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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs5024431
log Bayes Factor = 75.8398
Chromosome 6   position 32,684,344  (GRCh37) Explore rs5024431 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C44.3 Skin of other and unspecified parts of face
0.000 0.000 1.000
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
E10.1 With ketoacidosis
1.000 0.000 0.000
C44 Other malignant neoplasms of skin
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
G35 Multiple sclerosis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
C44.7 Skin of lower limb, including hip
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
1.000 0.000 0.000
E10.4 With neurological complications
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
1.000 0.000 0.000
E14.9 Without complications
0.998 0.002 0.000
C44.6 Skin of upper limb, including shoulder
0.000 0.003 0.997
E14.3 With ophthalmic complications
0.997 0.003 0.000
C44.4 Skin of scalp and neck
0.000 0.004 0.996
E16 Other disorders of pancreatic internal secretion
0.994 0.006 0.000
H36.0 Diabetic retinopathy
0.993 0.007 0.000
E11 Non-insulin-dependent diabetes mellitus
0.993 0.007 0.000
E11.9 Without complications
0.992 0.008 0.000
E10.5 With peripheral circulatory complications
0.988 0.012 0.000
K51.9 Ulcerative colitis, unspecified
0.000 0.013 0.987
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.985 0.015 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.979 0.021 0.000
C44.2 Skin of ear and external auricular canal
0.000 0.055 0.945
K51 Ulcerative colitis
0.000 0.062 0.938
E10.8 With unspecified complications
0.931 0.069 0.000
E10.2 With renal complications
0.919 0.081 0.000
C44.5 Skin of trunk
0.000 0.095 0.905
E40-E46 Malnutrition
0.875 0.125 0.000
K51.4 Pseudopolyposis of colon
0.000 0.128 0.872
C44.0 Skin of lip
0.000 0.131 0.869
E11.1 With ketoacidosis
0.846 0.154 0.000
E16.1 Other hypoglycaemia
0.845 0.155 0.000
E10.0 With coma
0.844 0.156 0.000
Z93.2 Ileostomy status
0.000 0.169 0.831
E10.6 With other specified complications
0.828 0.172 0.000
E14.6 With other specified complications
0.828 0.172 0.000
E14.8 With unspecified complications
0.813 0.187 0.000
E46 Unspecified protein-energy malnutrition
0.801 0.199 0.000
E13 Other specified diabetes mellitus
0.797 0.203 0.000
K51.2 Ulcerative (chronic) proctitis
0.000 0.204 0.796
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.210 0.790
E14.2 Withrenal complications
0.768 0.232 0.000
E11.3 With ophthalmic complications
0.758 0.242 0.000
E10.7 With multiple complications
0.757 0.243 0.000
E11.0 With coma
0.745 0.255 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.000 0.265 0.734
K51.5 Mucosal proctocolitis
0.000 0.271 0.729
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.281 0.719
E16.0 Drug-induced hypoglycaemia without coma
0.719 0.281 0.000
C44.8 Overlapping lesion of skin
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E14.7 With multiple complications
0.717 0.283 0.000
E14.0 With coma
0.717 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.712 0.288 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.712 0.288 0.000
E16.4 Abnormal secretion of gastrin
0.712 0.288 0.000
E16.3 Increased secretion of glucagon
0.712 0.288 0.000
E11.7 With multiple complications
0.712 0.288 0.000
E11.6 With other specified complications
0.710 0.290 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.292 0.708
E14.5 With peripheral circulatory complications
0.706 0.293 0.000
E15 Nondiabetic hypoglycaemic coma
0.706 0.294 0.000
E50-E64 Other nutritional deficiencies
0.702 0.298 0.000
K51.8 Other ulcerative colitis
0.000 0.312 0.688
E13.9 Without complications
0.638 0.362 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.627 0.372 0.000
E45 Retarded development following protein-energy malnutrition
0.627 0.372 0.000
E43 Unspecified severe protein-energy malnutrition
