TreeWAS – Variant ID: rs515135

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	0.000	0.000	1.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.577	0.423
E78.2 Mixed hyperlipidaemia	0.000	0.613	0.387
E78.5 Hyperlipidaemia, unspecified	0.000	0.682	0.318
E78.6 Lipoprotein deficiency	0.000	0.688	0.312
E78.3 Hyperchylomicronaemia	0.000	0.696	0.303
E78.4 Other hyperlipidaemia	0.000	0.708	0.292
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.742	0.258
E78.8 Other disorders of lipoprotein metabolism	0.000	0.764	0.236
E78.1 Pure hyperglyceridaemia	0.000	0.773	0.227
Z95.1 Presence of aortocoronary bypass graft	0.000	0.935	0.065
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.973	0.027
I44.7 Left bundle-branch block, unspecified	0.000	0.973	0.027
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.978	0.022
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.982	0.018
C85.1 B-cell lymphoma, unspecified	0.000	0.985	0.015
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.985	0.015
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.000	0.987	0.013
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.000	0.987	0.013
C85.0 Lymphosarcoma	0.000	0.987	0.013
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.987	0.013
C85.7 Other specified types of non-Hodgkin's lymphoma	0.000	0.987	0.013
C84 Peripheral and cutaneous T-cell lymphomas	0.000	0.987	0.013
C91 Lymphoid leukaemia	0.000	0.988	0.012
C84.4 Peripheral T-cell lymphoma	0.000	0.989	0.011
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.989	0.011
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.989	0.011
C84.5 Other and unspecified T-cell lymphomas	0.000	0.989	0.011
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.989	0.011
C82.0 Small cleaved cell, follicular	0.000	0.990	0.010
C91.0 Acute lymphoblastic leukaemia	0.000	0.990	0.010
C91.1 Chronic lymphocytic leukaemia	0.000	0.990	0.010
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.990	0.010
C94 Other leukaemias of specified cell type	0.000	0.990	0.010
C93 Monocytic leukaemia	0.000	0.990	0.010
C86 Other specified types of T/NK-cell lymphoma	0.000	0.990	0.010
C82.3 Follicular lymphoma grade IIIa	0.000	0.990	0.010
C82.6 Cutaneous follicle centre lymphoma	0.000	0.991	0.009
C82.5 Diffuse follicle centre lymphoma	0.000	0.991	0.009
C82.4 Follicular lymphoma grade IIIb	0.000	0.991	0.009
C91.9 Lymphoid leukaemia, unspecified	0.000	0.991	0.009
C84.9 Mature T/NK-cell lymphoma, unspecified	0.000	0.991	0.009
C84.8 Cutaneous T-cell lymphoma, unspecified	0.000	0.991	0.009
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.000	0.991	0.009
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.000	0.991	0.009
C84.3 Lymphoepithelioid lymphoma	0.000	0.991	0.009
C84.2 T-zone lymphoma	0.000	0.991	0.009
C84.1 Sezary's diease	0.000	0.991	0.009
C81 Hodgkin's disease	0.000	0.991	0.009
C95 Leukaemia of unspecified cell type	0.000	0.991	0.009
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.009	0.991	0.000
C88 Malignant immunoproliferative diseases	0.000	0.991	0.009
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.991	0.009
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.991	0.009
C82.2 Large cell, follicular	0.000	0.991	0.009
C91.8 Mature B-cell leukaemia Burkitt-type	0.000	0.991	0.009
C91.7 Other lymphoid leukaemia	0.000	0.991	0.009
C91.6 Prolymphocytic leukaemia of T-cell type	0.000	0.991	0.009
C91.3 Prolymphocytic leukaemia	0.000	0.991	0.009
C91.2 Subacute lymphocytic leukaemia	0.000	0.991	0.009
C91.5 Adult T-cell leukaemia	0.000	0.992	0.008
C84.0 Mycosis fungoides	0.000	0.992	0.008
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.992	0.008
