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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs503279
log Bayes Factor = 19.8281
Chromosome 19   position 49,209,010  (GRCh37) Explore rs503279 on Ensembl!
Variant rs503279 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K80.1 Calculus of gallbladder with other cholecystitis
0.000 0.000 1.000
K80 Cholelithiasis
0.000 0.000 1.000
K80.2 Calculus of gallbladder without cholecystitis
0.000 0.000 1.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.000 0.000 1.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.000 1.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.000 1.000
K29 Gastritis and duodenitis
0.000 0.000 1.000
K26 Duodenal ulcer
0.000 0.000 1.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.000 0.001 0.999
I10 Essential (primary) hypertension
0.000 0.001 0.999
K29.8 Duodenitis
0.000 0.001 0.999
K82 Other diseases of gallbladder
0.000 0.004 0.996
Chapter XI Diseases of the digestive system
0.000 0.005 0.995
K82.4 Cholesterolosis of gallbladder
0.000 0.015 0.985
E78.0 Pure hypercholesterolaemia
0.000 0.019 0.981
K65-K67 Diseases of peritoneum
0.000 0.021 0.979
K29.0 Acute haemorrhagic gastritis
0.000 0.023 0.977
K66 Other disorders of peritoneum
0.000 0.052 0.948
K83 Other diseases of biliary tract
0.000 0.058 0.942
K82.8 Other specified diseases of gallbladder
0.000 0.058 0.942
K83.1 Obstruction of bile duct
0.000 0.078 0.922
K29.5 Chronic gastritis, unspecified
0.000 0.083 0.917
K66.0 Peritoneal adhesions
0.000 0.084 0.916
K31 Other diseases of stomach and duodenum
0.000 0.085 0.915
K29.4 Chronic atrophic gastritis
0.000 0.088 0.912
K82.9 Disease of gallbladder, unspecified
0.000 0.103 0.897
K65 Peritonitis
0.000 0.122 0.878
K31.8 Other specified diseases of stomach and duodenum
0.000 0.123 0.877
K83.0 Cholangitis
0.000 0.128 0.872
K66.8 Other specified disorders of peritoneum
0.000 0.129 0.871
K26.4 Chronic or unspecified with haemorrhage
0.000 0.152 0.848
K26.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.186 0.814
K31.9 Disease of stomach and duodenum, unspecified
0.000 0.191 0.809
K26.7 Chronic without haemorrhage or perforation
0.000 0.193 0.807
K65.8 Other peritonitis
0.000 0.199 0.801
K26.1 Acute with perforation
0.000 0.201 0.799
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.000 0.213 0.787
K29.3 Chronic superficial gastritis
0.000 0.220 0.780
K27 Peptic ulcer, site unspecified
0.000 0.223 0.777
K29.2 Alcoholic gastritis
0.000 0.232 0.768
K26.2 Acute with both haemorrhage and perforation
0.000 0.239 0.761
K23 Disorders of oesophagus in diseases classified elsewhere
0.000 0.245 0.755
K31.4 Gastric diverticulum
0.000 0.270 0.730
K70-K77 Diseases of liver
0.000 0.280 0.720
K80.3 Calculus of bile duct with cholangitis
0.000 0.283 0.717
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.283 0.717
K29.9 Gastroduodenitis, unspecified
0.000 0.283 0.717
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.284 0.716
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.285 0.715
K80.8 Other cholelithiasis
0.000 0.287 0.713
I83 Varicose veins of lower extremities
0.000 0.294 0.706
I80 Phlebitis and thrombophlebitis
0.000 0.296 0.704
K66.9 Disorder of peritoneum, unspecified
0.000 0.298 0.702
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.000 0.298 0.702
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.304 0.696
K31.2 Hourglass stricture and stenosis of stomach
0.000 0.304 0.696
K83.5 Biliary cyst
0.000 0.324 0.676
K82.3 Fistula of gallbladder
0.000 0.324 0.676
K83.9 Disease of biliary tract, unspecified
0.000 0.329 0.671
K27.7 Chronic without haemorrhage or perforation
0.000 0.332 0.668
K65.0 Acute peritonitis
0.000 0.335 0.665
K31.3 Pylorospasm, not elsewhere classified
0.000 0.335 0.665
K31.1 Adult hypertrophic pyloric stenosis
0.000 0.338 0.662
K31.0 Acute dilatation of stomach
0.000 0.342 0.658
I10-I15 Hypertensive diseases
0.000 0.342 0.658
K28 Gastrojejunal ulcer
0.000 0.345 0.655
K70 Alcoholic liver disease
0.000 0.345 0.655
K26.0 Acute with haemorrhage
0.000 0.350 0.650
K82.2 Perforation of gallbladder
0.000 0.352 0.648
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.360 0.640
K70.3 Alcoholic cirrhosis of liver
0.000 0.361 0.639
