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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs520161
log Bayes Factor = 5.3246
Chromosome 7   position 28,210,660  (GRCh37) Explore rs520161 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M50-M54 Other dorsopathies
0.998 0.002 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.997 0.003 0.000
E11.9 Without complications
0.997 0.003 0.000
M51 Other intervertebral disk disorders
0.997 0.003 0.000
M45-M49 Spondylopathies
0.996 0.004 0.000
M20-M25 Other joint disorders
0.993 0.007 0.000
M48 Other spondylopathies
0.992 0.008 0.000
M48.0 Spinal stenosis
0.990 0.010 0.000
M48.06 Spinal stenosis (Lumbar region)
0.990 0.010 0.000
M35 Other systemic involvement of connective tissue
0.989 0.011 0.000
M51.2 Other specified intervertebral disk displacement
0.985 0.015 0.000
M35.0 Sicca syndrome [Sjogren]
0.985 0.015 0.000
M47 Spondylosis
0.979 0.021 0.000
M05-M14 Inflammatory polyarthropathies
0.973 0.027 0.000
M47.9 Spondylosis, unspecified
0.971 0.029 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.965 0.035 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.964 0.036 0.000
M06 Other rheumatoid arthritis
0.955 0.045 0.000
M50 Cervical disk disorders
0.950 0.050 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.937 0.063 0.000
M50.0 Cervical disk disorder with myelopathy
0.934 0.066 0.000
M06.9 Rheumatoid arthritis, unspecified
0.932 0.068 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.919 0.081 0.000
M34 Systemic sclerosis
0.909 0.091 0.000
M86-M90 Other osteopathies
0.909 0.091 0.000
M25 Other joint disorders, not elsewhere classified
0.908 0.092 0.000
E11 Non-insulin-dependent diabetes mellitus
0.898 0.102 0.000
M05 Seropositive rheumatoid arthritis
0.892 0.108 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.884 0.116 0.000
M51.9 Intervertebral disk disorder, unspecified
0.874 0.126 0.000
E10-E14 Diabetes mellitus
0.861 0.139 0.000
E10 Insulin-dependent diabetes mellitus
0.850 0.150 0.000
M25.8 Other specified joint disorders
0.850 0.150 0.000
M25.4 Effusion of joint
0.836 0.164 0.000
M35.7 Hypermobility syndrome
0.833 0.167 0.000
M35.2 Behcet's disease
0.828 0.172 0.000
M14 Arthropathies in other diseases classified elsewhere
0.827 0.173 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.824 0.176 0.000
M48.09 Spinal stenosis (Site unspecified)
0.816 0.184 0.000
M25.46 Effusion of joint (Lower leg)
0.809 0.191 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.807 0.193 0.000
M06.3 Rheumatoid nodule
0.801 0.199 0.000
E11.3 With ophthalmic complications
0.797 0.203 0.000
M31 Other necrotising vasculopathies
0.796 0.204 0.000
E10.5 With peripheral circulatory complications
0.796 0.204 0.000
M89 Other disorders of bone
0.792 0.208 0.000
M34.9 Systemic sclerosis, unspecified
0.782 0.218 0.000
M86 Osteomyelitis
0.782 0.218 0.000
M47.2 Other spondylosis with radiculopathy
0.781 0.219 0.000
M90 Osteopathies in diseases classified elsewhere
0.779 0.221 0.000
M50.8 Other cervical disk disorders
0.776 0.224 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.772 0.228 0.000
M35.1 Other overlap syndromes
0.766 0.233 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.766 0.234 0.000
M60-M63 Disorders of muscles
0.765 0.235 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.765 0.235 0.000
M20 Acquired deformities of fingers and toes
0.764 0.236 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.763 0.237 0.000
M21 Other acquired deformities of limbs
0.762 0.238 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.755 0.245 0.000
M08 Juvenile arthritis
0.748 0.252 0.000
M51.3 Other specified intervertebral disk degeneration
0.745 0.254 0.000
M48.04 Spinal stenosis (Thoracic region)
0.744 0.256 0.000
M06.4 Inflammatory polyarthropathy
0.743 0.257 0.000
M51.4 Schmorl's nodes
0.743 0.257 0.000
E10.9 Without complications
0.741 0.259 0.000
M48.8 Other specified spondylopathies
0.740 0.260 0.000
M34.1 CR(E)ST syndrome
0.738 0.262 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.736 0.264 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.728 0.272 0.000
M34.8 Other forms of systemic sclerosis
0.728 0.272 0.000
E10.8 With unspecified complications
0.726 0.274 0.000
M25.9 Joint disorder, unspecified
0.725 0.275 0.000
M89.9 Disorder of bone, unspecified
0.725 0.275 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.725 0.275 0.000
M48.9 Spondylopathy, unspecified
0.724 0.276 0.000