0.627 0.372 0.000
E42 Marasmic kwashiorkor
0.627 0.372 0.000
E41 Nutritional marasmus
0.627 0.372 0.000
E40 Kwashiorkor
0.627 0.372 0.000
E61 Deficiency of other nutrient elements
0.616 0.384 0.000
E14.1 With ketoacidosis
0.603 0.397 0.000
E13.3 With ophthalmic complications
0.590 0.410 0.000
E11.4 With neurological complications
0.580 0.420 0.000
E14.4 With neurological complications
0.571 0.428 0.000
E13.8 With unspecified complications
0.571 0.429 0.000
E13.7 With multiple complications
0.571 0.429 0.000
E13.6 With other specified complications
0.571 0.429 0.000
E13.5 With peripheral circulatory complications
0.571 0.429 0.000
E13.4 With neurological complications
0.571 0.429 0.000
E13.2 With renal complications
0.571 0.429 0.000
E13.1 With ketoacidosis
0.571 0.429 0.000
E13.0 With coma
0.571 0.429 0.000
E54 Ascorbic acid deficiency
0.567 0.433 0.000
E11.8 With unspecified complications
0.566 0.434 0.000
E61.1 Iron deficiency
0.562 0.438 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E65-E68 Obesity and other hyperalimentation
0.513 0.487 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.000 0.491 0.509
E58 Dietary calcium deficiency
0.508 0.492 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.503 0.496 0.000
E63 Other nutritional deficiencies
0.503 0.496 0.000
E56 Other vitamin deficiencies
0.503 0.496 0.000
E51 Thiamine deficiency
0.503 0.496 0.000
E50 Vitamin A deficiency
0.503 0.496 0.000
E60 Dietary zinc deficiency
0.503 0.496 0.000
E59 Dietary selenium deficiency
0.503 0.496 0.000
E52 Niacin deficiency [pellagra]
0.503 0.496 0.000
E11.2 With renal complications
0.453 0.547 0.000
E44.1 Mild protein-energy malnutrition
0.450 0.550 0.000
E44.0 Moderate protein-energy malnutrition
0.450 0.550 0.000
E11.5 With peripheral circulatory complications
0.445 0.555 0.000
E61.9 Deficiency of nutrient element, unspecified
0.442 0.558 0.000
E61.8 Deficiency of other specified nutrient elements
0.442 0.558 0.000
E61.7 Deficiency of multiple nutrient elements
0.442 0.558 0.000
E61.6 Vanadium deficiency
0.442 0.558 0.000
E61.5 Molybdenum deficiency
0.442 0.558 0.000
E61.4 Chromium deficiency
0.442 0.558 0.000
E61.3 Manganese deficiency
0.442 0.558 0.000
E61.0 Copper deficiency
0.442 0.558 0.000
H36 Retinal disorders in diseases classified elsewhere
0.432 0.568 0.000
E61.2 Magnesium deficiency
0.417 0.583 0.000
C43 Malignant melanoma of skin
0.000 0.591 0.409
L57.0 Actinic keratosis
0.000 0.592 0.408
E65 Localised adiposity
0.388 0.612 0.000
Z93 Artificial opening status
0.000 0.630 0.370
E67 Other hyperalimentation
0.368 0.632 0.000
E68 Sequelae of hyperalimentation
0.368 0.632 0.000
E50.9 Vitamin A deficiency, unspecified
0.361 0.639 0.000
E50.8 Other manifestations of vitamin A deficiency
0.361 0.639 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.361 0.639 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.361 0.639 0.000
E50.5 Vitamin A deficiency with night blindness
0.361 0.639 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.361 0.639 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.361 0.639 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.361 0.639 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.361 0.639 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.361 0.639 0.000
E51.9 Thiamine deficiency, unspecified
0.361 0.639 0.000
E51.8 Other manifestations of thiamine deficiency
0.361 0.639 0.000
E51.2 Wernicke's encephalopathy
0.361 0.639 0.000
E51.1 Beriberi
0.361 0.639 0.000
E56.9 Vitamin deficiency, unspecified
0.361 0.639 0.000
E56.8 Deficiency of other vitamins
0.361 0.639 0.000
E56.1 Deficiency of vitamin K
0.361 0.639 0.000
E56.0 Deficiency of vitamin E
0.361 0.639 0.000
E63.9 Nutritional deficiency, unspecified
0.361 0.639 0.000
E63.8 Other specified nutritional deficiencies
0.361 0.639 0.000
E63.1 Imbalance of constituents of food intake
