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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs516636
log Bayes Factor = 1.85041
Chromosome 1   position 177,855,517  (GRCh37) Explore rs516636 on Ensembl!
Variant rs516636 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E66.8 Other obesity
0.970 0.030 0.000
E66 Obesity
0.968 0.032 0.000
E65-E68 Obesity and other hyperalimentation
0.953 0.047 0.000
E66.9 Obesity, unspecified
0.940 0.060 0.000
E11 Non-insulin-dependent diabetes mellitus
0.935 0.065 0.000
E11.9 Without complications
0.933 0.067 0.000
E10-E14 Diabetes mellitus
0.924 0.076 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.923 0.077 0.000
E11.4 With neurological complications
0.900 0.100 0.000
E20-E35 Disorders of other endocrine glands
0.861 0.139 0.000
E27 Other disorders of adrenal gland
0.854 0.146 0.000
E65 Localised adiposity
0.851 0.149 0.000
E11.0 With coma
0.799 0.201 0.000
E22 Hyperfunction of pituitary gland
0.792 0.207 0.000
E27.2 Addisonian crisis
0.773 0.227 0.000
E27.1 Primary adrenocortical insufficiency
0.764 0.236 0.000
E11.2 With renal complications
0.740 0.260 0.000
E11.5 With peripheral circulatory complications
0.738 0.262 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.733 0.267 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.722 0.278 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.716 0.284 0.000
E11.8 With unspecified complications
0.712 0.288 0.000
E27.9 Disorder of adrenal gland, unspecified
0.711 0.289 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.702 0.298 0.000
E11.1 With ketoacidosis
0.698 0.302 0.000
E66.1 Drug-induced obesity
0.694 0.306 0.000
E10 Insulin-dependent diabetes mellitus
0.692 0.308 0.000
E66.0 Obesity due to excess calories
0.688 0.312 0.000
E67 Other hyperalimentation
0.683 0.317 0.000
E68 Sequelae of hyperalimentation
0.683 0.317 0.000
E22.0 Acromegaly and pituitary gigantism
0.678 0.322 0.000
E29 Testicular dysfunction
0.671 0.329 0.000
E11.7 With multiple complications
0.670 0.330 0.000
E12 Malnutrition-related diabetes mellitus
0.663 0.337 0.000
E27.8 Other specified disorders of adrenal gland
0.640 0.360 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.617 0.383 0.000
E32 Diseases of thymus
0.617 0.383 0.000
E31 Polyglandular dysfunction
0.617 0.383 0.000
E30 Disorders of puberty, not elsewhere classified
0.617 0.383 0.000
E25 Adrenogenital disorders
0.617 0.383 0.000
E27.5 Adrenomedullary hyperfunction
0.612 0.388 0.000
E27.0 Other adrenocortical overactivity
0.612 0.388 0.000
E10.6 With other specified complications
0.590 0.410 0.000
E00-E07 Disorders of thyroid gland
0.580 0.420 0.000
E13 Other specified diabetes mellitus
0.570 0.430 0.000
E20 Hypoparathyroidism
0.569 0.430 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.568 0.432 0.000
E22.8 Other hyperfunction of pituitary gland
0.568 0.432 0.000
E10.9 Without complications
0.558 0.442 0.000
E40-E46 Malnutrition
0.553 0.447 0.000
E10.1 With ketoacidosis
0.540 0.460 0.000
E10.0 With coma
0.539 0.461 0.000
E24 Cushing's syndrome
0.536 0.464 0.000
E29.1 Testicular hypofunction
0.535 0.465 0.000
E11.6 With other specified complications
0.523 0.476 0.000
E07 Other disorders of thyroid
0.510 0.490 0.000
E50-E64 Other nutritional deficiencies
0.498 0.502 0.000
E10.7 With multiple complications
0.496 0.504 0.000
E10.8 With unspecified complications
0.495 0.505 0.000
E67.8 Other specified hyperalimentation
0.490 0.510 0.000
E67.3 Hypervitaminosis D