E11.8 With unspecified complications
0.724 0.276 0.000
M14.6 Neuropathic arthropathy
0.722 0.278 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.722 0.278 0.000
M50.2 Other cervical disk displacement
0.721 0.279 0.000
M89.0 Algoneurodystrophy
0.715 0.285 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.715 0.285 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.713 0.287 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.713 0.287 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.712 0.288 0.000
M48.4 Fatigue fracture of vertebra
0.711 0.289 0.000
M48.3 Traumatic spondylopathy
0.711 0.289 0.000
M48.2 Kissing spine
0.711 0.289 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.711 0.289 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.710 0.290 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.710 0.290 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.710 0.290 0.000
M25.0 Haemarthrosis
0.710 0.290 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.709 0.291 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.709 0.291 0.000
M35.5 Multifocal fibrosclerosis
0.709 0.291 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.709 0.291 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.705 0.295 0.000
M21.3 Wrist or foot drop (acquired)
0.705 0.295 0.000
M32 Systemic lupus erythematosus
0.703 0.297 0.000
E10.2 With renal complications
0.702 0.298 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.702 0.298 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.701 0.299 0.000
M25.83 Other specified joint disorders (Forearm)
0.700 0.300 0.000
E11.4 With neurological complications
0.699 0.301 0.000
E14 Unspecified diabetes mellitus
0.699 0.301 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.698 0.302 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.696 0.304 0.000
E10.4 With neurological complications
0.693 0.307 0.000
M53 Other dorsopathies, not elsewhere classified
0.692 0.308 0.000
M47.1 Other spondylosis with myelopathy
0.691 0.309 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.689 0.311 0.000
M35.8 Other specified systemic involvement of connective tissue
0.688 0.312 0.000
M06.8 Other specified rheumatoid arthritis
0.685 0.315 0.000
M06.2 Rheumatoid bursitis
0.685 0.315 0.000
M06.1 Adult-onset Still's disease
0.685 0.315 0.000
M25.42 Effusion of joint (Upper arm)
0.684 0.316 0.000
M05.1 Rheumatoid lung disease
0.683 0.317 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.677 0.322 0.000
M90.7 Fracture of bone in neoplastic disease
0.677 0.323 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.675 0.325 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.672 0.328 0.000
M33 Dermatopolymyositis
0.672 0.328 0.000
M25.41 Effusion of joint (Shoulder region)
0.671 0.329 0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)
0.671 0.329 0.000
M25.88 Other specified joint disorders (Other)
0.667 0.332 0.000
E10.6 With other specified complications
0.664 0.336 0.000
M31.9 Necrotising vasculopathy, unspecified
0.664 0.336 0.000
M51.8 Other specified intervertebral disk disorders
0.661 0.339 0.000
M20.4 Other hammer toe(s) (acquired)
0.660 0.340 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.659 0.341 0.000
E10.3 With ophthalmic complications
0.659 0.341 0.000
M25.43 Effusion of joint (Forearm)
0.657 0.343 0.000
E11.6 With other specified complications
0.656 0.344 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.656 0.344 0.000
M31.8 Other specified necrotising vasculopathies
0.655 0.345 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.654 0.346 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.652 0.348 0.000
M34.0 Progressive systemic sclerosis
0.652 0.348 0.000
M25.2 Flail joint
0.651 0.349 0.000
M25.1 Fistula of joint
0.651 0.349 0.000
M11 Other crystal arthropathies
0.651 0.349 0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)
0.649 0.351 0.000
M25.84 Other specified joint disorders (Hand)
0.646 0.354 0.000
E11.7 With multiple complications
0.644 0.356 0.000
M49 Spondylopathies in diseases classified elsewhere
0.642 0.358 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.641 0.359 0.000
M05.8 Other seropositive rheumatoid arthritis
0.640 0.360 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.640 0.360 0.000
M05.0 Felty's syndrome
0.640 0.360 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.639 0.361 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.637 0.363 0.000
