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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs521828
log Bayes Factor = 280.231
Chromosome 6   position 32,291,643  (GRCh37) Explore rs521828 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
H36.0 Diabetic retinopathy
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
H30-H36 Disorders of choroid and retina
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
N00-N08 Glomerular diseases
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
H36 Retinal disorders in diseases classified elsewhere
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
L40-L45 Papulosquamous disorders
1.000 0.000 0.000
N04 Nephrotic syndrome
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
N18 Chronic renal failure
0.999 0.001 0.000
E10.1 With ketoacidosis
0.999 0.001 0.000
L40.9 Psoriasis, unspecified
0.999 0.001 0.000
L40.5 Arthropathic psoriasis
0.999 0.001 0.000
N17-N19 Renal failure
0.999 0.001 0.000
N04.9 Unspecified
0.999 0.001 0.000
M06 Other rheumatoid arthritis
0.000 0.001 0.998
D60-D64 Aplastic and other anaemias
0.998 0.002 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.997 0.003 0.000
E11 Non-insulin-dependent diabetes mellitus
0.997 0.003 0.000
N18.9 Chronic renal failure, unspecified
0.996 0.004 0.000
G56.0 Carpal tunnel syndrome
0.996 0.004 0.000
E27 Other disorders of adrenal gland
0.996 0.004 0.000
D64 Other anaemias
0.995 0.005 0.000
E16 Other disorders of pancreatic internal secretion
0.995 0.005 0.000
M20.1 Hallux valgus (acquired)
0.000 0.005 0.995
E16.2 Hypoglycaemia, unspecified
0.994 0.006 0.000
H34 Retinal vascular occlusions
0.994 0.006 0.000
E27.1 Primary adrenocortical insufficiency
0.993 0.007 0.000
E11.3 With ophthalmic complications
0.993 0.007 0.000
G56 Mononeuropathies of upper limb
0.993 0.007 0.000
D64.9 Anaemia, unspecified
0.992 0.008 0.000
M05-M14 Inflammatory polyarthropathies
0.091 0.011 0.898
G50-G59 Nerve, nerve root and plexus disorders
0.989 0.011 0.000
H34.8 Other retinal vascular occlusions
0.986 0.014 0.000
E14 Unspecified diabetes mellitus
0.986 0.014 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.986 0.014 0.000
N05 Unspecified nephritic syndrome
0.985 0.015 0.000
Chapter VI Diseases of the nervous system
0.985 0.015 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.984 0.016 0.000
N18.3 Chronic kidney disease, stage 3
0.984 0.016 0.000
N40 Hyperplasia of prostate
0.000 0.019 0.981
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.977 0.023 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.976 0.024 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.024 0.976
M06.3 Rheumatoid nodule
0.000 0.026 0.974
K90 Intestinal malabsorption
0.973 0.027 0.000
E21.3 Hyperparathyroidism, unspecified
0.973 0.027 0.000
N18.4 Chronic kidney disease, stage 4
0.967 0.033 0.000
H33 Retinal detachments and breaks
0.966 0.034 0.000
E07 Other disorders of thyroid
0.964 0.036 0.000
H00.1 Chalazion
0.000 0.036 0.964
H47 Other disorders of optic [2nd] nerve and visual pathways
0.964 0.036 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.964 0.036 0.000
L10-L14 Bullous disorders
0.963 0.037 0.000
M05 Seropositive rheumatoid arthritis
0.039 0.037 0.924
E14.3 With ophthalmic complications
0.962 0.038 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.001 0.039 0.960
N05.2 Diffuse membranous glomerulonephritis
0.960 0.040 0.000
H33.3 Retinal breaks without detachment
0.959 0.041 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.041 0.959
N40-N51 Diseases of male genital organs
0.000 0.041 0.959
D61 Other aplastic anaemias
0.957 0.043 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.045 0.955
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.954 0.046 0.000
D50-D53 Nutritional anaemias
0.953 0.047 0.000
L50-L54 Urticaria and erythema
0.951 0.049 0.000
E10.4 With neurological complications
0.950 0.050 0.000
E11.1 With ketoacidosis
0.950 0.050 0.000
G51 Facial nerve disorders
0.947 0.053 0.000
E06 Thyroiditis
0.947 0.053 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.947 0.053 0.000
D80-D89 Certain disorders involving the immune mechanism
0.944 0.056 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.942 0.057 0.001
C83 Diffuse non-Hodgkin's lymphoma
0.940 0.060 0.000
L13 Other bullous disorders
0.940 0.060 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.938 0.062 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.937 0.063 0.000
M06.34 Rheumatoid nodule (Hand)
0.000 0.063 0.937
E10.2 With renal complications
0.936 0.064 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.064 0.935
C83.3 Large cell (diffuse)
0.931 0.069 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.070 0.930
D61.9 Aplastic anaemia, unspecified
0.928 0.072 0.000
Chapter II Neoplasms
0.928 0.072 0.000
K90-K93 Other diseases of the digestive system
0.926 0.074 0.000
L13.0 Dermatitis herpetiformis
0.923 0.077 0.000
Chapter XI Diseases of the digestive system
0.921 0.079 0.000
K70-K77 Diseases of liver
0.918 0.082 0.000
E07.8 Other specified disorders of thyroid
0.917 0.083 0.000
E06.3 Autoimmune thyroiditis
0.916 0.084 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.084 0.916
Q38-Q45 Other congenital malformations of the digestive system
0.911 0.089 0.000
G30-G32 Other degenerative diseases of the nervous system
0.909 0.091 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.904 0.095 0.000
G59.0 Diabetic mononeuropathy
0.900 0.100 0.000
E28 Ovarian dysfunction
0.897 0.103 0.000
K75 Other inflammatory liver diseases
0.897 0.103 0.000
K74 Fibrosis and cirrhosis of liver
0.892 0.108 0.000
E10.5 With peripheral circulatory complications
0.891 0.109 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.889 0.111 0.000
E11.2 With renal complications
0.889 0.111 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.888 0.112 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.117 0.883
N04.2 Diffuse membranous glomerulonephritis
0.883 0.117 0.000
Q60-Q64 Congenital malformations of the urinary system
0.882 0.118 0.000
N03 Chronic nephritic syndrome
0.881 0.119 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.878 0.122 0.000
H06.2 Dysthyroid exophthalmos
0.878 0.122 0.000
L53 Other erythematous conditions
0.876 0.124 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.125 0.875
K75.4 Autoimmune hepatitis
0.874 0.126 0.000
M06.0 Seronegative rheumatoid arthritis
0.000 0.127 0.873
C85.1 B-cell lymphoma, unspecified
0.873 0.127 0.000
N45 Orchitis and epididymitis
0.000 0.128 0.872
G51.0 Bell's palsy
0.871 0.129 0.000
C15-C26 Malignant neoplasms of digestive organs
0.869 0.131 0.000
H43-H45 Disorders of vitreous body and globe
0.868 0.132 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.868 0.132 0.000
N05.1 Focal and segmental glomerular lesions
0.867 0.133 0.000
H47.2 Optic atrophy
0.867 0.133 0.000
L52 Erythema nodosum
0.867 0.133 0.000
D50 Iron deficiency anaemia
0.865 0.135 0.000
N04.1 Focal and segmental glomerular lesions
0.864 0.136 0.000
H00 Hordeolum and chalazion
0.090 0.136 0.774
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.861 0.139 0.000
Chapter I Certain infectious and parasitic diseases
0.861 0.139 0.000
C81 Hodgkin's disease
0.860 0.140 0.000
H46 Optic neuritis
0.859 0.141 0.000
K74.6 Other and unspecified cirrhosis of liver
0.858 0.142 0.000
N17 Acute renal failure
0.858 0.142 0.000
G31.8 Other specified degenerative diseases of nervous system
0.856 0.144 0.000
H05 Disorders of orbit
0.854 0.146 0.000
Q50-Q56 Congenital malformations of genital organs
0.853 0.147 0.000
E27.8 Other specified disorders of adrenal gland
0.853 0.147 0.000
H33.1 Retinoschisis and retinal cysts
0.852 0.148 0.000
K90.9 Intestinal malabsorption, unspecified
0.848 0.152 0.000
E14.8 With unspecified complications
0.847 0.153 0.000
Q00-Q07 Congenital malformations of the nervous system
0.843 0.157 0.000
H47.3 Other disorders of optic disk
0.843 0.157 0.000
H34.2 Other retinal artery occlusions
0.842 0.158 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.839 0.161 0.000
E28.2 Polycystic ovarian syndrome
0.836 0.164 0.000
D51 Vitamin B12 deficiency anaemia
0.836 0.164 0.000
G51.9 Disorder of facial nerve, unspecified
0.835 0.165 0.000
L40.3 Pustulosis palmaris et plantaris
0.834 0.166 0.000
H43 Disorders of vitreous body
0.829 0.171 0.000
M06.4 Inflammatory polyarthropathy
0.000 0.171 0.829
E10.7 With multiple complications
0.828 0.172 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.828 0.172 0.000
L44 Other papulosquamous disorders
0.824 0.176 0.000
C20 Malignant neoplasm of rectum
0.822 0.178 0.000
B15-B19 Viral hepatitis
0.820 0.180 0.000
C91 Lymphoid leukaemia
0.818 0.182 0.000
G56.1 Other lesions of median nerve
0.818 0.182 0.000
E07.9 Disorder of thyroid, unspecified
0.816 0.184 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.814 0.186 0.000
E10.0 With coma
0.810 0.190 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.191 0.809
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.191 0.809
D80 Immunodeficiency with predominantly antibody defects
0.807 0.193 0.000
K73 Chronic hepatitis, not elsewhere classified
0.807 0.193 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.805 0.195 0.000
C84.5 Other and unspecified T-cell lymphomas
0.804 0.196 0.000
H47.1 Papilloedema, unspecified
0.803 0.197 0.000
E14.4 With neurological complications
0.803 0.197 0.000
H30 Chorioretinal inflammation
0.802 0.198 0.000
Q43 Other congenital malformations of intestine
0.801 0.199 0.000
G56.4 Causalgia
0.801 0.199 0.000
L40.1 Generalised pustular psoriasis
0.801 0.199 0.000
E24 Cushing's syndrome
0.800 0.200 0.000
N48 Other disorders of penis
0.000 0.201 0.799
E27.9 Disorder of adrenal gland, unspecified
0.797 0.203 0.000
L53.9 Erythematous condition, unspecified
0.797 0.203 0.000
D68 Other coagulation defects
0.795 0.205 0.000
H47.0 Disorders of optic nerve, not elsewhere classified
0.795 0.205 0.000
E14.1 With ketoacidosis
0.795 0.205 0.000
L20-L30 Dermatitis and eczema
0.794 0.206 0.000
D50.9 Iron deficiency anaemia, unspecified
0.794 0.206 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.001 0.207 0.792
E10.8 With unspecified complications
0.792 0.208 0.000
C81.1 Nodular sclerosis
0.791 0.209 0.000
C34 Malignant neoplasm of bronchus and lung
0.790 0.210 0.000
H05.2 Exophthalmic conditions
0.787 0.213 0.000
M20 Acquired deformities of fingers and toes
0.001 0.215 0.785
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.215 0.785
B25-B34 Other viral diseases
0.781 0.219 0.000
K75.8 Other specified inflammatory liver diseases
0.780 0.220 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.779 0.221 0.000
E31 Polyglandular dysfunction
0.779 0.221 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.778 0.222 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.776 0.224 0.000
N18.1 Chronic kidney disease, stage 1
0.776 0.224 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.000 0.225 0.775
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.775 0.225 0.000
D64.3 Other sideroblastic anaemias
0.775 0.225 0.000
L53.0 Toxic erythema
0.775 0.225 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.774 0.226 0.000
C83.1 Small cleaved cell (diffuse)
0.774 0.226 0.000
N05.8 Other
0.773 0.227 0.000
C83.7 Burkitt's tumour
0.772 0.228 0.000
Q50.4 Embryonic cyst of Fallopian tube
0.771 0.229 0.000
N18.8 Other chronic renal failure
0.771 0.229 0.000
C04 Malignant neoplasm of floor of mouth
0.770 0.230 0.000
D82 Immunodeficiency associated with other major defects
0.770 0.230 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.769 0.231 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.768 0.232 0.000
G56.8 Other mononeuropathies of upper limb
0.768 0.232 0.000
C25 Malignant neoplasm of pancreas
0.767 0.233 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.237 0.763
Q60 Renal agenesis and other reduction defects of kidney
0.762 0.238 0.000
E13 Other specified diabetes mellitus
0.761 0.239 0.000
M12 Other specific arthropathies
0.055 0.239 0.706
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.240 0.760
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.240 0.760
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.757 0.243 0.000
K72 Hepatic failure, not elsewhere classified
0.756 0.244 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.756 0.244 0.000
E21.2 Other hyperparathyroidism
0.754 0.246 0.000
D64.8 Other specified anaemias
0.753 0.247 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.752 0.248 0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.751 0.249 0.000
B18 Chronic viral hepatitis
0.751 0.249 0.000
E34 Other endocrine disorders
0.750 0.250 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.001 0.250 0.749
N17.9 Acute renal failure, unspecified
0.750 0.250 0.000
D86 Sarcoidosis
0.748 0.252 0.000
E22 Hyperfunction of pituitary gland
0.744 0.256 0.000
K71 Toxic liver disease
0.744 0.256 0.000
N48.0 Leukoplakia of penis
0.000 0.258 0.742
C91.1 Chronic lymphocytic leukaemia
0.742 0.258 0.000
E14.5 With peripheral circulatory complications
0.741 0.259 0.000
N44 Torsion of testis
0.000 0.259 0.740
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.260 0.740
L10 Pemphigus
0.740 0.260 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.740 0.260 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.739 0.261 0.000
B34 Viral infection of unspecified site
0.739 0.261 0.000
K74.5 Biliary cirrhosis, unspecified
0.739 0.261 0.000
N04.0 Minor glomerular abnormality
0.739 0.261 0.000
C25.9 Pancreas, unspecified
0.737 0.263 0.000
Q43.9 Congenital malformation of intestine, unspecified
0.737 0.263 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.736 0.264 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.736 0.264 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.736 0.264 0.000
B17 Other acute viral hepatitis
0.735 0.265 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.734 0.266 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.000 0.268 0.732
Q61 Cystic kidney disease
0.732 0.268 0.000
D68.0 Von Willebrand's disease
0.732 0.268 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.001 0.269 0.730
E02 Subclinical iodine-deficiency hypothyroidism
0.730 0.270 0.000
D68.6 Other Thrombophilia
0.729 0.271 0.000
H43.9 Disorder of vitreous body, unspecified
0.729 0.271 0.000
C22.9 Liver, unspecified
0.729 0.271 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.728 0.272 0.000
D52 Folate deficiency anaemia
0.726 0.274 0.000
C95 Leukaemia of unspecified cell type
0.726 0.274 0.000
H00.0 Hordeolum and other deep inflammation of eyelid
0.020 0.275 0.705
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.723 0.277 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.723 0.277 0.000
L27 Dermatitis due to substances taken internally
0.723 0.277 0.000
E11.6 With other specified complications
0.722 0.278 0.000
E11.5 With peripheral circulatory complications
0.722 0.278 0.000
H43.3 Other vitreous opacities
0.721 0.279 0.000
D83 Common variable immunodeficiency
0.721 0.279 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.721 0.279 0.001
C23 Malignant neoplasm of gallbladder
0.720 0.280 0.000
D55-D59 Haemolytic anaemias
0.720 0.280 0.000
E40-E46 Malnutrition
0.720 0.280 0.000
D68.8 Other specified coagulation defects
0.719 0.281 0.000
D61.0 Constitutional aplastic anaemia
0.717 0.283 0.000
E14.2 Withrenal complications
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.717 0.283 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.717 0.283 0.000
N06 Isolated proteinuria with specified morphological lesion
0.717 0.283 0.000
N01 Rapidly progressive nephritic syndrome
0.717 0.283 0.000
N00 Acute nephritic syndrome
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.717 0.283 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.717 0.283 0.000
E32 Diseases of thymus
0.717 0.283 0.000
E30 Disorders of puberty, not elsewhere classified
0.717 0.283 0.000
E25 Adrenogenital disorders
0.717 0.283 0.000
L41 Parapsoriasis
0.717 0.283 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.717 0.283 0.000
N04.8 Other
0.717 0.283 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.717 0.283 0.000
N04.6 Dense deposit disease
0.717 0.283 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.717 0.283 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.717 0.283 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.000 0.284 0.716
M06.1 Adult-onset Still's disease
0.000 0.284 0.716
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.716 0.284 0.000
E15 Nondiabetic hypoglycaemic coma
0.715 0.285 0.000
E11.7 With multiple complications
0.715 0.285 0.000
E27.5 Adrenomedullary hyperfunction
0.714 0.286 0.000
E27.0 Other adrenocortical overactivity
0.714 0.286 0.000
E03.8 Other specified hypothyroidism
0.714 0.286 0.000
D64.4 Congenital dyserythropoietic anaemia
0.714 0.286 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.714 0.286 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.714 0.286 0.000
D64.0 Hereditary sideroblastic anaemia
0.714 0.286 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.713 0.286 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.713 0.286 0.000
E16.4 Abnormal secretion of gastrin
0.713 0.286 0.000
E16.3 Increased secretion of glucagon
0.713 0.286 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.713 0.287 0.000
H34.0 Transient retinal artery occlusion
0.712 0.288 0.000
D70 Agranulocytosis
0.712 0.288 0.000
C91.9 Lymphoid leukaemia, unspecified
0.712 0.288 0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.000 0.288 0.711
E06.5 Other chronic thyroiditis
0.711 0.289 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.710 0.290 0.000
C88 Malignant immunoproliferative diseases
0.710 0.290 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.066 0.291 0.644
M08 Juvenile arthritis
0.066 0.291 0.644
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.697 0.292 0.011
N03.1 Focal and segmental glomerular lesions
0.707 0.292 0.000
N02 Recurrent and persistent haematuria
0.707 0.293 0.000
E14.7 With multiple complications
0.707 0.293 0.000
E14.0 With coma
0.707 0.293 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.707 0.293 0.000
N05.6 Dense deposit disease
0.706 0.293 0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.706 0.293 0.000
N05.0 Minor glomerular abnormality
0.706 0.293 0.000
E21.4 Other specified disorders of parathyroid gland
0.705 0.295 0.000
G51.3 Clonic hemifacial spasm
0.705 0.295 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.295 0.705
B65-B83 Helminthiases
0.704 0.296 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.704 0.296 0.000
K74.3 Primary biliary cirrhosis
0.704 0.296 0.000
N03.8 Other
0.703 0.297 0.000
B34.9 Viral infection, unspecified
0.703 0.297 0.000
L11 Other acantholytic disorders
0.702 0.298 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.702 0.298 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.701 0.299 0.000
Q04 Other congenital malformations of brain
0.701 0.299 0.000
Q35-Q37 Cleft lip and cleft palate
0.701 0.299 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.701 0.299 0.000
C84.4 Peripheral T-cell lymphoma
0.700 0.299 0.000
C34.9 Bronchus or lung, unspecified
0.700 0.300 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.700 0.300 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.700 0.300 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.700 0.300 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.700 0.300 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.301 0.699
L44.0 Pityriasis rubra pilaris
0.699 0.301 0.000
E11.8 With unspecified complications
0.698 0.301 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.301 0.698
M06.38 Rheumatoid nodule (Other)
0.000 0.301 0.698
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.301 0.698
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.301 0.698
M06.33 Rheumatoid nodule (Forearm)
0.000 0.301 0.698
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.301 0.698
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.301 0.698
K90.3 Pancreatic steatorrhoea
0.698 0.302 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.698 0.302 0.000
K90.1 Tropical sprue
0.698 0.302 0.000
Q03 Congenital hydrocephalus
0.695 0.305 0.000
H43.1 Vitreous haemorrhage
0.695 0.305 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.694 0.305 0.000
N03.9 Unspecified
0.695 0.305 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.694 0.306 0.000
C13 Malignant neoplasm of hypopharynx
0.693 0.307 0.000
K90.8 Other intestinal malabsorption
0.693 0.307 0.000
H34.1 Central retinal artery occlusion
0.693 0.307 0.000
C51-C58 Malignant neoplasms of female genital organs
0.693 0.307 0.000
N05.9 Unspecified
0.692 0.308 0.000
E07.1 Dyshormogenetic goitre
0.691 0.309 0.000
E07.0 Hypersecretion of calcitonin
0.691 0.309 0.000
K72.9 Hepatic failure, unspecified
0.691 0.309 0.000
H47.7 Disorder of visual pathways, unspecified
0.691 0.309 0.000
H47.6 Disorders of visual cortex
0.691 0.309 0.000
H47.5 Disorders of other visual pathways
0.691 0.309 0.000
H47.4 Disorders of optic chiasm
0.691 0.309 0.000
H35 Other retinal disorders
0.691 0.309 0.000
H33.4 Traction detachment of retina
0.691 0.309 0.000
L14 Bullous disorders in diseases classified elsewhere
0.690 0.309 0.000
L28 Lichen simplex chronicus and prurigo
0.690 0.309 0.000
M05.8 Other seropositive rheumatoid arthritis
0.028 0.310 0.662
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.028 0.310 0.662
M05.2 Rheumatoid vasculitis
0.028 0.310 0.662
M05.1 Rheumatoid lung disease
0.028 0.310 0.662
M05.0 Felty's syndrome
0.028 0.310 0.662
L43 Lichen planus
0.690 0.310 0.000
H34.9 Retinal vascular occlusion, unspecified
0.690 0.310 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.001 0.311 0.688
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.001 0.311 0.688
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.001 0.311 0.688
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.001 0.311 0.688
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.001 0.311 0.688
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.312 0.687
B18.2 Chronic viral hepatitis C
0.688 0.312 0.000
D61.8 Other specified aplastic anaemias
0.686 0.314 0.000
D61.3 Idiopathic aplastic anaemia
0.686 0.314 0.000
D61.2 Aplastic anaemia due to other external agents
0.686 0.314 0.000
G31.2 Degeneration of nervous system due to alcohol
0.686 0.314 0.000
E20 Hypoparathyroidism
0.685 0.315 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.684 0.316 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.684 0.316 0.000
C94 Other leukaemias of specified cell type
0.684 0.316 0.000
G11 Hereditary ataxia
0.684 0.316 0.000
C04.9 Floor of mouth, unspecified
0.684 0.316 0.000
C56 Malignant neoplasm of ovary
0.683 0.317 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.682 0.318 0.000
B02 Zoster [herpes zoster]
0.682 0.318 0.000
C81.2 Mixed cellularity
0.682 0.318 0.000
L54 Erythema in diseases classified elsewhere
0.681 0.318 0.000
C34.3 Lower lobe, bronchus or lung
0.682 0.318 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.680 0.320 0.000
G51.4 Facial myokymia
0.679 0.321 0.000
G51.2 Melkersson's syndrome
0.679 0.321 0.000
G51.1 Geniculate ganglionitis
0.679 0.321 0.000
M15-M19 Arthrosis
0.679 0.321 0.000
E06.4 Drug-induced thyroiditis
0.679 0.321 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.679 0.321 0.000
E06.1 Subacute thyroiditis
0.679 0.321 0.000
E06.0 Acute thyroiditis
0.679 0.321 0.000
C85.0 Lymphosarcoma
0.679 0.321 0.000
D86.3 Sarcoidosis of skin
0.678 0.322 0.000
M60-M63 Disorders of muscles
0.674 0.322 0.004
D81 Combined immunodeficiencies
0.677 0.323 0.000
D73 Diseases of spleen
0.676 0.324 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.675 0.324 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.675 0.325 0.000
E10.6 With other specified complications
0.675 0.325 0.000
D69 Purpura and other haemorrhagic conditions
0.675 0.325 0.000
C34.2 Middle lobe, bronchus or lung
0.675 0.325 0.000
Q60.2 Renal agenesis, unspecified
0.674 0.326 0.000
C83.6 Undifferentiated (diffuse)
0.674 0.326 0.000
C83.5 Lymphoblastic (diffuse)
0.674 0.326 0.000
C83.4 Immunoblastic (diffuse)
0.674 0.326 0.000
C83.2 Mixed small and large cell (diffuse)
0.674 0.326 0.000
C12 Malignant neoplasm of pyriform sinus
0.674 0.326 0.000
L13.9 Bullous disorder, unspecified
0.674 0.326 0.000
L13.8 Other specified bullous disorders
0.674 0.326 0.000
L13.1 Subcorneal pustular dermatitis
0.674 0.326 0.000
E16.1 Other hypoglycaemia
0.673 0.327 0.000
B00 Herpesviral [herpes simplex] infections
0.673 0.327 0.000
G59.8 Other mononeuropathies in diseases classified elsewhere
0.672 0.328 0.000
D72 Other disorders of white blood cells
0.671 0.329 0.000
N02.2 Diffuse membranous glomerulonephritis
0.671 0.329 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.669 0.331 0.000
D53 Other nutritional anaemias
0.668 0.331 0.000
C38.4 Pleura
0.668 0.332 0.000
G51.8 Other disorders of facial nerve
0.666 0.334 0.000
C86 Other specified types of T/NK-cell lymphoma
0.666 0.334 0.000
D84 Other immunodeficiencies
0.665 0.335 0.000
E27.2 Addisonian crisis
0.665 0.335 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.664 0.336 0.000
E24.0 Pituitary-dependent Cushing's disease
0.664 0.336 0.000
B17.1 Acute hepatitis C
0.663 0.336 0.000
N48.9 Disorder of penis, unspecified
0.000 0.337 0.663
Q55 Other congenital malformations of male genital organs
0.662 0.338 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.662 0.338 0.000
M18 Arthrosis of first carpometacarpal joint
0.661 0.339 0.000
D50.8 Other iron deficiency anaemias
0.661 0.339 0.000
B35-B49 Mycoses
0.660 0.340 0.000
H30.9 Chorioretinal inflammation, unspecified
0.660 0.340 0.000
K77 Liver disorders in diseases classified elsewhere
0.658 0.342 0.000
D50.1 Sideropenic dysphagia
0.658 0.342 0.000
C38.3 Mediastinum, part unspecified
0.656 0.343 0.000
H05.0 Acute inflammation of orbit
0.656 0.344 0.000
N49.2 Inflammatory disorders of scrotum
0.000 0.344 0.656
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.655 0.345 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.653 0.347 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.653 0.347 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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