0.490 0.510 0.000
E67.2 Megavitamin-B6 syndrome
0.490 0.510 0.000
E67.1 Hypercarotenaemia
0.490 0.510 0.000
E67.0 Hypervitaminosis A
0.490 0.510 0.000
E11.3 With ophthalmic complications
0.489 0.511 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.489 0.511 0.000
E10.2 With renal complications
0.488 0.512 0.000
E29.9 Testicular dysfunction, unspecified
0.481 0.519 0.000
E29.8 Other testicular dysfunction
0.481 0.519 0.000
E29.0 Testicular hyperfunction
0.481 0.519 0.000
E12.9 Without complications
0.475 0.525 0.000
E12.8 With unspecified complications
0.475 0.525 0.000
E12.7 With multiple complications
0.475 0.525 0.000
E12.6 With other specified complications
0.475 0.525 0.000
E12.5 With peripheral circulatory complications
0.475 0.525 0.000
E12.4 With neurological complications
0.475 0.525 0.000
E12.3 With ophthalmic complications
0.475 0.525 0.000
E12.2 With renal complications
0.475 0.525 0.000
E12.1 With ketoacidosis
0.475 0.525 0.000
E12.0 With coma
0.475 0.525 0.000
E26 Hyperaldosteronism
0.474 0.525 0.000
E28 Ovarian dysfunction
0.459 0.541 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.456 0.544 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.455 0.545 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.454 0.546 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.452 0.548 0.000
E10.5 With peripheral circulatory complications
0.451 0.549 0.000
L08 Other local infections of skin and subcutaneous tissue
0.449 0.551 0.000
E25.9 Adrenogenital disorder, unspecified
0.442 0.557 0.000
E25.8 Other adrenogenital disorders
0.442 0.557 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.442 0.557 0.000
E30.9 Disorder of puberty, unspecified
0.442 0.557 0.000
E30.8 Other disorders of puberty
0.442 0.557 0.000
E30.1 Precocious puberty
0.442 0.557 0.000
E30.0 Delayed puberty
0.442 0.557 0.000
E31.9 Polyglandular dysfunction, unspecified
0.442 0.557 0.000
E31.8 Other polyglandular dysfunction
0.442 0.557 0.000
E31.1 Polyglandular hyperfunction
0.442 0.557 0.000
E31.0 Autoimmune polyglandular failure
0.442 0.557 0.000
E32.9 Disease of thymus, unspecified
0.442 0.557 0.000
E32.8 Other diseases of thymus
0.442 0.557 0.000
E32.1 Abscess of thymus
0.442 0.557 0.000
E32.0 Persistent hyperplasia of thymus
0.442 0.557 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.442 0.557 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.442 0.557 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.442 0.557 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.439 0.561 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.439 0.561 0.000
E22.1 Hyperprolactinaemia
0.432 0.567 0.000
E07.9 Disorder of thyroid, unspecified
0.430 0.570 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.430 0.570 0.000
L03 Cellulitis
0.427 0.573 0.000
E10.4 With neurological complications
0.422 0.578 0.000
E07.8 Other specified disorders of thyroid
0.419 0.581 0.000
L08.8 Other specified local infections of skin and subcutaneous tissue
0.417 0.582 0.000
L03.3 Cellulitis of trunk
0.417 0.583 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.416 0.584 0.000
E00 Congenital iodine-deficiency syndrome
0.416 0.584 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.415 0.585 0.000
E03 Other hypothyroidism
0.414 0.586 0.000
E13.8 With unspecified complications
0.409 0.591 0.000
E13.7 With multiple complications
0.409 0.591 0.000
E13.6 With other specified complications
0.409 0.591 0.000
