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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs501220
log Bayes Factor = 90.8209
Chromosome 6   position 25,873,025  (GRCh37) Explore rs501220 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
D64.9 Anaemia, unspecified
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
D64 Other anaemias
1.000 0.000 0.000
M20-M25 Other joint disorders
0.999 0.001 0.000
D60-D64 Aplastic and other anaemias
0.999 0.001 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.999 0.001 0.000
D50-D53 Nutritional anaemias
0.999 0.001 0.000
E05.9 Thyrotoxicosis, unspecified
0.998 0.002 0.000
D50 Iron deficiency anaemia
0.998 0.002 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.997 0.003 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.997 0.003 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.997 0.003 0.000
C43 Malignant melanoma of skin
0.996 0.004 0.000
D50.9 Iron deficiency anaemia, unspecified
0.996 0.004 0.000
E16 Other disorders of pancreatic internal secretion
0.994 0.006 0.000
E16.2 Hypoglycaemia, unspecified
0.993 0.007 0.000
Chapter V Mental and behavioural disorders
0.992 0.008 0.000
M10 Gout
0.992 0.008 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.991 0.009 0.000
E20-E35 Disorders of other endocrine glands
0.990 0.010 0.000
M35 Other systemic involvement of connective tissue
0.990 0.010 0.000
E70-E90 Metabolic disorders
0.988 0.012 0.000
M24 Other specific joint derangements
0.987 0.013 0.000
M06 Other rheumatoid arthritis
0.987 0.013 0.000
M35.0 Sicca syndrome [Sjogren]
0.986 0.014 0.000
Chapter VII Diseases of the eye and adnexa
0.982 0.018 0.000
M06.9 Rheumatoid arthritis, unspecified
0.982 0.018 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.980 0.020 0.000
C15-C26 Malignant neoplasms of digestive organs
0.979 0.021 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.978 0.022 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.978 0.022 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.975 0.025 0.000
M10.9 Gout, unspecified
0.975 0.025 0.000
H30-H36 Disorders of choroid and retina
0.975 0.025 0.000
E10.3 With ophthalmic complications
0.967 0.033 0.000
M24.1 Other articular cartilage disorders
0.965 0.035 0.000
D80-D89 Certain disorders involving the immune mechanism
0.963 0.037 0.000
F03 Unspecified dementia
0.962 0.038 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.962 0.038 0.000
F05.9 Delirium, unspecified
0.961 0.039 0.000
E83 Disorders of mineral metabolism
0.953 0.039 0.008
D50.8 Other iron deficiency anaemias
0.958 0.042 0.000
C18 Malignant neoplasm of colon
0.957 0.043 0.000
C43.5 Malignant melanoma of trunk
0.955 0.045 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.950 0.050 0.000
E27 Other disorders of adrenal gland
0.948 0.052 0.000
C18.9 Colon, unspecified
0.946 0.054 0.000
M07 Psoriatic and enteropathic arthropathies
0.942 0.058 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.938 0.062 0.000
E83.5 Disorders of calcium metabolism
0.938 0.062 0.000
E10.1 With ketoacidosis
0.937 0.063 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.934 0.066 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.934 0.066 0.000
E27.1 Primary adrenocortical insufficiency
0.930 0.070 0.000
D86 Sarcoidosis
0.930 0.070 0.000
C25 Malignant neoplasm of pancreas
0.927 0.073 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.924 0.076 0.000
C34 Malignant neoplasm of bronchus and lung
0.923 0.077 0.000
M15-M19 Arthrosis
0.922 0.078 0.000
H35 Other retinal disorders
0.920 0.080 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.920 0.080 0.000
H53-H54 Visual disturbances and blindness
0.919 0.081 0.000
M17 Gonarthrosis [arthrosis of knee]
0.914 0.086 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.913 0.087 0.000