K65.9 Peritonitis, unspecified
0.000 0.392 0.608
K73 Chronic hepatitis, not elsewhere classified
0.000 0.392 0.608
I85 Oesophageal varices
0.000 0.396 0.604
K25 Gastric ulcer
0.000 0.402 0.598
K83.2 Perforation of bile duct
0.000 0.408 0.591
K82.0 Obstruction of gallbladder
0.000 0.410 0.589
K31.6 Fistula of stomach and duodenum
0.000 0.415 0.585
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.416 0.584
K23.8 Disorders of oesophagus in other diseases classified elsewhere
0.000 0.421 0.579
I88 Nonspecific lymphadenitis
0.000 0.429 0.571
K74 Fibrosis and cirrhosis of liver
0.000 0.436 0.564
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.442 0.558
K27.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.443 0.557
K27.5 Chronic or unspecified with perforation
0.000 0.443 0.557
K27.4 Chronic or unspecified with haemorrhage
0.000 0.443 0.557
K27.2 Acute with both haemorrhage and perforation
0.000 0.443 0.557
K27.1 Acute with perforation
0.000 0.443 0.557
K27.0 Acute with haemorrhage
0.000 0.443 0.557
Chapter IX Diseases of the circulatory system
0.000 0.443 0.557
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.443 0.557
K26.3 Acute without haemorrhage or perforation
0.000 0.452 0.547
K25.3 Acute without haemorrhage or perforation
0.000 0.453 0.547
K83.4 Spasm of sphincter of Oddi
0.000 0.454 0.546
K83.3 Fistula of bile duct
0.000 0.456 0.544
K23.1 Megaoesophagus in Chagas' disease
0.000 0.459 0.541
K23.0 Tuberculous oesophagitis
0.000 0.459 0.541
I85.9 Oesophageal varices without bleeding
0.000 0.462 0.538
K26.5 Chronic or unspecified with perforation
0.000 0.465 0.535
K77 Liver disorders in diseases classified elsewhere
0.000 0.483 0.517
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.484 0.516
K27.3 Acute without haemorrhage or perforation
0.000 0.484 0.516
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction
0.000 0.486 0.514
K87.1 Disorders of pancreas in diseases classified elsewhere
0.000 0.486 0.514
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere
0.000 0.486 0.514
I15 Secondary hypertension
0.000 0.490 0.510
K82.1 Hydrops of gallbladder
0.000 0.491 0.509
K31.5 Obstruction of duodenum
0.000 0.491 0.509
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.493 0.507
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere
0.000 0.497 0.503
K67.3 Tuberculous peritonitis
0.000 0.497 0.503
K67.2 Syphilitic peritonitis
0.000 0.497 0.503
K67.1 Gonococcal peritonitis
0.000 0.497 0.503
K67.0 Chlamydial peritonitis
0.000 0.497 0.503
K73.9 Chronic hepatitis, unspecified
0.000 0.500 0.500
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.502 0.498
K74.0 Hepatic fibrosis
0.000 0.511 0.489
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.511 0.489
I82 Other venous embolism and thrombosis
0.000 0.514 0.486
K90-K93 Other diseases of the digestive system
0.000 0.514 0.486
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.526 0.474
I13 Hypertensive heart and renal disease
0.000 0.528 0.471
K28.7 Chronic without haemorrhage or perforation
0.000 0.530 0.470
K28.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.530 0.470
K28.5 Chronic or unspecified with perforation
0.000 0.530 0.470
K28.4 Chronic or unspecified with haemorrhage
0.000 0.530 0.470
K28.3 Acute without haemorrhage or perforation
0.000 0.530 0.470
K28.2 Acute with both haemorrhage and perforation
0.000 0.530 0.470
K28.1 Acute with perforation
0.000 0.530 0.470
K28.0 Acute with haemorrhage
0.000 0.530 0.470
K25.5 Chronic or unspecified with perforation
0.000 0.536 0.464
K76 Other diseases of liver
0.000 0.538 0.462
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.540 0.460
K50-K52 Noninfective enteritis and colitis
0.000 0.541 0.459
K29.1 Other acute gastritis
0.000 0.547 0.453
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.556 0.444
K70.9 Alcoholic liver disease, unspecified
0.000 0.557 0.443
K85 Acute pancreatitis
0.000 0.560 0.440
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.562 0.438
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.564 0.436
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.564 0.436
K74.5 Biliary cirrhosis, unspecified
0.000 0.565 0.435
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.568 0.432