E13.5 With peripheral circulatory complications
0.409 0.591 0.000
E13.4 With neurological complications
0.409 0.591 0.000
E13.3 With ophthalmic complications
0.409 0.591 0.000
E13.2 With renal complications
0.409 0.591 0.000
E13.1 With ketoacidosis
0.409 0.591 0.000
E13.0 With coma
0.409 0.591 0.000
E20.8 Other hypoparathyroidism
0.408 0.591 0.000
E20.1 Pseudohypoparathyroidism
0.408 0.591 0.000
E20.0 Idiopathic hypoparathyroidism
0.408 0.591 0.000
E24.2 Drug-induced Cushing's syndrome
0.408 0.592 0.000
E05.9 Thyrotoxicosis, unspecified
0.402 0.598 0.000
E34 Other endocrine disorders
0.397 0.603 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.396 0.603 0.000
E45 Retarded development following protein-energy malnutrition
0.396 0.603 0.000
E43 Unspecified severe protein-energy malnutrition
0.396 0.603 0.000
E42 Marasmic kwashiorkor
0.396 0.603 0.000
E41 Nutritional marasmus
0.396 0.603 0.000
E40 Kwashiorkor
0.396 0.603 0.000
E51 Thiamine deficiency
0.396 0.604 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.389 0.611 0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.386 0.614 0.000
E24.8 Other Cushing's syndrome
0.384 0.616 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.384 0.616 0.000
E24.3 Ectopic ACTH syndrome
0.384 0.616 0.000
E24.1 Nelson's syndrome
0.384 0.616 0.000
E61 Deficiency of other nutrient elements
0.380 0.620 0.000
E23 Hypofunction and other disorders of pituitary gland
0.378 0.622 0.000
E24.0 Pituitary-dependent Cushing's disease
0.377 0.623 0.000
E07.1 Dyshormogenetic goitre
0.366 0.634 0.000
E07.0 Hypersecretion of calcitonin
0.366 0.634 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.365 0.635 0.000
L03.2 Cellulitis of face
0.361 0.639 0.000
E20.9 Hypoparathyroidism, unspecified
0.361 0.639 0.000
E58 Dietary calcium deficiency
0.360 0.639 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.357 0.643 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.357 0.643 0.000
E63 Other nutritional deficiencies
0.357 0.643 0.000
E56 Other vitamin deficiencies
0.357 0.643 0.000
E50 Vitamin A deficiency
0.357 0.643 0.000
E60 Dietary zinc deficiency
0.357 0.643 0.000
E59 Dietary selenium deficiency
0.357 0.643 0.000
E54 Ascorbic acid deficiency
0.357 0.643 0.000
E52 Niacin deficiency [pellagra]
0.357 0.643 0.000
E21.2 Other hyperparathyroidism
0.356 0.644 0.000
E15 Nondiabetic hypoglycaemic coma
0.350 0.649 0.000
L05 Pilonidal cyst
0.346 0.654 0.000
E26.9 Hyperaldosteronism, unspecified
0.340 0.660 0.000
E26.8 Other hyperaldosteronism
0.340 0.660 0.000
E26.1 Secondary hyperaldosteronism
0.340 0.660 0.000
L08.0 Pyoderma
0.339 0.661 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.339 0.661 0.000
L03.8 Cellulitis of other sites
0.334 0.666 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.333 0.667 0.000
E28.9 Ovarian dysfunction, unspecified
0.329 0.671 0.000
E28.8 Other ovarian dysfunction
0.329 0.671 0.000
E28.1 Androgen excess
0.329 0.671 0.000
E28.0 Oestrogen excess
0.329 0.671 0.000
E14 Unspecified diabetes mellitus
0.326 0.674 0.000
L01 Impetigo
0.325 0.675 0.000
L00 Staphylococcal scalded skin syndrome
0.325 0.675 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.324 0.676 0.000
E21.4 Other specified disorders of parathyroid gland
0.324 0.676 0.000
L04 Acute lymphadenitis
0.324 0.676 0.000
E51.2 Wernicke's encephalopathy
0.323 0.677 0.000
L08.1 Erythrasma
0.322 0.678 0.000
E13.9 Without complications
0.316 0.684 0.000
E05.5 Thyroid crisis or storm