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.000	0.992	0.008
S30 Superficial injury of abdomen, lower back and pelvis	0.000	0.992	0.008
S30.0 Contusion of lower back and pelvis	0.000	0.992	0.008
S82.80 Fractures of other parts of lower leg (closed)	0.000	0.992	0.008
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.000	0.993	0.007
C86.5 Angioimmunoblastic T-cell lymphoma	0.000	0.993	0.007
C86.4 Blastic NK-cell lymphoma	0.000	0.993	0.007
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.000	0.993	0.007
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.000	0.993	0.007
C86.1 Hepatosplenic T-cell lymphoma	0.000	0.993	0.007
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.000	0.993	0.007
C93.9 Monocytic leukaemia, unspecified	0.000	0.993	0.007
C93.7 Other monocytic leukaemia	0.000	0.993	0.007
C93.3 Juvenile myelomonocytic leukaemia	0.000	0.993	0.007
C93.2 Subacute monocytic leukaemia	0.000	0.993	0.007
C93.1 Chronic monocytic leukaemia	0.000	0.993	0.007
C93.0 Acute monocytic leukaemia	0.000	0.993	0.007
C94.7 Other specified leukaemias	0.000	0.993	0.007
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.000	0.993	0.007
C94.5 Acute myelofibrosis	0.000	0.993	0.007
C94.4 Acute panmyelosis	0.000	0.993	0.007
C94.3 Mast cell leukaemia	0.000	0.993	0.007
C94.2 Acute megakaryoblastic leukaemia	0.000	0.993	0.007
C94.1 Chronic erythraemia	0.000	0.993	0.007
C94.0 Acute erythraemia and erythroleukaemia	0.000	0.993	0.007
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.993	0.007
C96.8 Histiocytic sarcoma	0.000	0.993	0.007
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.993	0.007
C96.6 Unifocal Langerhans-cell histiocytosis	0.000	0.993	0.007
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.000	0.993	0.007
C96.4 Sarcoma of dendritic cells (accessory cells)	0.000	0.993	0.007
C96.3 True histiocytic lymphoma	0.000	0.993	0.007
C96.2 Malignant mast cell tumour	0.000	0.993	0.007
C96.1 Malignant histiocytosis	0.000	0.993	0.007
C96.0 Letterer-Siwe disease	0.000	0.993	0.007
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.000	0.993	0.007
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.007	0.993	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.993	0.007
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.000	0.993	0.007
M22.4 Chondromalacia patellae	0.007	0.993	0.000
C95.9 Leukaemia, unspecified	0.000	0.993	0.007
C83.1 Small cleaved cell (diffuse)	0.000	0.993	0.007
C90.2 Plasmacytoma, extramedullary	0.000	0.993	0.007
C92 Myeloid leukaemia	0.000	0.993	0.007
C81.7 Other Hodgkin's disease	0.000	0.993	0.007
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.000	0.993	0.007
C81.3 Lymphocytic depletion	0.000	0.993	0.007
C81.2 Mixed cellularity	0.000	0.993	0.007
C81.0 Lymphocytic predominance	0.000	0.993	0.007
C91.4 Hairy-cell leukaemia	0.000	0.993	0.007
C95.7 Other leukaemia of unspecified cell type	0.000	0.993	0.007
C95.2 Subacute leukaemia of unspecified cell type	0.000	0.993	0.007
C95.1 Chronic leukaemia of unspecified cell type	0.000	0.993	0.007
C81.9 Hodgkin's disease, unspecified	0.000	0.993	0.007
C88.9 Malignant immunoproliferative disease, unspecified	0.000	0.993	0.007
C88.7 Other malignant immunoproliferative diseases	0.000	0.993	0.007
C88.3 Immunoproliferative small intestinal disease	0.000	0.993	0.007
C88.2 Gamma heavy chain disease	0.000	0.993	0.007
C88.1 Alpha heavy chain disease	0.000	0.993	0.007
C83.6 Undifferentiated (diffuse)	0.000	0.993	0.006
C83.5 Lymphoblastic (diffuse)	0.000	0.993	0.006
C83.4 Immunoblastic (diffuse)	0.000	0.993	0.006
C83.2 Mixed small and large cell (diffuse)	0.000	0.993	0.006