0.361 0.639 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.361 0.639 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.361 0.639 0.000
E64.8 Sequelae of other nutritional deficiencies
0.361 0.639 0.000
E64.3 Sequelae of rickets
0.361 0.639 0.000
E64.2 Sequelae of vitamin C deficiency
0.361 0.639 0.000
E64.1 Sequelae of vitamin A deficiency
0.361 0.639 0.000
E64.0 Sequelae of protein-energy malnutrition
0.361 0.639 0.000
Z93.5 Cystostomy status
0.000 0.646 0.354
E55 Vitamin D deficiency
0.351 0.649 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.652 0.348
C44.1 Skin of eyelid, including canthus
0.000 0.652 0.348
Z93.0 Tracheostomy status
0.000 0.663 0.337
C43.6 Malignant melanoma of upper limb, including shoulder
0.000 0.664 0.336
C43.4 Malignant melanoma of scalp and neck
0.000 0.667 0.333
N47 Redundant prepuce, phimosis and paraphimosis
0.329 0.671 0.000
E53 Deficiency of other B group vitamins
0.311 0.689 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.309 0.690 0.000
Z93.9 Artificial opening status, unspecified
0.000 0.695 0.305
C43.9 Malignant melanoma of skin, unspecified
0.000 0.702 0.298
Z93.8 Other artificial opening status
0.000 0.705 0.295
C43.8 Overlapping malignant melanoma of skin
0.000 0.706 0.293
C43.0 Malignant melanoma of lip
0.000 0.706 0.293
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.709 0.291
C43.1 Malignant melanoma of eyelid, including canthus
0.000 0.726 0.274
C43.5 Malignant melanoma of trunk
0.000 0.735 0.265
E67.8 Other specified hyperalimentation
0.264 0.736 0.000
E67.3 Hypervitaminosis D
0.264 0.736 0.000
E67.2 Megavitamin-B6 syndrome
0.264 0.736 0.000
E67.1 Hypercarotenaemia
0.264 0.736 0.000
E67.0 Hypervitaminosis A
0.264 0.736 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.000 0.740 0.259
E55.0 Rickets, active
0.252 0.748 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.767 0.233
C43.7 Malignant melanoma of lower limb, including hip
0.000 0.768 0.232
E53.1 Pyridoxine deficiency
0.223 0.777 0.000
E53.0 Riboflavin deficiency
0.223 0.777 0.000
N48 Other disorders of penis
0.202 0.798 0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.802 0.198
N40-N51 Diseases of male genital organs
0.196 0.804 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.000 0.805 0.195
G36 Other acute disseminated demyelination
0.000 0.806 0.194
E53.9 Vitamin B deficiency, unspecified
0.194 0.806 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.192 0.808 0.000
N48.0 Leukoplakia of penis
0.189 0.811 0.000
N49.2 Inflammatory disorders of scrotum
0.189 0.811 0.000
N48.6 Balanitis xerotica obliterans
0.187 0.813 0.000
N48.4 Impotence of organic origin
0.174 0.826 0.000
N48.9 Disorder of penis, unspecified
0.170 0.830 0.000
G37 Other demyelinating diseases of central nervous system
0.000 0.830 0.169
L57.5 Actinic granuloma
0.000 0.833 0.167
L57.3 Poikiloderma of Civatte
0.000 0.833 0.167
L57.2 Cutis rhomboidalis nuchae
0.000 0.833 0.167
L57.1 Actinic reticuloid
0.000 0.833 0.167
N48.2 Other inflammatory disorders of penis
0.163 0.837 0.000
N48.3 Priapism
0.161 0.839 0.000
L57.4 Cutis laxa senilis
0.000 0.841 0.159
N48.1 Balanoposthitis
0.155 0.845 0.000
N49.8 Inflammatory disorders of other specified male genital organs
0.154 0.846 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.154 0.846 0.000
N48.5 Ulcer of penis
0.150 0.850 0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.856 0.144
G36.9 Acute disseminated demyelination, unspecified
0.000 0.860 0.139
G36.8 Other specified acute disseminated demyelination
0.000 0.860 0.139
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.860 0.139
N49.9 Inflammatory disorder of unspecified male genital organ
0.138 0.862 0.000
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.138 0.862 0.000
N49.0 Inflammatory disorders of seminal vesicle
0.138 0.862 0.000
N35.9 Urethral stricture, unspecified
0.136 0.864 0.000
Z93.6 Other artificial openings of urinary tract status
0.000 0.872 0.128
G36.0 Neuromyelitis optica [Devic]
0.000 0.875 0.124
N51.2 Balanitis in diseases classified elsewhere
0.124 0.876 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.876 0.124
E66 Obesity
0.124 0.876 0.000
N46 Male infertility
0.122 0.878 0.000
G37.5 Concentric sclerosis [Balo]
0.000 0.878 0.122
G37.4 Subacute necrotising myelitis
0.000 0.878 0.122
G37.2 Central pontine myelinolysis
0.000 0.878 0.122
G37.1 Central demyelination of corpus callosum
0.000 0.878 0.122
G37.0 Diffuse sclerosis
0.000 0.878 0.122
N44 Torsion of testis
0.121 0.878 0.000
N45 Orchitis and epididymitis
0.120 0.880 0.000
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.110 0.889 0.000
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.110 0.889 0.000
N51.0 Disorders of prostate in diseases classified elsewhere
0.110 0.889 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.890 0.110
E53.8 Deficiency of other specified B group vitamins
0.099 0.901 0.000
E55.9 Vitamin D deficiency, unspecified
0.099 0.901 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.099 0.901 0.000
E00-E07 Disorders of thyroid gland
0.088 0.903 0.009
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.904 0.096
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.096 0.904 0.000
E66.1 Drug-induced obesity
0.089 0.911 0.000
E66.0 Obesity due to excess calories
0.085 0.915 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.921 0.079
N42 Other disorders of prostate
0.077 0.923 0.000
N43 Hydrocele and spermatocele
0.070 0.928 0.002
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.064 0.930 0.006
E00 Congenital iodine-deficiency syndrome
0.064 0.930 0.006
E02 Subclinical iodine-deficiency hypothyroidism
0.064 0.930 0.006
E20-E35 Disorders of other endocrine glands
0.066 0.934 0.000
N35 Urethral stricture
0.065 0.934 0.000
E07 Other disorders of thyroid
0.059 0.935 0.005
N42.2 Atrophy of prostate
0.059 0.941 0.000
K50-K52 Noninfective enteritis and colitis
0.000 0.941 0.059
N48.8 Other specified disorders of penis
0.059 0.941 0.000
L58 Radiodermatitis
0.000 0.943 0.057
L55 Sunburn
0.000 0.943 0.057
E06 Thyroiditis
0.050 0.944 0.006
N42.3 Dysplasia of prostate
0.055 0.944 0.000
E25 Adrenogenital disorders
0.055 0.945 0.000
N42.1 Congestion and haemorrhage of prostate
0.054 0.946 0.000
N43.1 Infected hydrocele
0.052 0.946 0.002
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.947 0.053
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.948 0.052
N43.2 Other hydrocele
0.050 0.948 0.002
N43.0 Encysted hydrocele
0.050 0.948 0.002
E34 Other endocrine disorders
0.051 0.948 0.000
H54.7 Unspecified visual loss
0.050 0.950 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.046 0.950 0.005
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.046 0.950 0.005
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.046 0.950 0.005
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.046 0.950 0.005
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.046 0.950 0.005
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.046 0.950 0.005
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.046 0.950 0.005
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.046 0.950 0.005
H54 Blindness and low vision
0.050 0.950 0.000
N42.9 Disorder of prostate, unspecified
0.050 0.950 0.000
E07.9 Disorder of thyroid, unspecified
0.048 0.951 0.001
N35.8 Other urethral stricture
0.048 0.952 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.047 0.952 0.000
E32 Diseases of thymus
0.047 0.952 0.000
E31 Polyglandular dysfunction
0.047 0.952 0.000
E30 Disorders of puberty, not elsewhere classified
0.047 0.952 0.000
H54.4 Blindness, one eye
0.047 0.953 0.000
N35.1 Postinfective urethral stricture, not elsewhere classified
0.047 0.953 0.000
N35.0 Posttraumatic urethral stricture
0.047 0.953 0.000
E03 Other hypothyroidism
0.045 0.953 0.003