0.315 0.685 0.000
E05.4 Thyrotoxicosis factitia
0.315 0.685 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.315 0.685 0.000
E03.9 Hypothyroidism, unspecified
0.304 0.696 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.298 0.702 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.298 0.702 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.298 0.702 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.298 0.702 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.298 0.702 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.298 0.702 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.298 0.702 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.298 0.702 0.000
E03.5 Myxoedema coma
0.297 0.703 0.000
E03.4 Atrophy of thyroid (acquired)
0.297 0.703 0.000
E03.3 Postinfectious hypothyroidism
0.297 0.703 0.000
E03.1 Congenital hypothyroidism without goitre
0.297 0.703 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.297 0.703 0.000
E61.2 Magnesium deficiency
0.289 0.710 0.000
E06 Thyroiditis
0.288 0.711 0.000
E46 Unspecified protein-energy malnutrition
0.288 0.712 0.000
L05.0 Pilonidal cyst with abscess
0.286 0.714 0.000
E28.3 Primary ovarian failure
0.285 0.715 0.000
E34.5 Androgen resistance syndrome
0.285 0.715 0.000
E34.4 Constitutional tall stature
0.285 0.715 0.000
E34.3 Short stature, not elsewhere classified
0.285 0.715 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.285 0.715 0.000
E34.1 Other hypersecretion of intestinal hormones
0.285 0.715 0.000
E44.1 Mild protein-energy malnutrition
0.284 0.715 0.000
E44.0 Moderate protein-energy malnutrition
0.284 0.715 0.000
E51.9 Thiamine deficiency, unspecified
0.284 0.716 0.000
E51.8 Other manifestations of thiamine deficiency
0.284 0.716 0.000
E51.1 Beriberi
0.284 0.716 0.000
E61.1 Iron deficiency
0.280 0.720 0.000
E23.2 Diabetes insipidus
0.278 0.722 0.000
E21.3 Hyperparathyroidism, unspecified
0.274 0.726 0.000
E61.9 Deficiency of nutrient element, unspecified
0.273 0.727 0.000
E61.8 Deficiency of other specified nutrient elements
0.273 0.727 0.000
E61.7 Deficiency of multiple nutrient elements
0.273 0.727 0.000
E61.6 Vanadium deficiency
0.273 0.727 0.000
E61.5 Molybdenum deficiency
0.273 0.727 0.000
E61.4 Chromium deficiency
0.273 0.727 0.000
E61.3 Manganese deficiency
0.273 0.727 0.000
E61.0 Copper deficiency
0.273 0.727 0.000
E24.9 Cushing's syndrome, unspecified
0.272 0.727 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.271 0.729 0.000
E23.1 Drug-induced hypopituitarism
0.271 0.729 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.266 0.734 0.000
L03.9 Cellulitis, unspecified
0.266 0.734 0.000
E21.0 Primary hyperparathyroidism
0.260 0.740 0.000
E23.6 Other disorders of pituitary gland
0.258 0.741 0.000
E10.3 With ophthalmic complications
0.257 0.743 0.000
E50.9 Vitamin A deficiency, unspecified
0.256 0.744 0.000
E50.8 Other manifestations of vitamin A deficiency
0.256 0.744 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.256 0.744 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.256 0.744 0.000
E50.5 Vitamin A deficiency with night blindness
0.256 0.744 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.256 0.744 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.256 0.744 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.256 0.744 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.256 0.744 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.256 0.744 0.000
E56.9 Vitamin deficiency, unspecified