S30.2 Contusion of external genital organs	0.000	0.993	0.007
M22 Disorders of patella	0.007	0.993	0.000
C81.1 Nodular sclerosis	0.000	0.994	0.006
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.000	0.994	0.006
C83.7 Burkitt's tumour	0.000	0.994	0.006
M22.8 Other disorders of patella	0.006	0.994	0.000
C90.3 Solitary plasmacytoma	0.000	0.994	0.006
S30.1 Contusion of abdominal wall	0.000	0.994	0.006
C95.0 Acute leukaemia of unspecified cell type	0.000	0.994	0.006
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.000	0.994	0.006
M22.3 Other derangements of patella	0.006	0.994	0.000
M22.2 Patellofemoral disorders	0.006	0.994	0.000
C83.0 Small cell (diffuse)	0.000	0.994	0.005
C90.1 Plasma cell leukaemia	0.000	0.995	0.005
Z95.3 Presence of xenogenic heart valve	0.000	0.995	0.005
M22.9 Disorder of patella, unspecified	0.005	0.995	0.000
C92.9 Myeloid leukaemia, unspecified	0.000	0.995	0.005
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.000	0.995	0.005
C92.7 Other myeloid leukaemia	0.000	0.995	0.005
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.000	0.995	0.005
C92.5 Acute myelomonocytic leukaemia	0.000	0.995	0.005
C92.4 Acute promyelocytic leukaemia	0.000	0.995	0.005
C92.3 Myeloid sarcoma	0.000	0.995	0.005
C92.2 Subacute myeloid leukaemia	0.000	0.995	0.005
C88.0 Waldenstrom's macroglobulinaemia	0.000	0.995	0.005
N39.8 Other specified disorders of urinary system	0.005	0.995	0.000
C83.3 Large cell (diffuse)	0.000	0.995	0.005
I80 Phlebitis and thrombophlebitis	0.005	0.995	0.000
C92.1 Chronic myeloid leukaemia	0.000	0.995	0.005
M22.1 Recurrent subluxation of patella	0.005	0.995	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.005	0.995	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.005	0.995	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.995	0.005
C90.0 Multiple myeloma	0.000	0.995	0.005
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.995	0.005
E46 Unspecified protein-energy malnutrition	0.005	0.995	0.000
M22.0 Recurrent dislocation of patella	0.004	0.995	0.000
K62.9 Disease of anus and rectum, unspecified	0.000	0.996	0.004
K86.2 Cyst of pancreas	0.000	0.996	0.004
I34.0 Mitral (valve) insufficiency	0.004	0.996	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.004	0.996	0.000
Z34.8 Supervision of other normal pregnancy	0.004	0.996	0.000
M22.10 Recurrent subluxation of patella, unspecified knee	0.004	0.996	0.000
Z94.0 Kidney transplant status	0.000	0.996	0.004
Z87.8 Personal history of other specified conditions	0.000	0.996	0.004
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.996	0.004
H00.1 Chalazion	0.003	0.997	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.003	0.997	0.000
K86 Other diseases of pancreas	0.000	0.997	0.003
E27.1 Primary adrenocortical insufficiency	0.003	0.997	0.000
I25.1 Atherosclerotic heart disease	0.000	0.997	0.003
H02.9 Disorder of eyelid, unspecified	0.000	0.997	0.003
E27 Other disorders of adrenal gland	0.003	0.997	0.000
E27.2 Addisonian crisis	0.003	0.997	0.000
H00.0 Hordeolum and other deep inflammation of eyelid	0.003	0.997	0.000
K86.9 Disease of pancreas, unspecified	0.000	0.997	0.003
S82.8 Fractures of other parts of lower leg	0.000	0.997	0.003
K86.1 Other chronic pancreatitis	0.000	0.997	0.003
F33.9 Recurrent depressive disorder, unspecified	0.000	0.997	0.003
E27.9 Disorder of adrenal gland, unspecified	0.003	0.997	0.000
F33 Recurrent depressive disorder	0.000	0.997	0.003
Z34 Supervision of normal pregnancy	0.003	0.997	0.000
Z34.0 Supervision of normal first pregnancy	0.003	0.997	0.000
I34.1 Mitral (valve) prolapse	0.003	0.997	0.000
