial openings of urinary tract status	0.678	0.321	0.000
D32.1 Spinal meninges	0.660	0.340	0.000
Z97.1 Presence of artificial limb (complete)(partial)	0.653	0.347	0.000
Z94.2 Lung transplant status	0.650	0.349	0.000
Z81 Family history of mental and behavioural disorders	0.640	0.360	0.000
Z97.2 Presence of dental prosthetic device (complete)(partial)	0.636	0.364	0.000
Z97.3 Presence of spectacles and contact lenses	0.623	0.377	0.000
Z94.9 Transplanted organ and tissue status, unspecified	0.600	0.400	0.000
Z94.6 Bone transplant status	0.600	0.400	0.000
Z94.3 Heart and lungs transplant status	0.600	0.400	0.000
Z80.0 Family history of malignant neoplasm of digestive organs	0.596	0.404	0.000
Z93.9 Artificial opening status, unspecified	0.588	0.412	0.000
Z90.1 Acquired absence of breast(s)	0.579	0.421	0.000
Z80.9 Family history of malignant neoplasm, unspecified	0.557	0.443	0.000
Z94.5 Skin transplant status	0.545	0.455	0.000
Z84 Family history of other conditions	0.498	0.502	0.000
Z97.8 Presence of other specified devices	0.482	0.518	0.000
Z86.7 Personal history of diseases of the circulatory system	0.471	0.529	0.000
Z81.4 Family history of other substance abuse	0.459	0.541	0.000
Z81.3 Family history of other psychoactive substance abuse	0.459	0.541	0.000
Z81.2 Family history of tobacco abuse	0.459	0.541	0.000
Z81.1 Family history of alcohol abuse	0.459	0.541	0.000
Z81.0 Family history of mental retardation	0.459	0.541	0.000
Z94.4 Liver transplant status	0.450	0.550	0.000
Z98.0 Intestinal bypass and anastomosis status	0.438	0.562	0.000
Z93.3 Colostomy status	0.433	0.567	0.000
I10 Essential (primary) hypertension	0.426	0.574	0.000
Z86.5 Personal history of other mental and behavioural disorders	0.422	0.578	0.000
I10-I15 Hypertensive diseases	0.413	0.587	0.000
I12 Hypertensive renal disease	0.406	0.594	0.000
Z90.5 Acquired absence of kidney	0.386	0.614	0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.383	0.617	0.000
I12.9 Hypertensive renal disease without renal failure	0.383	0.617	0.000
Z81.8 Family history of other mental and behavioural disorders	0.382	0.618	0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.379	0.621	0.000
I12.0 Hypertensive renal disease with renal failure	0.374	0.626	0.000
I15 Secondary hypertension	0.368	0.632	0.000
Z84.3 Family history of consanguinity	0.357	0.643	0.000
Z84.0 Family history of diseases of the skin and subcutaneous tissue	0.357	0.643	0.000
Z90.6 Acquired absence of other parts of urinary tract	0.353	0.647	0.000
Z88.6 Personal history of allergy to analgesic agent	0.341	0.659	0.000
Z88.3 Personal history of allergy to other anti-infective agents	0.323	0.677	0.000
Z84.1 Family history of disorders of the kidney and ureter	0.323	0.677	0.000
Z84.8 Family history of other specified conditions	0.317	0.682	0.000
I13 Hypertensive heart and renal disease	0.316	0.683	0.000
I15.8 Other secondary hypertension	0.312	0.688	0.000
I11 Hypertensive heart disease	0.301	0.698	0.000
I15.9 Seconday hypertension, unspecified	0.292	0.708	0.000
I15.2 Hypertension secondary to endocrine disorders	0.275	0.724	0.000
Z84.2 Family history of other diseases of the genito-urinary system	0.272	0.727	0.001
I15.1 Hypertension secondary to other renal disorders	0.272	0.728	0.000
Z88.1 Personal history of allergy to other antibiotic agents	0.271	0.729	0.000
I15.0 Renovascular hypertension	0.271	0.729	0.000
Z93.1 Gastrostomy status	0.269	0.731	0.000
Z90.8 Acquired absence of other organs	0.263	0.736	0.000
Z88.0 Personal history of allergy to penicillin	0.263	0.737	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.259	0.741	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.247	0.753	0.000
Z92 Personal history of medical treatment	0.242	0.758	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.241	0.759	0.000