0.256 0.744 0.000
E56.8 Deficiency of other vitamins
0.256 0.744 0.000
E56.1 Deficiency of vitamin K
0.256 0.744 0.000
E56.0 Deficiency of vitamin E
0.256 0.744 0.000
E63.9 Nutritional deficiency, unspecified
0.256 0.744 0.000
E63.8 Other specified nutritional deficiencies
0.256 0.744 0.000
E63.1 Imbalance of constituents of food intake
0.256 0.744 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.256 0.744 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.256 0.744 0.000
E64.8 Sequelae of other nutritional deficiencies
0.256 0.744 0.000
E64.3 Sequelae of rickets
0.256 0.744 0.000
E64.2 Sequelae of vitamin C deficiency
0.256 0.744 0.000
E64.1 Sequelae of vitamin A deficiency
0.256 0.744 0.000
E64.0 Sequelae of protein-energy malnutrition
0.256 0.744 0.000
L04.2 Acute lymphadenitis of upper limb
0.249 0.751 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.248 0.752 0.000
E34.9 Endocrine disorder, unspecified
0.248 0.752 0.000
E05.8 Other thyrotoxicosis
0.247 0.753 0.000
E28.2 Polycystic ovarian syndrome
0.244 0.756 0.000
E14.3 With ophthalmic complications
0.242 0.758 0.000
E34.0 Carcinoid syndrome
0.238 0.762 0.001
E14.6 With other specified complications
0.238 0.762 0.000
L04.0 Acute lymphadenitis of face, head and neck
0.238 0.762 0.000
L03.0 Cellulitis of finger and toe
0.236 0.764 0.000
E14.7 With multiple complications
0.234 0.766 0.000
E14.2 Withrenal complications
0.234 0.766 0.000
E14.0 With coma
0.234 0.766 0.000
L01.1 Impetiginisation of other dermatoses
0.233 0.766 0.000
L01.0 Impetigo [any organism] [any site]
0.233 0.766 0.000
E55 Vitamin D deficiency
0.233 0.767 0.001
E03.8 Other specified hypothyroidism
0.232 0.768 0.000
L04.8 Acute lymphadenitis of other sites
0.232 0.768 0.000
L04.3 Acute lymphadenitis of lower limb
0.232 0.768 0.000
L04.1 Acute lymphadenitis of trunk
0.232 0.768 0.000
E23.7 Disorder of pituitary gland, unspecified
0.230 0.769 0.000
E14.8 With unspecified complications
0.225 0.775 0.000
E53 Deficiency of other B group vitamins
0.224 0.775 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.223 0.776 0.000
E14.5 With peripheral circulatory complications
0.223 0.777 0.000
E34.8 Other specified endocrine disorders
0.221 0.779 0.001
L05.9 Pilonidal cyst without abscess
0.220 0.780 0.000
E14.4 With neurological complications
0.217 0.783 0.000
L03.1 Cellulitis of other parts of limb
0.211 0.789 0.000
E14.1 With ketoacidosis
0.210 0.790 0.000
E06.5 Other chronic thyroiditis
0.207 0.793 0.000
E06.4 Drug-induced thyroiditis
0.207 0.793 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.207 0.793 0.000
E06.1 Subacute thyroiditis
0.207 0.793 0.000
E06.0 Acute thyroiditis
0.207 0.793 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.205 0.795 0.000
L04.9 Acute lymphadenitis, unspecified
0.202 0.797 0.000
E26.0 Primary hyperaldosteronism
0.197 0.802 0.001
E06.9 Thyroiditis, unspecified
0.188 0.812 0.000
E16 Other disorders of pancreatic internal secretion
0.177 0.823 0.000
E55.0 Rickets, active
0.167 0.833 0.001
E53.1 Pyridoxine deficiency
0.161 0.839 0.000
E53.0 Riboflavin deficiency
0.161 0.839 0.000
E53.9 Vitamin B deficiency, unspecified
0.160 0.839 0.000
E23.0 Hypopituitarism
0.138 0.862 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.127 0.873 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.127 0.873 0.000
E16.4 Abnormal secretion of gastrin
0.127 0.873 0.000
E16.3 Increased secretion of glucagon
0.127 0.873 0.000
E06.3 Autoimmune thyroiditis