I34 Nonrheumatic mitral valve disorders	0.003	0.997	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.003	0.997	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.003	0.997	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.003	0.997	0.000
J98.4 Other disorders of lung	0.000	0.997	0.003
H00 Hordeolum and chalazion	0.003	0.997	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.997	0.003
G93.9 Disorder of brain, unspecified	0.003	0.997	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.003	0.997	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.003	0.997	0.000
E27.5 Adrenomedullary hyperfunction	0.003	0.997	0.000
E27.0 Other adrenocortical overactivity	0.003	0.997	0.000
E27.8 Other specified disorders of adrenal gland	0.003	0.997	0.000
L60.8 Other nail disorders	0.003	0.997	0.000
G93 Other disorders of brain	0.003	0.997	0.000
S43.0 Dislocation of shoulder joint	0.003	0.997	0.000
G93.8 Other specified disorders of brain	0.003	0.997	0.000
S82.40 Fracture of fibula alone (closed)	0.000	0.997	0.003
C92.0 Acute myeloid leukaemia	0.000	0.997	0.002
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.997	0.002
G93.0 Cerebral cysts	0.003	0.997	0.000
S82.86 Maisonneuve's fracture	0.000	0.997	0.002
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.997	0.002
I34.8 Other nonrheumatic mitral valve disorders	0.002	0.997	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.002	0.998	0.000
G93.5 Compression of brain	0.002	0.998	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.002	0.998	0.000
F33.8 Other recurrent depressive disorders	0.000	0.998	0.002
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.998	0.002
G93.6 Cerebral oedema	0.002	0.998	0.000
G12.2 Motor neuron disease	0.002	0.998	0.000
Z94 Transplanted organ and tissue status	0.000	0.998	0.002
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
M24.6 Ankylosis of joint	0.002	0.998	0.000
X78.0 Home	0.000	0.998	0.002
G93.3 Postviral fatigue syndrome	0.002	0.998	0.000
I22.8 Subsequent myocardial infarction of other sites	0.000	0.998	0.002
K09.0 Developmental odontogenic cysts	0.000	0.998	0.002
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.002	0.998	0.000
G93.7 Reye's syndrome	0.002	0.998	0.000
Z94.2 Lung transplant status	0.000	0.998	0.002
I44 Atrioventricular and left bundle-branch block	0.000	0.998	0.002
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.002	0.998	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.002	0.998	0.000
E40-E46 Malnutrition	0.002	0.998	0.000
S52.80 Fracture of other parts of forearm (closed)	0.000	0.998	0.002
S92.20 Fracture of other tarsal bone(s) (closed)	0.002	0.998	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.000	0.998	0.002
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.000	0.998	0.002
N36.8 Other specified disorders of urethra	0.000	0.998	0.002
M24.64 Ankylosis of joint (Hand)	0.002	0.998	0.000
G93.2 Benign intracranial hypertension	0.002	0.998	0.000
I44.6 Other and unspecified fascicular block	0.000	0.998	0.002
Z94.1 Heart transplant status	0.000	0.998	0.002
Z94.7 Corneal transplant status	0.000	0.998	0.002
K02.9 Dental caries, unspecified	0.002	0.998	0.000
S92.0 Fracture of calcaneus	0.002	0.998	0.000
N41.1 Chronic prostatitis	0.002	0.998	0.000
Z97.4 Presence of external hearing-aid	0.002	0.998	0.000
Z94.9 Transplanted organ and tissue status, unspecified	0.000	0.998	0.002
Z94.6 Bone transplant status	0.000	0.998	0.002
Z94.5 Skin transplant status	0.000	0.998	0.002
Z94.3 Heart and lungs transplant status	0.000	0.998	0.002
S82.81 Fractures of other parts of lower leg (open)	0.000	0.998	0.002
E22.1 Hyperprolactinaemia	0.002	0.998	0.000