M86.6 Other chronic osteomyelitis
0.637 0.363 0.000
M00-M03 Infectious arthropathies
0.637 0.363 0.000
M05.2 Rheumatoid vasculitis
0.634 0.366 0.000
M31.0 Hypersensitivity angiitis
0.632 0.368 0.000
M86.1 Other acute osteomyelitis
0.631 0.368 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.630 0.370 0.000
M89.04 Algoneurodystrophy (Hand)
0.624 0.376 0.000
M21.7 Unequal limb length (acquired)
0.624 0.376 0.000
M89.91 Disorder of bone, unspecified (Shoulder region)
0.623 0.377 0.000
M06.0 Seronegative rheumatoid arthritis
0.622 0.378 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.621 0.379 0.000
M20.2 Hallux rigidus
0.620 0.380 0.000
M12 Other specific arthropathies
0.620 0.380 0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)
0.619 0.381 0.000
E13 Other specified diabetes mellitus
0.618 0.382 0.000
E12 Malnutrition-related diabetes mellitus
0.618 0.382 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.616 0.384 0.000
M31.7 Microscopic polyangiitis
0.615 0.385 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.613 0.387 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.613 0.387 0.000
M90.6 Osteitis deformans in neoplastic disease
0.613 0.387 0.000
M24 Other specific joint derangements
0.613 0.387 0.000
M25.86 Other specified joint disorders (Lower leg)
0.613 0.387 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.612 0.388 0.000
M54 Dorsalgia
0.611 0.389 0.000
E10.7 With multiple complications
0.610 0.390 0.000
M25.89 Other specified joint disorders (Site unspecified)
0.609 0.391 0.000
M25.82 Other specified joint disorders (Upper arm)
0.609 0.391 0.000
M25.80 Other specified joint disorders (Multiple sites)
0.609 0.391 0.000
M50.1 Cervical disk disorder with radiculopathy
0.608 0.392 0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)
0.606 0.394 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.602 0.398 0.000
M25.49 Effusion of joint (Site unspecified)
0.600 0.400 0.000
M25.48 Effusion of joint (Other)
0.600 0.400 0.000
M25.40 Effusion of joint (Multiple sites)
0.597 0.403 0.000
M80-M85 Disorders of bone density and structure
0.597 0.403 0.000
E11.5 With peripheral circulatory complications
0.596 0.404 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.593 0.407 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.593 0.407 0.000
M14.4 Arthropathy in amyloidosis
0.593 0.407 0.000
M14.3 Lipoid dermatoarthritis
0.593 0.407 0.000
M14.2 Diabetic arthropathy
0.593 0.407 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.593 0.407 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.593 0.407 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.593 0.407 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.590 0.409 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.590 0.409 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.590 0.409 0.000
M89.03 Algoneurodystrophy (Forearm)
0.589 0.411 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.588 0.412 0.000
M08.2 Juvenile arthritis with systemic onset
0.587 0.413 0.000
M62 Other disorders of muscle
0.587 0.413 0.000
M40-M43 Deforming dorsopathies
0.585 0.415 0.000
E14.1 With ketoacidosis
0.585 0.415 0.000
M21.9 Acquired deformity of limb, unspecified
0.583 0.417 0.000
M48.86 Other specified spondylopathies (Lumbar region)
0.581 0.419 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.580 0.420 0.000
M89.07 Algoneurodystrophy (Ankle and foot)
0.579 0.421 0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)
0.579 0.421 0.000
M20.5 Other deformities of toe(s) (acquired)
0.578 0.422 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.574 0.425 0.000
M06.38 Rheumatoid nodule (Other)
0.574 0.425 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.574 0.425 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.574 0.425 0.000
M06.33 Rheumatoid nodule (Forearm)
0.574 0.425 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.574 0.425 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.574 0.425 0.000
M86.8 Other osteomyelitis
0.573 0.426 0.000
M90.78 Fracture of bone in neoplastic disease (Other)
0.572 0.428 0.000
M31.2 Lethal midline granuloma
0.571 0.429 0.000
M89.6 Osteopathy after poliomyelitis
0.568 0.432 0.000
M89.2 Other disorders of bone development and growth
0.568 0.432 0.000
M89.1 Epiphyseal arrest
0.568 0.432 0.000
M25.06 Haemarthrosis (Lower leg)
0.567 0.433 0.000
E14.0 With coma
0.567 0.433 0.000
M51.37 Other intervertebral disc degeneration, lumbosacral region