0.118 0.881 0.000
E16.1 Other hypoglycaemia
0.098 0.902 0.001
E16.2 Hypoglycaemia, unspecified
0.097 0.903 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.089 0.910 0.001
E04 Other non-toxic goitre
0.087 0.913 0.000
E04.8 Other specified non-toxic goitre
0.062 0.938 0.000
E14.9 Without complications
0.062 0.938 0.000
E04.0 Non-toxic diffuse goitre
0.058 0.942 0.000
E55.9 Vitamin D deficiency, unspecified
0.042 0.957 0.001
E04.1 Non-toxic single thyroid nodule
0.043 0.957 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.040 0.960 0.000
J44 Other chronic obstructive pulmonary disease
0.033 0.967 0.000
E04.9 Non-toxic goitre, unspecified
0.032 0.968 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.031 0.969 0.000
E53.8 Deficiency of other specified B group vitamins
0.030 0.970 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.029 0.971 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.027 0.973 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.025 0.975 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.025 0.975 0.000
L10-L14 Bullous disorders
0.024 0.976 0.000
G61.0 Guillain-Barre syndrome
0.023 0.977 0.000
G61 Inflammatory polyneuropathy
0.023 0.977 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.023 0.977 0.000
G62 Other polyneuropathies
0.022 0.978 0.000
G60 Hereditary and idiopathic neuropathy
0.022 0.978 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.021 0.979 0.000
G60.0 Hereditary motor and sensory neuropathy
0.021 0.979 0.000
L50-L54 Urticaria and erythema
0.021 0.979 0.000
G62.9 Polyneuropathy, unspecified
0.020 0.980 0.000
L12 Pemphigoid
0.020 0.980 0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.019 0.981 0.000
G62.8 Other specified polyneuropathies
0.019 0.981 0.000
G61.8 Other inflammatory polyneuropathies
0.019 0.981 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.019 0.981 0.000
L56 Other acute skin changes due to ultraviolet radiation
0.019 0.981 0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified
0.019 0.981 0.000
E70-E90 Metabolic disorders
0.019 0.981 0.000
L20-L30 Dermatitis and eczema
0.018 0.982 0.000
L10 Pemphigus
0.018 0.982 0.000
L53 Other erythematous conditions
0.018 0.982 0.000
L53.8 Other specified erythematous conditions
0.018 0.982 0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.018 0.982 0.000
L58 Radiodermatitis
0.018 0.982 0.000
L55 Sunburn
0.018 0.982 0.000
L14 Bullous disorders in diseases classified elsewhere
0.017 0.983 0.000
L11 Other acantholytic disorders
0.017 0.983 0.000
G61.1 Serum neuropathy
0.017 0.983 0.000
G64 Other disorders of peripheral nervous system
0.016 0.983 0.000
G63.2 Diabetic polyneuropathy
0.016 0.984 0.000
L13 Other bullous disorders
0.016 0.984 0.000
G60.3 Idiopathic progressive neuropathy
0.016 0.984 0.000
G60.2 Neuropathy in association with hereditary ataxia
0.016 0.984 0.000
G60.1 Refsum's disease
0.016 0.984 0.000
G62.2 Polyneuropathy due to other toxic agents
0.016 0.984 0.000
L57.4 Cutis laxa senilis
0.016 0.984 0.000
L21 Seborrhoeic dermatitis
0.016 0.984 0.000
G62.0 Drug-induced polyneuropathy
0.016 0.984 0.000
L52 Erythema nodosum
0.016 0.984 0.000
L12.9 Pemphigoid, unspecified
0.016 0.984 0.000
L30 Other dermatitis
0.016 0.984 0.000
L12.0 Bullous pemphigoid
0.015 0.985 0.000
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.015 0.985 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.015 0.985 0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.015 0.985 0.000