E20-E35 Disorders of other endocrine glands	0.002	0.998	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.002	0.998	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.002	0.998	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.002	0.998	0.000
M24.68 Ankylosis of joint (Other)	0.002	0.998	0.000
M24.66 Ankylosis of joint (Lower leg)	0.002	0.998	0.000
M24.63 Ankylosis of joint (Forearm)	0.002	0.998	0.000
M24.62 Ankylosis of joint (Upper arm)	0.002	0.998	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.002	0.998	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.002	0.998	0.000
B18.1 Chronic viral hepatitis B without delta-agent	0.000	0.998	0.002
E21.5 Disorder of parathyroid gland, unspecified	0.002	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
E26 Hyperaldosteronism	0.002	0.998	0.000
E22 Hyperfunction of pituitary gland	0.002	0.998	0.000
M25.74 Osteophyte (Hand)	0.002	0.998	0.000
S92.70 Multiple fractures of foot (closed)	0.002	0.998	0.000
N42.8 Other specified disorders of prostate	0.002	0.998	0.000
S31.1 Open wound of abdominal wall	0.000	0.998	0.002
Z11.5 Special screening examination for other viral diseases	0.002	0.998	0.000
Z94.8 Other transplanted organ and tissue status	0.000	0.998	0.002
I44.5 Left posterior fascicular block	0.000	0.998	0.002
C25.1 Body of pancreas	0.002	0.998	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.002	0.998	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.998	0.002
M24.56 Contracture of joint (Lower leg)	0.002	0.998	0.000
L60.3 Nail dystrophy	0.002	0.998	0.000
L73.2 Hidradenitis suppurativa	0.000	0.998	0.002
E26.9 Hyperaldosteronism, unspecified	0.002	0.998	0.000
M24.5 Contracture of joint	0.002	0.998	0.000
Z94.4 Liver transplant status	0.000	0.998	0.002
C25.9 Pancreas, unspecified	0.002	0.998	0.000
C25.3 Pancreatic duct	0.002	0.998	0.000
S82.4 Fracture of fibula alone	0.000	0.998	0.002
S92.7 Multiple fractures of foot	0.002	0.998	0.000
E24 Cushing's syndrome	0.002	0.998	0.000
S42.30 Fracture of shaft of humerus (closed)	0.000	0.998	0.002
C25.2 Tail of pancreas	0.002	0.998	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.002	0.998	0.000
E45 Retarded development following protein-energy malnutrition	0.002	0.998	0.000
E43 Unspecified severe protein-energy malnutrition	0.002	0.998	0.000
E42 Marasmic kwashiorkor	0.002	0.998	0.000
E41 Nutritional marasmus	0.002	0.998	0.000
E40 Kwashiorkor	0.002	0.998	0.000
L60.2 Onychogryphosis	0.002	0.998	0.000
E28.3 Primary ovarian failure	0.002	0.998	0.000
S50.9 Superficial injury of forearm, unspecified	0.000	0.998	0.002
Z11.4 Special screening examination for human immunodeficiency virus [HIV]	0.002	0.998	0.000
L60 Nail disorders	0.002	0.998	0.000
S92 Fracture of foot, except ankle	0.002	0.998	0.000
M31.3 Wegener's granulomatosis	0.002	0.998	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.002	0.998	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.000	0.998	0.002
M24.54 Contracture of joint (Hand)	0.002	0.998	0.000
S92.01 Fracture of calcaneus (open)	0.002	0.998	0.000
E24.9 Cushing's syndrome, unspecified	0.002	0.998	0.000
S50.0 Contusion of elbow	0.000	0.998	0.002
Z95.2 Presence of prosthetic heart valve	0.000	0.998	0.002
E28 Ovarian dysfunction	0.002	0.998	0.000
E21.0 Primary hyperparathyroidism	0.002	0.998	0.000
I44.1 Atrioventricular block, second degree	0.000	0.998	0.002
S31 Open wound of abdomen, lower back and pelvis	0.000	0.998	0.002
E26.0 Primary hyperaldosteronism	0.002	0.998	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.002	0.998	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.002	0.998	0.000
E32 Diseases of thymus	0.002	0.998	0.000