C43.9 Malignant melanoma of skin, unspecified
0.912 0.088 0.000
E23 Hypofunction and other disorders of pituitary gland
0.910 0.090 0.000
K90 Intestinal malabsorption
0.908 0.092 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.901 0.099 0.000
H54 Blindness and low vision
0.901 0.099 0.000
M07.3 Other psoriatic arthropathies
0.901 0.099 0.000
M10.99 Gout, unspecified (Site unspecified)
0.899 0.101 0.000
M10.90 Gout, unspecified (Multiple sites)
0.897 0.103 0.000
M10.0 Idiopathic gout
0.897 0.103 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.104 0.896
E78.6 Lipoprotein deficiency
0.895 0.105 0.000
H36 Retinal disorders in diseases classified elsewhere
0.892 0.108 0.000
M34 Systemic sclerosis
0.888 0.112 0.000
F02 Dementia in other diseases classified elsewhere
0.881 0.119 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.879 0.121 0.000
H43-H45 Disorders of vitreous body and globe
0.878 0.122 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.878 0.122 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.877 0.123 0.000
C34.3 Lower lobe, bronchus or lung
0.876 0.124 0.000
E78.5 Hyperlipidaemia, unspecified
0.875 0.125 0.000
M22 Disorders of patella
0.873 0.127 0.000
M17.9 Gonarthrosis, unspecified
0.872 0.128 0.000
H31 Other disorders of choroid
0.872 0.128 0.000
M65-M68 Disorders of synovium and tendon
0.870 0.130 0.000
D86.9 Sarcoidosis, unspecified
0.870 0.130 0.000
E21.3 Hyperparathyroidism, unspecified
0.870 0.130 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.869 0.131 0.000
H34 Retinal vascular occlusions
0.868 0.132 0.000
C23 Malignant neoplasm of gallbladder
0.862 0.138 0.000
F99-F99 Unspecified mental disorder
0.859 0.141 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.859 0.141 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.856 0.144 0.000
C34.0 Main bronchus
0.853 0.147 0.000
H35.8 Other specified retinal disorders
0.848 0.152 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.847 0.153 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.842 0.158 0.000
E10.2 With renal complications
0.842 0.158 0.000
C25.9 Pancreas, unspecified
0.839 0.161 0.000
E14 Unspecified diabetes mellitus
0.839 0.161 0.000
E21.0 Primary hyperparathyroidism
0.839 0.161 0.000
C43.4 Malignant melanoma of scalp and neck
0.837 0.163 0.000
C18.6 Descending colon
0.837 0.163 0.000
M11 Other crystal arthropathies
0.837 0.163 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.836 0.164 0.000
C81 Hodgkin's disease
0.835 0.165 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.834 0.166 0.000
H43 Disorders of vitreous body
0.834 0.166 0.000
E78.1 Pure hyperglyceridaemia
0.834 0.166 0.000
H36.0 Diabetic retinopathy
0.834 0.166 0.000
E23.2 Diabetes insipidus
0.832 0.168 0.000
H46 Optic neuritis
0.831 0.169 0.000
M00-M03 Infectious arthropathies
0.830 0.170 0.000
M10.07 Idiopathic gout (Ankle and foot)
0.829 0.171 0.000
H54.0 Blindness, both eyes
0.829 0.171 0.000
M60-M63 Disorders of muscles
0.826 0.174 0.000
E10.5 With peripheral circulatory complications
0.826 0.174 0.000
E88 Other metabolic disorders
0.826 0.174 0.000
M10.94 Gout, unspecified (Hand)
0.825 0.175 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.823 0.177 0.000
C83.3 Large cell (diffuse)
0.819 0.181 0.000
M86-M90 Other osteopathies
0.810 0.190 0.000
C82.2 Large cell, follicular
0.810 0.190 0.000
F60-F69 Disorders of adult personality and behaviour
0.807 0.193 0.000
E78.2 Mixed hyperlipidaemia
0.807 0.193 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.807 0.193 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.806 0.194 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.805 0.195 0.000
M17.1 Other primary gonarthrosis
0.804 0.196 0.000
D50.1 Sideropenic dysphagia
0.801 0.199 0.000
D86.3 Sarcoidosis of skin
0.800 0.200 0.000
C22.9 Liver, unspecified
0.799 0.201 0.000
M10.96 Gout, unspecified (Lower leg)
0.797 0.203 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.795 0.205 0.000
F02.0 Dementia in Pick's disease
0.795 0.205 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.793 0.207 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.792 0.208 0.000
H34.2 Other retinal artery occlusions
0.790 0.210 0.000
H54.4 Blindness, one eye
0.790 0.210 0.000
E10.8 With unspecified complications
0.788 0.212 0.000
J98 Other respiratory disorders
0.788 0.212 0.000
F80-F89 Disorders of psychological development
0.787 0.213 0.000
J95-J99 Other diseases of the respiratory system
0.787 0.213 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.785 0.215 0.000
C25.2 Tail of pancreas
0.785 0.215 0.000
Chapter X Diseases of the respiratory system
0.784 0.216 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.782 0.218 0.000
H43.1 Vitreous haemorrhage
0.782 0.218 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.781 0.219 0.000
H35.4 Peripheral retinal degeneration
0.780 0.220 0.000
D53 Other nutritional anaemias
0.778 0.222 0.000
E73 Lactose intolerance
0.778 0.222 0.000
M06.4 Inflammatory polyarthropathy
0.777 0.223 0.000
M22.3 Other derangements of patella
0.777 0.223 0.000
F01 Vascular dementia
0.776 0.224 0.000
C85.1 B-cell lymphoma, unspecified
0.775 0.225 0.000
H35.0 Background retinopathy and retinal vascular changes
0.775 0.225 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.774 0.226 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.773 0.227 0.000
C82.0 Small cleaved cell, follicular
0.773 0.227 0.000
E84 Cystic fibrosis
0.771 0.229 0.000
F05.8 Other delirium
0.768 0.232 0.000
H30 Chorioretinal inflammation
0.768 0.232 0.000
M32 Systemic lupus erythematosus
0.767 0.233 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.767 0.233 0.000
M35.7 Hypermobility syndrome
0.766 0.234 0.000
E23.7 Disorder of pituitary gland, unspecified
0.765 0.235 0.000
F99 Mental disorder, not otherwise specified
0.764 0.236 0.000
C07 Malignant neoplasm of parotid gland
0.763 0.237 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.762 0.238 0.000
C34.2 Middle lobe, bronchus or lung
0.761 0.239 0.000
C95 Leukaemia of unspecified cell type
0.759 0.241 0.000
H35.7 Separation of retinal layers
0.759 0.241 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.758 0.242 0.000
C18.2 Ascending colon
0.757 0.243 0.000
C38.4 Pleura
0.756 0.243 0.000
E10.6 With other specified complications
0.756 0.244 0.000
M17.3 Other posttraumatic gonarthrosis
0.756 0.244 0.000
M14 Arthropathies in other diseases classified elsewhere
0.756 0.244 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.755 0.245 0.000
D55-D59 Haemolytic anaemias
0.754 0.246 0.000
D64.8 Other specified anaemias
0.753 0.247 0.000
J98.4 Other disorders of lung
0.753 0.247 0.000
H54.6 Unqualified visual loss, one eye
0.750 0.250 0.000
M24.0 Loose body in joint
0.749 0.251 0.000
L20-L30 Dermatitis and eczema
0.749 0.251 0.000
E78.4 Other hyperlipidaemia
0.749 0.251 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.747 0.253 0.000
C18.5 Splenic flexure
0.746 0.254 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.745 0.255 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.744 0.255 0.000
E05.8 Other thyrotoxicosis
0.744 0.256 0.000
M21 Other acquired deformities of limbs
0.744 0.256 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.742 0.258 0.000
M33 Dermatopolymyositis
0.741 0.259 0.000
E24 Cushing's syndrome
0.740 0.259 0.000
E50-E64 Other nutritional deficiencies
0.740 0.260 0.000
E20 Hypoparathyroidism
0.739 0.261 0.000
M34.8 Other forms of systemic sclerosis
0.738 0.262 0.000
E34 Other endocrine disorders
0.738 0.262 0.000
H31.0 Chorioretinal scars
0.736 0.264 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.734 0.266 0.000
E83.4 Disorders of magnesium metabolism
0.730 0.267 0.002
M31 Other necrotising vasculopathies
0.732 0.268 0.000
C93 Monocytic leukaemia
0.731 0.269 0.000
M17.0 Primary gonarthrosis, bilateral
0.731 0.269 0.000
D86.0 Sarcoidosis of lung
0.731 0.269 0.000
M66 Spontaneous rupture of synovium and tendon
0.730 0.269 0.000
M15 Polyarthrosis
0.727 0.273 0.000
H35.2 Other proliferative retinopathy
0.727 0.273 0.000
H47.2 Optic atrophy
0.723 0.277 0.000
D84 Other immunodeficiencies
0.722 0.278 0.000
C25.3 Pancreatic duct
0.720 0.280 0.000
M67 Other disorders of synovium and tendon
0.719 0.281 0.000
D86.8 Sarcoidosis of other and combined sites
0.718 0.282 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.3 Other sideroblastic anaemias
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.716 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.716 0.283 0.000
E23.6 Other disorders of pituitary gland
0.716 0.284 0.000
E05.5 Thyroid crisis or storm
0.716 0.284 0.000
E05.4 Thyrotoxicosis factitia
0.716 0.284 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.716 0.284 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.716 0.284 0.000
M34.1 CR(E)ST syndrome
0.716 0.284 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.715 0.285 0.000
C94 Other leukaemias of specified cell type
0.715 0.285 0.000
C86 Other specified types of T/NK-cell lymphoma
0.715 0.285 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.715 0.285 0.000
E15 Nondiabetic hypoglycaemic coma
0.715 0.285 0.000
C43.8 Overlapping malignant melanoma of skin
0.714 0.286 0.000
C43.0 Malignant melanoma of lip
0.714 0.286 0.000
M86 Osteomyelitis
0.714 0.286 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.713 0.287 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.713 0.287 0.000
E16.4 Abnormal secretion of gastrin
0.713 0.287 0.000
E16.3 Increased secretion of glucagon
0.713 0.287 0.000
C04 Malignant neoplasm of floor of mouth
0.712 0.288 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.711 0.288 0.000
M10.4 Other secondary gout
0.711 0.289 0.000
M10.3 Gout due to impairment of renal function
0.711 0.289 0.000
M10.2 Drug-induced gout
0.711 0.289 0.000
M10.1 Lead-induced gout
0.711 0.289 0.000
F09 Unspecified organic or symptomatic mental disorder
0.711 0.289 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.711 0.289 0.000
M11.2 Other chondrocalcinosis
0.711 0.289 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.710 0.290 0.000
L27 Dermatitis due to substances taken internally
0.710 0.290 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.710 0.290 0.000
E32 Diseases of thymus
0.710 0.290 0.000
E31 Polyglandular dysfunction
0.710 0.290 0.000
E30 Disorders of puberty, not elsewhere classified
0.710 0.290 0.000
E25 Adrenogenital disorders
0.710 0.290 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.710 0.290 0.000
M35.8 Other specified systemic involvement of connective tissue
0.710 0.290 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.710 0.290 0.000
M35.5 Multifocal fibrosclerosis
0.710 0.290 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.710 0.290 0.000
M35.2 Behcet's disease
0.710 0.290 0.000
K90.9 Intestinal malabsorption, unspecified
0.709 0.291 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.709 0.291 0.000
D83 Common variable immunodeficiency
0.709 0.291 0.000
M00 Pyogenic arthritis
0.708 0.292 0.000
E79 Disorders of purine and pyrimidine metabolism
0.708 0.292 0.000
E77 Disorders of glycoprotein metabolism
0.708 0.292 0.000
E76 Disorders of glycosaminoglycan metabolism
0.708 0.292 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.708 0.292 0.000
E72 Other disorders of amino-acid metabolism
0.708 0.292 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.708 0.292 0.000
E70 Disorders of aromatic amino-acid metabolism
0.708 0.292 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.708 0.292 0.000
M24.9 Joint derangement, unspecified
0.708 0.292 0.000
M06.8 Other specified rheumatoid arthritis
0.708 0.292 0.000
M06.2 Rheumatoid bursitis
0.708 0.292 0.000
M06.1 Adult-onset Still's disease
0.708 0.292 0.000
C25.0 Head of pancreas
0.707 0.293 0.000
H54.7 Unspecified visual loss
0.706 0.294 0.000
M24.7 Protrusio acetabuli
0.706 0.294 0.000
E74 Other disorders of carbohydrate metabolism
0.706 0.294 0.000
E10.0 With coma
0.704 0.296 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.703 0.297 0.000
E78.3 Hyperchylomicronaemia
0.703 0.297 0.000
D52 Folate deficiency anaemia
0.703 0.297 0.000
M62 Other disorders of muscle
0.702 0.298 0.000
K90-K93 Other diseases of the digestive system
0.701 0.298 0.000
C82.6 Cutaneous follicle centre lymphoma
0.701 0.299 0.000
C82.5 Diffuse follicle centre lymphoma
0.701 0.299 0.000
C82.4 Follicular lymphoma grade IIIb
0.701 0.299 0.000
C82.3 Follicular lymphoma grade IIIa
0.701 0.299 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.700 0.300 0.000
E14.1 With ketoacidosis
0.700 0.300 0.000
F05.1 Delirium superimposed on dementia
0.699 0.301 0.000
M10.98 Gout, unspecified (Other)
0.699 0.301 0.000
M10.95 Gout, unspecified (Pelvic region and thigh)
0.699 0.301 0.000
M10.91 Gout, unspecified (Shoulder region)
0.699 0.301 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.699 0.301 0.000
C22.1 Intrahepatic bile duct carcinoma
0.699 0.301 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.699 0.301 0.000
E27.2 Addisonian crisis
0.698 0.302 0.000
M23 Internal derangement of knee
0.698 0.302 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.696 0.304 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.695 0.305 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.695 0.305 0.000
M21.0 Valgus deformity, not elsewhere classified
0.694 0.306 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.694 0.306 0.000
M17.5 Other secondary gonarthrosis
0.694 0.306 0.000
H31.9 Disorder of choroid, unspecified
0.694 0.306 0.000
J90-J94 Other diseases of pleura
0.693 0.307 0.000
M34.9 Systemic sclerosis, unspecified
0.693 0.307 0.000
H18 Other disorders of cornea
0.692 0.308 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.692 0.308 0.000
M24.18 Other articular cartilage disorders (Other)
0.692 0.308 0.000
M24.14 Other articular cartilage disorders (Hand)
0.692 0.308 0.000
M24.12 Other articular cartilage disorders (Upper arm)
0.692 0.308 0.000
M24.10 Other articular cartilage disorders (Multiple sites)
0.692 0.308 0.000
C03 Malignant neoplasm of gum
0.691 0.308 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.691 0.309 0.000
M13 Other arthritis
0.691 0.309 0.000
D82 Immunodeficiency associated with other major defects
0.691 0.309 0.000
D81 Combined immunodeficiencies
0.691 0.309 0.000
C18.3 Hepatic flexure
0.690 0.310 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.689 0.311 0.000
C31 Malignant neoplasm of accessory sinuses
0.689 0.311 0.000
C37 Malignant neoplasm of thymus
0.689 0.311 0.000
C33 Malignant neoplasm of trachea
0.689 0.311 0.000
C13 Malignant neoplasm of hypopharynx
0.689 0.311 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.683 0.311 0.006
E83.8 Other disorders of mineral metabolism
0.683 0.311 0.006
E83.2 Disorders of zinc metabolism
0.683 0.311 0.006
E83.0 Disorders of copper metabolism
0.683 0.311 0.006
H31.8 Other specified disorders of choroid
0.688 0.312 0.000
E13 Other specified diabetes mellitus
0.688 0.312 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.686 0.314 0.000
M22.8 Other disorders of patella
0.686 0.314 0.000
C18.4 Transverse colon
0.686 0.314 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.685 0.315 0.000
J98.1 Pulmonary collapse
0.685 0.315 0.000
E14.5 With peripheral circulatory complications
0.685 0.315 0.000
C17 Malignant neoplasm of small intestine
0.684 0.316 0.000
C83.7 Burkitt's tumour
0.684 0.316 0.000
F05.0 Delirium not superimposed on dementia, so described
0.684 0.316 0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)
0.683 0.317 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.683 0.317 0.000
H35.3 Degeneration of macula and posterior pole
0.681 0.319 0.000
D80 Immunodeficiency with predominantly antibody defects
0.680 0.320 0.000
F69 Unspecified disorder of adult personality and behaviour
0.680 0.320 0.000
E27.5 Adrenomedullary hyperfunction
0.680 0.320 0.000
E27.0 Other adrenocortical overactivity
0.680 0.320 0.000
J92 Pleural plaque
0.679 0.321 0.000
H43.2 Crystalline deposits in vitreous body
0.679 0.321 0.000
M10.92 Gout, unspecified (Upper arm)
0.678 0.322 0.000
F00 Dementia in Alzheimer's disease
0.677 0.323 0.000
E16.1 Other hypoglycaemia
0.676 0.323 0.000
M24.5 Contracture of joint
0.676 0.323 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.677 0.323 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.676 0.324 0.000
M07.6 Other enteropathic arthropathies
0.675 0.325 0.000
M07.5 Arthropathy in ulcerative colitis
0.675 0.325 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.675 0.325 0.000
M07.2 Psoriatic spondylitis
0.675 0.325 0.000
M07.1 Arthritis mutilans
0.675 0.325 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.675 0.325 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.675 0.325 0.000
H43.3 Other vitreous opacities
0.674 0.326 0.000
M89 Other disorders of bone
0.673 0.327 0.000
Chapter XI Diseases of the digestive system
0.672 0.327 0.001
C30 Malignant neoplasm of nasal cavity and middle ear
0.673 0.327 0.000
E14.6 With other specified complications
0.673 0.327 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.671 0.329 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.670 0.330 0.000
H17 Corneal scars and opacities
0.670 0.330 0.000
C84.5 Other and unspecified T-cell lymphomas
0.670 0.330 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.670 0.330 0.000
E21.4 Other specified disorders of parathyroid gland
0.670 0.330 0.000
E21.2 Other hyperparathyroidism
0.670 0.330 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.670 0.330 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.670 0.330 0.000
C85.0 Lymphosarcoma
0.670 0.330 0.000
L40-L45 Papulosquamous disorders
0.667 0.333 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.667 0.333 0.000
F70-F79 Mental retardation
0.666 0.334 0.000
L30 Other dermatitis
0.666 0.334 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.666 0.334 0.000
C01 Malignant neoplasm of base of tongue
0.666 0.334 0.000
C25.8 Overlapping lesion of pancreas
0.665 0.335 0.000
C25.7 Other parts of pancreas
0.665 0.335 0.000
C25.4 Endocrine pancreas
0.665 0.335 0.000
Q50-Q56 Congenital malformations of genital organs
0.665 0.335 0.000
C83.1 Small cleaved cell (diffuse)
0.664 0.336 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.662 0.337 0.000
C34.8 Overlapping lesion of bronchus and lung
0.662 0.338 0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)
0.662 0.338 0.000
H35.1 Retinopathy of prematurity
0.660 0.340 0.000
H54.9 Unspecified visual impairment (binocular)
0.660 0.340 0.000
L50-L54 Urticaria and erythema
0.659 0.341 0.000
E14.3 With ophthalmic complications
0.659 0.341 0.000
J92.0 Pleural plaque with presence of asbestos
0.657 0.343 0.000
M24.6 Ankylosis of joint
0.656 0.344 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.656 0.344 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.655 0.345 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.655 0.345 0.000
H54.2 Low vision, both eyes