L57.5 Actinic granuloma
0.015 0.985 0.000
L57.3 Poikiloderma of Civatte
0.015 0.985 0.000
L57.2 Cutis rhomboidalis nuchae
0.015 0.985 0.000
L57.1 Actinic reticuloid
0.015 0.985 0.000
L54 Erythema in diseases classified elsewhere
0.015 0.985 0.000
E74 Other disorders of carbohydrate metabolism
0.015 0.985 0.000
G62.1 Alcoholic polyneuropathy
0.015 0.985 0.000
L12.1 Cicatricial pemphigoid
0.014 0.985 0.000
G60.8 Other hereditary and idiopathic neuropathies
0.014 0.985 0.000
L25 Unspecified contact dermatitis
0.014 0.985 0.000
G61.9 Inflammatory polyneuropathy, unspecified
0.014 0.986 0.000
L10.9 Pemphigus, unspecified
0.014 0.986 0.000
L30.9 Dermatitis, unspecified
0.014 0.986 0.000
L12.8 Other pemphigoid
0.014 0.986 0.000
L12.3 Acquired epidermolysis bullosa
0.014 0.986 0.000
L12.2 Chronic bullous disease of childhood
0.014 0.986 0.000
L21.9 Seborrhoeic dermatitis, unspecified
0.014 0.986 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.014 0.986 0.000
G63.8 Polyneuropathy in other diseases classified elsewhere
0.014 0.986 0.000
G63.6 Polyneuropathy in other musculoskeletal disorders
0.014 0.986 0.000
G63.5 Polyneuropathy in systemic connective tissue disorders
0.014 0.986 0.000
G63.4 Polyneuropathy in nutritional deficiency
0.014 0.986 0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.014 0.986 0.000
G63.1 Polyneuropathy in neoplastic disease
0.014 0.986 0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.014 0.986 0.000
L20 Atopic dermatitis
0.014 0.986 0.000
L56.4 Polymorphous light eruption
0.013 0.986 0.000
L56.3 Solar urticaria
0.013 0.986 0.000
L56.2 Photocontact dermatitis [berloque dermatitis]
0.013 0.986 0.000
L56.1 Drug photoallergic response
0.013 0.986 0.000
L56.0 Drug phototoxic response
0.013 0.986 0.000
E84 Cystic fibrosis
0.013 0.986 0.000
E79 Disorders of purine and pyrimidine metabolism
0.013 0.986 0.000
E77 Disorders of glycoprotein metabolism
0.013 0.986 0.000
E76 Disorders of glycosaminoglycan metabolism
0.013 0.986 0.000
E72 Other disorders of amino-acid metabolism
0.013 0.986 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.013 0.986 0.000
E70 Disorders of aromatic amino-acid metabolism
0.013 0.986 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.013 0.986 0.000
L24 Irritant contact dermatitis
0.013 0.987 0.000
L26 Exfoliative dermatitis
0.013 0.987 0.000
L22 Diaper [napkin] dermatitis
0.013 0.987 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.013 0.987 0.000
L10.8 Other pemphigus
0.013 0.987 0.000
L10.5 Drug-induced pemphigus
0.013 0.987 0.000
L10.4 Pemphigus erythematosus
0.013 0.987 0.000
L10.3 Brazilian pemphigus [fogo selvagem]
0.013 0.987 0.000
L10.2 Pemphigus foliaceus
0.013 0.987 0.000
L10.1 Pemphigus vegetans
0.013 0.987 0.000
L10.0 Pemphigus vulgaris
0.013 0.987 0.000
L53.3 Other chronic figurate erythema
0.013 0.987 0.000
L53.2 Erythema marginatum
0.013 0.987 0.000
L53.1 Erythema annulare centrifugum
0.013 0.987 0.000
L53.0 Toxic erythema
0.013 0.987 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.013 0.987 0.000
L55.9 Sunburn, unspecified
0.013 0.987 0.000
L55.8 Other sunburn
0.013 0.987 0.000
L55.2 Sunburn of third degree
0.013 0.987 0.000
L55.1 Sunburn of second degree
0.013 0.987 0.000
L55.0 Sunburn of first degree
0.013 0.987 0.000
L58.9 Radiodermatitis, unspecified
0.013 0.987 0.000
L58.1 Chronic radiodermatitis
0.013 0.987 0.000
L58.0 Acute radiodermatitis
0.013 0.987 0.000