I85.0 Oesophageal varices with bleeding
0.000 0.570 0.430
I87 Other disorders of veins
0.000 0.571 0.429
K25.2 Acute with both haemorrhage and perforation
0.000 0.571 0.429
K25.1 Acute with perforation
0.000 0.571 0.429
K71 Toxic liver disease
0.000 0.575 0.425
I15.9 Seconday hypertension, unspecified
0.000 0.577 0.423
K72 Hepatic failure, not elsewhere classified
0.000 0.582 0.418
K25.7 Chronic without haemorrhage or perforation
0.000 0.583 0.417
I88.8 Other nonspecific lymphadenitis
0.000 0.583 0.417
K50 Crohn's disease [regional enteritis]
0.000 0.584 0.416
K74.6 Other and unspecified cirrhosis of liver
0.000 0.585 0.415
K76.8 Other specified diseases of liver
0.000 0.589 0.411
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.590 0.410
K25.4 Chronic or unspecified with haemorrhage
0.000 0.592 0.408
K28.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.592 0.408
K50.1 Crohn's disease of large intestine
0.000 0.595 0.405
K74.4 Secondary biliary cirrhosis
0.000 0.596 0.404
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.596 0.404
K25.0 Acute with haemorrhage
0.000 0.596 0.404
K74.1 Hepatic sclerosis
0.000 0.598 0.402
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.606 0.394
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.606 0.394
K70.0 Alcoholic fatty liver
0.000 0.608 0.392
K80.4 Calculus of bile duct with cholecystitis
0.000 0.608 0.392
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.612 0.388
K70.4 Alcoholic hepatic failure
0.000 0.618 0.382
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.618 0.382
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.623 0.377
I11 Hypertensive heart disease
0.000 0.626 0.374
I82.0 Budd-Chiari syndrome
0.000 0.628 0.372
I26 Pulmonary embolism
0.000 0.628 0.372
I15.1 Hypertension secondary to other renal disorders
0.000 0.629 0.371
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.629 0.370
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.629 0.370
I28 Other diseases of pulmonary vessels
0.000 0.631 0.369
I00-I02 Acute rheumatic fever
0.000 0.634 0.366
I86 Varicose veins of other sites
0.000 0.634 0.366
I15.8 Other secondary hypertension
0.000 0.634 0.366
I15.2 Hypertension secondary to endocrine disorders
0.000 0.634 0.366
K70.1 Alcoholic hepatitis
0.000 0.635 0.365
I81 Portal vein thrombosis
0.000 0.637 0.363
I82.2 Embolism and thrombosis of vena cava
0.000 0.645 0.355
I82.1 Thrombophlebitis migrans
0.000 0.651 0.349
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.652 0.348
K85.8 Other acute pancreatitis
0.000 0.652 0.348
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.652 0.348
K76.1 Chronic passive congestion of liver
0.000 0.657 0.343
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.662 0.338
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.662 0.338
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.662 0.338
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.662 0.338
K76.5 Hepatic veno-occlusive disease
0.000 0.669 0.331
K76.4 Peliosis hepatis
0.000 0.669 0.331
K76.3 Infarction of liver
0.000 0.669 0.331
K76.2 Central haemorrhagic necrosis of liver
0.000 0.669 0.331
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.669 0.331
I15.0 Renovascular hypertension
0.000 0.671 0.329
K91.4 Colostomy and enterostomy malfunction
0.000 0.674 0.326
K25.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.675 0.325
I82.3 Embolism and thrombosis of renal vein
0.000 0.682 0.318
I28.8 Other specified diseases of pulmonary vessels
0.000 0.682 0.318
K91.1 Postgastric surgery syndromes
0.000 0.688 0.312
K91.5 Postcholecystectomy syndrome
0.000 0.689 0.311
K76.7 Hepatorenal syndrome
0.000 0.691 0.309
K71.0 Toxic liver disease with cholestasis
0.000 0.691 0.309
I87.0 Postphlebitic syndrome
0.000 0.692 0.308
K72.9 Hepatic failure, unspecified
0.000 0.693 0.307
K71.9 Toxic liver disease, unspecified
0.000 0.695 0.305
K71.8 Toxic liver disease with other disorders of liver
0.000 0.695 0.305
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.695 0.305
K71.5 Toxic liver disease with chronic active hepatitis
0.000 0.695 0.305
K71.4 Toxic liver disease with chronic lobular hepatitis
0.000 0.695 0.305
K71.3 Toxic liver disease with chronic persistent hepatitis
0.000 0.695 0.305