E31 Polyglandular dysfunction	0.002	0.998	0.000
E30 Disorders of puberty, not elsewhere classified	0.002	0.998	0.000
E25 Adrenogenital disorders	0.002	0.998	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.001	0.998	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.001	0.998	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.001	0.998	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.001	0.998	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.001	0.998	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.001	0.998	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.001	0.998	0.000
E21.4 Other specified disorders of parathyroid gland	0.002	0.998	0.000
E21.2 Other hyperparathyroidism	0.002	0.998	0.000
H10.9 Conjunctivitis, unspecified	0.002	0.998	0.000
T93.2 Sequelae of other fractures of lower limb	0.002	0.998	0.000
C25 Malignant neoplasm of pancreas	0.002	0.998	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.002	0.998	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.002	0.998	0.000
M24.51 Contracture of joint (Shoulder region)	0.002	0.998	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.001	0.998	0.000
S92.1 Fracture of talus	0.002	0.998	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.001	0.998	0.000
E22.8 Other hyperfunction of pituitary gland	0.001	0.998	0.000
E26.8 Other hyperaldosteronism	0.001	0.998	0.000
E26.1 Secondary hyperaldosteronism	0.001	0.998	0.000
H20.0 Acute and subacute iridocyclitis	0.002	0.998	0.000
I44.4 Left anterior fascicular block	0.000	0.998	0.001
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.002	0.998	0.000
M24 Other specific joint derangements	0.002	0.998	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.002	0.998	0.000
H20.8 Other iridocyclitis	0.002	0.998	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.002	0.998	0.000
E24.0 Pituitary-dependent Cushing's disease	0.001	0.998	0.000
S92.4 Fracture of great toe	0.001	0.998	0.000
M24.59 Contracture of joint (Site unspecified)	0.001	0.998	0.000
M24.58 Contracture of joint (Other)	0.001	0.998	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.001	0.998	0.000
M24.53 Contracture of joint (Forearm)	0.001	0.998	0.000
M24.52 Contracture of joint (Upper arm)	0.001	0.998	0.000
M24.50 Contracture of joint (Multiple sites)	0.001	0.998	0.000
S82.41 Fracture of fibula alone (open)	0.000	0.998	0.001
S92.10 Fracture of talus (closed)	0.001	0.998	0.000
S92.71 Multiple fractures of foot (open)	0.001	0.998	0.000
E24.8 Other Cushing's syndrome	0.001	0.998	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.001	0.998	0.000
E24.3 Ectopic ACTH syndrome	0.001	0.998	0.000
E24.1 Nelson's syndrome	0.001	0.998	0.000
E44.1 Mild protein-energy malnutrition	0.001	0.998	0.000
E44.0 Moderate protein-energy malnutrition	0.001	0.998	0.000
N48.6 Balanitis xerotica obliterans	0.002	0.998	0.000
Z11.1 Special screening examination for respiratory tuberculosis	0.002	0.998	0.000
E20 Hypoparathyroidism	0.001	0.998	0.000
K63.1 Perforation of intestine (nontraumatic)	0.002	0.998	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.002	0.998	0.000
Q76.0 Spina bifida occulta	0.001	0.998	0.000
M24.57 Contracture of joint (Ankle and foot)	0.001	0.998	0.000
C50.3 Lower-inner quadrant of breast	0.002	0.998	0.000
E21.3 Hyperparathyroidism, unspecified	0.002	0.998	0.000
G93.4 Encephalopathy, unspecified	0.001	0.998	0.000
L60.9 Nail disorder, unspecified	0.001	0.998	0.000
L60.5 Yellow nail syndrome	0.001	0.998	0.000
L60.4 Beau's lines	0.001	0.998	0.000
L60.1 Onycholysis	0.001	0.998	0.000
S92.9 Fracture of foot, unspecified	0.001	0.998	0.000