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified
0.013 0.987 0.000
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation
0.013 0.987 0.000
L59.0 Erythema ab igne [dermatitis ab igne]
0.013 0.987 0.000
E73 Lactose intolerance
0.013 0.987 0.000
E75.5 Other lipid storage disorders
0.013 0.987 0.000
L60-L75 Disorders of skin appendages
0.013 0.987 0.000
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.013 0.987 0.000
L30.4 Erythema intertrigo
0.012 0.987 0.000
L11.9 Acantholytic disorder, unspecified
0.012 0.987 0.000
L11.8 Other specified acantholytic disorders
0.012 0.987 0.000
L11.1 Transient acantholytic dermatosis [Grover]
0.012 0.987 0.000
L51 Erythema multiforme
0.012 0.988 0.000
L11.0 Acquired keratosis follicularis
0.012 0.988 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.012 0.988 0.000
L30.1 Dyshidrosis [pompholyx]
0.012 0.988 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.012 0.988 0.000
L28 Lichen simplex chronicus and prurigo
0.012 0.988 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.012 0.988 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.012 0.988 0.000
L25.9 Unspecified contact dermatitis, unspecified cause
0.012 0.988 0.000
L13.9 Bullous disorder, unspecified
0.012 0.988 0.000
L13.8 Other specified bullous disorders
0.012 0.988 0.000
L13.1 Subcorneal pustular dermatitis
0.012 0.988 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.012 0.988 0.000
E83 Disorders of mineral metabolism
0.012 0.988 0.000
L21.8 Other seborrhoeic dermatitis
0.011 0.988 0.000
L21.1 Seborrhoeic infantile dermatitis
0.011 0.988 0.000
L21.0 Seborrhoea capitis
0.011 0.988 0.000
E04.2 Non-toxic multinodular goitre
0.011 0.989 0.000
L30.5 Pityriasis alba
0.011 0.989 0.000
L30.3 Infective dermatitis
0.011 0.989 0.000
L30.2 Cutaneous autosensitisation
0.011 0.989 0.000
L30.0 Nummular dermatitis
0.011 0.989 0.000
E80.2 Other porphyria
0.011 0.989 0.000
T42.1 Iminostilbenes
0.011 0.989 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.011 0.989 0.000
T39.0 Salicylates
0.011 0.989 0.000
E75.6 Lipid storage disorder, unspecified
0.011 0.989 0.000
E75.4 Neuronal ceroid lipofuscinosis
0.011 0.989 0.000
E75.3 Sphingolipidosis, unspecified
0.011 0.989 0.000
E75.2 Other sphingolipidosis
0.011 0.989 0.000
E75.1 Other gangliosidosis
0.011 0.989 0.000
E75.0 GM2 gangliosidosis
0.011 0.989 0.000
E88 Other metabolic disorders
0.011 0.989 0.000
L54.8 Erythema in other diseases classified elsewhere
0.011 0.989 0.000
L54.0 Erythema marginatum in acute rheumatic fever
0.011 0.989 0.000
E80.6 Other disorders of bilirubin metabolism
0.011 0.989 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.011 0.989 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.011 0.989 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.011 0.989 0.000
E74.8 Other specified disorders of carbohydrate metabolism
0.011 0.989 0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.011 0.989 0.000
E74.2 Disorders of galactose metabolism
0.011 0.989 0.000
E74.1 Disorders of fructose metabolism
0.011 0.989 0.000
E74.0 Glycogen storage disease
0.011 0.989 0.000
L27 Dermatitis due to substances taken internally
0.011 0.989 0.000
L50 Urticaria
0.011 0.989 0.000
L23 Allergic contact dermatitis
0.011 0.989 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.011 0.989 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.011 0.989 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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