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.047 0.953 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.046 0.953 0.000
E07.1 Dyshormogenetic goitre
0.043 0.953 0.004
E07.0 Hypersecretion of calcitonin
0.043 0.953 0.004
E20 Hypoparathyroidism
0.046 0.954 0.000
E29 Testicular dysfunction
0.045 0.955 0.000
Z93.1 Gastrostomy status
0.001 0.955 0.044
E24 Cushing's syndrome
0.044 0.956 0.000
N43.4 Spermatocele
0.042 0.956 0.002
E26 Hyperaldosteronism
0.043 0.956 0.000
E06.1 Subacute thyroiditis
0.038 0.958 0.004
H54.0 Blindness, both eyes
0.042 0.958 0.000
H54.9 Unspecified visual impairment (binocular)
0.041 0.959 0.000
L55.9 Sunburn, unspecified
0.000 0.959 0.041
L55.8 Other sunburn
0.000 0.959 0.041
L55.2 Sunburn of third degree
0.000 0.959 0.041
L55.1 Sunburn of second degree
0.000 0.959 0.041
L55.0 Sunburn of first degree
0.000 0.959 0.041
L58.9 Radiodermatitis, unspecified
0.000 0.959 0.041
L58.1 Chronic radiodermatitis
0.000 0.959 0.041
L58.0 Acute radiodermatitis
0.000 0.959 0.041
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.959 0.041
N41 Inflammatory diseases of prostate
0.041 0.959 0.000
E34.0 Carcinoid syndrome
0.040 0.960 0.000
E06.5 Other chronic thyroiditis
0.036 0.960 0.005
E06.4 Drug-induced thyroiditis
0.036 0.960 0.005
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.036 0.960 0.005
E06.0 Acute thyroiditis
0.036 0.960 0.005
H54.5 Low vision, one eye
0.040 0.960 0.000
E06.9 Thyroiditis, unspecified
0.036 0.960 0.004
E05 Thyrotoxicosis [hyperthyroidism]
0.028 0.960 0.012
E25.9 Adrenogenital disorder, unspecified
0.039 0.960 0.000
E25.8 Other adrenogenital disorders
0.039 0.960 0.000
E34.8 Other specified endocrine disorders
0.039 0.961 0.000
E22 Hyperfunction of pituitary gland
0.039 0.961 0.000
H54.1 Blindness, one eye, low vision, other eye
0.038 0.962 0.000
L56.4 Polymorphous light eruption
0.000 0.962 0.038
L56.3 Solar urticaria
0.000 0.962 0.038
L56.2 Photocontact dermatitis [berloque dermatitis]
0.000 0.962 0.038
L56.1 Drug photoallergic response
0.000 0.962 0.038
L56.0 Drug phototoxic response
0.000 0.962 0.038
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation
0.000 0.962 0.037
L59.0 Erythema ab igne [dermatitis ab igne]
0.000 0.962 0.037
E34.5 Androgen resistance syndrome
0.037 0.963 0.000
E34.4 Constitutional tall stature
0.037 0.963 0.000
E34.3 Short stature, not elsewhere classified
0.037 0.963 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.037 0.963 0.000
E34.1 Other hypersecretion of intestinal hormones
0.037 0.963 0.000
H54.2 Low vision, both eyes
0.037 0.963 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.035 0.963 0.002
N42.8 Other specified disorders of prostate
0.037 0.963 0.000
N42.0 Calculus of prostate
0.036 0.964 0.000
H54.3 Unqualified visual loss, both eyes
0.036 0.964 0.000
E34.9 Endocrine disorder, unspecified
0.036 0.964 0.000
E03.1 Congenital hypothyroidism without goitre
0.034 0.964 0.002
E03.8 Other specified hypothyroidism
0.034 0.965 0.001
H54.6 Unqualified visual loss, one eye
0.035 0.965 0.000
E24.9 Cushing's syndrome, unspecified
0.034 0.965 0.000
E30.9 Disorder of puberty, unspecified
0.034 0.966 0.000
E30.8 Other disorders of puberty
0.034 0.966 0.000
E30.1 Precocious puberty
0.034 0.966 0.000
E30.0 Delayed puberty
0.034 0.966 0.000
E31.9 Polyglandular dysfunction, unspecified
0.034 0.966 0.000
E31.8 Other polyglandular dysfunction
0.034 0.966 0.000
E31.1 Polyglandular hyperfunction
0.034 0.966 0.000
E31.0 Autoimmune polyglandular failure
0.034 0.966 0.000
E32.9 Disease of thymus, unspecified
0.034 0.966 0.000
E32.8 Other diseases of thymus
0.034 0.966 0.000
E32.1 Abscess of thymus
0.034 0.966 0.000
E32.0 Persistent hyperplasia of thymus
0.034 0.966 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.034 0.966 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.034 0.966 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.034 0.966 0.000
E03.5 Myxoedema coma
0.032 0.966 0.002
E03.4 Atrophy of thyroid (acquired)
0.032 0.966 0.002
E03.3 Postinfectious hypothyroidism
0.032 0.966 0.002
Z93.3 Colostomy status
0.000 0.966 0.034
E28 Ovarian dysfunction
0.033 0.966 0.000
E20.8 Other hypoparathyroidism
0.033 0.967 0.000
E20.1 Pseudohypoparathyroidism
0.033 0.967 0.000
E20.0 Idiopathic hypoparathyroidism
0.033 0.967 0.000
E07.8 Other specified disorders of thyroid
0.029 0.967 0.005
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified
0.000 0.967 0.033
E29.9 Testicular dysfunction, unspecified
0.032 0.967 0.000
E29.8 Other testicular dysfunction
0.032 0.967 0.000
E29.0 Testicular hyperfunction
0.032 0.967 0.000
E20.9 Hypoparathyroidism, unspecified
0.032 0.968 0.000
E24.8 Other Cushing's syndrome
0.031 0.968 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.031 0.968 0.000
E24.3 Ectopic ACTH syndrome
0.031 0.968 0.000
E24.1 Nelson's syndrome
0.031 0.968 0.000
E26.9 Hyperaldosteronism, unspecified
0.031 0.969 0.000
E26.8 Other hyperaldosteronism
0.031 0.969 0.000
E26.1 Secondary hyperaldosteronism
0.031 0.969 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.029 0.969 0.002
E22.1 Hyperprolactinaemia
0.030 0.970 0.000
E29.1 Testicular hypofunction
0.030 0.970 0.000
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.970 0.029
N41.8 Other inflammatory diseases of prostate
0.029 0.970 0.000
N41.3 Prostatocystitis
0.029 0.970 0.000
N41.2 Abscess of prostate
0.029 0.970 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.025 0.971 0.004
E05.5 Thyroid crisis or storm
0.020 0.971 0.009
E05.4 Thyrotoxicosis factitia
0.020 0.971 0.009
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.020 0.971 0.009
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.020 0.971 0.009
H30-H36 Disorders of choroid and retina
0.029 0.971 0.000
J33.9 Nasal polyp, unspecified
0.028 0.972 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.028 0.972 0.000
E22.8 Other hyperfunction of pituitary gland
0.028 0.972 0.000
E24.2 Drug-induced Cushing's syndrome
0.028 0.972 0.000
E24.0 Pituitary-dependent Cushing's disease
0.028 0.972 0.000
E26.0 Primary hyperaldosteronism
0.027 0.973 0.000
E05.8 Other thyrotoxicosis
0.018 0.973 0.009
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.027 0.973 0.000
M06.9 Rheumatoid arthritis, unspecified
0.027 0.973 0.000
N41.0 Acute prostatitis
0.026 0.974 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.026 0.974 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.025 0.975 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.025 0.975 0.000
N88.2 Stricture and stenosis of cervix uteri
0.000 0.976 0.024
E28.9 Ovarian dysfunction, unspecified
0.024 0.976 0.000
E28.8 Other ovarian dysfunction
0.024 0.976 0.000
E28.1 Androgen excess
0.024 0.976 0.000
E28.0 Oestrogen excess
0.024 0.976 0.000
E28.3 Primary ovarian failure
0.024 0.976 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.024 0.976 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.024 0.976 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.000 0.976 0.024
N50 Other disorders of male genital organs
0.023 0.977 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.023 0.977 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.022 0.978 0.000
H31 Other disorders of choroid
0.022 0.978 0.000
E23 Hypofunction and other disorders of pituitary gland
0.021 0.979 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.021 0.979 0.000
E06.3 Autoimmune thyroiditis
0.015 0.980 0.005
E21.5 Disorder of parathyroid gland, unspecified
0.020 0.980 0.000
G63.2 Diabetic polyneuropathy
0.020 0.980 0.000
H30 Chorioretinal inflammation
0.019 0.981 0.000
E22.0 Acromegaly and pituitary gigantism
0.018 0.982 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.018 0.982 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.018 0.982 0.000
E21.4 Other specified disorders of parathyroid gland
0.017 0.982 0.000