Z92.4 Personal history of major surgery, not elsewhere classified	0.231	0.769	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.227	0.773	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.227	0.773	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.227	0.773	0.000
Z92.8 Personal history of other medical treatment	0.225	0.775	0.000
Z94.0 Kidney transplant status	0.213	0.786	0.000
Z86.1 Personal history of infectious and parasitic diseases	0.212	0.788	0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.187	0.812	0.000
Z92.9 Personal history of medical treatment, unspecified	0.185	0.815	0.000
Z82.2 Family history of deafness and hearing loss	0.182	0.817	0.000
Z92.5 Personal history of rehabilitation measures	0.173	0.827	0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.173	0.827	0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.173	0.827	0.000
Z91 Personal history of risk-factors, not elsewhere classified	0.169	0.830	0.001
Z94.8 Other transplanted organ and tissue status	0.163	0.837	0.000
Z82.1 Family history of blindness and visual loss	0.155	0.845	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.150	0.850	0.000
Z88.4 Personal history of allergy to anaesthetic agent	0.147	0.852	0.001
Z91.8 Personal history of other specified risk-factors, not elsewhere classified	0.145	0.855	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.141	0.859	0.001
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.137	0.863	0.000
H18 Other disorders of cornea	0.133	0.867	0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.132	0.868	0.000
H74 Other disorders of middle ear and mastoid	0.000	0.870	0.130
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.130	0.870	0.000
H17.9 Corneal scar and opacity, unspecified	0.129	0.871	0.000
H17 Corneal scars and opacities	0.129	0.871	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.127	0.873	0.000
H65-H75 Diseases of middle ear and mastoid	0.000	0.875	0.125
H16 Keratitis	0.123	0.877	0.000
H65 Nonsuppurative otitis media	0.000	0.877	0.123
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.878	0.122
J45.9 Asthma, unspecified	0.122	0.878	0.000
Z91.7 Personal history of female genital mutilation	0.121	0.878	0.001
Z91.3 Personal history of unhealthy sleep-wake schedule	0.121	0.878	0.001
H18.2 Other corneal oedema	0.120	0.880	0.000
H18.6 Keratoconus	0.120	0.880	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.881	0.119
H72 Perforation of tympanic membrane	0.000	0.881	0.119
H18.9 Disorder of cornea, unspecified	0.119	0.881	0.000
H18.1 Bullous keratopathy	0.118	0.882	0.000
H74.0 Tympanosclerosis	0.000	0.883	0.117
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.883	0.117
Z99.0 Dependence on aspirator	0.112	0.888	0.000
H18.8 Other specified disorders of cornea	0.112	0.888	0.000
H65.2 Chronic serous otitis media	0.000	0.889	0.111
Z91.4 Personal history of psychological trauma, not elsewhere classified	0.110	0.889	0.001
Z91.2 Personal history of poor personal hygiene	0.109	0.890	0.001
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.109	0.891	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.109	0.891	0.000
H72.0 Central perforation of tympanic membrane	0.000	0.892	0.108
Z99.4 Dependence on artificial heart	0.107	0.892	0.000
H18.0 Corneal pigmentations and deposits	0.107	0.893	0.000
H21 Other disorders of iris and ciliary body	0.106	0.894	0.000
H65.4 Other chronic nonsuppurative otitis media	0.000	0.896	0.104
Z99.9 Dependence on unspecified enabling machine and device	0.104	0.896	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.896	0.104
H72.1 Attic perforation of tympanic membrane	0.000	0.897	0.103
H73 Other disorders of tympanic membrane	0.000	0.898	0.102
H16.3 Interstitial and deep keratitis	0.102	0.898	0.000
Z99.8 Dependence on other enabling machines and devices	0.101	0.899	0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.100	0.900	0.000
H16.0 Corneal ulcer	0.100	0.900	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.901	0.099