K71.2 Toxic liver disease with acute hepatitis
0.000 0.695 0.305
K76.0 Fatty (change of) liver, not elsewhere classified
0.000 0.698 0.302
I86.4 Gastric varices
0.000 0.705 0.295
K85.1 Biliary acute pancreatitis
0.000 0.707 0.293
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.708 0.292
K85.3 Drug-induced acute pancreatitis
0.000 0.709 0.291
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.709 0.291
K91.3 Postoperative intestinal obstruction
0.000 0.710 0.290
K50.8 Other Crohn's disease
0.000 0.711 0.289
K29.6 Other gastritis
0.000 0.711 0.289
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.711 0.289
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.713 0.287
I12 Hypertensive renal disease
0.000 0.717 0.283
K85.9 Acute pancreatitis, unspecified
0.000 0.717 0.283
K85.0 Idiopathic acute pancreatitis
0.000 0.719 0.281
I87.9 Disorder of vein, unspecified
0.000 0.722 0.277
K83.8 Other specified diseases of biliary tract
0.000 0.728 0.272
K76.6 Portal hypertension
0.000 0.729 0.271
K71.1 Toxic liver disease with hepatic necrosis
0.000 0.733 0.267
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.735 0.265
K50.9 Crohn's disease, unspecified
0.000 0.735 0.265
I28.1 Aneurysm of pulmonary artery
0.000 0.736 0.264
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.736 0.264
I02 Rheumatic chorea
0.000 0.737 0.263
I01 Rheumatic fever with heart involvement
0.000 0.737 0.263
I86.0 Sublingual varices
0.000 0.737 0.263
I71 Aortic aneurysm and dissection
0.000 0.738 0.262
I86.8 Varicose veins of other specified sites
0.000 0.739 0.261
I86.2 Pelvic varices
0.000 0.740 0.260
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.740 0.260
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.000 0.741 0.259
K72.0 Acute and subacute hepatic failure
0.000 0.744 0.256
I82.8 Embolism and thrombosis of other specified veins
0.000 0.746 0.254
K66.1 Haemoperitoneum
0.003 0.747 0.250
I72 Other aneurysm
0.000 0.749 0.251
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.750 0.250
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.750 0.250
K93.1 Megacolon in Chagas' disease
0.000 0.750 0.250
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.750 0.250
K74.3 Primary biliary cirrhosis
0.000 0.752 0.248
K72.1 Chronic hepatic failure
0.000 0.752 0.247
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.757 0.243
I86.3 Vulval varices
0.000 0.757 0.242
K40-K46 Hernia
0.000 0.761 0.239
I00 Rheumatic fever without mention of heart involvement
0.000 0.770 0.229
I87.1 Compression of vein
0.000 0.774 0.226
K35-K38 Diseases of appendix
0.000 0.777 0.223
I70 Atherosclerosis
0.000 0.779 0.221
I60-I69 Cerebrovascular diseases
0.000 0.780 0.220
I74 Arterial embolism and thrombosis
0.000 0.783 0.217
I72.4 Aneurysm of artery of lower extremity
0.000 0.785 0.215
K76.9 Liver disease, unspecified
0.000 0.785 0.215
I89.1 Lymphangitis
0.000 0.786 0.214
K41 Femoral hernia
0.000 0.792 0.208
I72.9 Aneurysm of unspecified site
0.000 0.794 0.206
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.795 0.205
I61 Intracerebral haemorrhage
0.000 0.797 0.203
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.000 0.797 0.203
K85.2 Alcohol-induced acute pancreatitis
0.001 0.798 0.201
I63 Cerebral infarction
0.000 0.799 0.201
K50.0 Crohn's disease of small intestine
0.000 0.800 0.200
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.801 0.199
I12.9 Hypertensive renal disease without renal failure
0.000 0.801 0.199
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.803 0.197
I87.8 Other specified disorders of veins
0.000 0.804 0.196
K75 Other inflammatory liver diseases
0.000 0.805 0.195
K43 Ventral hernia
0.000 0.806 0.194
I72.0 Aneurysm of carotid artery
0.000 0.806 0.194
I72.2 Aneurysm of renal artery
0.000 0.806 0.193
K91.2 Postsurgical malabsorption, not elsewhere classified
0.001 0.807 0.192
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.808 0.192
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.811 0.188
I01.8 Other acute rheumatic heart disease
0.000 0.811 0.188
I01.2 Acute rheumatic myocarditis
0.000 0.811 0.188
I01.1 Acute rheumatic endocarditis
0.000 0.811 0.188
I01.0 Acute rheumatic pericarditis
0.000 0.811 0.188
I02.9 Rheumatic chorea without heart involvement