E21.2 Other hyperparathyroidism
0.017 0.982 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.017 0.983 0.000
N50.9 Disorder of male genital organs, unspecified
0.017 0.983 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.017 0.983 0.000
H53-H54 Visual disturbances and blindness
0.017 0.983 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.016 0.983 0.000
H31.0 Chorioretinal scars
0.016 0.984 0.000
H31.1 Choroidal degeneration
0.016 0.984 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.016 0.984 0.000
M06 Other rheumatoid arthritis
0.016 0.984 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.002 0.984 0.014
H31.8 Other specified disorders of choroid
0.016 0.984 0.000
H31.9 Disorder of choroid, unspecified
0.016 0.984 0.000
H31.4 Choroidal detachment
0.016 0.984 0.000
H31.3 Choroidal haemorrhage and rupture
0.016 0.984 0.000
H31.2 Hereditary choroidal dystrophy
0.016 0.984 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.016 0.984 0.000
J45.9 Asthma, unspecified
0.015 0.985 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.015 0.985 0.000
E23.1 Drug-induced hypopituitarism
0.015 0.985 0.000
H32.8 Other chorioretinal disorders in diseases classified elsewhere
0.015 0.985 0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
0.015 0.985 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.000 0.985 0.015
L90.0 Lichen sclerosus et atrophicus
0.015 0.985 0.000
E04 Other non-toxic goitre
0.006 0.985 0.009
E23.7 Disorder of pituitary gland, unspecified
0.014 0.986 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.014 0.986 0.000
H30.8 Other chorioretinal inflammations
0.014 0.986 0.000
H30.2 Posterior cyclitis
0.014 0.986 0.000
H30.1 Disseminated chorioretinal inflammation
0.014 0.986 0.000
H30.0 Focal chorioretinal inflammation
0.014 0.986 0.000
E66.9 Obesity, unspecified
0.014 0.986 0.000
E23.6 Other disorders of pituitary gland
0.013 0.986 0.000
E27 Other disorders of adrenal gland
0.012 0.987 0.001
N30-N39 Other diseases of urinary system
0.013 0.987 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.013 0.987 0.000
M05 Seropositive rheumatoid arthritis
0.013 0.987 0.000
E05.9 Thyrotoxicosis, unspecified
0.001 0.987 0.012
N34 Urethritis and urethral syndrome
0.013 0.987 0.000
J33 Nasal polyp
0.013 0.987 0.000
N34.3 Urethral syndrome, unspecified
0.012 0.988 0.000
M06.3 Rheumatoid nodule
0.012 0.988 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.012 0.988 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.012 0.988 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.012 0.988 0.000
M06.8 Other specified rheumatoid arthritis
0.012 0.988 0.000
H34 Retinal vascular occlusions
0.012 0.988 0.000
N50.0 Atrophy of testis
0.012 0.988 0.000
H30.9 Chorioretinal inflammation, unspecified
0.012 0.988 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.012 0.988 0.000
N30.9 Cystitis, unspecified
0.012 0.988 0.000
M06.2 Rheumatoid bursitis
0.012 0.988 0.000
M06.1 Adult-onset Still's disease
0.012 0.988 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.012 0.988 0.000
M47.9 Spondylosis, unspecified
0.012 0.988 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.011 0.988 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.011 0.988 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.011 0.988 0.000
N30 Cystitis
0.012 0.988 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.011 0.989 0.000
M47 Spondylosis
0.011 0.989 0.000
M47.8 Other spondylosis
0.011 0.989 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.000 0.989 0.011
E04.8 Other specified non-toxic goitre
0.004 0.989 0.007
E66.8 Other obesity
0.011 0.989 0.000
M47.82 Other spondylosis (Cervical region)
0.011 0.989 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.011 0.989 0.000
E28.2 Polycystic ovarian syndrome
0.010 0.989 0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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