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.902	0.098
H16.2 Keratoconjunctivitis	0.097	0.903	0.000
H18.7 Other corneal deformities	0.095	0.905	0.000
H74.4 Polyp of middle ear	0.000	0.905	0.095
H22.1 Iridocyclitis in other diseases classified elsewhere	0.094	0.906	0.000
H74.1 Adhesive middle ear disease	0.000	0.907	0.093
H18.3 Changes in corneal membranes	0.093	0.907	0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen	0.093	0.907	0.000
H16.8 Other keratitis	0.093	0.907	0.000
H17.1 Other central corneal opacity	0.092	0.907	0.000
H17.0 Adherent leukoma	0.092	0.907	0.000
H73.8 Other specified disorders of tympanic membrane	0.000	0.909	0.091
H69 Other disorders of Eustachian tube	0.000	0.909	0.091
H65.0 Acute serous otitis media	0.000	0.910	0.090
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.910	0.090
H68 Eustachian salpingitis and obstruction	0.000	0.910	0.090
H67 Otitis media in diseases classified elsewhere	0.000	0.910	0.090
H17.8 Other corneal scars and opacities	0.089	0.911	0.000
Z82.3 Family history of stroke	0.089	0.911	0.000
Z89 Acquired absence of limb	0.083	0.912	0.006
Z03.4 Observation for suspected myocardial infarction	0.087	0.913	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.087	0.913	0.000
H21.2 Degeneration of iris and ciliary body	0.086	0.914	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.085	0.915	0.000
H16.9 Keratitis, unspecified	0.083	0.916	0.000
H15 Disorders of sclera	0.083	0.917	0.000
Z92.0 Personal history of contraception	0.082	0.917	0.000
Z99.2 Dependence on renal dialysis	0.082	0.917	0.000
H21.0 Hyphaema	0.082	0.918	0.000
H18.5 Hereditary corneal dystrophies	0.082	0.918	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.082	0.918	0.000
H65.1 Other acute nonsuppurative otitis media	0.000	0.919	0.081
H66 Suppurative and unspecified otitis media	0.000	0.920	0.080
H21.4 Pupillary membranes	0.079	0.921	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.078	0.921	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.078	0.921	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.076	0.924	0.000
H16.4 Corneal neovascularisation	0.074	0.926	0.000
H72.8 Other perforations of tympanic membrane	0.000	0.926	0.074
H73.0 Acute myringitis	0.000	0.926	0.073
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.070	0.927	0.003
H72.2 Other marginal perforations of tympanic membrane	0.000	0.928	0.072
Z91.5 Personal history of self-harm	0.071	0.929	0.000
H21.8 Other specified disorders of iris and ciliary body	0.069	0.931	0.000
H70 Mastoiditis and related conditions	0.000	0.931	0.069
H73.1 Chronic myringitis	0.000	0.931	0.068
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.932	0.068
H69.9 Eustachian tube disorder, unspecified	0.000	0.933	0.067
H69.0 Patulous Eustachian tube	0.000	0.935	0.065
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.935	0.064
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.935	0.064
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.935	0.064
H68.1 Obstruction of Eustachian tube	0.000	0.935	0.064
H68.0 Eustachian salpingitis	0.000	0.935	0.064
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.935	0.064
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.935	0.064
J45 Asthma	0.065	0.935	0.000
H69.8 Other specified disorders of Eustachian tube	0.000	0.936	0.064
H66.0 Acute suppurative otitis media	0.000	0.936	0.064
Z89.8 Acquired absence of upper and lower limbs [any level]	0.060	0.936	0.004
Z89.3 Acquired absence of both upper limbs [any level]	0.059	0.936	0.004
Z89.1 Acquired absence of hand and wrist	0.059	0.936	0.004
Z92.2 Personal history of long-term (current) use of other medicaments	0.062	0.938	0.000
Z89.9 Acquired absence of limb, unspecified	0.058	0.938	0.004
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.938	0.062
H66.4 Suppurative otitis media, unspecified	0.000	0.939	0.061