0.000 0.811 0.188
I02.0 Rheumatic chorea with heart involvement
0.000 0.811 0.188
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.812 0.188
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.812 0.188
I70.0 Atherosclerosis of aorta
0.000 0.813 0.187
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.820 0.180
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.820 0.180
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.820 0.180
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.820 0.180
I89.0 Lymphoedema, not elsewhere classified
0.000 0.827 0.173
K43.9 Ventral hernia without obstruction or gangrene
0.000 0.828 0.172
K21 Gastro-oesophageal reflux disease
0.000 0.828 0.172
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.828 0.172
K75.0 Abscess of liver
0.000 0.828 0.172
I72.8 Aneurysm of other specified arteries
0.000 0.829 0.171
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.830 0.170
I70.1 Atherosclerosis of renal artery
0.000 0.830 0.170
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.832 0.168
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.832 0.168
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.833 0.167
K46 Unspecified abdominal hernia
0.000 0.833 0.166
I74.5 Embolism and thrombosis of iliac artery
0.000 0.835 0.165
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.837 0.163
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.837 0.163
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.837 0.163
I72.3 Aneurysm of iliac artery
0.000 0.837 0.162
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.841 0.159
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.841 0.158
I61.8 Other intracerebral haemorrhage
0.000 0.842 0.158
I70.9 Generalised and unspecified atherosclerosis
0.000 0.842 0.158
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.842 0.158
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.842 0.158
I72.1 Aneurysm of artery of upper extremity
0.000 0.843 0.156
I05-I09 Chronic rheumatic heart diseases
0.000 0.844 0.156
I27 Other pulmonary heart diseases
0.000 0.844 0.156
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.845 0.155
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.846 0.153
I60 Subarachnoid haemorrhage
0.000 0.850 0.150
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.000 0.850 0.150
K41.1 Bilateral femoral hernia, with gangrene
0.000 0.850 0.149
K41.0 Bilateral femoral hernia, with obstruction, without gangrene
0.000 0.850 0.149
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.851 0.149
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.851 0.149
K90 Intestinal malabsorption
0.000 0.851 0.149
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.852 0.148
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.854 0.146
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.854 0.146
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.855 0.145
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.856 0.144
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.856 0.144
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.856 0.144
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.856 0.143
I27.9 Pulmonary heart disease, unspecified
0.000 0.857 0.143
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.857 0.143
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.857 0.143
I98.0 Cardiovascular syphilis
0.000 0.857 0.143
I71.0 Dissection of aorta [any part]
0.000 0.857 0.142
K36 Other appendicitis
0.000 0.860 0.140
K75.2 Nonspecific reactive hepatitis
0.000 0.860 0.140
K75.1 Phlebitis of portal vein
0.000 0.860 0.140
K43.7 Other and unspecified ventral hernia with gangrene
0.000 0.860 0.139
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.000 0.860 0.139
K43.5 Parastomal hernia without obstruction or gangrene
0.000 0.860 0.139
K43.4 Parastomal hernia with gangrene
0.000 0.860 0.139
K43.3 Parastomal hernia with obstruction, without gangrene
0.000 0.860 0.139
K43.2 Incisional hernia without obstruction or gangrene
0.000 0.860 0.139
K43.1 Ventral hernia with gangrene
0.000 0.860 0.139
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.861 0.139
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.861 0.139
I63.9 Cerebral infarction, unspecified
0.000 0.863 0.137
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.864 0.136
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.864 0.136
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.866 0.134
I62 Other nontraumatic intracranial haemorrhage
0.000 0.867 0.133
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.867 0.133
I70.8 Atherosclerosis of other arteries
0.000 0.868 0.132
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.868 0.132
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.868 0.132
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.868 0.132
K45 Other abdominal hernia
0.000 0.869 0.131
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.869 0.130
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.870 0.130
I99 Other and unspecified disorders of circulatory system
0.000 0.874 0.126
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.000 0.874 0.126
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.876 0.124
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.876 0.124
K52 Other non-infective gastro-enteritis and colitis
0.000 0.877 0.123
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.878 0.122
I11.9 Hypertensive heart disease without (congestive) heart failure
0.001 0.879 0.120
I65.1 Occlusion and stenosis of basilar artery
0.000 0.880 0.120
K46.1 Unspecified abdominal hernia with gangrene
0.000 0.880 0.119
K35 Acute appendicitis
0.000 0.882 0.118
I07 Rheumatic tricuspid valve diseases
0.000 0.883 0.117
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.883 0.117
K43.0 Ventral hernia with obstruction, without gangrene
0.000 0.885 0.115
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.886 0.114
I79.1 Aortitis in diseases classified elsewhere
0.000 0.886 0.114
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.886 0.114
K44 Diaphragmatic hernia
0.000 0.886 0.114
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.886 0.114
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.886 0.114
K41.2 Bilateral femoral hernia, without obstruction or gangrene
0.000 0.886 0.113
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.886 0.114
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.886 0.114
I73 Other peripheral vascular diseases
0.000 0.886 0.114
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.887 0.113
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.887 0.112
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.888 0.112
I27.1 Kyphoscoliotic heart disease
0.000 0.888 0.112
I78 Diseases of capillaries
0.000 0.888 0.112
I77 Other disorders of arteries and arterioles
0.000 0.888 0.112
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.889 0.111
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.889 0.111
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.891 0.108
K38 Other diseases of appendix
0.000 0.892 0.108
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.892 0.108
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.892 0.108
K92 Other diseases of digestive system
0.000 0.892 0.108
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.893 0.107
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.893 0.107
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.893 0.107
K90.3 Pancreatic steatorrhoea
0.000 0.893 0.107
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.893 0.107
K90.1 Tropical sprue
0.000 0.893 0.107
I06 Rheumatic aortic valve diseases
0.000 0.893 0.107
K46.0 Unspecified abdominal hernia with obstruction, without gangrene
0.000 0.893 0.106
I62.1 Nontraumatic extradural haemorrhage
0.000 0.895 0.105
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.895 0.105
I95 Hypotension
0.000 0.895 0.105
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.896 0.104
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.896 0.104
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.896 0.104
I09 Other rheumatic heart diseases
0.000 0.896 0.104
K90.8 Other intestinal malabsorption
0.000 0.897 0.102
N80.0 Endometriosis of uterus
0.000 0.899 0.101
K35.2 Acute appendicitis with generalized peritonitis
0.000 0.899 0.101
K52.3 Indeterminate colitis
0.000 0.901 0.099
I68.0 Cerebral amyloid angiopathy
0.000 0.901 0.099
K81 Cholecystitis
0.000 0.901 0.099
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.902 0.098
I69 Sequelae of cerebrovascular disease
0.000 0.903 0.097
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.903 0.097
I97.0 Postcardiotomy syndrome
0.000 0.904 0.096
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.905 0.095
K45.1 Other specified abdominal hernia with gangrene
0.000 0.906 0.094
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.000 0.906 0.094
I63.8 Other cerebral infarction
0.000 0.906 0.094
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.906 0.094
K45.8 Other specified abdominal hernia without obstruction or gangrene
0.000 0.906 0.094
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.907 0.093
I77.8 Other specified disorders of arteries and arterioles
0.000 0.907 0.093
K86 Other diseases of pancreas
0.000 0.910 0.090
I86.1 Scrotal varices
0.000 0.910 0.089
I60.8 Other subarachnoid haemorrhage
0.000 0.910 0.089
I07.1 Tricuspid insufficiency
0.000 0.911 0.089
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.000 0.911 0.089
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.911 0.088
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.912 0.088
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.914 0.086
I97.1 Other functional disturbances following cardiac surgery
0.000 0.914 0.086
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.914 0.086
I69.3 Sequelae of cerebral infarction
0.000 0.914 0.086
K92.0 Haematemesis
0.000 0.914 0.086
K35.1 Acute appendicitis with peritoneal abscess
0.000 0.915 0.085
K52.1 Toxic gastro-enteritis and colitis
0.000 0.915 0.085
K37 Unspecified appendicitis
0.000 0.915 0.084
I07.9 Tricuspid valve disease, unspecified
0.000 0.916 0.084
I07.8 Other tricuspid valve diseases
0.000 0.916 0.084
I07.2 Tricuspid stenosis with insufficiency
0.000 0.916 0.084
I07.0 Tricuspid stenosis
0.000 0.916 0.084
I95.2 Hypotension due to drugs
0.000 0.916 0.084
K35.0 Acute appendicitis with generalised peritonitis
0.000 0.917 0.083
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.917 0.083
I95.0 Idiopathic hypotension
0.000 0.917 0.083
I77.6 Arteritis, unspecified
0.000 0.917 0.083
I73.8 Other specified peripheral vascular diseases
0.000 0.917 0.083
K35.8 Acute appendicitis, other and unspecified
0.000 0.918 0.082
K75.4 Autoimmune hepatitis
0.000 0.918 0.082
I05 Rheumatic mitral valve diseases
0.000 0.919 0.081
I74.8 Embolism and thrombosis of other arteries
0.001 0.919 0.080
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.920 0.080
I77.5 Necrosis of artery
0.000 0.920 0.080
I77.4 Coeliac artery compression syndrome
0.000 0.920 0.080
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.920 0.080
I78.8 Other diseases of capillaries
0.000 0.920 0.080
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.921 0.079
I27.8 Other specified pulmonary heart diseases
0.000 0.921 0.079
K38.0 Hyperplasia of appendix
0.000 0.921 0.079
I06.0 Rheumatic aortic stenosis
0.000 0.921 0.079
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.922 0.078
K38.3 Fistula of appendix
0.000 0.922 0.078
I77.3 Arterial fibromuscular dysplasia
0.000 0.923 0.077
I78.9 Disease of capillaries, unspecified
0.000 0.923 0.077
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.923 0.077
I06.8 Other rheumatic aortic valve diseases
0.000 0.923 0.077
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.923 0.077
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.924 0.076
K38.1 Appendicular concretions
0.000 0.924 0.076
I09.8 Other specified rheumatic heart diseases
0.000 0.925 0.075
I09.2 Chronic rheumatic pericarditis
0.000 0.925 0.075
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.925 0.075
I09.0 Rheumatic myocarditis
0.000 0.925 0.075
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.926 0.074
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.926 0.073
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.000 0.927 0.073
K44.1 Diaphragmatic hernia with gangrene
0.000 0.927 0.073
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.927 0.073
I06.1 Rheumatic aortic insufficiency
0.000 0.927 0.072

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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