0.565 0.435 0.000
M86.9 Osteomyelitis, unspecified
0.563 0.437 0.000
M89.98 Disorder of bone, unspecified (Other)
0.563 0.437 0.000
M60 Myositis
0.563 0.437 0.000
M06.34 Rheumatoid nodule (Hand)
0.563 0.437 0.000
M87 Osteonecrosis
0.561 0.439 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.560 0.439 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.560 0.439 0.000
M86.3 Chronic multifocal osteomyelitis
0.560 0.439 0.000
M86.2 Subacute osteomyelitis
0.560 0.439 0.000
M86.0 Acute haematogenous osteomyelitis
0.560 0.439 0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)
0.560 0.440 0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)
0.560 0.440 0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)
0.560 0.440 0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)
0.560 0.440 0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)
0.560 0.440 0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)
0.560 0.440 0.000
M21.4 Flat foot [pes planus] (acquired)
0.559 0.441 0.000
M90.8 Osteopathy in other diseases classified elsewhere
0.559 0.441 0.000
M90.5 Osteonecrosis in other diseases classified elsewhere
0.559 0.441 0.000
M90.4 Osteonecrosis due to heamoglobinopathy
0.559 0.441 0.000
M90.3 Osteonecrosis in caisson disease
0.559 0.441 0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere
0.559 0.441 0.000
M90.0 Tuberculosis of bone
0.559 0.441 0.000
M84 Disorders of continuity of bone
0.555 0.445 0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.552 0.448 0.000
M30 Polyarteritis nodosa and related conditions
0.551 0.449 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.551 0.449 0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)
0.551 0.449 0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)
0.550 0.449 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.549 0.451 0.000
M61 Calcification and ossification of muscle
0.549 0.451 0.000
M21.8 Other specified acquired deformities of limbs
0.547 0.453 0.000
M89.92 Disorder of bone, unspecified (Upper arm)
0.544 0.456 0.000
M50.9 Cervical disk disorder, unspecified
0.543 0.457 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.540 0.460 0.000
E14.6 With other specified complications
0.538 0.462 0.000
M25.94 Joint disorder, unspecified (Hand)
0.538 0.462 0.000
E14.2 Withrenal complications
0.537 0.463 0.000
M08.9 Juvenile arthritis, unspecified
0.536 0.463 0.000
M08.8 Other juvenile arthritis
0.536 0.463 0.000
M08.4 Pauciarticular juvenile arthritis
0.536 0.463 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.536 0.463 0.000
M08.1 Juvenile ankylosing spondylitis
0.536 0.463 0.000
M08.0 Juvenile rheumatoid arthritis
0.536 0.463 0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)
0.535 0.465 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.533 0.467 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.533 0.467 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.533 0.467 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.533 0.467 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.533 0.467 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.533 0.467 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.533 0.467 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.533 0.467 0.000
M05.19 Rheumatoid lung disease (Site unspecified)
0.533 0.467 0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)
0.533 0.467 0.000
M10 Gout
0.533 0.467 0.000
M53.8 Other specified dorsopathies
0.532 0.467 0.000
M48.92 Spondylopathy, unspecified (Cervical region)
0.532 0.468 0.000
M48.89 Other specified spondylopathies (Site unspecified)
0.530 0.469 0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)
0.530 0.469 0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)
0.530 0.469 0.000
M48.84 Other specified spondylopathies (Thoracic region)
0.530 0.469 0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)
0.530 0.469 0.000
M48.82 Other specified spondylopathies (Cervical region)
0.530 0.469 0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)
0.530 0.469 0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)
0.530 0.469 0.000
M21.33 Wrist or foot drop (acquired) (Forearm)
0.530 0.469 0.000
M25.93 Joint disorder, unspecified (Forearm)
0.528 0.471 0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.528 0.472 0.000
M36.3 Arthropathy in other blood disorders
0.528 0.472 0.000
M36.2 Haemophilic arthropathy
0.528 0.472 0.000
M36.1 Arthropathy in neoplastic disease
0.528 0.472 0.000