Z11.9 Special screening examination for infectious and parasitic diseases, unspecified	0.001	0.998	0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.002	0.998	0.000
S92.30 Fracture of metatarsal bone (closed)	0.000	0.998	0.001
K86.3 Pseudocyst of pancreas	0.000	0.998	0.001
S92.5 Fracture of other toe	0.001	0.998	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.000	0.998	0.001
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.000	0.998	0.001
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.000	0.998	0.001
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.000	0.998	0.001
S50 Superficial injury of forearm	0.000	0.998	0.001
E24.2 Drug-induced Cushing's syndrome	0.001	0.998	0.000
E28.9 Ovarian dysfunction, unspecified	0.001	0.998	0.000
E28.8 Other ovarian dysfunction	0.001	0.998	0.000
E28.1 Androgen excess	0.001	0.998	0.000
E28.0 Oestrogen excess	0.001	0.998	0.000
I44.3 Other and unspecified atrioventricular block	0.000	0.998	0.001
S31.0 Open wound of lower back and pelvis	0.000	0.998	0.001
L03.9 Cellulitis, unspecified	0.000	0.999	0.001
O90.8 Other complications of the puerperium, not elsewhere classified	0.001	0.999	0.000
R20.8 Other and unspecified disturbances of skin sensation	0.000	0.999	0.001
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.000	0.999	0.001
S31.5 Open wound of other and unspecified external genital organs	0.000	0.999	0.001
S31.3 Open wound of scrotum and testes	0.000	0.999	0.001
S31.2 Open wound of penis	0.000	0.999	0.001
C25.8 Overlapping lesion of pancreas	0.001	0.999	0.000
C25.7 Other parts of pancreas	0.001	0.999	0.000
C25.4 Endocrine pancreas	0.001	0.999	0.000
E25.9 Adrenogenital disorder, unspecified	0.001	0.999	0.000
E25.8 Other adrenogenital disorders	0.001	0.999	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.001	0.999	0.000
E30.9 Disorder of puberty, unspecified	0.001	0.999	0.000
E30.8 Other disorders of puberty	0.001	0.999	0.000
E30.1 Precocious puberty	0.001	0.999	0.000
E30.0 Delayed puberty	0.001	0.999	0.000
E31.9 Polyglandular dysfunction, unspecified	0.001	0.999	0.000
E31.8 Other polyglandular dysfunction	0.001	0.999	0.000
E31.1 Polyglandular hyperfunction	0.001	0.999	0.000
E31.0 Autoimmune polyglandular failure	0.001	0.999	0.000
E32.9 Disease of thymus, unspecified	0.001	0.999	0.000
E32.8 Other diseases of thymus	0.001	0.999	0.000
E32.1 Abscess of thymus	0.001	0.999	0.000
E32.0 Persistent hyperplasia of thymus	0.001	0.999	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.001	0.999	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.001	0.999	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.001	0.999	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.000	0.999	0.001
S92.3 Fracture of metatarsal bone	0.001	0.999	0.001
E34 Other endocrine disorders	0.001	0.999	0.000
E29 Testicular dysfunction	0.001	0.999	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.001	0.999	0.000
S92.11 Fracture of talus (open)	0.001	0.999	0.000
S92.41 Fracture of great toe (open)	0.001	0.999	0.000
E20.9 Hypoparathyroidism, unspecified	0.000	0.999	0.001
M24.9 Joint derangement, unspecified	0.001	0.999	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.001	0.999	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.001	0.999	0.000
M24.7 Protrusio acetabuli	0.001	0.999	0.000
Z95.4 Presence of other heart-valve replacement	0.000	0.999	0.001
S37 Injury of urinary and pelvic organs	0.000	0.999	0.001
S92.40 Fracture of great toe (closed)	0.001	0.999	0.000
S92.50 Fracture of other toe (closed)	0.001	0.999	0.000
T86.0 Bone-marrow transplant rejection	0.000	0.999	0.001
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.000	0.999	0.001
