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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs5029394
log Bayes Factor = 57.4101
Chromosome 6   position 32,695,082  (GRCh37) Explore rs5029394 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
G35 Multiple sclerosis
1.000 0.000 0.000
E10.3 With ophthalmic complications
0.999 0.001 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.997 0.003 0.000
E10.1 With ketoacidosis
0.996 0.004 0.000
G37 Other demyelinating diseases of central nervous system
0.990 0.010 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.980 0.020 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.926 0.034 0.040
E10-E14 Diabetes mellitus
0.962 0.038 0.000
E10.5 With peripheral circulatory complications
0.954 0.046 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.939 0.061 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.934 0.065 0.001
Chapter IV Endocrine, nutritional and metabolic diseases
0.932 0.068 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.930 0.070 0.000
E10.4 With neurological complications
0.926 0.074 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.924 0.076 0.000
L60-L75 Disorders of skin appendages
0.920 0.078 0.002
L72.1 Trichilemmal cyst
0.922 0.078 0.000
E14 Unspecified diabetes mellitus
0.920 0.080 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.917 0.083 0.000
L20-L30 Dermatitis and eczema
0.903 0.096 0.001
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.903 0.097 0.000
# Top node
0.897 0.103 0.000
Chapter VII Diseases of the eye and adnexa
0.893 0.107 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.890 0.110 0.000
H00 Hordeolum and chalazion
0.887 0.113 0.000
Chapter VI Diseases of the nervous system
0.886 0.114 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.884 0.116 0.000
E16 Other disorders of pancreatic internal secretion
0.883 0.117 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.883 0.117 0.000
H00.1 Chalazion
0.882 0.118 0.000
E03 Other hypothyroidism
0.005 0.121 0.874
E16.2 Hypoglycaemia, unspecified
0.878 0.122 0.000
E50-E64 Other nutritional deficiencies
0.875 0.125 0.000
Chapter V Mental and behavioural disorders
0.873 0.127 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.866 0.134 0.000
E10.2 With renal complications
0.865 0.135 0.000
E14.9 Without complications
0.856 0.144 0.000
L27 Dermatitis due to substances taken internally
0.850 0.150 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.848 0.152 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.848 0.152 0.000
L04 Acute lymphadenitis
0.837 0.163 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.833 0.167 0.000
L40-L45 Papulosquamous disorders
0.037 0.168 0.795
H17 Corneal scars and opacities
0.832 0.168 0.000
H36.0 Diabetic retinopathy
0.829 0.171 0.000
H36 Retinal disorders in diseases classified elsewhere
0.825 0.175 0.000
H04 Disorders of lachrymal system
0.823 0.177 0.000
H30-H36 Disorders of choroid and retina
0.823 0.177 0.000
F20 Schizophrenia
0.822 0.178 0.000
L21 Seborrhoeic dermatitis
0.820 0.179 0.001
Q20-Q28 Congenital malformations of the circulatory system
0.820 0.180 0.000
F03 Unspecified dementia
0.820 0.180 0.000
Q66 Congenital deformities of feet
0.818 0.182 0.000
E55 Vitamin D deficiency
0.815 0.185 0.000
L40 Psoriasis
0.003 0.192 0.805
L71 Rosacea
0.804 0.195 0.001
L43 Lichen planus
0.011 0.197 0.791
L40.5 Arthropathic psoriasis
0.000 0.202 0.798
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.790 0.210 0.000
L43.9 Lichen planus, unspecified
0.000 0.213 0.787
H00.0 Hordeolum and other deep inflammation of eyelid
0.787 0.213 0.000
F20.9 Schizophrenia, unspecified
0.785 0.215 0.000
L30 Other dermatitis
0.785 0.215 0.000
L40.9 Psoriasis, unspecified
0.000 0.218 0.782
H17.9 Corneal scar and opacity, unspecified
0.780 0.220 0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.773 0.226 0.000
E55.9 Vitamin D deficiency, unspecified
0.772 0.228 0.000
E14.6 With other specified complications
0.771 0.229 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.771 0.229 0.000
L05 Pilonidal cyst
0.770 0.230 0.000
Q66.8 Other congenital deformities of feet
0.763 0.237 0.000
L70 Acne
0.760 0.239 0.001
L21.9 Seborrhoeic dermatitis, unspecified
0.761 0.239 0.000
E10.8 With unspecified complications
0.761 0.239 0.000
E14.3 With ophthalmic complications
0.757 0.243 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.755 0.245 0.000
F20.0 Paranoid schizophrenia
0.755 0.245 0.000
H01 Other inflammation of eyelid
0.754 0.246 0.000
G36 Other acute disseminated demyelination
0.745 0.254 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.003 0.255 0.742
F60-F69 Disorders of adult personality and behaviour
0.742 0.258 0.000
F23 Acute and transient psychotic disorders
0.737 0.263 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.736 0.264 0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.736 0.264 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.734 0.266 0.000
L27.1 Localised skin eruption due to drugs and medicaments
0.732 0.268 0.000
E03.8 Other specified hypothyroidism
0.002 0.269 0.729
E00-E07 Disorders of thyroid gland
0.032 0.272 0.696
H04.1 Other disorders of lachrymal gland
0.726 0.274 0.000
L65 Other nonscarring hair loss
0.723 0.275 0.001
E10.0 With coma
0.724 0.276 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.724 0.276 0.000
H20 Iridocyclitis
0.724 0.276 0.000
H16 Keratitis
0.721 0.279 0.000
H18 Other disorders of cornea
0.721 0.279 0.000
E10.7 With multiple complications
0.721 0.279 0.000
G63.2 Diabetic polyneuropathy
0.716 0.284 0.000
L23 Allergic contact dermatitis
0.714 0.285 0.001
F00 Dementia in Alzheimer's disease
0.715 0.285 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.713 0.287 0.000
E53 Deficiency of other B group vitamins
0.712 0.288 0.000
E10.6 With other specified complications
0.711 0.289 0.000
G37.5 Concentric sclerosis [Balo]
0.710 0.290 0.000
G37.4 Subacute necrotising myelitis
0.710 0.290 0.000
G37.2 Central pontine myelinolysis
0.710 0.290 0.000
G37.1 Central demyelination of corpus callosum
0.710 0.290 0.000
G37.0 Diffuse sclerosis
0.710 0.290 0.000
L01 Impetigo
0.706 0.294 0.000
H04.2 Epiphora
0.706 0.294 0.000
Q74 Other congenital malformations of limb(s)
0.704 0.296 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.702 0.298 0.000
F01 Vascular dementia
0.702 0.298 0.000
L30.8 Other specified dermatitis
0.698 0.302 0.000
L04.2 Acute lymphadenitis of upper limb
0.696 0.304 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.694 0.306 0.000
L63 Alopecia areata
0.691 0.307 0.001
E12 Malnutrition-related diabetes mellitus
0.690 0.310 0.000
H04.8 Other disorders of lachrymal system
0.689 0.311 0.000
E63 Other nutritional deficiencies
0.687 0.313 0.000
Q35-Q37 Cleft lip and cleft palate
0.687 0.313 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.684 0.316 0.000
H01.0 Blepharitis
0.684 0.316 0.000
L04.8 Acute lymphadenitis of other sites
0.674 0.326 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.673 0.327 0.000
G30-G32 Other degenerative diseases of the nervous system
0.671 0.329 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.671 0.329 0.000
E14.2 Withrenal complications
0.671 0.329 0.000
L00 Staphylococcal scalded skin syndrome
0.670 0.330 0.001
E14.5 With peripheral circulatory complications
0.669 0.331 0.000
F60 Specific personality disorders
0.669 0.331 0.000
H17.8 Other corneal scars and opacities
0.668 0.332 0.000
H55-H59 Other disorders of eye and adnexa
0.668 0.332 0.000
H15 Disorders of sclera
0.666 0.334 0.000
L71.1 Rhinophyma
0.664 0.335 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.663 0.337 0.000
L20 Atopic dermatitis
0.661 0.338 0.001
Q23 Congenital malformations of aortic and mitral valves
0.662 0.338 0.000
Q78 Other osteochondrodysplasias
0.661 0.339 0.000
L75 Apocrine sweat disorders
0.660 0.339 0.002
L74 Eccrine sweat disorders
0.660 0.339 0.002
L67 Hair colour and hair shaft abnormalities
0.660 0.339 0.002
L64 Androgenic alopecia
0.660 0.339 0.002
L62 Nail disorders in diseases classified elsewhere
0.660 0.339 0.002
E06 Thyroiditis
0.015 0.339 0.646
E14.7 With multiple complications
0.660 0.340 0.000
E14.1 With ketoacidosis
0.660 0.340 0.000
E14.0 With coma
0.660 0.340 0.000
Q25 Congenital malformations of great arteries
0.659 0.341 0.000
H18.6 Keratoconus
0.659 0.341 0.000
L72.2 Steatocystoma multiplex
0.657 0.342 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.656 0.344 0.000
L25 Unspecified contact dermatitis
0.654 0.345 0.001
E14.8 With unspecified complications
0.655 0.345 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.654 0.346 0.000
L43.8 Other lichen planus
0.006 0.350 0.644
L04.1 Acute lymphadenitis of trunk
0.649 0.351 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.649 0.351 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.649 0.351 0.000
L24 Irritant contact dermatitis
0.647 0.352 0.001
L26 Exfoliative dermatitis
0.647 0.352 0.001
L22 Diaper [napkin] dermatitis
0.647 0.352 0.001
L05.0 Pilonidal cyst with abscess
0.648 0.352 0.000
E15 Nondiabetic hypoglycaemic coma
0.648 0.352 0.000
Q65 Congenital deformities of hip
0.646 0.354 0.000
H16.0 Corneal ulcer
0.646 0.354 0.000
Q24 Other congenital malformations of heart
0.646 0.354 0.000
Q21 Congenital malformations of cardiac septa
0.645 0.355 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.644 0.356 0.000
L71.9 Rosacea, unspecified
0.644 0.356 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.643 0.357 0.000
Q66.0 Talipes equinovarus
0.642 0.358 0.000
Q66.3 Other congenital varus deformities of feet
0.642 0.358 0.000
E83.1 Disorders of iron metabolism
0.641 0.359 0.000
L04.0 Acute lymphadenitis of face, head and neck
0.639 0.360 0.000
F20.8 Other schizophrenia
0.640 0.360 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.637 0.361 0.002
E05 Thyrotoxicosis [hyperthyroidism]
0.007 0.361 0.631
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.638 0.362 0.000
E40-E46 Malnutrition
0.636 0.364 0.000
L42 Pityriasis rosea
0.022 0.365 0.613
L40.1 Generalised pustular psoriasis
0.002 0.366 0.633
Q28 Other congenital malformations of circulatory system
0.634 0.366 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.633 0.367 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.633 0.367 0.000
E16.4 Abnormal secretion of gastrin
0.633 0.367 0.000
E16.3 Increased secretion of glucagon
0.633 0.367 0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis
0.631 0.369 0.000
F23.9 Acute and transient psychotic disorder, unspecified
0.630 0.370 0.000
E03.5 Myxoedema coma
0.004 0.370 0.627
E03.4 Atrophy of thyroid (acquired)
0.004 0.370 0.627
E03.3 Postinfectious hypothyroidism
0.004 0.370 0.627
L30.1 Dyshidrosis [pompholyx]
0.628 0.372 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.627 0.372 0.000
E56 Other vitamin deficiencies
0.627 0.372 0.000
E51 Thiamine deficiency
0.627 0.372 0.000
E50 Vitamin A deficiency
0.627 0.372 0.000
E60 Dietary zinc deficiency
0.627 0.372 0.000
E59 Dietary selenium deficiency
0.627 0.372 0.000
E54 Ascorbic acid deficiency
0.627 0.372 0.000
E52 Niacin deficiency [pellagra]
0.627 0.372 0.000
Q66.2 Metatarsus varus
0.627 0.373 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.626 0.374 0.000
E06.3 Autoimmune thyroiditis
0.002 0.374 0.623
F70-F79 Mental retardation
0.623 0.377 0.000
F80-F89 Disorders of psychological development
0.617 0.383 0.000
L27.2 Dermatitis due to ingested food
0.616 0.384 0.000
H21 Other disorders of iris and ciliary body
0.615 0.385 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.615 0.385 0.000
Q66.6 Other congenital valgus deformities of feet
0.614 0.386 0.000
H31 Other disorders of choroid
0.614 0.386 0.000
L71.8 Other rosacea
0.613 0.386 0.000
L68 Hypertrichosis
0.610 0.388 0.002
L27.9 Dermatitis due to unspecified substance taken internally
0.609 0.390 0.000
L27.8 Dermatitis due to other substances taken internally
0.609 0.390 0.000
H20.9 Iridocyclitis, unspecified
0.610 0.390 0.000
L70.9 Acne, unspecified
0.608 0.391 0.001
G80-G83 Cerebral palsy and other paralytic syndromes
0.609 0.391 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.608 0.392 0.000
Q75 Other congenital malformations of skull and face bones
0.608 0.392 0.000
Q73 Reduction defects of unspecified limb
0.608 0.392 0.000
Q72 Reduction defects of lower limb
0.608 0.392 0.000
Q71 Reduction defects of upper limb
0.608 0.392 0.000
Q70 Syndactyly
0.608 0.392 0.000
Q69 Polydactyly
0.608 0.392 0.000
Q68 Other congenital musculoskeletal deformities
0.608 0.392 0.000
F09 Unspecified organic or symptomatic mental disorder
0.608 0.392 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.608 0.392 0.000
Q27 Other congenital malformations of peripheral vascular system
0.608 0.392 0.000
E53.9 Vitamin B deficiency, unspecified
0.606 0.394 0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia
0.603 0.397 0.000
L57.0 Actinic keratosis
0.000 0.397 0.603
E58 Dietary calcium deficiency
0.601 0.398 0.000
L04.3 Acute lymphadenitis of lower limb
0.600 0.399 0.000
L40.0 Psoriasis vulgaris
0.001 0.400 0.599
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle
0.599 0.401 0.000
L70.0 Acne vulgaris
0.598 0.401 0.001
F28 Other nonorganic psychotic disorders
0.597 0.403 0.000
F24 Induced delusional disorder
0.597 0.403 0.000
F21 Schizotypal disorder
0.597 0.403 0.000
F01.9 Vascular dementia, unspecified
0.597 0.403 0.000
L44 Other papulosquamous disorders
0.027 0.403 0.570
L41 Parapsoriasis
0.027 0.403 0.570
L45 Papulosquamous disorders in diseases classified elsewhere
0.027 0.403 0.570
H17.1 Other central corneal opacity
0.597 0.403 0.000
H17.0 Adherent leukoma
0.597 0.403 0.000
Chapter XXII Codes for special purposes
0.594 0.406 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.001 0.406 0.593
Q66.7 Pes cavus
0.593 0.407 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.591 0.409 0.000
H04.0 Dacryoadenitis
0.590 0.410 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.590 0.410 0.000
F20.6 Simple schizophrenia
0.589 0.411 0.000
F20.4 Postschizophrenic depression
0.589 0.411 0.000
F20.3 Undifferentiated schizophrenia
0.589 0.411 0.000
F20.2 Catatonic schizophrenia
0.589 0.411 0.000
F20.1 Hebephrenic schizophrenia
0.589 0.411 0.000
F50 Eating disorders
0.589 0.411 0.000
L21.8 Other seborrhoeic dermatitis
0.588 0.412 0.001
L21.1 Seborrhoeic infantile dermatitis
0.588 0.412 0.001
L21.0 Seborrhoea capitis
0.588 0.412 0.001
Q26 Congenital malformations of great veins
0.588 0.412 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.588 0.412 0.000
F60.3 Emotionally unstable personality disorder
0.587 0.413 0.000
Q66.9 Congenital deformity of feet, unspecified
0.586 0.414 0.000
Q66.5 Congenital pes planus
0.586 0.414 0.000
Q66.4 Talipes calcaneovalgus
0.586 0.414 0.000
Q66.1 Talipes calcaneovarus
0.586 0.414 0.000
F07.0 Organic personality disorder
0.586 0.414 0.000
E55.0 Rickets, active
0.584 0.415 0.000
F20.5 Residual schizophrenia
0.584 0.415 0.000
L65.9 Nonscarring hair loss, unspecified
0.582 0.417 0.001
L04.9 Acute lymphadenitis, unspecified
0.582 0.417 0.000
L40.4 Guttate psoriasis
0.002 0.421 0.577
L40.3 Pustulosis palmaris et plantaris
0.002 0.421 0.577
L40.2 Acrodermatitis continua
0.002 0.421 0.577
L71.0 Perioral dermatitis
0.577 0.423 0.001
Q79.6 Ehlers-Danlos syndrome
0.576 0.424 0.000
L43.3 Subacute (active) lichen planus
0.008 0.424 0.567
L43.2 Lichenoid drug reaction
0.008 0.424 0.567
L43.1 Bullous lichen planus
0.008 0.424 0.567
L43.0 Hypertrophic lichen planus
0.008 0.424 0.567
L08 Other local infections of skin and subcutaneous tissue
0.575 0.424 0.000
L23.1 Allergic contact dermatitis due to adhesives
0.574 0.425 0.000
E61 Deficiency of other nutrient elements
0.572 0.428 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.570 0.430 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.353 0.433 0.213
G36.0 Neuromyelitis optica [Devic]
0.565 0.434 0.000
H18.9 Disorder of cornea, unspecified
0.565 0.435 0.000
Q17 Other congenital malformations of ear
0.563 0.437 0.000
L30.5 Pityriasis alba
0.563 0.437 0.000
L30.3 Infective dermatitis
0.563 0.437 0.000
L30.2 Cutaneous autosensitisation
0.563 0.437 0.000
L30.0 Nummular dermatitis
0.563 0.437 0.000
E14.4 With neurological complications
0.562 0.438 0.000
H01.1 Non-infectious dermatoses of eyelid
0.561 0.439 0.000
L05.9 Pilonidal cyst without abscess
0.560 0.440 0.000
H20.8 Other iridocyclitis
0.560 0.440 0.000
F07.2 Postconcussional syndrome
0.559 0.441 0.000
Q35 Cleft palate
0.558 0.442 0.000
Q96 Turner's syndrome
0.558 0.442 0.000
L23.9 Allergic contact dermatitis, unspecified cause
0.558 0.442 0.001
E03.0 Congenital hypothyroidism with diffuse goitre
0.004 0.443 0.552
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.555 0.445 0.000
E03.1 Congenital hypothyroidism without goitre
0.004 0.447 0.549
L10-L14 Bullous disorders
0.521 0.447 0.031
E63.9 Nutritional deficiency, unspecified
0.552 0.448 0.000
Q23.1 Congenital insufficiency of aortic valve
0.550 0.450 0.000
H57 Other disorders of eye and adnexa
0.547 0.453 0.000
L70.8 Other acne
0.545 0.454 0.001
L70.5 Acne excoriee des jeunes filles
0.545 0.454 0.001
L70.4 Infantile acne
0.545 0.454 0.001
L70.3 Acne tropica
0.545 0.454 0.001
L70.2 Acne varioliformis
0.545 0.454 0.001
L70.1 Acne conglobata
0.545 0.454 0.001
F60.7 Dependent personality disorder
0.544 0.456 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.543 0.456 0.000
Q21.0 Ventricular septal defect
0.543 0.457 0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos
0.543 0.457 0.000
L01.0 Impetigo [any organism] [any site]
0.542 0.458 0.000
H30 Chorioretinal inflammation
0.542 0.458 0.000
Q25.1 Coarctation of aorta
0.541 0.459 0.000
Q22.5 Ebstein's anomaly
0.540 0.460 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.539 0.461 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.539 0.461 0.000
H04.6 Other changes in lachrymal passages
0.539 0.461 0.000
F99-F99 Unspecified mental disorder
0.535 0.464 0.000
H16.8 Other keratitis
0.535 0.465 0.000
Q25.0 Patent ductus arteriosus
0.535 0.465 0.000
G36.9 Acute disseminated demyelination, unspecified
0.534 0.465 0.000
G36.8 Other specified acute disseminated demyelination
0.534 0.465 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.534 0.465 0.000
Q31 Congenital malformations of larynx
0.534 0.466 0.000
H18.2 Other corneal oedema
0.534 0.466 0.000
H53-H54 Visual disturbances and blindness
0.533 0.467 0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere
0.533 0.467 0.000
F51 Nonorganic sleep disorders
0.533 0.467 0.000
F68 Other disorders of adult personality and behaviour
0.532 0.468 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.532 0.468 0.000
F65 Disorders of sexual preference
0.532 0.468 0.000
F63 Habit and impulse disorders
0.532 0.468 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.532 0.468 0.000
F61 Mixed and other personality disorders
0.532 0.468 0.000
G30 Alzheimer's disease
0.531 0.469 0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle
0.531 0.469 0.000
G70-G73 Diseases of myoneural junction and muscle
0.530 0.470 0.000
H15.0 Scleritis
0.529 0.470 0.000
H01.8 Other specified inflammation of eyelid
0.529 0.471 0.000
F23.8 Other acute and transient psychotic disorders
0.529 0.471 0.000
F23.3 Other acute predominantly delusional psychotic disorders
0.529 0.471 0.000
F23.2 Acute schizophrenia-like psychotic disorder
0.529 0.471 0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia
0.529 0.471 0.000
L63.9 Alopecia areata, unspecified
0.527 0.472 0.001
G64 Other disorders of peripheral nervous system
0.528 0.472 0.000
H18.4 Corneal degeneration
0.528 0.472 0.000
Q78.0 Osteogenesis imperfecta
0.527 0.473 0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere
0.526 0.473 0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere
0.526 0.473 0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere
0.526 0.473 0.000
L30.4 Erythema intertrigo
0.526 0.474 0.000
F55 Abuse of non-dependence-producing substances
0.526 0.474 0.000
Q21.8 Other congenital malformations of cardiac septa
0.526 0.474 0.000
H18.1 Bullous keratopathy
0.525 0.475 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.475 0.524
H04.9 Disorder of lachrymal system, unspecified
0.524 0.476 0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit
0.523 0.477 0.000
L30.9 Dermatitis, unspecified
0.523 0.477 0.000
Q24.9 Congenital malformation of the heart, unspecified
0.523 0.477 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.023 0.478 0.499
E00 Congenital iodine-deficiency syndrome
0.023 0.478 0.499
Q67.6 Pectus excavatum
0.522 0.478 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.521 0.479 0.000
H21.1 Other vascular disorders of iris and ciliary body
0.521 0.479 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.520 0.479 0.000
L65.8 Other specified nonscarring hair loss
0.519 0.480 0.001
L65.2 Alopecia mucinosa
0.519 0.480 0.001
L65.1 Anagen effluvium
0.519 0.480 0.001
L65.0 Telogen effluvium
0.519 0.480 0.001
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere
0.519 0.481 0.000
G63.8 Polyneuropathy in other diseases classified elsewhere
0.519 0.481 0.000
G63.6 Polyneuropathy in other musculoskeletal disorders
0.519 0.481 0.000