M36.0 Dermato(poly)myositis in neoplastic disease
0.528 0.472 0.000
M47.12 Other spondylosis with myelopathy (Cervical region)
0.526 0.474 0.000
M25.3 Other instability of joint
0.526 0.474 0.000
M89.96 Disorder of bone, unspecified (Lower leg)
0.525 0.475 0.000
M13 Other arthritis
0.525 0.475 0.000
M86.17 Other acute osteomyelitis (Ankle and foot)
0.524 0.476 0.000
M99 Biomechanical lesions, not elsewhere classified
0.523 0.477 0.000
E10.0 With coma
0.523 0.477 0.000
M54.5 Low back pain
0.522 0.478 0.000
E14.8 With unspecified complications
0.521 0.478 0.000
M25.99 Joint disorder, unspecified (Site unspecified)
0.520 0.480 0.000
M25.98 Joint disorder, unspecified (Other)
0.520 0.480 0.000
M25.92 Joint disorder, unspecified (Upper arm)
0.520 0.480 0.000
M25.90 Joint disorder, unspecified (Multiple sites)
0.520 0.480 0.000
M89.99 Disorder of bone, unspecified (Site unspecified)
0.520 0.480 0.000
M89.93 Disorder of bone, unspecified (Forearm)
0.520 0.480 0.000
M89.90 Disorder of bone, unspecified (Multiple sites)
0.520 0.480 0.000
M84.4 Pathological fracture, not elsewhere classified
0.520 0.480 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.519 0.481 0.000
M48.99 Spondylopathy, unspecified (Site unspecified)
0.519 0.481 0.000
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.519 0.481 0.000
M48.97 Spondylopathy, unspecified (Lumbosacral region)
0.519 0.481 0.000
M48.96 Spondylopathy, unspecified (Lumbar region)
0.519 0.481 0.000
M48.95 Spondylopathy, unspecified (Thoracolumbar region)
0.519 0.481 0.000
M48.94 Spondylopathy, unspecified (Thoracic region)
0.519 0.481 0.000
M48.93 Spondylopathy, unspecified (Cervicothoracic region)
0.519 0.481 0.000
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)
0.519 0.481 0.000
M48.90 Spondylopathy, unspecified (Multiple sites in spine)
0.519 0.481 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.519 0.481 0.000
M25.44 Effusion of joint (Hand)
0.518 0.482 0.000
E14.4 With neurological complications
0.516 0.484 0.000
M91-M94 Chondropathies
0.515 0.485 0.000
M89.5 Osteolysis
0.514 0.486 0.000
M54.59 Low back pain (Site unspecified)
0.514 0.486 0.000
M46 Other inflammatory spondylopathies
0.514 0.486 0.000
M90.1 Periostitis in other infectious diseases classified elsewhere
0.513 0.486 0.000
M89.08 Algoneurodystrophy (Other)
0.513 0.487 0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)
0.513 0.487 0.000
M89.02 Algoneurodystrophy (Upper arm)
0.513 0.487 0.000
M89.01 Algoneurodystrophy (Shoulder region)
0.513 0.487 0.000
M89.00 Algoneurodystrophy (Multiple sites)
0.513 0.487 0.000
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified
0.512 0.487 0.000
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region
0.512 0.487 0.000
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)
0.510 0.490 0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)
0.510 0.490 0.000
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)
0.510 0.490 0.000
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)
0.510 0.490 0.000
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)
0.510 0.490 0.000
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)
0.510 0.490 0.000
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)
0.510 0.490 0.000
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)
0.510 0.490 0.000
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)
0.510 0.490 0.000
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)
0.510 0.490 0.000
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)
0.510 0.490 0.000
M48.29 Kissing spine (Site unspecified)
0.510 0.490 0.000
M48.28 Kissing spine (Sacral and sacrococcygeal region)
0.510 0.490 0.000
M48.27 Kissing spine (Lumbosacral region)
0.510 0.490 0.000
M48.26 Kissing spine (Lumbar region)
0.510 0.490 0.000
M48.25 Kissing spine (Thoracolumbar region)
0.510 0.490 0.000
M48.24 Kissing spine (Thoracic region)
0.510 0.490 0.000
M48.23 Kissing spine (Cervicothoracic region)
0.510 0.490 0.000
M48.22 Kissing spine (Cervical region)
0.510 0.490 0.000
M48.21 Kissing spine (Occipito-atlanto-axial region)
0.510 0.490 0.000
M48.20 Kissing spine (Multiple sites in spine)
0.510 0.490 0.000
M48.39 Traumatic spondylopathy (Site unspecified)
0.510 0.490 0.000
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)
0.510 0.490 0.000
M48.37 Traumatic spondylopathy (Lumbosacral region)
0.510 0.490 0.000
M48.36 Traumatic spondylopathy (Lumbar region)
0.510 0.490 0.000
M48.35 Traumatic spondylopathy (Thoracolumbar region)
0.510 0.490 0.000
M48.34 Traumatic spondylopathy (Thoracic region)
0.510 0.490 0.000
M48.33 Traumatic spondylopathy (Cervicothoracic region)
0.510 0.490 0.000
M48.32 Traumatic spondylopathy (Cervical region)
0.510 0.490 0.000
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)
0.510 0.490 0.000
M48.30 Traumatic spondylopathy (Multiple sites in spine)
0.510 0.490 0.000
M48.49 Fatigue fracture of vertebra (Site unspecified)
0.510 0.490 0.000
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)
0.510 0.490 0.000
M48.47 Fatigue fracture of vertebra (Lumbosacral region)
0.510 0.490 0.000
M48.46 Fatigue fracture of vertebra (Lumbar region)
0.510 0.490 0.000
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)
0.510 0.490 0.000
M48.44 Fatigue fracture of vertebra (Thoracic region)
0.510 0.490 0.000
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)
0.510 0.490 0.000
M48.42 Fatigue fracture of vertebra (Cervical region)
0.510 0.490 0.000
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)
0.510 0.490 0.000
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)
0.510 0.490 0.000
M25.09 Haemarthrosis (Site unspecified)
0.509 0.491 0.000
M25.08 Haemarthrosis (Other)
0.509 0.491 0.000
M25.07 Haemarthrosis (Ankle and foot)
0.509 0.491 0.000
M25.05 Haemarthrosis (Pelvic region and thigh)
0.509 0.491 0.000
M25.04 Haemarthrosis (Hand)
0.509 0.491 0.000
M25.03 Haemarthrosis (Forearm)
0.509 0.491 0.000
M25.02 Haemarthrosis (Upper arm)
0.509 0.491 0.000
M25.01 Haemarthrosis (Shoulder region)
0.509 0.491 0.000
M25.00 Haemarthrosis (Multiple sites)
0.509 0.491 0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.508 0.491 0.000
M86.69 Other chronic osteomyelitis (Site unspecified)
0.507 0.492 0.000
M54.4 Lumbago with sciatica
0.507 0.492 0.000
M54.6 Pain in thoracic spine
0.507 0.493 0.000
M21.39 Wrist or foot drop (acquired)-Site unspec
0.506 0.494 0.000
M21.38 Wrist or foot drop (acquired)-Other
0.506 0.494 0.000
M21.36 Wrist or foot drop (acquired)-Lower leg
0.506 0.494 0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh
0.506 0.494 0.000
M21.34 Wrist or foot drop (acquired) (Hand)
0.506 0.494 0.000
M21.32 Wrist or foot drop (acquired)-Upper arm
0.506 0.494 0.000
M21.31 Wrist or foot drop (acquired)-Shldr region
0.506 0.494 0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)
0.506 0.494 0.000
M90.70 Fracture of bone in neoplastic disease (Multiple sites)
0.505 0.495 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.504 0.496 0.000
M32.8 Other forms of systemic lupus erythematosus
0.504 0.496 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.504 0.496 0.000
M47.09 Anterior spinal and vertebral artery compression syndromes (Site unspecified)
0.503 0.496 0.000
M47.08 Anterior spinal and vertebral artery compression syndromes (Sacral and sacrococcygeal region)
0.503 0.496 0.000
M47.07 Anterior spinal and vertebral artery compression syndromes (Lumbosacral region)
0.503 0.496 0.000
M47.06 Anterior spinal and vertebral artery compression syndromes (Lumbar region)
0.503 0.496 0.000
M47.05 Anterior spinal and vertebral artery compression syndromes (Thoracolumbar region)
0.503 0.496 0.000
M47.04 Anterior spinal and vertebral artery compression syndromes (Thoracic region)
0.503 0.496 0.000
M47.03 Anterior spinal and vertebral artery compression syndromes (Cervicothoracic region)
0.503 0.496 0.000
M47.02 Anterior spinal and vertebral artery compression syndromes (Cervical region)
0.503 0.496 0.000
M47.01 Anterior spinal and vertebral artery compression syndromes (Occipito-atlanto-axial region)
0.503 0.496 0.000
M47.00 Anterior spinal and vertebral artery compression syndromes (Multiple sites in spine)
0.503 0.496 0.000
M48.87 Other specified spondylopathies (Lumbosacral region)
0.502 0.498 0.000
E14.7 With multiple complications
0.501 0.499 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.500 0.499 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.500 0.499 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.500 0.499 0.000
M09.0 Juvenile arthritis in psoriasis
0.500 0.499 0.000
M53.2 Spinal instabilities
0.498 0.502 0.000
M53.9 Dorsopathy, unspecified
0.496 0.504 0.000
M53.1 Cervicobrachial syndrome
0.496 0.504 0.000
M53.0 Cervicocranial syndrome
0.496 0.504 0.000
M21.0 Valgus deformity, not elsewhere classified
0.496 0.504 0.000
M24.7 Protrusio acetabuli
0.496 0.504 0.000
M88 Paget's disease of bone [osteitis deformans]
0.495 0.504 0.001
M47.19 Other spondylosis with myelopathy (Site unspecified)
0.495 0.505 0.000
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)
0.495 0.505 0.000
M47.17 Other spondylosis with myelopathy (Lumbosacral region)
0.495 0.505 0.000
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)
0.495 0.505 0.000
M47.14 Other spondylosis with myelopathy (Thoracic region)
0.495 0.505 0.000
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)
0.495 0.505 0.000
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)
0.495 0.505 0.000
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)
0.495 0.505 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.495 0.505 0.000
M31.1 Thrombotic microangiopathy
0.495 0.505 0.000
M33.2 Polymyositis
0.494 0.505 0.000
M24.5 Contracture of joint
0.493 0.507 0.000
M90.61 Osteitis deformans in neoplastic disease (Shoulder region)
0.493 0.507 0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)
0.493 0.507 0.000
M31.6 Other giant cell arteritis
0.491 0.509 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.491 0.509 0.000
M06.18 Adult-onset Still's disease (Other)
0.491 0.509 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.491 0.509 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.491 0.509 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.491 0.509 0.000
M06.14 Adult-onset Still's disease (Hand)
0.491 0.509 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.491 0.509 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.491 0.509 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.491 0.509 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.491 0.509 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.491 0.509 0.000
M06.28 Rheumatoid bursitis (Other)
0.491 0.509 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.491 0.509 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.491 0.509 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.491 0.509 0.000
M06.24 Rheumatoid bursitis (Hand)
0.491 0.509 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.491 0.509 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.491 0.509 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.491 0.509 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.491 0.509 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.491 0.509 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.491 0.509 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.491 0.509 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.491 0.509 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.491 0.509 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.491 0.509 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.491 0.509 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.491 0.509 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.491 0.509 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.491 0.509 0.000
M05.18 Rheumatoid lung disease (Other)
0.489 0.510 0.000
M05.17 Rheumatoid lung disease (Ankle and foot)
0.489 0.510 0.000
M05.16 Rheumatoid lung disease (Lower leg)
0.489 0.510 0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.489 0.510 0.000
M05.14 Rheumatoid lung disease (Hand)
0.489 0.510 0.000
M05.13 Rheumatoid lung disease (Forearm)
0.489 0.510 0.000
M05.12 Rheumatoid lung disease (Upper arm)
0.489 0.510 0.000
M05.11 Rheumatoid lung disease (Shoulder region)
0.489 0.510 0.000
M05.10 Rheumatoid lung disease (Multiple sites)
0.489 0.510 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.488 0.512 0.000
M90.79 Fracture of bone in neoplastic disease (Site unspecified)
0.486 0.514 0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)
0.486 0.514 0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)
0.486 0.514 0.000
M90.74 Fracture of bone in neoplastic disease (Hand)
0.486 0.514 0.000
M90.73 Fracture of bone in neoplastic disease (Forearm)
0.486 0.514 0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)
0.486 0.514 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.486 0.514 0.000
E13.3 With ophthalmic complications
0.483 0.517 0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)
0.483 0.517 0.000
M33.9 Dermatopolymyositis, unspecified
0.482 0.518 0.000
M33.0 Juvenile dermatomyositis
0.482 0.518 0.000
E11.1 With ketoacidosis
0.481 0.518 0.000
M25.91 Joint disorder, unspecified (Shoulder region)
0.481 0.519 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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