H15.9 Disorder of sclera, unspecified	0.059	0.940	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.059	0.941	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.059	0.941	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.059	0.941	0.000
H15.1 Episcleritis	0.058	0.942	0.000
H15.8 Other disorders of sclera	0.058	0.942	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.057	0.943	0.000
H71 Cholesteatoma of middle ear	0.000	0.944	0.056
H65.3 Chronic mucoid otitis media	0.000	0.946	0.054
H20 Iridocyclitis	0.054	0.946	0.000
Z89.2 Acquired absence of upper limb above wrist	0.048	0.947	0.005
H15.0 Scleritis	0.053	0.947	0.000
H66.3 Other chronic suppurative otitis media	0.000	0.947	0.052
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.948	0.052
H70.8 Other mastoiditis and related conditions	0.000	0.948	0.051
Z83 Family history of other specific disorders	0.051	0.949	0.000
J45.8 Mixed asthma	0.050	0.950	0.000
H70.2 Petrositis	0.000	0.950	0.050
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.049	0.950	0.000
D35.1 Parathyroid gland	0.049	0.951	0.000
H70.0 Acute mastoiditis	0.000	0.952	0.048
H61.2 Impacted cerumen	0.000	0.953	0.047
J45.0 Predominantly allergic asthma	0.047	0.953	0.000
J45.1 Nonallergic asthma	0.045	0.954	0.000
H70.1 Chronic mastoiditis	0.000	0.955	0.044
H21.5 Other adhesions and disruptions of iris and ciliary body	0.043	0.957	0.000
H61 Other disorders of external ear	0.000	0.958	0.042
Chapter VIII Diseases of the ear and mastoid process	0.000	0.959	0.041
Z89.6 Acquired absence of leg above knee	0.036	0.960	0.005
H20.8 Other iridocyclitis	0.040	0.960	0.000
H60-H62 Diseases of external ear	0.000	0.960	0.040
H61.1 Non-infective disorders of pinna	0.000	0.961	0.039
H20.2 Lens-induced iridocyclitis	0.039	0.961	0.000
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.038	0.962	0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.032	0.962	0.006
H70.9 Mastoiditis, unspecified	0.000	0.963	0.037
Z83.0 Family history of human immunodeficiency virus [HIV]	0.036	0.963	0.000
Z03 Medical observation and evaluation for suspected diseases and conditions	0.036	0.964	0.000
H61.3 Acquired stenosis of external ear canal	0.000	0.964	0.036
H20.1 Chronic iridocyclitis	0.036	0.964	0.000
Z83.6 Family history of diseases of the respiratory system	0.036	0.964	0.000
Z03.5 Observation for other suspected cardiovascular diseases	0.035	0.965	0.000
H66.9 Otitis media, unspecified	0.000	0.965	0.035
Z99.3 Dependence on wheelchair	0.035	0.965	0.000
Z92.3 Personal history of irradiation	0.034	0.966	0.000
H11 Other disorders of conjunctiva	0.033	0.967	0.000
H20.0 Acute and subacute iridocyclitis	0.032	0.968	0.000
H11.1 Conjunctival degenerations and deposits	0.030	0.970	0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.030	0.970	0.000
Z85 Personal history of malignant neoplasm	0.030	0.970	0.000
H11.8 Other specified disorders of conjunctiva	0.030	0.970	0.000
Z03.3 Observation for suspected nervous system disorder	0.029	0.971	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.029	0.971	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.000	0.971	0.029
E66.8 Other obesity	0.029	0.971	0.000
Z85.3 Personal history of malignant neoplasm of breast	0.027	0.973	0.000
Z03.9 Observation for suspected disease or condition, unspecified	0.027	0.973	0.000
H11.9 Disorder of conjunctiva, unspecified	0.027	0.973	0.000
H11.0 Pterygium	0.027	0.973	0.000
Z83.1 Family history of other infectious and parasitic diseases	0.027	0.973	0.000
H11.2 Conjunctival scars	0.027	0.973	0.000
H10-H13 Disorders of conjunctiva	0.027	0.973	0.000
H18.4 Corneal degeneration	0.025	0.973	0.002
Z03.2 Observation for suspected mental and behavioural disorders	0.026	0.974	0.000
Z03.0 Observation for suspected tuberculosis	0.026	0.974	0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.026	0.974	0.000