G63.5 Polyneuropathy in systemic connective tissue disorders
0.519 0.481 0.000
G63.4 Polyneuropathy in nutritional deficiency
0.519 0.481 0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.519 0.481 0.000
G63.1 Polyneuropathy in neoplastic disease
0.519 0.481 0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.519 0.481 0.000
H20.2 Lens-induced iridocyclitis
0.519 0.481 0.000
H16.4 Corneal neovascularisation
0.519 0.481 0.000
H16.3 Interstitial and deep keratitis
0.517 0.483 0.000
H18.7 Other corneal deformities
0.517 0.483 0.000
H18.3 Changes in corneal membranes
0.517 0.483 0.000
H18.0 Corneal pigmentations and deposits
0.517 0.483 0.000
H20.1 Chronic iridocyclitis
0.516 0.484 0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified
0.515 0.485 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.515 0.485 0.000
Q60-Q64 Congenital malformations of the urinary system
0.514 0.486 0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.513 0.487 0.000
L23.8 Allergic contact dermatitis due to other agents
0.512 0.487 0.001
L23.7 Allergic contact dermatitis due to plants, except food
0.512 0.487 0.001
L23.6 Allergic contact dermatitis due to food in contact with the skin
0.512 0.487 0.001
L23.4 Allergic contact dermatitis due to dyes
0.512 0.487 0.001
L23.3 Allergic contact dermatitis due to drugs in contact with the skin
0.512 0.487 0.001
L23.2 Allergic contact dermatitis due to cosmetics
0.512 0.487 0.001
L23.0 Allergic contact dermatitis due to metals
0.512 0.487 0.001
F00.1 Dementia in Alzheimer's disease with late onset
0.512 0.488 0.000
F60.5 Anankastic personality disorder
0.512 0.488 0.000
Q28.2 Arteriovenous malformation of cerebral vessels
0.511 0.489 0.000
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction
0.511 0.489 0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction
0.511 0.489 0.000
F07.1 Postencephalitic syndrome
0.511 0.489 0.000
E53.1 Pyridoxine deficiency
0.510 0.490 0.000
E53.0 Riboflavin deficiency
0.510 0.490 0.000
F64 Gender identity disorders
0.510 0.490 0.000
Q24.5 Malformation of coronary vessels
0.509 0.491 0.000
L01.1 Impetiginisation of other dermatoses
0.506 0.494 0.000
Q74.9 Unspecified congenital malformation of limb(s)
0.505 0.495 0.000
Q74.8 Other specified congenital malformations of limb(s)
0.505 0.495 0.000
Q74.3 Arthrogryposis multiplex congenita
0.505 0.495 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.503 0.497 0.000
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors
0.503 0.497 0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere
0.503 0.497 0.000
F01.8 Other vascular dementia
0.503 0.497 0.000
F01.3 Mixed cortical and subcortical vascular dementia
0.503 0.497 0.000
F01.2 Subcortical vascular dementia
0.503 0.497 0.000
F01.1 Multi-infarct dementia
0.503 0.497 0.000
F01.0 Vascular dementia of acute onset
0.503 0.497 0.000
H16.1 Other superficial keratitis without conjunctivitis
0.502 0.498 0.000
Q65.8 Other congenital deformities of hip
0.501 0.499 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.023 0.501 0.477
E13 Other specified diabetes mellitus
0.498 0.501 0.000
F69 Unspecified disorder of adult personality and behaviour
0.498 0.501 0.000
Q99 Other chromosome abnormalities, not elsewhere classified
0.498 0.502 0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified
0.498 0.502 0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified
0.498 0.502 0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified
0.498 0.502 0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified
0.498 0.502 0.000
Q91 Edwards' syndrome and Patau's syndrome
0.498 0.502 0.000
Q90 Down's syndrome
0.498 0.502 0.000
Q67.4 Other congenital deformities of skull, face and jaw
0.497 0.503 0.000
L63.8 Other alopecia areata
0.496 0.503 0.001
L63.2 Ophiasis
0.496 0.503 0.001
L63.1 Alopecia universalis
0.496 0.503 0.001
L63.0 Alopecia (capitis) totalis
0.496 0.503 0.001
L08.8 Other specified local infections of skin and subcutaneous tissue
0.496 0.503 0.000
L40.8 Other psoriasis
0.002 0.504 0.493
L50-L54 Urticaria and erythema
0.477 0.505 0.018
L20.8 Other atopic dermatitis
0.495 0.505 0.001
E12.9 Without complications
0.495 0.505 0.000
E12.8 With unspecified complications
0.495 0.505 0.000
E12.7 With multiple complications
0.495 0.505 0.000
E12.6 With other specified complications
0.495 0.505 0.000
E12.5 With peripheral circulatory complications
0.495 0.505 0.000
E12.4 With neurological complications
0.495 0.505 0.000
E12.3 With ophthalmic complications
0.495 0.505 0.000
E12.2 With renal complications
0.495 0.505 0.000
E12.1 With ketoacidosis
0.495 0.505 0.000
E12.0 With coma
0.495 0.505 0.000
H10-H13 Disorders of conjunctiva
0.494 0.506 0.000
G83 Other paralytic syndromes
0.494 0.506 0.000
F60.9 Personality disorder, unspecified
0.493 0.507 0.000
E63.8 Other specified nutritional deficiencies
0.493 0.507 0.000
E63.1 Imbalance of constituents of food intake
0.493 0.507 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.493 0.507 0.000
Q37 Cleft palate with cleft lip
0.492 0.507 0.000
Q36 Cleft lip
0.492 0.507 0.000
Q16 Congenital malformations of ear causing impairment of hearing
0.490 0.510 0.000
Q15 Other congenital malformations of eye
0.490 0.510 0.000
Q13 Congenital malformations of anterior segment of eye
0.490 0.510 0.000
E53.8 Deficiency of other specified B group vitamins
0.489 0.510 0.000
H31.8 Other specified disorders of choroid
0.489 0.511 0.000
H05 Disorders of orbit
0.487 0.513 0.000
Q21.9 Congenital malformation of cardiac septum, unspecified
0.487 0.513 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.487 0.513 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.484 0.516 0.000
F50.2 Bulimia nervosa
0.483 0.517 0.000
L72.0 Epidermal cyst
0.483 0.517 0.000
H21.2 Degeneration of iris and ciliary body
0.483 0.517 0.000
H16.9 Keratitis, unspecified
0.483 0.517 0.000
Q34 Other congenital malformations of respiratory system
0.482 0.517 0.000
Q33 Congenital malformations of lung
0.482 0.517 0.000
Q32 Congenital malformations of trachea and bronchus
0.482 0.517 0.000
Q30 Congenital malformations of nose
0.482 0.517 0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified
0.481 0.519 0.000
Q79.5 Other congenital malformations of abdominal wall
0.481 0.519 0.000
Q79.4 Prune belly syndrome
0.481 0.519 0.000
Q79.3 Gastroschisis
0.481 0.519 0.000
Q79.2 Exomphalos
0.481 0.519 0.000
Q79.1 Other congenital malformations of diaphragm
0.481 0.519 0.000
Q79.0 Congenital diaphragmatic hernia
0.481 0.519 0.000
Q74.1 Congenital malformation of knee
0.481 0.519 0.000
F02 Dementia in other diseases classified elsewhere
0.480 0.519 0.000
F60.0 Paranoid personality disorder
0.480 0.520 0.000
H22.1 Iridocyclitis in other diseases classified elsewhere
0.480 0.520 0.000
Q21.3 Tetralogy of Fallot
0.480 0.520 0.000
F60.8 Other specific personality disorders
0.479 0.521 0.000
F60.4 Histrionic personality disorder
0.479 0.521 0.000
F60.2 Dissocial personality disorder
0.479 0.521 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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