0.655 0.345 0.000
C81.0 Lymphocytic predominance
0.654 0.346 0.000
C81.9 Hodgkin's disease, unspecified
0.654 0.346 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.654 0.346 0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)
0.653 0.347 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.653 0.347 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.652 0.347 0.000
E23.1 Drug-induced hypopituitarism
0.652 0.347 0.000
Q27 Other congenital malformations of peripheral vascular system
0.653 0.347 0.000
F02.8 Dementia in other specified diseases classified elsewhere
0.652 0.348 0.000
E78.8 Other disorders of lipoprotein metabolism
0.652 0.348 0.000
K90.3 Pancreatic steatorrhoea
0.651 0.349 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.651 0.349 0.000
K90.1 Tropical sprue
0.651 0.349 0.000
H34.1 Central retinal artery occlusion
0.650 0.350 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.649 0.351 0.000
M22.0 Recurrent dislocation of patella
0.648 0.352 0.000
C00 Malignant neoplasm of lip
0.646 0.354 0.000
H54.5 Low vision, one eye
0.646 0.354 0.000
H54.3 Unqualified visual loss, both eyes
0.646 0.354 0.000
H54.1 Blindness, one eye, low vision, other eye
0.646 0.354 0.000
M07.38 Other psoriatic arthropathies (Other)
0.646 0.354 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.646 0.354 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.646 0.354 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.646 0.354 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.646 0.354 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.646 0.354 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.646 0.354 0.000
C05 Malignant neoplasm of palate
0.646 0.354 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.645 0.355 0.000
M23.4 Loose body in knee
0.645 0.355 0.000
M10.09 Idiopathic gout (Site unspecified)
0.643 0.357 0.000
M10.08 Idiopathic gout (Other)
0.643 0.357 0.000
M10.06 Idiopathic gout (Lower leg)
0.643 0.357 0.000
M10.05 Idiopathic gout (Pelvic region and thigh)
0.643 0.357 0.000
M10.04 Idiopathic gout (Hand)
0.643 0.357 0.000
M10.03 Idiopathic gout (Forearm)
0.643 0.357 0.000
M10.02 Idiopathic gout (Upper arm)
0.643 0.357 0.000
M10.01 Idiopathic gout (Shoulder region)
0.643 0.357 0.000
M10.00 Idiopathic gout (Multiple sites)
0.643 0.357 0.000
M66.3 Spontaneous rupture of flexor tendons
0.642 0.358 0.000
C84.0 Mycosis fungoides
0.641 0.359 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.641 0.359 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.641 0.359 0.000
M24.2 Disorder of ligament
0.640 0.360 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.640 0.360 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.640 0.360 0.000
K90.8 Other intestinal malabsorption
0.639 0.360 0.000
M10.93 Gout, unspecified (Forearm)
0.639 0.361 0.000
M06.3 Rheumatoid nodule
0.639 0.361 0.000
F81 Specific developmental disorders of scholastic skills
0.639 0.361 0.000
L23 Allergic contact dermatitis
0.638 0.362 0.000
C11 Malignant neoplasm of nasopharynx
0.638 0.362 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.638 0.362 0.000
H35.5 Hereditary retinal dystrophy
0.638 0.362 0.000
C18.8 Overlapping lesion of colon
0.638 0.362 0.000
M22.2 Patellofemoral disorders
0.637 0.362 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.637 0.363 0.000
M34.0 Progressive systemic sclerosis
0.637 0.363 0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)
0.636 0.364 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.635 0.365 0.000
Q28 Other congenital malformations of circulatory system
0.635 0.365 0.000
F02.3 Dementia in Parkinson's disease
0.635 0.365 0.000
C15 Malignant neoplasm of oesophagus
0.635 0.365 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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