Z89.5 Acquired absence of leg at or below knee	0.020	0.974	0.006
Z89.4 Acquired absence of foot and ankle	0.018	0.976	0.006
Z99.1 Dependence on respirator	0.022	0.977	0.000
Z91.6 Personal history of other physical trauma	0.004	0.977	0.019
H61.0 Perichondritis of external ear	0.000	0.978	0.022
H13 Disorders of conjunctiva in diseases classified elsewhere	0.022	0.978	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.000	0.978	0.022
Z85.0 Personal history of malignant neoplasm of digestive organs	0.022	0.978	0.000
H61.8 Other specified disorders of external ear	0.000	0.978	0.021
H10 Conjunctivitis	0.021	0.979	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.000	0.979	0.021
H62.4 Otitis externa in other diseases classified elsewhere	0.000	0.979	0.021
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.000	0.979	0.021
H62.2 Otitis externa in mycoses	0.000	0.979	0.021
H62.1 Otitis externa in viral diseases classified elsewhere	0.000	0.979	0.021
C78.7 Secondary malignant neoplasm of liver	0.021	0.979	0.000
Z03.1 Observation for suspected malignant neoplasm	0.021	0.979	0.000
H11.3 Conjunctival haemorrhage	0.020	0.980	0.000
Z03.6 Observation for suspected toxic effect from ingested substance	0.020	0.980	0.000
H13.3 Ocular pemphigoid	0.019	0.981	0.000
Z85.5 Personal history of malignant neoplasm of urinary tract	0.019	0.981	0.000
E66 Obesity	0.019	0.981	0.000
Z42.1 Follow-up care involving plastic surgery of breast	0.019	0.981	0.000
H20.9 Iridocyclitis, unspecified	0.017	0.982	0.000
K90.0 Coeliac disease	0.000	0.982	0.018
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.017	0.983	0.000
Chapter VII Diseases of the eye and adnexa	0.017	0.983	0.000
H61.9 Disorder of external ear, unspecified	0.000	0.983	0.016
D35 Benign neoplasm of other and unspecified endocrine glands	0.016	0.984	0.000
Z83.7 Family history of diseases of the digestive system	0.016	0.984	0.000
H10.4 Chronic conjunctivitis	0.016	0.984	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.016	0.984	0.000
H13.8 Other disorders of conjunctiva in diseases classified elsewhere	0.016	0.984	0.000
H13.2 Conjunctivitis in other diseases classified elsewhere	0.016	0.984	0.000
H13.1 Conjunctivitis in infectious and parasitic diseases classified elsewhere	0.016	0.984	0.000
H13.0 Filarial infection of conjunctiva	0.016	0.984	0.000
H10.9 Conjunctivitis, unspecified	0.016	0.984	0.000
H10.5 Blepharoconjunctivitis	0.016	0.984	0.000
Z85.02 Personal history of malignant neoplasm of stomach	0.016	0.984	0.000
H10.3 Acute conjunctivitis, unspecified	0.016	0.984	0.000
H10.8 Other conjunctivitis	0.015	0.984	0.000
H10.2 Other acute conjunctivitis	0.015	0.984	0.000
H10.1 Acute atopic conjunctivitis	0.015	0.984	0.000
H10.0 Mucopurulent conjunctivitis	0.015	0.984	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.016	0.984	0.000
E66.9 Obesity, unspecified	0.015	0.985	0.000
J42 Unspecified chronic bronchitis	0.015	0.985	0.000
Z96 Presence of other functional implants	0.015	0.985	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.015	0.985	0.000
J40-J47 Chronic lower respiratory diseases	0.015	0.985	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.014	0.986	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.014	0.986	0.000
C78.0 Secondary malignant neoplasm of lung	0.014	0.986	0.000
H46 Optic neuritis	0.014	0.986	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.014	0.986	0.000
Z85.9 Personal history of malignant neoplasm, unspecified	0.014	0.986	0.000
E66.1 Drug-induced obesity	0.014	0.986	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.013	0.986	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.013	0.987	0.000
Z42 Follow-up care involving plastic surgery	0.013	0.987	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.013	0.987	0.000
E66.0 Obesity due to excess calories	0.013	0.987	0.000
H47.1 Papilloedema, unspecified	0.013	0.987	0.000
Z83.3 Family history of diabetes mellitus	0.013	0.987	0.000
J46 Status asthmaticus	0.012	0.987	0.000
D35.9 Endocrine gland, unspecified	0.012	0.988	0.000
D35.8 Pluriglandular involvement	0.012	0.988	0.000
D35.7 Other specified endocrine glands	0.012	0.988	0.000
D35.6 Aortic body and other paraganglia	0.012	0.988	0.000
D35.5 Carotid body	0.012	0.988	0.000
D35.4 Pineal gland	0.012	0.988	0.000
D35.3 Craniopharyngeal duct	0.012	0.988	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.012	0.988	0.000
H60 Otitis externa	0.000	0.988	0.011
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.011	0.989	0.000
Z96.5 Presence of tooth-root and mandibular implants	0.011	0.989	0.000
D35.2 Pituitary gland	0.011	0.989	0.000
Z96.9 Presence of functional implant, unspecified	0.011	0.989	0.000
Z37.0 Single live birth	0.000	0.989	0.011
K41 Femoral hernia	0.011	0.989	0.000
H47.2 Optic atrophy	0.011	0.989	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.011	0.989	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.011	0.989	0.000
Z96.3 Presence of artificial larynx	0.011	0.989	0.000
J91 Pleural effusion in conditions classified elsewhere	0.011	0.989	0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.011	0.989	0.000
Z96.4 Presence of endocrine implants	0.010	0.990	0.000
Z85.6 Personal history of leukaemia	0.010	0.990	0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.010	0.990	0.000
D35.0 Adrenal gland	0.010	0.990	0.000
H47.7 Disorder of visual pathways, unspecified	0.010	0.990	0.000
H47.6 Disorders of visual cortex	0.010	0.990	0.000
H47.5 Disorders of other visual pathways	0.010	0.990	0.000
H47.4 Disorders of optic chiasm	0.010	0.990	0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity	0.010	0.990	0.000
E65-E68 Obesity and other hyperalimentation	0.010	0.990	0.000
K90 Intestinal malabsorption	0.000	0.991	0.009
J41 Simple and mucopurulent chronic bronchitis	0.009	0.991	0.000
H40-H42 Glaucoma	0.009	0.991	0.000
Z42.9 Follow-up care involving plastic surgery, unspecified	0.009	0.991	0.000
H60.2 Malignant otitis externa	0.000	0.991	0.009
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.009	0.991	0.000
Z42.8 Follow-up care involving plastic surgery of other body part	0.009	0.991	0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.009	0.991	0.000
H80-H83 Diseases of inner ear	0.000	0.991	0.009
J47 Bronchiectasis	0.009	0.991	0.000
H50 Other strabismus	0.009	0.991	0.000
H60.8 Other otitis externa	0.000	0.991	0.008
H48.8 Other disorders of optic nerve and visual pathways in diseases classified elsewhere	0.008	0.992	0.000
H48.1 Retrobulbar neuritis in diseases classified elsewhere	0.008	0.992	0.000
H48.0 Optic atrophy in diseases classified elsewhere	0.008	0.992	0.000
H60.4 Cholesteatoma of external ear	0.000	0.992	0.008
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.008	0.992	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.008	0.992	0.000
Z96.2 Presence of otological and audiological implants	0.008	0.992	0.000
G97.8 Other postprocedural disorders of nervous system	0.008	0.992	0.000
H60.3 Other infective otitis externa	0.000	0.992	0.008
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.008	0.992	0.000
K41.1 Bilateral femoral hernia, with gangrene	0.008	0.992	0.000
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.008	0.992	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.992	0.008
C78.2 Secondary malignant neoplasm of pleura	0.008	0.992	0.000
J92 Pleural plaque	0.008	0.992	0.000
G91.1 Obstructive hydrocephalus	0.008	0.992	0.000
J92.9 Pleural plaque without asbestos	0.008	0.992	0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.008	0.992	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.008	0.992	0.000
H50.1 Divergent concomitant strabismus	0.008	0.992	0.000
J92.0 Pleural plaque with presence of asbestos	0.008	0.992	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.007	0.993	0.000