S50.1 Contusion of other and unspecified parts of forearm	0.000	0.999	0.001
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.999	0.001
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.001	0.999	0.000
T93 Sequelae of injuries of lower limb	0.001	0.999	0.000
E20.8 Other hypoparathyroidism	0.001	0.999	0.000
E20.1 Pseudohypoparathyroidism	0.001	0.999	0.000
E20.0 Idiopathic hypoparathyroidism	0.001	0.999	0.000
E34.8 Other specified endocrine disorders	0.001	0.999	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.001	0.999	0.000
S92.91 Fracture of foot, unspecified (open)	0.001	0.999	0.000
S92.90 Fracture of foot, unspecified (closed)	0.001	0.999	0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.000	0.999	0.001
Z31.9 Procreative management, unspecified	0.001	0.999	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.000	0.999	0.001
S33.7 Sprain and strain of other and unspecified parts of lumbar spine and pelvis	0.000	0.999	0.001
S33.6 Sprain and strain of sacro-iliac joint	0.000	0.999	0.001
S33.5 Sprain and strain of lumbar spine	0.000	0.999	0.001
S33.4 Traumatic rupture of symphysis pubis	0.000	0.999	0.001
S33.3 Dislocation of other and unspecified parts of lumbar spine and pelvis	0.000	0.999	0.001
S33.2 Dislocation of sacro-iliac and sacrococcygeal joint	0.000	0.999	0.001
S33.1 Dislocation of lumbar vertebra	0.000	0.999	0.001
S33.0 Traumatic rupture of lumbar intervertebral disk	0.000	0.999	0.001
S34.8 Injury of other and unspecified nerves at abdomen, lower back and pelvis level	0.000	0.999	0.001
S34.6 Injury of peripheral nerve(s) of abdomen, lower back and pelvis	0.000	0.999	0.001
S34.5 Injury of lumbar, sacral and pelvic sympathetic nerves	0.000	0.999	0.001
S34.4 Injury of lumbosacral plexus	0.000	0.999	0.001
S34.3 Injury of cauda equina	0.000	0.999	0.001
S34.2 Injury of nerve root of lumbar and sacral spine	0.000	0.999	0.001
S34.1 Other injury of lumbar spinal cord	0.000	0.999	0.001
S34.0 Concussion and oedema of lumbar spinal cord	0.000	0.999	0.001
S35.9 Injury of unspecified blood vessel at abdomen, lower back and pelvis level	0.000	0.999	0.001
S35.8 Injury of other blood vessels at abdomen, lower back and pelvis level	0.000	0.999	0.001
S35.7 Injury of multiple blood vessels at abdomen, lower back and pelvis level	0.000	0.999	0.001
S35.5 Injury of iliac blood vessels	0.000	0.999	0.001
S35.4 Injury of renal blood vessels	0.000	0.999	0.001
S35.3 Injury of portal or splenic vein	0.000	0.999	0.001
S35.2 Injury of coeliac or mesenteric artery	0.000	0.999	0.001
S35.1 Injury of inferior vena cava	0.000	0.999	0.001
S35.0 Injury of abdominal aorta	0.000	0.999	0.001
S38.3 Traumatic amputation of other and unspecified parts of abdomen, lower back and pelvis	0.000	0.999	0.001
S38.2 Traumatic amputation of external genital organs	0.000	0.999	0.001
S38.1 Crushing injury of other and unspecified parts of abdomen, lower back and pelvis	0.000	0.999	0.001
S38.0 Crushing injury of external genital organs	0.000	0.999	0.001
S50.7 Multiple superficial injuries of forearm	0.000	0.999	0.001
Q74 Other congenital malformations of limb(s)	0.001	0.999	0.000
Z11 Special screening examination for infectious and parasitic diseases	0.001	0.999	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.001	0.999	0.000
M24.0 Loose body in joint	0.001	0.999	0.000
G12 Spinal muscular atrophy and related syndromes	0.001	0.999	0.000
S92.31 Fracture of metatarsal bone (open)	0.001	0.999	0.001
E29.9 Testicular dysfunction, unspecified	0.001	0.999	0.000
E29.8 Other testicular dysfunction	0.001	0.999	0.000
E29.0 Testicular hyperfunction	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations