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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs522162
log Bayes Factor = 27.0343
Chromosome 6   position 31,919,917  (GRCh37) Explore rs522162 on Ensembl!
Variant rs522162 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.002 0.998
E10.3 With ophthalmic complications
0.000 0.008 0.992
E11 Non-insulin-dependent diabetes mellitus
0.000 0.019 0.981
E05.9 Thyrotoxicosis, unspecified
0.000 0.027 0.973
E11.3 With ophthalmic complications
0.000 0.043 0.957
E10.1 With ketoacidosis
0.000 0.047 0.953
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.050 0.950
E65-E68 Obesity and other hyperalimentation
0.000 0.050 0.950
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.059 0.941
E66 Obesity
0.000 0.089 0.911
E66.8 Other obesity
0.000 0.094 0.906
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.115 0.885
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.134 0.866
E10.5 With peripheral circulatory complications
0.000 0.134 0.866
E11.9 Without complications
0.000 0.141 0.859
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.150 0.850
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.159 0.841
E11.5 With peripheral circulatory complications
0.000 0.184 0.816
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.192 0.808
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.199 0.801
M06 Other rheumatoid arthritis
0.000 0.215 0.785
E10.4 With neurological complications
0.000 0.226 0.774
E06 Thyroiditis
0.000 0.227 0.773
E10.2 With renal complications
0.000 0.233 0.767
E11.2 With renal complications
0.000 0.236 0.764
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.260 0.740
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E05.8 Other thyrotoxicosis
0.000 0.285 0.715
E05.5 Thyroid crisis or storm
0.000 0.285 0.715
E05.4 Thyrotoxicosis factitia
0.000 0.285 0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.285 0.715
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.285 0.715
M06.0 Seronegative rheumatoid arthritis
0.000 0.292 0.708
E65 Localised adiposity
0.000 0.295 0.705
E11.7 With multiple complications
0.000 0.296 0.704
E13 Other specified diabetes mellitus
0.000 0.297 0.702
E11.0 With coma
0.000 0.299 0.701
E50-E64 Other nutritional deficiencies
0.000 0.308 0.692
E11.6 With other specified complications
0.000 0.317 0.682
E67 Other hyperalimentation
0.000 0.319 0.681
E68 Sequelae of hyperalimentation
0.000 0.319 0.681
E10.8 With unspecified complications
0.000 0.333 0.667
E66.1 Drug-induced obesity
0.000 0.346 0.653
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.346 0.653
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.369 0.630
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.373 0.627
E11.8 With unspecified complications
0.000 0.378 0.622
E06.3 Autoimmune thyroiditis
0.000 0.382 0.618
E11.1 With ketoacidosis
0.000 0.385 0.615
E40-E46 Malnutrition
0.000 0.385 0.615
E66.0 Obesity due to excess calories
0.000 0.385 0.614
E14 Unspecified diabetes mellitus
0.000 0.388 0.612
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.389 0.611
M06.3 Rheumatoid nodule
0.000 0.399 0.600
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.406 0.594
E11.4 With neurological complications
0.000 0.409 0.591
M06.8 Other specified rheumatoid arthritis
0.000 0.437 0.562
M06.2 Rheumatoid bursitis
0.000 0.437 0.562
M06.1 Adult-onset Still's disease
0.000 0.437 0.562
E06.5 Other chronic thyroiditis
0.000 0.446 0.554
E06.4 Drug-induced thyroiditis
0.000 0.446 0.554
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.446 0.554
E06.1 Subacute thyroiditis
0.000 0.446 0.554
E06.0 Acute thyroiditis
0.000 0.446 0.554
E06.9 Thyroiditis, unspecified
0.000 0.456 0.544
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.492 0.508
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.492 0.508
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.492 0.508
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.492 0.508
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.492 0.508
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.492 0.508
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.492 0.508
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.492 0.508
E20-E35 Disorders of other endocrine glands
0.000 0.495 0.505
E13.8 With unspecified complications
0.000 0.496 0.504
E13.7 With multiple complications
0.000 0.496 0.504
E13.6 With other specified complications
0.000 0.496 0.504
E13.5 With peripheral circulatory complications
0.000 0.496 0.504
E13.4 With neurological complications
0.000 0.496 0.504
E13.3 With ophthalmic complications
0.000 0.496 0.504
E13.2 With renal complications
0.000 0.496 0.504
E13.1 With ketoacidosis
0.000 0.496 0.504
E13.0 With coma
0.000 0.496 0.504
M06.4 Inflammatory polyarthropathy
0.000 0.496 0.503
E55 Vitamin D deficiency
0.000 0.504 0.496
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.504 0.496
E63 Other nutritional deficiencies
0.000 0.504 0.496
E56 Other vitamin deficiencies
0.000 0.504 0.496
E51 Thiamine deficiency
0.000 0.504 0.496
E50 Vitamin A deficiency
0.000 0.504 0.496
E60 Dietary zinc deficiency
0.000 0.504 0.496
E59 Dietary selenium deficiency
0.000 0.504 0.496
E58 Dietary calcium deficiency
0.000 0.504 0.496
E54 Ascorbic acid deficiency
0.000 0.504 0.496
E52 Niacin deficiency [pellagra]
0.000 0.504 0.496
E13.9 Without complications
0.000 0.511 0.489
E67.8 Other specified hyperalimentation
0.000 0.511 0.488
E67.3 Hypervitaminosis D
0.000 0.511 0.488
E67.2 Megavitamin-B6 syndrome
0.000 0.511 0.488
E67.1 Hypercarotenaemia
0.000 0.511 0.488
E67.0 Hypervitaminosis A
0.000 0.511 0.488
E03.8 Other specified hypothyroidism
0.001 0.512 0.488
E61 Deficiency of other nutrient elements
0.000 0.513 0.487
E53 Deficiency of other B group vitamins
0.000 0.519 0.481
E07 Other disorders of thyroid
0.000 0.530 0.469
E15 Nondiabetic hypoglycaemic coma
0.000 0.531 0.468
M06.34 Rheumatoid nodule (Hand)
0.000 0.531 0.468
E27 Other disorders of adrenal gland
0.000 0.536 0.464
E14.3 With ophthalmic complications
0.000 0.545 0.455
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.559 0.441
E45 Retarded development following protein-energy malnutrition
0.000 0.559 0.441
E43 Unspecified severe protein-energy malnutrition
0.000 0.559 0.441
E42 Marasmic kwashiorkor
0.000 0.559 0.441
E41 Nutritional marasmus
0.000 0.559 0.441
E40 Kwashiorkor
0.000 0.559 0.441
E14.8 With unspecified complications
0.000 0.561 0.439
E14.7 With multiple complications
0.000 0.561 0.439
E14.6 With other specified complications
0.000 0.561 0.439
E14.5 With peripheral circulatory complications
0.000 0.561 0.439
E14.4 With neurological complications
0.000 0.561 0.439
E14.1 With ketoacidosis
0.000 0.561 0.439
E14.0 With coma
0.000 0.561 0.439
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.569 0.430
M06.38 Rheumatoid nodule (Other)
0.000 0.569 0.430
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.569 0.430
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.569 0.430
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.569 0.430
M06.33 Rheumatoid nodule (Forearm)
0.000 0.569 0.430
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.569 0.430
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.569 0.430
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.569 0.430
E27.1 Primary adrenocortical insufficiency
0.000 0.590 0.410
E16 Other disorders of pancreatic internal secretion
0.000 0.594 0.405
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.596 0.404
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.596 0.403
M06.18 Adult-onset Still's disease (Other)
0.000 0.596 0.403
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.596 0.403
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.596 0.403
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.596 0.403
M06.14 Adult-onset Still's disease (Hand)
0.000 0.596 0.403
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.596 0.403
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.596 0.403
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.596 0.403
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.596 0.403
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.596 0.403
M06.28 Rheumatoid bursitis (Other)
0.000 0.596 0.403
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.596 0.403
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.596 0.403
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.596 0.403
M06.24 Rheumatoid bursitis (Hand)
0.000 0.596 0.403
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.596 0.403
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.596 0.403
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.596 0.403
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.596 0.403
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.596 0.403
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.596 0.403
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.596 0.403
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.596 0.403
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.596 0.403
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.596 0.403
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.596 0.403
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.596 0.403
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.596 0.403
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.596 0.403
E04 Other non-toxic goitre
0.000 0.596 0.404
E14.9 Without complications
0.000 0.601 0.399
E20 Hypoparathyroidism
0.000 0.603 0.396
E27.8 Other specified disorders of adrenal gland
0.000 0.609 0.391
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.621 0.379
E14.2 Withrenal complications
0.000 0.636 0.363
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.637 0.362
E32 Diseases of thymus
0.000 0.637 0.362
E31 Polyglandular dysfunction
0.000 0.637 0.362
E30 Disorders of puberty, not elsewhere classified
0.000 0.637 0.362
E22 Hyperfunction of pituitary gland
0.000 0.637 0.362
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.639 0.361
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.639 0.361
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.639 0.361
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.639 0.361
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.639 0.361
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.639 0.361
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.639 0.361
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.639 0.361
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.639 0.361
M05-M14 Inflammatory polyarthropathies
0.002 0.640 0.358
E55.9 Vitamin D deficiency, unspecified
0.000 0.644 0.356
E55.0 Rickets, active
0.000 0.644 0.356
E50.9 Vitamin A deficiency, unspecified
0.000 0.644 0.356
E50.8 Other manifestations of vitamin A deficiency
0.000 0.644 0.356
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.644 0.356
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.644 0.356
E50.5 Vitamin A deficiency with night blindness
0.000 0.644 0.356
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.644 0.356
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.644 0.356
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.644 0.356
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.644 0.356
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.644 0.356
E51.9 Thiamine deficiency, unspecified
0.000 0.644 0.356
E51.8 Other manifestations of thiamine deficiency
0.000 0.644 0.356
E51.2 Wernicke's encephalopathy
0.000 0.644 0.356
E51.1 Beriberi
0.000 0.644 0.356
E56.9 Vitamin deficiency, unspecified
0.000 0.644 0.356
E56.8 Deficiency of other vitamins
0.000 0.644 0.356
E56.1 Deficiency of vitamin K
0.000 0.644 0.356
E56.0 Deficiency of vitamin E
0.000 0.644 0.356
E63.9 Nutritional deficiency, unspecified
0.000 0.644 0.356
E63.8 Other specified nutritional deficiencies
0.000 0.644 0.356
E63.1 Imbalance of constituents of food intake
0.000 0.644 0.356
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.644 0.356
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.644 0.356
E64.8 Sequelae of other nutritional deficiencies
0.000 0.644 0.356
E64.3 Sequelae of rickets
0.000 0.644 0.356
E64.2 Sequelae of vitamin C deficiency
0.000 0.644 0.356
E64.1 Sequelae of vitamin A deficiency
0.000 0.644 0.356
E64.0 Sequelae of protein-energy malnutrition
0.000 0.644 0.356
E27.2 Addisonian crisis
0.000 0.649 0.351
E53.8 Deficiency of other specified B group vitamins
0.000 0.651 0.349
E61.9 Deficiency of nutrient element, unspecified
0.000 0.651 0.349
E61.8 Deficiency of other specified nutrient elements
0.000 0.651 0.349
E61.7 Deficiency of multiple nutrient elements
0.000 0.651 0.349
E61.6 Vanadium deficiency
0.000 0.651 0.349
E61.5 Molybdenum deficiency
0.000 0.651 0.349
E61.4 Chromium deficiency
0.000 0.651 0.349
E61.3 Manganese deficiency
0.000 0.651 0.349
E61.2 Magnesium deficiency
0.000 0.651 0.349
E61.0 Copper deficiency
0.000 0.651 0.349
E53.1 Pyridoxine deficiency
0.000 0.655 0.345
E53.0 Riboflavin deficiency
0.000 0.655 0.345
E21.3 Hyperparathyroidism, unspecified
0.000 0.659 0.341
E61.1 Iron deficiency
0.000 0.660 0.340
E46 Unspecified protein-energy malnutrition
0.000 0.661 0.339
E07.1 Dyshormogenetic goitre
0.000 0.663 0.337
E07.0 Hypersecretion of calcitonin
0.000 0.663 0.337
E27.5 Adrenomedullary hyperfunction
0.000 0.667 0.333
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.667 0.333
E27.0 Other adrenocortical overactivity
0.000 0.667 0.333
E28 Ovarian dysfunction
0.000 0.671 0.329
L40.9 Psoriasis, unspecified
0.000 0.674 0.326
L40 Psoriasis
0.000 0.675 0.325
E53.9 Vitamin B deficiency, unspecified
0.000 0.675 0.325
L40.5 Arthropathic psoriasis
0.000 0.675 0.325
E04.0 Non-toxic diffuse goitre
0.000 0.681 0.319
E20.9 Hypoparathyroidism, unspecified
0.000 0.681 0.319
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.682 0.318
M05 Seropositive rheumatoid arthritis
0.001 0.682 0.317
E44.1 Mild protein-energy malnutrition
0.000 0.684 0.316
E44.0 Moderate protein-energy malnutrition
0.000 0.684 0.316
E26 Hyperaldosteronism
0.000 0.685 0.315
E07.8 Other specified disorders of thyroid
0.001 0.694 0.306
M07 Psoriatic and enteropathic arthropathies
0.001 0.696 0.303
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.001 0.698 0.302
E04.2 Non-toxic multinodular goitre
0.000 0.699 0.301
E25 Adrenogenital disorders
0.001 0.703 0.296
E24 Cushing's syndrome
0.000 0.704 0.296
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.706 0.294
S61.0 Open wound of finger(s) without damage to nail
0.294 0.706 0.000
E22.1 Hyperprolactinaemia
0.000 0.707 0.292
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.709 0.291
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.709 0.291
E16.4 Abnormal secretion of gastrin
0.000 0.709 0.291
E16.3 Increased secretion of glucagon
0.000 0.709 0.291
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.710 0.290
E21.4 Other specified disorders of parathyroid gland
0.000 0.710 0.290
E21.2 Other hyperparathyroidism
0.000 0.710 0.290
E04.8 Other specified non-toxic goitre
0.000 0.710 0.289
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.712 0.287
E29 Testicular dysfunction
0.000 0.713 0.287
E20.8 Other hypoparathyroidism
0.000 0.715 0.284
E20.1 Pseudohypoparathyroidism
0.000 0.715 0.284
E20.0 Idiopathic hypoparathyroidism
0.000 0.715 0.284
E23 Hypofunction and other disorders of pituitary gland
0.000 0.725 0.274
L40.0 Psoriasis vulgaris
0.000 0.727 0.273
E16.1 Other hypoglycaemia
0.000 0.731 0.269
M07.3 Other psoriatic arthropathies
0.000 0.737 0.263
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.740 0.260
E22.8 Other hyperfunction of pituitary gland
0.000 0.740 0.260
E30.9 Disorder of puberty, unspecified
0.000 0.740 0.260
E30.8 Other disorders of puberty
0.000 0.740 0.260
E30.1 Precocious puberty
0.000 0.740 0.260
E30.0 Delayed puberty
0.000 0.740 0.260
E31.9 Polyglandular dysfunction, unspecified
0.000 0.740 0.260
E31.8 Other polyglandular dysfunction
0.000 0.740 0.260
E31.1 Polyglandular hyperfunction
0.000 0.740 0.260
E31.0 Autoimmune polyglandular failure
0.000 0.740 0.260
E32.9 Disease of thymus, unspecified
0.000 0.740 0.260
E32.8 Other diseases of thymus
0.000 0.740 0.260
E32.1 Abscess of thymus
0.000 0.740 0.260
E32.0 Persistent hyperplasia of thymus
0.000 0.740 0.260
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.740 0.260
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.740 0.260
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.740 0.260
M12 Other specific arthropathies
0.002 0.742 0.257
M09 Juvenile arthritis in diseases classified elsewhere
0.002 0.742 0.257
M08 Juvenile arthritis
0.002 0.742 0.257
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.744 0.256
M14 Arthropathies in other diseases classified elsewhere
0.001 0.746 0.252
E16.2 Hypoglycaemia, unspecified
0.000 0.748 0.252
E34 Other endocrine disorders
0.001 0.756 0.243
L40.8 Other psoriasis
0.000 0.760 0.240
E22.0 Acromegaly and pituitary gigantism
0.000 0.760 0.240
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.760 0.239
M11 Other crystal arthropathies
0.001 0.762 0.237
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.763 0.237
S61 Open wound of wrist and hand
0.236 0.764 0.000
E27.9 Disorder of adrenal gland, unspecified
0.000 0.764 0.236
E28.9 Ovarian dysfunction, unspecified
0.000 0.764 0.236
E28.8 Other ovarian dysfunction
0.000 0.764 0.236
E28.3 Primary ovarian failure
0.000 0.764 0.236
E28.1 Androgen excess
0.000 0.764 0.236
E28.0 Oestrogen excess
0.000 0.764 0.236
L40.4 Guttate psoriasis
0.000 0.767 0.233
L40.3 Pustulosis palmaris et plantaris
0.000 0.767 0.233
L40.2 Acrodermatitis continua
0.000 0.767 0.233
L40.1 Generalised pustular psoriasis
0.000 0.767 0.233
E21.0 Primary hyperparathyroidism
0.000 0.769 0.230
M05.8 Other seropositive rheumatoid arthritis
0.001 0.772 0.227
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.001 0.772 0.227
M05.2 Rheumatoid vasculitis
0.001 0.772 0.227
M05.1 Rheumatoid lung disease
0.001 0.772 0.227
M05.0 Felty's syndrome
0.001 0.772 0.227
E26.9 Hyperaldosteronism, unspecified
0.000 0.774 0.226
E26.8 Other hyperaldosteronism
0.000 0.774 0.226
E26.1 Secondary hyperaldosteronism
0.000 0.774 0.226
S61.1 Open wound of finger(s) with damage to nail
0.222 0.778 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.780 0.220
M07.6 Other enteropathic arthropathies
0.001 0.782 0.217
M07.5 Arthropathy in ulcerative colitis
0.001 0.782 0.217
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.001 0.782 0.217
M07.2 Psoriatic spondylitis
0.001 0.782 0.217
M07.1 Arthritis mutilans
0.001 0.782 0.217
M07.0 Distal interphalangeal psoriatic arthropathy
0.001 0.782 0.217
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.786 0.214
E25.9 Adrenogenital disorder, unspecified
0.001 0.787 0.213
E25.8 Other adrenogenital disorders
0.001 0.787 0.213
E24.8 Other Cushing's syndrome
0.000 0.787 0.212
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.787 0.212
E24.3 Ectopic ACTH syndrome
0.000 0.787 0.212
E24.2 Drug-induced Cushing's syndrome
0.000 0.787 0.212
E24.1 Nelson's syndrome
0.000 0.787 0.212
E24.0 Pituitary-dependent Cushing's disease
0.000 0.787 0.212
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.793 0.206
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.793 0.206
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.793 0.206
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.793 0.206
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.793 0.206
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.793 0.206
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.793 0.206
E29.9 Testicular dysfunction, unspecified
0.000 0.794 0.206
E29.8 Other testicular dysfunction
0.000 0.794 0.206
E29.0 Testicular hyperfunction
0.000 0.794 0.206
E28.2 Polycystic ovarian syndrome
0.000 0.797 0.203
E23.7 Disorder of pituitary gland, unspecified
0.000 0.802 0.198
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.803 0.197
E23.1 Drug-induced hypopituitarism
0.000 0.803 0.197
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.806 0.194
L40-L45 Papulosquamous disorders
0.000 0.806 0.194
M10 Gout
0.001 0.806 0.193
S61.9 Open wound of wrist and hand, part unspecified
0.193 0.807 0.000
E23.2 Diabetes insipidus
0.000 0.809 0.191
M07.38 Other psoriatic arthropathies (Other)
0.000 0.811 0.189
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.811 0.189
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.811 0.189
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.811 0.189
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.811 0.189
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.811 0.189
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.811 0.189
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.811 0.189
M08.9 Juvenile arthritis, unspecified
0.001 0.815 0.184
M08.8 Other juvenile arthritis
0.001 0.815 0.184
M08.4 Pauciarticular juvenile arthritis
0.001 0.815 0.184
M08.3 Juvenile polyarthritis (seronegative)
0.001 0.815 0.184
M08.2 Juvenile arthritis with systemic onset
0.001 0.815 0.184
M08.1 Juvenile ankylosing spondylitis
0.001 0.815 0.184
M08.0 Juvenile rheumatoid arthritis
0.001 0.815 0.184
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.001 0.815 0.184
M09.2 Juvenile arthritis in ulcerative colitis
0.001 0.815 0.184
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.001 0.815 0.184
M09.0 Juvenile arthritis in psoriasis
0.001 0.815 0.184
M12.8 Other specific arthropathies, not elsewhere classified
0.001 0.815 0.184
M12.5 Traumatic arthropathy
0.001 0.815 0.184
M12.4 Intermittent hydrarthrosis
0.001 0.815 0.184
M12.3 Palindromic rheumatism
0.001 0.815 0.184
M12.2 Villonodular synovitis (pigmented)
0.001 0.815 0.184
M12.1 Kaschin-Beck disease
0.001 0.815 0.184
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.001 0.815 0.184
M14.8 Arthropathies in other specified diseases classified elsewhere
0.001 0.818 0.181
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.001 0.818 0.181
M14.4 Arthropathy in amyloidosis
0.001 0.818 0.181
M14.3 Lipoid dermatoarthritis
0.001 0.818 0.181
M14.2 Diabetic arthropathy
0.001 0.818 0.181
M14.1 Crystal arthropathy in other metabolic disorders
0.001 0.818 0.181
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.001 0.818 0.181
E26.0 Primary hyperaldosteronism
0.001 0.821 0.178
M14.6 Neuropathic arthropathy
0.001 0.822 0.177
E34.5 Androgen resistance syndrome
0.001 0.825 0.174
E34.4 Constitutional tall stature
0.001 0.825 0.174
E34.3 Short stature, not elsewhere classified
0.001 0.825 0.174
E34.2 Ectopic hormone secretion, not elsewhere classified
0.001 0.825 0.174
E34.1 Other hypersecretion of intestinal hormones
0.001 0.825 0.174
E23.6 Other disorders of pituitary gland
0.000 0.825 0.174
M11.9 Crystal arthropathy, unspecified
0.001 0.829 0.170
M11.8 Other specified crystal arthropathies
0.001 0.829 0.170
M11.1 Familial chondrocalcinosis
0.001 0.829 0.170
M11.0 Hydroxyapatite deposition disease
0.001 0.829 0.170
M05.09 Felty's syndrome (Site unspecified)
0.001 0.836 0.163
M05.08 Felty's syndrome (Other)
0.001 0.836 0.163
M05.07 Felty's syndrome (Ankle and foot)
0.001 0.836 0.163
M05.06 Felty's syndrome (Lower leg)
0.001 0.836 0.163
M05.05 Felty's syndrome (Pelvic region and thigh)
0.001 0.836 0.163
M05.04 Felty's syndrome (Hand)
0.001 0.836 0.163
M05.03 Felty's syndrome (Forearm)
0.001 0.836 0.163
M05.02 Felty's syndrome (Upper arm)
0.001 0.836 0.163
M05.01 Felty's syndrome (Shoulder region)
0.001 0.836 0.163
M05.00 Felty's syndrome (Multiple sites)
0.001 0.836 0.163
M05.19 Rheumatoid lung disease (Site unspecified)
0.001 0.836 0.163
M05.18 Rheumatoid lung disease (Other)
0.001 0.836 0.163
M05.17 Rheumatoid lung disease (Ankle and foot)
0.001 0.836 0.163
M05.16 Rheumatoid lung disease (Lower leg)
0.001 0.836 0.163
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.001 0.836 0.163
M05.14 Rheumatoid lung disease (Hand)
0.001 0.836 0.163
M05.13 Rheumatoid lung disease (Forearm)
0.001 0.836 0.163
M05.12 Rheumatoid lung disease (Upper arm)
0.001 0.836 0.163
M05.11 Rheumatoid lung disease (Shoulder region)
0.001 0.836 0.163
M05.10 Rheumatoid lung disease (Multiple sites)
0.001 0.836 0.163
M05.29 Rheumatoid vasculitis (Site unspecified)
0.001 0.836 0.163
M05.28 Rheumatoid vasculitis (Other)
0.001 0.836 0.163
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.001 0.836 0.163
M05.26 Rheumatoid vasculitis (Lower leg)
0.001 0.836 0.163
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.001 0.836 0.163
M05.24 Rheumatoid vasculitis (Hand)
0.001 0.836 0.163
M05.23 Rheumatoid vasculitis (Forearm)
0.001 0.836 0.163
M05.22 Rheumatoid vasculitis (Upper arm)
0.001 0.836 0.163
M05.21 Rheumatoid vasculitis (Shoulder region)
0.001 0.836 0.163
M05.20 Rheumatoid vasculitis (Multiple sites)
0.001 0.836 0.163
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.001 0.836 0.163
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.001 0.836 0.163
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.001 0.836 0.163
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.001 0.836 0.163
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.001 0.836 0.163
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.001 0.836 0.163
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.001 0.836 0.163
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.001 0.836 0.163
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.001 0.836 0.163
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.001 0.836 0.163
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.001 0.836 0.163
M05.88 Other seropositive rheumatoid arthritis (Other)
0.001 0.836 0.163
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.001 0.836 0.163
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.001 0.836 0.163
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.001 0.836 0.163
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.001 0.836 0.163
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.001 0.836 0.163
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.001 0.836 0.163
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.001 0.836 0.163
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.001 0.836 0.163
M13 Other arthritis
0.001 0.836 0.163
E07.9 Disorder of thyroid, unspecified
0.001 0.839 0.160
S61.7 Multiple open wounds of wrist and hand
0.159 0.841 0.000
E34.0 Carcinoid syndrome
0.001 0.842 0.157
E04.1 Non-toxic single thyroid nodule
0.000 0.843 0.157
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.001 0.843 0.156

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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