J90-J94 Other diseases of pleura	0.007	0.993	0.000
H60.0 Abscess of external ear	0.000	0.993	0.007
H50.5 Heterophoria	0.007	0.993	0.000
H50.0 Convergent concomitant strabismus	0.007	0.993	0.000
Chapter XXI Factors influencing health status and contact with health services	0.007	0.993	0.000
E65 Localised adiposity	0.007	0.993	0.000
H60.5 Acute otitis externa, non-infective	0.000	0.993	0.007
K90.8 Other intestinal malabsorption	0.000	0.993	0.007
E67 Other hyperalimentation	0.007	0.993	0.000
E68 Sequelae of hyperalimentation	0.007	0.993	0.000
H47.3 Other disorders of optic disk	0.007	0.993	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.007	0.993	0.000
H50.4 Other and unspecified heterotropia	0.007	0.993	0.000
K90.3 Pancreatic steatorrhoea	0.000	0.993	0.007
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.993	0.007
K90.1 Tropical sprue	0.000	0.993	0.007
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.007	0.993	0.000
J41.1 Mucopurulent chronic bronchitis	0.007	0.993	0.000
H42 Glaucoma in diseases classified elsewhere	0.007	0.993	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.007	0.993	0.000
H51 Other disorders of binocular movement	0.007	0.993	0.000
Z57 Occupational exposure to risk-factors	0.007	0.993	0.000
Z87 Personal history of other diseases and conditions	0.007	0.993	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.000	0.993	0.006
H50.6 Mechanical strabismus	0.006	0.994	0.000
H50.3 Intermittent heterotropia	0.006	0.994	0.000
J43 Emphysema	0.006	0.994	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.006	0.994	0.000
H60.9 Otitis externa, unspecified	0.000	0.994	0.006
Z96.8 Presence of other specified functional implants	0.006	0.994	0.000
H53-H54 Visual disturbances and blindness	0.006	0.994	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.006	0.994	0.000
G91 Hydrocephalus	0.006	0.994	0.000
Z57.3 Occupational exposure to other air contaminants	0.006	0.994	0.000
Z57.2 Occupational exposure to dust	0.006	0.994	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.006	0.994	0.000
H50.8 Other specified strabismus	0.006	0.994	0.000
H50.9 Strabismus, unspecified	0.006	0.994	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.994	0.006
J93 Pneumothorax	0.006	0.994	0.000
E21.3 Hyperparathyroidism, unspecified	0.006	0.994	0.000
Z96.7 Presence of other bone and tendon implants	0.006	0.994	0.000
H25-H28 Disorders of lens	0.006	0.994	0.000
J94 Other pleural conditions	0.006	0.994	0.000
H50.2 Vertical strabismus	0.005	0.994	0.000
J41.0 Simple chronic bronchitis	0.005	0.994	0.000
T93 Sequelae of injuries of lower limb	0.006	0.994	0.000
G90-G99 Other disorders of the nervous system	0.005	0.995	0.000
Z58 Problems related to physical environment	0.005	0.995	0.000
H55-H59 Other disorders of eye and adnexa	0.005	0.995	0.000
E67.8 Other specified hyperalimentation	0.005	0.995	0.000
E67.3 Hypervitaminosis D	0.005	0.995	0.000
E67.2 Megavitamin-B6 syndrome	0.005	0.995	0.000
E67.1 Hypercarotenaemia	0.005	0.995	0.000
E67.0 Hypervitaminosis A	0.005	0.995	0.000
E23.0 Hypopituitarism	0.005	0.995	0.000
H43-H45 Disorders of vitreous body and globe	0.005	0.995	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.005	0.995	0.000
Z61 Problems related to negative life events in childhood	0.005	0.995	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.005	0.995	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.005	0.995	0.000
Z72.0 Tobacco use	0.005	0.995	0.000
G90 Disorders of autonomic nervous system	0.005	0.995	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.005	0.995	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.005	0.995	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.005	0.995	0.000
M79.54 Residual foreign body in soft tissue (Hand)	0.005	0.995	0.000
H51.9 Disorder of binocular movement, unspecified	0.005	0.995	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations